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Most malignant cells showed weak cytoplasmic immunoreactivity or were negative. Additional nuclear positivity was observed in several cases.
GENE INFORMATION
Gene name
DNAL4 (HGNC Symbol)
Synonyms
dJ327J16, PIG27
Description
Dynein, axonemal, light chain 4 (HGNC Symbol)
Entrez gene summary
This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. [provided by RefSeq, Dec 2014]
MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)