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Majority of cancer tissues showed weak to moderate cytoplasmic positivity. Carcinoid, renal cell carcinomas and thyroid cancers were generally negative.
GENE INFORMATION
Gene name
DTX1 (HGNC Symbol)
Synonyms
hDx-1
Description
Deltex 1, E3 ubiquitin ligase (HGNC Symbol)
Entrez gene summary
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. [provided by RefSeq, Jul 2008]