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Tissue enhanced (gallbladder, liver, small intestine)
GTEx:
Tissue enhanced (liver)
FANTOM5:
Tissue enriched (liver)
Protein evidence
Evidence at protein level
Protein expression
Cytoplasmic expression mainly in liver, gallbladder, small intestines and kidney.
DATA RELIABILITY
Data reliability description
Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
RNA tissue category: Tissue enhanced (gallbladder, liver, small intestine)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (liver)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (liver)
GENE INFORMATION
Gene name
CYP4F11
Synonyms
Description
Cytochrome P450, family 4, subfamily F, polypeptide 11 (HGNC Symbol)
Entrez gene summary
This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Enzymes ENZYME proteins Oxidoreductases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0005506 [iron ion binding] GO:0005789 [endoplasmic reticulum membrane] GO:0006805 [xenobiotic metabolic process] GO:0006954 [inflammatory response] GO:0007596 [blood coagulation] GO:0016021 [integral component of membrane] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016709 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen] GO:0020037 [heme binding] GO:0042361 [menaquinone catabolic process] GO:0042376 [phylloquinone catabolic process] GO:0042377 [vitamin K catabolic process] GO:0044281 [small molecule metabolic process] GO:0055114 [oxidation-reduction process]
Enzymes ENZYME proteins Oxidoreductases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005506 [iron ion binding] GO:0005789 [endoplasmic reticulum membrane] GO:0006805 [xenobiotic metabolic process] GO:0006954 [inflammatory response] GO:0007596 [blood coagulation] GO:0016021 [integral component of membrane] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0016709 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen] GO:0020037 [heme binding] GO:0042361 [menaquinone catabolic process] GO:0042376 [phylloquinone catabolic process] GO:0042377 [vitamin K catabolic process] GO:0044281 [small molecule metabolic process] GO:0055114 [oxidation-reduction process]