Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific AMER1 FAM123B, FLJ39827, RP11-403E24.2, WTX ENSG00000184675 APC membrane recruitment protein 1 X 64185117-64205744 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065214, HPA065265 Approved Supported Nuclear bodies
Vesicles
Plasma membrane Expressed in all Mixed ovary: 7.7 APC DP2, DP2.5, DP3, PPP1R46 ENSG00000134982 Adenomatous polyposis coli 5 112707498-112846239 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013349, CAB025994 Approved Expressed in all Tissue enhanced cerebral cortex: 60.3 parathyroid gland: 19.5 ARID1A B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1 ENSG00000117713 AT rich interactive domain 1A (SWI-like) 1 26696033-26782104 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005456, CAB016334 Supported Validated Nucleoplasm Liver cancer:4.18e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.4 ARID1B 6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R ENSG00000049618 AT rich interactive domain 1B (SWI1-like) 6 156777374-157210779 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016511, HPA075291 Approved Supported Nucleoplasm Breast cancer:1.04e-4 (unfavourable), Ovarian cancer:4.16e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.6 ARID2 BAF200, DKFZp686G052, FLJ30619, KIAA1557 ENSG00000189079 AT rich interactive domain 2 (ARID, RFX-like) 12 45729665-45908040 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063044 Supported Nucleoplasm
Plasma membrane Head and neck cancer:5.75e-4 (favourable) Expressed in all Expressed in all testis: 47.3 ASXL1 KIAA0978 ENSG00000171456 Additional sex combs like transcriptional regulator 1 20 32358344-32439319 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064156 Approved Nucleus
Nucleoli Endometrial cancer:2.86e-4 (unfavourable), Head and neck cancer:9.16e-4 (favourable) Expressed in all Expressed in all testis: 68.2 ATM ATA, ATC, ATD, ATDC, TEL1, TELO1 ENSG00000149311 ATM serine/threonine kinase 11 108222484-108369102 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000102, HPA067142 Supported Supported Nucleoplasm Expressed in all Expressed in all lymph node: 41.6 ATRX JMS, MRX52, RAD54, XH2, XNP ENSG00000085224 Alpha thalassemia/mental retardation syndrome X-linked X 77504878-77786269 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001906, CAB009372, HPA064684, CAB068176 Supported Supported Nuclear bodies Expressed in all Expressed in all parathyroid gland: 53.5 AXIN1 PPP1R49 ENSG00000103126 Axin 1 16 287440-352673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012987 Approved Supported Nucleoli
Vesicles Liver cancer:3.38e-5 (unfavourable) Expressed in all Expressed in all spleen: 15.8 AXIN2 DKFZp781B0869, MGC126582 ENSG00000168646 Axin 2 17 65528563-65561647 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB012283, CAB017783 Approved Uncertain Nucleus
Plasma membrane
Cytosol Pancreatic cancer:6.58e-4 (favourable) Expressed in all Mixed endometrium: 31.0 BAP1 hucep-6, KIAA0272, UCHL2 ENSG00000163930 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 3 52401013-52410350 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004322, HPA028814, HPA028815, HPA055560 Approved Validated Nucleoplasm
Cytosol Renal cancer:3.29e-7 (favourable) Expressed in all Expressed in all testis: 118.1 BCOR FLJ20285, KIAA1575 ENSG00000183337 BCL6 corepressor X 40049815-40177329 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056308, HPA066234 Validated Nucleus Liver cancer:1.30e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.3 BIRC3 API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49 ENSG00000023445 Baculoviral IAP repeat containing 3 11 102317450-102339403 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002317 Supported Approved Supported Nucleoplasm
Cytosol Renal cancer:6.66e-6 (unfavourable), Pancreatic cancer:3.03e-4 (unfavourable), Breast cancer:3.60e-4 (favourable), Colorectal cancer:9.35e-4 (favourable) Expressed in all Tissue enhanced lymph node: 139.7 appendix: 121.3 BLM BS, RECQ2, RECQL3 ENSG00000197299 Bloom syndrome, RecQ helicase-like 15 90717327-90816165 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005689 Approved Supported Nucleus
Cytosol Mixed Mixed lymph node: 3.8 BMPR1A ACVRLK3, ALK3, CD292 ENSG00000107779 Bone morphogenetic protein receptor, type IA 10 86756650-86932838 Cancer-related genes, CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB019398 Approved Approved Cytosol Liver cancer:8.93e-4 (unfavourable), Glioma:9.38e-4 (favourable) Expressed in all Mixed thyroid gland: 33.8 BRCA1 BRCC1, FANCS, PPP1R53, RNF53 ENSG00000012048 Breast cancer 1, early onset 17 43044295-43170245 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001946, HPA034966 Approved Expressed in all Mixed testis: 23.9 BRCA2 BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11 ENSG00000139618 Breast cancer 2, early onset 13 32315474-32400266 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026815 Uncertain Approved Nucleoplasm
Cytosol Mixed Tissue enhanced testis: 5.1 bone marrow: 4.1 BRIP1 BACH1, FANCJ, OF ENSG00000136492 BRCA1 interacting protein C-terminal helicase 1 17 61681266-61863521 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005474 Approved Supported Nucleus
Nuclear membrane Colorectal cancer:3.45e-5 (favourable), Head and neck cancer:3.62e-4 (favourable) Mixed Tissue enhanced testis: 14.4 bone marrow: 5.0 BUB1B Bub1A, BUBR1, MAD3L, SSK1 ENSG00000156970 BUB1 mitotic checkpoint serine/threonine kinase B 15 40161023-40221136 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008419 Supported Cytosol Liver cancer:7.43e-6 (unfavourable), Pancreatic cancer:1.79e-4 (unfavourable), Lung cancer:3.56e-4 (unfavourable) Expressed in all Tissue enhanced testis: 40.2 lymph node: 15.1 CASP8 Casp-8, FLICE, MACH, MCH5 ENSG00000064012 Caspase 8, apoptosis-related cysteine peptidase 2 201233443-201287711 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001302, CAB002047, HPA005688, HPA006191 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.27e-6 (unfavourable), Ovarian cancer:1.25e-4 (favourable), Liver cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 45.6 CDC73 C1orf28, FIHP, HRPT1, HRPT2, parafibromin ENSG00000134371 Cell division cycle 73 1 193122017-193253901 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016359, HPA030772 Supported Supported Nucleus
Cytosol Expressed in all Expressed in all thyroid gland: 32.0 CDH1 CD324, UVO, uvomorulin ENSG00000039068 Cadherin 1, type 1 16 68737225-68835548 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857 Supported Supported Golgi apparatus
Plasma membrane
Cell Junctions Renal cancer:2.06e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 467.0 thyroid gland: 264.7 CDK12 CRK7, CRKR, CRKRS, KIAA0904 ENSG00000167258 Cyclin-dependent kinase 12 17 39461511-39564907 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008038 Supported Supported Nucleus Expressed in all Expressed in all testis: 33.8 CDKN2A ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf ENSG00000147889 Cyclin-dependent kinase inhibitor 2A 9 21967753-21995301 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000093, CAB000445, CAB018232, HPA047838 Uncertain Validated Nucleoli Endometrial cancer:1.82e-7 (unfavourable), Renal cancer:5.76e-7 (unfavourable), Liver cancer:2.17e-4 (unfavourable), Head and neck cancer:5.19e-4 (favourable) Expressed in all Mixed parathyroid gland: 7.5 CEBPA C/EBP-alpha, CEBP ENSG00000245848 CCAAT/enhancer binding protein (C/EBP), alpha 19 33299934-33302564 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052734, HPA065037, HPA067937 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all adipose tissue: 107.9 CNOT3 KIAA0691, LENG2, NOT3, NOT3H ENSG00000088038 CCR4-NOT transcription complex, subunit 3 19 54137728-54155681 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA006408 Approved Approved Cytosol Liver cancer:2.22e-4 (unfavourable), Renal cancer:2.77e-4 (unfavourable) Expressed in all Expressed in all testis: 36.1 COL2A1 AOM, SEDC, STL1 ENSG00000139219 Collagen, type II, alpha 1 12 47972965-48004486 Cancer-related genes, Disease related genes, Predicted secreted proteins Evidence at protein level CAB002214, HPA055753 Supported Approved Nucleoplasm Mixed Group enriched 9 epididymis: 22.6;stomach: 6.0 testis: 1.6 CREBBP CBP, KAT3A, RSTS, RTS ENSG00000005339 CREB binding protein 16 3725054-3880726 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004212, HPA055861 Supported Validated Nucleoplasm
Nuclear bodies Renal cancer:6.24e-5 (favourable) Expressed in all Expressed in all testis: 60.4 CSF3R CD114, GCSFR ENSG00000119535 Colony stimulating factor 3 receptor (granulocyte) 1 36466043-36483278 Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017116, HPA048086 Supported Testis cancer:3.79e-4 (unfavourable), Renal cancer:5.72e-4 (unfavourable) Mixed Tissue enhanced appendix: 215.2;bone marrow: 243.8;placenta: 147.0 spleen: 98.2 CUX1 CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6 ENSG00000257923 Cut-like homeobox 1 7 101815904-102283957 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA003277, HPA003317 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:5.72e-7 (favourable), Glioma:9.90e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.3 CYLD CYLD1, KIAA0849, USPL2 ENSG00000083799 Cylindromatosis (turban tumor syndrome) 16 50742050-50801935 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011713, HPA050095 Approved Supported Nucleoplasm
Microtubule organizing center Expressed in all Expressed in all testis: 70.2 DAXX DAP6 ENSG00000204209 Death-domain associated protein 6 33318558-33329269 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002224, HPA008736, HPA008797, CAB025546, HPA065779 Supported Validated Nucleus
Nuclear bodies Renal cancer:6.32e-7 (unfavourable), Breast cancer:6.05e-4 (favourable) Expressed in all Mixed epididymis: 19.0 DDB2 DDBB, FLJ34321, UV-DDB2, XPE ENSG00000134574 Damage-specific DNA binding protein 2, 48kDa 11 47214465-47239240 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB025912, HPA058406 Supported Supported Nucleoplasm
Cell Junctions Endometrial cancer:1.20e-4 (favourable), Cervical cancer:1.58e-4 (favourable), Breast cancer:7.29e-4 (favourable) Expressed in all Expressed in all skin: 53.8 DICER1 Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1 ENSG00000100697 Dicer 1, ribonuclease type III 14 95086228-95158010 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000694, CAB068185 Approved Supported Cytosol Expressed in all Expressed in all placenta: 32.2 DNM2 CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII ENSG00000079805 Dynamin 2 19 10718079-10833488 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA054246 Supported Approved Golgi apparatus
Cytosol Liver cancer:3.63e-4 (unfavourable), Head and neck cancer:8.91e-4 (favourable) Expressed in all Expressed in all colon: 106.7 DNMT3A ENSG00000119772 DNA (cytosine-5-)-methyltransferase 3 alpha 2 25227855-25342590 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009469, HPA026588 Approved Supported Nucleoplasm Pancreatic cancer:1.18e-4 (favourable), Endometrial cancer:1.55e-4 (unfavourable), Liver cancer:1.58e-4 (unfavourable), Renal cancer:2.49e-4 (unfavourable) Expressed in all Expressed in all placenta: 22.6 ECT2L ARHGEF32, C6orf91, FBXO49, LFDH ENSG00000203734 Epithelial cell transforming 2 like 6 138795926-138904070 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA035488 Uncertain Not detected Tissue enriched 6 fallopian tube: 18.0 lung: 2.7 EP300 KAT3B, p300 ENSG00000100393 E1A binding protein p300 22 41091786-41180079 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB000146, HPA003128, HPA004112 Supported Validated Nucleoplasm Renal cancer:7.45e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 45.3 ERBB3 HER3, LCCS2 ENSG00000065361 Erb-b2 receptor tyrosine kinase 3 12 56079857-56103505 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB025331, HPA045396 Uncertain Approved Plasma membrane
Actin filaments Expressed in all Mixed small intestine: 88.5 ERCC2 EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD ENSG00000104884 Excision repair cross-complementation group 2 19 45349837-45370918 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005375, HPA038057, HPA069266 Approved Supported Nucleoplasm Pancreatic cancer:3.26e-4 (favourable) Expressed in all Expressed in all testis: 16.2 ERCC4 FANCQ, RAD1, XPF ENSG00000175595 Excision repair cross-complementation group 4 16 13920157-13952345 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000156, HPA045828 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Mixed testis: 10.7 ERCC5 ERCM2, XPGC ENSG00000134899 Excision repair cross-complementation group 5 13 102844844-102876001 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045845, HPA050374 Supported Approved Nucleoplasm Renal cancer:2.96e-6 (unfavourable), Urothelial cancer:6.82e-4 (favourable) Expressed in all Expressed in all spleen: 38.2 EXT1 LGCR, LGS, ttv ENSG00000182197 Exostosin glycosyltransferase 1 8 117794490-118111853 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044394 Uncertain Lung cancer:1.20e-5 (unfavourable), Thyroid cancer:4.64e-4 (unfavourable), Cervical cancer:7.04e-4 (unfavourable) Expressed in all Expressed in all duodenum: 32.5 EXT2 SOTV ENSG00000151348 Exostosin glycosyltransferase 2 11 44095549-44245429 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA078409 Supported Golgi apparatus Renal cancer:5.36e-6 (unfavourable), Head and neck cancer:2.50e-4 (unfavourable) Expressed in all Expressed in all placenta: 89.9 FANCA FA-H, FAA, FACA, FAH, FANCH ENSG00000187741 Fanconi anemia, complementation group A 16 89737549-89816657 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063236 Supported Nucleus Mixed Mixed testis: 19.5 FANCC FA3, FAC, FACC ENSG00000158169 Fanconi anemia, complementation group C 9 95099054-95317709 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017793, HPA030771 Approved Supported Nucleoplasm Renal cancer:6.03e-6 (favourable) Expressed in all Mixed testis: 18.1 FANCD2 FA-D2, FACD, FAD, FANCD ENSG00000144554 Fanconi anemia, complementation group D2 3 10026414-10101930 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016117, HPA063742 Approved Supported Nucleus
Nuclear bodies
Cytosol Ovarian cancer:5.00e-5 (unfavourable) Expressed in all Mixed testis: 21.7 FANCE FACE, FAE ENSG00000112039 Fanconi anemia, complementation group E 6 35452361-35467103 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB014893 Supported Supported Nucleoplasm Liver cancer:2.08e-9 (unfavourable), Endometrial cancer:6.25e-4 (unfavourable) Expressed in all Mixed skin: 16.2 FANCF FAF ENSG00000183161 Fanconi anemia, complementation group F 11 22622519-22626787 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:2.27e-4 (unfavourable) Expressed in all Mixed fallopian tube: 10.9 FANCG FAG, XRCC9 ENSG00000221829 Fanconi anemia, complementation group G 9 35073835-35080016 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB008105, HPA045335 Approved Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:2.38e-7 (unfavourable), Liver cancer:2.02e-4 (unfavourable) Expressed in all Mixed fallopian tube: 8.5 FBXW7 AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10 ENSG00000109670 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 4 152321259-152536101 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB013793, CAB029987 Supported Supported Nucleoplasm
Vesicles Renal cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all skin: 87.7 FH fumarase ENSG00000091483 Fumarate hydratase 1 241497603-241519761 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017785, HPA025770, HPA025948, HPA027341 Supported Approved Validated Mitochondria Renal cancer:2.76e-7 (favourable) Expressed in all Expressed in all liver: 141.9 FUBP1 FBP, FUBP ENSG00000162613 Far upstream element (FUSE) binding protein 1 1 77944055-77979110 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006149 Supported Validated Nucleoplasm Liver cancer:9.83e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 68.1 GATA3 HDR ENSG00000107485 GATA binding protein 3 10 8053604-8075198 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016217, HPA029730, HPA029731 Supported Supported Nucleoplasm Renal cancer:3.13e-4 (unfavourable) Group enriched Tissue enhanced parathyroid gland: 231.0;skin: 149.3 placenta: 44.1 GPC3 DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1 ENSG00000147257 Glypican 3 X 133535745-133985895 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006316 Approved Plasma membrane Stomach cancer:4.83e-4 (unfavourable) Expressed in all Tissue enriched 6 placenta: 838.1 lung: 130.8 GRIN2A GluN2A, NMDAR2A ENSG00000183454 Glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16 9753404-10182754 Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level CAB022725 Supported Mixed Tissue enriched 5 cerebral cortex: 25.0 testis: 4.7 KDM5C DXS1272E, JARID1C, MRX13, SMCX, XE169 ENSG00000126012 Lysine (K)-specific demethylase 5C X 53191321-53225422 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038244, HPA046147 Validated Nucleoplasm
Cytosol Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.5 KDM6A UTX ENSG00000147050 Lysine (K)-specific demethylase 6A X 44873177-45112602 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000568, HPA001165, HPA002111 Supported Approved Nucleoli Expressed in all Expressed in all bone marrow: 41.1 KLF6 BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9 ENSG00000067082 Kruppel-like factor 6 10 3775996-3785281 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB013529, HPA069585 Supported Approved Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Renal cancer:2.28e-4 (favourable) Expressed in all Expressed in all thyroid gland: 321.3 KMT2C HALR, KIAA1506, MLL3 ENSG00000055609 Lysine (K)-specific methyltransferase 2C 7 152134922-152436005 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA074736 Supported Nucleoplasm Renal cancer:8.01e-6 (favourable) Expressed in all Expressed in all skin: 25.8 KMT2D ALR, CAGL114, MLL2, MLL4, TNRC21 ENSG00000167548 Lysine (K)-specific methyltransferase 2D 12 49018975-49059774 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035977 Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 45.7 MAP2K4 JNKK1, MEK4, MKK4, PRKMK4, SERK1 ENSG00000065559 Mitogen-activated protein kinase kinase 4 17 12020824-12143830 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007751, HPA060074 Supported Approved Nucleoplasm
Cell Junctions Expressed in all Expressed in all cerebral cortex: 64.2 MAP3K1 MAPKKK1, MEKK, MEKK1 ENSG00000095015 Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 5 56815574-56896152 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB004500, HPA046509 Approved Approved Cytosol Expressed in all Mixed spleen: 28.7 MAX bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8 ENSG00000125952 MYC associated factor X 14 65006174-65102695 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000328, HPA003474 Supported Supported Nucleoplasm
Golgi apparatus
Vesicles Thyroid cancer:2.12e-4 (favourable), Renal cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 80.2 MEN1 ENSG00000133895 Multiple endocrine neoplasia I 11 64803510-64811294 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030342 Uncertain Supported Nucleoplasm
Cytosol Stomach cancer:6.31e-5 (favourable), Liver cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 22.2 MLH1 COCA2, FCC2, HNPCC, HNPCC2 ENSG00000076242 MutL homolog 1 3 36993332-37050918 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013294, HPA052707, HPA060714, CAB070868 Supported Validated Nucleoplasm Liver cancer:8.24e-5 (unfavourable) Expressed in all Expressed in all testis: 59.7 MSH2 COCA1, HNPCC, HNPCC1 ENSG00000095002 MutS homolog 2 2 47402969-47562311 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009572, CAB070867 Supported Approved Nucleoplasm
Vesicles Liver cancer:1.72e-9 (unfavourable), Endometrial cancer:4.44e-4 (unfavourable), Pancreatic cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 32.6 MSH6 GTBP ENSG00000116062 MutS homolog 6 2 47695530-47810101 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009091, HPA028376, HPA028446 Supported Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:1.06e-7 (unfavourable), Endometrial cancer:1.34e-4 (unfavourable), Liver cancer:7.86e-4 (unfavourable) Expressed in all Expressed in all ovary: 74.4 NBN AT-V1, AT-V2, ATV, NBS, NBS1 ENSG00000104320 Nibrin 8 89933336-90003228 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001429, CAB003836 Supported Approved Nucleoplasm
Golgi apparatus Lung cancer:5.46e-5 (unfavourable), Pancreatic cancer:4.20e-4 (unfavourable) Expressed in all Expressed in all appendix: 38.1 NCOR1 hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1 ENSG00000141027 Nuclear receptor corepressor 1 17 16029157-16218185 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043246, HPA050288, HPA051168, CAB072830 Supported Validated Nucleoplasm
Cytosol Renal cancer:7.92e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 84.0 NF1 ENSG00000196712 Neurofibromin 1 17 31094927-31382116 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA045502 Uncertain Approved Mitochondria Expressed in all Expressed in all parathyroid gland: 31.9 NF2 merlin ENSG00000186575 Neurofibromin 2 (merlin) 22 29603556-29698598 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003097, CAB005385 Supported Validated Nucleus
Plasma membrane
Cytosol Renal cancer:2.89e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 57.6 NOTCH2 ENSG00000134250 Notch 2 1 119911553-120069626 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046392, HPA048743 Uncertain Supported Nucleoplasm
Plasma membrane Ovarian cancer:5.24e-4 (unfavourable), Pancreatic cancer:9.48e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 46.5 PALB2 FANCN, FLJ21816 ENSG00000083093 Partner and localizer of BRCA2 16 23603160-23641310 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB014895, HPA057000 Approved Supported Nucleoplasm Pancreatic cancer:2.35e-5 (unfavourable), Colorectal cancer:2.83e-5 (favourable) Expressed in all Mixed testis: 14.4 PBRM1 BAF180, PB1 ENSG00000163939 Polybromo 1 3 52545352-52685917 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015629, HPA059373 Uncertain Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 44.5 PHF6 BFLS, BORJ, CENP-31, KIAA1823, MGC14797 ENSG00000156531 PHD finger protein 6 X 134373253-134428791 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001023 Supported Validated Nucleus
Nucleoli Liver cancer:3.38e-4 (unfavourable), Pancreatic cancer:9.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.2 PMS1 MLH2, PMSL1 ENSG00000064933 PMS1 homolog 1, mismatch repair system component 2 189784085-189877629 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010233, HPA031013 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:1.86e-6 (unfavourable), Liver cancer:2.38e-6 (unfavourable), Urothelial cancer:3.73e-4 (favourable) Expressed in all Expressed in all testis: 84.8 PMS2 HNPCC4, H_DJ0042M02.9, MLH4, PMSL2 ENSG00000122512 PMS1 homolog 2, mismatch repair system component 7 5973239-6009125 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB010235, HPA044400, HPA066490, HPA070310 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.23e-5 (favourable) Expressed in all Mixed cerebral cortex: 20.0 POT1 DKFZp586D211, hPot1 ENSG00000128513 Protection of telomeres 1 7 124822386-124929983 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA068538 Supported Nucleus Expressed in all Mixed thyroid gland: 21.5 PRDM1 BLIMP1, PRDI-BF1 ENSG00000057657 PR domain containing 1, with ZNF domain 6 106086320-106109939 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030033 Approved Approved Nucleus
Nucleoli Renal cancer:9.81e-5 (unfavourable) Expressed in all Tissue enhanced esophagus: 61.3 endometrium: 30.1 PRKAR1A CNC1, PRKAR1, TSE1 ENSG00000108946 Protein kinase, cAMP-dependent, regulatory, type I, alpha 17 68511780-68551319 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB019378, HPA049979 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 555.0 PTCH1 BCNS, NBCCS, PTCH ENSG00000185920 Patched 1 9 95442980-95517057 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013717, HPA075072 Uncertain Approved Golgi apparatus Mixed Tissue enhanced cervix, uterine: 41.6 endometrium: 27.2 PTEN BZS, MHAM, MMAC1, PTEN1, TEP1 ENSG00000171862 Phosphatase and tensin homolog 10 87863113-87971930 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004076, HPA031335 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:7.35e-4 (unfavourable) Expressed in all Mixed testis: 59.0 PTPRB PTPB ENSG00000127329 Protein tyrosine phosphatase, receptor type, B 12 70515866-70637440 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004782, HPA067868 Uncertain Approved Vesicles
Plasma membrane
Cell Junctions Renal cancer:1.02e-4 (favourable), Liver cancer:6.05e-4 (favourable) Expressed in all Mixed lung: 54.1 PTPRC CD45, GP180, LCA, T200 ENSG00000081237 Protein tyrosine phosphatase, receptor type, C 1 198638671-198757283 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000052, HPA000440, CAB002800, CAB056154, CAB068221 Supported Renal cancer:2.42e-4 (unfavourable) Expressed in all Expressed in all lymph node: 378.0 RAD21 hHR21, KIAA0078, SCC1 ENSG00000164754 RAD21 cohesin complex component 8 116845935-116874866 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020044, CAB022065 Supported Validated Nucleoplasm Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all testis: 161.7 RB1 OSRC, PPP1R130, RB ENSG00000139687 Retinoblastoma 1 13 48303751-48481986 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000095, CAB016687, HPA050082 Supported Validated Nucleoplasm Ovarian cancer:6.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.0 RECQL4 RecQ4 ENSG00000160957 RecQ helicase-like 4 8 144511288-144517845 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB017800, HPA025821 Supported Validated Nucleus Liver cancer:1.91e-4 (unfavourable) Expressed in all Mixed testis: 17.4 RET CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51 ENSG00000165731 Ret proto-oncogene 10 43077027-43130351 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002581, HPA008356, HPA008495, CAB018342 Approved Supported Supported Vesicles
Plasma membrane
Cytosol Endometrial cancer:5.02e-4 (unfavourable) Tissue enhanced Tissue enriched 5 parathyroid gland: 146.8 adrenal gland: 29.2 RNF43 DKFZp781H0392, FLJ20315, URCC ENSG00000108375 Ring finger protein 43 17 58352500-58417595 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA008079 Uncertain Renal cancer:6.04e-9 (favourable) Tissue enhanced Mixed duodenum: 24.1 RPL5 L5, PPP1R135 ENSG00000122406 Ribosomal protein L5 1 92832025-92841924 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043717 Approved Renal cancer:6.81e-5 (unfavourable) Expressed in all Expressed in all ovary: 4031.6 SDHB SDH, SDH1 ENSG00000117118 Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1 17018722-17054170 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002868, CAB009822, CAB068233, CAB068234, CAB068235 Supported Supported Nucleoplasm
Plasma membrane
Mitochondria Renal cancer:2.93e-7 (favourable) Expressed in all Expressed in all kidney: 213.3 SDHC CYB560, PGL3 ENSG00000143252 Succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1 161314257-161375340 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.20e-4 (favourable) Expressed in all Expressed in all kidney: 187.3 SDHD PGL, PGL1 ENSG00000204370 Succinate dehydrogenase complex, subunit D, integral membrane protein 11 112086773-112120013 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045727 Approved Renal cancer:1.99e-10 (favourable) Expressed in all Expressed in all kidney: 303.5 SETD2 FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A ENSG00000181555 SET domain containing 2 3 47016429-47163967 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042451 Approved Approved Nuclear speckles
Cytosol Renal cancer:7.99e-6 (favourable), Melanoma:8.19e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.5 SH2B3 IDDM20, LNK ENSG00000111252 SH2B adaptor protein 3 12 111405948-111451623 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005483 Approved Approved Nucleoplasm Renal cancer:6.20e-4 (unfavourable) Expressed in all Expressed in all spleen: 51.9 SMAD4 DPC4, MADH4 ENSG00000141646 SMAD family member 4 18 51028394-51085045 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019154 Approved Supported Nucleoplasm
Centrosome
Cytosol Renal cancer:1.92e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 38.7 SMARCA4 BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2 ENSG00000127616 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 19 10961001-11065395 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004208 Supported Supported Nucleoplasm Liver cancer:1.11e-4 (unfavourable) Expressed in all Expressed in all testis: 39.5 SMARCB1 BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1 ENSG00000099956 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 22 23786963-23834516 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009196, HPA018248, HPA019127 Supported Supported Nucleoplasm
Nucleoli fibrillar center Renal cancer:1.14e-6 (favourable), Liver cancer:6.52e-4 (unfavourable) Expressed in all Expressed in all testis: 51.2 SMARCD1 BAF60A, CRACD1, Rsc6p ENSG00000066117 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 12 50084972-50100712 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA004101 Supported Approved Nucleoplasm
Vesicles Liver cancer:2.53e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 84.7 SMARCE1 BAF57 ENSG00000073584 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 17 40624962-40648508 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003916, CAB037318 Supported Supported Nucleoplasm Expressed in all Expressed in all endometrium: 72.9 SPEN KIAA0929, MINT, RBM15C, SHARP ENSG00000065526 Spen family transcriptional repressor 1 15847864-15940460 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015825, HPA050257 Supported Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 38.3 STAG2 SA-2, SA2, SCC3B ENSG00000101972 Stromal antigen 2 X 123960212-124422664 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002857 Supported Expressed in all Expressed in all parathyroid gland: 110.6 STK11 LKB1, PJS ENSG00000118046 Serine/threonine kinase 11 19 1177558-1228435 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB016231, HPA017254, CAB022105, HPA067481 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:3.69e-5 (favourable), Head and neck cancer:1.96e-4 (favourable) Expressed in all Expressed in all testis: 70.3 TET2 FLJ20032, KIAA1546 ENSG00000168769 Tet methylcytosine dioxygenase 2 4 105145875-105279816 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043135 Supported Approved Nucleoplasm Mixed Mixed bone marrow: 15.8 TNFAIP3 A20, OTUD7C ENSG00000118503 Tumor necrosis factor, alpha-induced protein 3 6 137867188-137883312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002116 Approved Approved Centrosome
Cytosol Renal cancer:6.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 345.8 TNFRSF14 ATAR, CD270, HVEA, HVEM, LIGHTR, TR2 ENSG00000157873 Tumor necrosis factor receptor superfamily, member 14 1 2555639-2565382 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA006404, CAB026150, CAB030007 Approved Approved Cytosol
Rods & Rings Urothelial cancer:7.79e-6 (favourable), Endometrial cancer:8.01e-6 (favourable), Breast cancer:4.39e-5 (favourable) Expressed in all Expressed in all duodenum: 46.7 TP53 LFS1, p53 ENSG00000141510 Tumor protein p53 17 7661779-7687550 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level CAB002973, CAB039238, CAB039239, HPA051244, CAB072876 Supported Validated Nucleoplasm Endometrial cancer:1.35e-4 (favourable), Prostate cancer:5.01e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 50.3 TSC1 hamartin, KIAA0243, LAM, TSC ENSG00000165699 Tuberous sclerosis 1 9 132891348-132944633 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011568, CAB012481, HPA074132 Supported Validated Cytosol Liver cancer:6.03e-6 (unfavourable), Renal cancer:7.91e-4 (favourable), Pancreatic cancer:8.01e-4 (favourable) Expressed in all Expressed in all testis: 34.3 TSC2 LAM, PPP1R160, TSC4, tuberin ENSG00000103197 Tuberous sclerosis 2 16 2047465-2088720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002225, HPA030409, HPA049679 Approved Validated Cytosol Pancreatic cancer:5.06e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 35.7 UBR5 DD5, EDD, EDD1, HYD, KIAA0896 ENSG00000104517 Ubiquitin protein ligase E3 component n-recognin 5 8 102253012-102412841 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA053688 Supported Nucleoplasm
Cytosol Liver cancer:1.26e-4 (unfavourable) Expressed in all Expressed in all testis: 79.7 VHL VHL1 ENSG00000134086 Von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 3 10141008-10152220 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB005430, HPA031631, HPA031632 Uncertain Validated Nucleoplasm
Cytosol Liver cancer:1.32e-5 (unfavourable), Breast cancer:9.02e-5 (unfavourable), Stomach cancer:7.84e-4 (favourable) Expressed in all Expressed in all lymph node: 35.2 WAS IMD2, THC, WASP, WASPA ENSG00000015285 Wiskott-Aldrich syndrome X 48676596-48691427 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002022, CAB004290 Supported Renal cancer:5.58e-6 (unfavourable), Head and neck cancer:3.78e-4 (favourable), Endometrial cancer:4.95e-4 (favourable) Expressed in all Tissue enhanced appendix: 71.0;lymph node: 61.6;spleen: 70.8 bone marrow: 37.6 WRN RECQ3, RECQL2 ENSG00000165392 Werner syndrome, RecQ helicase-like 8 31033801-31173769 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028661 Approved Supported Nuclear speckles Expressed in all Mixed endometrium: 14.7 WT1 AWT1, GUD, WAGR, WIT-2 ENSG00000184937 Wilms tumor 1 11 32387775-32435630 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000327, HPA035717, HPA053848 Supported Supported Nucleoplasm Tissue enriched Tissue enhanced endometrium: 112.0;fallopian tube: 123.1;smooth muscle: 78.9 testis: 53.8 XPA XP1, XPAC ENSG00000136936 Xeroderma pigmentosum, complementation group A 9 97674909-97697357 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB000155, HPA056856 Supported Approved Nucleus
Cytokinetic bridge Renal cancer:4.28e-5 (favourable) Expressed in all Expressed in all thyroid gland: 38.9 XPC RAD4, XPCC ENSG00000154767 Xeroderma pigmentosum, complementation group C 3 14145147-14178783 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009932, HPA035707, HPA069673 Supported Validated Nucleus
Plasma membrane Renal cancer:4.14e-7 (favourable), Urothelial cancer:2.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.3