Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific BBX HBP2, HSPC339, MDS001 ENSG00000114439 Bobby sox homolog (Drosophila) 3 107522936-107811324 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006049, HPA050646 Supported Validated Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 115.3 CIC KIAA0306 ENSG00000079432 Capicua transcriptional repressor 19 42268537-42295797 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026388, HPA044341, HPA064725 Approved Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 55.0 HBP1 ENSG00000105856 HMG-box transcription factor 1 7 107168961-107202529 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020225, CAB032824 Approved Validated Nuclear speckles Renal cancer:7.70e-5 (favourable) Expressed in all Expressed in all thyroid gland: 108.7 HMG20A FLJ10739, HMGX1, HMGXB1 ENSG00000140382 High mobility group 20A 15 77420412-77485607 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008126 Supported Approved Nucleus Expressed in all Expressed in all spleen: 49.8 HMG20B BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL ENSG00000064961 High mobility group 20B 19 3572777-3579088 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050220, HPA053157, HPA069832 Approved Validated Nucleoplasm Endometrial cancer:1.72e-7 (favourable), Urothelial cancer:2.89e-5 (favourable) Expressed in all Expressed in all prostate: 64.9 HMGXB3 HMGX3, KIAA0194, SMF ENSG00000113716 HMG box domain containing 3 5 150000046-150053142 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005967 Approved Nucleoli Liver cancer:3.37e-5 (unfavourable) Expressed in all Tissue enriched 11 parathyroid gland: 278.2 prostate: 26.2 HMGXB4 HMG2L1, THC211630 ENSG00000100281 HMG box domain containing 4 22 35257452-35295807 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000725 Approved Colorectal cancer:3.24e-5 (favourable), Pancreatic cancer:1.16e-4 (unfavourable), Liver cancer:4.79e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.7 LEF1 TCF10, TCF1ALPHA, TCF7L3 ENSG00000138795 Lymphoid enhancer-binding factor 1 4 108047545-108168956 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002087, CAB019405 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.47e-6 (unfavourable), Endometrial cancer:1.37e-5 (favourable) Expressed in all Tissue enhanced lymph node: 42.2 tonsil: 29.3 NFYA CBF-B, HAP2, NF-YA ENSG00000001167 Nuclear transcription factor Y, alpha 6 41072945-41099976 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009250, HPA050779 Supported Supported Nucleoplasm Liver cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all testis: 71.0 NFYB CBF-A, HAP3, NF-YB ENSG00000120837 Nuclear transcription factor Y, beta 12 104117077-104138289 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004211 Supported Supported Nucleoplasm Renal cancer:9.28e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 122.9 NFYC CBF-C, NF-YC ENSG00000066136 Nuclear transcription factor Y, gamma 1 40691570-40771603 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055011 Supported Nucleoplasm Renal cancer:1.24e-4 (favourable), Liver cancer:7.24e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 60.0 PBRM1 BAF180, PB1 ENSG00000163939 Polybromo 1 3 52545352-52685917 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015629, HPA059373 Uncertain Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 44.5 SMARCE1 BAF57 ENSG00000073584 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 17 40624962-40648508 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003916, CAB037318 Supported Supported Nucleoplasm Expressed in all Expressed in all endometrium: 72.9 SOX1 ENSG00000182968 SRY (sex determining region Y)-box 1 13 112067647-112070488 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Group enriched Group enriched 8 cerebral cortex: 3.6;testis: 1.5 skin: 0.3 SOX10 DOM, WS2E, WS4 ENSG00000100146 SRY (sex determining region Y)-box 10 22 37970686-37987422 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003171, HPA068898 Supported Supported Nucleoplasm Not detected Tissue enhanced cerebral cortex: 56.8;salivary gland: 50.8 breast: 24.0 SOX11 ENSG00000176887 SRY (sex determining region Y)-box 11 2 5692667-5701385 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000536, CAB056152, CAB056153 Approved Group enriched Tissue enriched 14 cerebral cortex: 5.4 smooth muscle: 0.3 SOX12 SOX22 ENSG00000177732 SRY (sex determining region Y)-box 12 20 325401-330224 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055052, HPA061627 Supported Nucleoplasm Liver cancer:6.64e-5 (unfavourable) Expressed in all Mixed cerebral cortex: 10.3 SOX13 ICA12, MGC117216, Sox-13 ENSG00000143842 SRY (sex determining region Y)-box 13 1 204073115-204127743 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051790, HPA054843 Validated Nucleoplasm Colorectal cancer:6.49e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 52.4 SOX14 SOX28 ENSG00000168875 SRY (sex determining region Y)-box 14 3 137764284-137766338 Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Group enriched 18 placenta: 2.4;prostate: 1.1 testis: 0.1 SOX15 SOX20, SOX26, SOX27 ENSG00000129194 SRY (sex determining region Y)-box 15 17 7588178-7590170 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067196, HPA074049 Supported Supported Nucleus
Nucleoli
Golgi apparatus
Vesicles Tissue enhanced Tissue enhanced skin: 40.6 esophagus: 17.5 SOX17 ENSG00000164736 SRY (sex determining region Y)-box 17 8 54457935-54460888 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025594, HPA068399 Supported Approved Nucleoplasm Endometrial cancer:2.76e-4 (favourable) Group enriched Tissue enhanced cervix, uterine: 30.1;endometrium: 32.1;fallopian tube: 30.1 adipose tissue: 14.7 SOX18 ENSG00000203883 SRY (sex determining region Y)-box 18 20 64047582-64049641 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA073703 Approved Nucleus Expressed in all Tissue enhanced adipose tissue: 32.9 lung: 12.0 SOX2 ENSG00000181449 SRY (sex determining region Y)-box 2 3 181711924-181714436 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB010648, HPA045725 Approved Supported Nucleoplasm Tissue enhanced Tissue enriched 8 cerebral cortex: 118.3 esophagus: 14.9 SOX21 SOX25 ENSG00000125285 SRY (sex determining region Y)-box 21 13 94709622-94712399 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA064084 Approved Nucleus Glioma:1.34e-4 (favourable), Cervical cancer:7.60e-4 (favourable) Tissue enhanced Group enriched 6 cerebral cortex: 18.0;esophagus: 6.9;skin: 19.4;stomach: 33.9 tonsil: 3.2 SOX3 PHP ENSG00000134595 SRY (sex determining region Y)-box 3 X 140502987-140505503 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054720, HPA075003 Validated Nucleoplasm Tissue enhanced Tissue enriched 7 fallopian tube: 11.7 testis: 1.7 SOX30 ENSG00000039600 SRY (sex determining region Y)-box 30 5 157625679-157671480 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006159, CAB009382 Supported Mixed Tissue enriched 90 testis: 144.0 fallopian tube: 1.6 SOX4 ENSG00000124766 SRY (sex determining region Y)-box 4 6 21592769-21598619 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029901 Approved Supported Nucleoplasm
Mitochondria Liver cancer:2.57e-5 (unfavourable) Expressed in all Expressed in all endometrium: 80.4 SOX5 L-SOX5, MGC35153 ENSG00000134532 SRY (sex determining region Y)-box 5 12 23529500-23951032 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060499 Supported Nucleoplasm Mixed Tissue enhanced testis: 58.3 cerebral cortex: 11.7 SOX6 ENSG00000110693 SRY (sex determining region Y)-box 6 11 15966449-16739591 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001923, HPA003908 Approved Approved Nucleoplasm Renal cancer:6.47e-12 (favourable) Mixed Tissue enhanced testis: 25.8 bone marrow: 16.6 SOX7 ENSG00000171056 SRY (sex determining region Y)-box 7 8 10723768-10730512 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009065 Approved Approved Nuclear speckles
Golgi apparatus Expressed in all Tissue enhanced placenta: 49.2 lung: 18.7 SOX8 ENSG00000005513 SRY (sex determining region Y)-box 8 16 981808-986979 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041640, HPA058665 Approved Supported Nucleus Tissue enriched Tissue enriched 29 cerebral cortex: 110.2 salivary gland: 3.8 SOX9 CMD1, CMPD1, SRA1 ENSG00000125398 SRY (sex determining region Y)-box 9 17 72121020-72126420 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001758, CAB022456, CAB068240 Supported Validated Nucleoplasm Lung cancer:2.07e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 61.5 SRY TDF ENSG00000184895 Sex determining region Y Y 2786855-2787699 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level Tissue enhanced Tissue enhanced skin: 1.0;testis: 2.8 esophagus: 0.7 SSRP1 FACT80 ENSG00000149136 Structure specific recognition protein 1 11 57325985-57335877 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002697 Approved Approved Nucleus
Cytosol Liver cancer:4.03e-7 (unfavourable), Pancreatic cancer:1.40e-4 (unfavourable), Renal cancer:5.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 122.9 TAF1 BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250 ENSG00000147133 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa X 71366239-71532374 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001075, CAB016283 Supported Validated Nucleoplasm Renal cancer:6.03e-4 (unfavourable), Lung cancer:6.54e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 25.7 TCF7 TCF-1 ENSG00000081059 Transcription factor 7 (T-cell specific, HMG-box) 5 134114711-134151865 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019403, HPA058863, HPA070505 Supported Validated Nucleoplasm Expressed in all Tissue enhanced lymph node: 111.6 appendix: 74.8 TCF7L1 TCF3 ENSG00000152284 Transcription factor 7-like 1 (T-cell specific, HMG-box) 2 85133410-85310388 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071298 Supported Nucleoplasm
Cytosol Liver cancer:6.16e-5 (unfavourable), Endometrial cancer:1.70e-4 (unfavourable), Renal cancer:2.06e-4 (unfavourable), Stomach cancer:2.72e-4 (unfavourable), Urothelial cancer:5.38e-4 (unfavourable) Expressed in all Mixed adipose tissue,endometrium: 22.8 TCF7L2 TCF-4, TCF4 ENSG00000148737 Transcription factor 7-like 2 (T-cell specific, HMG-box) 10 112950250-113167678 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB013535, HPA038800 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all endometrium: 33.6 TFAM TCF6, TCF6L2 ENSG00000108064 Transcription factor A, mitochondrial 10 58385022-58399221 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA040648, HPA063684 Supported Validated Mitochondria Renal cancer:2.22e-5 (favourable), Ovarian cancer:2.74e-4 (favourable), Endometrial cancer:8.73e-4 (unfavourable) Expressed in all Expressed in all testis: 62.0 TOX KIAA0808, TOX1 ENSG00000198846 Thymocyte selection-associated high mobility group box 8 58805418-59119208 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018322, HPA073241 Supported Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.90e-7 (unfavourable), Lung cancer:5.20e-4 (favourable) Expressed in all Mixed lymph node: 21.3 TOX2 C20orf100, dJ1108D11.2, GCX-1 ENSG00000124191 TOX high mobility group box family member 2 20 43914864-44069616 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049900, HPA058396 Approved Supported Nucleoplasm Renal cancer:7.45e-8 (unfavourable), Endometrial cancer:2.60e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 19.5 TOX3 CAGF9, TNRC9 ENSG00000103460 TOX high mobility group box family member 3 16 52438005-52547802 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040376 Approved Approved Nucleoplasm Renal cancer:3.08e-12 (favourable), Urothelial cancer:3.95e-4 (favourable) Mixed Mixed stomach: 18.0 TOX4 C14orf92, KIAA0737, LCP1 ENSG00000092203 TOX high mobility group box family member 4 14 21476597-21499175 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017880, HPA027551 Approved Approved Nucleus
Nucleoli
Vesicles Renal cancer:8.38e-5 (favourable), Liver cancer:3.46e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.8 UBTF NOR-90, UBF, UBF1, UBF2 ENSG00000108312 Upstream binding transcription factor, RNA polymerase I 17 44205033-44221626 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004611, HPA006385 Supported Supported Validated Nucleoli fibrillar center Expressed in all Expressed in all lymph node: 82.3 UBTFL1 C11orf27 ENSG00000255009 Upstream binding transcription factor, RNA polymerase I-like 1 11 90085950-90087131 Predicted intracellular proteins, Transcription factors No evidence Not detected Not detected all non-specific tissues: 0.0 WHSC1 MMSET, NSD2 ENSG00000109685 Wolf-Hirschhorn syndrome candidate 1 4 1871424-1982207 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015801, CAB068246, CAB068247 Supported Supported Nucleus Liver cancer:2.61e-4 (unfavourable), Renal cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all testis: 66.9