Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific ACKR1 CCBP1, CD234, DARC, Dfy, FY, GPD ENSG00000213088 Atypical chemokine receptor 1 (Duffy blood group) 1 159203307-159206500 Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA016421, HPA017672 Supported Cervical cancer:2.52e-5 (favourable), Liver cancer:1.48e-4 (favourable), Thyroid cancer:9.76e-4 (unfavourable) Expressed in all Mixed adipose tissue: 111.8 ACKR2 CCBP2, CCR10, CCR9, CMKBR9, D6 ENSG00000144648 Atypical chemokine receptor 2 3 42804752-42887974 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013819, HPA073493 Supported Supported Nucleoplasm
Vesicles
Cytosol Mixed Tissue enhanced placenta: 22.8 adipose tissue: 5.2 ACKR3 CMKOR1, CXCR7, GPR159, RDC1 ENSG00000144476 Atypical chemokine receptor 3 2 236567787-236582358 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA032003, HPA049718 Approved Supported Vesicles
Plasma membrane Renal cancer:1.76e-6 (unfavourable), Stomach cancer:2.01e-4 (unfavourable), Urothelial cancer:2.93e-4 (unfavourable), Cervical cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all placenta: 175.2 ACKR4 CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1 ENSG00000129048 Atypical chemokine receptor 4 3 132597237-132618967 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA027595 Uncertain Cytosol Mixed Mixed duodenum: 19.7 C3AR1 AZ3B, C3AR ENSG00000171860 Complement component 3a receptor 1 12 8058302-8066471 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB009405 Supported Expressed in all Tissue enhanced appendix: 88.4 placenta: 49.2 C5AR1 C5A, C5AR, C5R1, CD88 ENSG00000197405 Complement component 5a receptor 1 19 47290023-47322066 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002720, HPA014520 Approved Renal cancer:1.16e-4 (unfavourable), Cervical cancer:4.71e-4 (favourable), Testis cancer:7.99e-4 (unfavourable), Ovarian cancer:9.55e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 123.6 adipose tissue: 90.1 C5AR2 C5L2, GPR77 ENSG00000134830 Complement component 5a receptor 2 19 47332147-47347327 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA016629 Uncertain Tissue enhanced Tissue enhanced spleen: 9.9 appendix: 6.1 CCR10 GPR2 ENSG00000184451 Chemokine (C-C motif) receptor 10 17 42678889-42683917 Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011684, HPA048007, HPA069188 Uncertain Supported Endoplasmic reticulum Mixed Mixed adipose tissue: 4.5 CCR2 CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R ENSG00000121807 Chemokine (C-C motif) receptor 2 3 46353734-46360928 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB003793 Approved Lung cancer:5.87e-4 (favourable) Mixed Tissue enhanced appendix: 53.0 spleen: 20.8 CCR3 CC-CKR-3, CD193, CKR3, CMKBR3 ENSG00000183625 Chemokine (C-C motif) receptor 3 3 46163604-46266706 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB003795 Uncertain Not detected Mixed small intestine: 3.0 CCR4 CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5 ENSG00000183813 Chemokine (C-C motif) receptor 4 3 32951574-32956349 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA031613 Approved Mixed Tissue enhanced appendix: 11.8 urinary bladder: 9.2 CCR6 BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22 ENSG00000112486 Chemokine (C-C motif) receptor 6 6 167111807-167139696 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB006820, HPA014488 Approved Not detected Tissue enhanced lymph node: 20.6;tonsil: 33.8 spleen: 17.3 CCR7 BLR2, CD197, CDw197, CMKBR7, EBI1 ENSG00000126353 Chemokine (C-C motif) receptor 7 17 40553769-40565472 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB003796, HPA031383, HPA074467 Supported Supported Mitochondria Head and neck cancer:7.61e-7 (favourable), Cervical cancer:8.03e-6 (favourable), Breast cancer:3.84e-4 (favourable), Testis cancer:7.72e-4 (unfavourable) Mixed Group enriched 6 appendix: 91.9;lymph node: 98.3;spleen: 39.9;tonsil: 80.2 urinary bladder: 12.9 CCR9 CDw199, GPR-9-6, GPR28 ENSG00000173585 Chemokine (C-C motif) receptor 9 3 45886504-45903177 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB006839 Uncertain Not detected Group enriched 6 appendix: 1.5;duodenum: 3.9;small intestine: 5.8;spleen: 1.2 lymph node: 0.5 CCRL2 ACKR5, CKRX, CRAM-A, CRAM-B, HCR ENSG00000121797 Chemokine (C-C motif) receptor-like 2 3 46407163-46412997 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA043238 Approved Colorectal cancer:3.72e-5 (favourable), Urothelial cancer:9.67e-5 (favourable) Mixed Mixed lung: 17.7 CX3CR1 CCRL1, CMKBRL1, CMKDR1, GPR13, V28 ENSG00000168329 Chemokine (C-X3-C motif) receptor 1 3 39263494-39281735 Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB032478, HPA046587 Approved Tissue enhanced Tissue enhanced cerebral cortex: 59.4 spleen: 16.8 CXCR1 CD181, CDw128a, CKR-1, CMKAR1, IL8RA ENSG00000163464 Chemokine (C-X-C motif) receptor 1 2 218162845-218166995 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA031991 Uncertain Mixed Tissue enhanced appendix: 35.7;spleen: 25.4 adipose tissue: 15.5 CXCR2 CD182, CMKAR2, IL8RB ENSG00000180871 Chemokine (C-X-C motif) receptor 2 2 218125289-218137253 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB016268, HPA031999, HPA032017 Supported Mixed Tissue enhanced appendix: 56.9;spleen: 37.2 esophagus: 30.0 CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR ENSG00000186810 Chemokine (C-X-C motif) receptor 3 X 71615916-71618517 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA045942 Supported Renal cancer:1.67e-6 (unfavourable), Endometrial cancer:3.44e-6 (favourable), Melanoma:2.90e-4 (favourable), Head and neck cancer:3.35e-4 (favourable) Mixed Tissue enhanced lymph node: 18.1 spleen: 8.9 CXCR5 BLR1, CD185, MDR15 ENSG00000160683 Chemokine (C-X-C motif) receptor 5 11 118883766-118897799 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level CAB026149, HPA042432 Supported Not detected Tissue enhanced lymph node: 32.9;spleen: 21.7;tonsil: 16.2 appendix: 15.1 CXCR6 BONZO, CD186, STRL33, TYMSTR ENSG00000172215 Chemokine (C-X-C motif) receptor 6 3 45940933-45948353 CD markers, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA047591 Uncertain Endometrial cancer:6.74e-6 (favourable), Renal cancer:2.42e-5 (unfavourable), Head and neck cancer:2.16e-4 (favourable), Cervical cancer:4.92e-4 (favourable) Mixed Mixed lymph node: 17.6 FPR1 FMLP, FPR ENSG00000171051 Formyl peptide receptor 1 19 51745172-51804110 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA046550, HPA061744 Approved Approved Nucleus
Nucleoli
Golgi apparatus Renal cancer:2.21e-4 (unfavourable) Expressed in all Tissue enhanced appendix: 181.6 bone marrow: 95.2 FPR2 ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R ENSG00000171049 Formyl peptide receptor 2 19 51752026-51770526 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA029154 Approved Mixed Tissue enhanced appendix: 71.3 spleen: 20.0 XCR1 CCXCR1, GPR5 ENSG00000173578 Chemokine (C motif) receptor 1 3 46017024-46027742 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013169 Uncertain Mixed Tissue enhanced lymph node: 11.0 spleen: 9.3