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Cancer cells showed moderate cytoplasmic staining in most cases. A majority of lymphomas, prostate, renal and testicular cancers as well as several melanomas and endometrial caners were strongly stained.
GENE INFORMATION
Gene name
PARVA (HGNC Symbol)
Synonyms
FLJ10793, FLJ12254, MXRA2
Description
Parvin, alpha (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]