Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific AMER1 FAM123B, FLJ39827, RP11-403E24.2, WTX ENSG00000184675 APC membrane recruitment protein 1 X 64185117-64205744 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065214, HPA065265 Approved Supported Nuclear bodies
Vesicles
Plasma membrane Expressed in all Mixed ovary: 7.7 APC DP2, DP2.5, DP3, PPP1R46 ENSG00000134982 Adenomatous polyposis coli 5 112707498-112846239 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013349, CAB025994 Approved Expressed in all Tissue enhanced cerebral cortex: 60.3 parathyroid gland: 19.5 ARID1A B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1 ENSG00000117713 AT rich interactive domain 1A (SWI-like) 1 26696033-26782104 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005456, CAB016334 Supported Validated Nucleoplasm Liver cancer:4.18e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.4 ATM ATA, ATC, ATD, ATDC, TEL1, TELO1 ENSG00000149311 ATM serine/threonine kinase 11 108222484-108369102 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000102, HPA067142 Supported Supported Nucleoplasm Expressed in all Expressed in all lymph node: 41.6 AXIN1 PPP1R49 ENSG00000103126 Axin 1 16 287440-352673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012987 Approved Supported Nucleoli
Vesicles Liver cancer:3.38e-5 (unfavourable) Expressed in all Expressed in all spleen: 15.8 BIRC3 API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49 ENSG00000023445 Baculoviral IAP repeat containing 3 11 102317450-102339403 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002317 Supported Approved Supported Nucleoplasm
Cytosol Renal cancer:6.66e-6 (unfavourable), Pancreatic cancer:3.03e-4 (unfavourable), Breast cancer:3.60e-4 (favourable), Colorectal cancer:9.35e-4 (favourable) Expressed in all Tissue enhanced lymph node: 139.7 appendix: 121.3 BRCA1 BRCC1, FANCS, PPP1R53, RNF53 ENSG00000012048 Breast cancer 1, early onset 17 43044295-43170245 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001946, HPA034966 Approved Expressed in all Mixed testis: 23.9 BRCA2 BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11 ENSG00000139618 Breast cancer 2, early onset 13 32315474-32400266 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026815 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 5.1 bone marrow: 4.1 CDKN2A ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf ENSG00000147889 Cyclin-dependent kinase inhibitor 2A 9 21967753-21995301 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000093, CAB000445, CAB018232, HPA047838 Uncertain Validated Nucleoli Endometrial cancer:1.82e-7 (unfavourable), Renal cancer:5.76e-7 (unfavourable), Liver cancer:2.17e-4 (unfavourable), Head and neck cancer:5.19e-4 (favourable) Expressed in all Mixed parathyroid gland: 7.5 CDKN2C INK4C, p18 ENSG00000123080 Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1 50960745-50974633 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005303, CAB018398, HPA019057, HPA019764 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.70e-10 (unfavourable), Liver cancer:1.58e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 80.3 FANCA FA-H, FAA, FACA, FAH, FANCH ENSG00000187741 Fanconi anemia, complementation group A 16 89737549-89816657 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063236 Supported Nucleus Mixed Mixed testis: 19.5 FANCC FA3, FAC, FACC ENSG00000158169 Fanconi anemia, complementation group C 9 95099054-95317709 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017793, HPA030771 Approved Supported Nucleoplasm Renal cancer:6.03e-6 (favourable) Expressed in all Mixed testis: 18.1 FANCD2 FA-D2, FACD, FAD, FANCD ENSG00000144554 Fanconi anemia, complementation group D2 3 10026414-10101930 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016117, HPA063742 Approved Supported Nucleus
Nuclear bodies
Cytosol Ovarian cancer:5.00e-5 (unfavourable) Expressed in all Mixed testis: 21.7 FBXO11 FBX11, UBR6 ENSG00000138081 F-box protein 11 2 47789316-47905793 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002690 Uncertain Supported Nucleus Expressed in all Expressed in all testis: 74.9 FBXW7 AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10 ENSG00000109670 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 4 152321259-152536101 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB013793, CAB029987 Supported Supported Nucleoplasm
Vesicles Renal cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all skin: 87.7 GPC3 DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1 ENSG00000147257 Glypican 3 X 133535745-133985895 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006316 Approved Plasma membrane Stomach cancer:4.83e-4 (unfavourable) Expressed in all Tissue enriched 6 placenta: 838.1 lung: 130.8 IKZF1 hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1 ENSG00000185811 IKAROS family zinc finger 1 (Ikaros) 7 50304124-50405101 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB009247, HPA035221, HPA035222 Supported Approved Nucleoplasm
Nucleoli
Vesicles Cervical cancer:2.02e-4 (favourable), Breast cancer:4.28e-4 (favourable), Head and neck cancer:8.63e-4 (favourable) Expressed in all Tissue enhanced lymph node: 84.0;tonsil: 58.0 appendix: 55.9 KDM6A UTX ENSG00000147050 Lysine (K)-specific demethylase 6A X 44873177-45112602 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000568, HPA001165, HPA002111 Supported Approved Nucleoli Expressed in all Expressed in all bone marrow: 41.1 MAP2K4 JNKK1, MEK4, MKK4, PRKMK4, SERK1 ENSG00000065559 Mitogen-activated protein kinase kinase 4 17 12020824-12143830 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007751, HPA060074 Supported Approved Nucleoplasm
Cell Junctions Expressed in all Expressed in all cerebral cortex: 64.2 MEN1 ENSG00000133895 Multiple endocrine neoplasia I 11 64803510-64811294 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030342 Uncertain Supported Nucleoplasm
Cytosol Stomach cancer:6.31e-5 (favourable), Liver cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 22.2 MLH1 COCA2, FCC2, HNPCC, HNPCC2 ENSG00000076242 MutL homolog 1 3 36993332-37050918 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013294, HPA052707, HPA060714, CAB070868 Supported Validated Nucleoplasm Liver cancer:8.24e-5 (unfavourable) Expressed in all Expressed in all testis: 59.7 MSH2 COCA1, HNPCC, HNPCC1 ENSG00000095002 MutS homolog 2 2 47402969-47562311 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009572, CAB070867 Supported Approved Nucleoplasm
Vesicles Liver cancer:1.72e-9 (unfavourable), Endometrial cancer:4.44e-4 (unfavourable), Pancreatic cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 32.6 NF1 ENSG00000196712 Neurofibromin 1 17 31094927-31382116 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA045502 Uncertain Approved Mitochondria Expressed in all Expressed in all parathyroid gland: 31.9 NF2 merlin ENSG00000186575 Neurofibromin 2 (merlin) 22 29603556-29698598 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003097, CAB005385 Supported Validated Nucleus
Plasma membrane
Cytosol Renal cancer:2.89e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 57.6 PAX5 BSAP ENSG00000196092 Paired box 5 9 36833275-37034185 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026269, CAB026869, HPA056394, HPA068498 Supported Approved Nucleoplasm
Vesicles
Cytosol Mixed Tissue enhanced lymph node: 49.1;spleen: 26.7;tonsil: 35.2 appendix: 20.2 PBRM1 BAF180, PB1 ENSG00000163939 Polybromo 1 3 52545352-52685917 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015629, HPA059373 Uncertain Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 44.5 PRDM1 BLIMP1, PRDI-BF1 ENSG00000057657 PR domain containing 1, with ZNF domain 6 106086320-106109939 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030033 Approved Approved Nucleus
Nucleoli Renal cancer:9.81e-5 (unfavourable) Expressed in all Tissue enhanced esophagus: 61.3 endometrium: 30.1 PTEN BZS, MHAM, MMAC1, PTEN1, TEP1 ENSG00000171862 Phosphatase and tensin homolog 10 87863113-87971930 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004076, HPA031335 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:7.35e-4 (unfavourable) Expressed in all Mixed testis: 59.0 RB1 OSRC, PPP1R130, RB ENSG00000139687 Retinoblastoma 1 13 48303751-48481986 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000095, CAB016687, HPA050082 Supported Validated Nucleoplasm Ovarian cancer:6.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.0 SMAD4 DPC4, MADH4 ENSG00000141646 SMAD family member 4 18 51028394-51085045 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019154 Approved Supported Nucleoplasm
Centrosome
Cytosol Renal cancer:1.92e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 38.7 SMARCB1 BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1 ENSG00000099956 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 22 23786963-23834516 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009196, HPA018248, HPA019127 Supported Supported Nucleoplasm
Nucleoli fibrillar center Renal cancer:1.14e-6 (favourable), Liver cancer:6.52e-4 (unfavourable) Expressed in all Expressed in all testis: 51.2 STK11 LKB1, PJS ENSG00000118046 Serine/threonine kinase 11 19 1177558-1228435 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB016231, HPA017254, CAB022105, HPA067481 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:3.69e-5 (favourable), Head and neck cancer:1.96e-4 (favourable) Expressed in all Expressed in all testis: 70.3 SUFU PRO1280, SUFUH, SUFUXL ENSG00000107882 Suppressor of fused homolog (Drosophila) 10 102503987-102633535 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008700 Supported Supported Nucleus Expressed in all Mixed parathyroid gland: 15.8 TNFAIP3 A20, OTUD7C ENSG00000118503 Tumor necrosis factor, alpha-induced protein 3 6 137867188-137883312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002116 Approved Approved Centrosome
Cytosol Renal cancer:6.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 345.8 TSC1 hamartin, KIAA0243, LAM, TSC ENSG00000165699 Tuberous sclerosis 1 9 132891348-132944633 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011568, CAB012481, HPA074132 Supported Validated Cytosol Liver cancer:6.03e-6 (unfavourable), Renal cancer:7.91e-4 (favourable), Pancreatic cancer:8.01e-4 (favourable) Expressed in all Expressed in all testis: 34.3 TSC2 LAM, PPP1R160, TSC4, tuberin ENSG00000103197 Tuberous sclerosis 2 16 2047465-2088720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002225, HPA030409, HPA049679 Approved Validated Cytosol Pancreatic cancer:5.06e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 35.7 VHL VHL1 ENSG00000134086 Von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 3 10141008-10152220 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB005430, HPA031631, HPA031632 Uncertain Validated Nucleoplasm
Cytosol Liver cancer:1.32e-5 (unfavourable), Breast cancer:9.02e-5 (unfavourable), Stomach cancer:7.84e-4 (favourable) Expressed in all Expressed in all lymph node: 35.2 WT1 AWT1, GUD, WAGR, WIT-2 ENSG00000184937 Wilms tumor 1 11 32387775-32435630 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000327, HPA035717, HPA053848 Supported Supported Nucleoplasm Tissue enriched Tissue enhanced endometrium: 112.0;fallopian tube: 123.1;smooth muscle: 78.9 testis: 53.8