Search: subcell_location:Mitochondria AND protein_class:Enzymes;Oxidoreductases - The Human Protein Atlas

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74 GENES FOUND

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Gene

Gene description	x

Protein class	x

Tissue

Cell

Pathology

Subcellular location	x

RNA tissue category	x

AASS

Aminoadipate-semialdehyde synthase

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Vesicles
Mitochondria

Acyl-CoA dehydrogenase, C-4 to C-12 straight chain

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Expressed in all

Acyl-CoA dehydrogenase, C-2 to C-3 short chain

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Nucleoplasm
Mitochondria

Expressed in all

Acyl-CoA dehydrogenase, short/branched chain

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Expressed in all

Acyl-CoA dehydrogenase, very long chain

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Nucleus
Nucleoli
Mitochondria

Expressed in all

Acyl-CoA oxidase 2, branched chain

Enzymes
Predicted intracellular proteins

Vesicles
Mitochondria

Tissue enhanced

Aldehyde dehydrogenase 18 family, member A1

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Expressed in all

Aldehyde dehydrogenase 1 family, member B1

Enzymes
Predicted intracellular proteins

Nucleoplasm
Vesicles
Mitochondria

Expressed in all

Aldehyde dehydrogenase 1 family, member L2

Enzymes
Predicted intracellular proteins

Aldehyde dehydrogenase 5 family, member A1

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Expressed in all

Aldehyde dehydrogenase 6 family, member A1

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins

Expressed in all

Aldehyde dehydrogenase 7 family, member A1

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Mitochondria
Cytosol

Expressed in all

BDH1

3-hydroxybutyrate dehydrogenase, type 1

Candidate cardiovascular disease genes
Enzymes
Predicted intracellular proteins

Tissue enriched

CPOX

Coproporphyrinogen oxidase

Disease related genes
Enzymes
Potential drug targets
Predicted membrane proteins

Expressed in all

Cytochrome b5 reductase 1

Enzymes
Predicted intracellular proteins

Nucleoli
Mitochondria
Cytosol

Expressed in all

Cytochrome P450, family 1, subfamily B, polypeptide 1

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins

Cytochrome P450, family 24, subfamily A, polypeptide 1

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Nucleoplasm
Plasma membrane
Mitochondria

Tissue enhanced

Cytochrome P450, family 27, subfamily A, polypeptide 1

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Tissue enhanced

2,4-dienoyl CoA reductase 1, mitochondrial

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Mitochondria
Cytosol

Expressed in all

Delta(4)-desaturase, sphingolipid 1

Enzymes
Predicted membrane proteins

Expressed in all

DHFR

Dihydrofolate reductase

Cancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins

Dihydrofolate reductase-like 1

Enzymes
Predicted intracellular proteins

Dihydroorotate dehydrogenase (quinone)

Disease related genes
Enzymes
FDA approved drug targets
Predicted intracellular proteins
Predicted membrane proteins

Nucleoplasm
Mitochondria

Dehydrogenase/reductase (SDR family) member 3

Enzymes
Predicted intracellular proteins
Predicted membrane proteins

Nucleoli
Mitochondria

Expressed in all

Dehydrogenase E1 and transketolase domain containing 1

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Expressed in all

DLD

Dihydrolipoamide dehydrogenase

Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Expressed in all

Dimethylglycine dehydrogenase

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Ethylmalonic encephalopathy 1

Cancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Expressed in all

FDXR

Ferredoxin reductase

Enzymes
Predicted intracellular proteins

Tissue enriched

FXN

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted secreted proteins
Transporters

Mitochondria
Cytosol

Expressed in all

GCDH

Glutaryl-CoA dehydrogenase

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Expressed in all

GFER

Growth factor, augmenter of liver regeneration

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Mitochondria
Cytosol

Expressed in all

GLDC

Glycine dehydrogenase (decarboxylating)

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Nucleus
Mitochondria

Tissue enhanced

Glutamate dehydrogenase 1

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted secreted proteins

Expressed in all

Glutamate dehydrogenase 2

Enzymes
Predicted intracellular proteins

Tissue enriched

GPX4

Glutathione peroxidase 4

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted secreted proteins

Nucleoplasm
Mitochondria

Expressed in all

HADH

Hydroxyacyl-CoA dehydrogenase

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Expressed in all

Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit

Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Expressed in all

IDH2

Isocitrate dehydrogenase 2 (NADP+), mitochondrial

Cancer-related genes
Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Expressed in all

Isocitrate dehydrogenase 3 (NAD+) alpha

Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins

Expressed in all

Isocitrate dehydrogenase 3 (NAD+) beta

Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins

Expressed in all

Isocitrate dehydrogenase 3 (NAD+) gamma

Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins

Expressed in all

IVD

Isovaleryl-CoA dehydrogenase

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Nucleoplasm
Mitochondria

Expressed in all

L-2-hydroxyglutarate dehydrogenase

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

MAOA

Monoamine oxidase A

Disease related genes
Enzymes
FDA approved drug targets
Predicted membrane proteins

MAOB

Monoamine oxidase B

Enzymes
FDA approved drug targets
Predicted membrane proteins

Nucleoli
Mitochondria

MDH2

Malate dehydrogenase 2, NAD (mitochondrial)

Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins

Expressed in all

ME2

Malic enzyme 2, NAD(+)-dependent, mitochondrial

Enzymes
Plasma proteins
Predicted intracellular proteins

Expressed in all

MECR

Mitochondrial trans-2-enoyl-CoA reductase

Enzymes
Predicted intracellular proteins

Expressed in all

Mitochondrially encoded cytochrome c oxidase I

Disease related genes
Enzymes
Potential drug targets
Predicted membrane proteins
Transporters

Expressed in all

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.