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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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ABCA10
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

ANTIBODY PRIMARY DATAi

The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.

For histological reference, visit the histological dictionary.

Read more

Antibodies in assay

HPA014535
 

Tissue presentation order  

Organ
Cell type
Alphabetical
 

Tissue

Antibody stainingi

This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

Read more

Annotated protein expressioni

This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.

Read more

HPA014535

h
m
l
n
h
m
l
n
Brain
Cerebral cortex Neuronal cells
Cerebral cortex Endothelial cells
Cerebral cortex Glial cells
Cerebral cortex Neuropil
Hippocampus Neuronal cells
Hippocampus Glial cells
Caudate Neuronal cells
Caudate Glial cells
Cerebellum Purkinje cells
Cerebellum Cells in granular layer
Cerebellum Cells in molecular layer
Endocrine tissues
Thyroid gland Glandular cells
Parathyroid gland Glandular cells
Adrenal gland Glandular cells
Bone marrow & immune system
Appendix Glandular cells
Appendix Lymphoid tissue
Bone marrow Hematopoietic cells
Lymph node Germinal center cells
Lymph node Non-germinal center cells
Tonsil Germinal center cells
Tonsil Non-germinal center cells
Tonsil Squamous epithelial cells
Spleen Cells in white pulp
Spleen Cells in red pulp
Muscle tissues
Heart muscle Myocytes
Skeletal muscle Myocytes
Smooth muscle Smooth muscle cells
Respiratory system
Nasopharynx Respiratory epithelial cells
Bronchus Respiratory epithelial cells
Lung Pneumocytes
Lung Macrophages
Liver & gallbladder
Liver Hepatocytes
Liver Bile duct cells
Gallbladder Glandular cells
Pancreas
Pancreas Exocrine glandular cells
Pancreas Islets of Langerhans
Gastrointestinal tract
Oral mucosa Squamous epithelial cells
Salivary gland Glandular cells
Esophagus Squamous epithelial cells
Stomach 1 Glandular cells
Stomach 2 Glandular cells
Duodenum Glandular cells
Small intestine Glandular cells
Colon Endothelial cells
Colon Glandular cells
Colon Peripheral nerve/ganglion
Rectum Glandular cells
Kidney & urinary bladder
Kidney Cells in glomeruli
Kidney Cells in tubules
Urinary bladder Urothelial cells
Male reproductive system
Testis Cells in seminiferous ducts
Testis Leydig cells
Epididymis Glandular cells
Prostate Glandular cells
Seminal vesicle Glandular cells
Breast and female reproductive system
Breast Adipocytes
Breast Glandular cells
Breast Myoepithelial cells
Vagina Squamous epithelial cells
Cervix, uterine Squamous epithelial cells
Cervix, uterine Glandular cells
Endometrium 1 Glandular cells
Endometrium 1 Cells in endometrial stroma
Endometrium 2 Glandular cells
Endometrium 2 Cells in endometrial stroma
Fallopian tube Glandular cells
Ovary Follicle cells
Ovary Ovarian stroma cells
Placenta Trophoblastic cells
Placenta Decidual cells
Adipose & soft tissue
Soft tissue 1 Adipocytes
Soft tissue 1 Peripheral nerve
Soft tissue 1 Chondrocytes
N/A
Soft tissue 1 Fibroblasts
Soft tissue 2 Adipocytes
Soft tissue 2 Fibroblasts
Soft tissue 2 Chondrocytes
N/A
Soft tissue 2 Peripheral nerve
Skin
Skin 1 Fibroblasts
Skin 1 Keratinocytes
Skin 1 Langerhans
Skin 1 Melanocytes
Skin 2 Epidermal cells
 

Staining summaryi

Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.

Most normal tissues showed weak to moderate cytoplasmic positivity. Basal cells of squamous epithelia, prostate and neuronal cells were strongly stained.
 

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