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PATHOLOGY ATLAS CERVICAL CANCER

GENE/PROTEIN

Antibody validation

Dictionary

Cervical cancer

CERVICAL CANCER - Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival, using best separation (to the left) and median separation (to the right). Patients were divided based on level of expression into one of the two groups "low" or "high". Below each Kaplan-Meier plot, corresponding expression cutoff, 5-year survival for patients with high expression, 5-year survival for patients with low expression and log-rank P value are displayed. For melanoma and glioma, 3-year survival is shown. The survival analysis is described in Assays & Annotation.

The tabs at the top of the survival analysis section can be used to switch between the different cancer subtypes.

Best separation

Median separation

Expression cutoffi

5-year survival for patients with higher expression than the expression cutoff.

80.9 FPKM 170.1 FPKM

5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

68% 71%

5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

59% 62%

Log-rank P valuei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

1.31e-1 6.31e-1

Interactive survival scatter plot (individual patient data)i

The Scatter Survival plot shows the clinical status for all individuals in the patient cohort, based on the same data as in the Kaplan-Meier plots. Living patients are shown in blue and deceased patients in red. The x-axis shows the expression levels (FPKM) of the investigated gene at the time of diagnosis and the y-axis shows the number of years of survival (living years) after the diagnosis.

Individual patient data is displayed in an interactive plot and can be filtered by clicking on one or several category buttons to the left. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be changed to "x linear" by clicking on the "x log" button on the left. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.




Stage:

TCGA RNA samplesi

RNA-seq data is reported as median FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average FPKM

229.5

Number of samples

291

Samples

Sample

Description

FPKM

TCGA-FU-A3YQ-01A 35 years, female, white 1225.7
TCGA-EA-A50E-01A 45 years, female, asian 1104.3
TCGA-MU-A8JM-01A 47 years, female, white 935.9
TCGA-C5-A1BI-01B 31 years, female, white 884.0
TCGA-DS-A3LQ-01A 46 years, female 881.0
TCGA-C5-A901-01A 44 years, female, white 852.5
TCGA-C5-A1M7-01A 37 years, female, white 800.2
TCGA-LP-A4AU-01A 35 years, female, asian 760.4
TCGA-C5-A905-01A 37 years, female, black or african american 753.7
TCGA-ZJ-AAXA-01A 64 years, female, white 722.7
TCGA-Q1-A6DW-01A 44 years, female, white 690.4
TCGA-IR-A3LL-01A 60 years, female, white 671.0
TCGA-EK-A2RE-01A 26 years, female, white 666.3
TCGA-DS-A5RQ-01A 80 years, female, white 663.7
TCGA-C5-A1MK-01A 79 years, female, white 645.3
TCGA-EK-A2PL-01A 36 years, female, white 632.1
TCGA-FU-A3TQ-01A 55 years, female, white 626.8
TCGA-VS-A8EG-01A 36 years, female 617.4
TCGA-ZX-AA5X-01A 64 years, female, white 598.3
TCGA-FU-A3HY-01A 47 years, female, white 593.1
TCGA-UC-A7PG-01A 44 years, female, white 586.2
TCGA-VS-A9UI-01A 76 years, female, white 582.9
TCGA-LP-A7HU-01A 53 years, female, asian 580.2
TCGA-EA-A3HT-01A 68 years, female, white 574.2
TCGA-C5-A7UE-01A 45 years, female, white 561.8
TCGA-ZJ-A8QR-01A 38 years, female, native hawaiian or other pacific islander 554.4
TCGA-VS-A9UU-01A 42 years, female 549.7
TCGA-MU-A51Y-01A 27 years, female, white 548.3
TCGA-VS-A8QF-01A 42 years, female, white 547.3
TCGA-VS-A8EL-01A 38 years, female, black or african american 536.0
TCGA-FU-A3NI-01A 45 years, female, white 528.3
TCGA-VS-A8Q8-01A 26 years, female, white 527.4
TCGA-VS-A9UH-01A 53 years, female, black or african american 513.2
TCGA-JX-A5QV-01A 37 years, female, white 483.7
TCGA-FU-A5XV-01A 32 years, female, white 466.1
TCGA-C5-A1BK-01B 36 years, female, black or african american 463.5
TCGA-DG-A2KL-01A 53 years, female 460.1
TCGA-EK-A2RB-01A 48 years, female, white 459.6
TCGA-ZJ-AAX4-01A 85 years, female, white 455.8
TCGA-EA-A5O9-01A 39 years, female, white 455.4
TCGA-DS-A0VN-01A 47 years, female, white 441.2
TCGA-Q1-A6DV-01A 36 years, female, asian 436.8
TCGA-VS-A9UV-01A 74 years, female 417.0
TCGA-C5-A7CG-01A 55 years, female, white 410.7
TCGA-EK-A2RN-01A 45 years, female, white 410.1
TCGA-VS-A94Z-01A 38 years, female, white 408.1
TCGA-MA-AA3Y-01A 48 years, female, white 400.0
TCGA-FU-A3WB-01A 43 years, female, white 391.2
TCGA-MY-A5BF-01A 68 years, female, white 389.7
TCGA-C5-A1BM-01A 78 years, female, black or african american 387.1
TCGA-EX-A449-01A 42 years, female, white 383.5
TCGA-JW-AAVH-01A 46 years, female, white 372.7
TCGA-DS-A1OA-01A 77 years, female, asian 370.6
TCGA-VS-A9U5-01A 57 years, female, white 370.5
TCGA-Q1-A6DT-01A 55 years, female, white 364.6
TCGA-C5-A1BJ-01A 34 years, female, white 361.9
TCGA-C5-A2M1-01A 37 years, female, white 359.5
TCGA-Q1-A5R1-01A 32 years, female, white 351.4
TCGA-C5-A7CH-01A 43 years, female, white 350.6
TCGA-C5-A1M8-01A 43 years, female, white 350.1
TCGA-C5-A7UC-01A 48 years, female, white 348.0
TCGA-FU-A770-01A 33 years, female, white 344.3
TCGA-IR-A3LB-01A 53 years, female, white 333.2
TCGA-DS-A1OB-01A 45 years, female, white 331.0
TCGA-VS-A9UY-01A 29 years, female 331.0
TCGA-C5-A3HL-01A 76 years, female, white 327.6
TCGA-UC-A7PD-01A 21 years, female, american indian or alaska native 326.4
TCGA-EK-A2RA-01A 74 years, female 325.5
TCGA-EK-A2H1-01A 20 years, female, white 320.6
TCGA-LP-A5U3-01A 40 years, female, asian 315.6
TCGA-EA-A5ZD-01A 40 years, female, asian 315.0
TCGA-MA-AA3Z-01A 43 years, female, white 313.8
TCGA-R2-A69V-01A 42 years, female, white 308.7
TCGA-VS-A9UQ-01A 32 years, female 306.7
TCGA-IR-A3LA-01A 60 years, female, white 304.5
TCGA-C5-A7CO-01A 68 years, female, white 299.5
TCGA-EX-A1H6-01B 38 years, female, white 298.9
TCGA-EK-A2IP-01A 28 years, female, white 295.8
TCGA-VS-A9UJ-01A 55 years, female 291.8
TCGA-C5-A2LZ-01A 65 years, female, white 288.8
TCGA-MA-AA3X-01A 50 years, female, black or african american 277.9
TCGA-JX-A3Q0-01A 63 years, female, black or african american 273.9
TCGA-MA-AA43-01A 48 years, female, white 272.6
TCGA-VS-A953-01A 63 years, female 271.1
TCGA-VS-A8QM-01A 47 years, female 271.0
TCGA-EK-A2IR-01A 48 years, female, white 269.7
TCGA-EA-A97N-01A 38 years, female, white 267.8
TCGA-EK-A2RM-01A 40 years, female, white 264.1
TCGA-EA-A3QE-01A 45 years, female, white 258.3
TCGA-C5-A2LV-01A 36 years, female, black or african american 253.7
TCGA-VS-A94Y-01A 47 years, female, white 252.6
TCGA-MA-AA42-01A 75 years, female, white 247.0
TCGA-JX-A3Q8-01A 40 years, female, asian 245.8
TCGA-EK-A2RO-01A 59 years, female, american indian or alaska native 234.5
TCGA-VS-A8QC-01A 51 years, female, white 233.3
TCGA-Q1-A73O-01A 37 years, female 229.7
TCGA-VS-A957-01A 64 years, female, white 229.5
TCGA-C5-A7CK-01A 58 years, female, white 225.8
TCGA-C5-A3HF-01A 24 years, female, white 220.5
TCGA-EA-A5FO-01A 59 years, female, white 220.0
TCGA-DR-A0ZL-01A 53 years, female, asian 218.0
TCGA-C5-A0TN-01A 21 years, female, black or african american 217.3
TCGA-C5-A7UH-01A 55 years, female, white 217.2
TCGA-LP-A4AX-01A 45 years, female, asian 213.0
TCGA-C5-A7CJ-01A 42 years, female, white 212.2
TCGA-EX-A1H5-01A 58 years, female, black or african american 210.6
TCGA-C5-A7X5-01A 72 years, female, black or african american 210.2
TCGA-JW-A5VG-01A 35 years, female, american indian or alaska native 209.6
TCGA-EA-A3HR-01A 57 years, female, white 209.6
TCGA-MY-A5BD-01A 62 years, female, white 208.7
TCGA-C5-A1ML-01A 49 years, female, white 208.2
TCGA-EK-A2H0-01A 24 years, female, white 207.4
TCGA-C5-A2LS-01A 37 years, female, white 206.8
TCGA-EA-A1QT-01A 47 years, female, white 205.1
TCGA-EA-A3QD-01A 59 years, female, white 204.5
TCGA-4J-AA1J-01A 31 years, female, white 204.2
TCGA-WL-A834-01A female, white 201.2
TCGA-EX-A69L-01A 41 years, female, asian 200.1
TCGA-EK-A3GK-01A 33 years, female, white 198.7
TCGA-FU-A2QG-01A 29 years, female, white 198.6
TCGA-C5-A2LT-01A 38 years, female, white 196.4
TCGA-C5-A1BQ-01C 65 years, female, white 196.1
TCGA-VS-A950-01A 42 years, female 195.6
TCGA-EK-A2PM-01A 81 years, female, white 194.3
TCGA-EA-A411-01A 50 years, female, white 194.1
TCGA-C5-A1M5-01A 53 years, female, white 193.4
TCGA-XS-A8TJ-01A 41 years, female, black or african american 192.9
TCGA-FU-A40J-01A 38 years, female, white 189.1
TCGA-C5-A1BE-01B 65 years, female, white 188.9
TCGA-EK-A3GJ-01A 51 years, female, native hawaiian or other pacific islander 188.3
TCGA-EA-A44S-01A 31 years, female, white 185.7
TCGA-VS-A9UM-01A 39 years, female, black or african american 184.6
TCGA-VS-A8EK-01A 65 years, female, white 184.2
TCGA-VS-A9UB-01A 54 years, female 183.5
TCGA-EA-A78R-01A 54 years, female, asian 183.4
TCGA-MY-A913-01A 28 years, female, black or african american 182.5
TCGA-IR-A3LC-01A 40 years, female, white 181.1
TCGA-EK-A2PG-01A 89 years, female, black or african american 180.9
TCGA-VS-A9V5-01A 50 years, female, white 180.8
TCGA-LP-A4AW-01A 52 years, female, asian 179.7
TCGA-Q1-A5R2-01A 64 years, female, white 177.7
TCGA-GH-A9DA-01A 27 years, female, white 177.4
TCGA-EK-A2RC-01A 33 years, female 174.7
TCGA-C5-A8ZZ-01A 41 years, female, white 170.8
TCGA-DS-A0VM-01A 51 years, female, white 170.2
TCGA-Q1-A73R-01A 45 years, female, white 170.1
TCGA-BI-A0VR-01A 53 years, female, white 169.5
TCGA-C5-A2M2-01A 56 years, female, white 169.2
TCGA-C5-A1MN-01A 42 years, female, white 168.9
TCGA-ZJ-A8QQ-01A 24 years, female, white 166.0
TCGA-FU-A23L-01A 60 years, female, white 165.7
TCGA-C5-A1MH-01A 71 years, female, white 165.0
TCGA-EX-A3L1-01A 32 years, female, white 165.0
TCGA-ZJ-AAXU-01A 51 years, female, white 164.2
TCGA-JW-A5VK-01A 43 years, female, black or african american 161.8
TCGA-C5-A1BN-01B 26 years, female, white 161.0
TCGA-VS-A94X-01A 40 years, female, black or african american 159.1
TCGA-IR-A3LI-01A 48 years, female, white 156.4
TCGA-EA-A3HQ-01A 60 years, female, white 155.6
TCGA-DG-A2KH-01A 25 years, female 150.8
TCGA-VS-A9UC-01A 32 years, female 150.2
TCGA-HG-A2PA-01A 38 years, female, white 149.9
TCGA-C5-A1M9-01A 46 years, female, white 149.1
TCGA-DG-A2KK-01A 51 years, female 148.2
TCGA-C5-A7CL-01A 48 years, female, white 147.8
TCGA-MU-A5YI-01A 60 years, female, black or african american 143.7
TCGA-EK-A2R7-01A 45 years, female, white 143.4
TCGA-EK-A2RK-01A 67 years, female, white 143.2
TCGA-IR-A3LH-01A 49 years, female, black or african american 141.1
TCGA-EA-A3Y4-01A 40 years, female, white 141.0
TCGA-C5-A1BL-01A 32 years, female, white 141.0
TCGA-EA-A3HU-01A 43 years, female, white 140.5
TCGA-2W-A8YY-01A 51 years, female, white 140.1
TCGA-DS-A7WH-01A 34 years, female, white 139.5
TCGA-JW-A5VI-01A 45 years, female, american indian or alaska native 138.4
TCGA-DR-A0ZM-01A 61 years, female, white 137.1
TCGA-C5-A8XK-01A 30 years, female, black or african american 136.7
TCGA-DS-A1OC-01A 47 years, female, white 135.5
TCGA-Q1-A73S-01A 33 years, female, white 135.3
TCGA-VS-A9V3-01A 62 years, female, white 134.9
TCGA-EK-A2GZ-01A 64 years, female, black or african american 133.3
TCGA-DS-A7WI-01A 43 years, female, white 128.7
TCGA-DS-A0VL-01A 25 years, female, white 127.9
TCGA-BI-A20A-01A 49 years, female, white 125.2
TCGA-DS-A0VK-01A 46 years, female, white 124.2
TCGA-C5-A7UI-01A 42 years, female, black or african american 123.7
TCGA-HM-A4S6-01A 51 years, female, white 123.6
TCGA-VS-A9U7-01A 30 years, female, white 122.8
TCGA-EK-A2RL-01A 33 years, female, black or african american 120.5
TCGA-JW-A5VL-01A 37 years, female, american indian or alaska native 119.1
TCGA-C5-A7X3-01A 70 years, female, white 115.0
TCGA-Q1-A5R3-01A 56 years, female, white 114.3
TCGA-IR-A3LF-01A 64 years, female, white 113.9
TCGA-EK-A2R8-01A 48 years, female, white 112.6
TCGA-EA-A43B-01A 43 years, female, white 112.5
TCGA-DS-A1OD-01A 49 years, female, white 112.3
TCGA-C5-A8XI-01A 69 years, female, black or african american 112.2
TCGA-RA-A741-01A 34 years, female, white 111.4
TCGA-DS-A1O9-01A 75 years, female, white 110.9
TCGA-C5-A3HD-01B 51 years, female, white 109.6
TCGA-JX-A3PZ-01A 25 years, female, white 108.6
TCGA-C5-A7XC-01A 26 years, female, white 108.0
TCGA-UC-A7PI-01A 45 years, female, white 107.9
TCGA-DG-A2KM-01A 46 years, female 107.8
TCGA-EK-A2RJ-01A 51 years, female, white 106.9
TCGA-HM-A3JK-01A 64 years, female, white 106.3
TCGA-HM-A3JJ-01A 40 years, female, black or african american 105.1
TCGA-EK-A2PK-01A 43 years, female, white 103.4
TCGA-FU-A3EO-01A 55 years, female, white 103.4
TCGA-VS-A958-01A 46 years, female, white 102.6
TCGA-C5-A1ME-01A 41 years, female, white 102.2
TCGA-EA-A6QX-01A 49 years, female, asian 101.0
TCGA-VS-A8EC-01A 55 years, female, white 100.9
TCGA-IR-A3L7-01A 37 years, female, white 99.7
TCGA-VS-A8QA-01A 44 years, female 99.5
TCGA-EA-A4BA-01A 49 years, female, white 99.0
TCGA-C5-A8YR-01A 56 years, female, white 99.0
TCGA-VS-A8EH-01A 56 years, female 97.4
TCGA-VS-A8EI-01A 38 years, female, white 96.9
TCGA-EA-A1QS-01A 46 years, female, white 96.2
TCGA-JW-A5VJ-01A 56 years, female, american indian or alaska native 92.2
TCGA-C5-A8XH-01A 39 years, female, white 88.5
TCGA-Q1-A73P-01A 45 years, female, white 87.4
TCGA-EA-A3HS-01A 35 years, female, white 86.6
TCGA-VS-A9UR-01A 53 years, female, white 84.4
TCGA-EA-A5ZF-01A 56 years, female, asian 82.7
TCGA-C5-A7X8-01A 35 years, female, white 81.2
TCGA-VS-AA62-01A 51 years, female, white 80.6
TCGA-C5-A907-01A 47 years, female, white 79.1
TCGA-EA-A439-01A 50 years, female, asian 79.1
TCGA-IR-A3LK-01A 69 years, female, white 78.7
TCGA-C5-A7CM-01A 35 years, female, white 76.5
TCGA-VS-A9UZ-01A 61 years, female, white 75.3
TCGA-MA-AA3W-01A 54 years, female, white 75.3
TCGA-DS-A7WF-01A 41 years, female 74.4
TCGA-C5-A1BF-01B 46 years, female, white 72.0
TCGA-BI-A0VS-01A 48 years, female, white 71.1
TCGA-VS-A954-01A 67 years, female 68.1
TCGA-VS-A959-01A 76 years, female 67.7
TCGA-LP-A5U2-01A 30 years, female, asian 66.7
TCGA-FU-A57G-01A 49 years, female, white 66.2
TCGA-JW-A852-01A 42 years, female, white 65.5
TCGA-C5-A1MQ-01A 35 years, female, white 64.6
TCGA-C5-A8XJ-01A 74 years, female, white 63.5
TCGA-C5-A8YQ-01A 79 years, female, white 62.1
TCGA-Q1-A73Q-01A 46 years, female, white 58.5
TCGA-UC-A7PF-01A 44 years, female 58.3
TCGA-EK-A2R9-01A 58 years, female, white 57.9
TCGA-FU-A3HZ-01A 64 years, female, white 56.5
TCGA-C5-A8YT-01A 36 years, female, white 54.3
TCGA-VS-A9V2-01A 29 years, female, white 52.5
TCGA-MA-AA41-01A 33 years, female, white 52.3
TCGA-C5-A1MJ-01A 61 years, female, white 52.3
TCGA-C5-A1MI-01A 50 years, female, white 50.9
TCGA-MY-A5BE-01A 42 years, female, black or african american 50.9
TCGA-C5-A3HE-01A 44 years, female, white 49.6
TCGA-EK-A2PI-01A 44 years, female, white 48.3
TCGA-C5-A2LX-01A 54 years, female, white 48.3
TCGA-VS-A9UD-01A 73 years, female, white 48.3
TCGA-VS-A8EB-01A 41 years, female, white 47.5
TCGA-C5-A1MP-01A 34 years, female, black or african american 45.0
TCGA-EX-A69M-01A 62 years, female, white 43.9
TCGA-EX-A8YF-01A 44 years, female, white 43.8
TCGA-VS-A94W-01A 39 years, female, white 43.7
TCGA-VS-A8EJ-01A 60 years, female, white 42.0
TCGA-VS-A8Q9-01A 79 years, female, white 40.1
TCGA-EA-A556-01A 38 years, female, white 38.1
TCGA-FU-A3TX-01A 78 years, female 37.2
TCGA-EK-A3GN-01A 47 years, female, white 36.4
TCGA-VS-A9U6-01A 52 years, female, white 34.4
TCGA-VS-A9UP-01A 43 years, female 32.4
TCGA-C5-A2LY-01A 30 years, female, white 31.6
TCGA-VS-A952-01A 66 years, female, white 31.3
TCGA-EA-A5ZE-01A 54 years, female, asian 30.4
TCGA-C5-A1M6-01A 55 years, female, white 28.1
TCGA-FU-A23K-01A 28 years, female, white 27.0
TCGA-VS-A9UL-01A 79 years, female, white 23.3
TCGA-C5-A902-01A 35 years, female, black or african american 23.0
TCGA-VS-A9V1-01A 46 years, female, white 21.9
TCGA-JW-A69B-01A 44 years, female, white 20.5
TCGA-PN-A8MA-01A 43 years, female, black or african american 18.3
TCGA-JW-A5VH-01A 53 years, female, american indian or alaska native 16.4
TCGA-VS-A9UT-01A 72 years, female, asian 14.4
TCGA-EA-A410-01A 51 years, female, white 14.1
TCGA-C5-A1MF-01A 49 years, female, white 11.8
TCGA-HM-A6W2-01A 35 years, female, black or african american 8.7
TCGA-VS-A8QH-01A 76 years, female, white 8.6
TCGA-VS-A9V0-01A 58 years, female 8.6
TCGA-VS-A9V4-01A 63 years, female, white 7.1
TCGA-VS-A9UO-01A 43 years, female, white 3.5
TCGA-DG-A2KJ-01A 50 years, female 3.2
Show all

CERVICAL CANCER - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

HPA011271

HPA011272

CAB013023

CAB035987

CAB058693

 Antibody staining
  High
  Medium
  Low
  Not detected
      
 Intensity
  Strong
  Moderate
  Weak
  Negative
      
 Quantity
  >75%
  75%-25%
  <25%
  Rare
  Negative
      
 Location
  Cytoplasmic/membranous,nuclear
  Cytoplasmic/membranous
  Nuclear
  None
      

Click images for details








































































































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