Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific KCNK1 DPK, K2p1.1, TWIK-1 ENSG00000135750 Potassium channel, two pore domain subfamily K, member 1 1 233614004-233672512 Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA016049, CAB022588 Approved Approved Vesicles Renal cancer:8.69e-8 (unfavourable), Liver cancer:3.84e-4 (favourable), Pancreatic cancer:7.29e-4 (unfavourable) Mixed Mixed cerebral cortex: 46.6 KCNK13 K2p13.1, THIK-1, THIK1 ENSG00000152315 Potassium channel, two pore domain subfamily K, member 13 14 90061765-90185857 Predicted membrane proteins, Voltage-gated ion channels Evidence at transcript level HPA003514 Approved Approved Nuclear speckles
Cell Junctions Mixed Tissue enhanced parathyroid gland: 14.3;testis: 14.4 kidney: 3.3 KCNK15 dJ781B1.1, K2p15.1, KCNK11, KCNK14, KIAA0237, KT3.3, TASK-5, TASK5 ENSG00000124249 Potassium channel, two pore domain subfamily K, member 15 20 44745780-44752313 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA064861 Uncertain Cervical cancer:3.68e-4 (unfavourable) Tissue enriched Tissue enhanced fallopian tube: 8.0 testis: 2.9 KCNK17 K2p17.1, TALK-2, TALK2, TASK-4, TASK4 ENSG00000124780 Potassium channel, two pore domain subfamily K, member 17 6 39299001-39314553 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at transcript level HPA043892 Uncertain Mixed Tissue enhanced lung: 5.6 placenta: 5.2 KCNK18 K2p18.1, TRESK, TRESK-2, TRESK2, TRIK ENSG00000186795 Potassium channel, two pore domain subfamily K, member 18 10 117197489-117210299 Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA044739 Uncertain Not detected Not detected testis: 0.2 KCNK2 K2p2.1, TREK-1 ENSG00000082482 Potassium channel, two pore domain subfamily K, member 2 1 215005775-215237093 FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels Evidence at protein level HPA056054 Uncertain Approved Mitochondria
Cytosol Mixed Tissue enhanced adrenal gland: 75.5 thyroid gland: 17.3 KCNK5 K2p5.1, TASK-2 ENSG00000164626 Potassium channel, two pore domain subfamily K, member 5 6 39188973-39229450 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA059148 Uncertain Approved Nucleus Renal cancer:4.98e-7 (favourable), Cervical cancer:3.29e-4 (favourable), Urothelial cancer:4.45e-4 (favourable), Pancreatic cancer:5.85e-4 (unfavourable) Mixed Tissue enhanced small intestine: 40.1 gallbladder: 29.6 KCNK6 K2p6.1, TWIK-2 ENSG00000099337 Potassium channel, two pore domain subfamily K, member 6 19 38319844-38332076 Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB022637, HPA040184 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Endometrial cancer:1.45e-6 (favourable), Renal cancer:1.04e-5 (unfavourable) Expressed in all Mixed endometrium: 22.8 KCNK7 K2p7.1 ENSG00000173338 Potassium channel, two pore domain subfamily K, member 7 11 65592855-65595996 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Voltage-gated ion channels Evidence at transcript level HPA077577 Approved Plasma membrane Tissue enhanced Tissue enriched 7 skin: 53.1 esophagus: 8.0