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PATHOLOGY ATLAS GLIOMA

GENE/PROTEIN

Antibody validation

Dictionary

Glioma

GLIOMA - Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival, using best separation (to the left) and median separation (to the right). Patients were divided based on level of expression into one of the two groups "low" or "high". Below each Kaplan-Meier plot, corresponding expression cutoff, 5-year survival for patients with high expression, 5-year survival for patients with low expression and log-rank P value are displayed. For melanoma and glioma, 3-year survival is shown. The survival analysis is described in Assays & Annotation.

The tabs at the top of the survival analysis section can be used to switch between the different cancer subtypes.

Best separation

Median separation

Expression cutoffi

5-year survival for patients with higher expression than the expression cutoff.

36.7 FPKM 28.6 FPKM

3-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

15% 14%

3-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

2% 0%

Log-rank P valuei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

8.95e-2 2.15e-1

Interactive survival scatter plot (individual patient data)i

The Scatter Survival plot shows the clinical status for all individuals in the patient cohort, based on the same data as in the Kaplan-Meier plots. Living patients are shown in blue and deceased patients in red. The x-axis shows the expression levels (FPKM) of the investigated gene at the time of diagnosis and the y-axis shows the number of years of survival (living years) after the diagnosis.

Individual patient data is displayed in an interactive plot and can be filtered by clicking on one or several category buttons to the left. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be changed to "x linear" by clicking on the "x log" button on the left. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.




Stage:

TCGA RNA samplesi

RNA-seq data is reported as median FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average FPKM

30.7

Number of samples

153

Samples

Sample

Description

FPKM

TCGA-26-5133-01A 59 years, male, white 93.2
TCGA-16-1045-01B 49 years, female, white 65.2
TCGA-15-1444-01A 21 years, male, white 62.8
TCGA-26-1442-01A 43 years, male, white 57.7
TCGA-28-5215-01A 62 years, female, white 56.6
TCGA-06-0184-01A 63 years, male, white 56.2
TCGA-02-0047-01A 78 years, male, white 55.9
TCGA-28-1747-01C 44 years, male, white 51.5
TCGA-76-4931-01A 70 years, female, white 50.1
TCGA-19-1787-01B 49 years, male, white 49.1
TCGA-32-1980-01A 72 years, male, white 48.7
TCGA-06-0646-01A 61 years, male, white 48.2
TCGA-06-2561-01A 53 years, female, white 47.0
TCGA-28-5220-01A 67 years, male, white 46.7
TCGA-06-0132-01A 49 years, male, white 45.2
TCGA-32-2616-01A 48 years, female, white 44.6
TCGA-27-1834-01A 56 years, male, white 42.7
TCGA-06-5411-01A 51 years, male, white 42.5
TCGA-28-5216-01A 52 years, male, white 42.0
TCGA-28-5209-01A 66 years, female, white 41.9
TCGA-16-0846-01A 85 years, male, white 41.6
TCGA-06-5858-01A 45 years, female, white 41.2
TCGA-19-2619-01A 55 years, female, black or african american 41.2
TCGA-06-0157-01A 63 years, female, white 41.0
TCGA-06-2557-01A 76 years, male, black or african american 40.8
TCGA-28-2499-01A 59 years, male, white 40.8
TCGA-27-1837-01A 36 years, male, white 40.7
TCGA-19-2629-01A 60 years, male, white 40.4
TCGA-28-2513-01A 69 years, female, white 40.3
TCGA-06-0125-01A 63 years, female, white 40.3
TCGA-32-2638-01A 67 years, male, white 39.9
TCGA-12-5299-01A 56 years, female, white 39.8
TCGA-27-2521-01A 34 years, male, white 39.5
TCGA-12-1597-01B 62 years, female, white 39.2
TCGA-28-5204-01A 72 years, male, white 39.1
TCGA-19-1390-01A 63 years, female, white 39.0
TCGA-14-1825-01A 70 years, male, white 38.0
TCGA-26-5135-01A 72 years, female, white 37.6
TCGA-06-0187-01A 69 years, male, white 37.3
TCGA-06-0749-01A 50 years, male, black or african american 37.2
TCGA-76-4932-01A 50 years, female, white 37.2
TCGA-28-2514-01A 45 years, male, asian 36.9
TCGA-06-2564-01A 50 years, male, white 36.9
TCGA-12-0618-01A 49 years, male, white 36.5
TCGA-41-5651-01A 59 years, female, black or african american 36.4
TCGA-14-0790-01B 64 years, female, white 36.3
TCGA-41-2572-01A 67 years, male, white 36.0
TCGA-06-0174-01A 54 years, male, white 35.3
TCGA-06-2563-01A 72 years, female, white 34.4
TCGA-12-0616-01A 36 years, female, white 34.4
TCGA-06-0644-01A 71 years, male, black or african american 33.6
TCGA-41-2571-01A 89 years, male, white 33.3
TCGA-06-0750-01A 43 years, male, white 33.2
TCGA-06-0211-01B 47 years, male, white 32.9
TCGA-28-1753-01A 53 years, male, white 32.8
TCGA-06-0686-01A 53 years, male, white 32.4
TCGA-27-2528-01A 62 years, male, white 32.4
TCGA-06-0190-01A 62 years, male, white 32.3
TCGA-06-0645-01A 56 years, female, white 32.1
TCGA-06-5414-01A 61 years, male, white 32.0
TCGA-06-2570-01A 21 years, female, white 31.7
TCGA-26-5139-01A 65 years, female, white 31.6
TCGA-32-4213-01A 47 years, female, white 31.6
TCGA-27-2526-01A 79 years, female, white 31.2
TCGA-06-5856-01A 58 years, male, white 31.0
TCGA-06-5859-01A 63 years, male, white 30.8
TCGA-12-3653-01A 34 years, female, white 30.8
TCGA-06-5412-01A 78 years, female, white 30.2
TCGA-41-4097-01A 63 years, female, white 30.0
TCGA-02-2485-01A 53 years, male, black or african american 30.0
TCGA-28-5207-01A 71 years, male, white 29.6
TCGA-32-2632-01A 80 years, male, white 29.4
TCGA-06-0178-01A 39 years, male, white 29.1
TCGA-06-0168-01A 59 years, female, white 29.0
TCGA-12-3650-01A 46 years, male, white 28.9
TCGA-06-5410-01A 72 years, female, white 28.7
TCGA-06-0649-01B 73 years, female, black or african american 28.6
TCGA-19-2624-01A 51 years, male, white 28.6
TCGA-28-2509-01A 77 years, female, white 28.4
TCGA-06-5416-01A 23 years, female, white 28.4
TCGA-32-1982-01A 76 years, female, white 27.9
TCGA-14-0817-01A 69 years, female, white 27.9
TCGA-06-0138-01A 43 years, male, white 27.6
TCGA-27-1832-01A 59 years, female, white 27.5
TCGA-06-2569-01A 24 years, female, black or african american 27.5
TCGA-06-0743-01A 69 years, male, white 27.4
TCGA-06-0238-01A 46 years, male, white 27.3
TCGA-06-0210-01A 72 years, female, white 27.2
TCGA-06-2565-01A 59 years, male, asian 26.8
TCGA-14-1823-01A 58 years, female, white 26.7
TCGA-26-5134-01A 74 years, male, white 26.5
TCGA-76-4929-01A 76 years, female, white 26.2
TCGA-06-0745-01A 59 years, male, white 26.2
TCGA-32-2615-01A 62 years, male, white 26.2
TCGA-32-1970-01A 59 years, male, white 26.1
TCGA-06-2559-01A 83 years, male, white 26.1
TCGA-06-0129-01A 30 years, male, asian 26.1
TCGA-76-4928-01B 85 years, female, white 26.1
TCGA-14-0789-01A 54 years, male, white 26.0
TCGA-76-4927-01A 58 years, male, white 25.9
TCGA-06-0158-01A 73 years, male, white 25.5
TCGA-32-5222-01A 66 years, male, white 25.2
TCGA-06-0882-01A 30 years, male, white 25.1
TCGA-08-0386-01A 74 years, male, white 24.7
TCGA-12-0619-01A 60 years, male, white 24.4
TCGA-28-5218-01A 63 years, male, white 24.4
TCGA-27-2524-01A 56 years, male, white 24.3
TCGA-32-2634-01A 82 years, male, white 23.7
TCGA-14-0781-01B 49 years, male, black or african american 22.9
TCGA-41-3915-01A 48 years, male, white 22.9
TCGA-02-2483-01A 43 years, male, asian 22.4
TCGA-76-4926-01B 68 years, male, white 22.4
TCGA-06-5417-01A 45 years, female, white 22.1
TCGA-06-2558-01A 75 years, female, white 22.0
TCGA-12-3652-01A 60 years, male, white 21.7
TCGA-27-2519-01A 48 years, male, white 21.5
TCGA-19-2625-01A 76 years, female, white 21.3
TCGA-28-5213-01A 72 years, male, white 20.9
TCGA-27-1830-01A 57 years, male, white 20.8
TCGA-14-1829-01A 57 years, male, black or african american 20.7
TCGA-06-2567-01A 65 years, male, white 20.6
TCGA-19-2620-01A 70 years, male, white 20.6
TCGA-06-0130-01A 54 years, male, white 20.5
TCGA-19-5960-01A 56 years, male, white 20.5
TCGA-12-5295-01A 60 years, female, white 20.4
TCGA-14-1034-01A 60 years, female 20.4
TCGA-19-4065-01A 36 years, male, white 20.4
TCGA-02-0055-01A 62 years, female, white 20.3
TCGA-06-0747-01A 53 years, male, white 20.1
TCGA-06-1804-01A 81 years, female, white 19.7
TCGA-06-0219-01A 67 years, male, white 19.4
TCGA-12-0821-01A 62 years, male, white 19.3
TCGA-06-5408-01A 54 years, female, white 19.3
TCGA-06-0878-01A 74 years, male, white 18.8
TCGA-06-5413-01A 67 years, male, white 18.5
TCGA-26-5136-01B 78 years, female, white 18.5
TCGA-76-4925-01A 76 years, male, white 18.3
TCGA-27-1835-01A 53 years, female, white 17.9
TCGA-14-0871-01A 75 years, female, white 17.8
TCGA-28-5208-01A 52 years, male, white 17.7
TCGA-02-2486-01A 64 years, male, white 17.4
TCGA-06-0141-01A 62 years, male, white 17.0
TCGA-06-0156-01A 57 years, male, white 16.5
TCGA-26-5132-01A 74 years, male, white 16.3
TCGA-06-5418-01A 75 years, female, white 16.3
TCGA-06-2562-01A 81 years, male, white 15.9
TCGA-06-0139-01A 40 years, male, white 14.8
TCGA-27-2523-01A 63 years, male, white 14.4
TCGA-06-0744-01A 67 years, male, white 14.3
TCGA-15-0742-01A 65 years, male, white 13.1
TCGA-14-0787-01A 69 years, male, asian 13.0
TCGA-14-2554-01A 52 years, female, white 11.2
TCGA-27-1831-01A 66 years, male, white 10.3
Show all

GLIOMA - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

Antibody HPA001097

 Antibody staining
  High
  Medium
  Low
  Not detected
  
 Intensity
  Strong
  Moderate
  Weak
  Negative
  
 Quantity
  >75%
  75%-25%
  <25%
  Rare
  Negative
  
 Location
  Cytoplasmic/membranous,nuclear
  Cytoplasmic/membranous
  Nuclear
  None
  

Click images for details






















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