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Most cancer cells displayed weak to moderate cytoplasmic positivity with additional membranous and nuclear staining in some cases. A majority squamous cell carcinomas, breast, prostate and ovarian cancers were negative.
GENE INFORMATION
Gene name
PFDN4 (HGNC Symbol)
Synonyms
C-1, C1, PFD4
Description
Prefoldin subunit 4 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]