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A single case of malignant lymphoma showed moderate cytoplasmic staining while a fraction of tumor cells in a rare case of pancreatic cancer displayed moderate cytoplasmic and nuclear positivity. Remaining malignant tissues were negative.
GENE INFORMATION
Gene name
ZBP1 (HGNC Symbol)
Synonyms
C20orf183, DAI, dJ718J7.3, DLM-1, DLM1
Description
Z-DNA binding protein 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]