Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific ABCA7 ABCX ENSG00000064687 ATP-binding cassette, sub-family A (ABC1), member 7 19 1040101-1065572 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041564 Supported Supported Golgi apparatus
Plasma membrane
Cell Junctions Endometrial cancer:1.12e-4 (favourable), Colorectal cancer:7.26e-4 (unfavourable) Expressed in all Mixed spleen: 25.8 ABCC5 EST277145, MOAT-C, MRP5, SMRP ENSG00000114770 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3 183919934-184018015 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA044067, HPA052295 Uncertain Supported Nucleus
Plasma membrane
Cell Junctions Liver cancer:6.78e-8 (unfavourable), Prostate cancer:3.40e-4 (unfavourable) Expressed in all Expressed in all stomach: 72.0 ABLIM3 KIAA0843 ENSG00000173210 Actin binding LIM protein family, member 3 5 149141483-149260542 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003245 Approved Approved Nucleoplasm
Plasma membrane
Cell Junctions Renal cancer:1.28e-4 (unfavourable) Mixed Tissue enhanced parathyroid gland: 78.1 adipose tissue: 63.4 AGER RAGE ENSG00000204305 Advanced glycosylation end product-specific receptor 6 32180968-32184324 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB011682, HPA064436 Approved Approved Nucleoli fibrillar center
Plasma membrane
Cell Junctions Renal cancer:9.01e-7 (unfavourable), Urothelial cancer:2.74e-6 (favourable), Pancreatic cancer:3.41e-4 (favourable) Expressed in all Tissue enriched 181 lung: 891.2 thyroid gland: 4.9 ARHGAP21 ARHGAP10, KIAA1424 ENSG00000107863 Rho GTPase activating protein 21 10 24583609-24723668 Predicted intracellular proteins Evidence at protein level HPA036610, HPA057861 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Expressed in all Expressed in all cerebral cortex: 103.8 ARL15 ARFRP2, FLJ20051 ENSG00000185305 ADP-ribosylation factor-like 15 5 53883945-54310582 Predicted intracellular proteins Evidence at protein level HPA044604, HPA063820 Uncertain Approved Golgi apparatus
Plasma membrane
Cell Junctions Expressed in all Expressed in all placenta: 44.4 ARVCF ENSG00000099889 Armadillo repeat gene deleted in velocardiofacial syndrome 22 19969896-20016808 Predicted intracellular proteins Evidence at protein level CAB016162, HPA055264, HPA063675 Approved Supported Nuclear speckles
Plasma membrane
Cell Junctions Urothelial cancer:5.76e-6 (favourable) Expressed in all Mixed spleen: 9.0 C8orf37 CORD16, FLJ30600, RP64 ENSG00000156172 Chromosome 8 open reading frame 37 8 95244919-95269201 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024198 Approved Approved Plasma membrane
Cell Junctions
Cytosol Endometrial cancer:4.63e-4 (unfavourable) Expressed in all Mixed fallopian tube: 6.3 CAMK2G CAMKG ENSG00000148660 Calcium/calmodulin-dependent protein kinase II gamma 10 73812501-73874591 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040656, HPA051783, HPA051785, HPA053973 Approved Approved Plasma membrane
Cell Junctions
Cytosol Expressed in all Expressed in all cerebral cortex: 119.4 CCDC66 DKFZp686C0433 ENSG00000180376 Coiled-coil domain containing 66 3 56557161-56621818 Predicted intracellular proteins Evidence at protein level HPA044185 Uncertain Approved Cell Junctions
Midbody ring
Microtubule organizing center Expressed in all Mixed fallopian tube: 9.5 CD34 ENSG00000174059 CD34 molecule 1 207880972-207911402 CD markers, Predicted membrane proteins Evidence at protein level CAB000018, HPA036722, HPA036723 Supported Approved Nucleus
Plasma membrane
Cell Junctions Head and neck cancer:5.93e-5 (favourable), Renal cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all placenta: 313.8 CDH1 CD324, UVO, uvomorulin ENSG00000039068 Cadherin 1, type 1 16 68737225-68835548 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857 Supported Supported Golgi apparatus
Plasma membrane
Cell Junctions Renal cancer:2.06e-4 (favourable) Expressed in all Tissue enhanced parathyroid gland: 467.0 thyroid gland: 264.7 CERCAM CEECAM1, CerCAM, GLT25D3 ENSG00000167123 Cerebral endothelial cell adhesion molecule 9 128411751-128437351 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021657, HPA051595 Uncertain Approved Nucleus
Nucleoli
Cell Junctions Renal cancer:3.33e-16 (unfavourable), Urothelial cancer:3.30e-5 (unfavourable), Ovarian cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 156.0 COLEC12 CL-P1, SCARA4, SRCL ENSG00000158270 Collectin sub-family member 12 18 316740-500722 Predicted membrane proteins Evidence at protein level HPA047917, HPA071056 Supported Approved Golgi apparatus
Vesicles
Cell Junctions Thyroid cancer:8.10e-4 (unfavourable) Expressed in all Tissue enhanced placenta: 28.2 lung: 16.7 CTNNBIP1 ICAT, MGC15093 ENSG00000178585 Catenin, beta interacting protein 1 1 9848276-9910336 Predicted intracellular proteins Evidence at protein level HPA042617 Approved Plasma membrane
Cell Junctions
Mitochondria Endometrial cancer:5.68e-6 (favourable) Expressed in all Expressed in all skin: 288.8 CTNND2 GT24, NPRAP ENSG00000169862 Catenin (cadherin-associated protein), delta 2 5 10971840-11904043 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015077, CAB037339 Supported Approved Nucleoplasm
Golgi apparatus
Cell Junctions Tissue enriched Tissue enriched 18 cerebral cortex: 103.5 spleen: 5.7 CTXN1 FLJ25968 ENSG00000178531 Cortexin 1 19 7924485-7926166 Predicted membrane proteins Evidence at transcript level HPA016669 Uncertain Approved Nucleoplasm
Plasma membrane
Cell Junctions Expressed in all Tissue enhanced cerebral cortex: 100.8 endometrium: 22.7 CYP20A1 CYP-M ENSG00000119004 Cytochrome P450, family 20, subfamily A, polypeptide 1 2 203238449-203305840 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055872, HPA058461 Uncertain Approved Plasma membrane
Cell Junctions
Actin filaments Expressed in all Mixed thyroid gland: 18.7 DCP2 NUDT20 ENSG00000172795 Decapping mRNA 2 5 112976702-113020970 Enzymes, Predicted intracellular proteins Evidence at protein level CAB011677, HPA057676 Approved Approved Nucleoplasm
Cell Junctions
Cytoplasmic bodies Renal cancer:2.66e-5 (unfavourable), Liver cancer:4.84e-4 (unfavourable) Expressed in all Mixed placenta: 18.8 DHRS7B CGI-93, DKFZp566O084, MGC8916, SDR32C1 ENSG00000109016 Dehydrogenase/reductase (SDR family) member 7B 17 21123364-21193265 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012132, HPA016873 Uncertain Approved Plasma membrane
Cell Junctions
Cytosol Endometrial cancer:1.98e-8 (favourable), Renal cancer:3.95e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 49.4 DLX1 ENSG00000144355 Distal-less homeobox 1 2 172084740-172089677 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA035666, HPA045884 Approved Approved Nucleus
Vesicles
Cell Junctions Tissue enhanced Tissue enhanced adrenal gland: 1.6;cerebral cortex: 5.0 prostate: 0.7 DOC2A ENSG00000149927 Double C2-like domains, alpha 16 30005509-30023270 Predicted intracellular proteins Evidence at protein level HPA065676 Uncertain Nucleus
Nucleoli
Cell Junctions Tissue enhanced Group enriched 9 cerebral cortex: 69.9;testis: 21.0 ovary: 5.2 DONSON B17, C21orf60, C2TA, DKFZP434M035 ENSG00000159147 Downstream neighbor of SON 21 33559542-33588708 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039558, HPA049033 Uncertain Approved Nucleoplasm
Cell Junctions
Cytosol Renal cancer:0.00e+0 (unfavourable), Ovarian cancer:2.17e-4 (favourable), Liver cancer:8.22e-4 (unfavourable) Expressed in all Tissue enhanced testis: 40.2 parathyroid gland: 15.4 DTNA D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3 ENSG00000134769 Dystrobrevin, alpha 18 34493290-34891844 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB015196, HPA071177 Supported Approved Nucleoplasm
Cell Junctions
Intermediate filaments Renal cancer:2.64e-7 (favourable) Tissue enriched Tissue enhanced cerebral cortex: 197.7 heart muscle: 100.9 EPB41 4.1R, EL1 ENSG00000159023 Erythrocyte membrane protein band 4.1 1 28887091-29120046 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA028076, HPA028412, HPA028414 Supported Supported Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.75e-6 (unfavourable), Endometrial cancer:4.58e-4 (unfavourable), Head and neck cancer:5.87e-4 (favourable) Expressed in all Expressed in all lymph node: 51.3 EPB41L2 4.1-G ENSG00000079819 Erythrocyte membrane protein band 4.1-like 2 6 130839347-131063322 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005730, HPA006642 Supported Validated Nucleus
Plasma membrane
Cell Junctions Liver cancer:2.41e-5 (unfavourable), Ovarian cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 139.6 FAAP20 C1orf86, FLJ31031 ENSG00000162585 Fanconi anemia core complex associated protein 20 1 2184461-2212720 Predicted intracellular proteins Evidence at protein level HPA038829 Uncertain Supported Nucleoplasm
Nuclear bodies
Cell Junctions Pancreatic cancer:2.88e-4 (favourable), Liver cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 13.2 FAM13A ARHGAP48, FAM13A1, KIAA0914 ENSG00000138640 Family with sequence similarity 13, member A 4 88725955-89111398 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038108, HPA038109 Uncertain Approved Nucleoli
Cell Junctions
Cytosol Urothelial cancer:4.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 113.3 FBLIM1 CAL, FBLP-1, migfilin ENSG00000162458 Filamin binding LIM protein 1 1 15756607-15786594 Predicted intracellular proteins Evidence at protein level HPA025287, HPA072750 Approved Supported Nucleoli fibrillar center
Cell Junctions
Focal adhesion sites Cervical cancer:4.07e-4 (unfavourable), Melanoma:6.15e-4 (unfavourable), Renal cancer:8.64e-4 (unfavourable) Expressed in all Mixed gallbladder: 102.3 FLT4 PCL, VEGFR3 ENSG00000037280 Fms-related tyrosine kinase 4 5 180601506-180649624 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB000099 Supported Nuclear speckles
Plasma membrane
Cell Junctions Expressed in all Mixed spleen: 18.6 GIPC1 C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2 ENSG00000123159 GIPC PDZ domain containing family, member 1 19 14477760-14496149 Predicted intracellular proteins Evidence at protein level HPA043958, HPA061786 Approved Approved Nucleus
Plasma membrane
Cell Junctions Expressed in all Expressed in all esophagus: 104.4 GJC1 CX45, GJA7 ENSG00000182963 Gap junction protein, gamma 1, 45kDa 17 44798448-44830816 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA071788 Uncertain Nucleoli
Cell Junctions
Cytosol Renal cancer:3.55e-8 (unfavourable), Urothelial cancer:7.83e-4 (unfavourable) Expressed in all Tissue enhanced endometrium: 43.9;placenta: 50.9;smooth muscle: 48.2 seminal vesicle: 27.0 GPATCH1 ECGP, FLJ10206, FLJ38686, GPATC1 ENSG00000076650 G patch domain containing 1 19 33080880-33130542 Predicted intracellular proteins Evidence at protein level HPA043430, HPA043604 Approved Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Endometrial cancer:8.20e-4 (unfavourable) Expressed in all Mixed parathyroid gland: 8.5 GPR142 PGR2 ENSG00000257008 G protein-coupled receptor 142 17 74367407-74372622 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA031392 Uncertain Uncertain Plasma membrane
Cell Junctions
Cytosol Tissue enhanced Not detected appendix: 0.1 GPR157 FLJ12132 ENSG00000180758 G protein-coupled receptor 157 1 9100305-9129170 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA028697 Uncertain Uncertain Nucleoli
Plasma membrane
Cell Junctions Expressed in all Mixed parathyroid gland: 23.9 HINFP DKFZP434F162, HiNF-P, MIZF, ZNF743 ENSG00000172273 Histone H4 transcription factor 11 119121587-119136044 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059053, HPA061008 Uncertain Supported Nucleus
Cell Junctions
Cytosol Liver cancer:4.44e-8 (unfavourable), Thyroid cancer:5.26e-4 (favourable) Expressed in all Expressed in all testis: 12.0 IGSF11 BT-IgSF, CT119, Igsf13, MGC35227, VSIG3 ENSG00000144847 Immunoglobulin superfamily, member 11 3 118900557-119146068 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046377 Uncertain Approved Nucleus
Cell Junctions
Cytosol Group enriched Tissue enhanced cerebral cortex: 31.1;testis: 64.7 ovary: 20.0 INADL Cipp, PATJ ENSG00000132849 InaD-like (Drosophila) 1 61742477-62178675 Predicted intracellular proteins Evidence at protein level HPA066352, HPA066960, HPA069079 Approved Supported Cell Junctions
Microtubule organizing center
Cytosol Renal cancer:1.47e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 35.2 ITGA2B CD41, CD41B, GP2B, PPP1R93 ENSG00000005961 Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 17 44372180-44389505 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018611, HPA031168, HPA031169, HPA031170, HPA031171 Supported Uncertain Nucleoplasm
Cell Junctions
Cytosol Mixed Tissue enhanced bone marrow: 11.2;epididymis: 28.6 testis: 4.4 ITGB4 CD104 ENSG00000132470 Integrin, beta 4 17 75721328-75757818 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002422, CAB005258, HPA036348, HPA036349 Supported Supported Nucleus
Plasma membrane
Cell Junctions Pancreatic cancer:6.39e-4 (unfavourable), Lung cancer:7.18e-4 (unfavourable) Expressed in all Mixed skin: 84.4 ITGB6 ENSG00000115221 Integrin, beta 6 2 160099666-160271888 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA023626, CAB073536 Approved Uncertain Nucleoplasm
Cell Junctions
Centrosome Pancreatic cancer:5.03e-6 (unfavourable) Mixed Tissue enhanced lung: 66.9 urinary bladder: 31.3 JUP CTNNG, DP3, DPIII, PDGB, PKGB ENSG00000173801 Junction plakoglobin 17 41754604-41786931 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002139, HPA032047 Supported Validated Vesicles
Plasma membrane
Cell Junctions Renal cancer:2.06e-10 (favourable) Expressed in all Group enriched 6 esophagus: 493.6;skin: 787.3 fallopian tube: 112.6 KDF1 C1orf172, FLJ34633, RP11-344H11.3 ENSG00000175707 Keratinocyte differentiation factor 1 1 26949562-26960406 Predicted intracellular proteins Evidence at protein level HPA028639, HPA068312 Uncertain Supported Nucleoplasm
Cell Junctions
Mitotic spindle Renal cancer:3.04e-13 (favourable), Urothelial cancer:4.40e-4 (favourable) Mixed Mixed epididymis: 23.7 KIAA1522 ENSG00000162522 KIAA1522 1 32741885-32774970 Predicted intracellular proteins Evidence at protein level HPA032050, HPA032051, HPA064839 Approved Supported Nucleoplasm
Plasma membrane
Cell Junctions Liver cancer:6.29e-7 (unfavourable), Renal cancer:1.29e-5 (favourable), Pancreatic cancer:8.25e-5 (unfavourable) Expressed in all Mixed skin: 73.0 LRRC34 MGC27085 ENSG00000171757 Leucine rich repeat containing 34 3 169793428-169812986 Predicted intracellular proteins Evidence at protein level HPA035747, HPA058105 Approved Approved Cell Junctions
Microtubules
Cytokinetic bridge Mixed Group enriched 8 fallopian tube: 12.2;testis: 26.8 cerebral cortex,thyroid gland: 2.3 MACF1 ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF ENSG00000127603 Microtubule-actin crosslinking factor 1 1 39081316-39487177 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013713, HPA068064, HPA068103 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Renal cancer:2.77e-5 (favourable) Expressed in all Expressed in all lung: 137.3 MAPK15 ERK7, ERK8 ENSG00000181085 Mitogen-activated protein kinase 15 8 143716259-143722458 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002704 Approved Nucleoplasm
Cell Junctions
Cytosol Mixed Tissue enhanced fallopian tube: 43.3 parathyroid gland: 13.2 METTL9 DREV1 ENSG00000197006 Methyltransferase like 9 16 21597218-21657473 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053588, HPA056347 Uncertain Approved Nucleus
Cell Junctions
Cytosol Liver cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all kidney: 182.7 MICALL1 KIAA1668, MICAL-L1, MIRAB13 ENSG00000100139 MICAL-like 1 22 37905657-37942822 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043480, HPA051956 Uncertain Supported Cell Junctions
Microtubule organizing center
Cytosol Liver cancer:3.08e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 50.6 MLLT4 AF-6, AF6 ENSG00000130396 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 6 167826922-167972023 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868 Approved Validated Nucleoplasm
Plasma membrane
Cell Junctions Breast cancer:7.43e-5 (unfavourable) Expressed in all Expressed in all esophagus: 111.1 MLST8 GbetaL, GBL, Lst8, Pop3 ENSG00000167965 MTOR associated protein, LST8 homolog 16 2204248-2209416 Predicted intracellular proteins Evidence at protein level CAB019935, HPA041841 Approved Approved Nucleoplasm
Golgi apparatus
Cell Junctions Renal cancer:7.60e-4 (favourable) Expressed in all Expressed in all testis: 28.7 MRPL46 C15orf4, LIECG2, P2ECSL ENSG00000259494 Mitochondrial ribosomal protein L46 15 88459476-88467419 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050166 Uncertain Supported Nucleoplasm
Cell Junctions
Mitochondria Renal cancer:2.09e-6 (favourable) Expressed in all Expressed in all adrenal gland: 50.5 NLK ENSG00000087095 Nemo-like kinase 17 28041737-28196381 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018192, HPA056511 Approved Supported Nucleus
Nucleoli
Cell Junctions Expressed in all Expressed in all cerebral cortex: 52.5 NLRX1 CLR11.3, NOD9 ENSG00000160703 NLR family member X1 11 119166568-119184016 Predicted intracellular proteins Evidence at protein level HPA061516 Supported Supported Plasma membrane
Cell Junctions
Mitochondria Renal cancer:2.59e-6 (favourable), Endometrial cancer:2.47e-5 (favourable) Expressed in all Expressed in all esophagus: 37.9 NPNT EGFL6L, POEM ENSG00000168743 Nephronectin 4 105894775-106004027 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003711, HPA050203 Supported Approved Nucleus
Cell Junctions
Cytosol Renal cancer:8.28e-8 (favourable) Expressed in all Tissue enhanced lung: 168.7;thyroid gland: 274.6 prostate: 126.2 NR2C1 TR2, TR2-11 ENSG00000120798 Nuclear receptor subfamily 2, group C, member 1 12 95020229-95073703 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035040, HPA035041, HPA067767 Supported Supported Nucleus
Cell Junctions
Cytosol Renal cancer:1.03e-6 (unfavourable), Liver cancer:5.18e-5 (unfavourable), Urothelial cancer:5.62e-5 (favourable) Expressed in all Mixed testis: 21.8 NUDT9 MGC3037 ENSG00000170502 Nudix (nucleoside diphosphate linked moiety X)-type motif 9 4 87422582-87459454 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036917, HPA044866, HPA078535 Approved Supported Nuclear membrane
Cell Junctions
Mitochondria Renal cancer:8.00e-11 (favourable), Endometrial cancer:7.43e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 84.9 PAK6 PAK5 ENSG00000137843 P21 protein (Cdc42/Rac)-activated kinase 6 15 40238759-40277487 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA031124 Approved Approved Nucleus
Nucleoli fibrillar center
Cell Junctions Not detected Mixed cerebral cortex: 28.7 PAK6 ENSG00000259288 P21 protein (Cdc42/Rac)-activated kinase 6 15 40217428-40276396 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA031124 Uncertain Approved Nucleus
Nucleoli fibrillar center
Cell Junctions Not detected Not detected cerebral cortex: 0.1 PARD6A PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40 ENSG00000102981 Par-6 family cell polarity regulator alpha 16 67660946-67662778 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009733, HPA041551 Approved Supported Cell Junctions
Actin filaments
Cytosol Renal cancer:3.08e-7 (favourable), Breast cancer:5.40e-4 (favourable) Expressed in all Tissue enhanced testis: 20.0 cerebral cortex: 12.1 PCDH1 pc42 ENSG00000156453 Protocadherin 1 5 141853111-141879246 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047720, HPA050538 Approved Approved Nucleus
Nucleoli
Cell Junctions Liver cancer:4.96e-5 (unfavourable), Renal cancer:7.55e-5 (favourable), Pancreatic cancer:3.61e-4 (unfavourable) Expressed in all Mixed cerebral cortex: 40.4 PDGFRA CD140a, GAS9, PDGFR2 ENSG00000134853 Platelet-derived growth factor receptor, alpha polypeptide 4 54229097-54298247 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA004947, CAB018143 Supported Supported Nucleus
Plasma membrane
Cell Junctions Renal cancer:9.79e-6 (unfavourable), Head and neck cancer:9.33e-4 (favourable) Expressed in all Expressed in all ovary: 222.0 PDLIM1 CLIM1, CLP-36, CLP36, hCLIM1 ENSG00000107438 PDZ and LIM domain 1 10 95237572-95291024 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017010, CAB072838, CAB072840 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Endometrial cancer:1.14e-5 (favourable) Expressed in all Expressed in all small intestine: 278.6 PEAR1 FLJ00193, JEDI, MEGF12 ENSG00000187800 Platelet endothelial aggregation receptor 1 1 156893698-156916434 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA035217 Approved Approved Nucleoplasm
Cell Junctions
Centrosome Renal cancer:4.31e-4 (unfavourable) Expressed in all Mixed placenta: 16.8 PGS1 DKFZP762M186 ENSG00000087157 Phosphatidylglycerophosphate synthase 1 17 78378640-78425114 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022526 Approved Approved Vesicles
Cell Junctions
Intermediate filaments Renal cancer:1.16e-5 (unfavourable), Pancreatic cancer:7.33e-5 (favourable), Liver cancer:1.37e-4 (unfavourable), Prostate cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 26.5 PKP3 ENSG00000184363 Plakophilin 3 11 392614-404908 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012993, HPA062937 Supported Validated Nucleoplasm
Cell Junctions
Cytosol Lung cancer:2.89e-5 (unfavourable), Renal cancer:1.08e-4 (unfavourable), Pancreatic cancer:3.93e-4 (unfavourable) Mixed Tissue enhanced esophagus: 98.6;skin: 148.5 duodenum: 32.2 PLEKHA6 KIAA0969, PEPP3 ENSG00000143850 Pleckstrin homology domain containing, family A member 6 1 204218851-204377665 Predicted intracellular proteins Evidence at protein level HPA028152, HPA054311 Approved Supported Vesicles
Cell Junctions
Microtubule organizing center Urothelial cancer:3.57e-4 (favourable) Expressed in all Mixed stomach: 26.7 PLXNA3 6.3, Plxn3, PLXN4, SEX, XAP-6 ENSG00000130827 Plexin A3 X 154458281-154477779 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA058989 Supported Vesicles
Plasma membrane
Cell Junctions Expressed in all Mixed skin: 12.1 PROM2 ENSG00000155066 Prominin 2 2 95274453-95291308 Predicted membrane proteins Evidence at protein level CAB046005, HPA063728 Supported Approved Nucleoplasm
Plasma membrane
Cell Junctions Renal cancer:1.55e-6 (unfavourable), Breast cancer:2.16e-4 (unfavourable), Pancreatic cancer:2.90e-4 (unfavourable) Mixed Tissue enhanced skin: 71.3 esophagus: 44.8 PSEN1 AD3, FAD, PS1, S182 ENSG00000080815 Presenilin 1 14 73136418-73223691 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB006844, HPA030760, HPA067496 Approved Approved Nucleus
Golgi apparatus
Cell Junctions Renal cancer:1.52e-8 (favourable), Liver cancer:1.99e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 66.1 PTPRB PTPB ENSG00000127329 Protein tyrosine phosphatase, receptor type, B 12 70515866-70637440 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004782, HPA067868 Uncertain Approved Vesicles
Plasma membrane
Cell Junctions Renal cancer:1.02e-4 (favourable), Liver cancer:6.05e-4 (favourable) Expressed in all Mixed lung: 54.1 PTPRK R-PTP-kappa ENSG00000152894 Protein tyrosine phosphatase, receptor type, K 6 127968779-128520674 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054056, HPA054822 Uncertain Supported Vesicles
Plasma membrane
Cell Junctions Renal cancer:9.33e-5 (favourable), Pancreatic cancer:1.99e-4 (unfavourable) Expressed in all Mixed gallbladder: 27.9 PTPRR EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ ENSG00000153233 Protein tyrosine phosphatase, receptor type, R 12 70638073-70920843 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB011461, HPA011851, HPA071067 Uncertain Supported Plasma membrane
Cell Junctions
Cytosol Urothelial cancer:1.40e-5 (favourable) Mixed Tissue enhanced cerebral cortex: 20.9 endometrium: 8.9 PVALB D22S749 ENSG00000100362 Parvalbumin 22 36800684-36819479 Predicted intracellular proteins Evidence at protein level CAB002515, HPA048536 Supported Approved Nucleoplasm
Nucleoli
Cell Junctions Group enriched Tissue enriched 12 parathyroid gland: 536.6 kidney: 43.1 RASAL1 RASAL ENSG00000111344 RAS protein activator like 1 (GAP1 like) 12 113098819-113136239 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA041650 Uncertain Approved Plasma membrane
Cell Junctions
Cytosol Endometrial cancer:3.26e-5 (unfavourable) Mixed Tissue enriched 6 parathyroid gland: 116.7 cerebral cortex: 19.5 RASSF4 AD037, MGC44914 ENSG00000107551 Ras association (RalGDS/AF-6) domain family member 4 10 44959407-44995891 Predicted intracellular proteins Evidence at protein level HPA038834 Approved Approved Nucleus
Nucleoli
Cell Junctions Expressed in all Expressed in all cerebral cortex: 71.6 RRP7A CGI-96 ENSG00000189306 Ribosomal RNA processing 7 homolog A 22 42509968-42519802 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001586, HPA046768 Approved Approved Nucleus
Nucleoli
Cell Junctions Liver cancer:1.21e-5 (unfavourable) Expressed in all Expressed in all epididymis: 49.0 S100A14 BCMP84, S100A15 ENSG00000189334 S100 calcium binding protein A14 1 153614255-153616986 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027613 Supported Supported Nuclear bodies
Cell Junctions
Cytosol Mixed Tissue enhanced esophagus: 2214.5 skin: 592.3 S100A9 60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14 ENSG00000163220 S100 calcium binding protein A9 1 153357854-153361027 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004193, CAB009441 Supported Supported Nucleoplasm
Cell Junctions
Cytosol Liver cancer:1.13e-6 (unfavourable), Renal cancer:8.10e-4 (unfavourable) Expressed in all Group enriched 6 bone marrow: 21012.0;esophagus: 24343.4 tonsil: 4079.1 SCAMP1 SCAMP37 ENSG00000085365 Secretory carrier membrane protein 1 5 78360583-78479071 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044753 Approved Nucleoplasm
Vesicles
Cell Junctions Renal cancer:1.92e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 69.4 SHROOM2 APXL ENSG00000146950 Shroom family member 2 X 9786456-9949443 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051646 Approved Approved Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.35e-7 (favourable) Expressed in all Mixed cerebral cortex: 11.8 SLC38A6 NAT-1 ENSG00000139974 Solute carrier family 38, member 6 14 60981114-61083733 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018508 Approved Approved Plasma membrane
Cell Junctions
Microtubules Liver cancer:9.47e-6 (unfavourable), Renal cancer:1.37e-5 (unfavourable) Expressed in all Mixed parathyroid gland: 24.3 SLC5A7 CHT1, hCHT ENSG00000115665 Solute carrier family 5 (sodium/choline cotransporter), member 7 2 107986523-108013994 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046105 Approved Nuclear bodies
Cell Junctions
Intermediate filaments Tissue enhanced Mixed thyroid gland: 2.0 SLX4 BTBD12, FANCP, KIAA1784, KIAA1987 ENSG00000188827 SLX4 structure-specific endonuclease subunit 16 3581181-3611598 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049421, HPA066238 Approved Supported Nucleoplasm
Cell Junctions
Cytosol Expressed in all Tissue enhanced testis: 12.8 lymph node: 4.9 SMPD2 ISC1, nSMase ENSG00000135587 Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 6 109440763-109443919 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018110, HPA018125 Uncertain Approved Vesicles
Plasma membrane
Cell Junctions Liver cancer:1.17e-4 (unfavourable), Urothelial cancer:1.70e-4 (favourable), Pancreatic cancer:1.00e-3 (favourable) Expressed in all Mixed testis: 55.6 SPN CD43, GPL115, LSN ENSG00000197471 Sialophorin 16 29662979-29670876 CD markers, Predicted membrane proteins Evidence at protein level CAB002666, HPA055244 Supported Uncertain Golgi apparatus
Plasma membrane
Cell Junctions Endometrial cancer:3.08e-5 (favourable), Breast cancer:1.40e-4 (favourable), Melanoma:1.88e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 38.7;lung: 33.4 lymph node: 25.8 SYNPO2L FLJ12921 ENSG00000166317 Synaptopodin 2-like 10 73644881-73663803 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055192, HPA057142 Supported Approved Nuclear speckles
Cell Junctions
Cytosol Group enriched Group enriched 11 heart muscle: 158.4;skeletal muscle: 96.0 esophagus: 11.2 TCAF2 FAM115C, FAM139A, FLJ40722 ENSG00000170379 TRPM8 channel-associated factor 2 7 143620950-143730409 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038756, HPA038758 Uncertain Supported Endoplasmic reticulum
Plasma membrane
Cell Junctions Renal cancer:4.17e-6 (unfavourable), Glioma:6.78e-5 (unfavourable) Mixed Mixed placenta: 8.4 TJP2 DFNA51, X104, ZO-2, ZO2 ENSG00000119139 Tight junction protein 2 9 69121264-69255208 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001813, CAB009228 Supported Validated Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.78e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 136.2 TM4SF5 ENSG00000142484 Transmembrane 4 L six family member 5 17 4771884-4783213 Predicted membrane proteins Evidence at protein level HPA055674 Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Tissue enriched Group enriched 5 duodenum: 181.8;small intestine: 172.8 liver: 33.2 TMEM183A C1orf37 ENSG00000163444 Transmembrane protein 183A 1 203007386-203024848 Predicted membrane proteins Evidence at protein level HPA072607 Approved Nucleus
Plasma membrane
Cell Junctions Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all testis: 58.5 TPD52L1 D53, hD53 ENSG00000111907 Tumor protein D52-like 1 6 125119049-125264407 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027915, HPA027916 Approved Approved Plasma membrane
Cell Junctions
Cytosol Renal cancer:3.26e-4 (favourable), Thyroid cancer:3.97e-4 (favourable), Urothelial cancer:5.34e-4 (unfavourable) Expressed in all Tissue enhanced adrenal gland: 321.3 salivary gland: 126.8 TRIM38 RNF15, RORET ENSG00000112343 Tripartite motif containing 38 6 25962802-25991226 Predicted intracellular proteins Evidence at protein level HPA031685 Approved Approved Plasma membrane
Cell Junctions
Centrosome Urothelial cancer:4.94e-9 (favourable), Thyroid cancer:8.20e-5 (favourable), Ovarian cancer:8.95e-5 (favourable) Expressed in all Mixed spleen: 20.1 UBALD1 FAM100A ENSG00000153443 UBA-like domain containing 1 16 4608883-4615027 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA066771 Approved Approved Nucleus
Cell Junctions
Cytosol Expressed in all Expressed in all cerebral cortex: 23.9 UBXN10 FLJ25429, UBXD3 ENSG00000162543 UBX domain protein 10 1 20186085-20196048 Predicted intracellular proteins Evidence at protein level HPA028555, HPA028564 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cell Junctions Glioma:1.64e-4 (unfavourable), Endometrial cancer:2.02e-4 (favourable) Mixed Tissue enhanced fallopian tube: 78.2 testis: 25.4 VASP ENSG00000125753 Vasodilator-stimulated phosphoprotein 19 45506579-45526983 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004612, HPA005724 Supported Supported Plasma membrane
Cell Junctions
Focal adhesion sites Renal cancer:5.91e-7 (unfavourable), Liver cancer:3.49e-5 (unfavourable) Expressed in all Expressed in all appendix: 93.1 VTCN1 B7-H4, B7H4, B7S1, B7X, FLJ22418 ENSG00000134258 V-set domain containing T cell activation inhibitor 1 1 117143587-117210960 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054200 Approved Approved Plasma membrane
Cell Junctions
Focal adhesion sites Group enriched Tissue enhanced breast: 127.6;fallopian tube: 50.8 cervix, uterine: 21.9 ZNF236 ENSG00000130856 Zinc finger protein 236 18 76822607-76970727 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008600 Uncertain Approved Nucleoplasm
Cell Junctions
Cytosol Expressed in all Mixed testis: 13.2 ZNF688 ENSG00000229809 Zinc finger protein 688 16 30569346-30572734 Predicted intracellular proteins Evidence at transcript level HPA048922 Uncertain Approved Nucleoplasm
Plasma membrane
Cell Junctions Endometrial cancer:4.58e-5 (favourable), Lung cancer:3.24e-4 (favourable), Breast cancer:5.90e-4 (favourable), Pancreatic cancer:6.61e-4 (favourable), Cervical cancer:7.74e-4 (favourable) Expressed in all Expressed in all testis: 23.9