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A majority of malignant cells showed weak to moderate cytoplasmic and membranous positivity. Few cases of malignant carcinoids and prostate cancers were strongly stained. Several cases of squamous cell carcinomas, malignant lymphomas and renal cancers were negative.
GENE INFORMATION
Gene name
HAUS4 (HGNC Symbol)
Synonyms
C14orf94, FLJ20424
Description
HAUS augmin-like complex, subunit 4 (HGNC Symbol)
Entrez gene summary
This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]