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A majority of malignant cells showed moderate cytoplasmic immunoreactivity. Many liver, testicular and colorectal cancers along with a few gastric and pancreatic cancers were strongly stained. Most malignant gliomas were weakly stained or negative.
GENE INFORMATION
Gene name
RTN4IP1 (HGNC Symbol)
Synonyms
NIMP
Description
Reticulon 4 interacting protein 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a novel mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. The interaction of reticulon 4 with mitochondrial proteins may provide insight into the mechanisms for reticulon-induced inhibition of neurite growth. [provided by RefSeq, Jul 2008]