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Ovarian and thyroid cancers along with a few cases of breast, prostate, pancreatic and liver cancers exhibited weak to moderate cytoplasmic and occasional membranous positivity. Remaining cancer tissues were negative.
Most cancer tissues were negative. One case of lymphoma and melanoma as well as renal and liver cancers showed moderate cytoplasmic staining.
GENE INFORMATION
Gene name
TRMT2B (HGNC Symbol)
Synonyms
CXorf34, FLJ12687
Description
TRNA methyltransferase 2 homolog B (HGNC Symbol)
Entrez gene summary
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]
Q96GJ1 [Direct mapping] tRNA (uracil(54)-C(5))-methyltransferase homolog A0A024RCF5 [Target identity:100%; Query identity:100%] Chromosome X open reading frame 34, isoform CRA_a
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Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q96GJ1 [Direct mapping] tRNA (uracil(54)-C(5))-methyltransferase homolog A0A024RCF5 [Target identity:100%; Query identity:100%] Chromosome X open reading frame 34, isoform CRA_a
Show all
Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q96GJ1 [Direct mapping] tRNA (uracil(54)-C(5))-methyltransferase homolog A0A024RCF5 [Target identity:100%; Query identity:100%] Chromosome X open reading frame 34, isoform CRA_a
Show all
Enzymes ENZYME proteins Transferases Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)