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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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ZNFX1
  • TISSUE

  • CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

ZNFX1

Gene description

Zinc finger, NFX1-type containing 1

Protein class

Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA046629
SHOW MORE

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA046629

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Moderate to strong cytoplasmic immunoreactivity was observed in cancer tissues. Several gliomas were weakly stained.

GENE INFORMATION

Gene name

ZNFX1 (HGNC Symbol)

Synonyms

FLJ11277, KIAA1404

Description

Zinc finger, NFX1-type containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

20

Cytoband

q13.13

Chromosome location (bp)

49237946 - 49278426

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124201 (version 83.38)

Entrez gene

57169

UniProt

Q9P2E3 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9P2E3

Antibodypedia

ZNFX1 antibodies

PROTEIN BROWSER

ZNFX1-001
ZNFX1-002
ZNFX1-003
ZNFX1-004
ZNFX1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZNFX1-001
ENSP00000360817
ENST00000371752
Q9P2E3 [Direct mapping]
NFX1-type zinc finger-containing protein 1
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Yet undefined DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005488 [binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0044822 [poly(A) RNA binding]
GO:0046872 [metal ion binding]
Show all
1918 aa
220.2 kDa
No 0
ZNFX1-002
ENSP00000360809
ENST00000371744
Q5JXR5 [Direct mapping]
NFX1-type zinc finger-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
934 aa
107.9 kDa
No 0
ZNFX1-003
ENSP00000413800
ENST00000455070
Q5JXR7 [Direct mapping]
NFX1-type zinc finger-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
707 aa
81.2 kDa
No 0
ZNFX1-004
ENSP00000360819
ENST00000371754
Q5JXR6 [Direct mapping]
NFX1-type zinc finger-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
Show all
1270 aa
146.2 kDa
No 0
ZNFX1-201
ENSP00000379412
ENST00000396105
Q9P2E3 [Direct mapping]
NFX1-type zinc finger-containing protein 1
Show all
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Yet undefined DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005488 [binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0044822 [poly(A) RNA binding]
GO:0046872 [metal ion binding]
Show all
1918 aa
220.2 kDa
No 0

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