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Majority of malignant cells displayed moderate to strong cytoplasmic positivity which in a few malignancies was combined with nuclear staining. Membranous staining was observed in colorectal cancers. A majority of malignant gliomas, thyroid and female genital cancers were weakly stained or negative.
GENE INFORMATION
Gene name
KNSTRN (HGNC Symbol)
Synonyms
C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1
Description
Kinetochore-localized astrin/SPAG5 binding protein (HGNC Symbol)