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PATHOLOGY ATLAS GLIOMA

GENE/PROTEIN

Antibody validation

Dictionary

Glioma

GLIOMA - Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival, using best separation (to the left) and median separation (to the right). Patients were divided based on level of expression into one of the two groups "low" or "high". Below each Kaplan-Meier plot, corresponding expression cutoff, 5-year survival for patients with high expression, 5-year survival for patients with low expression and log-rank P value are displayed. For melanoma and glioma, 3-year survival is shown. The survival analysis is described in Assays & Annotation.

The tabs at the top of the survival analysis section can be used to switch between the different cancer subtypes.

Best separation

Median separation

Expression cutoffi

5-year survival for patients with higher expression than the expression cutoff.

91.5 FPKM 68.5 FPKM

3-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

0% 3%

3-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

9% 10%

Log-rank P valuei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

1.03e-2 6.57e-2

Interactive survival scatter plot (individual patient data)i

The Scatter Survival plot shows the clinical status for all individuals in the patient cohort, based on the same data as in the Kaplan-Meier plots. Living patients are shown in blue and deceased patients in red. The x-axis shows the expression levels (FPKM) of the investigated gene at the time of diagnosis and the y-axis shows the number of years of survival (living years) after the diagnosis.

Individual patient data is displayed in an interactive plot and can be filtered by clicking on one or several category buttons to the left. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be changed to "x linear" by clicking on the "x log" button on the left. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.




Stage:

TCGA RNA samplesi

RNA-seq data is reported as median FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average FPKM

77.8

Number of samples

153

Samples

Sample

Description

FPKM

TCGA-14-1829-01A 57 years, male, black or african american 277.2
TCGA-28-5213-01A 72 years, male, white 262.5
TCGA-12-5299-01A 56 years, female, white 237.9
TCGA-26-5136-01B 78 years, female, white 230.2
TCGA-06-5856-01A 58 years, male, white 205.1
TCGA-19-1787-01B 49 years, male, white 201.2
TCGA-14-1823-01A 58 years, female, white 192.5
TCGA-32-2616-01A 48 years, female, white 184.7
TCGA-27-1832-01A 59 years, female, white 181.3
TCGA-02-2486-01A 64 years, male, white 178.6
TCGA-28-2509-01A 77 years, female, white 173.2
TCGA-41-4097-01A 63 years, female, white 154.8
TCGA-19-4065-01A 36 years, male, white 154.6
TCGA-28-2499-01A 59 years, male, white 149.7
TCGA-06-5859-01A 63 years, male, white 149.5
TCGA-32-2615-01A 62 years, male, white 149.2
TCGA-14-2554-01A 52 years, female, white 146.9
TCGA-26-5132-01A 74 years, male, white 145.4
TCGA-06-0750-01A 43 years, male, white 145.2
TCGA-27-1831-01A 66 years, male, white 144.7
TCGA-02-0055-01A 62 years, female, white 143.5
TCGA-06-0882-01A 30 years, male, white 142.0
TCGA-27-2526-01A 79 years, female, white 139.3
TCGA-06-0644-01A 71 years, male, black or african american 133.6
TCGA-26-5139-01A 65 years, female, white 133.4
TCGA-27-1834-01A 56 years, male, white 132.9
TCGA-06-5410-01A 72 years, female, white 124.2
TCGA-14-0817-01A 69 years, female, white 121.0
TCGA-06-2562-01A 81 years, male, white 120.3
TCGA-06-0187-01A 69 years, male, white 119.9
TCGA-76-4925-01A 76 years, male, white 118.2
TCGA-76-4926-01B 68 years, male, white 117.7
TCGA-14-0781-01B 49 years, male, black or african american 117.5
TCGA-06-0747-01A 53 years, male, white 114.9
TCGA-19-2625-01A 76 years, female, white 107.3
TCGA-06-0130-01A 54 years, male, white 106.7
TCGA-19-5960-01A 56 years, male, white 105.9
TCGA-27-2519-01A 48 years, male, white 104.7
TCGA-06-5858-01A 45 years, female, white 104.4
TCGA-06-5413-01A 67 years, male, white 103.9
TCGA-14-1034-01A 60 years, female 103.8
TCGA-76-4929-01A 76 years, female, white 103.8
TCGA-12-5295-01A 60 years, female, white 102.7
TCGA-06-0878-01A 74 years, male, white 101.4
TCGA-06-0219-01A 67 years, male, white 100.1
TCGA-19-2620-01A 70 years, male, white 98.0
TCGA-06-0190-01A 62 years, male, white 96.3
TCGA-06-0139-01A 40 years, male, white 94.8
TCGA-32-1982-01A 76 years, female, white 93.5
TCGA-06-0649-01B 73 years, female, black or african american 91.9
TCGA-06-0743-01A 69 years, male, white 91.1
TCGA-06-2561-01A 53 years, female, white 90.7
TCGA-06-0125-01A 63 years, female, white 89.2
TCGA-27-2528-01A 62 years, male, white 88.5
TCGA-15-0742-01A 65 years, male, white 87.6
TCGA-06-5408-01A 54 years, female, white 86.7
TCGA-28-2513-01A 69 years, female, white 85.8
TCGA-28-5209-01A 66 years, female, white 85.4
TCGA-06-0141-01A 62 years, male, white 85.4
TCGA-14-0789-01A 54 years, male, white 85.1
TCGA-16-1045-01B 49 years, female, white 85.0
TCGA-28-5216-01A 52 years, male, white 82.1
TCGA-06-5418-01A 75 years, female, white 81.7
TCGA-41-3915-01A 48 years, male, white 81.2
TCGA-27-1830-01A 57 years, male, white 81.1
TCGA-28-5204-01A 72 years, male, white 80.7
TCGA-28-5207-01A 71 years, male, white 79.0
TCGA-76-4928-01B 85 years, female, white 78.3
TCGA-28-5208-01A 52 years, male, white 78.1
TCGA-06-1804-01A 81 years, female, white 77.4
TCGA-76-4927-01A 58 years, male, white 76.7
TCGA-06-0158-01A 73 years, male, white 75.1
TCGA-06-5414-01A 61 years, male, white 73.2
TCGA-19-2619-01A 55 years, female, black or african american 72.7
TCGA-27-1835-01A 53 years, female, white 72.4
TCGA-02-2485-01A 53 years, male, black or african american 71.2
TCGA-32-2638-01A 67 years, male, white 68.5
TCGA-19-2629-01A 60 years, male, white 68.1
TCGA-06-0184-01A 63 years, male, white 68.0
TCGA-27-2524-01A 56 years, male, white 67.6
TCGA-06-0645-01A 56 years, female, white 66.6
TCGA-06-0138-01A 43 years, male, white 66.5
TCGA-06-0168-01A 59 years, female, white 65.9
TCGA-28-5215-01A 62 years, female, white 64.4
TCGA-12-0619-01A 60 years, male, white 64.2
TCGA-06-0744-01A 67 years, male, white 63.8
TCGA-14-0787-01A 69 years, male, asian 63.4
TCGA-06-2565-01A 59 years, male, asian 62.4
TCGA-32-1980-01A 72 years, male, white 56.8
TCGA-06-2567-01A 65 years, male, white 56.8
TCGA-06-2564-01A 50 years, male, white 56.4
TCGA-08-0386-01A 74 years, male, white 55.7
TCGA-06-2559-01A 83 years, male, white 54.8
TCGA-76-4932-01A 50 years, female, white 54.2
TCGA-16-0846-01A 85 years, male, white 53.7
TCGA-06-0156-01A 57 years, male, white 51.7
TCGA-28-1747-01C 44 years, male, white 51.4
TCGA-32-5222-01A 66 years, male, white 51.1
TCGA-32-2632-01A 80 years, male, white 47.5
TCGA-28-1753-01A 53 years, male, white 47.3
TCGA-12-0616-01A 36 years, female, white 46.6
TCGA-06-0646-01A 61 years, male, white 45.1
TCGA-32-2634-01A 82 years, male, white 43.2
TCGA-76-4931-01A 70 years, female, white 42.1
TCGA-06-0211-01B 47 years, male, white 41.3
TCGA-06-0210-01A 72 years, female, white 40.0
TCGA-14-0790-01B 64 years, female, white 38.5
TCGA-06-5412-01A 78 years, female, white 38.2
TCGA-06-0749-01A 50 years, male, black or african american 37.7
TCGA-26-5134-01A 74 years, male, white 37.4
TCGA-06-0157-01A 63 years, female, white 36.5
TCGA-12-0821-01A 62 years, male, white 36.5
TCGA-32-4213-01A 47 years, female, white 31.9
TCGA-06-0178-01A 39 years, male, white 30.0
TCGA-32-1970-01A 59 years, male, white 30.0
TCGA-28-5218-01A 63 years, male, white 30.0
TCGA-02-2483-01A 43 years, male, asian 29.4
TCGA-02-0047-01A 78 years, male, white 28.9
TCGA-06-2563-01A 72 years, female, white 27.2
TCGA-28-5220-01A 67 years, male, white 27.1
TCGA-06-5411-01A 51 years, male, white 27.0
TCGA-28-2514-01A 45 years, male, asian 26.2
TCGA-06-0745-01A 59 years, male, white 25.8
TCGA-06-2558-01A 75 years, female, white 24.8
TCGA-06-0238-01A 46 years, male, white 24.5
TCGA-27-2523-01A 63 years, male, white 24.2
TCGA-41-2572-01A 67 years, male, white 24.0
TCGA-06-0132-01A 49 years, male, white 23.6
TCGA-27-1837-01A 36 years, male, white 23.2
TCGA-14-0871-01A 75 years, female, white 22.6
TCGA-12-3653-01A 34 years, female, white 22.3
TCGA-26-5135-01A 72 years, female, white 22.2
TCGA-06-0686-01A 53 years, male, white 22.1
TCGA-06-5416-01A 23 years, female, white 21.8
TCGA-19-2624-01A 51 years, male, white 20.7
TCGA-06-2557-01A 76 years, male, black or african american 20.6
TCGA-12-3650-01A 46 years, male, white 19.3
TCGA-06-0174-01A 54 years, male, white 18.6
TCGA-26-5133-01A 59 years, male, white 16.7
TCGA-41-2571-01A 89 years, male, white 16.1
TCGA-14-1825-01A 70 years, male, white 15.6
TCGA-12-1597-01B 62 years, female, white 15.6
TCGA-15-1444-01A 21 years, male, white 15.1
TCGA-06-5417-01A 45 years, female, white 14.3
TCGA-06-2570-01A 21 years, female, white 13.8
TCGA-06-2569-01A 24 years, female, black or african american 12.2
TCGA-41-5651-01A 59 years, female, black or african american 11.7
TCGA-12-3652-01A 60 years, male, white 10.9
TCGA-12-0618-01A 49 years, male, white 9.0
TCGA-27-2521-01A 34 years, male, white 7.7
TCGA-26-1442-01A 43 years, male, white 6.3
TCGA-19-1390-01A 63 years, female, white 5.8
TCGA-06-0129-01A 30 years, male, asian 4.4
Show all

GLIOMA - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

HPA011271

HPA011272

CAB013023

CAB035987

CAB058693

 Antibody staining
  High
  Medium
  Low
  Not detected
      
 Intensity
  Strong
  Moderate
  Weak
  Negative
      
 Quantity
  >75%
  75%-25%
  <25%
  Rare
  Negative
      
 Location
  Cytoplasmic/membranous,nuclear
  Cytoplasmic/membranous
  Nuclear
  None
      

Click images for details











































































































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