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PATHOLOGY ATLAS PANCREATIC CANCER

GENE/PROTEIN

Antibody validation

Dictionary

Pancreatic cancer

PANCREATIC CANCER - Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival, using best separation (to the left) and median separation (to the right). Patients were divided based on level of expression into one of the two groups "low" or "high". Below each Kaplan-Meier plot, corresponding expression cutoff, 5-year survival for patients with high expression, 5-year survival for patients with low expression and log-rank P value are displayed. For melanoma and glioma, 3-year survival is shown. The survival analysis is described in Assays & Annotation.

The tabs at the top of the survival analysis section can be used to switch between the different cancer subtypes.

Best separation

Median separation

Expression cutoffi

5-year survival for patients with higher expression than the expression cutoff.

35.9 FPKM 65.6 FPKM

5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

18% 19%

5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

56% 35%

Log-rank P valuei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

2.54e-3 1.62e-2

Interactive survival scatter plot (individual patient data)i

The Scatter Survival plot shows the clinical status for all individuals in the patient cohort, based on the same data as in the Kaplan-Meier plots. Living patients are shown in blue and deceased patients in red. The x-axis shows the expression levels (FPKM) of the investigated gene at the time of diagnosis and the y-axis shows the number of years of survival (living years) after the diagnosis.

Individual patient data is displayed in an interactive plot and can be filtered by clicking on one or several category buttons to the left. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be changed to "x linear" by clicking on the "x log" button on the left. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.




Stage:

TCGA RNA samplesi

RNA-seq data is reported as median FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average FPKM

76.8

Number of samples

176

Samples

Sample

Description

FPKM

TCGA-L1-A7W4-01A 48 years, female, white, stage:iib 580.0
TCGA-IB-7646-01A 60 years, male, white, stage:iib 315.7
TCGA-IB-A5SS-01A 64 years, female, white, stage:iib 259.7
TCGA-FB-AAQ2-01A 81 years, female, white, stage:iib 236.9
TCGA-3A-A9IU-01A 65 years, male, white, stage:iib 204.3
TCGA-2J-AAB6-01A 75 years, male, white, stage:iia 195.4
TCGA-2J-AABU-01A 56 years, male, white, stage:iib 190.6
TCGA-IB-A5SQ-01A 56 years, female, white, stage:ib 180.3
TCGA-PZ-A5RE-01A 44 years, female, white, stage:iib 173.3
TCGA-3A-A9IZ-01A 47 years, male, white, stage:iib 173.3
TCGA-FB-A5VM-01A 74 years, male, white, stage:ib 172.7
TCGA-HV-A5A6-01A 65 years, female, asian, stage:iib 166.6
TCGA-FB-AAPZ-01A 54 years, male, white, stage:iib 163.3
TCGA-IB-7885-01A 78 years, female, white, stage:iib 162.9
TCGA-IB-A7M4-01A 81 years, male, white, stage:iib 154.5
TCGA-IB-A6UF-01A 63 years, male, white, stage:iib 151.2
TCGA-IB-A7LX-01A 57 years, male, white, stage:iib 148.5
TCGA-M8-A5N4-01A 48 years, female, stage:iia 147.5
TCGA-HZ-7289-01A 77 years, male, white, stage:iib 141.7
TCGA-XN-A8T3-01A 67 years, male, white, stage:ib 139.9
TCGA-H6-8124-01A 56 years, female, white, stage:iib 134.6
TCGA-HZ-A49I-01A 77 years, male, white, stage:iib 133.8
TCGA-FB-A545-01A 72 years, female, white, stage:iib 130.8
TCGA-HZ-8001-01A 69 years, male, white, stage:iii 125.8
TCGA-HZ-8005-01A 81 years, male, white, stage:iib 125.1
TCGA-2J-AABR-01A 60 years, female, white, stage:iia 124.3
TCGA-2J-AABI-01A 55 years, female, white, stage:iia 118.1
TCGA-F2-6879-01A 57 years, male, white, stage:iib 115.2
TCGA-F2-A8YN-01A 76 years, male, white, stage:iia 114.6
TCGA-3A-A9IH-01A 66 years, female, white, stage:ia 114.2
TCGA-FB-A7DR-01A 48 years, male, asian, stage:iia 112.1
TCGA-IB-7890-01A 73 years, male, stage:ib 110.9
TCGA-IB-7652-01A 49 years, female, asian, stage:iib 109.2
TCGA-HZ-8636-01A 58 years, female, white, stage:iv 107.6
TCGA-F2-A7TX-01A 77 years, male, white, stage:iib 106.5
TCGA-HZ-A9TJ-01A 70 years, male, white, stage:iv 106.4
TCGA-HV-AA8V-01A 50 years, male, asian, stage:iib 105.2
TCGA-IB-7893-01A 64 years, male, white, stage:iia 103.7
TCGA-IB-AAUN-01A 74 years, female, white, stage:ib 102.5
TCGA-HZ-7919-01A 52 years, female, white, stage:iib 101.8
TCGA-2J-AAB4-01A 48 years, male, white, stage:iib 101.8
TCGA-XN-A8T5-01A 53 years, female, white, stage:ib 101.7
TCGA-HZ-A77Q-01A 55 years, female, white, stage:iib 101.4
TCGA-3A-A9IB-01A 69 years, female, white, stage:iib 101.3
TCGA-IB-A5SO-01A 71 years, male, white, stage:iib 100.5
TCGA-FB-A4P5-01A 69 years, female, white, stage:iib 99.3
TCGA-2L-AAQE-01A 56 years, male, white, stage:iib 98.6
TCGA-IB-AAUQ-01A 50 years, male, white, stage:iib 96.7
TCGA-HZ-7920-01A 71 years, male, white, stage:ib 92.6
TCGA-3A-A9IC-01A 61 years, female, white, stage:iib 91.1
TCGA-IB-8127-01A 59 years, male, white, stage:iib 90.1
TCGA-FB-AAQ3-01A 65 years, female, white, stage:iib 88.9
TCGA-IB-7887-01A 62 years, female, white, stage:iib 85.9
TCGA-IB-7889-01A 86 years, female, white, stage:iib 85.1
TCGA-2J-AAB1-01A 65 years, male, white, stage:iib 84.5
TCGA-HV-A5A3-01A 50 years, male, asian, stage:iia 81.7
TCGA-IB-7645-01A 44 years, female, stage:iib 80.9
TCGA-S4-A8RO-01A 75 years, female, white, stage:iib 80.8
TCGA-IB-AAUR-01A 67 years, male, white, stage:iib 80.1
TCGA-Q3-A5QY-01A 58 years, male, white, stage:iib 78.8
TCGA-XD-AAUG-01A 66 years, female, white, stage:iv 77.8
TCGA-HZ-8638-01A 84 years, female, white, stage:ia 77.5
TCGA-XD-AAUL-01A 56 years, male, white, stage:iia 76.8
TCGA-IB-AAUW-01A 63 years, female, white, stage:iib 75.9
TCGA-FB-AAQ1-01A 49 years, male, white, stage:iib 75.8
TCGA-US-A77J-01A 81 years, female, white, stage:iib 75.6
TCGA-S4-A8RP-01A 77 years, female, white, stage:iib 75.3
TCGA-XD-AAUH-01A 57 years, female, white, stage:iib 74.6
TCGA-3A-A9IX-01A 40 years, male, white, stage:ia 73.4
TCGA-2L-AAQJ-01A 49 years, female, white, stage:iii 73.2
TCGA-HZ-8315-01A 54 years, female, white, stage:iia 73.1
TCGA-IB-AAUV-01A 49 years, male, white, stage:iib 72.3
TCGA-2J-AABE-01A 73 years, male, white, stage:iia 71.7
TCGA-2J-AAB8-01A 71 years, male, white, stage:iib 71.6
TCGA-HZ-7923-01A 65 years, male, white, stage:iia 71.6
TCGA-US-A77E-01A 73 years, male, white, stage:iib 71.5
TCGA-IB-7897-01A 54 years, female, white, stage:iib 71.2
TCGA-2J-AABO-01A 43 years, male, white, stage:iib 71.2
TCGA-HZ-A4BH-01A 75 years, male, white, stage:iib 71.1
TCGA-F2-7276-01A 64 years, male, white, stage:iib 71.0
TCGA-HZ-7926-01A 57 years, male, black or african american, stage:iib 70.2
TCGA-IB-AAUO-01A 64 years, female, white, stage:iib 69.8
TCGA-HV-A7OL-01A 70 years, male, asian, stage:iia 69.4
TCGA-F2-7273-01A 54 years, male, black or african american, stage:iib 69.4
TCGA-HZ-A49H-01A 68 years, female, white, stage:iib 67.5
TCGA-2J-AABA-01A 55 years, male, white, stage:iib 67.1
TCGA-3A-A9IJ-01A 65 years, male, white, stage:ib 66.2
TCGA-YH-A8SY-01A 73 years, female, white 66.2
TCGA-HZ-8002-01A 61 years, male, white, stage:iib 65.1
TCGA-YB-A89D-01A 59 years, male, white, stage:iib 65.0
TCGA-HZ-7925-01A 66 years, male, white, stage:iib 64.4
TCGA-IB-AAUS-01A 84 years, female, white, stage:iib 63.6
TCGA-2J-AABP-01A 58 years, female, white, stage:iib 63.6
TCGA-IB-7886-01A 80 years, male, white, stage:iib 62.3
TCGA-FB-AAPS-01A 62 years, female, white, stage:iib 60.7
TCGA-3A-A9I9-01A 67 years, male, white, stage:iia 59.9
TCGA-HZ-7922-01A 61 years, female, white, stage:iib 59.5
TCGA-RL-AAAS-01A 60 years, female, white, stage:ib 58.5
TCGA-HZ-A4BK-01A 72 years, male, white, stage:iib 58.4
TCGA-RB-A7B8-01A 81 years, female, white, stage:iib 57.5
TCGA-3A-A9J0-01A 75 years, male, white, stage:iib 56.1
TCGA-OE-A75W-01A 75 years, male, white, stage:iia 56.0
TCGA-XD-AAUI-01A 50 years, female, white, stage:iib 55.8
TCGA-2J-AAB9-01A 71 years, female, white, stage:iib 55.5
TCGA-F2-A44G-01A 79 years, female, white, stage:iib 55.5
TCGA-US-A774-01A 76 years, female, white, stage:iib 55.0
TCGA-3A-A9I7-01A 45 years, male, black or african american, stage:iib 54.6
TCGA-3E-AAAZ-01A 71 years, male, white, stage:iia 54.0
TCGA-H6-A45N-01A 88 years, female, white, stage:iib 52.8
TCGA-LB-A9Q5-01A 63 years, female, white, stage:iib 52.6
TCGA-IB-A5ST-01A 64 years, female, white, stage:iib 52.4
TCGA-IB-7649-01A 73 years, female, stage:iib 51.9
TCGA-IB-7888-01A 66 years, female, black or african american, stage:iia 49.9
TCGA-HZ-8519-01A 73 years, male, white, stage:ia 48.8
TCGA-2L-AAQI-01A 66 years, male, white, stage:iib 48.6
TCGA-RB-AA9M-01A 43 years, male, white, stage:iib 48.3
TCGA-IB-AAUU-01A 35 years, male, white, stage:iib 47.6
TCGA-3E-AAAY-01A 67 years, male, white, stage:iib 46.5
TCGA-IB-AAUP-01A 68 years, male, white, stage:iib 46.4
TCGA-LB-A7SX-01A 74 years, female, black or african american, stage:iib 46.4
TCGA-HZ-8317-01A 69 years, female, white, stage:iib 46.2
TCGA-US-A77G-01A 64 years, male, white, stage:iib 45.1
TCGA-2J-AABH-01A 61 years, male, white, stage:iia 44.3
TCGA-FB-A4P6-01A 54 years, male, white, stage:iib 44.2
TCGA-Z5-AAPL-01A 74 years, female, white, stage:iia 43.7
TCGA-IB-7651-01A 64 years, female, white, stage:iib 42.9
TCGA-HZ-A49G-01A 58 years, female, white, stage:iib 42.8
TCGA-HV-AA8X-01A 75 years, female, asian, stage:iib 42.6
TCGA-HZ-A77P-01A 77 years, male, white, stage:iib 42.5
TCGA-HV-A5A4-01A 72 years, female, asian, stage:iia 41.6
TCGA-US-A779-01A 54 years, female, white, stage:iib 41.3
TCGA-HV-A5A5-01A 61 years, female, asian, stage:iib 40.0
TCGA-Q3-AA2A-01A 64 years, female, white, stage:ib 39.2
TCGA-IB-7891-01A 49 years, female, white, stage:iib 39.1
TCGA-HZ-A77O-01A 77 years, female, white, stage:iib 38.4
TCGA-IB-A5SP-01A 77 years, male, white, stage:iia 38.3
TCGA-2J-AABF-01A 73 years, male, white, stage:iib 38.2
TCGA-HZ-8637-01A 76 years, female, white, stage:iib 37.8
TCGA-IB-7644-01A 65 years, female, white, stage:iv 37.7
TCGA-FB-AAPY-01A 71 years, male, white, stage:iib 36.4
TCGA-IB-8126-01A 80 years, female, white, stage:iii 35.3
TCGA-2L-AAQL-01A 82 years, male, white, stage:iib 34.6
TCGA-2J-AABK-01A 71 years, male, white, stage:iib 34.2
TCGA-2J-AABT-01A 72 years, female, white, stage:iib 33.4
TCGA-2L-AAQA-01A 76 years, male, white, stage:iib 33.2
TCGA-F2-A44H-01A 65 years, male, white, stage:iia 32.8
TCGA-IB-A6UG-01A 65 years, male, white, stage:iib 32.0
TCGA-HZ-7924-01A 60 years, female, white, stage:iia 31.9
TCGA-H8-A6C1-01A 53 years, male, white, stage:iia 31.1
TCGA-FB-AAQ6-01A 85 years, male, white, stage:ia 29.5
TCGA-IB-AAUT-01A 65 years, male, white, stage:iib 29.4
TCGA-FB-AAPQ-01A 65 years, male, white, stage:iib 28.3
TCGA-YY-A8LH-01A 61 years, female, white, stage:iib 27.8
TCGA-HZ-7918-01A 72 years, male, white, stage:iib 27.6
TCGA-IB-7654-01A 80 years, male, white, stage:iib 25.6
TCGA-3A-A9IN-01A 62 years, female, white, stage:ib 24.1
TCGA-FB-AAQ0-01A 68 years, male, white, stage:iia 23.6
TCGA-HZ-8003-01A 65 years, female, white, stage:iib 23.3
TCGA-FB-AAPU-01A 41 years, female, asian, stage:iia 22.8
TCGA-FB-A78T-01A 71 years, female, white, stage:iib 22.8
TCGA-S4-A8RM-01A 67 years, male, white, stage:iib 20.9
TCGA-IB-AAUM-01A 76 years, male, white, stage:iib 15.6
TCGA-US-A776-01A 61 years, male, white, stage:iia 14.2
TCGA-HZ-A8P1-01A 81 years, male, white, stage:ib 14.0
TCGA-3A-A9I5-01A 58 years, male, white 13.8
TCGA-3A-A9IL-01A 39 years, female, white, stage:i 10.2
TCGA-LB-A8F3-01A 64 years, female, black or african american, stage:iia 9.0
TCGA-3A-A9IV-01A 59 years, female, white, stage:ib 7.9
TCGA-2L-AAQM-01A 52 years, male, white, stage:iib 7.4
TCGA-2J-AABV-01A 74 years, male, white, stage:iib 7.3
TCGA-3A-A9IO-01A 56 years, male, white 7.1
TCGA-3A-A9IR-01A 64 years, female, white, stage:ib 4.0
TCGA-FB-AAPP-01A 71 years, male, white, stage:iib 3.8
TCGA-F2-6880-01A 70 years, male, white, stage:iib 3.6
TCGA-3A-A9IS-01A 67 years, male, white, stage:ib 1.6
TCGA-HV-A7OP-01A 72 years, male, asian, stage:iib 0.9
Show all

PANCREATIC CANCER - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

HPA011271

HPA011272

CAB013023

CAB035987

CAB058693

 Antibody staining
  High
  Medium
  Low
  Not detected
      
 Intensity
  Strong
  Moderate
  Weak
  Negative
      
 Quantity
  >75%
  75%-25%
  <25%
  Rare
  Negative
      
 Location
  Cytoplasmic/membranous,nuclear
  Cytoplasmic/membranous
  Nuclear
  None
      

Click images for details

































































































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