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Group enriched (appendix, lymph node, spleen, tonsil)
Protein evidence
Evidence at protein level
ANTIBODY IHC RELIABILITY
Reliability score
Pending cancer tissue analysis.
PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed
PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY
GENE INFORMATION
Gene name
FCRL2 (HGNC Symbol)
Synonyms
CD307b, FCRH2, IRTA4, SPAP1
Description
Fc receptor-like 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]