Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific ADCK1 FLJ39600 ENSG00000063761 AarF domain containing kinase 1 14 77800083-77935012 Enzymes, Predicted secreted proteins Evidence at protein level HPA051012, HPA055014 Uncertain Approved Nucleoplasm Renal cancer:5.82e-6 (favourable), Lung cancer:4.11e-5 (favourable), Liver cancer:1.70e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 9.0 ADCK2 MGC20727 ENSG00000133597 AarF domain containing kinase 2 7 140673153-140696261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036036 Approved Uncertain Centrosome
Cytosol Renal cancer:9.75e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 26.7 ADCK3 CABC1, COQ8, SCAR9 ENSG00000163050 AarF domain containing kinase 3 1 226897536-226987545 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA061662 Supported Mitochondria Expressed in all Tissue enriched 6 skeletal muscle: 401.9 adrenal gland: 68.5 ADCK4 COQ8, FLJ12229 ENSG00000123815 AarF domain containing kinase 4 19 40691529-40718207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027229, HPA027277, HPA027279, HPA028303 Supported Validated Mitochondria Expressed in all Expressed in all fallopian tube: 40.7 ADCK5 FLJ35454 ENSG00000173137 AarF domain containing kinase 5 8 144373101-144393242 Enzymes, Predicted membrane proteins Evidence at protein level HPA025692, HPA028679 Approved Approved Plasma membrane
Cytosol Expressed in all Mixed duodenum: 9.9 ALPK1 FLJ22670, KIAA1527, Lak ENSG00000073331 Alpha-kinase 1 4 112285509-112442620 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA027435, HPA027443 Approved Approved Centrosome Renal cancer:5.82e-7 (unfavourable), Urothelial cancer:1.17e-4 (favourable) Expressed in all Mixed parathyroid gland: 9.2 ALPK2 HAK ENSG00000198796 Alpha-kinase 2 18 58481247-58628957 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA027377, HPA027976, HPA028084, HPA029801 Uncertain Approved Cytosol Renal cancer:8.20e-5 (unfavourable) Tissue enriched Tissue enhanced heart muscle: 28.3;skeletal muscle: 14.1 lymph node: 6.9 ALPK3 KIAA1330, MAK, Midori ENSG00000136383 Alpha-kinase 3 15 84816680-84873482 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026558 Uncertain Approved Nucleus Renal cancer:3.95e-7 (favourable) Mixed Tissue enhanced heart muscle: 32.4;parathyroid gland: 35.6;skeletal muscle: 47.6 adipose tissue: 12.3 ATM ATA, ATC, ATD, ATDC, TEL1, TELO1 ENSG00000149311 ATM serine/threonine kinase 11 108222484-108369102 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000102, HPA067142 Supported Supported Nucleoplasm Expressed in all Expressed in all lymph node: 41.6 ATR FRP1, MEC1, SCKL, SCKL1 ENSG00000175054 ATR serine/threonine kinase 3 142449235-142578826 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054320 Supported Nucleoplasm
Golgi apparatus Pancreatic cancer:1.23e-5 (unfavourable), Liver cancer:8.39e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 15.2 BCKDK ENSG00000103507 Branched chain ketoacid dehydrogenase kinase 16 31106107-31112791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017995, HPA056067 Supported Supported Mitochondria Expressed in all Expressed in all parathyroid gland: 33.6 EEF2K eEF-2K ENSG00000103319 Eukaryotic elongation factor 2 kinase 16 22206282-22288732 Enzymes, Predicted intracellular proteins Evidence at protein level CAB007818, HPA056061 Approved Approved Nucleoplasm Renal cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all skin: 57.5 FASTK FAST ENSG00000164896 Fas-activated serine/threonine kinase 7 151076593-151080866 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031621, CAB032539 Approved Approved Nuclear speckles
Mitochondria Pancreatic cancer:3.99e-4 (favourable), Colorectal cancer:4.73e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 41.7 MTOR FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 ENSG00000198793 Mechanistic target of rapamycin (serine/threonine kinase) 1 11106535-11262507 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB069425, HPA071227 Approved Approved Vesicles
Cytosol Renal cancer:1.49e-5 (favourable) Expressed in all Expressed in all testis: 62.0 PDK1 ENSG00000152256 Pyruvate dehydrogenase kinase, isozyme 1 2 172555373-172608669 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017554, HPA027376, HPA059083 Approved Approved Nucleoli
Mitochondria Renal cancer:1.10e-8 (unfavourable), Cervical cancer:7.30e-5 (unfavourable) Expressed in all Expressed in all testis: 22.3 PDK2 PDHK2 ENSG00000005882 Pyruvate dehydrogenase kinase, isozyme 2 17 50094737-50112152 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008287 Supported Supported Nucleoplasm
Mitochondria Renal cancer:9.59e-5 (favourable), Cervical cancer:5.87e-4 (favourable) Expressed in all Expressed in all epididymis: 149.0 PDK3 ENSG00000067992 Pyruvate dehydrogenase kinase, isozyme 3 X 24465221-24539837 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046583, HPA072492 Approved Supported Nucleoli
Mitochondria Liver cancer:2.76e-4 (unfavourable) Expressed in all Mixed testis: 24.8 PDK4 ENSG00000004799 Pyruvate dehydrogenase kinase, isozyme 4 7 95583499-95596491 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056731 Approved Stomach cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 756.5 PIK3CA PI3K ENSG00000121879 Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3 179148114-179240093 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA009985, CAB017804 Approved Approved Cytosol Expressed in all Mixed parathyroid gland: 23.9 PIK3CG ENSG00000105851 Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7 106865278-106907145 Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA069976 Supported Plasma membrane Mixed Tissue enhanced bone marrow: 28.2 lymph node: 22.2 PRKDC DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7 ENSG00000253729 Protein kinase, DNA-activated, catalytic polypeptide 8 47773108-47960183 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005167, HPA035174 Supported Validated Nucleoplasm Endometrial cancer:1.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.0 RIOK1 AD034, bA288G3.1, FLJ30006, RRP10 ENSG00000124784 RIO kinase 1 6 7389496-7418037 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017866, HPA051446 Supported Approved Nucleoli
Nuclear speckles
Cytosol Liver cancer:3.41e-5 (unfavourable), Renal cancer:5.85e-5 (unfavourable), Melanoma:4.43e-4 (unfavourable) Expressed in all Expressed in all testis: 29.5 RIOK2 FLJ11159 ENSG00000058729 RIO kinase 2 5 97160867-97183260 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005681 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all testis: 22.0 RIOK3 SUDD ENSG00000101782 RIO kinase 3 18 23452823-23486603 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001620, HPA024184 Approved Approved Golgi apparatus
Plasma membrane
Microtubule organizing center
Cytosol Pancreatic cancer:4.10e-4 (unfavourable), Prostate cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 75.0 SMG1 ATX, KIAA0421, LIP ENSG00000157106 SMG1 phosphatidylinositol 3-kinase-related kinase 16 18804853-18926454 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006870, HPA031623, HPA073972 Approved Supported Nucleoplasm Expressed in all Expressed in all skin: 50.3 TRPM6 CHAK2, FLJ22628, HOMG, HSH ENSG00000119121 Transient receptor potential cation channel, subfamily M, member 6 9 74722495-74888094 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enhanced colon: 13.3;rectum: 18.5 small intestine: 8.9 TRPM7 CHAK1, LTRPC7, TRP-PLIK ENSG00000092439 Transient receptor potential cation channel, subfamily M, member 7 15 50552473-50686815 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA035523, HPA052173 Uncertain Approved Nucleoplasm Expressed in all Tissue enriched 7 parathyroid gland: 212.8 thyroid gland: 29.0