105 GENES FOUNDi

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Gene

 

 

Gene description

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Protein class

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Tissue

Cell

Pathology

 

 

 

 

 

 

Subcellular location

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RNA tissue category

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HLCSHolocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
CytosolExpressed in all
IARSIsoleucyl-tRNA synthetaseEnzymes
Plasma proteins
Predicted intracellular proteins
CytosolExpressed in all
IARS2Isoleucyl-tRNA synthetase 2, mitochondrialDisease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
KARSLysyl-tRNA synthetaseDisease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
CytosolExpressed in all
LARSLeucyl-tRNA synthetaseDisease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Nuclear bodies
Cytosol
Expressed in all
LARS2Leucyl-tRNA synthetase 2, mitochondrialDisease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Mitochondria
Expressed in all
LIG1Ligase I, DNA, ATP-dependentEnzymes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Golgi apparatus
Vesicles
Mixed
LIG3Ligase III, DNA, ATP-dependentEnzymes
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
LIG4Ligase IV, DNA, ATP-dependentCancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Plasma membrane
Cytosol
Mixed
MARSMethionyl-tRNA synthetaseDisease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
CytosolExpressed in all
MARS2Methionyl-tRNA synthetase 2, mitochondrialDisease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Intermediate filaments
Cytosol
Expressed in all
MCCC1Methylcrotonoyl-CoA carboxylase 1 (alpha)Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted secreted proteins
MitochondriaExpressed in all
MCCC2Methylcrotonoyl-CoA carboxylase 2 (beta)Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
MTHFD1Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetaseDisease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
CytosolExpressed in all
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-likeEnzymes
Predicted intracellular proteins
Predicted membrane proteins
MitochondriaMixed
MTHFS5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)Enzymes
Predicted intracellular proteins
CytosolExpressed in all
NADSYN1NAD synthetase 1Enzymes
Predicted intracellular proteins
CytosolExpressed in all
NAPRTNicotinate phosphoribosyltransferaseEnzymes
Predicted intracellular proteins
Nucleus
Golgi apparatus
Cytosol
Tissue enhanced
NARSAsparaginyl-tRNA synthetaseEnzymes
Plasma proteins
Predicted intracellular proteins
CytosolExpressed in all
NARS2Asparaginyl-tRNA synthetase 2, mitochondrial (putative)Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Mitochondria
Cytosol
Expressed in all
PAICSPhosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetaseEnzymes
Plasma proteins
Predicted intracellular proteins
CytosolExpressed in all
PARS2Prolyl-tRNA synthetase 2, mitochondrial (putative)Enzymes
Predicted intracellular proteins
Nucleoli fibrillar center
Mitochondria
Mixed
PCPyruvate carboxylaseCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
PCCAPropionyl CoA carboxylase, alpha polypeptideDisease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Expressed in all
PCCBPropionyl CoA carboxylase, beta polypeptideDisease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted secreted proteins
Expressed in all
PFASPhosphoribosylformylglycinamidine synthaseEnzymes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Plasma membrane
Expressed in all
PPCSPhosphopantothenoylcysteine synthetaseEnzymes
Predicted intracellular proteins
Nucleus
Nucleoli fibrillar center
Mitochondria
Expressed in all
QARSGlutaminyl-tRNA synthetaseDisease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
CytosolExpressed in all
QRSL1Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1Enzymes
Predicted intracellular proteins
Vesicles
Centrosome
Expressed in all
RARSArginyl-tRNA synthetaseDisease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Cytosol
Expressed in all
RARS2Arginyl-tRNA synthetase 2, mitochondrialDisease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Nuclear bodies
Cytosol
Expressed in all
RIMKLARibosomal modification protein rimK-like family member AEnzymes
Predicted intracellular proteins
Nucleoli fibrillar centerTissue enhanced
RIMKLBRibosomal modification protein rimK-like family member BEnzymes
Predicted intracellular proteins
Nucleoplasm
Microtubule organizing center
Expressed in all
RTCARNA 3'-terminal phosphate cyclaseEnzymes
Predicted intracellular proteins
NucleusExpressed in all
RTCBRNA 2',3'-cyclic phosphate and 5'-OH ligaseEnzymes
Predicted intracellular proteins
Nucleoplasm
Vesicles
Cytosol
Expressed in all
SARSSeryl-tRNA synthetaseEnzymes
Plasma proteins
Predicted intracellular proteins
CytosolExpressed in all
SARS2Seryl-tRNA synthetase 2, mitochondrialDisease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Expressed in all
SLC27A2Solute carrier family 27 (fatty acid transporter), member 2Enzymes
Predicted membrane proteins
Transporters
Group enriched
SLC27A5Solute carrier family 27 (fatty acid transporter), member 5Enzymes
Predicted intracellular proteins
Predicted membrane proteins
Transporters
Tissue enriched
SUCLA2Succinate-CoA ligase, ADP-forming, beta subunitCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
SUCLG1Succinate-CoA ligase, alpha subunitCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted secreted proteins
Plasma membrane
Mitochondria
Expressed in all
SUCLG2Succinate-CoA ligase, GDP-forming, beta subunitCitric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
Plasma membrane
Mitochondria
Expressed in all
TARSThreonyl-tRNA synthetaseEnzymes
Plasma proteins
Predicted intracellular proteins
Actin filaments
Cytosol
Expressed in all
TARS2Threonyl-tRNA synthetase 2, mitochondrial (putative)Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Intermediate filaments
Cytosol
Expressed in all
TARSL2Threonyl-tRNA synthetase-like 2Enzymes
Predicted intracellular proteins
CytosolExpressed in all
TRIM25Tripartite motif containing 25Cancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Nuclear bodies
Cytosol
Expressed in all
TTLTubulin tyrosine ligaseCancer-related genes
Enzymes
Predicted intracellular proteins
Nucleoplasm
Vesicles
Mixed
UBA1Ubiquitin-like modifier activating enzyme 1Cancer-related genes
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
NucleoplasmExpressed in all
UBA6Ubiquitin-like modifier activating enzyme 6Enzymes
Predicted intracellular proteins
Nucleoplasm
Cytosol
Expressed in all
VARSValyl-tRNA synthetaseEnzymes
Plasma proteins
Predicted intracellular proteins
CytosolMixed

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