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Colorectal and urothelial cancers showed moderate cytoplasmic positivity and additional membranous staining in a few cases. Remaining cancer tissues were negative.
Many cases of squamous cell carcinomas, cholangiocarcinomas, colorectal, pancreatic and urothelial cancers along with a few cases of ovarian, endometrial and gastric cancers expressed moderate to strong cytoplasmic/membranous immunoreactivity. Remaining malignant cells were either negative or weakly stained
GENE INFORMATION
Gene name
LAD1
Synonyms
Description
Ladinin 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene may be an anchoring filament that is a component of basement membranes. It may contribute to the stability of the association of the epithelial layers with the underlying mesenchyme. [provided by RefSeq, Jul 2008]