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Most cancer tissues showed moderate granular staining in the cytoplasm. A few cases of prostate, gastric and pancreatic cancers showed strong positivity. Gliomas and lymphomas were weakly stained or negative.
GENE INFORMATION
Gene name
REXO2 (HGNC Symbol)
Synonyms
CGI-114, DKFZP566E144, SFN
Description
RNA exonuclease 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]