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A few cases of malignant lymphomas exhibited weak to moderate cytoplasmic positivity. Remaining malignant cells were negative.
GENE INFORMATION
Gene name
SEPT1 (HGNC Symbol)
Synonyms
DIFF6, PNUTL3
Description
Septin 1 (HGNC Symbol)
Entrez gene summary
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]