Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific MCOLN1 ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1 ENSG00000090674 Mucolipin 1 19 7522626-7534009 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA031763, CAB032637 Uncertain Supported Plasma membrane
Cytosol Pancreatic cancer:5.60e-5 (favourable), Renal cancer:5.67e-4 (favourable) Expressed in all Expressed in all spleen: 49.0 MCOLN2 FLJ36691, TRP-ML2, TRPML2 ENSG00000153898 Mucolipin 2 1 84925583-84997113 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA019114, HPA048999 Uncertain Supported Intermediate filaments Lung cancer:2.56e-4 (favourable) Mixed Mixed rectum: 17.6 MCOLN3 FLJ11006, TRP-ML3, TRPML3 ENSG00000055732 Mucolipin 3 1 85018082-85048499 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA018106, HPA062137 Approved Approved Nucleoli
Cytosol Tissue enriched Tissue enhanced adrenal gland: 57.9;parathyroid gland: 42.1 epididymis: 17.3 PKD2 Pc-2, PC2, PKD4, TRPP2 ENSG00000118762 Polycystic kidney disease 2 (autosomal dominant) 4 88007668-88077777 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB004544, HPA015794 Approved Validated Endoplasmic reticulum Expressed in all Expressed in all endometrium: 100.4 PKD2L1 PCL, PKD2L, PKDL, TRPP3 ENSG00000107593 Polycystic kidney disease 2-like 1 10 100288154-100330486 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB022621 Uncertain Mixed Tissue enhanced spleen: 10.0 lung: 3.4 PKD2L2 TRPP5 ENSG00000078795 Polycystic kidney disease 2-like 2 5 137887968-137942747 Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level HPA041903, HPA043634 Approved Approved Plasma membrane
Cytosol Not detected Tissue enriched 11 testis: 15.6 thyroid gland: 1.4 TRPA1 ANKTM1 ENSG00000104321 Transient receptor potential cation channel, subfamily A, member 1 8 72019917-72075617 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA026630 Uncertain Colorectal cancer:6.57e-4 (favourable) Mixed Tissue enhanced urinary bladder: 30.5 gallbladder: 11.4 TRPC1 HTRP-1 ENSG00000144935 Transient receptor potential cation channel, subfamily C, member 1 3 142724074-142807888 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB009387, HPA021130 Supported Approved Vesicles Renal cancer:2.72e-5 (unfavourable) Mixed Mixed endometrium: 18.5 TRPC3 ENSG00000138741 Transient receptor potential cation channel, subfamily C, member 3 4 121879027-121951754 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA037969 Uncertain Not detected Tissue enhanced smooth muscle: 4.1 cerebral cortex: 2.1 TRPC4 HTRP4, TRP4 ENSG00000133107 Transient receptor potential cation channel, subfamily C, member 4 13 37636636-37870425 Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Mixed Tissue enhanced endometrium: 18.5;seminal vesicle: 12.0;smooth muscle: 18.2 prostate: 10.7 TRPC5 PPP1R159 ENSG00000072315 Transient receptor potential cation channel, subfamily C, member 5 X 111774315-112082776 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Group enriched Tissue enhanced cerebral cortex: 1.9 liver: 0.4 TRPC6 FSGS2, TRP6 ENSG00000137672 Transient receptor potential cation channel, subfamily C, member 6 11 101451564-101872562 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA045098, HPA062164 Approved Approved Nucleoplasm
Cytosol Mixed Tissue enhanced placenta: 29.8 lung: 20.0 TRPC7 ENSG00000069018 Transient receptor potential cation channel, subfamily C, member 7 5 136213320-136365537 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level CAB022592, HPA031126 Uncertain Uncertain Actin filaments
Focal adhesion sites Not detected Not detected testis: 0.7 TRPM1 CSNB1C, LTRPC1, MLSN1 ENSG00000134160 Transient receptor potential cation channel, subfamily M, member 1 15 31001061-31161273 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA014779, HPA014785 Approved Uncertain Nucleoplasm
Cytosol Tissue enriched Group enriched 27 skin: 4.8;testis: 2.5 kidney: 0.1 TRPM3 GON-2, KIAA1616, LTRPC3 ENSG00000083067 Transient receptor potential cation channel, subfamily M, member 3 9 70529063-71446904 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enhanced kidney: 17.5 testis: 6.3 TRPM4 FLJ20041 ENSG00000130529 Transient receptor potential cation channel, subfamily M, member 4 19 49157741-49211836 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA041169 Supported Supported Nucleoplasm
Plasma membrane Renal cancer:2.53e-7 (favourable), Endometrial cancer:2.88e-7 (favourable) Expressed in all Mixed colon: 27.5 TRPM5 LTRPC5, MTR1 ENSG00000070985 Transient receptor potential cation channel, subfamily M, member 5 11 2404515-2423045 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA042115, HPA043315 Approved Tissue enhanced Group enriched 5 colon: 1.0;duodenum: 3.0;epididymis: 2.2;seminal vesicle: 2.5;small intestine: 2.9 testis,thyroid gland: 0.4 TRPM6 CHAK2, FLJ22628, HOMG, HSH ENSG00000119121 Transient receptor potential cation channel, subfamily M, member 6 9 74722495-74888094 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Tissue enhanced Tissue enhanced colon: 13.3;rectum: 18.5 small intestine: 8.9 TRPM7 CHAK1, LTRPC7, TRP-PLIK ENSG00000092439 Transient receptor potential cation channel, subfamily M, member 7 15 50552473-50686815 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA035523, HPA052173 Uncertain Approved Nucleoplasm Expressed in all Tissue enriched 7 parathyroid gland: 212.8 thyroid gland: 29.0 TRPM8 ENSG00000144481 Transient receptor potential cation channel, subfamily M, member 8 2 233917398-234019522 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level Liver cancer:7.15e-4 (favourable) Tissue enriched Tissue enriched 8 prostate: 128.7 liver: 16.3 TRPV1 VR1 ENSG00000196689 Transient receptor potential cation channel, subfamily V, member 1 17 3565444-3609411 FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level Not detected Mixed duodenum: 8.0 TRPV4 CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC ENSG00000111199 Transient receptor potential cation channel, subfamily V, member 4 12 109783085-109833401 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA007150 Uncertain Renal cancer:4.12e-5 (favourable), Ovarian cancer:8.10e-4 (unfavourable) Expressed in all Mixed kidney: 11.8 TRPV5 CaT2, ECAC1 ENSG00000127412 Transient receptor potential cation channel, subfamily V, member 5 7 142908101-142933808 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA063175 Approved Not detected Not detected kidney: 0.5 TRPV6 CaT1, ECAC2 ENSG00000165125 Transient receptor potential cation channel, subfamily V, member 6 7 142871203-142885762 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA062864 Approved Tissue enriched Tissue enhanced prostate: 38.7;salivary gland: 29.3 placenta: 17.4