The human protein atlas blog


NFIL3 a protein that follows the winter season

2017-11-24
Cell Atlas cells Immunofluorescence microscopy

Staining of NFIL3 (green) in nuclear bodies with DNA (blue) and microtubules (red) in A-431 cells.

Staining of NFIL3 (green) in nuclear bodies with DNA (blue) and microtubules (red) in A-431 cells. Many human genes follow a so called circadian clock and research has shown that some of those genes themselves follow the seasons (Dopico et al. 2015). When winter is coming, you sense it and your genes know it too. Expression of one of those genes, NFIL3, peaks during December until February and has its lowest expression during the summer months.

NFIL3 is a transcriptional regulator involved in regulation of immune processes. Like many other transcription regulators it localizes to nuclear bodies as seen on the Cell Atlas images and binds to specific DNA motifs...Read more


The HPA at the Image-based Cell Atlas Meeting

2017-10-06
Cell Atlas Chan-Zuckerberg Initiative Image analysis Immunofluorescence microscopy Proteomics

Participants at the Image-based Cell Atlas Meeting 2017

The importance of mapping the human cell has become recognized as one of the key challenges in modern biology. Image-based assays offer a data-rich medium of studying cells and their proteins in situ. As such, several large-scale initiatives for studying cellular biology using image-based assays have been founded in recent years...Read more


Human Protein Atlas presentations at the 16th HUPO World Congress

2017-09-14
Affinity proteomics Cell Atlas Conference Human Protein Atlas Immunofluorescence microscopy Immunohistochemistry Sub-cellular structures Tissue Atlas

Next week on the 17th to 21th of September, the human proteome organization (HUPO), is hosting the 16th HUPO World Congress in Dublin, Ireland. Several Human Protein Atlas-associated researchers will attend the meeting and represent the project in various sessions, including plenary and invited lectures, oral presentations and poster sessions.

HUPO is an international scientific organization representing and promoting proteomics through international cooperation and collaborations by fostering the development of new technologies, techniques and training...Read more


Symposium celebrating 100-years anniversary Knut and Alice Wallenberg foundation

2017-09-08
Cell Atlas Conference Human Protein Atlas Immunofluorescence microscopy Project Discovery Subcell Atlas subcellular structures

The Knut and Alice Wallenberg Foundation (KAW) cellebrates 100-years anniversary of funding research within natural sciences, technology and medicine. Since 1917, when KAW was established, grants have been awarded to enpower both scientific research and education beneficial for the society. Today the foundation is one of the largest private funders of scientific research in Europe.

The KAW funded Molecular Life Science - anniversary symposium is organised by the Royal Academy of Sciences together with KTH - The Royal Institute of Technology, Karolinska Institute and Stockholm University...Read more


Keynote lecture at CYTO2017 in Boston

2017-06-12
Cell Atlas cell lines CYTO2017 Human Protein Atlas Immunofluorescence microscopy Single cell analysis

Emma Lundberg Director of the Human Cell Atlas, will present a keynote lecture on June 14th, entitled ”The Cell Atlas: A subcellular map of the human proteome” on the 32ndCongress of the International Society for Advancement of Cytometry in Boston, USA.

On this occassion, the CYTO Congress together with the Human Protein Atlas have organized a challenge for analysis of the images from the Cell Atlas, culminating in presentation of results in the final conference session, where participants will present their analytical methods and findings...Read more


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