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PATHOLOGY ATLAS CERVICAL CANCER

GENE/PROTEIN

Antibody validation

Dictionary

Cervical cancer

CERVICAL CANCER - Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival, using best separation (to the left) and median separation (to the right). Patients were divided based on level of expression into one of the two groups "low" or "high". Below each Kaplan-Meier plot, corresponding expression cutoff, 5-year survival for patients with high expression, 5-year survival for patients with low expression and log-rank P value are displayed. For melanoma and glioma, 3-year survival is shown. The survival analysis is described in Assays & Annotation.

The tabs at the top of the survival analysis section can be used to switch between the different cancer subtypes.

Best separation

Median separation

Expression cutoffi

5-year survival for patients with higher expression than the expression cutoff.

11.3 FPKM 13.0 FPKM

5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

62% 65%

5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

75% 68%

Log-rank P valuei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

3.99e-2 3.81e-1

Interactive survival scatter plot (individual patient data)i

The Scatter Survival plot shows the clinical status for all individuals in the patient cohort, based on the same data as in the Kaplan-Meier plots. Living patients are shown in blue and deceased patients in red. The x-axis shows the expression levels (FPKM) of the investigated gene at the time of diagnosis and the y-axis shows the number of years of survival (living years) after the diagnosis.

Individual patient data is displayed in an interactive plot and can be filtered by clicking on one or several category buttons to the left. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be changed to "x linear" by clicking on the "x log" button on the left. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.




Stage:

TCGA RNA samplesi

RNA-seq data is reported as median FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average FPKM

13.8

Number of samples

291

Samples

Sample

Description

FPKM

TCGA-C5-A8YT-01A 36 years, female, white 49.4
TCGA-Q1-A73R-01A 45 years, female, white 35.6
TCGA-VS-A9UL-01A 79 years, female, white 31.8
TCGA-EA-A5ZE-01A 54 years, female, asian 29.7
TCGA-VS-A9UJ-01A 55 years, female 28.5
TCGA-DS-A7WF-01A 41 years, female 28.0
TCGA-FU-A3TX-01A 78 years, female 28.0
TCGA-C5-A8YR-01A 56 years, female, white 27.6
TCGA-2W-A8YY-01A 51 years, female, white 26.5
TCGA-VS-A9UR-01A 53 years, female, white 26.4
TCGA-C5-A902-01A 35 years, female, black or african american 26.3
TCGA-VS-A9UB-01A 54 years, female 26.3
TCGA-C5-A1BF-01B 46 years, female, white 25.3
TCGA-LP-A4AX-01A 45 years, female, asian 24.9
TCGA-LP-A4AW-01A 52 years, female, asian 24.5
TCGA-VS-A9U5-01A 57 years, female, white 23.8
TCGA-Q1-A6DT-01A 55 years, female, white 23.7
TCGA-VS-A9V3-01A 62 years, female, white 23.7
TCGA-EK-A2R8-01A 48 years, female, white 23.6
TCGA-DS-A3LQ-01A 46 years, female 23.6
TCGA-VS-A94W-01A 39 years, female, white 23.3
TCGA-VS-A9UO-01A 43 years, female, white 23.3
TCGA-EA-A410-01A 51 years, female, white 22.9
TCGA-EX-A69M-01A 62 years, female, white 22.6
TCGA-EK-A2IR-01A 48 years, female, white 21.3
TCGA-JW-A5VG-01A 35 years, female, american indian or alaska native 21.2
TCGA-C5-A7CG-01A 55 years, female, white 20.9
TCGA-C5-A7CJ-01A 42 years, female, white 20.9
TCGA-LP-A4AU-01A 35 years, female, asian 20.1
TCGA-EA-A1QS-01A 46 years, female, white 20.1
TCGA-C5-A8XJ-01A 74 years, female, white 20.0
TCGA-EA-A3HS-01A 35 years, female, white 19.8
TCGA-JW-A69B-01A 44 years, female, white 19.7
TCGA-MA-AA41-01A 33 years, female, white 19.5
TCGA-EA-A556-01A 38 years, female, white 19.5
TCGA-C5-A8XI-01A 69 years, female, black or african american 19.2
TCGA-ZJ-A8QQ-01A 24 years, female, white 19.1
TCGA-EK-A2PK-01A 43 years, female, white 18.9
TCGA-MY-A913-01A 28 years, female, black or african american 18.8
TCGA-VS-A8EH-01A 56 years, female 18.7
TCGA-VS-A9UQ-01A 32 years, female 18.5
TCGA-VS-A94X-01A 40 years, female, black or african american 18.5
TCGA-C5-A8ZZ-01A 41 years, female, white 18.4
TCGA-FU-A3YQ-01A 35 years, female, white 18.4
TCGA-C5-A907-01A 47 years, female, white 18.3
TCGA-MU-A5YI-01A 60 years, female, black or african american 18.3
TCGA-IR-A3L7-01A 37 years, female, white 18.2
TCGA-EX-A3L1-01A 32 years, female, white 18.2
TCGA-C5-A1MI-01A 50 years, female, white 18.1
TCGA-VS-A9UV-01A 74 years, female 17.9
TCGA-HM-A3JJ-01A 40 years, female, black or african american 17.9
TCGA-LP-A7HU-01A 53 years, female, asian 17.9
TCGA-VS-A8Q9-01A 79 years, female, white 17.8
TCGA-C5-A1BL-01A 32 years, female, white 17.8
TCGA-FU-A57G-01A 49 years, female, white 17.6
TCGA-VS-A8EK-01A 65 years, female, white 17.4
TCGA-MA-AA43-01A 48 years, female, white 17.4
TCGA-VS-A8QM-01A 47 years, female 17.4
TCGA-DS-A7WH-01A 34 years, female, white 17.3
TCGA-EA-A3HU-01A 43 years, female, white 17.2
TCGA-HM-A3JK-01A 64 years, female, white 17.1
TCGA-DS-A1OC-01A 47 years, female, white 16.9
TCGA-EK-A2RJ-01A 51 years, female, white 16.9
TCGA-VS-A8Q8-01A 26 years, female, white 16.8
TCGA-IR-A3LH-01A 49 years, female, black or african american 16.8
TCGA-ZJ-AAXU-01A 51 years, female, white 16.7
TCGA-VS-A9V5-01A 50 years, female, white 16.7
TCGA-C5-A8XK-01A 30 years, female, black or african american 16.7
TCGA-EA-A3HR-01A 57 years, female, white 16.5
TCGA-C5-A7CL-01A 48 years, female, white 16.5
TCGA-ZX-AA5X-01A 64 years, female, white 16.5
TCGA-VS-A9UM-01A 39 years, female, black or african american 16.3
TCGA-VS-A9UP-01A 43 years, female 16.3
TCGA-JW-A5VI-01A 45 years, female, american indian or alaska native 16.2
TCGA-HM-A6W2-01A 35 years, female, black or african american 16.2
TCGA-EA-A6QX-01A 49 years, female, asian 16.2
TCGA-VS-A8QH-01A 76 years, female, white 16.1
TCGA-MA-AA3Y-01A 48 years, female, white 16.1
TCGA-VS-A9UZ-01A 61 years, female, white 16.1
TCGA-FU-A3HZ-01A 64 years, female, white 16.0
TCGA-C5-A1MP-01A 34 years, female, black or african american 16.0
TCGA-C5-A7CK-01A 58 years, female, white 16.0
TCGA-EA-A4BA-01A 49 years, female, white 16.0
TCGA-C5-A7XC-01A 26 years, female, white 15.9
TCGA-C5-A7CO-01A 68 years, female, white 15.8
TCGA-VS-A9UY-01A 29 years, female 15.7
TCGA-VS-A9V4-01A 63 years, female, white 15.7
TCGA-VS-AA62-01A 51 years, female, white 15.7
TCGA-C5-A3HD-01B 51 years, female, white 15.7
TCGA-EK-A2H0-01A 24 years, female, white 15.7
TCGA-VS-A9V2-01A 29 years, female, white 15.6
TCGA-VS-A9UT-01A 72 years, female, asian 15.5
TCGA-VS-A9UU-01A 42 years, female 15.5
TCGA-C5-A1MJ-01A 61 years, female, white 15.4
TCGA-C5-A0TN-01A 21 years, female, black or african american 15.3
TCGA-MA-AA3W-01A 54 years, female, white 15.3
TCGA-UC-A7PD-01A 21 years, female, american indian or alaska native 15.3
TCGA-C5-A3HL-01A 76 years, female, white 15.2
TCGA-C5-A1BJ-01A 34 years, female, white 15.2
TCGA-DR-A0ZL-01A 53 years, female, asian 15.1
TCGA-VS-A952-01A 66 years, female, white 15.0
TCGA-VS-A8QA-01A 44 years, female 14.9
TCGA-FU-A3TQ-01A 55 years, female, white 14.9
TCGA-EX-A8YF-01A 44 years, female, white 14.8
TCGA-C5-A3HF-01A 24 years, female, white 14.8
TCGA-4J-AA1J-01A 31 years, female, white 14.8
TCGA-DG-A2KK-01A 51 years, female 14.8
TCGA-C5-A2M1-01A 37 years, female, white 14.8
TCGA-EA-A1QT-01A 47 years, female, white 14.6
TCGA-EK-A2H1-01A 20 years, female, white 14.5
TCGA-HM-A4S6-01A 51 years, female, white 14.5
TCGA-FU-A770-01A 33 years, female, white 14.4
TCGA-DG-A2KL-01A 53 years, female 14.4
TCGA-MY-A5BE-01A 42 years, female, black or african american 14.4
TCGA-Q1-A6DW-01A 44 years, female, white 14.3
TCGA-IR-A3LB-01A 53 years, female, white 14.2
TCGA-ZJ-AAXA-01A 64 years, female, white 14.2
TCGA-EA-A5FO-01A 59 years, female, white 14.2
TCGA-IR-A3LA-01A 60 years, female, white 14.2
TCGA-EX-A1H5-01A 58 years, female, black or african american 14.2
TCGA-FU-A3WB-01A 43 years, female, white 14.1
TCGA-JX-A5QV-01A 37 years, female, white 14.0
TCGA-C5-A1MN-01A 42 years, female, white 14.0
TCGA-IR-A3LC-01A 40 years, female, white 14.0
TCGA-JW-AAVH-01A 46 years, female, white 13.9
TCGA-EA-A3HT-01A 68 years, female, white 13.9
TCGA-C5-A2LT-01A 38 years, female, white 13.8
TCGA-VS-A8EG-01A 36 years, female 13.7
TCGA-C5-A3HE-01A 44 years, female, white 13.7
TCGA-FU-A3NI-01A 45 years, female, white 13.6
TCGA-C5-A1M6-01A 55 years, female, white 13.5
TCGA-VS-A8EB-01A 41 years, female, white 13.4
TCGA-C5-A1M5-01A 53 years, female, white 13.4
TCGA-EK-A3GN-01A 47 years, female, white 13.4
TCGA-JW-A5VH-01A 53 years, female, american indian or alaska native 13.3
TCGA-C5-A7X3-01A 70 years, female, white 13.3
TCGA-VS-A959-01A 76 years, female 13.3
TCGA-VS-A8EI-01A 38 years, female, white 13.2
TCGA-MU-A8JM-01A 47 years, female, white 13.2
TCGA-GH-A9DA-01A 27 years, female, white 13.1
TCGA-VS-A958-01A 46 years, female, white 13.1
TCGA-EA-A3HQ-01A 60 years, female, white 13.1
TCGA-DS-A1O9-01A 75 years, female, white 13.1
TCGA-Q1-A73P-01A 45 years, female, white 13.1
TCGA-C5-A7UC-01A 48 years, female, white 13.0
TCGA-C5-A1MK-01A 79 years, female, white 13.0
TCGA-EA-A439-01A 50 years, female, asian 13.0
TCGA-DG-A2KM-01A 46 years, female 13.0
TCGA-BI-A0VR-01A 53 years, female, white 13.0
TCGA-VS-A94Z-01A 38 years, female, white 13.0
TCGA-HG-A2PA-01A 38 years, female, white 12.9
TCGA-LP-A5U2-01A 30 years, female, asian 12.9
TCGA-C5-A1M7-01A 37 years, female, white 12.8
TCGA-EA-A5ZF-01A 56 years, female, asian 12.8
TCGA-UC-A7PI-01A 45 years, female, white 12.7
TCGA-VS-A950-01A 42 years, female 12.6
TCGA-UC-A7PF-01A 44 years, female 12.6
TCGA-DS-A0VL-01A 25 years, female, white 12.6
TCGA-C5-A2M2-01A 56 years, female, white 12.6
TCGA-VS-A8QC-01A 51 years, female, white 12.5
TCGA-XS-A8TJ-01A 41 years, female, black or african american 12.4
TCGA-MU-A51Y-01A 27 years, female, white 12.3
TCGA-DS-A5RQ-01A 80 years, female, white 12.3
TCGA-C5-A7X8-01A 35 years, female, white 12.2
TCGA-FU-A2QG-01A 29 years, female, white 12.2
TCGA-C5-A1ML-01A 49 years, female, white 12.1
TCGA-C5-A1M9-01A 46 years, female, white 12.1
TCGA-C5-A7CM-01A 35 years, female, white 12.1
TCGA-ZJ-A8QR-01A 38 years, female, native hawaiian or other pacific islander 12.0
TCGA-EA-A97N-01A 38 years, female, white 12.0
TCGA-DS-A1OA-01A 77 years, female, asian 11.9
TCGA-VS-A9V1-01A 46 years, female, white 11.9
TCGA-C5-A2LS-01A 37 years, female, white 11.9
TCGA-EK-A2RE-01A 26 years, female, white 11.9
TCGA-VS-A9UC-01A 32 years, female 11.8
TCGA-ZJ-AAX4-01A 85 years, female, white 11.8
TCGA-EA-A5ZD-01A 40 years, female, asian 11.8
TCGA-VS-A9U6-01A 52 years, female, white 11.8
TCGA-IR-A3LF-01A 64 years, female, white 11.8
TCGA-C5-A1BN-01B 26 years, female, white 11.8
TCGA-VS-A94Y-01A 47 years, female, white 11.7
TCGA-EX-A449-01A 42 years, female, white 11.7
TCGA-C5-A1M8-01A 43 years, female, white 11.7
TCGA-DS-A0VK-01A 46 years, female, white 11.7
TCGA-VS-A957-01A 64 years, female, white 11.7
TCGA-VS-A8EC-01A 55 years, female, white 11.6
TCGA-Q1-A73O-01A 37 years, female 11.6
TCGA-FU-A40J-01A 38 years, female, white 11.6
TCGA-C5-A8XH-01A 39 years, female, white 11.6
TCGA-JW-A5VL-01A 37 years, female, american indian or alaska native 11.4
TCGA-Q1-A6DV-01A 36 years, female, asian 11.4
TCGA-VS-A9V0-01A 58 years, female 11.4
TCGA-VS-A8EJ-01A 60 years, female, white 11.4
TCGA-EA-A3QD-01A 59 years, female, white 11.3
TCGA-C5-A1BM-01A 78 years, female, black or african american 11.3
TCGA-C5-A1BQ-01C 65 years, female, white 11.3
TCGA-EA-A3QE-01A 45 years, female, white 11.3
TCGA-EK-A2R7-01A 45 years, female, white 11.3
TCGA-EA-A411-01A 50 years, female, white 11.2
TCGA-EK-A3GK-01A 33 years, female, white 11.2
TCGA-EK-A2IP-01A 28 years, female, white 11.1
TCGA-EK-A2RM-01A 40 years, female, white 11.1
TCGA-MY-A5BD-01A 62 years, female, white 11.1
TCGA-BI-A20A-01A 49 years, female, white 11.1
TCGA-Q1-A73Q-01A 46 years, female, white 11.1
TCGA-JW-A5VJ-01A 56 years, female, american indian or alaska native 11.0
TCGA-PN-A8MA-01A 43 years, female, black or african american 11.0
TCGA-IR-A3LI-01A 48 years, female, white 11.0
TCGA-EK-A2RA-01A 74 years, female 11.0
TCGA-IR-A3LK-01A 69 years, female, white 10.9
TCGA-WL-A834-01A female, white 10.9
TCGA-EK-A2RL-01A 33 years, female, black or african american 10.9
TCGA-C5-A901-01A 44 years, female, white 10.9
TCGA-Q1-A5R1-01A 32 years, female, white 10.9
TCGA-EK-A3GJ-01A 51 years, female, native hawaiian or other pacific islander 10.8
TCGA-EK-A2RC-01A 33 years, female 10.8
TCGA-EK-A2PI-01A 44 years, female, white 10.8
TCGA-EA-A44S-01A 31 years, female, white 10.6
TCGA-EX-A1H6-01B 38 years, female, white 10.6
TCGA-C5-A2LV-01A 36 years, female, black or african american 10.6
TCGA-C5-A1BE-01B 65 years, female, white 10.5
TCGA-C5-A1MH-01A 71 years, female, white 10.5
TCGA-EK-A2PM-01A 81 years, female, white 10.5
TCGA-EK-A2R9-01A 58 years, female, white 10.3
TCGA-MA-AA3Z-01A 43 years, female, white 10.3
TCGA-FU-A5XV-01A 32 years, female, white 10.3
TCGA-VS-A954-01A 67 years, female 10.2
TCGA-JX-A3Q0-01A 63 years, female, black or african american 10.2
TCGA-VS-A9UI-01A 76 years, female, white 10.1
TCGA-BI-A0VS-01A 48 years, female, white 10.1
TCGA-EA-A43B-01A 43 years, female, white 10.0
TCGA-MY-A5BF-01A 68 years, female, white 10.0
TCGA-FU-A23L-01A 60 years, female, white 9.9
TCGA-C5-A7CH-01A 43 years, female, white 9.9
TCGA-DS-A1OD-01A 49 years, female, white 9.8
TCGA-VS-A9UD-01A 73 years, female, white 9.8
TCGA-UC-A7PG-01A 44 years, female, white 9.6
TCGA-FU-A3HY-01A 47 years, female, white 9.6
TCGA-C5-A905-01A 37 years, female, black or african american 9.5
TCGA-RA-A741-01A 34 years, female, white 9.4
TCGA-C5-A1BI-01B 31 years, female, white 9.4
TCGA-EA-A3Y4-01A 40 years, female, white 9.3
TCGA-EA-A50E-01A 45 years, female, asian 9.3
TCGA-C5-A7UE-01A 45 years, female, white 9.3
TCGA-C5-A7UH-01A 55 years, female, white 9.2
TCGA-DS-A0VN-01A 47 years, female, white 9.1
TCGA-EX-A69L-01A 41 years, female, asian 9.1
TCGA-C5-A2LZ-01A 65 years, female, white 9.0
TCGA-DG-A2KH-01A 25 years, female 8.8
TCGA-DR-A0ZM-01A 61 years, female, white 8.8
TCGA-JX-A3Q8-01A 40 years, female, asian 8.8
TCGA-IR-A3LL-01A 60 years, female, white 8.7
TCGA-EK-A2RK-01A 67 years, female, white 8.7
TCGA-VS-A9U7-01A 30 years, female, white 8.6
TCGA-MA-AA42-01A 75 years, female, white 8.5
TCGA-C5-A7X5-01A 72 years, female, black or african american 8.5
TCGA-VS-A8QF-01A 42 years, female, white 8.4
TCGA-C5-A8YQ-01A 79 years, female, white 8.4
TCGA-VS-A9UH-01A 53 years, female, black or african american 8.4
TCGA-LP-A5U3-01A 40 years, female, asian 8.2
TCGA-EK-A2GZ-01A 64 years, female, black or african american 7.9
TCGA-DS-A0VM-01A 51 years, female, white 7.7
TCGA-EK-A2PL-01A 36 years, female, white 7.5
TCGA-C5-A1MQ-01A 35 years, female, white 7.5
TCGA-Q1-A73S-01A 33 years, female, white 7.4
TCGA-VS-A953-01A 63 years, female 7.4
TCGA-JX-A3PZ-01A 25 years, female, white 7.3
TCGA-EA-A5O9-01A 39 years, female, white 7.3
TCGA-JW-A5VK-01A 43 years, female, black or african american 6.9
TCGA-C5-A7UI-01A 42 years, female, black or african american 6.9
TCGA-EA-A78R-01A 54 years, female, asian 6.8
TCGA-VS-A8EL-01A 38 years, female, black or african american 6.8
TCGA-C5-A2LX-01A 54 years, female, white 6.7
TCGA-EK-A2RB-01A 48 years, female, white 6.7
TCGA-C5-A2LY-01A 30 years, female, white 6.5
TCGA-C5-A1BK-01B 36 years, female, black or african american 6.5
TCGA-R2-A69V-01A 42 years, female, white 6.4
TCGA-MA-AA3X-01A 50 years, female, black or african american 6.3
TCGA-EK-A2RN-01A 45 years, female, white 6.3
TCGA-Q1-A5R2-01A 64 years, female, white 6.2
TCGA-EK-A2RO-01A 59 years, female, american indian or alaska native 6.1
TCGA-DS-A7WI-01A 43 years, female, white 6.0
TCGA-JW-A852-01A 42 years, female, white 5.6
TCGA-EK-A2PG-01A 89 years, female, black or african american 5.6
TCGA-DS-A1OB-01A 45 years, female, white 5.2
TCGA-FU-A23K-01A 28 years, female, white 3.9
TCGA-C5-A1ME-01A 41 years, female, white 3.4
TCGA-C5-A1MF-01A 49 years, female, white 3.3
TCGA-Q1-A5R3-01A 56 years, female, white 3.0
TCGA-FU-A3EO-01A 55 years, female, white 2.9
TCGA-DG-A2KJ-01A 50 years, female 1.0
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CERVICAL CANCER - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

Antibody HPA027251

Antibody HPA027280

Antibody HPA028409

Antibody CAB002686

 Antibody staining
  High
  Medium
  Low
  Not detected
     
 Intensity
  Strong
  Moderate
  Weak
  Negative
     
 Quantity
  >75%
  75%-25%
  <25%
  Rare
  Negative
     
 Location
  Cytoplasmic/membranous,nuclear
  Cytoplasmic/membranous
  Nuclear
  None
     

Click images for details




























































































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