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PATHOLOGY ATLAS PANCREATIC CANCER

GENE/PROTEIN

Antibody validation

Dictionary

Pancreatic cancer

PANCREATIC CANCER - Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival, using best separation (to the left) and median separation (to the right). Patients were divided based on level of expression into one of the two groups "low" or "high". Below each Kaplan-Meier plot, corresponding expression cutoff, 5-year survival for patients with high expression, 5-year survival for patients with low expression and log-rank P value are displayed. For melanoma and glioma, 3-year survival is shown. The survival analysis is described in Assays & Annotation.

The tabs at the top of the survival analysis section can be used to switch between the different cancer subtypes.

Best separation

Median separation

Expression cutoffi

5-year survival for patients with higher expression than the expression cutoff.

89.7 FPKM 84.0 FPKM

5-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

31% 31%

5-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

23% 19%

Log-rank P valuei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

3.65e-1 4.96e-1

Interactive survival scatter plot (individual patient data)i

The Scatter Survival plot shows the clinical status for all individuals in the patient cohort, based on the same data as in the Kaplan-Meier plots. Living patients are shown in blue and deceased patients in red. The x-axis shows the expression levels (FPKM) of the investigated gene at the time of diagnosis and the y-axis shows the number of years of survival (living years) after the diagnosis.

Individual patient data is displayed in an interactive plot and can be filtered by clicking on one or several category buttons to the left. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be changed to "x linear" by clicking on the "x log" button on the left. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.




Stage:

TCGA RNA samplesi

RNA-seq data is reported as median FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average FPKM

90.9

Number of samples

176

Samples

Sample

Description

FPKM

TCGA-HV-A7OP-01A 72 years, male, asian, stage:iib 354.5
TCGA-FB-AAQ3-01A 65 years, female, white, stage:iib 290.1
TCGA-3A-A9I5-01A 58 years, male, white 248.6
TCGA-FB-A5VM-01A 74 years, male, white, stage:ib 217.1
TCGA-HZ-A4BH-01A 75 years, male, white, stage:iib 216.3
TCGA-HV-A7OL-01A 70 years, male, asian, stage:iia 196.9
TCGA-OE-A75W-01A 75 years, male, white, stage:iia 185.2
TCGA-HV-AA8X-01A 75 years, female, asian, stage:iib 183.3
TCGA-2L-AAQJ-01A 49 years, female, white, stage:iii 173.3
TCGA-IB-AAUO-01A 64 years, female, white, stage:iib 162.8
TCGA-LB-A7SX-01A 74 years, female, black or african american, stage:iib 143.6
TCGA-HV-A5A6-01A 65 years, female, asian, stage:iib 141.5
TCGA-2L-AAQA-01A 76 years, male, white, stage:iib 138.2
TCGA-LB-A8F3-01A 64 years, female, black or african american, stage:iia 135.7
TCGA-FB-AAQ1-01A 49 years, male, white, stage:iib 131.2
TCGA-US-A779-01A 54 years, female, white, stage:iib 130.6
TCGA-2J-AABP-01A 58 years, female, white, stage:iib 130.1
TCGA-IB-A7M4-01A 81 years, male, white, stage:iib 129.1
TCGA-YH-A8SY-01A 73 years, female, white 123.6
TCGA-IB-7646-01A 60 years, male, white, stage:iib 122.0
TCGA-2L-AAQM-01A 52 years, male, white, stage:iib 121.8
TCGA-3A-A9IB-01A 69 years, female, white, stage:iib 121.6
TCGA-FB-AAPY-01A 71 years, male, white, stage:iib 121.3
TCGA-IB-AAUU-01A 35 years, male, white, stage:iib 119.5
TCGA-PZ-A5RE-01A 44 years, female, white, stage:iib 118.5
TCGA-2J-AABO-01A 43 years, male, white, stage:iib 118.0
TCGA-3E-AAAY-01A 67 years, male, white, stage:iib 117.3
TCGA-3A-A9IC-01A 61 years, female, white, stage:iib 114.3
TCGA-HZ-A77O-01A 77 years, female, white, stage:iib 114.0
TCGA-IB-7889-01A 86 years, female, white, stage:iib 112.3
TCGA-HZ-8001-01A 69 years, male, white, stage:iii 110.6
TCGA-IB-7891-01A 49 years, female, white, stage:iib 110.0
TCGA-2J-AABK-01A 71 years, male, white, stage:iib 108.8
TCGA-YY-A8LH-01A 61 years, female, white, stage:iib 108.5
TCGA-Q3-AA2A-01A 64 years, female, white, stage:ib 108.5
TCGA-S4-A8RO-01A 75 years, female, white, stage:iib 107.2
TCGA-3A-A9IJ-01A 65 years, male, white, stage:ib 106.5
TCGA-2J-AABU-01A 56 years, male, white, stage:iib 105.8
TCGA-US-A77J-01A 81 years, female, white, stage:iib 105.3
TCGA-XD-AAUI-01A 50 years, female, white, stage:iib 105.2
TCGA-IB-AAUN-01A 74 years, female, white, stage:ib 104.5
TCGA-FB-AAQ6-01A 85 years, male, white, stage:ia 104.2
TCGA-2L-AAQL-01A 82 years, male, white, stage:iib 102.9
TCGA-3A-A9IH-01A 66 years, female, white, stage:ia 100.9
TCGA-2J-AAB8-01A 71 years, male, white, stage:iib 99.6
TCGA-Z5-AAPL-01A 74 years, female, white, stage:iia 99.6
TCGA-3A-A9IL-01A 39 years, female, white, stage:i 99.1
TCGA-2J-AABI-01A 55 years, female, white, stage:iia 99.0
TCGA-FB-AAQ0-01A 68 years, male, white, stage:iia 98.8
TCGA-RL-AAAS-01A 60 years, female, white, stage:ib 98.7
TCGA-FB-A7DR-01A 48 years, male, asian, stage:iia 97.3
TCGA-FB-A4P5-01A 69 years, female, white, stage:iib 96.6
TCGA-H8-A6C1-01A 53 years, male, white, stage:iia 96.3
TCGA-IB-AAUQ-01A 50 years, male, white, stage:iib 95.9
TCGA-Q3-A5QY-01A 58 years, male, white, stage:iib 94.2
TCGA-IB-7885-01A 78 years, female, white, stage:iib 93.9
TCGA-F2-A44G-01A 79 years, female, white, stage:iib 93.9
TCGA-F2-A7TX-01A 77 years, male, white, stage:iib 93.5
TCGA-2J-AAB1-01A 65 years, male, white, stage:iib 93.2
TCGA-IB-AAUS-01A 84 years, female, white, stage:iib 92.9
TCGA-3A-A9J0-01A 75 years, male, white, stage:iib 91.2
TCGA-IB-A5SP-01A 77 years, male, white, stage:iia 90.6
TCGA-3A-A9IU-01A 65 years, male, white, stage:iib 90.5
TCGA-RB-A7B8-01A 81 years, female, white, stage:iib 90.3
TCGA-IB-A5SQ-01A 56 years, female, white, stage:ib 90.3
TCGA-FB-AAQ2-01A 81 years, female, white, stage:iib 90.1
TCGA-HZ-8637-01A 76 years, female, white, stage:iib 89.7
TCGA-XD-AAUL-01A 56 years, male, white, stage:iia 89.7
TCGA-YB-A89D-01A 59 years, male, white, stage:iib 89.4
TCGA-FB-A78T-01A 71 years, female, white, stage:iib 89.3
TCGA-US-A776-01A 61 years, male, white, stage:iia 89.0
TCGA-HZ-A77Q-01A 55 years, female, white, stage:iib 88.6
TCGA-RB-AA9M-01A 43 years, male, white, stage:iib 88.4
TCGA-IB-7887-01A 62 years, female, white, stage:iib 88.2
TCGA-3A-A9IR-01A 64 years, female, white, stage:ib 87.9
TCGA-FB-AAPS-01A 62 years, female, white, stage:iib 87.6
TCGA-HZ-7919-01A 52 years, female, white, stage:iib 87.3
TCGA-IB-A7LX-01A 57 years, male, white, stage:iib 87.2
TCGA-3E-AAAZ-01A 71 years, male, white, stage:iia 86.8
TCGA-M8-A5N4-01A 48 years, female, stage:iia 86.6
TCGA-2L-AAQE-01A 56 years, male, white, stage:iib 85.1
TCGA-IB-A5ST-01A 64 years, female, white, stage:iib 85.0
TCGA-FB-A545-01A 72 years, female, white, stage:iib 85.0
TCGA-HZ-A49I-01A 77 years, male, white, stage:iib 84.9
TCGA-HV-A5A5-01A 61 years, female, asian, stage:iib 84.7
TCGA-IB-A5SS-01A 64 years, female, white, stage:iib 84.2
TCGA-FB-AAPQ-01A 65 years, male, white, stage:iib 84.0
TCGA-IB-7649-01A 73 years, female, stage:iib 84.0
TCGA-HZ-A9TJ-01A 70 years, male, white, stage:iv 83.9
TCGA-2J-AAB4-01A 48 years, male, white, stage:iib 83.9
TCGA-HZ-A4BK-01A 72 years, male, white, stage:iib 83.3
TCGA-2J-AAB6-01A 75 years, male, white, stage:iia 82.8
TCGA-FB-AAPU-01A 41 years, female, asian, stage:iia 82.5
TCGA-2J-AABF-01A 73 years, male, white, stage:iib 81.6
TCGA-HZ-A8P1-01A 81 years, male, white, stage:ib 81.0
TCGA-HZ-A49H-01A 68 years, female, white, stage:iib 80.4
TCGA-US-A77E-01A 73 years, male, white, stage:iib 80.0
TCGA-2J-AABH-01A 61 years, male, white, stage:iia 79.6
TCGA-US-A774-01A 76 years, female, white, stage:iib 79.5
TCGA-FB-AAPZ-01A 54 years, male, white, stage:iib 79.2
TCGA-XN-A8T5-01A 53 years, female, white, stage:ib 78.7
TCGA-3A-A9I7-01A 45 years, male, black or african american, stage:iib 78.0
TCGA-2L-AAQI-01A 66 years, male, white, stage:iib 76.8
TCGA-3A-A9IN-01A 62 years, female, white, stage:ib 76.8
TCGA-IB-7888-01A 66 years, female, black or african american, stage:iia 75.8
TCGA-IB-AAUR-01A 67 years, male, white, stage:iib 75.7
TCGA-HZ-7289-01A 77 years, male, white, stage:iib 75.3
TCGA-XN-A8T3-01A 67 years, male, white, stage:ib 75.2
TCGA-HZ-7920-01A 71 years, male, white, stage:ib 74.6
TCGA-IB-7651-01A 64 years, female, white, stage:iib 74.5
TCGA-IB-7893-01A 64 years, male, white, stage:iia 74.3
TCGA-HV-A5A3-01A 50 years, male, asian, stage:iia 74.3
TCGA-HZ-A49G-01A 58 years, female, white, stage:iib 73.7
TCGA-HZ-7918-01A 72 years, male, white, stage:iib 73.7
TCGA-IB-AAUP-01A 68 years, male, white, stage:iib 72.8
TCGA-2J-AABE-01A 73 years, male, white, stage:iia 72.7
TCGA-FB-AAPP-01A 71 years, male, white, stage:iib 72.6
TCGA-3A-A9IO-01A 56 years, male, white 72.3
TCGA-HZ-8638-01A 84 years, female, white, stage:ia 72.2
TCGA-HZ-7922-01A 61 years, female, white, stage:iib 72.1
TCGA-IB-AAUT-01A 65 years, male, white, stage:iib 72.0
TCGA-3A-A9IZ-01A 47 years, male, white, stage:iib 71.9
TCGA-2J-AABA-01A 55 years, male, white, stage:iib 71.6
TCGA-2J-AAB9-01A 71 years, female, white, stage:iib 71.3
TCGA-H6-A45N-01A 88 years, female, white, stage:iib 70.7
TCGA-IB-A5SO-01A 71 years, male, white, stage:iib 70.4
TCGA-3A-A9IV-01A 59 years, female, white, stage:ib 70.3
TCGA-US-A77G-01A 64 years, male, white, stage:iib 70.1
TCGA-IB-7645-01A 44 years, female, stage:iib 69.8
TCGA-H6-8124-01A 56 years, female, white, stage:iib 69.4
TCGA-HZ-A77P-01A 77 years, male, white, stage:iib 69.2
TCGA-S4-A8RP-01A 77 years, female, white, stage:iib 68.7
TCGA-IB-8127-01A 59 years, male, white, stage:iib 68.6
TCGA-HV-A5A4-01A 72 years, female, asian, stage:iia 68.5
TCGA-IB-7886-01A 80 years, male, white, stage:iib 68.1
TCGA-XD-AAUH-01A 57 years, female, white, stage:iib 68.0
TCGA-F2-A44H-01A 65 years, male, white, stage:iia 67.9
TCGA-IB-A6UG-01A 65 years, male, white, stage:iib 66.1
TCGA-HZ-8002-01A 61 years, male, white, stage:iib 66.0
TCGA-IB-7644-01A 65 years, female, white, stage:iv 65.7
TCGA-IB-A6UF-01A 63 years, male, white, stage:iib 65.7
TCGA-HZ-7925-01A 66 years, male, white, stage:iib 65.2
TCGA-HV-AA8V-01A 50 years, male, asian, stage:iib 64.9
TCGA-2J-AABR-01A 60 years, female, white, stage:iia 64.4
TCGA-HZ-8315-01A 54 years, female, white, stage:iia 63.8
TCGA-HZ-7926-01A 57 years, male, black or african american, stage:iib 63.3
TCGA-F2-7276-01A 64 years, male, white, stage:iib 62.7
TCGA-3A-A9I9-01A 67 years, male, white, stage:iia 62.6
TCGA-HZ-8519-01A 73 years, male, white, stage:ia 62.3
TCGA-F2-6879-01A 57 years, male, white, stage:iib 61.8
TCGA-2J-AABT-01A 72 years, female, white, stage:iib 61.0
TCGA-3A-A9IS-01A 67 years, male, white, stage:ib 59.3
TCGA-IB-AAUV-01A 49 years, male, white, stage:iib 59.0
TCGA-HZ-8636-01A 58 years, female, white, stage:iv 58.8
TCGA-IB-AAUW-01A 63 years, female, white, stage:iib 57.7
TCGA-IB-7890-01A 73 years, male, stage:ib 57.2
TCGA-HZ-7924-01A 60 years, female, white, stage:iia 57.2
TCGA-2J-AABV-01A 74 years, male, white, stage:iib 56.3
TCGA-3A-A9IX-01A 40 years, male, white, stage:ia 56.2
TCGA-LB-A9Q5-01A 63 years, female, white, stage:iib 56.1
TCGA-FB-A4P6-01A 54 years, male, white, stage:iib 55.4
TCGA-XD-AAUG-01A 66 years, female, white, stage:iv 53.4
TCGA-IB-7654-01A 80 years, male, white, stage:iib 52.3
TCGA-HZ-8317-01A 69 years, female, white, stage:iib 51.9
TCGA-F2-7273-01A 54 years, male, black or african american, stage:iib 51.5
TCGA-HZ-7923-01A 65 years, male, white, stage:iia 51.0
TCGA-IB-7897-01A 54 years, female, white, stage:iib 50.3
TCGA-S4-A8RM-01A 67 years, male, white, stage:iib 50.2
TCGA-HZ-8005-01A 81 years, male, white, stage:iib 49.1
TCGA-F2-A8YN-01A 76 years, male, white, stage:iia 48.5
TCGA-L1-A7W4-01A 48 years, female, white, stage:iib 46.1
TCGA-IB-7652-01A 49 years, female, asian, stage:iib 42.0
TCGA-IB-AAUM-01A 76 years, male, white, stage:iib 37.9
TCGA-HZ-8003-01A 65 years, female, white, stage:iib 34.3
TCGA-IB-8126-01A 80 years, female, white, stage:iii 30.0
TCGA-F2-6880-01A 70 years, male, white, stage:iib 20.6
Show all

PANCREATIC CANCER - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

Antibody HPA042775

Antibody HPA048147

 Antibody staining
  High
  Medium
  Low
  Not detected
   
 Intensity
  Strong
  Moderate
  Weak
  Negative
   
 Quantity
  >75%
  75%-25%
  <25%
  Rare
  Negative
   
 Location
  Cytoplasmic/membranous,nuclear
  Cytoplasmic/membranous
  Nuclear
  None
   

Click images for details











































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