Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific A2M CPAMD5, FWP007, S863-7 ENSG00000175899 Alpha-2-macroglobulin 12 9067664-9116229 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002265, CAB017621 Supported Expressed in all Expressed in all lung: 1921.7 AAAS ENSG00000094914 Achalasia, adrenocortical insufficiency, alacrimia 12 53307456-53324864 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA040086 Approved Approved Nuclear membrane
Centrosome
Cytosol Renal cancer:2.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.9 AACS ACSF1, FLJ12389, SUR-5 ENSG00000081760 Acetoacetyl-CoA synthetase 12 125065379-125143333 Enzymes, Predicted membrane proteins Evidence at protein level HPA058815 Approved Approved Vesicles Expressed in all Expressed in all breast: 54.1 AAED1 C9orf21 ENSG00000158122 AhpC/TSA antioxidant enzyme domain containing 1 9 96639577-96655303 Predicted intracellular proteins Evidence at protein level HPA021294 Approved Renal cancer:3.26e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 15.9 AAGAB FLJ11506, p34 ENSG00000103591 Alpha- and gamma-adaptin binding protein 15 67201033-67255195 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039371, HPA040174 Supported Supported Nuclear speckles
Cytosol Renal cancer:1.36e-4 (favourable), Thyroid cancer:9.48e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 55.4 AAMDC C11orf67, CK067, FLJ21035, PTD015 ENSG00000087884 Adipogenesis associated, Mth938 domain containing 11 77821109-77918432 Predicted intracellular proteins Evidence at protein level HPA037918, HPA037919 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all skeletal muscle: 231.8 AAMP ENSG00000127837 Angio-associated, migratory cell protein 2 218264123-218270257 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017717, HPA031868 Approved Supported Microtubules
Cytosol Liver cancer:4.94e-7 (unfavourable), Endometrial cancer:1.62e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 114.8 AAR2 bA234K24.2, C20orf4 ENSG00000131043 AAR2 splicing factor homolog 20 36236459-36270918 Predicted intracellular proteins Evidence at protein level CAB034220, HPA048645 Uncertain Approved Cytosol Liver cancer:1.83e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 41.5 AARS CMT2N ENSG00000090861 Alanyl-tRNA synthetase 16 70252295-70289543 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB034261, HPA040870, HPA044223 Supported Validated Cytosol Expressed in all Expressed in all parathyroid gland: 174.6 AARSD1 MGC2744 ENSG00000266967 Alanyl-tRNA synthetase domain containing 1 17 42950526-42964498 Predicted intracellular proteins Evidence at protein level HPA021408, HPA022869, HPA023714 Supported Approved Nuclear membrane
Cytosol Renal cancer:1.67e-6 (unfavourable) Expressed in all Expressed in all testis: 99.0 AASDHPPT AASD-PPT, CGI-80, LYS5 ENSG00000149313 Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 11 106075501-106098710 Predicted intracellular proteins Evidence at protein level HPA020253, HPA026687 Approved Approved Mitochondria Renal cancer:4.27e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 82.1 AATF BFR2, CHE-1, CHE1, DED ENSG00000275700 Apoptosis antagonizing transcription factor 17 36948875-37056871 Predicted intracellular proteins Evidence at protein level HPA004940 Uncertain Renal cancer:4.14e-5 (unfavourable), Liver cancer:6.62e-5 (unfavourable) Expressed in all Expressed in all lymph node: 20.1 ABCA5 EST90625 ENSG00000154265 ATP-binding cassette, sub-family A (ABC1), member 5 17 69244311-69327244 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA022032 Approved Pancreatic cancer:9.97e-5 (favourable) Expressed in all Expressed in all skin: 28.0 ABCB10 EST20237, M-ABC2, MTABC2 ENSG00000135776 ATP-binding cassette, sub-family B (MDR/TAP), member 10 1 229516582-229558695 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB044063, CAB044065, HPA055175 Uncertain Expressed in all Expressed in all bone marrow: 36.6 ABCB6 EST45597, MTABC3, umat ENSG00000115657 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2 219209768-219218990 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046723, HPA058011 Approved Validated Nucleoplasm
Golgi apparatus
Plasma membrane
Mitochondria
Cytosol Renal cancer:1.52e-7 (unfavourable), Liver cancer:9.45e-7 (unfavourable) Expressed in all Expressed in all testis: 32.5 ABCB7 ABC7, ASAT, Atm1p, EST140535 ENSG00000131269 ATP-binding cassette, sub-family B (MDR/TAP), member 7 X 75053172-75156732 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA034982 Approved Supported Mitochondria Renal cancer:5.31e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 21.3 ABCB8 EST328128, M-ABC1, MABC1 ENSG00000197150 ATP-binding cassette, sub-family B (MDR/TAP), member 8 7 151028422-151047782 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA045187 Approved Supported Nucleus
Mitochondria Pancreatic cancer:3.34e-4 (favourable), Renal cancer:5.88e-4 (favourable), Head and neck cancer:5.91e-4 (favourable) Expressed in all Expressed in all thyroid gland: 17.0 ABCC10 EST182763, MRP7, SIMRP7 ENSG00000124574 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 6 43427366-43450430 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041607, HPA045464 Approved Renal cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 12.4 ABCC5 EST277145, MOAT-C, MRP5, SMRP ENSG00000114770 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3 183919934-184018015 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA044067, HPA052295 Uncertain Supported Nucleus
Plasma membrane
Cell Junctions Liver cancer:6.78e-8 (unfavourable), Prostate cancer:3.40e-4 (unfavourable) Expressed in all Expressed in all stomach: 72.0 ABCD1 adrenoleukodystrophy, ALD, ALDP, AMN ENSG00000101986 ATP-binding cassette, sub-family D (ALD), member 1 X 153724868-153744762 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:5.50e-4 (unfavourable) Expressed in all Expressed in all small intestine: 19.7 ABCD3 PMP70, PXMP1, ZWS2 ENSG00000117528 ATP-binding cassette, sub-family D (ALD), member 3 1 94418455-94518666 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA032026, HPA032027, CAB032516, CAB075749 Supported Validated Peroxisomes Colorectal cancer:1.16e-5 (favourable), Renal cancer:4.84e-5 (favourable) Expressed in all Expressed in all liver: 66.4 ABCD4 EST352188, P70R, PMP69, PXMP1L ENSG00000119688 ATP-binding cassette, sub-family D (ALD), member 4 14 74285423-74303056 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA003396 Approved Expressed in all Expressed in all fallopian tube: 13.6 ABCE1 OABP, RLI, RNASEL1, RNASELI, RNS4I ENSG00000164163 ATP-binding cassette, sub-family E (OABP), member 1 4 145097932-145129179 Predicted intracellular proteins Evidence at protein level CAB012476, HPA036846 Approved Validated Cytosol Pancreatic cancer:1.88e-4 (unfavourable), Liver cancer:6.29e-4 (unfavourable), Colorectal cancer:8.69e-4 (favourable) Expressed in all Expressed in all testis: 45.9 ABCF2 ABC28, EST133090, HUSSY-18, M-ABC1 ENSG00000033050 ATP-binding cassette, sub-family F (GCN20), member 2 7 151207837-151227230 Predicted intracellular proteins Evidence at protein level HPA020091, CAB020682, HPA021815, HPA030388 Supported Supported Cytosol Liver cancer:9.52e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 51.2 ABCF3 EST201864 ENSG00000161204 ATP-binding cassette, sub-family F (GCN20), member 3 3 184186023-184194012 Predicted intracellular proteins Evidence at protein level HPA036332 Approved Approved Nucleoli
Cytosol Liver cancer:4.16e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.8 ABCG1 ABC8 ENSG00000160179 ATP-binding cassette, sub-family G (WHITE), member 1 21 42199689-42297244 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA031470, HPA031471 Approved Supported Golgi apparatus
Vesicles Renal cancer:7.16e-6 (favourable) Expressed in all Expressed in all spleen: 43.7 ABHD10 FLJ11342 ENSG00000144827 Abhydrolase domain containing 10 3 111979010-111993363 Enzymes, Predicted secreted proteins Evidence at protein level HPA036991, HPA036992, HPA066081 Supported Approved Mitochondria Renal cancer:4.72e-9 (favourable), Cervical cancer:7.57e-4 (favourable) Expressed in all Expressed in all epididymis: 61.2 ABHD11 PP1226, WBSCR21 ENSG00000106077 Abhydrolase domain containing 11 7 73736094-73738867 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024042, HPA049641 Approved Supported Mitochondria Renal cancer:3.66e-7 (favourable) Expressed in all Expressed in all thyroid gland: 28.6 ABHD12 ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106 ENSG00000100997 Abhydrolase domain containing 12 20 25294743-25390983 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026866 Uncertain Cervical cancer:1.30e-5 (favourable), Breast cancer:3.81e-5 (unfavourable), Liver cancer:7.18e-4 (unfavourable) Expressed in all Expressed in all epididymis: 135.4 ABHD14A DKFZP564O243, DORZ1 ENSG00000248487 Abhydrolase domain containing 14A 3 51971426-51981199 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA038153, HPA038154, HPA056913 Approved Supported Vesicles Lung cancer:4.72e-4 (favourable) Expressed in all Expressed in all thyroid gland: 50.8 ABHD14B CIB, MGC15429 ENSG00000114779 Abhydrolase domain containing 14B 3 51968510-51983409 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036444, HPA036642 Supported Supported Nucleus
Nucleoli
Cytosol Renal cancer:2.93e-5 (favourable), Endometrial cancer:5.42e-5 (favourable), Cervical cancer:6.92e-5 (favourable) Expressed in all Expressed in all thyroid gland: 90.5 ABHD17B C9orf77, CGI-67, FAM108B1 ENSG00000107362 Abhydrolase domain containing 17B 9 71862452-71910931 Predicted intracellular proteins Evidence at protein level HPA047862 Uncertain Renal cancer:2.59e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 35.5 ABHD18 C4orf29, FLJ21106 ENSG00000164074 Abhydrolase domain containing 18 4 127965306-128039711 Predicted intracellular proteins Evidence at protein level HPA050168, HPA051676 Approved Approved Nuclear membrane Colorectal cancer:5.35e-4 (favourable), Urothelial cancer:9.13e-4 (favourable) Expressed in all Expressed in all heart muscle: 9.5 ABHD2 LABH2 ENSG00000140526 Abhydrolase domain containing 2 15 89087459-89202360 Predicted membrane proteins Evidence at protein level HPA005999 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.18e-7 (favourable) Expressed in all Expressed in all testis: 99.6 ABHD3 LABH3 ENSG00000158201 Abhydrolase domain containing 3 18 21650897-21704805 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010729 Approved Approved Nucleus
Vesicles
Plasma membrane Melanoma:8.52e-4 (unfavourable) Expressed in all Expressed in all rectum: 72.4 ABHD4 FLJ12816 ENSG00000100439 Abhydrolase domain containing 4 14 22598237-22613215 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000600 Uncertain Approved Nucleus Expressed in all Expressed in all testis: 62.6 ABHD5 CGI-58, NCIE2 ENSG00000011198 Abhydrolase domain containing 5 3 43690113-43734371 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB020685, HPA035851, HPA035852 Approved Approved Vesicles Renal cancer:9.17e-5 (favourable), Colorectal cancer:8.89e-4 (favourable) Expressed in all Expressed in all adipose tissue: 50.3 ABI1 ABI-1, E3B1, SSH3BP1 ENSG00000136754 Abl-interactor 1 10 26746593-26861087 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB008375, HPA029973, HPA068407 Approved Supported Plasma membrane
Cell Junctions Expressed in all Expressed in all cerebral cortex: 87.6 ABI2 ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2 ENSG00000138443 Abl-interactor 2 2 203328219-203447723 Predicted intracellular proteins Evidence at protein level HPA062433, HPA070567 Supported Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 99.1 ABL1 ABL, c-ABL, JTK7, p150 ENSG00000097007 ABL proto-oncogene 1, non-receptor tyrosine kinase 9 130713946-130887675 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002686, HPA027251, HPA027280, HPA028409 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 82.2 ABLIM1 ABLIM, LIMAB1, limatin ENSG00000099204 Actin binding LIM protein 1 10 114431113-114685003 Predicted intracellular proteins Evidence at protein level HPA038951, HPA038952 Approved Supported Cytosol Renal cancer:2.72e-5 (favourable) Expressed in all Expressed in all ovary: 283.7 ABT1 ENSG00000146109 Activator of basal transcription 1 6 26596952-26600744 Predicted intracellular proteins Evidence at protein level Ovarian cancer:1.89e-4 (favourable), Urothelial cancer:3.80e-4 (favourable) Expressed in all Expressed in all lymph node: 18.1 ABTB1 BPOZ, Btb3, BTBD21, EF1ABP ENSG00000114626 Ankyrin repeat and BTB (POZ) domain containing 1 3 127672935-127680920 Predicted intracellular proteins Evidence at protein level HPA035022, HPA035023 Uncertain Supported Nucleoli
Cytosol Renal cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 51.1 AC004813.1 ENSG00000279777 12 119918001-119918375 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Not detected Expressed in all testis: 38.8 AC006449.2 ENSG00000279119 17 38727833-38728198 Predicted intracellular proteins Evidence at transcript level HPA023912, HPA074896 Uncertain Approved Vesicles Not detected Expressed in all epididymis: 41.4 AC007326.1 ENSG00000279560 22 18945123-18946971 Predicted intracellular proteins Evidence at transcript level Tissue enriched Expressed in all epididymis: 108.5 AC008810.1 ENSG00000279126 5 40801222-40801596 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Not detected Expressed in all skin: 37.7 AC008914.1 ENSG00000279768 5 55928640-55928741 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all ovary: 78.7 AC009060.2 ENSG00000280006 16 70205400-70205780 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Mixed Expressed in all testis: 85.3 AC013461.1 ENSG00000091436 Mitogen-activated protein kinase kinase kinase MLT 2 173075435-173268010 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017205 Approved Supported Cytosol Renal cancer:3.41e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 132.2 AC026248.1 ENSG00000280151 8 128118011-128118385 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Not detected Expressed in all epididymis: 22.2 AC073333.1 ENSG00000280130 7 16789242-16789622 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Not detected Expressed in all epididymis: 37.9 AC090498.1 ENSG00000279483 7 137513832-137514238 Predicted intracellular proteins Evidence at transcript level HPA053169 Uncertain Renal cancer:8.38e-4 (unfavourable), Liver cancer:9.06e-4 (unfavourable) Expressed in all Expressed in all ovary: 12.8 AC109486.1 ENSG00000280447 5 60430738-60431112 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Tissue enhanced Expressed in all appendix: 33.8 AC138969.4 ENSG00000183889 16 16317444-16350590 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Uncertain Nucleoplasm Not detected Expressed in all skin: 115.8 AC240274.1 ENSG00000271254 Unmapped 4612-29626 Predicted intracellular proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Uncertain Approved Vesicles Expressed in all testis: 73.6 ACAA1 ENSG00000060971 Acetyl-CoA acyltransferase 1 3 38103129-38137242 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006764, HPA007244 Supported Validated Peroxisomes Renal cancer:6.99e-9 (favourable), Head and neck cancer:1.23e-4 (favourable), Breast cancer:3.00e-4 (favourable), Endometrial cancer:7.53e-4 (favourable) Expressed in all Expressed in all liver: 327.6 ACAA2 DSAEC ENSG00000167315 Acetyl-CoA acyltransferase 2 18 49782167-49813960 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042303 Supported Supported Mitochondria Renal cancer:1.36e-10 (favourable), Endometrial cancer:8.53e-4 (unfavourable) Expressed in all Expressed in all liver: 508.4 ACAD10 MGC5601 ENSG00000111271 Acyl-CoA dehydrogenase family, member 10 12 111686056-111757107 Predicted intracellular proteins Evidence at protein level HPA067222 Uncertain Renal cancer:3.71e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 33.5 ACAD11 FLJ12592 ENSG00000240303 Acyl-CoA dehydrogenase family, member 11 3 132558138-132660723 Predicted intracellular proteins Evidence at protein level HPA048317 Supported Tissue enhanced Expressed in all kidney: 36.4 ACAD8 ENSG00000151498 Acyl-CoA dehydrogenase family, member 8 11 134253495-134265855 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040689, HPA043903 Supported Renal cancer:6.42e-10 (favourable), Lung cancer:2.38e-4 (favourable), Head and neck cancer:6.19e-4 (favourable), Colorectal cancer:7.62e-4 (favourable) Expressed in all Expressed in all thyroid gland: 43.1 ACAD9 MGC14452, NPD002 ENSG00000177646 Acyl-CoA dehydrogenase family, member 9 3 128879596-128916067 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037716, HPA046720 Supported Validated Mitochondria Renal cancer:4.32e-8 (favourable), Liver cancer:3.67e-6 (unfavourable), Endometrial cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all skin: 52.8 ACADM ACAD1, MCAD, MCADH ENSG00000117054 Acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1 75724347-75787575 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006198, HPA026542 Supported Validated Mitochondria Renal cancer:3.83e-8 (favourable), Colorectal cancer:7.30e-4 (favourable) Expressed in all Expressed in all kidney: 325.2 ACADS ACAD3, SCAD ENSG00000122971 Acyl-CoA dehydrogenase, C-2 to C-3 short chain 12 120725735-120740008 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004799, CAB019284, HPA022271 Supported Supported Nucleoplasm
Mitochondria Renal cancer:3.33e-6 (favourable), Urothelial cancer:6.34e-5 (favourable), Liver cancer:2.43e-4 (favourable), Endometrial cancer:5.05e-4 (favourable), Glioma:9.94e-4 (unfavourable) Expressed in all Expressed in all duodenum: 83.5 ACADSB ACAD7, SBCAD ENSG00000196177 Acyl-CoA dehydrogenase, short/branched chain 10 123008979-123058311 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041458 Supported Supported Mitochondria Renal cancer:6.37e-12 (favourable), Pancreatic cancer:3.40e-4 (favourable) Expressed in all Expressed in all liver: 186.7 ACADVL ACAD6, LCACD, VLCAD ENSG00000072778 Acyl-CoA dehydrogenase, very long chain 17 7217125-7225273 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019006, HPA020595 Supported Supported Nucleus
Nucleoli
Mitochondria Pancreatic cancer:6.87e-4 (favourable) Expressed in all Expressed in all adrenal gland: 455.8 ACAP2 CENTB2, CNT-B2, KIAA0041 ENSG00000114331 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 3 195274736-195443078 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034807, HPA034808 Supported Approved Endosomes Expressed in all Expressed in all thyroid gland: 34.1 ACAP3 CENTB5, KIAA1716 ENSG00000131584 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 1 1292376-1309609 Predicted intracellular proteins Evidence at protein level HPA049317, HPA058381 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all cerebral cortex: 26.6 ACAT1 ACAT, THIL ENSG00000075239 Acetyl-CoA acetyltransferase 1 11 108121516-108147776 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004428, HPA007569 Supported Validated Mitochondria Renal cancer:0.00e+0 (favourable), Liver cancer:1.43e-5 (favourable) Expressed in all Expressed in all kidney: 530.1 ACBD3 GCP60, GOCAP1, GOLPH1, PAP7 ENSG00000182827 Acyl-CoA binding domain containing 3 1 226144679-226186730 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015594 Uncertain Supported Golgi apparatus Expressed in all Expressed in all thyroid gland: 48.3 ACBD4 FLJ13322 ENSG00000181513 Acyl-CoA binding domain containing 4 17 45132600-45144181 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051772 Approved Approved Nucleus
Vesicles Pancreatic cancer:4.64e-4 (favourable), Liver cancer:4.76e-4 (favourable), Urothelial cancer:6.53e-4 (favourable) Expressed in all Expressed in all duodenum: 31.2 ACBD5 DKFZp434A2417, KIAA1996 ENSG00000107897 Acyl-CoA binding domain containing 5 10 27195214-27242130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011861, HPA012145 Supported Validated Peroxisomes Renal cancer:4.68e-5 (favourable), Breast cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 57.3 ACBD6 MGC2404 ENSG00000230124 Acyl-CoA binding domain containing 6 1 180269653-180502954 Predicted intracellular proteins Evidence at protein level HPA028179, HPA028457 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.02e-7 (unfavourable) Expressed in all Expressed in all testis: 42.0 ACIN1 ACINUS, fSAP152, KIAA0670 ENSG00000100813 Apoptotic chromatin condensation inducer 1 14 23058564-23095614 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA000657 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:4.88e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 76.7 ACKR3 CMKOR1, CXCR7, GPR159, RDC1 ENSG00000144476 Atypical chemokine receptor 3 2 236567787-236582358 Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA032003, HPA049718 Approved Supported Vesicles
Plasma membrane Renal cancer:1.76e-6 (unfavourable), Stomach cancer:2.01e-4 (unfavourable), Urothelial cancer:2.93e-4 (unfavourable), Cervical cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all placenta: 175.2 ACLY ACL, ATPCL, CLATP ENSG00000131473 ATP citrate lyase 17 41866908-41930542 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007783, HPA022434, HPA022953, HPA022959, HPA028758 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Cervical cancer:1.79e-4 (unfavourable), Liver cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all prostate: 95.8 ACO1 IREB1, IREBP, IRP1 ENSG00000122729 Aconitase 1, soluble 9 32384603-32454769 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019371, HPA024157 Supported Supported Mitochondria
Cytosol Renal cancer:5.73e-5 (favourable) Expressed in all Expressed in all adipose tissue: 104.8 ACO2 ACONM ENSG00000100412 Aconitase 2, mitochondrial 22 41469125-41528989 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001097 Supported Supported Mitochondria Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all heart muscle: 306.9 ACOT13 HT012, THEM2 ENSG00000112304 Acyl-CoA thioesterase 13 6 24667035-24705065 Predicted intracellular proteins Evidence at protein level HPA019881 Approved Approved Cell Junctions Ovarian cancer:2.53e-6 (favourable) Expressed in all Expressed in all kidney: 20.9 ACOT2 Mte1, ZAP128 ENSG00000119673 Acyl-CoA thioesterase 2 14 73567620-73575658 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043705 Approved Approved Mitochondria Renal cancer:2.28e-6 (favourable) Expressed in all Expressed in all adipose tissue: 95.7 ACOT8 hACTE-III, hTE, NAP1, PTE-2, PTE1 ENSG00000101473 Acyl-CoA thioesterase 8 20 45841721-45857406 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010261 Approved Supported Vesicles
Mitochondria Renal cancer:3.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 30.1 ACOT9 ACATE2, CGI-16, MT-ACT48 ENSG00000123130 Acyl-CoA thioesterase 9 X 23702253-23766475 Predicted intracellular proteins Evidence at protein level HPA035533 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:3.23e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 46.3 ACOX1 PALMCOX ENSG00000161533 Acyl-CoA oxidase 1, palmitoyl 17 75941507-75979363 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB021094, HPA021192, HPA021195, HPA028759 Approved Validated Nucleus
Vesicles Renal cancer:5.25e-7 (favourable) Expressed in all Expressed in all liver: 98.4 ACOX3 ENSG00000087008 Acyl-CoA oxidase 3, pristanoyl 4 8366282-8440723 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035840, HPA035841 Uncertain Approved Peroxisomes Endometrial cancer:2.16e-4 (favourable) Expressed in all Expressed in all esophagus: 22.3 ACP1 HAAP, LMW-PTP ENSG00000143727 Acid phosphatase 1, soluble 2 264140-278283 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016754 Approved Approved Nucleus
Cytosol Liver cancer:6.67e-6 (unfavourable), Melanoma:3.04e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 129.4 ACP2 LAP ENSG00000134575 Acid phosphatase 2, lysosomal 11 47239302-47248906 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:1.04e-4 (favourable) Expressed in all Expressed in all duodenum: 42.4 ACP6 ACPL1, LPAP ENSG00000162836 Acid phosphatase 6, lysophosphatidic 1 147629652-147670496 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028560 Uncertain Urothelial cancer:6.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.5 ACSF3 ENSG00000176715 Acyl-CoA synthetase family member 3 16 89088375-89155846 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:5.97e-6 (favourable), Pancreatic cancer:3.76e-5 (favourable) Expressed in all Expressed in all duodenum: 31.9 ACSL1 ACS1, FACL1, FACL2, LACS, LACS1, LACS2 ENSG00000151726 Acyl-CoA synthetase long-chain family member 1 4 184755595-184826818 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011316, HPA011964 Supported Supported Nucleus
Mitochondria Renal cancer:1.25e-5 (favourable) Expressed in all Expressed in all adipose tissue: 820.6 ACSL3 ACS3, FACL3, PRO2194 ENSG00000123983 Acyl-CoA synthetase long-chain family member 3 2 222860934-222944639 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011315, HPA071021 Uncertain Approved Nucleoli
Lipid droplets Liver cancer:2.75e-4 (unfavourable), Lung cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 670.1 ACSL4 ACS4, FACL4, LACS4, MRX63, MRX68 ENSG00000068366 Acyl-CoA synthetase long-chain family member 4 X 109624244-109733403 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000286, HPA005552 Supported Approved Golgi apparatus
Mitochondria Urothelial cancer:5.73e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 70.3 ACSL5 ACS2, ACS5, FACL5 ENSG00000197142 Acyl-CoA synthetase long-chain family member 5 10 112374018-112428380 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007162, CAB062546 Supported Supported Nucleus
Mitochondria Endometrial cancer:1.13e-4 (favourable) Expressed in all Expressed in all small intestine: 469.9 ACSS1 ACAS2L, AceCS2L, dJ568C11.3, MGC33843 ENSG00000154930 Acyl-CoA synthetase short-chain family member 1 20 25006230-25058980 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041014, HPA043228 Approved Lung cancer:8.33e-5 (favourable), Cervical cancer:9.37e-4 (favourable) Expressed in all Expressed in all placenta: 165.1 ACTA2 ACTSA ENSG00000107796 Actin, alpha 2, smooth muscle, aorta 10 88935074-88991390 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000002, CAB013531, HPA041264, HPA041271 Supported Renal cancer:1.37e-8 (unfavourable) Expressed in all Expressed in all smooth muscle: 11586.2 ACTB ENSG00000075624 Actin, beta 7 5527151-5563784 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002621, HPA041264, HPA041271 Supported Renal cancer:3.78e-5 (unfavourable), Head and neck cancer:4.51e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 7124.7 ACTG1 ACTG, DFNA20, DFNA26 ENSG00000184009 Actin gamma 1 17 81509971-81523847 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041264, HPA041271 Approved Colorectal cancer:2.41e-4 (favourable) Expressed in all Expressed in all ovary: 2398.3 ACTL6A Actl6, Arp4, BAF53A, INO80K ENSG00000136518 Actin-like 6A 3 179562880-179588408 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012188, HPA018671 Supported Validated Nucleoplasm
Cytosol Liver cancer:1.89e-5 (unfavourable), Renal cancer:4.80e-5 (unfavourable), Pancreatic cancer:5.44e-5 (unfavourable) Expressed in all Expressed in all testis: 111.9 ACTN1 ENSG00000072110 Actinin, alpha 1 14 68874143-68979440 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004303, HPA006035 Approved Validated Plasma membrane
Focal adhesion sites Renal cancer:9.08e-10 (unfavourable), Lung cancer:7.63e-5 (unfavourable), Head and neck cancer:2.49e-4 (unfavourable), Urothelial cancer:8.00e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 744.4 ACTN4 FSGS1 ENSG00000130402 Actinin, alpha 4 19 38647649-38731583 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001873, HPA006035 Supported Supported Nuclear bodies
Cytosol Renal cancer:5.25e-5 (favourable), Pancreatic cancer:5.65e-4 (unfavourable), Lung cancer:8.82e-4 (unfavourable) Expressed in all Expressed in all esophagus: 118.9 ACTR1A ARP1, Arp1A ENSG00000138107 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 10 102479229-102502711 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037193, HPA047443 Approved Approved Microtubules Expressed in all Expressed in all cerebral cortex: 114.7 ACTR1B Arp1B, CTRN2 ENSG00000115073 ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 2 97655963-97664107 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047443 Approved Microtubules Urothelial cancer:4.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 80.5 ACTR2 ARP2 ENSG00000138071 ARP2 actin-related protein 2 homolog (yeast) 2 65227753-65271253 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005083, HPA015050 Approved Approved Cytosol Liver cancer:4.50e-4 (unfavourable) Expressed in all Expressed in all appendix: 300.7 ACTR3 ARP3 ENSG00000115091 ARP3 actin-related protein 3 homolog (yeast) 2 113889960-113962596 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005085, HPA047016, HPA051683 Approved Renal cancer:3.81e-5 (unfavourable), Cervical cancer:6.52e-5 (unfavourable), Liver cancer:7.76e-5 (unfavourable) Expressed in all Expressed in all lymph node: 340.2 ACTR3B ARP11, ARP3beta ENSG00000133627 ARP3 actin-related protein 3 homolog B (yeast) 7 152759749-152855378 Predicted intracellular proteins Evidence at protein level HPA047016, HPA051683 Uncertain Renal cancer:1.66e-4 (favourable), Stomach cancer:4.53e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 51.0 ACTR8 INO80N ENSG00000113812 ARP8 actin-related protein 8 homolog (yeast) 3 53867066-53882202 Predicted intracellular proteins Evidence at protein level HPA065236 Supported Nucleus
Centrosome Renal cancer:7.88e-9 (favourable), Liver cancer:5.11e-6 (unfavourable), Colorectal cancer:2.21e-4 (favourable) Expressed in all Expressed in all testis: 39.3 ACVR1 ACVR1A, ACVRLK2, ALK2, SKR1 ENSG00000115170 Activin A receptor, type I 2 157736444-157875862 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007505 Approved Urothelial cancer:5.17e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 73.9 ACVR1B ActRIB, ACVRLK4, ALK4, SKR2 ENSG00000135503 Activin A receptor, type IB 12 51951667-51997078 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026126, HPA063761 Approved Validated Cytosol Expressed in all Expressed in all parathyroid gland: 53.7 ACYP1 ENSG00000119640 Acylphosphatase 1, erythrocyte (common) type 14 75053221-75069483 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034944 Approved Approved Nucleus
Cytosol Liver cancer:6.14e-7 (unfavourable), Breast cancer:1.17e-4 (favourable) Expressed in all Expressed in all adrenal gland: 46.5 ACYP2 ENSG00000170634 Acylphosphatase 2, muscle type 2 53970838-54305300 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035301 Uncertain Approved Nucleoplasm Expressed in all Expressed in all skeletal muscle: 73.8 ADAM10 CD156c, HsT18717, kuz, MADM ENSG00000137845 ADAM metallopeptidase domain 10 15 58588807-58749978 Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB001709, HPA050670 Approved Supported Vesicles
Plasma membrane Lung cancer:8.46e-5 (unfavourable), Pancreatic cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 47.8 ADAM15 MDC15 ENSG00000143537 ADAM metallopeptidase domain 15 1 155050566-155062775 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011633, HPA072878 Uncertain Uncertain Vesicles Renal cancer:5.64e-9 (unfavourable), Glioma:3.49e-5 (unfavourable), Liver cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all skin: 72.8 ADAM17 CD156B, cSVP, TACE ENSG00000151694 ADAM metallopeptidase domain 17 2 9488486-9555792 CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010738, CAB025906, HPA051575 Approved Supported Cytosol Urothelial cancer:4.23e-5 (unfavourable) Expressed in all Expressed in all placenta: 33.9 ADAM9 CORD9, KIAA0021, MCMP, MDC9, Mltng ENSG00000168615 ADAM metallopeptidase domain 9 8 38996869-39105144 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004000 Approved Endoplasmic reticulum
Vesicles Liver cancer:7.21e-6 (unfavourable), Pancreatic cancer:2.52e-5 (unfavourable), Breast cancer:1.14e-4 (unfavourable), Cervical cancer:2.25e-4 (unfavourable), Renal cancer:3.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 116.7 ADAR ADAR1, G1P1, IFI4 ENSG00000160710 Adenosine deaminase, RNA-specific 1 154582062-154627999 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003890, HPA051519, CAB056157 Supported Validated Nucleus
Nucleoli Renal cancer:7.30e-5 (unfavourable) Expressed in all Expressed in all spleen: 122.7 ADARB1 ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2c, ADAR2d, ADAR2g, DRABA2, DRADA2, hRED1, RED1 ENSG00000197381 Adenosine deaminase, RNA-specific, B1 21 45073853-45226560 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018277, HPA029645 Uncertain Supported Nucleoplasm
Cytosol Colorectal cancer:8.16e-5 (unfavourable), Renal cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all lung: 30.3 ADAT1 ENSG00000065457 Adenosine deaminase, tRNA-specific 1 16 75596981-75623300 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040713, HPA040903 Approved Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 89.6 ADCK2 MGC20727 ENSG00000133597 AarF domain containing kinase 2 7 140673153-140696261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036036 Approved Uncertain Centrosome
Cytosol Renal cancer:9.75e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 26.7 ADCK4 COQ8, FLJ12229 ENSG00000123815 AarF domain containing kinase 4 19 40691529-40718207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027229, HPA027277, HPA027279, HPA028303 Supported Validated Mitochondria Expressed in all Expressed in all fallopian tube: 40.7 ADCY3 AC3 ENSG00000138031 Adenylate cyclase 3 2 24819169-24919839 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB010223 Approved Renal cancer:1.32e-9 (unfavourable) Expressed in all Expressed in all placenta: 121.3 ADD1 ENSG00000087274 Adducin 1 (alpha) 4 2843857-2930076 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009794, HPA035873, HPA035874 Supported Validated Nucleoplasm
Plasma membrane Renal cancer:1.29e-7 (favourable), Pancreatic cancer:3.94e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 201.7 ADD3 ADDL ENSG00000148700 Adducin 3 (gamma) 10 109996368-110135565 Predicted intracellular proteins Evidence at protein level CAB009797, HPA035696 Supported Supported Plasma membrane Expressed in all Expressed in all thyroid gland: 167.8 ADGRA2 DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5 ENSG00000020181 Adhesion G protein-coupled receptor A2 8 37784191-37844896 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012393 Uncertain Renal cancer:3.18e-7 (unfavourable) Expressed in all Expressed in all seminal vesicle: 86.1 ADGRA3 FLJ38547, GPR125, PGR21 ENSG00000152990 Adhesion G protein-coupled receptor A3 4 22345071-22516054 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008904 Uncertain Expressed in all Expressed in all thyroid gland: 42.3 ADGRE5 CD97, TM7LN1 ENSG00000123146 Adhesion G protein-coupled receptor E5 19 14380501-14408725 CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA013707 Supported Approved Cytosol Renal cancer:1.87e-6 (unfavourable), Liver cancer:3.73e-5 (unfavourable) Expressed in all Expressed in all spleen: 142.8 ADGRG1 GPR56, TM7LN4, TM7XN1 ENSG00000205336 Adhesion G protein-coupled receptor G1 16 57610652-57665580 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046065 Uncertain Renal cancer:5.52e-7 (favourable), Head and neck cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 348.2 ADH5 ADH-3, ADHX, FDH ENSG00000197894 Alcohol dehydrogenase 5 (class III), chi polypeptide 4 99070978-99088801 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044578, HPA061919 Approved Renal cancer:4.58e-10 (favourable), Endometrial cancer:9.90e-5 (favourable), Melanoma:3.54e-4 (unfavourable) Expressed in all Expressed in all endometrium: 197.0 ADI1 APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL ENSG00000182551 Acireductone dioxygenase 1 2 3497361-3519736 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035403, HPA035404 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all liver: 228.6 ADIPOR1 ACDCR1, PAQR1 ENSG00000159346 Adiponectin receptor 1 1 202940823-202958572 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Ovarian cancer:5.27e-4 (favourable), Pancreatic cancer:5.50e-4 (unfavourable) Expressed in all Expressed in all placenta: 135.5 ADIPOR2 ACDCR2, PAQR2 ENSG00000006831 Adiponectin receptor 2 12 1688574-1788678 Predicted membrane proteins Evidence at protein level HPA043737 Approved Expressed in all Expressed in all adipose tissue: 76.9 ADK AK ENSG00000156110 Adenosine kinase 10 74151185-74709303 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB032876, HPA038391, HPA038409 Approved Supported Nucleoplasm
Cytosol Head and neck cancer:1.93e-4 (unfavourable), Liver cancer:9.91e-4 (favourable) Expressed in all Expressed in all liver: 77.4 ADM AM ENSG00000148926 Adrenomedullin 11 10304680-10307397 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016075 Approved Renal cancer:6.33e-4 (unfavourable), Liver cancer:7.56e-4 (unfavourable) Expressed in all Expressed in all placenta: 157.8 ADNP ADNP1, KIAA0784 ENSG00000101126 Activity-dependent neuroprotector homeobox 20 50888919-50931240 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006371 Supported Approved Nucleoplasm Liver cancer:1.65e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 80.3 ADO C10orf22, FLJ14547 ENSG00000181915 2-aminoethanethiol (cysteamine) dioxygenase 10 62804857-62808483 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039194, HPA040437 Approved Liver cancer:8.01e-5 (unfavourable) Expressed in all Expressed in all testis: 70.2 ADPRHL2 ARH3, FLJ20446 ENSG00000116863 ADP-ribosylhydrolase like 2 1 36088875-36093932 Enzymes, Predicted secreted proteins Evidence at protein level HPA027104, HPA027141 Approved Validated Nucleoplasm Liver cancer:2.10e-7 (unfavourable), Renal cancer:3.71e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 40.7 ADPRM C17orf48, MDS006 ENSG00000170222 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 17 10697594-10711233 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023265, HPA023820 Approved Endometrial cancer:2.38e-5 (favourable), Cervical cancer:1.69e-4 (favourable) Expressed in all Expressed in all prostate: 18.1 ADRBK1 BARK1, GRK2 ENSG00000173020 Adrenergic, beta, receptor kinase 1 11 67266410-67286556 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005021, CAB037248, HPA048330 Approved Approved Vesicles Renal cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all spleen: 129.5 ADRM1 ARM1, GP110, Rpn13 ENSG00000130706 Adhesion regulating molecule 1 20 62302093-62308862 Predicted intracellular proteins Evidence at protein level HPA042266 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:9.02e-6 (unfavourable) Expressed in all Expressed in all testis: 108.8 ADSL ENSG00000239900 Adenylosuccinate lyase 22 40346500-40369367 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000525, CAB019285 Supported Validated Cytosol Liver cancer:5.81e-8 (unfavourable), Colorectal cancer:2.38e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 118.1 ADSS ENSG00000035687 Adenylosuccinate synthase 1 244408494-244452134 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024400 Supported Supported Plasma membrane
Cytosol Expressed in all Expressed in all testis: 116.4 AEBP1 ACLP ENSG00000106624 AE binding protein 1 7 44104361-44114562 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB009966, HPA047724, HPA063595, HPA064970 Supported Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:9.31e-9 (unfavourable), Glioma:1.10e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 297.8 AEBP2 MGC17922 ENSG00000139154 AE binding protein 2 12 19404045-19720801 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020893, HPA022282 Uncertain Supported Nucleus Liver cancer:3.24e-4 (unfavourable) Expressed in all Expressed in all placenta: 57.6 AES GRG5, TLE5 ENSG00000104964 Amino-terminal enhancer of split 19 3052910-3063107 Predicted intracellular proteins Evidence at protein level HPA049499 Approved Nucleoplasm Endometrial cancer:3.89e-4 (favourable), Renal cancer:7.74e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 332.3 AF011889.5 ENSG00000241489 X 149482543-149533935 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all epididymis: 64.5 AFF1 AF-4, AF4, MLLT2, PBM1 ENSG00000172493 AF4/FMR2 family, member 1 4 86935002-87141054 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA069947 Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all thyroid gland: 91.1 AFF4 AF5Q31, MCEF ENSG00000072364 AF4/FMR2 family, member 4 5 132875379-132963634 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023690, HPA029634 Approved Supported Nucleus
Nucleoli fibrillar center Thyroid cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.0 AFG3L2 SCA28, SPAX5 ENSG00000141385 AFG3-like AAA ATPase 2 18 12328944-12377314 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA004479, HPA004480 Supported Validated Mitochondria Renal cancer:6.05e-14 (favourable), Endometrial cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 121.6 AFMID DKFZp686F03259, KF ENSG00000183077 Arylformamidase 17 78187317-78207701 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023861, HPA026536 Uncertain Approved Mitochondria Expressed in all Expressed in all kidney: 87.0 AFTPH FLJ20080, FLJ23793, MGC33965, Nbla10388 ENSG00000119844 Aftiphilin 2 64524305-64593005 Predicted intracellular proteins Evidence at protein level HPA034990, HPA034991 Approved Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:2.37e-5 (favourable), Urothelial cancer:1.83e-4 (favourable), Stomach cancer:8.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 64.5 AGA ASRG ENSG00000038002 Aspartylglucosaminidase 4 177430770-177442503 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031415, HPA031417 Supported Liver cancer:1.99e-4 (unfavourable), Head and neck cancer:8.61e-4 (unfavourable) Expressed in all Expressed in all epididymis: 34.7 AGAP1 CENTG2, GGAP1, KIAA1099 ENSG00000157985 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2 235494089-236131800 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051405 Uncertain Liver cancer:2.60e-5 (unfavourable), Renal cancer:6.52e-5 (favourable), Ovarian cancer:9.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.6 AGAP3 CENTG3 ENSG00000133612 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 7 151085831-151144436 Predicted intracellular proteins Evidence at protein level HPA012883 Approved Renal cancer:8.58e-5 (unfavourable), Liver cancer:6.21e-4 (unfavourable), Colorectal cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 92.8 AGAP4 AGAP8, CTGLF1, CTGLF5, Em:AC012044.1, MRIP2 ENSG00000188234 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 10 45825594-45853875 Predicted intracellular proteins Evidence at transcript level HPA042490 Uncertain Mixed Expressed in all skin: 24.6 AGAP6 bA324H6.1, CTGLF3 ENSG00000204149 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 10 49982190-50010499 Predicted intracellular proteins Evidence at transcript level HPA042490 Uncertain Renal cancer:9.70e-10 (unfavourable), Urothelial cancer:1.83e-7 (favourable), Pancreatic cancer:2.66e-4 (favourable) Expressed in all Expressed in all skin: 21.9 AGAP9 bA301J7.2, CTGLF6, FLJ00312 ENSG00000204172 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 10 47501854-47523638 Predicted intracellular proteins Evidence at transcript level HPA042490 Uncertain Renal cancer:3.02e-5 (unfavourable), Colorectal cancer:9.98e-5 (unfavourable), Urothelial cancer:7.04e-4 (favourable) Expressed in all Expressed in all skin: 26.4 AGFG1 HRB, RAB, RIP ENSG00000173744 ArfGAP with FG repeats 1 2 227472152-227561214 Predicted intracellular proteins Evidence at protein level HPA008741 Approved Supported Vesicles Liver cancer:7.31e-6 (unfavourable), Ovarian cancer:3.43e-5 (unfavourable), Lung cancer:1.85e-4 (unfavourable), Renal cancer:6.92e-4 (unfavourable), Cervical cancer:7.13e-4 (unfavourable), Glioma:7.89e-4 (favourable) Expressed in all Expressed in all testis: 168.4 AGGF1 FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q ENSG00000164252 Angiogenic factor with G patch and FHA domains 1 5 77029251-77065234 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043500 Uncertain Colorectal cancer:2.87e-4 (favourable) Expressed in all Expressed in all testis: 33.7 AGK FLJ10842, MULK ENSG00000006530 Acylglycerol kinase 7 141551189-141655244 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020959, HPA053471 Supported Supported Vesicles
Mitochondria Expressed in all Expressed in all parathyroid gland: 24.8 AGO1 EIF2C1, hAGO1 ENSG00000092847 Argonaute RISC catalytic component 1 1 35869808-35930528 Predicted intracellular proteins Evidence at protein level Liver cancer:4.57e-5 (unfavourable), Renal cancer:2.60e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 15.8 AGO2 EIF2C2, hAGO2, Q10 ENSG00000123908 Argonaute RISC catalytic component 2 8 140520156-140635619 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB019309, HPA058075 Approved Supported Nucleoplasm
Cell Junctions Renal cancer:1.82e-5 (unfavourable), Endometrial cancer:1.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 11.9 AGO4 EIF2C4, FLJ20033, hAGO4, KIAA1567 ENSG00000134698 Argonaute RISC catalytic component 4 1 35808172-35857890 Predicted intracellular proteins Evidence at protein level CAB012179, HPA068896 Approved Validated Nucleoplasm
Nuclear bodies
Cytosol Head and neck cancer:5.70e-5 (favourable) Expressed in all Expressed in all skin: 24.5 AGPAT2 BSCL, LPAAT-beta ENSG00000169692 1-acylglycerol-3-phosphate O-acyltransferase 2 9 136673143-136687423 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA019544 Uncertain Approved Centrosome Expressed in all Expressed in all adipose tissue: 299.8 AGPAT3 LPAAT-gamma ENSG00000160216 1-acylglycerol-3-phosphate O-acyltransferase 3 21 43865186-43986536 Enzymes, Predicted membrane proteins Evidence at protein level Renal cancer:2.29e-4 (favourable), Cervical cancer:8.31e-4 (unfavourable) Expressed in all Expressed in all small intestine: 58.7 AGPAT5 FLJ11210, LPAAT-e, LPAAT-epsilon ENSG00000155189 1-acylglycerol-3-phosphate O-acyltransferase 5 8 6708357-6759666 Enzymes, Predicted membrane proteins Evidence at protein level HPA010644, HPA010950 Approved Liver cancer:4.57e-4 (unfavourable), Colorectal cancer:8.82e-4 (favourable) Expressed in all Expressed in all testis: 46.7 AGPS ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY ENSG00000018510 Alkylglycerone phosphate synthase 2 177392644-177543836 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA030209, HPA030210, HPA030211 Supported Validated Peroxisomes Liver cancer:8.62e-6 (unfavourable), Pancreatic cancer:8.35e-4 (unfavourable), Renal cancer:9.45e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.2 AGRN AGRIN ENSG00000188157 Agrin 1 1020123-1056118 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040090 Approved Supported Plasma membrane
Cytosol Liver cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 29.4 AGTPBP1 CCP1, KIAA1035, Nna1 ENSG00000135049 ATP/GTP binding protein 1 9 85546539-85742029 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA057208 Approved Approved Nucleoli
Vesicles Expressed in all Expressed in all bone marrow: 39.3 AGTRAP ATRAP ENSG00000177674 Angiotensin II receptor-associated protein 1 11736084-11754802 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA044120 Approved Supported Vesicles Liver cancer:6.57e-7 (unfavourable) Expressed in all Expressed in all prostate: 88.0 AHCTF1 ELYS ENSG00000153207 AT hook containing transcription factor 1 1 246839098-246931978 Predicted intracellular proteins, Transporters Evidence at protein level HPA031658 Uncertain Supported Nuclear membrane Renal cancer:3.49e-8 (unfavourable) Expressed in all Expressed in all testis: 61.2 AHCY SAHH ENSG00000101444 Adenosylhomocysteinase 20 34280268-34311802 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041225, HPA044675 Approved Supported Cytosol Expressed in all Expressed in all thyroid gland: 158.6 AHCYL1 IRBIT, PPP1R78, XPVKONA ENSG00000168710 Adenosylhomocysteinase-like 1 1 109984686-110023741 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042589 Approved Supported Cytosol Colorectal cancer:7.00e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 254.6 AHCYL2 KIAA0828 ENSG00000158467 Adenosylhomocysteinase-like 2 7 129225023-129430211 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053128 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.08e-7 (favourable), Head and neck cancer:4.17e-4 (favourable) Expressed in all Expressed in all rectum: 198.1 AHNAK MGC5395 ENSG00000124942 AHNAK nucleoprotein 11 62433542-62556235 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019010, HPA019070, HPA026643 Uncertain Supported Plasma membrane
Cytosol Urothelial cancer:3.47e-6 (unfavourable), Pancreatic cancer:2.42e-4 (unfavourable) Expressed in all Expressed in all skin: 398.0 AHSA1 Aha1, C14orf3, p38 ENSG00000100591 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 14 77457870-77469474 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000903, CAB006244 Supported Supported Cytosol Liver cancer:5.04e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 178.7 AHSA2 DKFZp564C236, Hch1 ENSG00000173209 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) 2 61177418-61191203 Predicted intracellular proteins Evidence at protein level HPA051137 Approved Approved Vesicles
Microtubules
Cytokinetic bridge Renal cancer:4.11e-6 (unfavourable), Urothelial cancer:1.85e-4 (favourable) Expressed in all Expressed in all spleen: 41.9 AIDA C1orf80, FLJ12806 ENSG00000186063 Axin interactor, dorsalization associated 1 222668013-222713210 Predicted intracellular proteins Evidence at protein level HPA027935 Approved Approved Microtubules
Cytokinetic bridge
Cytosol Cervical cancer:7.08e-5 (unfavourable), Renal cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 79.9 AIFM1 AIF, CMTX4, NAMSD, PDCD8 ENSG00000156709 Apoptosis-inducing factor, mitochondrion-associated, 1 X 130129362-130165887 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB003764, HPA030611 Supported Renal cancer:4.42e-10 (favourable) Expressed in all Expressed in all kidney: 156.9 AIG1 AIG-1, dJ95L4.1, FLJ10485 ENSG00000146416 Androgen-induced 1 6 143060496-143340304 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA060766 Approved Approved Golgi apparatus Head and neck cancer:3.25e-7 (unfavourable), Cervical cancer:3.26e-6 (unfavourable), Endometrial cancer:3.06e-4 (unfavourable) Expressed in all Expressed in all liver: 153.9 AIMP1 EMAP-2, EMAPII, p43, SCYE1 ENSG00000164022 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 4 106315544-106349226 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB017618, HPA018476 Supported Validated Cytosol Head and neck cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 63.0 AIMP2 JTV-1, JTV1, p38, PRO0992 ENSG00000106305 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 7 6009245-6023834 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019098, HPA020057 Supported Approved Cytosol Renal cancer:1.38e-5 (favourable), Urothelial cancer:3.09e-4 (unfavourable), Head and neck cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all testis: 60.7 AIP ARA9, FKBP16, XAP2 ENSG00000110711 Aryl hydrocarbon receptor interacting protein 11 67483041-67491103 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033674, HPA050217, CAB069477 Approved Supported Cytosol Colorectal cancer:1.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 102.2 AK1 ENSG00000106992 Adenylate kinase 1 9 127866480-127877743 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006456, CAB009893 Supported Supported Cytosol Stomach cancer:7.31e-4 (favourable) Expressed in all Expressed in all fallopian tube: 764.1 AK2 ENSG00000004455 Adenylate kinase 2 1 33007940-33080996 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018479 Approved Breast cancer:4.37e-4 (favourable), Pancreatic cancer:6.40e-4 (unfavourable), Endometrial cancer:8.65e-4 (unfavourable), Liver cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all kidney: 182.0 AK3 AK3L1, AK6, AKL3L1 ENSG00000147853 Adenylate kinase 3 9 4709559-4742043 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063324 Supported Supported Mitochondria Renal cancer:6.07e-9 (favourable) Expressed in all Expressed in all kidney: 105.9 AK6 CINAP ENSG00000085231 Adenylate kinase 6 5 69350984-69370013 Enzymes, Predicted intracellular proteins Evidence at protein level CAB005361, HPA034935 Supported Supported Nucleoplasm Liver cancer:9.54e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 25.2 AKAP1 AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17 ENSG00000121057 A kinase (PRKA) anchor protein 1 17 57085092-57121349 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008620, HPA008691, CAB019286 Supported Supported Mitochondria Renal cancer:7.86e-9 (favourable) Expressed in all Expressed in all testis: 149.4 AKAP10 D-AKAP2, MGC9414, PRKA10 ENSG00000108599 A kinase (PRKA) anchor protein 10 17 19904302-19978343 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028901 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all testis: 26.1 AKAP11 AKAP220, DKFZp781I12161, FLJ11304, KIAA0629, PPP1R44, PRKA11 ENSG00000023516 A kinase (PRKA) anchor protein 11 13 42272153-42323267 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039089 Supported Approved Nucleoli
Plasma membrane
Cytosol Cervical cancer:9.26e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 51.7 AKAP12 AKAP250, SSeCKS ENSG00000131016 A kinase (PRKA) anchor protein 12 6 151239999-151358557 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006344, CAB026379, HPA056230 Supported Supported Plasma membrane
Cytosol Lung cancer:6.34e-5 (unfavourable), Endometrial cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all testis: 183.8 AKAP13 AKAP-Lbc, ARHGEF13, BRX, c-lbc, HA-3, Ht31, LBC, PROTO-LB ENSG00000170776 A kinase (PRKA) anchor protein 13 15 85380571-85749358 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019773 Approved Supported Cytosol Expressed in all Expressed in all endometrium: 74.2 AKAP17A 721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y ENSG00000197976 A kinase (PRKA) anchor protein 17A X 1591593-1602514 Predicted intracellular proteins Evidence at protein level HPA043247, HPA051020 Supported Supported Nuclear speckles
Cytosol Renal cancer:3.52e-7 (unfavourable), Urothelial cancer:1.11e-5 (favourable), Pancreatic cancer:2.42e-4 (favourable), Endometrial cancer:3.40e-4 (favourable) Expressed in all Expressed in all spleen: 61.7 AKAP2 AKAP-KL, DKFZp564L0716, KIAA0920, PRKA2 ENSG00000241978 A kinase (PRKA) anchor protein 2 9 110048598-110172512 Predicted intracellular proteins Evidence at protein level Not detected Expressed in all placenta: 122.9 AKAP7 AKAP15, AKAP18 ENSG00000118507 A kinase (PRKA) anchor protein 7 6 131135666-131283535 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027172, HPA028327 Supported Urothelial cancer:2.56e-4 (favourable) Expressed in all Expressed in all adrenal gland: 72.9 AKAP8 AKAP95, DKFZp586B1222 ENSG00000105127 A kinase (PRKA) anchor protein 8 19 15353385-15379798 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004776 Supported Supported Nucleoplasm Expressed in all Expressed in all bone marrow: 13.1 AKAP8L HAP95, NAKAP95 ENSG00000011243 A kinase (PRKA) anchor protein 8-like 19 15380048-15419141 Predicted intracellular proteins Evidence at protein level HPA042485, HPA042546 Supported Supported Nuclear speckles Renal cancer:1.08e-7 (unfavourable), Colorectal cancer:3.49e-4 (unfavourable), Pancreatic cancer:8.04e-4 (favourable) Expressed in all Expressed in all testis: 41.5 AKAP9 AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO ENSG00000127914 A kinase (PRKA) anchor protein 9 7 91940867-92110673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008548, CAB012909, HPA026109 Supported Validated Golgi apparatus
Vesicles
Centrosome Renal cancer:2.10e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 37.2 AKIP1 BCA3, C11orf17 ENSG00000166452 A kinase (PRKA) interacting protein 1 11 8911139-8920084 Predicted intracellular proteins Evidence at protein level HPA061391 Supported Nucleoplasm Liver cancer:6.24e-9 (unfavourable), Endometrial cancer:5.15e-4 (favourable) Expressed in all Expressed in all adrenal gland: 30.7 AKIRIN1 C1orf108, FLJ12666 ENSG00000174574 Akirin 1 1 38991223-39006059 Predicted intracellular proteins Evidence at protein level HPA051871 Approved Supported Nucleoplasm
Nuclear membrane Liver cancer:5.39e-7 (unfavourable) Expressed in all Expressed in all testis: 127.4 AKIRIN2 C6orf166, dJ486L4.2, FLJ10342 ENSG00000135334 Akirin 2 6 87675072-87702209 Predicted intracellular proteins Evidence at protein level HPA064239 Supported Nucleoplasm Expressed in all Expressed in all spleen: 59.2 AKR1A1 ALR, DD3 ENSG00000117448 Aldo-keto reductase family 1, member A1 (aldehyde reductase) 1 45550543-45570049 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB006246, HPA017919, HPA019649, HPA027734 Approved Supported Nucleoplasm
Cytosol Cervical cancer:2.66e-6 (favourable), Endometrial cancer:2.92e-4 (favourable) Expressed in all Expressed in all kidney: 377.7 AKR1C1 DD1, DDH, DDH1, HAKRC, MBAB ENSG00000187134 Aldo-keto reductase family 1, member C1 10 4963253-5107522 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB047303, HPA068265 Uncertain Supported Endoplasmic reticulum
Cytosol Renal cancer:8.03e-9 (favourable), Liver cancer:1.56e-4 (unfavourable), Cervical cancer:3.05e-4 (favourable) Tissue enhanced Expressed in all liver: 406.4 AKR1C3 DDX, HAKRB, HSD17B5, KIAA0119, PGFS ENSG00000196139 Aldo-keto reductase family 1, member C3 10 5035354-5107686 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010874, HPA068265 Approved Approved Nucleus
Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Renal cancer:1.22e-4 (unfavourable), Liver cancer:1.96e-4 (unfavourable) Expressed in all Expressed in all duodenum: 154.7 AKR7A2 AFAR ENSG00000053371 Aldo-keto reductase family 7, member A2 1 19303965-19312146 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032587, CAB032841, HPA064638 Supported Supported Cytosol Renal cancer:2.67e-4 (favourable), Urothelial cancer:8.59e-4 (unfavourable) Expressed in all Expressed in all duodenum: 84.1 AKT1 AKT, PKB, PRKBA, RAC ENSG00000142208 V-akt murine thymoma viral oncogene homolog 1 14 104769349-104795751 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA002891, CAB003765 Supported Supported Nucleus
Microtubules Renal cancer:2.12e-4 (favourable), Ovarian cancer:4.83e-4 (favourable) Expressed in all Expressed in all lung: 104.6 AKT1S1 Lobe, MGC2865, PRAS40 ENSG00000204673 AKT1 substrate 1 (proline-rich) 19 49869033-49878459 Predicted intracellular proteins Evidence at protein level CAB021903, HPA043590, HPA064427 Uncertain Supported Cytosol Renal cancer:7.34e-6 (unfavourable), Liver cancer:3.70e-4 (unfavourable), Pancreatic cancer:6.60e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 33.9 AKT2 ENSG00000105221 V-akt murine thymoma viral oncogene homolog 2 19 40230317-40285536 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004204, HPA064521 Uncertain Supported Nucleus
Vesicles
Cytosol Endometrial cancer:1.05e-6 (unfavourable), Prostate cancer:4.74e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 169.5 AKTIP FLJ13258, FTS ENSG00000166971 AKT interacting protein 16 53491040-53504411 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041794, HPA046300 Approved Renal cancer:1.18e-14 (favourable) Expressed in all Expressed in all testis: 81.0 AL135745.1 ENSG00000279654 14 64894339-64894713 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Mixed Expressed in all skin: 37.7 AL136097.1 ENSG00000279007 9 92227001-92227375 Predicted intracellular proteins Evidence at transcript level HPA042797 Uncertain Not detected Expressed in all testis: 45.1 AL592183.1 ENSG00000273748 Unmapped 54224-83311 Predicted intracellular proteins Evidence at transcript level HPA049380 Approved Expressed in all gallbladder: 147.9 ALAD ALADH, PBGS ENSG00000148218 Aminolevulinate dehydratase 9 113386317-113401333 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021023, HPA022124 Supported Colorectal cancer:7.33e-5 (unfavourable), Liver cancer:8.80e-5 (favourable), Renal cancer:1.65e-4 (favourable), Endometrial cancer:5.64e-4 (favourable) Expressed in all Expressed in all adrenal gland: 147.9 ALAS1 ALAS, ALAS3 ENSG00000023330 5'-aminolevulinate synthase 1 3 52198086-52214327 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017498, HPA035860 Supported Validated Nucleoplasm
Mitochondria Renal cancer:6.06e-7 (favourable), Liver cancer:1.82e-5 (favourable) Expressed in all Expressed in all adrenal gland: 765.5 ALDH16A1 MGC10204 ENSG00000161618 Aldehyde dehydrogenase 16 family, member A1 19 49453169-49471048 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA059488 Approved Supported Mitochondria Expressed in all Expressed in all spleen: 17.9 ALDH18A1 GSAS, P5CS, PYCS ENSG00000059573 Aldehyde dehydrogenase 18 family, member A1 10 95605929-95656706 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008333, HPA012604 Approved Validated Mitochondria Renal cancer:3.60e-9 (unfavourable), Endometrial cancer:4.20e-4 (favourable) Expressed in all Expressed in all duodenum: 92.0 ALDH1A1 ALDH1, PUMB1, RALDH1 ENSG00000165092 Aldehyde dehydrogenase 1 family, member A1 9 72900662-73080442 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002123, CAB020690 Approved Approved Validated Cytosol Cervical cancer:7.77e-5 (favourable) Expressed in all Expressed in all liver: 758.5 ALDH1B1 ALDH5, ALDHX ENSG00000137124 Aldehyde dehydrogenase 1 family, member B1 9 38392664-38398661 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021037 Approved Supported Nucleoplasm
Vesicles
Mitochondria Thyroid cancer:1.17e-5 (unfavourable), Renal cancer:2.05e-4 (favourable) Expressed in all Expressed in all smooth muscle: 176.4 ALDH2 ENSG00000111275 Aldehyde dehydrogenase 2 family (mitochondrial) 12 111766887-111817529 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051065 Approved Liver cancer:3.95e-7 (favourable), Renal cancer:5.24e-6 (favourable), Endometrial cancer:2.63e-4 (favourable), Urothelial cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all liver: 440.7 ALDH3A2 ALDH10, ALDH3A2, FALDH , SLS ENSG00000072210 Aldehyde dehydrogenase 3 family, member A2 17 19648136-19677598 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014769, CAB020692 Approved Renal cancer:3.85e-8 (favourable) Expressed in all Expressed in all adrenal gland: 179.9 ALDH5A1 SSADH, SSDH ENSG00000112294 Aldehyde dehydrogenase 5 family, member A1 6 24494852-24537207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029715, HPA029716 Supported Validated Mitochondria Liver cancer:7.61e-6 (favourable), Renal cancer:3.68e-4 (favourable), Ovarian cancer:6.20e-4 (favourable) Expressed in all Expressed in all liver: 46.8 ALDH6A1 MMSDH ENSG00000119711 Aldehyde dehydrogenase 6 family, member A1 14 74056850-74084493 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029072, HPA029073, HPA029074, HPA029075 Supported Validated Mitochondria Renal cancer:2.00e-15 (favourable), Lung cancer:4.22e-4 (favourable) Expressed in all Expressed in all kidney: 386.6 ALDH7A1 ATQ1, EPD, PDE ENSG00000164904 Aldehyde dehydrogenase 7 family, member A1 5 126541841-126595418 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023296 Supported Supported Mitochondria
Cytosol Renal cancer:3.08e-4 (favourable) Expressed in all Expressed in all kidney: 162.4 ALDH9A1 ALDH4, ALDH7, ALDH9, E3 ENSG00000143149 Aldehyde dehydrogenase 9 family, member A1 1 165662216-165698863 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA006077, HPA010873 Approved Approved Cytosol Pancreatic cancer:4.56e-4 (favourable) Expressed in all Expressed in all thyroid gland: 205.3 ALG1 HMAT1, HMT-1 ENSG00000033011 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 16 5033960-5087379 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA060392 Approved Approved Nucleoli fibrillar center
Endoplasmic reticulum Colorectal cancer:5.79e-4 (favourable), Testis cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 32.8 ALG11 KIAA0266 ENSG00000253710 ALG11, alpha-1,2-mannosyltransferase 13 52012398-52029664 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047214 Approved Mixed Expressed in all thyroid gland: 23.4 ALG12 ECM39 ENSG00000182858 ALG12, alpha-1,6-mannosyltransferase 22 49900229-49918458 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA003076, HPA051665 Approved Approved Endoplasmic reticulum Renal cancer:3.60e-5 (favourable), Endometrial cancer:6.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 17.1 ALG13 CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W ENSG00000101901 ALG13, UDP-N-acetylglucosaminyltransferase subunit X 111665811-111760649 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002853 Approved Renal cancer:1.10e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 30.3 ALG2 CDGIi, FLJ14511, hALPG2, NET38 ENSG00000119523 ALG2, alpha-1,3/1,6-mannosyltransferase 9 99216426-99221956 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041512, HPA041601 Approved Validated Actin filaments
Cytosol Renal cancer:2.28e-7 (favourable), Endometrial cancer:8.44e-5 (favourable), Head and neck cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all epididymis: 75.8 ALG3 CDGS4, D16Ertd36e, Not56, NOT56L ENSG00000214160 ALG3, alpha-1,3- mannosyltransferase 3 184242301-184249548 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA045103 Approved Liver cancer:1.58e-5 (unfavourable), Lung cancer:8.67e-5 (unfavourable), Renal cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 32.7 ALG5 bA421P11.2 ENSG00000120697 ALG5, dolichyl-phosphate beta-glucosyltransferase 13 36949775-37000261 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007989 Approved Approved Cytosol Renal cancer:1.40e-5 (favourable), Head and neck cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 96.2 ALG8 MGC2840 ENSG00000159063 ALG8, alpha-1,3-glucosyltransferase 11 78100936-78139660 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA051898 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 85.6 ALG9 DIBD1 ENSG00000086848 ALG9, alpha-1,2-mannosyltransferase 11 111782195-111871581 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA038575 Approved Approved Endoplasmic reticulum Renal cancer:7.29e-5 (unfavourable) Expressed in all Expressed in all testis: 25.3 ALKBH2 ABH2, MGC90512 ENSG00000189046 AlkB homolog 2, alpha-ketoglutarate-dependent dioxygenase 12 109088188-109093631 Enzymes, Predicted intracellular proteins Evidence at protein level CAB011198, HPA045392, HPA051976 Approved Validated Nucleus Renal cancer:1.41e-5 (unfavourable), Breast cancer:6.67e-5 (favourable), Urothelial cancer:8.67e-4 (favourable) Expressed in all Expressed in all skin: 27.1 ALKBH3 DEPC-1 ENSG00000166199 AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase 11 43880811-43920266 Predicted intracellular proteins Evidence at protein level HPA009674, HPA046489 Approved Validated Nucleoplasm
Mitochondria Expressed in all Expressed in all epididymis: 31.9 ALKBH4 FLJ20013 ENSG00000160993 AlkB homolog 4, lysine demthylase 7 102456238-102464876 Predicted intracellular proteins Evidence at protein level HPA051422 Approved Renal cancer:3.09e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 10.1 ALKBH5 FLJ20308, OFOXD1 ENSG00000091542 AlkB homolog 5, RNA demethylase 17 18183078-18209954 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007196 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Pancreatic cancer:3.75e-4 (favourable), Urothelial cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all testis: 110.7 ALKBH7 MGC10974, SPATA11 ENSG00000125652 AlkB homolog 7 19 6372433-6375251 Predicted intracellular proteins Evidence at protein level HPA039571, HPA039872 Supported Renal cancer:7.83e-6 (favourable) Expressed in all Expressed in all testis: 252.8 ALOX5AP FLAP ENSG00000132965 Arachidonate 5-lipoxygenase-activating protein 13 30713478-30764426 Disease related genes, Predicted membrane proteins Evidence at protein level HPA026592 Supported Renal cancer:5.68e-4 (unfavourable), Ovarian cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 302.3 ALS2 ALS2CR6 ENSG00000003393 Amyotrophic lateral sclerosis 2 (juvenile) 2 201700554-201781189 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046588 Approved Approved Intermediate filaments
Cytosol Expressed in all Expressed in all cerebral cortex: 16.7 ALYREF ALY, ALY/REF, BEF, REF, THOC4 ENSG00000183684 Aly/REF export factor 17 81887844-81891586 Predicted intracellular proteins Evidence at protein level CAB016281, HPA019799, HPA061282 Supported Validated Nuclear speckles Liver cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all testis: 88.5 AMACR RACE ENSG00000242110 Alpha-methylacyl-CoA racemase 5 33986178-34008108 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB001809, HPA019527, HPA020912 Supported Supported Vesicles
Plasma membrane Colorectal cancer:7.11e-4 (favourable) Expressed in all Expressed in all kidney: 134.0 AMBRA1 DCAF3, FLJ20294, KIAA1736, WDR94 ENSG00000110497 Autophagy/beclin-1 regulator 1 11 46396414-46594125 Predicted intracellular proteins Evidence at protein level CAB017825, HPA038535 Approved Approved Vesicles
Mitochondria Renal cancer:1.61e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.6 AMD1 SAMDC ENSG00000123505 Adenosylmethionine decarboxylase 1 6 110814621-110895713 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029281, HPA029282 Approved Approved Nucleoplasm Liver cancer:1.91e-6 (unfavourable), Breast cancer:3.87e-4 (unfavourable), Renal cancer:4.28e-4 (favourable) Expressed in all Expressed in all prostate: 345.5 AMFR gp78, RNF45 ENSG00000159461 Autocrine motility factor receptor, E3 ubiquitin protein ligase 16 56361452-56425538 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026381, HPA029018, HPA077835 Approved Supported Endoplasmic reticulum
Golgi apparatus Expressed in all Expressed in all testis: 154.3 AMMECR1L MGC4268 ENSG00000144233 AMMECR1-like 2 127861630-127885922 Predicted intracellular proteins Evidence at protein level HPA000590, HPA057234 Uncertain Approved Nucleus
Cytosol Endometrial cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all testis: 26.2 AMN1 ENSG00000151743 Antagonist of mitotic exit network 1 homolog 12 31671137-31729174 Predicted intracellular proteins Evidence at protein level HPA046157, HPA062290 Uncertain Approved Centrosome Expressed in all Expressed in all testis: 99.3 AMOTL1 JEAP ENSG00000166025 Angiomotin like 1 11 94706431-94876753 Predicted intracellular proteins Evidence at protein level HPA001196 Approved Supported Cell Junctions
Cytosol Renal cancer:5.03e-6 (favourable) Expressed in all Expressed in all prostate: 52.2 AMPD2 SPG63 ENSG00000116337 Adenosine monophosphate deaminase 2 1 109616104-109632051 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027137, HPA045760, HPA050590 Approved Approved Validated Cytosol Renal cancer:3.78e-10 (unfavourable) Expressed in all Expressed in all bone marrow: 82.5 AMT GCST, NKH ENSG00000145020 Aminomethyltransferase 3 49416778-49422753 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005566 Supported Supported Nucleoplasm
Mitochondria Renal cancer:3.90e-8 (favourable) Expressed in all Expressed in all endometrium: 25.3 AMZ2 ENSG00000196704 Archaelysin family metallopeptidase 2 17 68247574-68257164 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023299, HPA052406 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:1.32e-5 (unfavourable), Renal cancer:3.14e-4 (unfavourable) Expressed in all Expressed in all testis: 355.4 ANAPC1 APC1, MCPR, TSG24 ENSG00000153107 Anaphase promoting complex subunit 1 2 111766271-111884690 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036329, HPA036330, HPA042998 Approved Approved Vesicles Endometrial cancer:1.34e-4 (unfavourable) Expressed in all Expressed in all testis: 20.3 ANAPC10 APC10, DKFZP564L0562, DOC1 ENSG00000164162 Anaphase promoting complex subunit 10 4 144967112-145098541 Predicted intracellular proteins Evidence at protein level HPA044547 Approved Approved Nucleoplasm
Golgi apparatus Melanoma:8.22e-4 (unfavourable) Expressed in all Expressed in all testis: 35.3 ANAPC11 APC11, Apc11p, HSPC214, MGC882 ENSG00000141552 Anaphase promoting complex subunit 11 17 81890790-81900991 Predicted intracellular proteins Evidence at protein level HPA021989, HPA027838 Approved Validated Nucleoplasm
Nucleoli Expressed in all Expressed in all testis: 110.3 ANAPC13 APC13, DKFZP566D193, SWM1 ENSG00000129055 Anaphase promoting complex subunit 13 3 134477706-134486716 Predicted intracellular proteins Evidence at protein level HPA046114 Uncertain Approved Mitochondria
Cytosol Renal cancer:2.66e-7 (favourable), Cervical cancer:1.66e-4 (favourable), Liver cancer:1.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 154.5 ANAPC15 APC15, C11orf51, DKFZP564M082, HSPC020 ENSG00000110200 Anaphase promoting complex subunit 15 11 72106378-72112780 Predicted intracellular proteins Evidence at protein level HPA036596 Approved Approved Nucleoplasm
Vesicles Ovarian cancer:2.55e-4 (favourable), Liver cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 78.0 ANAPC16 APC16, bA570G20.3, C10orf104, CENP-27, FLJ33728 ENSG00000166295 Anaphase promoting complex subunit 16 10 72216000-72235860 Predicted intracellular proteins Evidence at protein level HPA037815 Approved Supported Cytosol Expressed in all Expressed in all thyroid gland: 40.3 ANAPC2 APC2, KIAA1406 ENSG00000176248 Anaphase promoting complex subunit 2 9 137174784-137188549 Predicted intracellular proteins Evidence at protein level CAB018692, HPA066539 Supported Validated Nucleoplasm Pancreatic cancer:1.07e-7 (favourable), Endometrial cancer:8.91e-5 (favourable), Stomach cancer:2.87e-4 (favourable), Renal cancer:3.67e-4 (favourable) Expressed in all Expressed in all testis: 27.1 ANAPC4 APC4 ENSG00000053900 Anaphase promoting complex subunit 4 4 25377213-25418498 Predicted intracellular proteins Evidence at protein level CAB032519, HPA038395, HPA038396 Approved Approved Intermediate filaments Endometrial cancer:5.73e-7 (favourable), Urothelial cancer:1.12e-6 (favourable), Renal cancer:1.17e-5 (unfavourable), Head and neck cancer:1.95e-4 (favourable) Expressed in all Expressed in all fallopian tube: 54.6 ANAPC5 APC5 ENSG00000089053 Anaphase promoting complex subunit 5 12 121308245-121399896 Predicted intracellular proteins Evidence at protein level HPA039457, HPA039801 Supported Approved Nucleoplasm Renal cancer:2.01e-9 (unfavourable), Liver cancer:2.31e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 87.8 ANAPC7 APC7 ENSG00000196510 Anaphase promoting complex subunit 7 12 110372900-110403730 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009567 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.36e-10 (unfavourable), Liver cancer:1.54e-6 (unfavourable) Expressed in all Expressed in all testis: 48.6 ANGEL1 Ccr4e, KIAA0759 ENSG00000013523 Angel homolog 1 (Drosophila) 14 76786178-76826246 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000948 Uncertain Approved Nucleoplasm Lung cancer:3.43e-4 (favourable), Pancreatic cancer:5.46e-4 (favourable) Expressed in all Expressed in all testis: 68.0 ANGEL2 Ccr4d, FLJ12793, KIAA0759L ENSG00000174606 Angel homolog 2 (Drosophila) 1 212992182-213015826 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030796 Uncertain Approved Nucleoplasm
Mitochondria Renal cancer:8.39e-6 (unfavourable), Urothelial cancer:1.20e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 17.0 ANK3 ENSG00000151150 Ankyrin 3, node of Ranvier (ankyrin G) 10 60026298-60733490 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013249, CAB015179, HPA038455, HPA055643 Approved Approved Plasma membrane Renal cancer:8.88e-16 (favourable) Mixed Expressed in all parathyroid gland: 284.5 ANKFY1 ANKHZN, BTBD23, KIAA1255, RANK-5, ZFYVE14 ENSG00000185722 Ankyrin repeat and FYVE domain containing 1 17 4163907-4263977 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024513, HPA024522, HPA065849 Approved Validated Endosomes Expressed in all Expressed in all parathyroid gland: 37.2 ANKH ANK, CCAL2, CMDJ, CPPDD, HANK ENSG00000154122 ANKH inorganic pyrophosphate transport regulator 5 14704804-14871778 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA068104 Approved Cytosol Glioma:7.64e-4 (unfavourable) Expressed in all Expressed in all prostate: 49.5 ANKHD1 FLJ10042, FLJ11979, FLJ14127, FLJ20288, KIAA1085, MASK, MASK1 ENSG00000131503 Ankyrin repeat and KH domain containing 1 5 140401814-140539856 Predicted intracellular proteins Evidence at protein level HPA008718 Approved Mixed Expressed in all parathyroid gland: 73.2 ANKHD1-EIF4EBP3 MASK-BP3 ENSG00000254996 ANKHD1-EIF4EBP3 readthrough 5 140401908-140549569 Predicted intracellular proteins Evidence at transcript level HPA008718 Approved Mixed Expressed in all parathyroid gland: 39.6 ANKIB1 DKFZP434A0225, KIAA1386 ENSG00000001629 Ankyrin repeat and IBR domain containing 1 7 92246234-92401384 Predicted intracellular proteins Evidence at protein level HPA019358, HPA021780 Uncertain Supported Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 45.4 ANKLE2 KIAA0692, Lem4, LEMD7 ENSG00000176915 Ankyrin repeat and LEM domain containing 2 12 132725503-132761888 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003602, HPA074838 Uncertain Supported Endoplasmic reticulum
Plasma membrane Renal cancer:1.90e-8 (unfavourable), Liver cancer:3.97e-6 (unfavourable) Expressed in all Expressed in all testis: 80.1 ANKMY2 DKFZP564O043, ZMYND20 ENSG00000106524 Ankyrin repeat and MYND domain containing 2 7 16599776-16645817 Predicted intracellular proteins Evidence at protein level HPA044900, HPA050447, HPA067100 Approved Nucleoplasm
Cytosol Renal cancer:1.05e-7 (favourable) Expressed in all Expressed in all thyroid gland: 34.4 ANKRA2 ENSG00000164331 Ankyrin repeat, family A (RFXANK-like), 2 5 73552335-73565686 Predicted intracellular proteins Evidence at protein level HPA065263 Approved Plasma membrane
Cell Junctions Expressed in all Expressed in all thyroid gland: 26.1 ANKRD10 FLJ20093 ENSG00000088448 Ankyrin repeat domain 10 13 110878540-110915069 Predicted intracellular proteins Evidence at protein level CAB034211, HPA038878, HPA038879 Uncertain Approved Microtubules
Cytosol Renal cancer:1.25e-6 (unfavourable), Urothelial cancer:6.41e-6 (favourable) Expressed in all Expressed in all epididymis: 107.8 ANKRD11 LZ16, T13 ENSG00000167522 Ankyrin repeat domain 11 16 89267627-89490561 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB019288, HPA041593, HPA049470 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.39e-4 (unfavourable), Prostate cancer:7.67e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 24.4 ANKRD12 FLJ20053, GAC-1, KIAA0874 ENSG00000101745 Ankyrin repeat domain 12 18 9136228-9285985 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA040705 Approved Supported Nucleoplasm
Cytosol Melanoma:6.71e-4 (unfavourable) Expressed in all Expressed in all testis: 54.2 ANKRD13A ANKRD13, NY-REN-25 ENSG00000076513 Ankyrin repeat domain 13A 12 109999186-110039763 Predicted intracellular proteins Evidence at protein level HPA039488, HPA043218 Supported Supported Plasma membrane Head and neck cancer:7.70e-6 (favourable), Ovarian cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all testis: 112.0 ANKRD13C dJ677H15.3, DKFZP566D1346 ENSG00000118454 Ankyrin repeat domain 13C 1 70260588-70354734 Predicted intracellular proteins Evidence at protein level HPA026766 Uncertain Expressed in all Expressed in all parathyroid gland: 18.8 ANKRD13D ENSG00000172932 Ankyrin repeat domain 13 family, member D 11 67288547-67302485 Predicted intracellular proteins Evidence at protein level HPA039950 Approved Approved Nucleus
Mitochondria Renal cancer:5.73e-10 (unfavourable) Expressed in all Expressed in all bone marrow: 69.5 ANKRD17 FLJ22206, GTAR, KIAA0697, MASK2, NY-BR-16 ENSG00000132466 Ankyrin repeat domain 17 4 73073376-73258798 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045024, HPA063731 Approved Supported Nucleus
Nuclear membrane Expressed in all Expressed in all parathyroid gland: 48.8 ANKRD27 DKFZp434L0718, FLJ00040, VARP ENSG00000105186 Ankyrin repeat domain 27 (VPS9 domain) 19 32597007-32676597 Predicted intracellular proteins Evidence at protein level HPA042769 Approved Validated Cytosol Liver cancer:1.21e-5 (unfavourable), Endometrial cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all testis: 32.4 ANKRD28 KIAA0379, PITK, PP6-ARS-A, PPP1R65 ENSG00000206560 Ankyrin repeat domain 28 3 15667236-15859771 Predicted intracellular proteins Evidence at protein level Renal cancer:2.85e-4 (favourable) Expressed in all Expressed in all epididymis: 35.7 ANKRD39 MGC41816 ENSG00000213337 Ankyrin repeat domain 39 2 96836611-96858095 Predicted intracellular proteins Evidence at protein level HPA042678 Approved Approved Nucleoplasm
Vesicles Renal cancer:6.78e-9 (unfavourable), Pancreatic cancer:6.12e-5 (favourable), Colorectal cancer:2.26e-4 (unfavourable), Urothelial cancer:5.21e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 17.2 ANKRD40 MGC15396 ENSG00000154945 Ankyrin repeat domain 40 17 50693190-50707924 Predicted intracellular proteins Evidence at protein level HPA021668, HPA021759 Approved Approved Golgi apparatus
Cytosol Liver cancer:7.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 58.3 ANKRD46 ENSG00000186106 Ankyrin repeat domain 46 8 100509752-100559784 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013758 Approved Approved Cytosol Expressed in all Expressed in all cerebral cortex: 70.6 ANKRD49 FGIF, FLJ20189, GBIF ENSG00000168876 Ankyrin repeat domain 49 11 94493629-94499583 Predicted intracellular proteins Evidence at protein level HPA040273, HPA048137 Approved Approved Nucleus
Nucleoli
Golgi apparatus Urothelial cancer:6.16e-4 (favourable), Renal cancer:9.96e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.2 ANKRD52 FLJ34236, PP6-ARS-C ENSG00000139645 Ankyrin repeat domain 52 12 56237807-56258391 Predicted intracellular proteins Evidence at protein level HPA043815 Uncertain Approved Nucleoplasm
Mitochondria Liver cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.5 ANKRD54 LIAR ENSG00000100124 Ankyrin repeat domain 54 22 37830855-37849327 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA071287 Approved Approved Nucleoplasm
Microtubules
Midbody Endometrial cancer:7.38e-5 (favourable), Cervical cancer:2.06e-4 (favourable), Pancreatic cancer:6.16e-4 (favourable) Expressed in all Expressed in all fallopian tube: 35.2 ANKRD9 ENSG00000156381 Ankyrin repeat domain 9 14 102501760-102509799 Predicted intracellular proteins Evidence at protein level HPA055985 Uncertain Renal cancer:1.17e-7 (favourable) Expressed in all Expressed in all duodenum: 51.8 ANKS1A ANKS1, KIAA0229 ENSG00000064999 Ankyrin repeat and sterile alpha motif domain containing 1A 6 34889265-35091413 Predicted intracellular proteins Evidence at protein level HPA036768, HPA036769 Approved Approved Nucleoplasm
Cytosol Renal cancer:8.05e-5 (favourable), Head and neck cancer:7.48e-4 (favourable) Expressed in all Expressed in all placenta: 38.9 ANKZF1 FLJ10415, ZNF744 ENSG00000163516 Ankyrin repeat and zinc finger domain containing 1 2 219229757-219236669 Predicted intracellular proteins Evidence at protein level HPA035208 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.01e-6 (unfavourable), Liver cancer:3.09e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 16.8 ANO10 FLJ10375, MGC47890, SCAR10, TMEM16K ENSG00000160746 Anoctamin 10 3 43354859-43691594 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051569 Approved Renal cancer:6.41e-6 (favourable), Endometrial cancer:1.11e-4 (favourable), Liver cancer:3.19e-4 (unfavourable), Colorectal cancer:6.70e-4 (favourable) Expressed in all Expressed in all duodenum: 64.3 ANO6 DKFZp313M0720, TMEM16F ENSG00000177119 Anoctamin 6 12 45215987-45440404 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038958 Approved Approved Plasma membrane
Cytosol Breast cancer:7.56e-5 (unfavourable), Cervical cancer:3.82e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 90.8 ANP32A C15orf1, I1PP2A, LANP, MAPM, mapmodulin, PHAPI, PP32 ENSG00000140350 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 15 68778535-68820897 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005231, HPA063133, HPA067561 Supported Approved Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all lymph node: 183.8 ANP32B APRIL, PHAPI2, SSP29 ENSG00000136938 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 9 97983361-98015943 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063133, HPA067561 Supported Approved Nucleoplasm
Centrosome
Cytosol Liver cancer:1.98e-7 (unfavourable) Expressed in all Expressed in all lymph node: 267.6 ANP32E LANP-L, LANPL, MGC5350 ENSG00000143401 Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 1 150218417-150236156 Predicted intracellular proteins Evidence at protein level CAB021114, HPA063133, HPA067561 Supported Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:3.82e-8 (unfavourable), Liver cancer:4.50e-5 (unfavourable) Expressed in all Expressed in all lymph node: 85.2 ANXA11 ANX11 ENSG00000122359 Annexin A11 10 80150889-80205572 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004851, HPA027545 Supported Supported Nucleoplasm
Cytosol Renal cancer:6.69e-8 (favourable) Expressed in all Expressed in all esophagus: 203.9 ANXA2 ANX2, ANX2L4, CAL1H, LIP2, LPC2D ENSG00000182718 Annexin A2 15 60347134-60402883 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004311 Approved Renal cancer:2.11e-6 (unfavourable), Pancreatic cancer:8.47e-6 (unfavourable), Liver cancer:2.54e-5 (unfavourable), Urothelial cancer:6.59e-5 (unfavourable), Endometrial cancer:6.88e-5 (favourable), Lung cancer:7.51e-4 (unfavourable) Expressed in all Expressed in all esophagus: 1494.3 ANXA3 ANX3 ENSG00000138772 Annexin A3 4 78551519-78610451 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013398, HPA013431 Supported Supported Cytosol Renal cancer:8.48e-6 (favourable), Pancreatic cancer:1.28e-4 (unfavourable) Mixed Expressed in all bone marrow: 198.6 ANXA4 ANX4 ENSG00000196975 Annexin A4 2 69644425-69827100 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB005076, HPA007393, CAB017560 Approved Approved Cytosol Ovarian cancer:2.38e-4 (unfavourable), Renal cancer:6.05e-4 (unfavourable), Breast cancer:8.55e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 884.9 ANXA5 ANX5, ENX2 ENSG00000164111 Annexin A5 4 121667955-121697113 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003677, HPA035330 Approved Approved Nuclear membrane Renal cancer:9.29e-7 (unfavourable), Liver cancer:1.64e-5 (unfavourable), Head and neck cancer:3.01e-5 (unfavourable), Urothelial cancer:1.26e-4 (unfavourable), Endometrial cancer:3.64e-4 (favourable), Stomach cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all placenta: 612.8 ANXA6 ANX6 ENSG00000197043 Annexin A6 5 151100712-151157882 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA002462, CAB005077, HPA009650 Supported Approved Nuclear speckles Renal cancer:1.31e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 426.1 ANXA7 ANX7 ENSG00000138279 Annexin A7 10 73375101-73414076 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004312, HPA064290 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.98e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 464.4 ANXA9 ANX31 ENSG00000143412 Annexin A9 1 150982017-150995634 Predicted intracellular proteins Evidence at protein level HPA028404, HPA028698 Supported Approved Nuclear speckles
Cytosol Renal cancer:8.74e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 46.5 AP000769.1 ENSG00000279576 Metastasis-associated lung adenocarcinoma transcript 1 11 65502034-65503622 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all thyroid gland: 482.6 AP003419.11 ENSG00000256514 11 67351572-67373584 Predicted intracellular proteins Evidence at transcript level HPA071529 Uncertain Nucleus
Nucleoli
Mitochondria
Cytosol Not detected Expressed in all tonsil: 105.1 AP1AR 2C18, C4orf16, gamma-BAR, PRO0971 ENSG00000138660 Adaptor-related protein complex 1 associated regulatory protein 4 112231737-112270047 Predicted intracellular proteins Evidence at protein level HPA035863, HPA058115 Approved Supported Golgi apparatus Renal cancer:4.05e-7 (favourable), Urothelial cancer:7.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.9 AP1B1 ADTB1, AP105A, BAM22, CLAPB2 ENSG00000100280 Adaptor-related protein complex 1, beta 1 subunit 22 29327680-29423179 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065226, HPA068520 Approved Supported Golgi apparatus
Vesicles Renal cancer:7.24e-6 (favourable), Liver cancer:5.55e-5 (unfavourable), Cervical cancer:4.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 102.2 AP1G1 ADTG, CLAPG1 ENSG00000166747 Adaptor-related protein complex 1, gamma 1 subunit 16 71729000-71809201 Predicted intracellular proteins Evidence at protein level CAB009049, HPA041224 Approved Validated Vesicles
Cytosol Renal cancer:2.96e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 87.2 AP1M1 AP47, CLAPM2 ENSG00000072958 Adaptor-related protein complex 1, mu 1 subunit 19 16197578-16245907 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045256 Uncertain Renal cancer:1.75e-4 (unfavourable) Expressed in all Expressed in all testis: 96.4 AP1S1 AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2 ENSG00000106367 Adaptor-related protein complex 1, sigma 1 subunit 7 101154397-101161596 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060945 Supported Supported Golgi apparatus
Vesicles Expressed in all Expressed in all cerebral cortex: 107.3 AP2A1 ADTAA, CLAPA1 ENSG00000196961 Adaptor-related protein complex 2, alpha 1 subunit 19 49766968-49807113 Predicted intracellular proteins Evidence at protein level CAB004306 Approved Supported Vesicles Renal cancer:2.83e-9 (unfavourable), Ovarian cancer:2.91e-4 (unfavourable) Expressed in all Expressed in all testis: 104.1 AP2B1 ADTB2, CLAPB1 ENSG00000006125 Adaptor-related protein complex 2, beta 1 subunit 17 35578046-35726409 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB017631, HPA056733 Approved Supported Vesicles Renal cancer:2.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 260.8 AP2M1 AP50, CLAPM1, mu2 ENSG00000161203 Adaptor-related protein complex 2, mu 1 subunit 3 184174689-184184091 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036849, HPA069870 Uncertain Supported Plasma membrane Renal cancer:7.45e-6 (unfavourable), Liver cancer:9.12e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 559.2 AP2S1 CLAPS2, FBH3, FBHOk, HHC3 ENSG00000042753 Adaptor-related protein complex 2, sigma 1 subunit 19 46838136-46850992 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:1.48e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 114.8 AP3B1 ADTB3A, HPS2 ENSG00000132842 Adaptor-related protein complex 3, beta 1 subunit 5 78000525-78294755 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038737, HPA045458 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:7.97e-6 (favourable), Colorectal cancer:1.37e-5 (favourable) Expressed in all Expressed in all epididymis: 64.4 AP3D1 ADTD ENSG00000065000 Adaptor-related protein complex 3, delta 1 subunit 19 2100988-2164465 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA074408 Approved Cytosol Renal cancer:2.61e-6 (favourable), Liver cancer:9.23e-4 (unfavourable) Expressed in all Expressed in all testis: 60.8 AP3M1 ENSG00000185009 Adaptor-related protein complex 3, mu 1 subunit 10 74120255-74151063 Predicted intracellular proteins Evidence at protein level HPA045591, HPA048380 Uncertain Expressed in all Expressed in all placenta: 45.6 AP3M2 AP47B, CLA20 ENSG00000070718 Adaptor-related protein complex 3, mu 2 subunit 8 42152946-42171673 Predicted intracellular proteins Evidence at protein level CAB014876, HPA045591, HPA048380 Approved Urothelial cancer:2.38e-4 (favourable), Endometrial cancer:3.46e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 47.0 AP3S1 CLAPS3 ENSG00000177879 Adaptor-related protein complex 3, sigma 1 subunit 5 115841481-115914081 Predicted intracellular proteins Evidence at protein level HPA049270 Uncertain Approved Vesicles Renal cancer:9.57e-8 (unfavourable), Pancreatic cancer:1.13e-5 (unfavourable), Breast cancer:1.22e-4 (unfavourable), Glioma:5.30e-4 (unfavourable) Expressed in all Expressed in all epididymis: 39.1 AP3S2 sigma3b ENSG00000157823 Adaptor-related protein complex 3, sigma 2 subunit 15 89830599-89894638 Predicted intracellular proteins Evidence at transcript level HPA049270 Uncertain Approved Vesicles Renal cancer:5.55e-16 (favourable) Expressed in all Expressed in all parathyroid gland: 76.2 AP4B1 BETA-4, SPG47 ENSG00000134262 Adaptor-related protein complex 4, beta 1 subunit 1 113894748-113905201 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028162, HPA028652 Approved Approved Vesicles Liver cancer:8.60e-7 (unfavourable), Renal cancer:3.73e-6 (unfavourable) Expressed in all Expressed in all spleen: 19.5 AP4M1 MU-4, MU-ARP2, SPG50 ENSG00000221838 Adaptor-related protein complex 4, mu 1 subunit 7 100101549-100110345 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA066774 Approved Liver cancer:7.63e-5 (unfavourable), Renal cancer:8.29e-4 (unfavourable) Expressed in all Expressed in all testis: 28.9 AP4S1 AP47B, CLA20, SPG52 ENSG00000100478 Adaptor-related protein complex 4, sigma 1 subunit 14 31025106-31096450 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039963 Approved Renal cancer:2.87e-6 (favourable), Lung cancer:7.44e-4 (favourable) Expressed in all Expressed in all testis: 33.2 AP5B1 AP-5, DKFZp761E198, PP1030 ENSG00000254470 Adaptor-related protein complex 5, beta 1 subunit 11 65775893-65780802 Predicted intracellular proteins Evidence at protein level HPA065739, HPA067880 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Renal cancer:2.31e-5 (favourable) Expressed in all Expressed in all bone marrow: 25.1 AP5M1 C14orf108, FLJ10813, mu5, MuD, MUDENG ENSG00000053770 Adaptor-related protein complex 5, mu 1 subunit 14 57268909-57298742 Predicted intracellular proteins Evidence at protein level HPA055768, HPA057098 Approved Renal cancer:1.11e-14 (favourable), Colorectal cancer:7.91e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 42.3 AP5S1 C20orf29, FLJ11168 ENSG00000125843 Adaptor-related protein complex 5, sigma 1 subunit 20 3820524-3828837 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB034200, HPA048244 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:5.53e-5 (favourable) Expressed in all Expressed in all testis: 12.5 APBB1 Fe65, RIR ENSG00000166313 Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 11 6395124-6419414 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022104, HPA038521, HPA038522 Approved Validated Plasma membrane Renal cancer:7.44e-13 (favourable), Pancreatic cancer:1.86e-5 (favourable), Liver cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 237.2 APBB2 FE65L, FE65L1, MGC35575 ENSG00000163697 Amyloid beta (A4) precursor protein-binding, family B, member 2 4 40810027-41216714 Predicted intracellular proteins Evidence at protein level HPA023542 Uncertain Approved Mitochondria Endometrial cancer:1.97e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.3 APEH D3F15S2, D3S48E, DNF15S2 ENSG00000164062 Acylaminoacyl-peptide hydrolase 3 49674002-49683963 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029700, HPA029701, HPA029702, HPA029703 Supported Validated Cytosol Renal cancer:3.32e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 99.6 APEX1 APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1 ENSG00000100823 APEX nuclease (multifunctional DNA repair enzyme) 1 14 20455191-20457772 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000956, HPA002564, CAB004294, CAB047307 Supported Validated Nucleus Liver cancer:7.82e-5 (unfavourable) Expressed in all Expressed in all ovary: 176.0 APEX2 APE2, APEXL2, XTH2, ZGRF2 ENSG00000169188 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 X 55000357-55009057 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048577 Supported Nucleus
Nucleoli fibrillar center
Vesicles Liver cancer:6.13e-7 (unfavourable), Ovarian cancer:5.21e-4 (favourable), Cervical cancer:6.17e-4 (favourable), Urothelial cancer:6.63e-4 (favourable) Expressed in all Expressed in all skin: 14.3 APH1A APH-1A, CGI-78 ENSG00000117362 APH1A gamma secretase subunit 1 150265399-150269580 Predicted membrane proteins Evidence at protein level CAB037272 Approved Expressed in all Expressed in all thyroid gland: 160.6 API5 AAC-11, AAC11, API5L1 ENSG00000166181 Apoptosis inhibitor 5 11 43311963-43344529 Predicted intracellular proteins Evidence at protein level HPA026598 Approved Validated Nuclear speckles Renal cancer:1.06e-4 (favourable) Expressed in all Expressed in all thyroid gland: 95.4 APIP APIP2, CGI-29, Mmrp19 ENSG00000149089 APAF1 interacting protein 11 34853094-34916499 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021188, HPA024131 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.99e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 33.0 APITD1 CENP-S, CENPS, FAAP16, MHF1 ENSG00000175279 Apoptosis-inducing, TAF9-like domain 1 1 10430443-10442809 Predicted intracellular proteins Evidence at protein level Cervical cancer:1.24e-4 (favourable) Expressed in all Expressed in all testis: 84.0 APLP2 APPH, APPL2 ENSG00000084234 Amyloid beta (A4) precursor-like protein 2 11 130069837-130144811 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039319 Approved Approved Vesicles Renal cancer:1.33e-9 (favourable), Thyroid cancer:2.90e-4 (favourable), Liver cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 1052.3 APMAP BSCv, C20orf3 ENSG00000101474 Adipocyte plasma membrane associated protein 20 24962925-24992979 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012863, HPA064700 Uncertain Approved Plasma membrane Expressed in all Expressed in all thyroid gland: 322.5 APOA1BP AIBP, MGC119143, MGC119144, MGC119145, YJEFN1 ENSG00000163382 Apolipoprotein A-I binding protein 1 156591762-156594299 Enzymes, Predicted secreted proteins Evidence at protein level HPA043766, HPA048164 Approved Validated Nucleoplasm
Cytosol Endometrial cancer:4.94e-4 (unfavourable) Expressed in all Expressed in all epididymis: 110.4 APOE AD2 ENSG00000130203 Apolipoprotein E 19 44905754-44909393 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB008363, HPA065539, HPA068768, CAB069921 Supported Approved Vesicles Expressed in all Expressed in all adrenal gland: 1810.4 APOL1 APOL ENSG00000100342 Apolipoprotein L, 1 22 36253010-36267530 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018885, CAB056156 Supported Renal cancer:7.43e-6 (unfavourable), Urothelial cancer:2.01e-5 (favourable), Lung cancer:5.35e-4 (unfavourable) Expressed in all Expressed in all liver: 116.0 APOL2 APOL-II ENSG00000128335 Apolipoprotein L, 2 22 36226203-36239954 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001078 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.22e-7 (unfavourable), Urothelial cancer:5.06e-6 (favourable) Expressed in all Expressed in all gallbladder: 65.0 APOO FAM121B, MGC4825, Mic23, MIC26, My025 ENSG00000184831 Apolipoprotein O X 23833353-23907934 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003187 Supported Approved Mitochondria
Cytosol Renal cancer:2.56e-6 (favourable), Cervical cancer:3.77e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.9 APOOL AAIR8193, CXorf33, FAM121A, Mic27, UNQ8193 ENSG00000155008 Apolipoprotein O-like X 85003826-85093316 Predicted secreted proteins Evidence at protein level HPA000612 Approved Approved Mitochondria Renal cancer:1.35e-12 (favourable), Breast cancer:2.68e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.8 APOPT1 APOP-1, C14orf153, MGC2562 ENSG00000256053 Apoptogenic 1, mitochondrial 14 103562962-103607523 Predicted intracellular proteins Evidence at transcript level Liver cancer:6.34e-5 (unfavourable), Ovarian cancer:4.78e-4 (favourable) Expressed in all Expressed in all testis: 89.3 APP AD1 ENSG00000142192 Amyloid beta (A4) precursor protein 21 25880550-26171128 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB000157, HPA001462 Supported Approved Golgi apparatus
Vesicles Renal cancer:2.79e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 1206.8 APPBP2 Hs.84084, KIAA0228, PAT1 ENSG00000062725 Amyloid beta precursor protein (cytoplasmic tail) binding protein 2 17 60443149-60526219 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA050874 Supported Cytosol Liver cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all testis: 44.5 APPL1 APPL ENSG00000157500 Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 3 57227737-57273468 Predicted intracellular proteins Evidence at protein level HPA011138, HPA073477 Approved Uncertain Mitotic spindle
Centrosome Renal cancer:7.26e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 43.5 APPL2 DIP13B, FLJ10659 ENSG00000136044 Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 12 105173296-105236238 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039688, HPA043925 Approved Renal cancer:7.65e-4 (favourable) Expressed in all Expressed in all skin: 78.1 APRT ENSG00000198931 Adenine phosphoribosyltransferase 16 88809339-88811944 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026681 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all skin: 112.4 APTX AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157 ENSG00000137074 Aprataxin 9 32972606-33025168 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064930 Supported Validated Nucleus
Nucleoli Renal cancer:6.01e-5 (favourable) Expressed in all Expressed in all testis: 24.3 AQP1 CHIP28, CO ENSG00000240583 Aquaporin 1 (Colton blood group) 7 30911855-30925516 Blood group antigen proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB001707, HPA019206 Supported Supported Plasma membrane Renal cancer:1.32e-8 (favourable), Head and neck cancer:6.52e-4 (favourable) Expressed in all Expressed in all kidney: 801.2 AQP3 GIL ENSG00000165272 Aquaporin 3 (Gill blood group) 9 33441154-33447611 Blood group antigen proteins, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA014924 Supported Supported Nucleus
Plasma membrane Cervical cancer:5.31e-4 (favourable) Expressed in all Expressed in all esophagus: 975.2 ARAF ARAF1 ENSG00000078061 A-Raf proto-oncogene, serine/threonine kinase X 47561100-47571920 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046188, HPA066326 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.45e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 84.7 ARAP1 CENTD2 ENSG00000186635 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 11 72685069-72793599 Predicted intracellular proteins Evidence at protein level CAB020703, HPA070383 Approved Approved Nucleoplasm
Vesicles
Plasma membrane
Cytosol Pancreatic cancer:2.04e-5 (favourable), Thyroid cancer:6.41e-4 (favourable), Liver cancer:6.45e-4 (unfavourable) Expressed in all Expressed in all spleen: 92.9 ARCN1 COPD ENSG00000095139 Archain 1 11 118572390-118603033 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037573, HPA044874 Approved Validated Golgi apparatus
Vesicles Liver cancer:2.97e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 142.0 AREL1 KIAA0317 ENSG00000119682 Apoptosis resistant E3 ubiquitin protein ligase 1 14 74653437-74713115 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051306 Uncertain Renal cancer:4.67e-6 (favourable) Expressed in all Expressed in all testis: 33.7 ARF1 ENSG00000143761 ADP-ribosylation factor 1 1 228082660-228099212 Predicted intracellular proteins Evidence at protein level CAB007742 Uncertain Approved Plasma membrane
Cytosol Head and neck cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all placenta: 381.7 ARF3 ENSG00000134287 ADP-ribosylation factor 3 12 48935723-48957551 Plasma proteins, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 403.8 ARF4 ARF2 ENSG00000168374 ADP-ribosylation factor 4 3 57571363-57598220 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:7.29e-7 (unfavourable), Thyroid cancer:9.30e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 325.0 ARF5 ENSG00000004059 ADP-ribosylation factor 5 7 127588345-127591705 Plasma proteins, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all skin: 176.5 ARF6 ENSG00000165527 ADP-ribosylation factor 6 14 49893092-49897054 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002778 Approved Pancreatic cancer:3.10e-5 (unfavourable) Expressed in all Expressed in all esophagus: 96.9 ARFGAP1 ARF1GAP, bA261N11.3, FLJ10767 ENSG00000101199 ADP-ribosylation factor GTPase activating protein 1 20 63272785-63289793 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051019, HPA056273 Approved Supported Nuclear membrane
Golgi apparatus
Vesicles Renal cancer:3.48e-7 (unfavourable), Pancreatic cancer:4.57e-4 (favourable) Expressed in all Expressed in all testis: 32.2 ARFGAP2 FLJ14576, IRZ, Zfp289, ZNF289 ENSG00000149182 ADP-ribosylation factor GTPase activating protein 2 11 47164299-47177125 Predicted intracellular proteins Evidence at protein level HPA016649, HPA018152 Supported Supported Golgi apparatus Renal cancer:7.65e-7 (favourable) Expressed in all Expressed in all skin: 90.2 ARFGAP3 ARFGAP1 ENSG00000242247 ADP-ribosylation factor GTPase activating protein 3 22 42796502-42858106 Predicted intracellular proteins Evidence at protein level HPA000638 Approved Supported Golgi apparatus
Cytosol Endometrial cancer:8.97e-6 (favourable), Thyroid cancer:2.65e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 113.0 ARFGEF1 ARFGEP1, BIG1, DKFZP434L057, p200 ENSG00000066777 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 8 67173511-67343677 Predicted intracellular proteins Evidence at protein level HPA023399, HPA023822 Supported Approved Validated Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:2.48e-4 (favourable), Breast cancer:8.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.6 ARFGEF2 BIG2 ENSG00000124198 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 20 48921890-49036693 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026078, CAB026382 Supported Supported Golgi apparatus Renal cancer:6.15e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 171.2 ARFIP1 HSU52521 ENSG00000164144 ADP-ribosylation factor interacting protein 1 4 152687727-152918463 Predicted intracellular proteins Evidence at protein level CAB005080, HPA037375, HPA063759 Supported Supported Nucleus
Golgi apparatus
Vesicles Renal cancer:2.83e-10 (favourable), Colorectal cancer:5.75e-5 (favourable) Expressed in all Expressed in all endometrium: 39.0 ARFIP2 POR1 ENSG00000132254 ADP-ribosylation factor interacting protein 2 11 6474683-6481479 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB032985, HPA038156 Approved Approved Nucleus
Nucleoli fibrillar center
Golgi apparatus Endometrial cancer:2.00e-5 (favourable), Renal cancer:9.53e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 81.1 ARFRP1 ARL18, ARP, Arp1 ENSG00000101246 ADP-ribosylation factor related protein 1 20 63698642-63708025 Predicted intracellular proteins Evidence at protein level HPA047028, HPA050634 Approved Supported Golgi apparatus Expressed in all Expressed in all spleen: 28.4 ARGLU1 FLJ10154 ENSG00000134884 Arginine and glutamate rich 1 13 106541673-106568164 Predicted intracellular proteins Evidence at protein level HPA034962, HPA056792 Supported Validated Nucleoplasm
Mitochondria Pancreatic cancer:3.92e-5 (favourable), Urothelial cancer:7.34e-5 (favourable), Renal cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all endometrium: 328.7 ARHGAP1 CDC42GAP, p50rhoGAP, RhoGAP ENSG00000175220 Rho GTPase activating protein 1 11 46677080-46700615 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004689, HPA008285 Approved Approved Supported Vesicles Liver cancer:2.14e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 114.7 ARHGAP10 FLJ20896, FLJ41791, GRAF2 ENSG00000071205 Rho GTPase activating protein 10 4 147732063-148072780 Predicted intracellular proteins Evidence at protein level HPA039589 Approved Nucleoplasm
Nuclear membrane
Cytosol Renal cancer:8.15e-5 (favourable), Lung cancer:2.23e-4 (unfavourable), Stomach cancer:6.26e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 43.4 ARHGAP12 FLJ10971, FLJ20737, FLJ21785 ENSG00000165322 Rho GTPase activating protein 12 10 31805404-31928876 Predicted intracellular proteins Evidence at protein level HPA000412 Approved Renal cancer:4.64e-5 (favourable), Glioma:1.88e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 44.4 ARHGAP17 FLJ10308, FLJ13219, NADRIN, RICH1, WBP15 ENSG00000140750 Rho GTPase activating protein 17 16 24919385-25015666 Predicted intracellular proteins Evidence at protein level HPA041703 Approved Approved Nucleus
Cytosol Endometrial cancer:3.59e-4 (favourable), Urothelial cancer:3.76e-4 (unfavourable), Liver cancer:4.95e-4 (unfavourable) Expressed in all Expressed in all spleen: 71.6 ARHGAP18 bA307O14.2, MacGAP ENSG00000146376 Rho GTPase activating protein 18 6 129576132-129710225 Predicted intracellular proteins Evidence at protein level HPA031595 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Pancreatic cancer:2.54e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 48.2 ARHGAP21 ARHGAP10, KIAA1424 ENSG00000107863 Rho GTPase activating protein 21 10 24583609-24723668 Predicted intracellular proteins Evidence at protein level HPA036610, HPA057861 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Expressed in all Expressed in all cerebral cortex: 103.8 ARHGAP24 DKFZP564B1162, FilGAP, FLJ33877 ENSG00000138639 Rho GTPase activating protein 24 4 85475114-86002670 Predicted intracellular proteins Evidence at protein level HPA014288 Approved Approved Plasma membrane
Cytosol Renal cancer:1.67e-11 (favourable) Expressed in all Expressed in all kidney: 105.5 ARHGAP32 GC-GAP, GRIT, KIAA0712, MGC1892, RICS ENSG00000134909 Rho GTPase activating protein 32 11 128965060-129279324 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038382, HPA038389, HPA061505 Approved Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Pancreatic cancer:6.64e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 44.2 ARHGAP35 GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP ENSG00000160007 Rho GTPase activating protein 35 19 46918676-47005077 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB037311, HPA055184, HPA056470 Approved Supported Nuclear bodies
Aggresome Renal cancer:5.55e-8 (favourable) Expressed in all Expressed in all testis: 96.5 ARHGAP5 GFI2, p190-B, p190BRhoGAP, RhoGAP5 ENSG00000100852 Rho GTPase activating protein 5 14 32076114-32159728 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046993, HPA056507 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:3.97e-8 (favourable) Expressed in all Expressed in all thyroid gland: 117.3 ARHGDIA GDIA1, RHOGDI ENSG00000141522 Rho GDP dissociation inhibitor (GDI) alpha 17 81867721-81871406 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010005, HPA021407 Approved Validated Cytosol Lung cancer:7.63e-4 (unfavourable) Expressed in all Expressed in all appendix: 213.0 ARHGDIB GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2 ENSG00000111348 Rho GDP dissociation inhibitor (GDI) beta 12 14942017-14961728 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018584, HPA051235 Approved Supported Cytosol Renal cancer:1.08e-4 (unfavourable), Urothelial cancer:3.42e-4 (favourable) Expressed in all Expressed in all lymph node: 968.2 ARHGEF1 LBCL2, P115-RHOGEF, SUB1.5 ENSG00000076928 Rho guanine nucleotide exchange factor (GEF) 1 19 41883161-41930150 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009502, HPA012924, HPA060784 Supported Validated Plasma membrane
Cytosol Renal cancer:3.36e-8 (unfavourable), Breast cancer:5.92e-4 (favourable) Expressed in all Expressed in all lymph node: 147.0 ARHGEF10L FLJ10521, KIAA1626 ENSG00000074964 Rho guanine nucleotide exchange factor (GEF) 10-like 1 17539835-17697874 Predicted intracellular proteins Evidence at protein level HPA026426, HPA026440, HPA028115 Approved Approved Golgi apparatus
Vesicles
Cytosol Head and neck cancer:8.13e-5 (favourable), Renal cancer:5.65e-4 (favourable) Expressed in all Expressed in all thyroid gland: 29.6 ARHGEF11 GTRAP48, KIAA0380, PDZ-RHOGEF ENSG00000132694 Rho guanine nucleotide exchange factor (GEF) 11 1 156934840-157045370 Predicted intracellular proteins Evidence at protein level HPA011026, HPA012037, HPA014658 Approved Approved Golgi apparatus
Plasma membrane Pancreatic cancer:1.72e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 43.6 ARHGEF12 KIAA0382, LARG ENSG00000196914 Rho guanine nucleotide exchange factor (GEF) 12 11 120336914-120489936 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018911, CAB025581 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:5.43e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 143.2 ARHGEF17 KIAA0337, p164-RhoGEF, TEM4 ENSG00000110237 Rho guanine nucleotide exchange factor (GEF) 17 11 73308289-73369091 Predicted intracellular proteins Evidence at protein level HPA007991 Uncertain Approved Cytosol Colorectal cancer:8.27e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.0 ARHGEF18 KIAA0521, MGC15913, P114-RhoGEF ENSG00000104880 Rho/Rac guanine nucleotide exchange factor (GEF) 18 19 7395113-7472477 Predicted intracellular proteins Evidence at protein level HPA042689, HPA071867 Approved Validated Cytosol Renal cancer:3.11e-5 (favourable), Head and neck cancer:4.21e-4 (favourable) Expressed in all Expressed in all spleen: 31.1 ARHGEF2 GEF-H1, KIAA0651, LFP40, P40 ENSG00000116584 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1 155946851-156007070 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043437 Approved Renal cancer:7.17e-6 (unfavourable), Liver cancer:9.20e-6 (unfavourable) Expressed in all Expressed in all lung: 95.3 ARHGEF3 DKFZP434F2429, GEF3, STA3, XPLN ENSG00000163947 Rho guanine nucleotide exchange factor (GEF) 3 3 56727418-57079329 Predicted intracellular proteins Evidence at protein level HPA034715, HPA064945 Uncertain Approved Cytosol Renal cancer:1.96e-7 (favourable), Endometrial cancer:2.17e-4 (favourable), Head and neck cancer:2.61e-4 (favourable) Expressed in all Expressed in all endometrium: 64.6 ARHGEF37 FLJ41603 ENSG00000183111 Rho guanine nucleotide exchange factor (GEF) 37 5 149551947-149634968 Predicted intracellular proteins Evidence at protein level HPA043885, HPA053487 Uncertain Approved Cytosol Renal cancer:6.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 67.1 ARHGEF40 FLJ10357, solo ENSG00000165801 Rho guanine nucleotide exchange factor (GEF) 40 14 21070270-21090240 Predicted intracellular proteins Evidence at protein level HPA030746, HPA030757 Uncertain Expressed in all Expressed in all adrenal gland: 32.7 ARHGEF7 BETA-PIX, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB ENSG00000102606 Rho guanine nucleotide exchange factor (GEF) 7 13 111114559-111305737 Predicted intracellular proteins Evidence at protein level HPA004744 Approved Glioma:7.29e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 97.1 ARHGEF9 KIAA0424, PEM-2 ENSG00000131089 Cdc42 guanine nucleotide exchange factor (GEF) 9 X 63634967-63809274 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035419, HPA055291 Approved Supported Cytosol Renal cancer:1.02e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 91.1 ARID1A B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1 ENSG00000117713 AT rich interactive domain 1A (SWI-like) 1 26696033-26782104 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005456, CAB016334 Supported Validated Nucleoplasm Liver cancer:4.18e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.4 ARID1B 6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R ENSG00000049618 AT rich interactive domain 1B (SWI1-like) 6 156777374-157210779 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016511, HPA075291 Approved Supported Nucleoplasm Breast cancer:1.04e-4 (unfavourable), Ovarian cancer:4.16e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.6 ARID2 BAF200, DKFZp686G052, FLJ30619, KIAA1557 ENSG00000189079 AT rich interactive domain 2 (ARID, RFX-like) 12 45729665-45908040 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063044 Supported Nucleoplasm
Plasma membrane Head and neck cancer:5.75e-4 (favourable) Expressed in all Expressed in all testis: 47.3 ARID4A RBBP1, RBP-1, RBP1 ENSG00000032219 AT rich interactive domain 4A (RBP1-like) 14 58298385-58373887 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048899 Supported Nucleoplasm
Plasma membrane
Cytosol Head and neck cancer:1.91e-4 (favourable), Lung cancer:7.82e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.1 ARID4B BCAA, BRCAA1, RBP1L1, SAP180 ENSG00000054267 AT rich interactive domain 4B (RBP1-like) 1 235131634-235328219 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027333, HPA053692 Approved Approved Nucleoplasm
Vesicles Renal cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all testis: 30.3 ARID5A MRF-1, RP11-363D14 ENSG00000196843 AT rich interactive domain 5A (MRF1-like) 2 96536743-96552638 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002860, HPA023879 Approved Supported Nucleus
Nucleoli Renal cancer:4.24e-8 (unfavourable), Breast cancer:2.05e-6 (favourable) Expressed in all Expressed in all appendix: 26.1 ARID5B FLJ21150, MRF2 ENSG00000150347 AT rich interactive domain 5B (MRF1-like) 10 61901300-62096944 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015037 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all gallbladder: 62.1 ARIH1 ARI, HARI, HHARI, UBCH7BP ENSG00000166233 Ariadne RBR E3 ubiquitin protein ligase 1 15 72474326-72602985 Predicted intracellular proteins Evidence at protein level HPA003295, HPA073245 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 65.3 ARIH2 TRIAD1 ENSG00000177479 Ariadne RBR E3 ubiquitin protein ligase 2 3 48918821-48986382 Predicted intracellular proteins Evidence at protein level HPA067381, HPA069715, HPA070963 Validated Nucleoplasm Liver cancer:1.70e-4 (unfavourable), Renal cancer:6.60e-4 (favourable), Pancreatic cancer:7.31e-4 (favourable) Expressed in all Expressed in all testis: 49.7 ARL1 ARFL1 ENSG00000120805 ADP-ribosylation factor-like 1 12 101393120-101407820 Predicted intracellular proteins Evidence at protein level HPA062656, HPA073012 Approved Supported Golgi apparatus Endometrial cancer:1.61e-4 (favourable) Expressed in all Expressed in all thyroid gland: 141.5 ARL14EP ARF7EP, C11orf46, FLJ38968 ENSG00000152219 ADP-ribosylation factor-like 14 effector protein 11 30323051-30338227 Predicted intracellular proteins Evidence at protein level HPA039634, HPA048127 Approved Approved Nucleus
Vesicles
Focal adhesion sites
Cytosol Breast cancer:2.50e-5 (favourable), Liver cancer:5.26e-4 (unfavourable), Urothelial cancer:7.49e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 52.5 ARL15 ARFRP2, FLJ20051 ENSG00000185305 ADP-ribosylation factor-like 15 5 53883945-54310582 Predicted intracellular proteins Evidence at protein level HPA044604, HPA063820 Uncertain Approved Golgi apparatus
Plasma membrane
Cell Junctions Expressed in all Expressed in all placenta: 44.4 ARL16 ENSG00000214087 ADP-ribosylation factor-like 16 17 81681174-81683924 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043711 Uncertain Expressed in all Expressed in all cerebral cortex: 37.9 ARL2 ARFL2 ENSG00000213465 ADP-ribosylation factor-like 2 11 65014113-65022184 Predicted intracellular proteins Evidence at protein level HPA044610 Supported Approved Nucleus
Nucleoli
Golgi apparatus
Focal adhesion sites
Cytosol Endometrial cancer:4.58e-4 (unfavourable), Prostate cancer:7.70e-4 (favourable) Expressed in all Expressed in all fallopian tube: 112.7 ARL2BP BART, BART1, RP66 ENSG00000102931 ADP-ribosylation factor-like 2 binding protein 16 57245098-57253635 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043066, HPA048440 Approved Lung cancer:9.06e-5 (unfavourable) Expressed in all Expressed in all testis: 95.4 ARL3 ARFL3 ENSG00000138175 ADP-ribosylation factor-like 3 10 102673731-102714407 Predicted intracellular proteins Evidence at protein level HPA036292, HPA063596 Approved Supported Nucleus
Centrosome Renal cancer:1.71e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 35.9 ARL5A ARL5 ENSG00000162980 ADP-ribosylation factor-like 5A 2 151788984-151828492 Predicted intracellular proteins Evidence at protein level HPA027002 Approved Expressed in all Expressed in all thyroid gland: 64.4 ARL6IP1 AIP1, ARL6IP, ARMER, KIAA0069, SPG61 ENSG00000170540 ADP-ribosylation factor-like 6 interacting protein 1 16 18791667-18801678 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045307 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 388.0 ARL6IP4 SFRS20, SR-25, SRp25, SRrp37 ENSG00000182196 ADP-ribosylation factor-like 6 interacting protein 4 12 122980060-122982913 Predicted intracellular proteins Evidence at protein level HPA052098 Approved Urothelial cancer:1.08e-4 (favourable) Expressed in all Expressed in all adrenal gland: 186.8 ARL6IP5 DERP11, GTRAP3-18, HSPC127, JWA, PRAF3 ENSG00000144746 ADP-ribosylation factor-like 6 interacting protein 5 3 69084944-69106066 Predicted membrane proteins Evidence at protein level HPA015540, CAB019321 Supported Approved Endoplasmic reticulum Expressed in all Expressed in all prostate: 217.5 ARL8A ARL10B, FLJ45195, Gie2 ENSG00000143862 ADP-ribosylation factor-like 8A 1 202133404-202144743 Predicted intracellular proteins Evidence at protein level HPA038759, HPA040515, HPA045924 Approved Colorectal cancer:3.08e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 113.9 ARL8B ARL10C, FLJ10702, Gie1 ENSG00000134108 ADP-ribosylation factor-like 8B 3 5122220-5180912 Predicted intracellular proteins Evidence at protein level HPA038759, HPA040515, HPA045924 Approved Liver cancer:3.68e-6 (unfavourable), Renal cancer:4.84e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 119.0 ARMC1 Arcp, FLJ10511 ENSG00000104442 Armadillo repeat containing 1 8 65602456-65634217 Predicted intracellular proteins Evidence at protein level HPA026085 Approved Supported Mitochondria Endometrial cancer:2.87e-4 (unfavourable), Breast cancer:4.81e-4 (unfavourable), Liver cancer:7.73e-4 (unfavourable), Pancreatic cancer:9.15e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 34.8 ARMC10 MGC3195, SVH ENSG00000170632 Armadillo repeat containing 10 7 103074881-103099764 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011036, HPA011057 Supported Supported Mitochondria Pancreatic cancer:2.49e-6 (unfavourable), Glioma:6.98e-6 (unfavourable), Liver cancer:3.58e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.5 ARMC6 MGC19595 ENSG00000105676 Armadillo repeat containing 6 19 19033575-19060311 Predicted intracellular proteins Evidence at protein level HPA041420, HPA041681 Supported Validated Cytosol Expressed in all Expressed in all testis: 28.8 ARMC7 FLJ22160 ENSG00000125449 Armadillo repeat containing 7 17 75109952-75130265 Predicted intracellular proteins Evidence at protein level HPA024229, HPA053076 Uncertain Supported Cytosol Liver cancer:2.24e-5 (unfavourable), Renal cancer:1.27e-4 (favourable), Cervical cancer:2.98e-4 (favourable) Expressed in all Expressed in all lung: 12.7 ARMC8 DKFZP434A043, GID5, HSPC056, VID28 ENSG00000114098 Armadillo repeat containing 8 3 138187248-138298389 Predicted intracellular proteins Evidence at protein level HPA036996, HPA044869 Approved Approved Nucleoplasm
Vesicles
Cytosol Liver cancer:8.90e-5 (unfavourable), Endometrial cancer:2.05e-4 (unfavourable), Prostate cancer:2.15e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 38.2 ARMCX1 ALEX1, GASP7 ENSG00000126947 Armadillo repeat containing, X-linked 1 X 101550531-101554700 Predicted membrane proteins Evidence at protein level HPA005685, CAB020695 Supported Approved Nucleus
Mitochondria
Cytosol Pancreatic cancer:7.32e-5 (favourable), Cervical cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all ovary: 58.9 ARMCX3 ALEX3, GASP6 ENSG00000102401 Armadillo repeat containing, X-linked 3 X 101622797-101627843 Predicted membrane proteins Evidence at protein level HPA000325, HPA000967, HPA001530 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.55e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 165.0 ARMCX5 FLJ12969, GASP5 ENSG00000125962 Armadillo repeat containing, X-linked 5 X 102599168-102604159 Predicted intracellular proteins Evidence at protein level HPA000996 Approved Approved Nuclear speckles
Cytosol Lung cancer:6.58e-5 (favourable) Expressed in all Expressed in all thyroid gland: 32.6 ARMCX6 FLJ20811, GASP10 ENSG00000198960 Armadillo repeat containing, X-linked 6 X 101615118-101618001 Predicted membrane proteins Evidence at protein level HPA043030, HPA048125 Approved Supported Nucleus
Nuclear membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 33.6 ARMT1 C6orf211, FLJ12910 ENSG00000146476 Acidic residue methyltransferase 1 6 151452258-151470101 Predicted intracellular proteins Evidence at protein level HPA003004, HPA005819 Uncertain Approved Nucleus
Nuclear bodies
Cytosol Colorectal cancer:4.14e-4 (favourable), Cervical cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 42.5 ARNT bHLHe2, HIF-1beta ENSG00000143437 Aryl hydrocarbon receptor nuclear translocator 1 150809705-150876768 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001759, CAB004318 Supported Supported Nucleus
Nuclear bodies Expressed in all Expressed in all ovary: 46.6 ARNTL bHLHe5, BMAL1, JAP3, MOP3, PASD3 ENSG00000133794 Aryl hydrocarbon receptor nuclear translocator-like 11 13276652-13387266 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB045962, HPA050938 Supported Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 27.5 ARPC1A Arc40, SOP2Hs, SOP2L ENSG00000241685 Actin related protein 2/3 complex, subunit 1A, 41kDa 7 99325898-99388164 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004334 Approved Approved Cell Junctions
Cytosol Liver cancer:4.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 131.0 ARPC1B ARC41, p40-ARC, p41-ARC ENSG00000130429 Actin related protein 2/3 complex, subunit 1B, 41kDa 7 99374249-99394801 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004832 Approved Supported Vesicles
Cytosol Renal cancer:1.62e-6 (unfavourable), Liver cancer:2.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 259.0 ARPC2 ARC34, p34-Arc ENSG00000163466 Actin related protein 2/3 complex, subunit 2, 34kDa 2 218217094-218254356 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001994, HPA008352 Approved Supported Golgi apparatus
Cytosol Renal cancer:1.07e-7 (unfavourable), Liver cancer:3.63e-5 (unfavourable) Expressed in all Expressed in all lymph node: 544.0 ARPC3 ARC21, p21-Arc ENSG00000111229 Actin related protein 2/3 complex, subunit 3, 21kDa 12 110434825-110450422 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006550 Approved Uncertain Nucleoplasm Renal cancer:2.22e-11 (unfavourable), Pancreatic cancer:4.67e-4 (unfavourable) Expressed in all Expressed in all lymph node: 616.5 ARPC4 ARC20, p20-Arc ENSG00000241553 Actin related protein 2/3 complex, subunit 4, 20kDa 3 9792495-9807726 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:1.29e-4 (unfavourable), Urothelial cancer:2.34e-4 (favourable) Expressed in all Expressed in all lymph node: 167.0 ARPC5 ARC16, dJ127C7.3, p16-Arc ENSG00000162704 Actin related protein 2/3 complex, subunit 5, 16kDa 1 183620846-183635757 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022013, HPA031972 Approved Approved Vesicles
Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.21e-10 (unfavourable), Liver cancer:3.63e-4 (unfavourable) Expressed in all Expressed in all appendix: 207.6 ARPC5L ARC16-2, MGC3038 ENSG00000136950 Actin related protein 2/3 complex, subunit 5-like 9 124862130-124877733 Predicted intracellular proteins Evidence at protein level HPA022013 Approved Expressed in all Expressed in all testis: 75.4 ARPP19 ARPP-16, ARPP-19, ARPP16, ENSAL ENSG00000128989 CAMP-regulated phosphoprotein, 19kDa 15 52547045-52569883 Predicted intracellular proteins Evidence at protein level HPA056851 Approved Renal cancer:1.72e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 512.0 ARRB1 ARR1 ENSG00000137486 Arrestin, beta 1 11 75264182-75351705 Predicted intracellular proteins Evidence at protein level CAB003763, HPA049318 Approved Supported Nucleoplasm Expressed in all Expressed in all lung: 80.5 ARRB2 ARR2, BARR2, DKFZp686L0365 ENSG00000141480 Arrestin, beta 2 17 4710489-4721499 Predicted intracellular proteins Evidence at protein level HPA065681 Supported Vesicles Prostate cancer:2.61e-5 (unfavourable), Cervical cancer:2.93e-5 (favourable) Expressed in all Expressed in all bone marrow: 171.8 ARRDC1 MGC40555 ENSG00000197070 Arrestin domain containing 1 9 137605654-137615360 Predicted intracellular proteins Evidence at protein level HPA022915, HPA044345 Uncertain Approved Nucleus
Nucleoli Renal cancer:3.59e-4 (favourable) Expressed in all Expressed in all stomach: 26.5 ARRDC2 CLONE24945, PP2703 ENSG00000105643 Arrestin domain containing 2 19 18001132-18014102 Predicted intracellular proteins Evidence at transcript level HPA053788 Uncertain Approved Nucleoplasm
Cytosol Urothelial cancer:2.92e-4 (favourable), Ovarian cancer:5.84e-4 (unfavourable), Cervical cancer:5.93e-4 (favourable), Thyroid cancer:6.91e-4 (favourable) Expressed in all Expressed in all bone marrow: 51.1 ARRDC3 KIAA1376 ENSG00000113369 Arrestin domain containing 3 5 91368724-91383359 Predicted intracellular proteins Evidence at protein level Renal cancer:4.25e-8 (unfavourable), Stomach cancer:2.26e-4 (unfavourable), Ovarian cancer:3.30e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 142.5 ARRDC4 FLJ36045 ENSG00000140450 Arrestin domain containing 4 15 97960698-97973838 Predicted intracellular proteins Evidence at protein level HPA042109 Approved Expressed in all Expressed in all skin: 42.1 ARSA ENSG00000100299 Arylsulfatase A 22 50622754-50628173 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005554, CAB025183 Supported Uncertain Golgi apparatus
Cytosol Endometrial cancer:2.96e-5 (favourable) Expressed in all Expressed in all testis: 37.4 ARV1 ENSG00000173409 ARV1 homolog, fatty acid homeostasis modulator 1 230978981-231000595 Predicted membrane proteins, Transporters Evidence at protein level HPA035709 Approved Approved Vesicles Lung cancer:3.27e-5 (favourable), Colorectal cancer:1.33e-4 (favourable) Expressed in all Expressed in all testis: 61.6 ASAH1 AC, ASAH, FLJ21558, PHP32 ENSG00000104763 N-acylsphingosine amidohydrolase (acid ceramidase) 1 8 18056425-18084985 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005468 Supported Renal cancer:3.08e-8 (favourable) Expressed in all Expressed in all thyroid gland: 698.9 ASAP1 CENTB4, DDEF1, KIAA1249, PAP, ZG14P ENSG00000153317 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 8 130052104-130443660 Predicted intracellular proteins Evidence at protein level HPA011136, CAB037292, HPA048565 Approved Approved Plasma membrane
Centrosome
Cytosol Liver cancer:5.63e-8 (unfavourable), Renal cancer:1.50e-7 (unfavourable), Lung cancer:3.56e-5 (unfavourable), Endometrial cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all testis: 56.0 ASB13 FLJ13134, MGC19879 ENSG00000196372 Ankyrin repeat and SOCS box containing 13 10 5638867-5666595 Predicted intracellular proteins Evidence at protein level HPA048293, HPA061742 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all small intestine: 28.5 ASB3 ASB-3 ENSG00000115239 Ankyrin repeat and SOCS box containing 3 2 53532672-53787610 Predicted intracellular proteins Evidence at protein level HPA003940 Uncertain Mixed Expressed in all cerebral cortex: 28.3 ASB6 ENSG00000148331 Ankyrin repeat and SOCS box containing 6 9 129634604-129642169 Predicted intracellular proteins Evidence at protein level HPA004341 Approved Colorectal cancer:1.06e-5 (unfavourable), Liver cancer:2.40e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 22.8 ASB8 FLJ21255, MGC5540 ENSG00000177981 Ankyrin repeat and SOCS box containing 8 12 48147788-48181213 Predicted intracellular proteins Evidence at protein level HPA003299 Approved Renal cancer:6.57e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 98.2 ASCC1 ASC1p50, CGI-18, Em:AC022392.3 ENSG00000138303 Activating signal cointegrator 1 complex subunit 1 10 72096032-72217134 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038038, HPA057567 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:2.00e-4 (unfavourable), Liver cancer:3.52e-4 (unfavourable) Expressed in all Expressed in all testis: 46.1 ASCC2 ASC1p100, DKFZp586O0223, FLJ21588 ENSG00000100325 Activating signal cointegrator 1 complex subunit 2 22 29788608-29838304 Predicted intracellular proteins Evidence at protein level HPA001439 Uncertain Approved Nucleus
Focal adhesion sites
Cytosol Expressed in all Expressed in all testis: 45.9 ASCC3 ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH ENSG00000112249 Activating signal cointegrator 1 complex subunit 3 6 100508194-100881372 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031608, HPA031609, HPA031610 Approved Supported Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 26.0 ASF1A CIA, DKFZP547E2110 ENSG00000111875 Anti-silencing function 1A histone chaperone 6 118894220-118909167 Predicted intracellular proteins Evidence at protein level HPA030502, HPA071495 Validated Nucleus Liver cancer:5.02e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.1 ASH1L ASH1, ASH1L1, huASH1, KMT2H ENSG00000116539 Ash1 (absent, small, or homeotic)-like (Drosophila) 1 155335268-155562807 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004806 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:3.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 37.3 ASH2L ASH2, ASH2L1, ASH2L2, Bre2 ENSG00000129691 Ash2 (absent, small, or homeotic)-like (Drosophila) 8 38105242-38144076 Predicted intracellular proteins Evidence at protein level HPA042289 Approved Supported Nucleoplasm
Plasma membrane Renal cancer:4.25e-4 (favourable) Expressed in all Expressed in all testis: 74.5 ASL ENSG00000126522 Argininosuccinate lyase 7 66075798-66093558 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003696, HPA016646 Supported Approved Cytosol Cervical cancer:4.05e-6 (unfavourable) Expressed in all Expressed in all liver: 97.4 ASMTL ENSG00000169093 Acetylserotonin O-methyltransferase-like X 1403139-1453762 Predicted intracellular proteins Evidence at protein level HPA003630, HPA021865 Supported Validated Cytosol Expressed in all Expressed in all seminal vesicle: 36.1 ASNA1 ARSA-I, GET3, TRC40 ENSG00000198356 ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 19 12737139-12748323 Predicted intracellular proteins, Transporters Evidence at protein level HPA045951, HPA048087 Approved Validated Nucleus
Nucleoli Renal cancer:4.27e-5 (favourable), Urothelial cancer:8.47e-4 (unfavourable), Cervical cancer:9.53e-4 (favourable) Expressed in all Expressed in all thyroid gland: 93.7 ASNS ENSG00000070669 Asparagine synthetase (glutamine-hydrolyzing) 7 97852118-97872542 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004924, HPA029318, HPA064737 Approved Validated Cytosol Renal cancer:6.21e-7 (unfavourable), Liver cancer:9.42e-6 (unfavourable), Head and neck cancer:8.79e-5 (unfavourable), Endometrial cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 74.3 ASNSD1 FLJ20752, NBLA00058, NS3TP1 ENSG00000138381 Asparagine synthetase domain containing 1 2 189661385-189670831 Predicted intracellular proteins Evidence at protein level HPA036132, HPA036133, HPA075042 Uncertain Approved Cytosol Glioma:5.68e-4 (favourable), Liver cancer:8.66e-4 (unfavourable) Expressed in all Expressed in all placenta: 50.9 ASPH BAH, CASQ2BP1, HAAH, JCTN ENSG00000198363 Aspartate beta-hydroxylase 8 61500556-61714640 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055161, HPA059303 Uncertain Supported Endoplasmic reticulum Renal cancer:1.57e-5 (unfavourable), Cervical cancer:8.07e-5 (unfavourable), Pancreatic cancer:1.75e-4 (unfavourable), Lung cancer:3.61e-4 (unfavourable), Thyroid cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 394.0 ASPSCR1 ASPL, ASPS, UBXD9, UBXN9 ENSG00000169696 Alveolar soft part sarcoma chromosome region, candidate 1 17 81976807-82017406 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026749 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Renal cancer:1.26e-4 (unfavourable), Pancreatic cancer:2.67e-4 (favourable), Head and neck cancer:8.55e-4 (favourable) Expressed in all Expressed in all testis: 21.3 ASRGL1 ALP, ALP1, FLJ22316 ENSG00000162174 Asparaginase like 1 11 62337448-62393412 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029725, HPA055572, CAB070192 Supported Approved Nucleoplasm
Microtubules Renal cancer:4.32e-7 (favourable), Endometrial cancer:1.56e-5 (favourable), Colorectal cancer:6.14e-4 (favourable), Liver cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 180.8 ASTN2 KIAA0634 ENSG00000148219 Astrotactin 2 9 116425225-117415070 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027035 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:6.66e-16 (favourable) Expressed in all Expressed in all prostate: 42.3 ASUN C12orf11, FLJ10637, Mat89Bb, NET48, SPATA30 ENSG00000064102 Asunder spermatogenesis regulator 12 26905181-26938326 Predicted intracellular proteins Evidence at protein level HPA039543 Uncertain Liver cancer:1.17e-10 (unfavourable), Renal cancer:3.16e-6 (unfavourable) Expressed in all Expressed in all adrenal gland: 23.1 ASXL1 KIAA0978 ENSG00000171456 Additional sex combs like transcriptional regulator 1 20 32358344-32439319 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064156 Approved Nucleus
Nucleoli Endometrial cancer:2.86e-4 (unfavourable), Head and neck cancer:9.16e-4 (favourable) Expressed in all Expressed in all testis: 68.2 ASXL2 ASXH2, FLJ10898, KIAA1685 ENSG00000143970 Additional sex combs like transcriptional regulator 2 2 25733753-25878516 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034646, HPA058040 Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 26.1 ATAD1 FLJ14600 ENSG00000138138 ATPase family, AAA domain containing 1 10 87751512-87841343 Enzymes, Predicted membrane proteins Evidence at protein level HPA037569 Uncertain Approved Nucleus
Nucleoli
Mitochondria Renal cancer:3.98e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 28.5 ATAD3A FLJ10709 ENSG00000197785 ATPase family, AAA domain containing 3A 1 1512151-1534687 Predicted intracellular proteins Evidence at protein level HPA058968, HPA064867, HPA065305 Approved Supported Mitochondria Liver cancer:5.90e-5 (unfavourable) Expressed in all Expressed in all appendix: 16.6 ATE1 ENSG00000107669 Arginyltransferase 1 10 121740421-121928801 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038444, HPA057549 Approved Supported Nucleus Renal cancer:2.67e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.2 ATF1 TREB36 ENSG00000123268 Activating transcription factor 1 12 50763710-50821122 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016222, HPA055069, HPA055406 Supported Validated Nucleoplasm Liver cancer:1.53e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.5 ATF2 CRE-BP1, CREB2, HB16, TREB7 ENSG00000115966 Activating transcription factor 2 2 175072250-175168382 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003769, HPA022134 Supported Validated Nucleoplasm Liver cancer:7.08e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 53.7 ATF3 ENSG00000162772 Activating transcription factor 3 1 212565334-212620777 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001562 Approved Validated Nucleus
Nucleoli Expressed in all Expressed in all smooth muscle: 445.6 ATF4 CREB-2, TAXREB67, TXREB ENSG00000128272 Activating transcription factor 4 22 39519695-39522685 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011596 Approved Supported Microtubule organizing center
Cytosol Renal cancer:9.77e-5 (unfavourable), Liver cancer:4.07e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 531.3 ATF6 ATF6A ENSG00000118217 Activating transcription factor 6 1 161766294-161964070 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA005935 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 40.6 ATF6B CREBL1, G13 ENSG00000213676 Activating transcription factor 6 beta 6 32098176-32128253 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA046871 Uncertain Supported Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 55.8 ATF7 ATFA ENSG00000170653 Activating transcription factor 7 12 53507856-53626410 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA003384 Approved Approved Nucleus
Cytosol Stomach cancer:2.10e-4 (unfavourable) Expressed in all Expressed in all endometrium: 40.1 ATF7IP FLJ10688, p621 ENSG00000171681 Activating transcription factor 7 interacting protein 12 14365632-14502935 Predicted intracellular proteins Evidence at protein level HPA016578, HPA023505 Supported Validated Nucleoplasm
Nuclear bodies Glioma:7.91e-4 (favourable) Expressed in all Expressed in all testis: 61.7 ATG101 C12orf44, FLJ11773 ENSG00000123395 Autophagy related 101 12 52069246-52077494 Predicted intracellular proteins Evidence at protein level HPA039904 Approved Liver cancer:8.07e-7 (unfavourable) Expressed in all Expressed in all gallbladder: 43.8 ATG12 APG12, APG12L ENSG00000145782 Autophagy related 12 5 115828200-115841858 Predicted intracellular proteins Evidence at protein level CAB013272 Uncertain Renal cancer:1.54e-7 (unfavourable), Liver cancer:1.36e-4 (unfavourable), Thyroid cancer:4.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.2 ATG13 KIAA0652 ENSG00000175224 Autophagy related 13 11 46617527-46674818 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039350 Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:8.59e-5 (unfavourable) Expressed in all Expressed in all testis: 111.4 ATG14 ATG14L, KIAA0831 ENSG00000126775 Autophagy related 14 14 55366392-55411858 Predicted intracellular proteins Evidence at protein level CAB037242 Uncertain Liver cancer:1.63e-4 (unfavourable), Renal cancer:1.95e-4 (favourable) Expressed in all Expressed in all bone marrow: 17.2 ATG16L2 ATG16B, FLJ00012, WDR80 ENSG00000168010 Autophagy related 16-like 2 11 72814308-72843674 Predicted intracellular proteins Evidence at protein level HPA045444, HPA050312 Approved Validated Nucleoplasm Renal cancer:3.39e-4 (unfavourable), Pancreatic cancer:7.06e-4 (favourable) Expressed in all Expressed in all spleen: 101.0 ATG2A KIAA0404 ENSG00000110046 Autophagy related 2A 11 64894546-64917248 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038715 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:4.79e-5 (favourable) Expressed in all Expressed in all bone marrow: 39.0 ATG2B C14orf103, FLJ10242 ENSG00000066739 Autophagy related 2B 14 96279202-96363870 Predicted intracellular proteins Evidence at protein level HPA000880, HPA001427, HPA019665 Approved Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 16.8 ATG3 APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96 ENSG00000144848 Autophagy related 3 3 112532509-112562046 Predicted intracellular proteins Evidence at protein level CAB037260, HPA040471 Supported Supported Plasma membrane
Cytosol Liver cancer:9.35e-6 (unfavourable), Prostate cancer:1.59e-4 (unfavourable), Cervical cancer:6.82e-4 (favourable) Expressed in all Expressed in all testis: 154.2 ATG4A APG4A, AUTL2 ENSG00000101844 Autophagy related 4A, cysteine peptidase X 108091668-108154671 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036374, HPA064759 Uncertain Approved Actin filaments
Microtubules Breast cancer:1.36e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.7 ATG4B APG4B, AUTL1, DKFZp586D1822, KIAA0943 ENSG00000168397 Autophagy related 4B, cysteine peptidase 2 241637213-241673857 Enzymes, Predicted intracellular proteins Evidence at protein level CAB037195, HPA069803 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.79e-4 (unfavourable), Colorectal cancer:6.85e-4 (unfavourable), Urothelial cancer:9.64e-4 (favourable) Expressed in all Expressed in all testis: 43.9 ATG4C APG4C, AUTL1, AUTL3, FLJ14867 ENSG00000125703 Autophagy related 4C, cysteine peptidase 1 62784135-62865513 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007049 Approved Approved Nucleoplasm
Cytosol Colorectal cancer:9.83e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 23.6 ATG4D APG4-D, APG4D, AUTL4 ENSG00000130734 Autophagy related 4D, cysteine peptidase 19 10543895-10553418 Enzymes, Predicted intracellular proteins Evidence at protein level HPA067683 Approved Renal cancer:2.39e-7 (favourable), Cervical cancer:3.18e-5 (favourable), Stomach cancer:5.03e-4 (favourable), Pancreatic cancer:9.95e-4 (favourable) Expressed in all Expressed in all small intestine: 25.7 ATG5 APG5, APG5L, ASP, hAPG5 ENSG00000057663 Autophagy related 5 6 106184476-106325820 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034432, CAB037309, HPA042973 Supported Approved Centrosome Renal cancer:8.73e-4 (unfavourable), Liver cancer:8.84e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 32.1 ATG7 APG7L, DKFZp434N0735, GSA7 ENSG00000197548 Autophagy related 7 3 11272309-11557665 Predicted intracellular proteins Evidence at protein level HPA007639, CAB018771 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.41e-4 (unfavourable), Renal cancer:9.55e-4 (favourable), Colorectal cancer:9.66e-4 (favourable) Expressed in all Expressed in all testis: 39.9 ATG9A APG9L1, FLJ22169 ENSG00000198925 Autophagy related 9A 2 219209772-219229717 Predicted membrane proteins Evidence at protein level HPA059551 Uncertain Supported Vesicles Liver cancer:2.18e-5 (unfavourable) Expressed in all Expressed in all testis: 112.6 ATHL1 FLJ22635 ENSG00000142102 ATH1, acid trehalase-like 1 (yeast) 11 289135-296107 Predicted intracellular proteins Evidence at protein level HPA039383, HPA058829 Uncertain Validated Cytosol Urothelial cancer:5.12e-4 (favourable) Expressed in all Expressed in all lymph node: 74.8 ATIC AICARFT, IMPCHASE, PURH ENSG00000138363 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2 215311817-215349773 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013462, HPA021012 Supported Validated Plasma membrane
Cytosol Liver cancer:1.99e-7 (unfavourable), Renal cancer:8.77e-4 (unfavourable) Expressed in all Expressed in all placenta,rectum: 44.5 ATL2 ARL6IP2 ENSG00000119787 Atlastin GTPase 2 2 38294880-38377285 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029108 Approved Endometrial cancer:4.51e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 100.9 ATL3 DKFZP564J0863 ENSG00000184743 Atlastin GTPase 3 11 63624087-63671921 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065702 Supported Endoplasmic reticulum Pancreatic cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all testis: 66.0 ATM ATA, ATC, ATD, ATDC, TEL1, TELO1 ENSG00000149311 ATM serine/threonine kinase 11 108222484-108369102 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000102, HPA067142 Supported Supported Nucleoplasm Expressed in all Expressed in all lymph node: 41.6 ATMIN ASCIZ, KIAA0431, ZNF822 ENSG00000166454 ATM interactor 16 81035847-81047358 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054967, HPA066900 Approved Supported Nuclear bodies Renal cancer:6.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 60.2 ATN1 B37, D12S755E, DRPLA ENSG00000111676 Atrophin 1 12 6924463-6942321 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031619 Supported Validated Nucleoplasm Liver cancer:7.20e-4 (unfavourable) Expressed in all Expressed in all ovary: 139.3 ATOX1 HAH1 ENSG00000177556 Antioxidant 1 copper chaperone 5 151742316-151772532 Predicted intracellular proteins Evidence at protein level HPA055036 Approved Nucleoplasm
Plasma membrane Pancreatic cancer:9.57e-4 (favourable) Expressed in all Expressed in all thyroid gland: 151.1 ATP11A ATPIH, ATPIS, KIAA1021 ENSG00000068650 ATPase, class VI, type 11A 13 112690329-112887168 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035583, HPA035584 Approved Validated Vesicles Renal cancer:7.44e-4 (favourable) Expressed in all Expressed in all lung: 59.2 ATP11B ATPIF, ATPIR, KIAA0956 ENSG00000058063 ATPase, class VI, type 11B 3 182793500-182921635 Enzymes, Predicted membrane proteins, Transporters Evidence at protein level HPA036237, HPA036238 Uncertain Approved Microtubule organizing center
Cytosol Pancreatic cancer:1.09e-4 (unfavourable), Endometrial cancer:3.44e-4 (unfavourable) Expressed in all Expressed in all testis: 57.7 ATP13A1 ATP13A, CGI-152, FLJ31858, KIAA1825 ENSG00000105726 ATPase type 13A1 19 19645198-19663693 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA031798, HPA049717 Approved Approved Vesicles Renal cancer:6.51e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 51.5 ATP13A2 CLN12, HSA9947, PARK9 ENSG00000159363 ATPase type 13A2 1 16985958-17011928 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB037038, CAB037111, HPA050910, HPA054717 Approved Liver cancer:3.33e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 75.0 ATP13A3 AFURS1 ENSG00000133657 ATPase type 13A3 3 194402672-194498364 Predicted membrane proteins Evidence at protein level HPA029471 Approved Approved Nucleoli
Plasma membrane
Cytosol Pancreatic cancer:1.60e-4 (unfavourable), Renal cancer:1.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 146.4 ATP1A1 ENSG00000163399 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1 116372668-116410261 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB018702, CAB069993 Supported Renal cancer:8.98e-8 (favourable), Liver cancer:1.42e-4 (unfavourable), Urothelial cancer:4.01e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 2441.5 ATP1B1 ATP1B ENSG00000143153 ATPase, Na+/K+ transporting, beta 1 polypeptide 1 169105697-169132722 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA012911 Supported Renal cancer:7.08e-7 (favourable) Expressed in all Expressed in all kidney: 1327.1 ATP1B3 CD298, FLJ29027 ENSG00000069849 ATPase, Na+/K+ transporting, beta 3 polypeptide 3 141876124-141926514 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB020697, HPA048963 Supported Supported Plasma membrane Liver cancer:6.32e-6 (unfavourable), Renal cancer:1.29e-5 (unfavourable), Endometrial cancer:5.19e-5 (favourable) Expressed in all Expressed in all skin: 310.5 ATP2A2 ATP2B, DAR, SERCA2 ENSG00000174437 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 12 110280756-110351093 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA062605, HPA067892 Supported Supported Nucleoplasm Expressed in all Expressed in all skeletal muscle: 1006.6 ATP2A3 SERCA3 ENSG00000074370 ATPase, Ca++ transporting, ubiquitous 17 3923870-3964464 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007180, CAB010882 Approved Cervical cancer:4.69e-5 (favourable), Head and neck cancer:2.51e-4 (favourable) Expressed in all Expressed in all lymph node: 119.9 ATP2B1 PMCA1 ENSG00000070961 ATPase, Ca++ transporting, plasma membrane 1 12 89588049-89709300 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB005605, HPA011166, HPA012945 Supported Supported Plasma membrane Liver cancer:7.74e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.0 ATP2B4 ATP2B2, MXRA1, PMCA4 ENSG00000058668 ATPase, Ca++ transporting, plasma membrane 4 1 203626561-203744081 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB016118, HPA040431 Supported Supported Plasma membrane Renal cancer:1.21e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 251.3 ATP2C1 ATP2C1A, BCPM, KIAA1347, PMR1, SPCA1 ENSG00000017260 ATPase, Ca++ transporting, type 2C, member 1 3 130850595-131016712 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB010207, HPA035116, HPA069684 Supported Validated Golgi apparatus Liver cancer:5.06e-6 (unfavourable), Pancreatic cancer:1.52e-4 (unfavourable), Renal cancer:1.55e-4 (favourable) Expressed in all Expressed in all prostate: 136.8 ATP5A1 ATP5A, ATP5AL2, ATPM, hATP1, OMR, ORM ENSG00000152234 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 18 46080248-46104334 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013067, HPA040622, HPA044202 Supported Supported Mitochondria Renal cancer:1.22e-15 (favourable) Expressed in all Expressed in all parathyroid gland: 853.0 ATP5B ATPSB ENSG00000110955 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 12 56638175-56646068 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001520, HPA001528, CAB017527 Supported Validated Mitochondria Renal cancer:1.43e-9 (favourable), Breast cancer:7.17e-6 (unfavourable) Expressed in all Expressed in all heart muscle: 1257.9 ATP5C1 ATP5C, ATP5CL1 ENSG00000165629 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 10 7788129-7807815 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060949 Approved Renal cancer:9.26e-4 (favourable) Expressed in all Expressed in all heart muscle: 446.4 ATP5D ENSG00000099624 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 19 1241746-1244826 Predicted intracellular proteins Evidence at protein level HPA002865 Uncertain Renal cancer:3.46e-5 (favourable), Endometrial cancer:1.23e-4 (favourable), Pancreatic cancer:4.60e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 217.7 ATP5E ENSG00000124172 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 20 59025467-59032382 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.82e-4 (unfavourable) Expressed in all Expressed in all appendix: 137.1 ATP5F1 ENSG00000116459 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1 111448864-111462773 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA046067, HPA057347 Supported Supported Nucleoplasm
Mitochondria Renal cancer:3.26e-9 (favourable), Stomach cancer:8.07e-4 (favourable) Expressed in all Expressed in all heart muscle: 51.1 ATP5G1 ATP5G ENSG00000159199 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 17 48892765-48895871 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:8.24e-6 (favourable), Cervical cancer:3.88e-4 (favourable) Expressed in all Expressed in all heart muscle: 406.5 ATP5G2 ENSG00000135390 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 12 53632726-53677408 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA051469 Approved Expressed in all Expressed in all fallopian tube: 769.8 ATP5G3 ENSG00000154518 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 2 175176258-175184607 Predicted membrane proteins Evidence at transcript level Renal cancer:2.31e-6 (favourable), Head and neck cancer:6.01e-4 (unfavourable), Colorectal cancer:9.90e-4 (favourable) Expressed in all Expressed in all heart muscle: 525.2 ATP5H ATP5JD, ATPQ ENSG00000167863 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 17 75038863-75046985 Predicted intracellular proteins Evidence at protein level HPA042777, HPA048459 Supported Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all heart muscle: 622.4 ATP5I ENSG00000169020 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E 4 672436-674338 Predicted intracellular proteins Evidence at protein level HPA035010 Supported Validated Mitochondria Expressed in all Expressed in all skeletal muscle: 541.6 ATP5J ATP5, ATP5A, ATPM, CF6 ENSG00000154723 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 21 25716503-25735673 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031069 Supported Supported Mitochondria Renal cancer:2.37e-5 (favourable) Expressed in all Expressed in all heart muscle: 542.4 ATP5J2 ATP5JL, F1Fo-ATPase ENSG00000241468 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 7 99448475-99466331 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067267, HPA070412 Approved Supported Nucleoplasm
Mitochondria Head and neck cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 463.2 ATP5L ATP5JG ENSG00000167283 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 11 118401154-118431496 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044629 Approved Supported Mitochondria Renal cancer:4.09e-5 (favourable) Expressed in all Expressed in all kidney: 116.1 ATP5O ATPO, OSCP ENSG00000241837 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 21 33903453-33915980 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016209, HPA041394 Supported Supported Mitochondria Renal cancer:9.34e-4 (favourable) Expressed in all Expressed in all heart muscle: 518.0 ATP5SL FLJ10241 ENSG00000105341 ATP5S-like 19 41431318-41440717 Predicted intracellular proteins Evidence at protein level HPA041427 Approved Approved Mitochondria Renal cancer:4.07e-5 (favourable), Liver cancer:1.77e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 51.3 ATP6AP1 16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3 ENSG00000071553 ATPase, H+ transporting, lysosomal accessory protein 1 X 154428632-154436516 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB015218 Uncertain Approved Plasma membrane
Microtubules
Cytosol Renal cancer:5.26e-8 (favourable), Breast cancer:2.40e-4 (unfavourable), Glioma:7.82e-4 (unfavourable), Pancreatic cancer:7.83e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 205.5 ATP6AP2 APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR ENSG00000182220 ATPase, H+ transporting, lysosomal accessory protein 2 X 40580908-40606637 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003156 Approved Renal cancer:2.01e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 899.3 ATP6V0A1 a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1 ENSG00000033627 ATPase, H+ transporting, lysosomal V0 subunit a1 17 42458844-42522611 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA022144 Supported Approved Nuclear speckles
Golgi apparatus
Vesicles
Cytosol Renal cancer:1.28e-4 (favourable), Pancreatic cancer:2.05e-4 (favourable), Urothelial cancer:6.90e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 201.5 ATP6V0A2 a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1 ENSG00000185344 ATPase, H+ transporting, lysosomal V0 subunit a2 12 123712318-123761755 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044279 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all skin: 15.2 ATP6V0B ATP6F, HATPL, VMA16 ENSG00000117410 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1 43974487-43978295 Predicted membrane proteins Evidence at transcript level HPA044281 Approved Cytosol Renal cancer:3.62e-6 (favourable), Pancreatic cancer:3.24e-4 (favourable), Liver cancer:4.79e-4 (unfavourable), Urothelial cancer:8.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 181.8 ATP6V0C ATP6C, ATP6L, ATPL, VATL, Vma3 ENSG00000185883 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 16 2513870-2520218 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065100 Approved Cytosol Renal cancer:1.07e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 424.2 ATP6V0D1 ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD ENSG00000159720 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 16 67438014-67481237 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA016938 Uncertain Renal cancer:1.76e-8 (favourable), Pancreatic cancer:1.20e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 187.6 ATP6V0E1 ATP6H, ATP6V0E, M9.2 ENSG00000113732 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 5 172983757-173035445 Predicted membrane proteins Evidence at transcript level Expressed in all Expressed in all epididymis: 758.5 ATP6V0E2 ATP6V0E2L, C7orf32 ENSG00000171130 ATPase, H+ transporting V0 subunit e2 7 149872968-149880698 Predicted membrane proteins Evidence at transcript level Renal cancer:8.26e-7 (favourable), Pancreatic cancer:5.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 261.8 ATP6V1A ATP6A1, ATP6V1A1, VA68, Vma1, VPP2 ENSG00000114573 ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 3 113747019-113812056 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB006910, HPA035083, HPA035084 Approved Supported Nucleus
Vesicles
Cytosol Renal cancer:3.82e-12 (favourable) Expressed in all Expressed in all cerebral cortex: 151.8 ATP6V1B2 ATP6B2, HO57, VATB, Vma2, VPP3 ENSG00000147416 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 8 20197367-20226819 Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA008147 Supported Supported Vesicles Renal cancer:8.41e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 305.1 ATP6V1C1 ATP6C, ATP6D, VATC, Vma5 ENSG00000155097 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 8 103021063-103073051 Predicted intracellular proteins, Transporters Evidence at protein level HPA023943, HPA057297 Approved Supported Nucleoplasm
Cytosol Liver cancer:8.82e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 123.4 ATP6V1D ATP6M, VATD, VMA8 ENSG00000100554 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 14 67294371-67360265 Predicted intracellular proteins Evidence at protein level HPA031515, HPA057316 Supported Approved Nucleoplasm Renal cancer:7.60e-13 (favourable) Expressed in all Expressed in all cerebral cortex: 196.2 ATP6V1E1 ATP6E, ATP6E2, ATP6V1E, P31, Vma4 ENSG00000131100 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 22 17592136-17628818 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB009528, CAB018699, HPA029196 Supported Approved Nucleoplasm Renal cancer:7.66e-8 (favourable), Liver cancer:1.56e-5 (unfavourable), Prostate cancer:4.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 302.2 ATP6V1F ATP6S14, VATF, Vma7 ENSG00000128524 ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 7 128862826-128865844 Predicted intracellular proteins, Transporters Evidence at protein level CAB009529, HPA048700, HPA062011 Supported Renal cancer:2.49e-5 (favourable), Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 288.9 ATP6V1G1 ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10 ENSG00000136888 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 9 114587746-114598373 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004615, HPA042898 Supported Supported Nucleus
Nucleoli Renal cancer:1.73e-7 (favourable) Expressed in all Expressed in all epididymis: 295.9 ATP6V1H CGI-11, SFD, SFDalpha, SFDbeta, VMA13 ENSG00000047249 ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 8 53715557-53843558 Predicted intracellular proteins, Transporters Evidence at protein level CAB009532, HPA023421 Approved Approved Actin filaments
Cytosol Renal cancer:1.46e-7 (favourable), Liver cancer:7.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 126.9 ATP8B1 ATPIC, BRIC, FIC1, PFIC, PFIC1 ENSG00000081923 ATPase, aminophospholipid transporter, class I, type 8B, member 1 18 57646426-57803101 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018673, HPA018674 Supported Colorectal cancer:2.60e-4 (favourable), Renal cancer:6.35e-4 (favourable) Expressed in all Expressed in all colon: 96.9 ATP9A ATPIIA, KIAA0611 ENSG00000054793 ATPase, class II, type 9A 20 51596514-51768634 Enzymes, Predicted membrane proteins Evidence at protein level CAB020699, HPA035630 Approved Renal cancer:5.67e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 156.2 ATP9B ATPIIB ENSG00000166377 ATPase, class II, type 9B 18 79069285-79378283 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029364 Approved Expressed in all Expressed in all testis: 39.0 ATPAF1 ATP11, Atp11p, FLJ22351 ENSG00000123472 ATP synthase mitochondrial F1 complex assembly factor 1 1 46632737-46673867 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028382, HPA044950 Approved Approved Mitochondria Renal cancer:5.33e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 172.7 ATPAF2 ATP12, Atp12p, LP3663, MGC29736 ENSG00000171953 ATP synthase mitochondrial F1 complex assembly factor 2 17 17977409-18039209 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023329, HPA059422 Supported Validated Cytosol Renal cancer:6.00e-5 (favourable), Endometrial cancer:4.95e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 23.1 ATPIF1 ATPI, ATPIP, IP, MGC1167, MGC8898 ENSG00000130770 ATPase inhibitory factor 1 1 28236109-28246906 Predicted intracellular proteins Evidence at protein level HPA027999 Supported Validated Mitochondria Endometrial cancer:6.38e-8 (favourable), Ovarian cancer:8.20e-4 (favourable) Expressed in all Expressed in all heart muscle: 357.7 ATRAID APR3, C2orf28, HSPC013, p18 ENSG00000138085 All-trans retinoic acid-induced differentiation factor 2 27212027-27217178 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051353 Uncertain Expressed in all Expressed in all epididymis: 511.9 ATRN DPPT-L, MGCA ENSG00000088812 Attractin 20 3471040-3651122 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008853 Uncertain Approved Cytosol Renal cancer:2.19e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 83.4 ATRX JMS, MRX52, RAD54, XH2, XNP ENSG00000085224 Alpha thalassemia/mental retardation syndrome X-linked X 77504878-77786269 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001906, CAB009372, HPA064684, CAB068176 Supported Supported Nuclear bodies Expressed in all Expressed in all parathyroid gland: 53.5 ATXN1 ATX1, D6S504E, SCA1 ENSG00000124788 Ataxin 1 6 16299112-16761491 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008335, HPA070756 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all cerebral cortex: 17.5 ATXN10 E46L, FLJ37990, SCA10 ENSG00000130638 Ataxin 10 22 45671798-45845307 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049531 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 83.7 ATXN1L BOAT1 ENSG00000224470 Ataxin 1-like 16 71845991-71885268 Predicted intracellular proteins Evidence at protein level HPA062596, HPA062789 Validated Nucleus Renal cancer:5.33e-8 (favourable), Urothelial cancer:8.42e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.9 ATXN2 ATX2, SCA2, TNRC13 ENSG00000204842 Ataxin 2 12 111452214-111599676 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018295, HPA020339, HPA021146 Supported Validated Cytosol Liver cancer:2.66e-4 (unfavourable) Expressed in all Expressed in all testis: 41.1 ATXN2L A2D, A2lp ENSG00000168488 Ataxin 2-like 16 28823035-28837237 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041506, HPA043391, HPA071955 Approved Validated Cytosol Renal cancer:7.99e-7 (unfavourable), Liver cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all testis: 187.5 ATXN7 ADCAII, OPCA3, SCA7 ENSG00000163635 Ataxin 7 3 63864557-64003462 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034989 Supported Nucleoplasm
Cytosol Head and neck cancer:1.22e-4 (favourable) Expressed in all Expressed in all testis: 33.6 ATXN7L3 DKFZp761G2113 ENSG00000087152 Ataxin 7-like 3 17 44191805-44200113 Predicted intracellular proteins Evidence at protein level HPA064316 Supported Approved Nuclear speckles
Plasma membrane Renal cancer:2.87e-4 (unfavourable), Liver cancer:4.03e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 84.0 ATXN7L3B lnc-SCA7 ENSG00000253719 Ataxin 7-like 3B 12 74537827-74545430 Predicted intracellular proteins Evidence at protein level HPA056612 Approved Nucleoplasm Renal cancer:2.25e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 61.7 AUH ENSG00000148090 AU RNA binding protein/enoyl-CoA hydratase 9 91213815-91361913 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA004171 Supported Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all kidney: 65.0 AUP1 ENSG00000115307 Ancient ubiquitous protein 1 2 74526645-74529939 Predicted membrane proteins Evidence at protein level HPA007674 Approved Approved Nucleoplasm
Vesicles Renal cancer:2.97e-9 (unfavourable), Liver cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 57.1 AURKAIP1 AIP, AKIP, FLJ20608 ENSG00000175756 Aurora kinase A interacting protein 1 1 1373730-1375495 Predicted intracellular proteins Evidence at protein level HPA031821 Approved Supported Nucleoplasm
Mitochondria Renal cancer:8.11e-4 (favourable) Expressed in all Expressed in all testis: 148.5 AUTS2 FBRSL2, KIAA0442 ENSG00000158321 Autism susceptibility candidate 2 7 69598919-70793068 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000390 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all skin: 21.7 AVEN PDCD12 ENSG00000169857 Apoptosis, caspase activation inhibitor 15 33866227-34039176 Predicted intracellular proteins Evidence at protein level HPA020863 Approved Approved Plasma membrane
Actin filaments
Centrosome Renal cancer:5.29e-10 (unfavourable) Expressed in all Expressed in all smooth muscle: 19.1 AVL9 KIAA0241 ENSG00000105778 AVL9 homolog (S. cerevisiase) 7 32495426-32588721 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050957 Approved Approved Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 25.6 AXIN1 PPP1R49 ENSG00000103126 Axin 1 16 287440-352673 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012987 Approved Supported Nucleoli
Vesicles Liver cancer:3.38e-5 (unfavourable) Expressed in all Expressed in all spleen: 15.8 AXL ARK, JTK11, Tyro7, UFO ENSG00000167601 AXL receptor tyrosine kinase 19 41219203-41261766 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB032501, HPA037422, HPA037423 Uncertain Approved Intermediate filaments Renal cancer:2.53e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 54.0 AZI2 AZ2, FLJ21939, NAP1 ENSG00000163512 5-azacytidine induced 2 3 28315003-28349127 Predicted intracellular proteins Evidence at protein level HPA035258 Supported Liver cancer:1.95e-4 (unfavourable), Urothelial cancer:2.77e-4 (unfavourable) Expressed in all Expressed in all testis: 30.7 AZIN1 OAZI, OAZIN, ODC1L ENSG00000155096 Antizyme inhibitor 1 8 102826357-102893864 Predicted intracellular proteins Evidence at protein level HPA027948 Approved Approved Vesicles Expressed in all Expressed in all cerebral cortex: 133.8 B2M ENSG00000166710 Beta-2-microglobulin 15 44711477-44718877 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB002572, HPA006361 Supported Validated Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all lymph node: 5182.5 B3GALT6 beta3GalT6 ENSG00000176022 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1 1232265-1235041 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 12.1 B3GAT3 GlcAT-I ENSG00000149541 Beta-1,3-glucuronyltransferase 3 11 62615296-62622175 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051328 Approved Liver cancer:5.11e-6 (unfavourable), Glioma:5.96e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 37.0 B3GNT2 B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT ENSG00000170340 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 2 62196113-62224731 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA005997 Approved Approved Vesicles Pancreatic cancer:1.62e-4 (unfavourable) Expressed in all Expressed in all lung: 51.0 B3GNT5 B3GN-T5, beta3Gn-T5 ENSG00000176597 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 3 183253244-183298504 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017292 Uncertain Approved Nucleoli Renal cancer:1.30e-7 (unfavourable), Pancreatic cancer:7.23e-6 (unfavourable), Liver cancer:5.09e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 49.2 B4GALT1 beta4Gal-T1, GGTB2 ENSG00000086062 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 9 33104082-33167356 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA010806, HPA010807 Supported Validated Golgi apparatus Endometrial cancer:6.85e-7 (favourable), Lung cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 138.8 B4GALT2 beta4Gal-T2 ENSG00000117411 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 1 43978943-43991170 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007620, HPA047739 Supported Supported Golgi apparatus
Vesicles Liver cancer:2.96e-5 (unfavourable), Renal cancer:3.62e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 49.6 B4GALT3 beta4Gal-T3 ENSG00000158850 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 1 161171310-161177968 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010793 Approved Supported Golgi apparatus Renal cancer:7.12e-7 (unfavourable), Liver cancer:5.87e-5 (unfavourable) Expressed in all Expressed in all placenta: 31.0 B4GALT4 beta4Gal-T4 ENSG00000121578 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 3 119211732-119241103 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046819, HPA063546 Approved Supported Golgi apparatus Liver cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all epididymis: 74.6 B4GALT5 beta4GalT-V ENSG00000158470 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 20 49632945-49713878 Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.87e-5 (unfavourable), Liver cancer:2.69e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 59.9 B4GALT7 beta4Gal-T7, XGALT-1 ENSG00000027847 Xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 5 177600100-177610347 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042330 Supported Glioma:1.90e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 27.2 B9D1 B9, EPPB9, MKS9 ENSG00000108641 B9 protein domain 1 17 19337554-19378182 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022957 Approved Renal cancer:4.14e-4 (favourable) Expressed in all Expressed in all fallopian tube: 101.0 BABAM1 C19orf62, FLJ20571, HSPC142, MERIT40, NBA1 ENSG00000105393 BRISC and BRCA1 A complex member 1 19 17267350-17281249 Predicted intracellular proteins Evidence at protein level HPA054386, HPA068786 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all Expressed in all cerebral cortex: 84.4 BACE1 BACE ENSG00000186318 Beta-site APP-cleaving enzyme 1 11 117285207-117316259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB016358 Approved Supported Plasma membrane Urothelial cancer:6.76e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex,pancreas: 100.6 BACH1 BACH-1, BTBD24 ENSG00000156273 BTB and CNC homology 1, basic leucine zipper transcription factor 1 21 29194071-29630751 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034949 Approved Nucleus
Cytosol Pancreatic cancer:3.11e-5 (unfavourable), Renal cancer:7.14e-4 (unfavourable) Expressed in all Expressed in all placenta: 71.6 BAD BBC2, BCL2L8 ENSG00000002330 BCL2-associated agonist of cell death 11 64269830-64284704 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004205, HPA028185, HPA062105 Approved Validated Mitochondria Expressed in all Expressed in all cerebral cortex: 49.1 BAG1 ENSG00000107262 BCL2-associated athanogene 9 33247820-33264761 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002486, HPA018121 Supported Supported Nucleoplasm Renal cancer:2.22e-16 (favourable) Expressed in all Expressed in all parathyroid gland: 171.9 BAG3 ENSG00000151929 BCL2-associated athanogene 3 10 119651370-119677819 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018493, HPA020586 Supported Validated Plasma membrane
Cytosol Expressed in all Expressed in all skeletal muscle: 98.2 BAG4 SODD ENSG00000156735 BCL2-associated athanogene 4 8 38176533-38213301 Predicted intracellular proteins Evidence at protein level CAB013716, HPA018951 Approved Expressed in all Expressed in all cerebral cortex: 27.2 BAG6 BAT3, D6S52E, G3 ENSG00000204463 BCL2-associated athanogene 6 6 31639028-31652705 Predicted intracellular proteins Evidence at protein level CAB020704, HPA045116, HPA053291 Supported Validated Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 135.8 BAHD1 KIAA0945 ENSG00000140320 Bromo adjacent homology domain containing 1 15 40439721-40468242 Predicted intracellular proteins Evidence at protein level HPA041196 Supported Nucleoplasm Renal cancer:1.29e-10 (favourable), Breast cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all testis: 27.4 BAIAP2 BAP2 ENSG00000175866 BAI1-associated protein 2 17 81035122-81117432 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023310, HPA027421 Approved Validated Plasma membrane
Cytosol Urothelial cancer:7.58e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 125.1 BAK1 BAK, BCL2L7, CDN1 ENSG00000030110 BCL2-antagonist/killer 1 6 33572547-33580293 Predicted membrane proteins, Transporters Evidence at protein level CAB005029 Supported Renal cancer:1.64e-5 (unfavourable), Endometrial cancer:1.71e-4 (unfavourable), Liver cancer:4.52e-4 (unfavourable), Lung cancer:5.64e-4 (unfavourable) Expressed in all Expressed in all duodenum: 49.2 BANF1 BAF ENSG00000175334 Barrier to autointegration factor 1 11 66002079-66004149 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032896, HPA039242 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all fallopian tube: 237.4 BANP BEND1, DKFZp761H172, FLJ10177, FLJ20538, SMAR1, SMARBP1 ENSG00000172530 BTG3 associated nuclear protein 16 87949244-88118422 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047164 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all testis: 14.1 BAP1 hucep-6, KIAA0272, UCHL2 ENSG00000163930 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 3 52401013-52410350 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004322, HPA028814, HPA028815, HPA055560 Approved Validated Nucleoplasm
Cytosol Renal cancer:3.29e-7 (favourable) Expressed in all Expressed in all testis: 118.1 BAX BCL2L4 ENSG00000087088 BCL2-associated X protein 19 48954815-48961798 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level CAB004206, HPA027878 Approved Liver cancer:1.63e-5 (unfavourable) Expressed in all Expressed in all appendix: 83.2 BAZ1A ACF1, hACF1, WALp1, WCRF180 ENSG00000198604 Bromodomain adjacent to zinc finger domain, 1A 14 34752731-34875647 Predicted intracellular proteins Evidence at protein level HPA002730 Supported Uncertain Endoplasmic reticulum Renal cancer:1.31e-7 (unfavourable), Liver cancer:4.44e-4 (unfavourable) Expressed in all Expressed in all testis: 55.8 BAZ1B WBSCR10, WBSCR9, WSTF ENSG00000009954 Bromodomain adjacent to zinc finger domain, 1B 7 73440398-73522278 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB037081, CAB037158, HPA067010 Supported Supported Nuclear bodies Expressed in all Expressed in all parathyroid gland: 53.9 BAZ2A KIAA0314, TIP5, WALp3 ENSG00000076108 Bromodomain adjacent to zinc finger domain, 2A 12 56595596-56636816 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005782, HPA063806 Validated Nuclear speckles Liver cancer:2.72e-4 (unfavourable) Expressed in all Expressed in all testis: 82.6 BAZ2B WALp4 ENSG00000123636 Bromodomain adjacent to zinc finger domain, 2B 2 159318979-159616692 Predicted intracellular proteins Evidence at protein level HPA019819, HPA059292 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 55.7 BBIP1 bA348N5.3, BBIP10, BBS18, NCRNA00081 ENSG00000214413 BBSome interacting protein 1 10 110898730-110919274 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055206 Uncertain Expressed in all Expressed in all testis: 179.2 BBS1 FLJ23590 ENSG00000174483 Bardet-Biedl syndrome 1 11 66510606-66533627 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA058283 Uncertain Uncertain Midbody Mixed Expressed in all parathyroid gland: 64.4 BBS2 BBS ENSG00000125124 Bardet-Biedl syndrome 2 16 56466836-56520283 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041315 Approved Renal cancer:2.83e-6 (favourable) Expressed in all Expressed in all adrenal gland: 91.7 BBS4 ENSG00000140463 Bardet-Biedl syndrome 4 15 72686179-72738476 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039418 Approved Supported Cytosol Endometrial cancer:2.57e-4 (favourable) Expressed in all Expressed in all testis: 37.3 BBX HBP2, HSPC339, MDS001 ENSG00000114439 Bobby sox homolog (Drosophila) 3 107522936-107811324 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006049, HPA050646 Supported Validated Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 115.3 BCAM CD239, LU ENSG00000187244 Basal cell adhesion molecule (Lutheran blood group) 19 44809059-44821420 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005654 Uncertain Approved Nucleoli fibrillar center Renal cancer:5.94e-6 (favourable), Endometrial cancer:1.24e-5 (unfavourable), Colorectal cancer:2.31e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 172.9 BCAP29 BAP29, DKFZp686M2086 ENSG00000075790 B-cell receptor-associated protein 29 7 107579977-107629170 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA029215, HPA049694 Supported Approved Cytosol Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 185.4 BCAP31 6C6-Ag, BAP31, CDM, DXS1357E ENSG00000185825 B-cell receptor-associated protein 31 X 153700497-153724697 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA003906, CAB015350, CAB015424 Supported Approved Validated Endoplasmic reticulum Head and neck cancer:9.87e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 272.6 BCAS2 DAM1, Snt309, SPF27 ENSG00000116752 Breast carcinoma amplified sequence 2 1 114567557-114581639 Predicted intracellular proteins Evidence at protein level HPA067881 Supported Approved Nuclear speckles
Centrosome Liver cancer:8.23e-7 (unfavourable), Prostate cancer:4.27e-4 (unfavourable), Thyroid cancer:5.24e-4 (unfavourable), Renal cancer:6.49e-4 (favourable), Ovarian cancer:7.96e-4 (favourable) Expressed in all Expressed in all thyroid gland: 70.8 BCAS3 FLJ20128 ENSG00000141376 Breast carcinoma amplified sequence 3 17 60677453-61392838 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052409, HPA057289 Approved Supported Nucleoli Pancreatic cancer:1.23e-5 (favourable), Renal cancer:1.73e-5 (favourable), Cervical cancer:2.04e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 32.5 BCAT2 BCAM, BCT2 ENSG00000105552 Branched chain amino-acid transaminase 2, mitochondrial 19 48795062-48811029 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054091 Supported Renal cancer:3.68e-5 (favourable) Expressed in all Expressed in all adrenal gland: 54.3 BCCIP BCCIPalpha, TOK-1 ENSG00000107949 BRCA2 and CDKN1A interacting protein 10 125823546-125853695 Predicted intracellular proteins Evidence at protein level HPA038011 Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 89.2 BCKDHA MSU, OVD1A ENSG00000248098 Branched chain keto acid dehydrogenase E1, alpha polypeptide 19 41397460-41431345 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036640 Supported Renal cancer:5.33e-10 (favourable), Thyroid cancer:3.27e-5 (unfavourable), Head and neck cancer:9.37e-4 (favourable) Expressed in all Expressed in all thyroid gland: 56.6 BCKDHB ENSG00000083123 Branched chain keto acid dehydrogenase E1, beta polypeptide 6 80106647-80346270 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA031580 Approved Renal cancer:5.54e-9 (favourable) Expressed in all Expressed in all liver: 39.8 BCKDK ENSG00000103507 Branched chain ketoacid dehydrogenase kinase 16 31106107-31112791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017995, HPA056067 Supported Supported Mitochondria Expressed in all Expressed in all parathyroid gland: 33.6 BCL10 c-E10, CARMEN, CIPER, CLAP, mE10 ENSG00000142867 B-cell CLL/lymphoma 10 1 85266248-85277090 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB001944, HPA017925 Approved Approved Nucleoplasm Liver cancer:7.21e-7 (unfavourable), Colorectal cancer:2.51e-4 (favourable) Expressed in all Expressed in all gallbladder: 30.5 BCL2L1 Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52 ENSG00000171552 BCL2-like 1 20 31664452-31723989 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters Evidence at protein level HPA035734, CAB072801 Approved Approved Mitochondria Renal cancer:8.89e-5 (favourable), Pancreatic cancer:5.87e-4 (unfavourable), Endometrial cancer:9.10e-4 (unfavourable), Melanoma:9.57e-4 (favourable) Expressed in all Expressed in all gallbladder: 100.9 BCL2L11 BIM, BimEL, BimL, BimS, BOD ENSG00000153094 BCL2-like 11 (apoptosis facilitator) 2 111119378-111168447 Predicted intracellular proteins Evidence at protein level CAB026332 Approved Expressed in all Expressed in all thyroid gland: 33.4 BCL2L12 ENSG00000126453 BCL2-like 12 (proline rich) 19 49665142-49673916 Predicted intracellular proteins Evidence at protein level HPA020856 Approved Approved Cytosol Renal cancer:8.75e-5 (unfavourable) Expressed in all Expressed in all lymph node: 25.0 BCL2L13 BCL-RAMBO, MIL1 ENSG00000099968 BCL2-like 13 (apoptosis facilitator) 22 17628855-17730855 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002052, HPA030994, HPA050377 Uncertain Supported Mitochondria Renal cancer:1.96e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 45.9 BCL2L2 BCL-W, KIAA0271, PPP1R51 ENSG00000129473 BCL2-like 2 14 23298790-23311759 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB040539 Approved Renal cancer:1.99e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 89.1 BCL3 BCL4, D19S37 ENSG00000069399 B-cell CLL/lymphoma 3 19 44747705-44760044 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB002051, HPA047514 Approved Supported Nucleoplasm
Vesicles
Midbody Renal cancer:3.13e-14 (unfavourable), Melanoma:3.74e-4 (favourable), Glioma:5.58e-4 (unfavourable), Breast cancer:9.67e-4 (favourable) Expressed in all Expressed in all appendix: 30.9 BCL6 BCL5, BCL6A, LAZ3, ZBTB27, ZNF51 ENSG00000113916 B-cell CLL/lymphoma 6 3 187721377-187745727 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000307, HPA004899, HPA050645 Supported Validated Nucleoplasm
Golgi apparatus Renal cancer:1.27e-9 (unfavourable) Expressed in all Expressed in all adipose tissue: 112.8 BCL7A BCL7 ENSG00000110987 B-cell CLL/lymphoma 7A 12 122019422-122062044 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019762 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.54e-6 (favourable), Liver cancer:2.04e-4 (unfavourable), Colorectal cancer:6.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 13.8 BCL7B ENSG00000106635 B-cell CLL/lymphoma 7B 7 73536356-73558002 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049943, HPA058069 Approved Approved Nucleoplasm Renal cancer:4.38e-4 (favourable) Expressed in all Expressed in all bone marrow: 24.8 BCL7C ENSG00000099385 B-cell CLL/lymphoma 7C 16 30833626-30894960 Predicted intracellular proteins Evidence at protein level HPA018676, HPA052654 Uncertain Approved Nucleoplasm Cervical cancer:4.23e-4 (favourable) Expressed in all Expressed in all ovary: 30.3 BCL9L DLNB11 ENSG00000186174 B-cell CLL/lymphoma 9-like 11 118893875-118925608 Predicted intracellular proteins Evidence at protein level HPA049370, HPA053421 Uncertain Validated Nucleoplasm Expressed in all Expressed in all placenta: 34.8 BCLAF1 BTF, KIAA0164 ENSG00000029363 BCL2-associated transcription factor 1 6 136256863-136289851 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006484, HPA006669, HPA027770 Supported Validated Nuclear speckles Breast cancer:1.64e-4 (unfavourable), Colorectal cancer:3.44e-4 (favourable) Expressed in all Expressed in all bone marrow: 91.1 BCOR FLJ20285, KIAA1575 ENSG00000183337 BCL6 corepressor X 40049815-40177329 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056308, HPA066234 Validated Nucleus Liver cancer:1.30e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.3 BCORL1 CXorf10, FLJ11362 ENSG00000085185 BCL6 corepressor-like 1 X 129981107-130058083 Predicted intracellular proteins Evidence at protein level HPA031775, HPA031777, HPA068568 Uncertain Approved Nucleoplasm
Plasma membrane Endometrial cancer:2.20e-5 (unfavourable), Renal cancer:5.00e-4 (unfavourable) Expressed in all Expressed in all placenta: 18.2 BCR ALL, BCR1, CML, D22S11, D22S662, PHL ENSG00000186716 Breakpoint cluster region 22 23179704-23318037 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB010421, CAB018545, HPA038337 Approved Approved Nucleoplasm
Cytosol Renal cancer:9.15e-10 (favourable) Expressed in all Expressed in all cerebral cortex: 48.5 BCS1L BCS, BJS, h-BCS, Hs.6719 ENSG00000074582 BC1 (ubiquinol-cytochrome c reductase) synthesis-like 2 218658764-218663443 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037700, HPA037701 Supported Uncertain Vesicles Urothelial cancer:3.31e-4 (favourable) Expressed in all Expressed in all fallopian tube: 30.9 BDH2 DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308 ENSG00000164039 3-hydroxybutyrate dehydrogenase, type 2 4 103079435-103099883 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036028, HPA036029 Supported Supported Cytosol Renal cancer:4.45e-13 (favourable), Lung cancer:1.20e-4 (favourable), Endometrial cancer:5.21e-4 (favourable), Thyroid cancer:7.75e-4 (favourable) Expressed in all Expressed in all kidney: 452.1 BECN1 ATG6, VPS30 ENSG00000126581 Beclin 1, autophagy related 17 42810134-42833350 Predicted intracellular proteins Evidence at protein level CAB010143, HPA028949 Supported Approved Centrosome Expressed in all Expressed in all rectum: 71.6 BET1 hbet1 ENSG00000105829 Bet1 golgi vesicular membrane trafficking protein 7 93962762-94004382 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Glioma:9.38e-5 (unfavourable), Renal cancer:1.32e-4 (unfavourable) Expressed in all Expressed in all placenta: 51.4 BET1L GOLIM3, GS15 ENSG00000177951 Bet1 golgi vesicular membrane trafficking protein-like 11 167784-207428 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039819 Approved Approved Nucleus
Golgi apparatus Liver cancer:2.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.3 BEX4 BEXL1, FLJ10097 ENSG00000102409 Brain expressed, X-linked 4 X 103215092-103217246 Predicted intracellular proteins Evidence at transcript level HPA045105, HPA051935 Uncertain Approved Nucleus
Cytosol Renal cancer:2.54e-14 (favourable), Pancreatic cancer:9.41e-4 (favourable) Expressed in all Expressed in all epididymis: 318.7 BFAR BAR, RNF47 ENSG00000103429 Bifunctional apoptosis regulator 16 14632815-14669236 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Pancreatic cancer:4.74e-5 (unfavourable) Expressed in all Expressed in all placenta: 23.3 BHLHE40 BHLHB2, bHLHe40, DEC1, STRA13 ENSG00000134107 Basic helix-loop-helix family, member e40 3 4979116-4985323 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028922 Uncertain Supported Nuclear bodies Pancreatic cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all esophagus: 230.8 BICD2 KIAA0699 ENSG00000185963 Bicaudal D homolog 2 (Drosophila) 9 92711363-92764812 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023013, HPA024452 Supported Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.39e-4 (favourable) Expressed in all Expressed in all skin: 69.4 BID ENSG00000015475 BH3 interacting domain death agonist 22 17734138-17774770 Predicted intracellular proteins Evidence at protein level HPA000722, CAB003771 Supported Supported Cytosol Renal cancer:3.50e-13 (unfavourable) Expressed in all Expressed in all bone marrow: 54.6 BIRC2 API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48 ENSG00000110330 Baculoviral IAP repeat containing 2 11 102347211-102378670 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA005513, CAB020661 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all testis: 45.6 BIVM FLJ20159 ENSG00000134897 Basic, immunoglobulin-like variable motif containing 13 102799049-102841535 Predicted intracellular proteins Evidence at protein level HPA050126 Approved Supported Nucleoplasm Expressed in all Expressed in all kidney: 17.8 BLCAP BC10 ENSG00000166619 Bladder cancer associated protein 20 37492472-37527931 Predicted intracellular proteins Evidence at protein level HPA047390 Approved Nucleoli Urothelial cancer:7.28e-5 (favourable), Endometrial cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 221.5 BLMH BH ENSG00000108578 Bleomycin hydrolase 17 30248195-30292056 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039548, HPA064307 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all skin: 140.2 BLOC1S1 BLOS1, BORCS1, GCN5L1 ENSG00000135441 Biogenesis of lysosomal organelles complex-1, subunit 1 12 55716037-55720087 Predicted intracellular proteins Evidence at protein level HPA021381 Approved Ovarian cancer:2.19e-4 (favourable), Cervical cancer:2.77e-4 (favourable) Expressed in all Expressed in all fallopian tube: 211.6 BLOC1S2 BLOS2, BORCS2, FLJ30135, MGC10120 ENSG00000196072 Biogenesis of lysosomal organelles complex-1, subunit 2 10 100273280-100286712 Predicted intracellular proteins Evidence at protein level HPA048088, HPA055010 Approved Expressed in all Expressed in all cerebral cortex: 102.1 BLOC1S4 BCAS4L, CNO, FLJ11230 ENSG00000186222 Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 4 6716055-6717671 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043840 Approved Approved Vesicles
Cytosol Liver cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all ovary: 12.7 BLOC1S6 HPS9, PA, PLDN ENSG00000104164 Biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 15 45587123-45615999 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039928 Approved Expressed in all Expressed in all thyroid gland: 83.6 BLVRA BLVR ENSG00000106605 Biliverdin reductase A 7 43758680-43807342 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019709, HPA042865, HPA054322 Approved Supported Cytosol Lung cancer:8.65e-4 (favourable) Expressed in all Expressed in all epididymis: 155.8 BLVRB FLR, SDR43U1 ENSG00000090013 Biliverdin reductase B 19 40447789-40465840 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041698, HPA041937 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:3.90e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 339.1 BLZF1 JEM-1 ENSG00000117475 Basic leucine zipper nuclear factor 1 1 169367970-169396540 Predicted intracellular proteins Evidence at protein level HPA025703, HPA027331, HPA067113 Supported Supported Nucleus
Golgi apparatus Renal cancer:2.33e-4 (unfavourable) Expressed in all Expressed in all testis: 58.0 BMI1 PCGF4, RNF51 ENSG00000168283 BMI1 proto-oncogene, polycomb ring finger 10 22321211-22331484 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011120, HPA030471, HPA030472 Supported Approved Nucleus
Nucleoli
Nuclear bodies
Cytosol Liver cancer:2.60e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 84.7 BMPR2 BMPR-II, BMPR3, BRK-3, PPH1, T-ALK ENSG00000204217 Bone morphogenetic protein receptor, type II (serine/threonine kinase) 2 202376936-202567751 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA017385, HPA049014 Approved Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all cerebral cortex: 36.5 BMS1 BMS1L, KIAA0187 ENSG00000165733 BMS1 ribosome biogenesis factor 10 42782801-42834937 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036589, HPA043081 Uncertain Validated Nucleus
Nucleoli Liver cancer:1.06e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.0 BNIP1 Nip1, SEC20 ENSG00000113734 BCL2/adenovirus E1B 19kDa interacting protein 1 5 173144442-173164387 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008009, HPA008149 Supported Supported Endoplasmic reticulum Expressed in all Expressed in all testis: 26.9 BNIP2 BNIP-2, Nip2 ENSG00000140299 BCL2/adenovirus E1B 19kDa interacting protein 2 15 59659146-59689534 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026843 Approved Renal cancer:2.19e-5 (unfavourable), Endometrial cancer:8.42e-4 (favourable) Expressed in all Expressed in all bone marrow: 84.4 BNIP3 Nip3 ENSG00000176171 BCL2/adenovirus E1B 19kDa interacting protein 3 10 131966455-131982013 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA003015, CAB011676 Supported Uncertain Cytosol Renal cancer:4.55e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 84.4 BNIP3L BNIP3a, Nix ENSG00000104765 BCL2/adenovirus E1B 19kDa interacting protein 3-like 8 26382898-26505636 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA015652, CAB025371 Supported Approved Nuclear speckles
Mitochondria Renal cancer:5.92e-5 (unfavourable), Thyroid cancer:3.95e-4 (unfavourable) Expressed in all Expressed in all placenta: 150.7 BOD1 FAM44B ENSG00000145919 Biorientation of chromosomes in cell division 1 5 173607514-173616660 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036293 Uncertain Liver cancer:2.49e-6 (unfavourable), Head and neck cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.3 BOD1L1 BOD1L, FAM44A, FLJ33215, KIAA1327 ENSG00000038219 Biorientation of chromosomes in cell division 1-like 1 4 13568738-13627723 Predicted intracellular proteins Evidence at protein level HPA036943, HPA037362, HPA041290 Approved Validated Nucleoplasm Renal cancer:3.48e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 38.8 BOLA1 CGI-143 ENSG00000178096 BolA family member 1 1 149887890-149900798 Predicted secreted proteins Evidence at protein level HPA007005 Approved Liver cancer:5.88e-4 (unfavourable), Ovarian cancer:6.41e-4 (favourable) Expressed in all Expressed in all duodenum: 16.0 BOLA2B ENSG00000169627 BolA family member 2B 16 30192934-30194306 Predicted intracellular proteins Evidence at protein level HPA045380, HPA046696 Supported Uncertain Nucleus Mixed Expressed in all lymph node: 33.1 BOLA3 ENSG00000163170 BolA family member 3 2 74135398-74147994 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053162 Uncertain Renal cancer:9.90e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 52.3 BOP1 KIAA0124 ENSG00000261236 Block of proliferation 1 8 144262102-144291370 Predicted intracellular proteins Evidence at protein level HPA047869, HPA066764 Approved Validated Nucleus
Nucleoli Renal cancer:2.23e-7 (unfavourable), Liver cancer:3.35e-5 (unfavourable) Expressed in all Expressed in all appendix: 25.1 BORCS6 C17orf59, FLJ20014 ENSG00000196544 BLOC-1 related complex subunit 6 17 8188333-8190907 Predicted intracellular proteins Evidence at protein level HPA045415, HPA060791 Uncertain Supported Centrosome
Cytosol Pancreatic cancer:2.60e-4 (favourable), Endometrial cancer:2.78e-4 (favourable) Expressed in all Expressed in all spleen: 7.1 BORCS7 C10orf32, FLJ40752 ENSG00000166275 BLOC-1 related complex subunit 7 10 102854223-102864961 Predicted intracellular proteins Evidence at protein level HPA037648 Approved Approved Nuclear speckles
Cytosol Renal cancer:9.08e-8 (favourable) Expressed in all Expressed in all thyroid gland: 91.2 BPGM ENSG00000172331 2,3-bisphosphoglycerate mutase 7 134646808-134679813 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016493, HPA028735 Supported Approved Nucleoli Renal cancer:1.54e-8 (favourable), Cervical cancer:7.95e-4 (favourable) Expressed in all Expressed in all placenta: 64.7 BPHL Bph-rp, MCNAA ENSG00000137274 Biphenyl hydrolase-like (serine hydrolase) 6 3118374-3153578 Predicted intracellular proteins Evidence at protein level HPA036752, HPA036753 Supported Approved Nucleoplasm
Mitochondria Renal cancer:5.16e-7 (favourable), Ovarian cancer:5.97e-4 (favourable) Expressed in all Expressed in all kidney: 111.5 BPNT1 ENSG00000162813 3'(2'), 5'-bisphosphate nucleotidase 1 1 220057482-220090462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048461 Approved Approved Nuclear speckles Renal cancer:6.38e-4 (favourable) Expressed in all Expressed in all small intestine: 49.6 BPTF FAC1, FALZ, NURF301 ENSG00000171634 Bromodomain PHD finger transcription factor 17 67825524-67984378 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029069, HPA048289 Approved Validated Nucleoplasm Renal cancer:8.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 66.3 BRAF BRAF1 ENSG00000157764 B-Raf proto-oncogene, serine/threonine kinase 7 140719327-140924764 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA001328, CAB004552, HPA071048 Approved Approved Vesicles
Cytosol Expressed in all Expressed in all testis: 41.6 BRAT1 BAAT1, C7orf27, MGC22916 ENSG00000106009 BRCA1-associated ATM activator 1 7 2537877-2555727 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029455, HPA076508 Approved Supported Nucleoplasm Renal cancer:3.90e-4 (unfavourable), Liver cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all testis: 14.9 BRCC3 BRCC36, C6.1A, CXorf53 ENSG00000185515 BRCA1/BRCA2-containing complex, subunit 3 X 155071420-155123074 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048737 Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 20.8 BRD1 BRL, BRPF2 ENSG00000100425 Bromodomain containing 1 22 49773283-49827512 Predicted intracellular proteins Evidence at protein level HPA000807, HPA001063 Approved Supported Nuclear speckles Expressed in all Expressed in all testis: 58.6 BRD2 D6S113E, FSRG1, KIAA9001, NAT, RING3 ENSG00000204256 Bromodomain containing 2 6 32968660-32981505 Predicted intracellular proteins Evidence at protein level HPA042816 Approved Validated Nuclear speckles Expressed in all Expressed in all thyroid gland: 101.5 BRD3 KIAA0043, ORFX, RING3L ENSG00000169925 Bromodomain containing 3 9 134030305-134068535 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051830 Approved Approved Nuclear bodies Renal cancer:2.71e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 21.4 BRD4 CAP, HUNK1, HUNKI, MCAP ENSG00000141867 Bromodomain containing 4 19 15235519-15332545 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015055, HPA061646, CAB068177, CAB068178 Supported Validated Nucleoplasm Expressed in all Expressed in all placenta: 41.6 BRD7 BP75, CELTIX1 ENSG00000166164 Bromodomain containing 7 16 50313487-50368934 Predicted intracellular proteins Evidence at protein level HPA042389, CAB046458, HPA060171 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.55e-4 (favourable), Melanoma:5.38e-4 (unfavourable) Expressed in all Expressed in all testis: 105.3 BRD8 p120, SMAP ENSG00000112983 Bromodomain containing 8 5 138139766-138178986 Predicted intracellular proteins Evidence at protein level HPA001841 Supported Approved Nucleoplasm
Mitochondria Liver cancer:1.09e-6 (unfavourable), Renal cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all testis: 147.8 BRD9 FLJ13441 ENSG00000028310 Bromodomain containing 9 5 850291-892824 Predicted intracellular proteins Evidence at protein level HPA021465, HPA023197 Uncertain Approved Nucleoplasm Liver cancer:5.88e-7 (unfavourable), Renal cancer:2.37e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 14.8 BRE BRCC4, BRCC45 ENSG00000158019 Brain and reproductive organ-expressed (TNFRSF1A modulator) 2 27889941-28338901 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA017926 Approved Supported Cytosol Liver cancer:6.33e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 190.4 BRF1 BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90 ENSG00000185024 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 14 105209286-105315589 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051918 Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:7.25e-6 (favourable), Renal cancer:1.13e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 21.7 BRF2 BRFU, FLJ11052, TFIIIB50 ENSG00000104221 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 8 37843268-37849904 Predicted intracellular proteins Evidence at protein level CAB019269, HPA023378 Supported Approved Nucleoli Expressed in all Expressed in all epididymis: 18.6 BRI3 ENSG00000164713 Brain protein I3 7 98252379-98310441 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042215 Uncertain Head and neck cancer:3.35e-4 (unfavourable) Expressed in all Expressed in all lung: 119.5 BRIX1 BRIX, BXDC2, FLJ11100 ENSG00000113460 BRX1, biogenesis of ribosomes 5 34915376-34925996 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039614 Approved Validated Nucleoli Renal cancer:3.07e-9 (unfavourable), Liver cancer:4.11e-8 (unfavourable), Endometrial cancer:1.10e-5 (unfavourable), Breast cancer:2.18e-4 (unfavourable), Ovarian cancer:6.34e-4 (favourable) Expressed in all Expressed in all placenta: 27.4 BRK1 C3orf10, HSPC300, MDS027 ENSG00000254999 BRICK1, SCAR/WAVE actin-nucleating complex subunit 3 10115592-10127190 Predicted intracellular proteins Evidence at protein level HPA060391 Approved Nuclear speckles
Cell Junctions Liver cancer:5.76e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 223.3 BRMS1 DKFZP564A063 ENSG00000174744 Breast cancer metastasis suppressor 1 11 66337333-66345125 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010824, HPA019637 Approved Approved Centrosome Liver cancer:6.74e-4 (unfavourable) Expressed in all Expressed in all skin: 36.3 BROX C1orf58, FLJ32421 ENSG00000162819 BRO1 domain and CAAX motif containing 1 222712553-222735196 Predicted intracellular proteins Evidence at protein level HPA031445 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 46.0 BRPF1 BR140 ENSG00000156983 Bromodomain and PHD finger containing, 1 3 9731729-9748018 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003359 Supported Approved Plasma membrane
Cytosol Liver cancer:3.20e-5 (unfavourable), Prostate cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all testis: 26.3 BRPF3 KIAA1286 ENSG00000096070 Bromodomain and PHD finger containing, 3 6 36196744-36232790 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022787 Uncertain Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 38.2 BRWD1 C21orf107, DCAF19, FLJ11315, N143, WDR9 ENSG00000185658 Bromodomain and WD repeat domain containing 1 21 39184176-39321559 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030943, HPA030944, HPA030945, CAB034184 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all cerebral cortex: 77.9 BSCL2 GNG3LG, SPG17 ENSG00000168000 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 11 62690275-62709845 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042394 Approved Renal cancer:7.55e-5 (favourable) Expressed in all Expressed in all testis: 249.9 BSDC1 FLJ10276, RP4-811H24.7 ENSG00000160058 BSD domain containing 1 1 32365103-32394731 Predicted intracellular proteins Evidence at protein level HPA031358, HPA031360 Approved Validated Golgi apparatus Head and neck cancer:8.82e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 111.3 BSG CD147, EMMPRIN, OK ENSG00000172270 Basigin (Ok blood group) 19 571277-583493 Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB002427, HPA036048, HPA074870 Supported Approved Vesicles Renal cancer:1.95e-6 (favourable), Liver cancer:5.48e-6 (unfavourable), Endometrial cancer:2.59e-4 (favourable) Expressed in all Expressed in all heart muscle: 585.9 BST2 CD317, tetherin ENSG00000130303 Bone marrow stromal cell antigen 2 19 17402939-17405648 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA017060 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:3.56e-9 (unfavourable), Testis cancer:4.22e-4 (unfavourable), Breast cancer:6.69e-4 (favourable) Expressed in all Expressed in all ovary: 585.6 BTAF1 MOT1, TAF(II)170, TAF-172, TAF172, TAFII170 ENSG00000095564 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 10 91923769-92030325 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA070682 Approved Nucleoplasm
Vesicles Renal cancer:4.04e-5 (unfavourable), Head and neck cancer:5.07e-4 (favourable) Expressed in all Expressed in all skin: 59.9 BTBD1 ENSG00000064726 BTB (POZ) domain containing 1 15 83016422-83067354 Predicted intracellular proteins Evidence at protein level HPA067671 Supported Renal cancer:6.21e-7 (favourable) Expressed in all Expressed in all skeletal muscle: 109.7 BTBD10 GMRP-1, GMRP1, MGC13007 ENSG00000148925 BTB (POZ) domain containing 10 11 13388001-13463297 Predicted intracellular proteins Evidence at protein level HPA046777 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all testis: 67.5 BTBD2 ENSG00000133243 BTB (POZ) domain containing 2 19 1985438-2034881 Predicted intracellular proteins Evidence at protein level Liver cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 75.1 BTBD3 dJ742J24.1, KIAA0952 ENSG00000132640 BTB (POZ) domain containing 3 20 11890723-11926609 Predicted intracellular proteins Evidence at protein level HPA041424, HPA042048 Uncertain Supported Vesicles Liver cancer:2.51e-5 (unfavourable), Lung cancer:6.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 59.7 BTBD6 BDPL ENSG00000184887 BTB (POZ) domain containing 6 14 105248490-105251093 Predicted intracellular proteins Evidence at protein level HPA031355 Approved Approved Nucleoplasm Renal cancer:6.51e-5 (favourable), Breast cancer:1.11e-4 (favourable), Pancreatic cancer:2.25e-4 (favourable) Expressed in all Expressed in all testis: 73.3 BTD ENSG00000169814 Biotinidase 3 15601341-15645822 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052275 Uncertain Renal cancer:2.60e-9 (favourable) Expressed in all Expressed in all epididymis: 52.1 BTF3 BTF3a, BTF3b, NACB ENSG00000145741 Basic transcription factor 3 5 73498408-73505635 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013007, HPA056420 Approved Supported Cytosol Expressed in all Expressed in all ovary: 1439.3 BTF3L4 MGC23908 ENSG00000134717 Basic transcription factor 3-like 4 1 52056125-52090716 Predicted intracellular proteins Evidence at protein level HPA067026 Approved Approved Nucleus
Cytosol Liver cancer:6.73e-8 (unfavourable), Renal cancer:4.43e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 72.4 BTG1 ENSG00000133639 B-cell translocation gene 1, anti-proliferative 12 92140278-92145897 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005972 Approved Nucleoplasm
Cytosol Renal cancer:1.95e-7 (unfavourable), Breast cancer:4.36e-5 (favourable) Expressed in all Expressed in all bone marrow: 261.6 BTG2 MGC126063, MGC126064, PC3, TIS21 ENSG00000159388 BTG family, member 2 1 203305491-203309602 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002355 Uncertain Approved Nucleoplasm
Vesicles Breast cancer:8.53e-4 (favourable) Expressed in all Expressed in all ovary: 662.9 BTN2A1 BT2.1, BTF1, BTN2.1 ENSG00000112763 Butyrophilin, subfamily 2, member A1 6 26457904-26476621 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019208 Approved Approved Plasma membrane Urothelial cancer:4.52e-5 (favourable), Renal cancer:5.90e-5 (unfavourable) Expressed in all Expressed in all placenta: 26.1 BTN3A1 BT3.1, BTF5, BTN3.1, CD277 ENSG00000026950 Butyrophilin, subfamily 3, member A1 6 26402237-26415216 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012565 Approved Uncertain Vesicles Renal cancer:4.15e-5 (unfavourable), Urothelial cancer:4.81e-4 (favourable) Expressed in all Expressed in all spleen: 114.2 BTN3A2 BTN3.2 ENSG00000186470 Butyrophilin, subfamily 3, member A2 6 26365159-26378320 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB019392 Uncertain Renal cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all spleen: 131.4 BTRC beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1 ENSG00000166167 Beta-transducin repeat containing E3 ubiquitin protein ligase 10 101354033-101557321 Predicted intracellular proteins Evidence at protein level HPA031156, CAB032986 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 34.1 BUB3 BUB3L ENSG00000154473 BUB3 mitotic checkpoint protein 10 123154277-123170467 Predicted intracellular proteins Evidence at protein level HPA003601, CAB037075 Supported Validated Nucleoplasm Renal cancer:3.81e-7 (unfavourable), Liver cancer:4.45e-5 (unfavourable), Cervical cancer:2.04e-4 (favourable) Expressed in all Expressed in all lymph node: 113.5 BUD13 Cwc26, fSAP71, MGC13125 ENSG00000137656 BUD13 homolog 11 116748170-116772988 Predicted intracellular proteins Evidence at protein level HPA038340, HPA038341 Approved Validated Nucleus Liver cancer:5.07e-5 (unfavourable) Expressed in all Expressed in all testis: 39.3 BUD31 Cwc14, EDG-2, EDG2, fSAP17, G10, YCR063W ENSG00000106245 BUD31 homolog 7 99408641-99419616 Predicted intracellular proteins Evidence at protein level HPA028943 Approved Approved Nucleus
Microtubules
Centrosome Renal cancer:9.66e-4 (unfavourable) Expressed in all Expressed in all testis: 101.5 BYSL ENSG00000112578 Bystin-like 6 41921188-41933046 Predicted intracellular proteins Evidence at protein level HPA031217, HPA031219 Supported Validated Nucleus
Nucleoli Renal cancer:2.15e-8 (unfavourable), Liver cancer:6.43e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 11.5 BZRAP1 KIAA0612, PRAX-1, RIM-BP1, RIMBP1 ENSG00000005379 Benzodiazepine receptor (peripheral) associated protein 1 17 58301228-58328760 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024662, HPA025244 Approved Pancreatic cancer:9.15e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 69.3 BZW1 BZAP45, KIAA0005 ENSG00000082153 Basic leucine zipper and W2 domains 1 2 200810594-200827338 Predicted intracellular proteins Evidence at protein level HPA047288, HPA053272 Uncertain Approved Vesicles Cervical cancer:4.28e-4 (unfavourable), Lung cancer:5.10e-4 (unfavourable) Expressed in all Expressed in all testis: 310.4 BZW2 HSPC028, MST017, MSTP017 ENSG00000136261 Basic leucine zipper and W2 domains 2 7 16646131-16706523 Predicted intracellular proteins Evidence at protein level HPA022813, HPA026709 Approved Approved Plasma membrane
Actin filaments
Cytosol Liver cancer:7.86e-8 (unfavourable), Renal cancer:6.01e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 167.1 C10orf10 DEPP, FIG, Fseg ENSG00000165507 Chromosome 10 open reading frame 10 10 44970981-44978810 Predicted secreted proteins Evidence at protein level CAB013687, HPA037819 Uncertain Approved Nucleus
Vesicles Renal cancer:2.29e-6 (unfavourable) Expressed in all Expressed in all adipose tissue: 236.8 C10orf2 FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL ENSG00000107815 Chromosome 10 open reading frame 2 10 100987367-100994401 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002532 Uncertain Expressed in all Expressed in all testis: 13.6 C10orf54 B7-H5, B7H5, GI24, SISP1, VISTA ENSG00000107738 Chromosome 10 open reading frame 54 10 71747559-71773498 Predicted membrane proteins Evidence at protein level HPA007968 Uncertain Approved Nucleoplasm Testis cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all spleen: 188.4 C10orf76 FLJ13114 ENSG00000120029 Chromosome 10 open reading frame 76 10 101845599-102056193 Predicted intracellular proteins Evidence at protein level HPA050913, HPA053580 Approved Approved Vesicles Expressed in all Expressed in all parathyroid gland: 25.9 C11orf1 FLJ23499 ENSG00000137720 Chromosome 11 open reading frame 1 11 111878935-111885975 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038410, HPA057519 Uncertain Validated Nucleoplasm Renal cancer:1.39e-4 (favourable), Endometrial cancer:9.32e-4 (favourable) Expressed in all Expressed in all testis: 103.8 C11orf24 DM4E3 ENSG00000171067 Chromosome 11 open reading frame 24 11 68261335-68272001 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012748 Uncertain Uncertain Nucleoplasm
Vesicles Renal cancer:1.60e-9 (unfavourable), Lung cancer:6.05e-4 (unfavourable), Glioma:9.83e-4 (unfavourable) Expressed in all Expressed in all small intestine: 67.2 C11orf30 EMSY ENSG00000158636 Chromosome 11 open reading frame 30 11 76444923-76553025 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012234, HPA050777 Supported Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 20.0 C11orf31 SELH ENSG00000211450 Chromosome 11 open reading frame 31 11 57741250-57743554 Predicted intracellular proteins Evidence at protein level HPA048362 Uncertain Approved Nucleus
Nucleoli Ovarian cancer:1.80e-4 (favourable), Liver cancer:4.30e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 69.9 C11orf49 FLJ22210, MGC4707 ENSG00000149179 Chromosome 11 open reading frame 49 11 46936689-47164385 Predicted intracellular proteins Evidence at protein level HPA040051, HPA040280 Uncertain Approved Nuclear speckles Liver cancer:2.18e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 57.4 C11orf54 PTD012 ENSG00000182919 Chromosome 11 open reading frame 54 11 93741591-93764749 Predicted intracellular proteins Evidence at protein level HPA040088, HPA040511 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:5.06e-6 (favourable) Expressed in all Expressed in all kidney: 539.9 C11orf57 FLJ10726 ENSG00000150776 Chromosome 11 open reading frame 57 11 112074086-112085150 Predicted intracellular proteins Evidence at protein level HPA039493, HPA039892 Approved Supported Cytosol Liver cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 27.2 C11orf58 SMAP ENSG00000110696 Chromosome 11 open reading frame 58 11 16613132-16756881 Predicted intracellular proteins Evidence at protein level HPA036591, HPA076406 Uncertain Approved Nucleoplasm
Endoplasmic reticulum Liver cancer:5.84e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 217.3 C11orf68 BLES03, P5326 ENSG00000175573 Chromosome 11 open reading frame 68 11 65916808-65919117 Predicted intracellular proteins Evidence at protein level HPA045938 Uncertain Approved Nucleus
Nucleoli Renal cancer:5.02e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 50.0 C11orf73 Hikeshi, HSPC138, HSPC179, OPI10 ENSG00000149196 Chromosome 11 open reading frame 73 11 86302211-86345931 Predicted intracellular proteins Evidence at protein level HPA035063, HPA035064 Approved Renal cancer:4.01e-12 (unfavourable), Liver cancer:8.81e-4 (unfavourable) Expressed in all Expressed in all endometrium: 46.3 C11orf74 FLJ38678, HEPIS ENSG00000166352 Chromosome 11 open reading frame 74 11 36594493-36659290 Predicted intracellular proteins Evidence at protein level HPA044880 Uncertain Approved Aggresome
Cytosol Expressed in all Expressed in all thyroid gland: 177.0 C11orf84 ENSG00000168005 Chromosome 11 open reading frame 84 11 63813388-63827718 Predicted intracellular proteins Evidence at protein level HPA040128, HPA050313 Uncertain Approved Nuclear speckles Liver cancer:1.53e-5 (unfavourable), Renal cancer:5.42e-5 (unfavourable) Expressed in all Expressed in all testis: 42.7 C11orf95 MGC3032 ENSG00000188070 Chromosome 11 open reading frame 95 11 63759892-63768775 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045002 Approved Intermediate filaments Expressed in all Expressed in all endometrium: 24.5 C11orf98 C11orf48 ENSG00000278615 Chromosome 11 open reading frame 98 11 62662816-62665217 Predicted intracellular proteins Evidence at transcript level Renal cancer:4.02e-6 (unfavourable), Liver cancer:5.85e-5 (unfavourable), Endometrial cancer:7.62e-4 (unfavourable) Expressed in all Expressed in all lymph node: 81.7 C12orf10 Gamm1, MYG, MYG1 ENSG00000139637 Chromosome 12 open reading frame 10 12 53299686-53307177 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038626, HPA038627 Approved Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 114.2 C12orf43 FLJ12448 ENSG00000157895 Chromosome 12 open reading frame 43 12 121000486-121016502 Predicted intracellular proteins Evidence at protein level HPA046148, HPA061739 Uncertain Validated Nucleoli
Golgi apparatus Liver cancer:1.29e-6 (unfavourable), Lung cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 20.7 C12orf45 MGC40397 ENSG00000151131 Chromosome 12 open reading frame 45 12 104986310-105049737 Predicted intracellular proteins Evidence at protein level HPA038722 Uncertain Approved Nucleoplasm
Nuclear membrane Renal cancer:4.58e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.8 C12orf57 C10, GRCC10 ENSG00000111678 Chromosome 12 open reading frame 57 12 6942978-6946003 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046182, HPA059163, HPA066043 Approved Supported Nuclear speckles Renal cancer:2.32e-7 (unfavourable), Pancreatic cancer:8.74e-4 (favourable) Expressed in all Expressed in all ovary: 522.7 C12orf65 FLJ38663, SPG55 ENSG00000130921 Chromosome 12 open reading frame 65 12 123232916-123257959 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038194, HPA057595 Uncertain Approved Nucleus
Mitochondria
Cytosol Liver cancer:4.29e-9 (unfavourable), Urothelial cancer:7.82e-5 (favourable) Expressed in all Expressed in all testis: 26.7 C12orf66 FLJ32549 ENSG00000174206 Chromosome 12 open reading frame 66 12 64186316-64222296 Predicted intracellular proteins Evidence at protein level HPA046743, HPA052855 Uncertain Validated Microtubules
Cytokinetic bridge
Mitotic spindle Expressed in all Expressed in all parathyroid gland: 12.1 C12orf73 DKFZp547P055, FLJ13975 ENSG00000204954 Chromosome 12 open reading frame 73 12 103950202-103965708 Predicted secreted proteins Evidence at protein level HPA038883 Uncertain Approved Plasma membrane
Centrosome
Mitochondria Urothelial cancer:1.61e-4 (favourable), Liver cancer:6.98e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex,thyroid gland: 17.8 C12orf76 FLJ40142 ENSG00000174456 Chromosome 12 open reading frame 76 12 110027028-110073686 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA039713, HPA042013 Uncertain Approved Plasma membrane
Actin filaments Renal cancer:5.74e-5 (unfavourable), Lung cancer:6.44e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 106.1 C14orf1 ERG28, NET51 ENSG00000133935 Chromosome 14 open reading frame 1 14 75649791-75661189 Predicted membrane proteins Evidence at protein level HPA043172, HPA063568 Approved Approved Nucleoplasm
Cytosol Renal cancer:4.30e-5 (favourable) Expressed in all Expressed in all testis: 77.0 C14orf119 FLJ20671 ENSG00000179933 Chromosome 14 open reading frame 119 14 23094765-23100462 Predicted intracellular proteins Evidence at protein level HPA003638 Uncertain Supported Mitochondria
Cytosol Thyroid cancer:3.30e-5 (favourable), Liver cancer:5.42e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 70.0 C14orf159 FLJ39975 ENSG00000133943 Chromosome 14 open reading frame 159 14 91060333-91225632 Predicted intracellular proteins Evidence at protein level HPA041423, HPA052932 Approved Supported Cytosol Renal cancer:3.77e-15 (favourable), Lung cancer:9.48e-5 (favourable), Endometrial cancer:4.28e-4 (favourable), Ovarian cancer:7.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 81.0 C14orf166 CGI-99, CLE, CLE7, LCRP369, RLLM1 ENSG00000087302 Chromosome 14 open reading frame 166 14 51989475-52010691 Predicted intracellular proteins Evidence at protein level HPA039824 Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 261.5 C14orf169 FLJ21802, MAPJD, NO66 ENSG00000170468 Chromosome 14 open reading frame 169 14 73490964-73493392 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003730 Supported Nucleoli Expressed in all Expressed in all testis: 17.7 C14orf2 MP68 ENSG00000156411 Chromosome 14 open reading frame 2 14 103912288-103928269 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058978, HPA060520 Supported Supported Nucleoli fibrillar center
Mitochondria Ovarian cancer:6.80e-4 (favourable) Expressed in all Expressed in all heart muscle: 206.9 C14orf93 FLJ12154 ENSG00000100802 Chromosome 14 open reading frame 93 14 22985908-23010166 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002569 Approved Approved Nucleus
Plasma membrane Breast cancer:5.05e-4 (favourable) Expressed in all Expressed in all skin: 21.7 C15orf38-AP3S2 ENSG00000250021 C15orf38-AP3S2 readthrough 15 89834308-89912882 Predicted intracellular proteins Evidence at protein level HPA040513, HPA047173, HPA049270, HPA052278 Uncertain Approved Vesicles Not detected Expressed in all cerebral cortex: 19.5 C15orf40 MGC29937 ENSG00000169609 Chromosome 15 open reading frame 40 15 82988441-83011641 Predicted intracellular proteins Evidence at protein level HPA042980 Approved Approved Nucleus
Cytosol Renal cancer:4.35e-4 (favourable) Expressed in all Expressed in all epididymis: 26.7 C15orf57 CCDC32, MGC20481 ENSG00000128891 Chromosome 15 open reading frame 57 15 40528683-40565057 Predicted intracellular proteins Evidence at protein level HPA041688 Uncertain Approved Nuclear speckles
Vesicles Expressed in all Expressed in all thyroid gland: 35.3 C16orf13 MGC13114 ENSG00000130731 Chromosome 16 open reading frame 13 16 634427-636366 Predicted intracellular proteins Evidence at protein level HPA044004 Uncertain Renal cancer:1.73e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.1 C16orf52 ENSG00000185716 Chromosome 16 open reading frame 52 16 22007638-22087534 Predicted membrane proteins Evidence at transcript level Expressed in all Expressed in all parathyroid gland: 39.5 C16orf58 FLJ13868 ENSG00000140688 Chromosome 16 open reading frame 58 16 31489471-31509309 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024406 Uncertain Approved Nucleoplasm
Nucleoli
Golgi apparatus
Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 81.3 C16orf62 MGC16824 ENSG00000103544 Chromosome 16 open reading frame 62 16 19555240-19706793 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042969, HPA053547 Uncertain Approved Mitochondria Renal cancer:1.31e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 68.5 C16orf70 C16orf6, FLJ12076, lin-10, LIN10 ENSG00000125149 Chromosome 16 open reading frame 70 16 67109958-67148539 Predicted intracellular proteins Evidence at protein level HPA041131, HPA041214 Approved Approved Nuclear speckles
Cytosol Expressed in all Expressed in all parathyroid gland: 33.2 C16orf72 FLJ41272, PRO0149 ENSG00000182831 Chromosome 16 open reading frame 72 16 9091648-9121640 Predicted intracellular proteins Evidence at protein level HPA041568, HPA067492 Uncertain Approved Nucleoplasm
Vesicles Head and neck cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 67.7 C16orf91 CCSMST1, gs103 ENSG00000174109 Chromosome 16 open reading frame 91 16 1419744-1420800 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:1.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 16.6 C17orf49 BAP18, HEPIS, MGC49942 ENSG00000258315 Chromosome 17 open reading frame 49 17 7014495-7017525 Predicted intracellular proteins Evidence at protein level HPA022961, HPA024457 Supported Uncertain Nucleoplasm
Cytosol Mixed Expressed in all lymph node: 110.2 C17orf58 ENSG00000186665 Chromosome 17 open reading frame 58 17 67991101-67993649 Predicted intracellular proteins Evidence at transcript level HPA023036 Uncertain Approved Plasma membrane
Cytosol Renal cancer:1.31e-10 (unfavourable), Liver cancer:8.99e-4 (unfavourable) Expressed in all Expressed in all placenta: 58.5 C17orf62 FLJ90469, MGC4368 ENSG00000178927 Chromosome 17 open reading frame 62 17 82442589-82450829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045696 Uncertain Approved Plasma membrane
Cell Junctions Renal cancer:6.83e-11 (unfavourable) Expressed in all Expressed in all lymph node: 129.5 C17orf75 NJMU-R1 ENSG00000108666 Chromosome 17 open reading frame 75 17 32324565-32350023 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004061 Approved Approved Approved Golgi apparatus
Cytosol Renal cancer:1.33e-4 (favourable), Ovarian cancer:3.13e-4 (favourable) Expressed in all Expressed in all testis: 39.5 C17orf80 FLJ20721, HLC-8, MIG3, SPEP1 ENSG00000141219 Chromosome 17 open reading frame 80 17 73232233-73248947 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012896 Uncertain Approved Nucleoplasm
Vesicles Liver cancer:9.02e-6 (unfavourable), Colorectal cancer:1.43e-4 (favourable) Expressed in all Expressed in all testis: 71.6 C17orf89 ENSG00000224877 Chromosome 17 open reading frame 89 17 81239239-81241281 Predicted intracellular proteins Evidence at protein level HPA057732 Uncertain Approved Mitochondria Renal cancer:1.70e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 63.8 C18orf21 HsT3108, PNAS-124, PNAS-131 ENSG00000141428 Chromosome 18 open reading frame 21 18 35972083-35979286 Predicted intracellular proteins Evidence at protein level HPA065505, HPA067322 Uncertain Approved Nucleoli
Plasma membrane Liver cancer:1.38e-6 (unfavourable), Ovarian cancer:1.81e-6 (favourable) Expressed in all Expressed in all testis: 59.3 C18orf25 ARKL1, MGC12909, RNF111L1 ENSG00000152242 Chromosome 18 open reading frame 25 18 46173553-46266991 Predicted intracellular proteins Evidence at protein level HPA051314, HPA051899 Approved Approved Nucleoplasm
Cytosol Liver cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all esophagus: 39.0 C18orf32 FLJ23458 ENSG00000177576 Chromosome 18 open reading frame 32 18 49477250-49487252 Predicted membrane proteins Evidence at protein level HPA040921 Approved Approved Nucleoplasm
Vesicles Renal cancer:8.89e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 120.0 C18orf8 HsT2591, MIC-1, MIC1 ENSG00000141452 Chromosome 18 open reading frame 8 18 23503470-23531807 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043589 Uncertain Uncertain Nucleus Liver cancer:3.94e-4 (unfavourable) Expressed in all Expressed in all testis: 33.0 C19orf12 DKFZP762D096, MGC10922, NBIA4, SPG43 ENSG00000131943 Chromosome 19 open reading frame 12 19 29698886-29715789 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046930 Approved Expressed in all Expressed in all adipose tissue: 122.4 C19orf24 FLJ20640 ENSG00000228300 Chromosome 19 open reading frame 24 19 1275438-1279249 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043279, HPA047026 Uncertain Approved Nuclear speckles
Golgi apparatus Expressed in all Expressed in all appendix: 37.5 C19orf25 FLJ36666 ENSG00000119559 Chromosome 19 open reading frame 25 19 1461143-1479556 Predicted intracellular proteins Evidence at protein level HPA050270, HPA067491 Approved Approved Intermediate filaments Renal cancer:9.20e-8 (favourable), Endometrial cancer:1.08e-4 (favourable), Pancreatic cancer:1.21e-4 (favourable), Liver cancer:3.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 21.7 C19orf43 fSAP18, MGC2803 ENSG00000123144 Chromosome 19 open reading frame 43 19 12730640-12734775 Predicted intracellular proteins Evidence at protein level HPA059965 Approved Approved Nucleoplasm Expressed in all Expressed in all spleen: 127.8 C19orf47 FLJ36888 ENSG00000160392 Chromosome 19 open reading frame 47 19 40319536-40348527 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041843, HPA046309 Uncertain Validated Nucleoplasm Endometrial cancer:7.10e-5 (unfavourable), Liver cancer:1.41e-4 (unfavourable), Breast cancer:6.50e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 63.6 C19orf48 MGC13170 ENSG00000167747 Chromosome 19 open reading frame 48 19 50797704-50804929 Predicted intracellular proteins Evidence at transcript level HPA042000 Uncertain Approved Plasma membrane Liver cancer:8.80e-5 (unfavourable) Expressed in all Expressed in all prostate: 76.2 C19orf52 ENSG00000142444 Chromosome 19 open reading frame 52 19 10928733-10933535 Predicted intracellular proteins Evidence at protein level HPA041858 Approved Approved Nucleoplasm
Mitochondria Stomach cancer:7.03e-7 (favourable), Cervical cancer:9.93e-5 (favourable) Expressed in all Expressed in all cerebral cortex,duodenum: 7.6 C19orf53 HSPC023, LYDG10 ENSG00000104979 Chromosome 19 open reading frame 53 19 13774168-13778462 Predicted intracellular proteins Evidence at protein level HPA059928, HPA061291 Approved Supported Nucleus
Nucleoli Expressed in all Expressed in all fallopian tube: 115.6 C19orf54 FLJ41131 ENSG00000188493 Chromosome 19 open reading frame 54 19 40740856-40751553 Predicted intracellular proteins Evidence at protein level HPA059043, HPA059628 Approved Expressed in all Expressed in all parathyroid gland: 12.7 C19orf70 P117, QIL1 ENSG00000174917 Chromosome 19 open reading frame 70 19 5678421-5680896 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042672 Approved Supported Nucleoplasm
Mitochondria Renal cancer:7.60e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 75.3 C1D LRP1, Rrp47, SUN-CoR, SUNCOR ENSG00000197223 C1D nuclear receptor corepressor 2 68041130-68110948 Predicted intracellular proteins Evidence at protein level HPA037413, HPA037588 Approved Validated Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 51.7 C1GALT1 C1GALT, T-synthase ENSG00000106392 Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 7 7156934-7248651 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011294, HPA012819 Supported Approved Nuclear bodies
Cytosol Liver cancer:1.42e-5 (unfavourable), Cervical cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 93.3 C1GALT1C1 C1GALT2, COSMC ENSG00000171155 C1GALT1-specific chaperone 1 X 120625793-120630150 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015632 Approved Approved Cytosol Breast cancer:5.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 43.9 C1orf109 FLJ20508 ENSG00000116922 Chromosome 1 open reading frame 109 1 37681570-37692249 Predicted intracellular proteins Evidence at protein level HPA027110, HPA027127 Supported Approved Nucleus
Cytosol Liver cancer:1.76e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.7 C1orf122 FLJ45459 ENSG00000197982 Chromosome 1 open reading frame 122 1 37806979-37809454 Predicted intracellular proteins Evidence at protein level Urothelial cancer:4.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 52.9 C1orf123 FLJ20580 ENSG00000162384 Chromosome 1 open reading frame 123 1 53214099-53220617 Predicted intracellular proteins Evidence at protein level HPA043835 Uncertain Approved Cytosol Renal cancer:1.53e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 88.1 C1orf131 DKFZp547B1713 ENSG00000143633 Chromosome 1 open reading frame 131 1 231223763-231241187 Predicted intracellular proteins Evidence at protein level HPA028452, HPA029920 Approved Validated Nucleus
Nucleoli
Cytosol Renal cancer:2.64e-9 (unfavourable), Urothelial cancer:9.84e-4 (favourable) Expressed in all Expressed in all duodenum: 22.2 C1orf162 MGC24133 ENSG00000143110 Chromosome 1 open reading frame 162 1 111473792-111478512 Predicted membrane proteins Evidence at protein level HPA026988 Approved Renal cancer:3.14e-6 (unfavourable) Expressed in all Expressed in all spleen: 131.2 C1orf174 RP13-531C17.2 ENSG00000198912 Chromosome 1 open reading frame 174 1 3889125-3900293 Predicted intracellular proteins Evidence at protein level HPA008270, HPA065778 Approved Validated Nucleus Renal cancer:2.73e-6 (unfavourable), Liver cancer:5.84e-4 (unfavourable), Melanoma:7.62e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 17.3 C1orf198 DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710 ENSG00000119280 Chromosome 1 open reading frame 198 1 230837119-230869589 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004798 Approved Supported Cytosol Renal cancer:4.50e-5 (unfavourable) Expressed in all Expressed in all lung: 99.3 C1orf27 FLJ20505, odr-4, TTG1 ENSG00000157181 Chromosome 1 open reading frame 27 1 186375838-186421378 Predicted membrane proteins Evidence at protein level HPA015988, HPA031352 Uncertain Approved Nucleoplasm
Plasma membrane Ovarian cancer:9.92e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 75.0 C1orf35 MGC4174, MMTAG2 ENSG00000143793 Chromosome 1 open reading frame 35 1 228100726-228105411 Predicted intracellular proteins Evidence at protein level HPA046175 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Renal cancer:1.79e-6 (unfavourable), Ovarian cancer:7.38e-4 (favourable), Colorectal cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all skin: 14.3 C1orf43 DKFZp586G1722, NICE-3 ENSG00000143612 Chromosome 1 open reading frame 43 1 154206706-154220628 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010725 Approved Liver cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all kidney: 194.2 C1orf50 MGC955 ENSG00000164008 Chromosome 1 open reading frame 50 1 42767269-42794493 Predicted intracellular proteins Evidence at protein level HPA030236 Uncertain Melanoma:4.65e-4 (unfavourable) Expressed in all Expressed in all testis: 20.0 C1orf52 FLJ44982, gm117 ENSG00000162642 Chromosome 1 open reading frame 52 1 85249953-85259672 Predicted intracellular proteins Evidence at protein level HPA036072, HPA061790 Approved Validated Nucleus Renal cancer:1.17e-7 (unfavourable), Liver cancer:5.37e-5 (unfavourable), Prostate cancer:4.93e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 31.9 C1orf54 FLJ23221 ENSG00000118292 Chromosome 1 open reading frame 54 1 150268200-150280916 Predicted secreted proteins Evidence at transcript level HPA026518 Approved Approved Vesicles Renal cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all spleen: 77.4 C1QA ENSG00000173372 Complement component 1, q subcomponent, A chain 1 22636506-22639608 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002350, CAB009823 Supported Uncertain Golgi apparatus
Cytosol Renal cancer:1.58e-6 (unfavourable) Expressed in all Expressed in all spleen: 1187.9 C1QB ENSG00000173369 Complement component 1, q subcomponent, B chain 1 22652762-22661538 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA052116 Approved Renal cancer:9.58e-6 (unfavourable) Expressed in all Expressed in all spleen: 1460.4 C1QBP gC1Q-R, gC1qR, HABP1, p32, SF2p32 ENSG00000108561 Complement component 1, q subcomponent binding protein 17 5432777-5448830 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA026483 Supported Approved Plasma membrane
Mitochondria Expressed in all Expressed in all rectum: 159.4 C1QC C1QG ENSG00000159189 Complement component 1, q subcomponent, C chain 1 22643630-22648110 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001471, CAB009828 Supported Uncertain Vesicles Renal cancer:1.17e-5 (unfavourable) Expressed in all Expressed in all spleen: 1310.5 C1R ENSG00000159403 Complement component 1, r subcomponent 12 7080209-7092607 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001251, HPA001551 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.94e-14 (unfavourable) Expressed in all Expressed in all liver: 1216.5 C1RL C1r-LP, C1RL1 ENSG00000139178 Complement component 1, r subcomponent-like 12 7089587-7109273 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011338, CAB026172 Supported Approved Microtubules
Cytosol Renal cancer:1.52e-7 (unfavourable), Breast cancer:7.92e-4 (favourable) Expressed in all Expressed in all liver: 83.7 C1S ENSG00000182326 Complement component 1, s subcomponent 12 6988259-7071032 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016722, HPA018852 Supported Approved Nucleus
Cytosol Renal cancer:7.44e-15 (unfavourable), Liver cancer:7.73e-4 (favourable) Expressed in all Expressed in all liver: 1327.2 C20orf194 DKFZp434N061 ENSG00000088854 Chromosome 20 open reading frame 194 20 3249305-3407625 Predicted intracellular proteins Evidence at protein level HPA052103, HPA067418 Approved Approved Nucleoli fibrillar center
Mitochondria
Cytosol Pancreatic cancer:1.68e-4 (favourable), Renal cancer:7.68e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 26.5 C20orf24 PNAS-11, RIP5 ENSG00000101084 Chromosome 20 open reading frame 24 20 36605734-36612557 Predicted membrane proteins Evidence at protein level HPA057387 Uncertain Approved Cytosol Liver cancer:4.56e-6 (unfavourable), Renal cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all esophagus: 83.3 C20orf27 FLJ20550 ENSG00000101220 Chromosome 20 open reading frame 27 20 3753508-3768387 Predicted intracellular proteins Evidence at protein level HPA047483 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.18e-6 (unfavourable), Liver cancer:1.69e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 56.6 C20orf96 dJ1103G7.2 ENSG00000196476 Chromosome 20 open reading frame 96 20 270863-290778 Predicted intracellular proteins Evidence at transcript level HPA048649 Uncertain Approved Nucleus
Golgi apparatus Pancreatic cancer:4.12e-5 (favourable), Liver cancer:6.12e-5 (unfavourable), Urothelial cancer:1.05e-4 (favourable) Expressed in all Expressed in all fallopian tube: 52.9 C21orf2 A2, LRRC76, YF5 ENSG00000160226 Chromosome 21 open reading frame 2 21 44328944-44339402 Predicted intracellular proteins Evidence at protein level HPA030284, CAB034126, CAB034128 Supported Approved Nucleoplasm Pancreatic cancer:1.32e-4 (favourable), Renal cancer:4.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 18.0 C21orf33 D21S2048E, ES1, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI ENSG00000160221 Chromosome 21 open reading frame 33 21 44133605-44145723 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018517 Supported Mixed Expressed in all kidney: 35.3 C21orf59 C21orf48, CILD26, FBB18, FLJ20467 ENSG00000159079 Chromosome 21 open reading frame 59 21 32592079-32612866 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018453, HPA019055, HPA028849, CAB034170 Supported Supported Approved Rods & Rings Renal cancer:1.54e-5 (unfavourable), Endometrial cancer:8.90e-4 (favourable) Expressed in all Expressed in all testis: 78.2 C22orf39 MGC74441 ENSG00000242259 Chromosome 22 open reading frame 39 22 19351368-19448232 Predicted intracellular proteins Evidence at protein level HPA073701 Approved Endoplasmic reticulum Renal cancer:1.44e-4 (favourable), Endometrial cancer:2.16e-4 (favourable) Expressed in all Expressed in all thyroid gland: 51.9 C2CD2L KIAA0285, TMEM24 ENSG00000172375 C2CD2-like 11 119102198-119118544 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011044 Approved Approved Nucleus
Nuclear membrane
Nucleoli
Cytosol Renal cancer:1.75e-4 (unfavourable), Endometrial cancer:4.92e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.7 C2CD5 CDP138, KIAA0528 ENSG00000111731 C2 calcium-dependent domain containing 5 12 22448583-22544546 Predicted intracellular proteins Evidence at protein level HPA046194 Approved Approved Microtubule organizing center
Cytosol Expressed in all Expressed in all parathyroid gland: 50.8 C2orf47 DKFZp666A212, FLJ22555 ENSG00000162972 Chromosome 2 open reading frame 47 2 199955317-200008540 Predicted intracellular proteins Evidence at protein level HPA064013 Approved Mitochondria Melanoma:1.87e-4 (unfavourable), Endometrial cancer:2.14e-4 (unfavourable), Head and neck cancer:3.81e-4 (unfavourable) Expressed in all Expressed in all kidney: 31.7 C2orf49 asw, MGC5509 ENSG00000135974 Chromosome 2 open reading frame 49 2 105337359-105349211 Predicted intracellular proteins Evidence at protein level HPA043846, HPA060814 Approved Supported Nucleoplasm
Mitochondria Renal cancer:5.06e-5 (unfavourable) Expressed in all Expressed in all ovary: 24.2 C2orf68 ENSG00000168887 Chromosome 2 open reading frame 68 2 85606654-85612066 Predicted intracellular proteins Evidence at protein level HPA051143 Uncertain Approved Nucleus
Nuclear membrane
Nucleoli
Mitochondria Renal cancer:1.11e-6 (unfavourable), Endometrial cancer:1.12e-6 (unfavourable), Liver cancer:6.76e-6 (unfavourable) Expressed in all Expressed in all endometrium: 26.2 C2orf69 FLJ38973 ENSG00000178074 Chromosome 2 open reading frame 69 2 199911256-199955935 Predicted secreted proteins Evidence at protein level HPA045225 Uncertain Expressed in all Expressed in all testis: 26.5 C2orf74 LOC339804 ENSG00000237651 Chromosome 2 open reading frame 74 2 61145068-61164829 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA026826 Approved Approved Centrosome Mixed Expressed in all testis: 80.2 C2orf76 AIM29, LOC130355, MGC104437 ENSG00000186132 Chromosome 2 open reading frame 76 2 119302225-119366828 Predicted intracellular proteins Evidence at protein level HPA044977, HPA055362 Uncertain Approved Endoplasmic reticulum Renal cancer:2.16e-8 (unfavourable) Expressed in all Expressed in all epididymis: 52.2 C2orf88 MGC13057, smAKAP ENSG00000187699 Chromosome 2 open reading frame 88 2 189879609-190203484 Predicted intracellular proteins Evidence at protein level HPA049549 Approved Endometrial cancer:4.97e-4 (favourable), Renal cancer:7.79e-4 (favourable), Melanoma:9.39e-4 (unfavourable) Tissue enhanced Expressed in all testis: 92.3 C3 ARMD9, C3a, C3b, CPAMD1 ENSG00000125730 Complement component 3 19 6677704-6730562 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003563, CAB004209, HPA020432 Supported Renal cancer:1.09e-5 (unfavourable), Liver cancer:8.11e-4 (favourable) Expressed in all Expressed in all liver: 2484.3 C3orf17 DKFZP434F2021, NET17 ENSG00000163608 Chromosome 3 open reading frame 17 3 113002440-113019861 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069654 Supported Nucleus
Nucleoli Endometrial cancer:1.13e-4 (unfavourable), Liver cancer:4.25e-4 (unfavourable) Expressed in all Expressed in all testis: 21.7 C3orf38 MGC26717 ENSG00000179021 Chromosome 3 open reading frame 38 3 88149743-88168729 Predicted intracellular proteins Evidence at protein level HPA034736, HPA034737 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Ovarian cancer:3.55e-4 (favourable), Prostate cancer:4.12e-4 (unfavourable) Expressed in all Expressed in all testis: 58.7 C4orf27 FLJ20534 ENSG00000056050 Chromosome 4 open reading frame 27 4 169729465-169757953 Predicted intracellular proteins Evidence at protein level HPA043467 Uncertain Approved Microtubules
Cytokinetic bridge
Cytosol Melanoma:5.63e-4 (unfavourable), Ovarian cancer:7.47e-4 (favourable) Expressed in all Expressed in all endometrium: 38.3 C4orf3 ENSG00000164096 Chromosome 4 open reading frame 3 4 119296419-119304445 Predicted membrane proteins Evidence at protein level HPA026907 Approved Approved Cytosol Renal cancer:3.46e-4 (favourable) Expressed in all Expressed in all esophagus: 151.2 C4orf33 FLJ33703 ENSG00000151470 Chromosome 4 open reading frame 33 4 129093317-129116640 Predicted intracellular proteins Evidence at protein level HPA061199 Uncertain Approved Nuclear bodies
Golgi apparatus Urothelial cancer:2.49e-5 (favourable), Renal cancer:3.04e-4 (favourable) Expressed in all Expressed in all thyroid gland: 28.1 C5orf15 HTGN29, KCT2 ENSG00000113583 Chromosome 5 open reading frame 15 5 133955502-133968787 Predicted membrane proteins Evidence at protein level HPA011951, HPA039165 Uncertain Approved Golgi apparatus Expressed in all Expressed in all thyroid gland: 81.4 C5orf22 FLJ11193 ENSG00000082213 Chromosome 5 open reading frame 22 5 31532266-31555058 Predicted intracellular proteins Evidence at protein level HPA043062 Approved Approved Nuclear membrane Liver cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 13.4 C5orf24 FLJ37562 ENSG00000181904 Chromosome 5 open reading frame 24 5 134845680-134859737 Predicted intracellular proteins Evidence at protein level HPA057749, HPA062502 Uncertain Supported Nucleus Renal cancer:5.86e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.6 C5orf28 FLJ21657 ENSG00000151881 Chromosome 5 open reading frame 28 5 43444252-43483893 Predicted membrane proteins Evidence at protein level HPA059946 Approved Nucleoplasm Liver cancer:1.59e-4 (unfavourable), Renal cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 64.8 C5orf51 LOC285636 ENSG00000205765 Chromosome 5 open reading frame 51 5 41904188-41921636 Predicted intracellular proteins Evidence at protein level HPA043779, HPA063816 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 26.6 C6orf1 LBH, MGC57858 ENSG00000186577 Chromosome 6 open reading frame 1 6 34246380-34249470 Predicted intracellular proteins Evidence at transcript level HPA037659, HPA037660 Uncertain Renal cancer:4.38e-4 (unfavourable), Pancreatic cancer:7.98e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 70.1 C6orf106 dJ391O22.4, FLJ22195 ENSG00000196821 Chromosome 6 open reading frame 106 6 34587288-34696859 Predicted intracellular proteins Evidence at protein level HPA034489, HPA034490 Approved Approved Nuclear speckles Expressed in all Expressed in all testis: 125.3 C6orf120 bA160E12.4 ENSG00000185127 Chromosome 6 open reading frame 120 6 169702190-169704856 Predicted secreted proteins Evidence at protein level HPA039626 Uncertain Liver cancer:9.52e-5 (unfavourable), Cervical cancer:2.26e-4 (unfavourable), Ovarian cancer:8.37e-4 (unfavourable) Expressed in all Expressed in all placenta: 28.7 C6orf203 HSPC230, PRED31 ENSG00000130349 Chromosome 6 open reading frame 203 6 107028213-107051342 Predicted intracellular proteins Evidence at protein level HPA049535 Approved Urothelial cancer:2.11e-5 (favourable), Renal cancer:4.09e-5 (favourable), Pancreatic cancer:3.29e-4 (favourable) Expressed in all Expressed in all adrenal gland: 47.8 C6orf226 LOC441150 ENSG00000221821 Chromosome 6 open reading frame 226 6 42890265-42890816 Predicted intracellular proteins Evidence at protein level HPA045350 Approved Approved Nuclear speckles Breast cancer:1.93e-5 (favourable), Renal cancer:3.35e-4 (favourable), Pancreatic cancer:5.13e-4 (favourable) Expressed in all Expressed in all adrenal gland: 13.4 C6orf48 D6S57, G8 ENSG00000204387 Chromosome 6 open reading frame 48 6 31834608-31839766 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all ovary: 110.5 C6orf62 DKFZP564G182, FLJ12619, XTP12 ENSG00000112308 Chromosome 6 open reading frame 62 6 24704861-24720836 Predicted intracellular proteins Evidence at protein level HPA030564, HPA030566 Supported Approved Cytosol Urothelial cancer:3.62e-6 (favourable), Liver cancer:5.77e-5 (unfavourable), Ovarian cancer:4.04e-4 (favourable) Expressed in all Expressed in all testis: 173.7 C6orf89 BRAP, FLJ25357 ENSG00000198663 Chromosome 6 open reading frame 89 6 36871870-36928964 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012548 Uncertain Renal cancer:5.77e-5 (favourable) Expressed in all Expressed in all thyroid gland: 96.8 C7orf26 MGC2718 ENSG00000146576 Chromosome 7 open reading frame 26 7 6590017-6608726 Predicted intracellular proteins Evidence at protein level HPA042899, HPA052175 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments
Cytosol Pancreatic cancer:6.95e-5 (favourable) Expressed in all Expressed in all spleen: 26.2 C7orf43 FLJ10925 ENSG00000146826 Chromosome 7 open reading frame 43 7 100154420-100158715 Predicted intracellular proteins Evidence at protein level HPA019359, HPA029463, HPA029464 Approved Validated Vesicles
Plasma membrane
Microtubule organizing center Pancreatic cancer:6.19e-5 (favourable) Expressed in all Expressed in all testis: 33.4 C7orf49 FLJ22450, FLJ27285, MGC5242, MRI ENSG00000122783 Chromosome 7 open reading frame 49 7 135092363-135170795 Predicted intracellular proteins Evidence at protein level HPA020060 Approved Approved Golgi apparatus Liver cancer:2.52e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.8 C7orf50 MGC11257, YCR016W ENSG00000146540 Chromosome 7 open reading frame 50 7 996986-1138260 Predicted intracellular proteins Evidence at protein level HPA052281 Approved Approved Nucleus
Nucleoli Pancreatic cancer:6.20e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 56.0 C7orf55 FMC1, HSPC268 ENSG00000164898 Chromosome 7 open reading frame 55 7 139339457-139346319 Predicted intracellular proteins Evidence at protein level HPA045663, HPA050553 Approved Approved Mitochondria Ovarian cancer:5.63e-6 (favourable), Renal cancer:2.05e-5 (favourable), Lung cancer:1.08e-4 (favourable) Expressed in all Expressed in all thyroid gland: 12.2 C7orf55-LUC7L2 ENSG00000269955 C7orf55-LUC7L2 readthrough 7 139341360-139422599 Predicted intracellular proteins Evidence at protein level HPA045663, HPA051631 Approved Approved Nucleus Not detected Expressed in all skeletal muscle: 21.0 C7orf73 PL-5283 ENSG00000243317 Chromosome 7 open reading frame 73 7 135662496-135693418 Predicted secreted proteins Evidence at protein level HPA065565 Approved Mitochondria Ovarian cancer:2.95e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.2 C8orf33 FLJ20989 ENSG00000182307 Chromosome 8 open reading frame 33 8 145052378-145056030 Predicted intracellular proteins Evidence at protein level HPA024812, HPA026104 Approved Uncertain Nucleoplasm
Plasma membrane Breast cancer:2.77e-4 (unfavourable), Liver cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.8 C8orf59 ENSG00000176731 Chromosome 8 open reading frame 59 8 85214076-85220421 Predicted intracellular proteins Evidence at protein level HPA044805, HPA071903 Approved Nucleus
Nucleoli
Cytosol Renal cancer:0.00e+0 (unfavourable) Expressed in all Expressed in all breast: 119.7 C8orf76 FLJ14825 ENSG00000189376 Chromosome 8 open reading frame 76 8 123219957-123241398 Predicted intracellular proteins Evidence at transcript level HPA023708 Uncertain Uncertain Nucleoplasm
Cytosol Renal cancer:5.95e-11 (unfavourable), Endometrial cancer:1.61e-4 (unfavourable), Breast cancer:9.95e-4 (unfavourable) Expressed in all Expressed in all placenta: 16.0 C8orf82 MGC70857 ENSG00000213563 Chromosome 8 open reading frame 82 8 144525733-144529132 Predicted intracellular proteins Evidence at protein level CAB034331 Uncertain Approved Nucleus Renal cancer:1.70e-5 (favourable) Expressed in all Expressed in all prostate: 29.9 C9orf114 CENP-32, HSPC109 ENSG00000198917 Chromosome 9 open reading frame 114 9 128819651-128829821 Predicted intracellular proteins Evidence at protein level HPA022990 Approved Nucleus
Nucleoli Pancreatic cancer:4.09e-4 (favourable) Expressed in all Expressed in all lymph node: 22.3 C9orf142 PAXX ENSG00000148362 Chromosome 9 open reading frame 142 9 136992418-136993984 Predicted intracellular proteins Evidence at protein level HPA045268 Uncertain Supported Nucleus Cervical cancer:2.06e-4 (favourable), Pancreatic cancer:6.71e-4 (favourable) Expressed in all Expressed in all spleen: 22.3 C9orf16 EST00098, FLJ12823, MGC4639 ENSG00000171159 Chromosome 9 open reading frame 16 9 128160260-128163928 Predicted intracellular proteins Evidence at protein level HPA020725 Uncertain Approved Microtubules Liver cancer:3.13e-5 (unfavourable), Cervical cancer:7.60e-4 (favourable), Colorectal cancer:9.91e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 152.1 C9orf3 AOPEP, AP-O, APO, C90RF3, FLJ14675 ENSG00000148120 Chromosome 9 open reading frame 3 9 94726701-95087218 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004633, HPA072729 Approved Approved Cell Junctions Renal cancer:6.33e-5 (favourable) Expressed in all Expressed in all skin: 50.1 C9orf64 MGC10999 ENSG00000165118 Chromosome 9 open reading frame 64 9 83938311-83956986 Predicted intracellular proteins Evidence at protein level HPA054903, HPA066190 Uncertain Approved Golgi apparatus Renal cancer:4.23e-4 (favourable) Expressed in all Expressed in all thyroid gland: 27.3 C9orf69 bA83N9.1 ENSG00000238227 Chromosome 9 open reading frame 69 9 136114581-136118863 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066070 Supported Supported Nucleoplasm Endometrial cancer:1.09e-4 (favourable) Expressed in all Expressed in all skin: 23.8 C9orf72 MGC23980 ENSG00000147894 Chromosome 9 open reading frame 72 9 27546545-27573866 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023873 Uncertain Expressed in all Expressed in all testis: 32.0 C9orf78 HCA59, HSPC220 ENSG00000136819 Chromosome 9 open reading frame 78 9 129827290-129835863 Predicted intracellular proteins Evidence at protein level HPA021216, HPA021232, HPA021242 Supported Validated Nucleoplasm Renal cancer:3.49e-7 (favourable) Expressed in all Expressed in all bone marrow: 71.4 C9orf85 MGC61599 ENSG00000155621 Chromosome 9 open reading frame 85 9 71911510-71986054 Predicted intracellular proteins Evidence at protein level HPA050767 Approved Nucleus
Nucleoli
Golgi apparatus Expressed in all Expressed in all thyroid gland: 13.9 C9orf91 DKFZp547P234, FLJ38045 ENSG00000157693 Chromosome 9 open reading frame 91 9 114611206-114646422 Predicted membrane proteins Evidence at transcript level HPA017199 Approved Approved Plasma membrane
Cytosol Endometrial cancer:3.61e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.4 CAAP1 C9orf82, CAAP, FLJ13657 ENSG00000120159 Caspase activity and apoptosis inhibitor 1 9 26840685-26892804 Predicted intracellular proteins Evidence at protein level HPA020404, HPA024029, HPA024100 Uncertain Approved Vesicles Renal cancer:7.94e-9 (favourable), Ovarian cancer:1.27e-5 (favourable) Expressed in all Expressed in all thyroid gland: 49.4 CAB39 CGI-66, MO25 ENSG00000135932 Calcium binding protein 39 2 230712845-230821075 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037112 Supported Approved Nucleoli
Cytosol Renal cancer:9.05e-6 (favourable), Pancreatic cancer:8.33e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 79.1 CAB39L bA103J18.3, FLJ12577, MO2L ENSG00000102547 Calcium binding protein 39-like 13 49308650-49444126 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003686, HPA045954 Uncertain Approved Vesicles Renal cancer:1.94e-13 (favourable), Ovarian cancer:2.28e-4 (unfavourable), Prostate cancer:7.91e-4 (favourable) Expressed in all Expressed in all prostate: 64.2 CABIN1 KIAA0330, PPP3IN ENSG00000099991 Calcineurin binding protein 1 22 24011192-24178628 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043296 Approved Approved Nucleoplasm
Aggresome
Cytosol Endometrial cancer:9.57e-5 (favourable), Renal cancer:2.94e-4 (favourable) Expressed in all Expressed in all thyroid gland: 33.7 CACFD1 C9orf7, D9S2135, flower ENSG00000160325 Calcium channel flower domain containing 1 9 133459965-133470848 Predicted membrane proteins, Transporters Evidence at protein level HPA015280 Approved Nucleoplasm Renal cancer:2.83e-8 (favourable) Expressed in all Expressed in all thyroid gland: 16.6 CACTIN C19orf29, cactin, fSAPc, NY-REN-24 ENSG00000105298 Cactin, spliceosome C complex subunit 19 3610641-3626815 Predicted intracellular proteins Evidence at protein level HPA042504, HPA042548 Approved Supported Nucleoplasm
Nuclear speckles
Cytosol Endometrial cancer:3.69e-5 (favourable) Expressed in all Expressed in all spleen: 14.7 CACUL1 C10orf46, CAC1, FLJ40409, MGC33215 ENSG00000151893 CDK2-associated, cullin domain 1 10 118674167-118755249 Predicted intracellular proteins Evidence at protein level HPA050611 Uncertain Nucleoplasm Liver cancer:1.34e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland,testis: 12.0 CACYBP S100A6BP, SIP ENSG00000116161 Calcyclin binding protein 1 174999163-175011715 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025753, HPA057038 Approved Validated Nucleoplasm
Cytosol Liver cancer:1.12e-6 (unfavourable), Ovarian cancer:1.39e-5 (favourable), Renal cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 60.9 CAD ENSG00000084774 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 2 27217390-27243943 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB007781, HPA057266, HPA069341 Supported Supported Nucleoplasm Liver cancer:1.72e-11 (unfavourable), Renal cancer:1.82e-4 (unfavourable) Expressed in all Expressed in all skin: 22.0 CALCOCO1 calphoglin, Cocoa, KIAA1536 ENSG00000012822 Calcium binding and coiled-coil domain 1 12 53708517-53727745 Predicted intracellular proteins Evidence at protein level HPA038313, HPA038314 Approved Validated Cytosol Expressed in all Expressed in all skin: 161.0 CALCOCO2 MGC17318, NDP52 ENSG00000136436 Calcium binding and coiled-coil domain 2 17 48830988-48866522 Predicted intracellular proteins Evidence at protein level HPA022989, HPA023019, HPA023195 Supported Supported Vesicles
Cytosol Expressed in all Expressed in all testis: 247.8 CALM1 CALML2, CAMI, DD132, PHKD ENSG00000198668 Calmodulin 1 (phosphorylase kinase, delta) 14 90396502-90408261 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level CAB018558, HPA044999 Supported Approved Vesicles Urothelial cancer:2.38e-5 (unfavourable), Pancreatic cancer:5.62e-4 (favourable), Renal cancer:6.49e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1329.9 CALM2 CAMII, PHKD ENSG00000143933 Calmodulin 2 (phosphorylase kinase, delta) 2 47160082-47176601 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level CAB007790, HPA044999 Approved Thyroid cancer:1.94e-5 (favourable), Liver cancer:8.35e-5 (unfavourable), Endometrial cancer:4.84e-4 (unfavourable), Breast cancer:5.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1537.9 CALM3 PHKD ENSG00000160014 Calmodulin 3 (phosphorylase kinase, delta) 19 46601074-46610793 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level HPA044999 Approved Lung cancer:2.07e-4 (unfavourable), Thyroid cancer:9.10e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1317.4 CALR cC1qR, CRT, FLJ26680, RO, SSA ENSG00000179218 Calreticulin 19 12938578-12944489 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB001513, HPA002242, CAB019952 Supported Renal cancer:1.11e-16 (unfavourable), Ovarian cancer:1.10e-4 (favourable) Expressed in all Expressed in all thyroid gland: 1647.1 CALU ENSG00000128595 Calumenin 7 128739292-128771807 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006018 Supported Supported Endoplasmic reticulum Renal cancer:1.30e-11 (unfavourable), Urothelial cancer:4.60e-5 (unfavourable), Liver cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 439.7 CAMK1 CaMKI ENSG00000134072 Calcium/calmodulin-dependent protein kinase I 3 9757342-9769992 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB031904, HPA051409 Approved Approved Cytosol Liver cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 108.1 CAMK2D CAMKD ENSG00000145349 Calcium/calmodulin-dependent protein kinase II delta 4 113451032-113761927 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026281, HPA051783, HPA051785, HPA053973 Approved Supported Plasma membrane
Cell Junctions Expressed in all Expressed in all parathyroid gland: 106.2 CAMK2G CAMKG ENSG00000148660 Calcium/calmodulin-dependent protein kinase II gamma 10 73812501-73874591 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040656, HPA051783, HPA051785, HPA053973 Approved Approved Plasma membrane
Cell Junctions
Cytosol Expressed in all Expressed in all cerebral cortex: 119.4 CAMKK2 CAMKK, CAMKKB, KIAA0787, MGC15254 ENSG00000110931 Calcium/calmodulin-dependent protein kinase kinase 2, beta 12 121237691-121298308 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017389 Approved Supported Cytosol Expressed in all Expressed in all cerebral cortex: 103.1 CAMKMT C2orf34, CLNMT ENSG00000143919 Calmodulin-lysine N-methyltransferase 2 44361950-44772592 Enzymes, Predicted intracellular proteins Evidence at protein level HPA067912 Supported Nucleus Glioma:5.39e-4 (favourable) Expressed in all Expressed in all testis: 24.4 CAMLG CAML, GET2 ENSG00000164615 Calcium modulating ligand 5 134738501-134752160 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA052636, HPA056472 Approved Approved Nucleus
Nucleoli
Vesicles Renal cancer:1.09e-5 (unfavourable) Expressed in all Expressed in all testis: 99.0 CAMSAP1 DKFZp434F195, FLJ31228 ENSG00000130559 Calmodulin regulated spectrin-associated protein 1 9 135808487-135907228 Predicted intracellular proteins Evidence at protein level HPA020527, HPA024161 Approved Supported Mitotic spindle
Cytosol Renal cancer:3.09e-5 (favourable) Expressed in all Expressed in all testis: 34.2 CAMTA1 KIAA0833 ENSG00000171735 Calmodulin binding transcription activator 1 1 6785324-7769706 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036342, HPA036343 Approved Supported Nucleoli
Cytosol Ovarian cancer:4.10e-4 (favourable), Liver cancer:5.25e-4 (unfavourable) Expressed in all Expressed in all epididymis: 98.1 CAMTA2 KIAA0909 ENSG00000108509 Calmodulin binding transcription activator 2 17 4967992-4987652 Predicted intracellular proteins Evidence at protein level HPA051147 Approved Nucleus
Actin filaments
Mitochondria Pancreatic cancer:6.00e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 40.6 CAND1 DKFZp434M1414, KIAA0829, TIP120, TIP120A ENSG00000111530 Cullin-associated and neddylation-dissociated 1 12 67269281-67319951 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA055748, HPA062833, HPA069053 Approved Validated Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:1.15e-4 (unfavourable) Expressed in all Expressed in all testis: 50.9 CANT1 SCAN-1, SHAPY ENSG00000171302 Calcium activated nucleotidase 1 17 78991717-79009867 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019627, HPA019639, HPA022818 Supported Liver cancer:1.41e-4 (unfavourable), Lung cancer:2.90e-4 (unfavourable), Renal cancer:6.21e-4 (unfavourable) Expressed in all Expressed in all prostate: 110.0 CANX CNX, IP90, P90 ENSG00000127022 Calnexin 5 179678628-179730925 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004738, HPA009433, HPA009696 Supported Validated Endoplasmic reticulum Colorectal cancer:1.38e-4 (favourable), Thyroid cancer:3.17e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 871.4 CAP1 CAP ENSG00000131236 CAP, adenylate cyclase-associated protein 1 (yeast) 1 40040233-40072649 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030124 Approved Supported Cytosol Liver cancer:1.44e-6 (unfavourable) Expressed in all Expressed in all appendix: 429.7 CAPG AFCP, MCP ENSG00000042493 Capping protein (actin filament), gelsolin-like 2 85394748-85418432 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018843, HPA019080, HPA019092 Supported Validated Nucleus Liver cancer:3.22e-5 (unfavourable), Renal cancer:2.96e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 233.4 CAPN1 CANP, CANPL1, muCANP, muCL ENSG00000014216 Calpain 1, (mu/I) large subunit 11 65180566-65212006 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005992 Supported Supported Cytosol Renal cancer:7.06e-8 (favourable), Pancreatic cancer:4.30e-4 (unfavourable) Expressed in all Expressed in all esophagus: 245.3 CAPN10 ENSG00000142330 Calpain 10 2 240586716-240617705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004170, HPA056098 Approved Approved Nucleoplasm
Cytosol Liver cancer:4.78e-6 (unfavourable), Pancreatic cancer:7.94e-5 (favourable), Head and neck cancer:8.47e-5 (favourable) Expressed in all Expressed in all spleen: 15.5 CAPN2 CANPL2, CANPml, mCANP ENSG00000162909 Calpain 2, (m/II) large subunit 1 223701593-223776018 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024470 Approved Supported Cytosol Renal cancer:2.19e-4 (favourable), Pancreatic cancer:2.50e-4 (unfavourable), Urothelial cancer:6.21e-4 (unfavourable) Expressed in all Expressed in all lung: 267.2 CAPN3 CANP3, LGMD2, LGMD2A, nCL-1, p94 ENSG00000092529 Calpain 3 15 42359500-42412318 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040052 Approved Tissue enriched Expressed in all skeletal muscle: 357.7 CAPN7 PalBH ENSG00000131375 Calpain 7 3 15206152-15252918 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046617 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Colorectal cancer:4.85e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.2 CAPNS1 30K, CANP, CANPS, CAPN4, CDPS ENSG00000126247 Calpain, small subunit 1 19 36139575-36150353 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006872 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all esophagus: 517.3 CAPRIN1 caprin-1, GPIAP1, M11S1, RNG105 ENSG00000135387 Cell cycle associated protein 1 11 34051683-34101156 Predicted intracellular proteins Evidence at protein level HPA018126, HPA063617 Approved Validated Cytosol Liver cancer:8.67e-8 (unfavourable) Expressed in all Expressed in all testis: 248.2 CAPZA1 ENSG00000116489 Capping protein (actin filament) muscle Z-line, alpha 1 1 112619173-112671619 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB045963 Approved Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.54e-6 (unfavourable) Expressed in all Expressed in all lymph node: 135.8 CAPZA2 CAPPA2, CAPZ ENSG00000198898 Capping protein (actin filament) muscle Z-line, alpha 2 7 116811070-116922049 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007470, HPA007643 Uncertain Approved Endoplasmic reticulum
Cytosol Renal cancer:3.65e-6 (favourable), Liver cancer:9.34e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 41.9 CAPZB ENSG00000077549 Capping protein (actin filament) muscle Z-line, beta 1 19338776-19485539 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031531, HPA056066 Approved Validated Nucleoplasm
Vesicles
Cytosol Liver cancer:1.85e-4 (unfavourable), Renal cancer:3.57e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 484.4 CARD16 COP, COP1, PSEUDO-ICE ENSG00000204397 Caspase recruitment domain family, member 16 11 105041326-105101431 Predicted intracellular proteins Evidence at protein level HPA053981, HPA062805 Uncertain Approved Mitochondria Renal cancer:6.93e-7 (unfavourable) Expressed in all Expressed in all spleen: 161.8 CARD8 CARDINAL, Dakar, KIAA0955, NDPP, TUCAN ENSG00000105483 Caspase recruitment domain family, member 8 19 48180770-48255946 Predicted intracellular proteins Evidence at protein level HPA042071, HPA043513 Supported Validated Nucleoplasm
Cytosol Renal cancer:1.63e-8 (unfavourable), Urothelial cancer:1.72e-5 (favourable) Expressed in all Expressed in all spleen: 50.8 CARHSP1 CRHSP-24, CSDC1 ENSG00000153048 Calcium regulated heat stable protein 1, 24kDa 16 8852942-8869012 Predicted intracellular proteins Evidence at protein level HPA051911 Approved Urothelial cancer:7.24e-4 (favourable) Expressed in all Expressed in all testis: 261.5 CARKD FLJ10769, LP3298 ENSG00000213995 Carbohydrate kinase domain containing 13 110615460-110639993 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010551 Uncertain Renal cancer:4.63e-5 (favourable), Endometrial cancer:3.15e-4 (favourable) Expressed in all Expressed in all adrenal gland,seminal vesicle: 27.0 CARM1 PRMT4 ENSG00000142453 Coactivator-associated arginine methyltransferase 1 19 10871513-10923070 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB032961, HPA043561, HPA048073 Supported Validated Nucleoplasm Renal cancer:7.88e-6 (unfavourable), Urothelial cancer:8.37e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 37.1 CARNMT1 C9orf41, FLJ25795 ENSG00000156017 Carnosine N-methyltransferase 1 9 74981020-75028423 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026756 Uncertain Expressed in all Expressed in all testis: 29.9 CARS CARS1 ENSG00000110619 Cysteinyl-tRNA synthetase 11 3000922-3057613 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737 Supported Validated Cytosol Renal cancer:0.00e+0 (unfavourable), Liver cancer:5.16e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.2 CARS2 FLJ12118 ENSG00000134905 Cysteinyl-tRNA synthetase 2, mitochondrial (putative) 13 110641412-110713603 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041776 Uncertain Approved Nucleoplasm
Mitochondria Renal cancer:2.49e-5 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Endometrial cancer:1.84e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 28.3 CASC3 BTZ, MLN51 ENSG00000108349 Cancer susceptibility candidate 3 17 40140318-40172183 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level HPA024592, HPA050262 Approved Approved Nuclear membrane Expressed in all Expressed in all testis: 94.9 CASC4 DKFZp459F1927, H63 ENSG00000166734 Cancer susceptibility candidate 4 15 44288729-44415758 Predicted intracellular proteins Evidence at protein level HPA043015, HPA049488 Approved Supported Golgi apparatus Renal cancer:1.45e-5 (favourable) Expressed in all Expressed in all thyroid gland: 141.1 CASD1 C7orf12, FLJ21213, FLJ21879 ENSG00000127995 CAS1 domain containing 1 7 94509219-94557019 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044404 Uncertain Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 38.9 CASK CAGH39, FGS4, LIN2, TNRC8 ENSG00000147044 Calcium/calmodulin-dependent serine protein kinase (MAGUK family) X 41514934-41923463 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB001949, HPA023857 Supported Approved Nucleoplasm
Cytosol Pancreatic cancer:6.11e-5 (unfavourable) Expressed in all Expressed in all small intestine: 35.2 CASP2 ICH1, MGC2181, NEDD2, PPP1R57 ENSG00000106144 Caspase 2, apoptosis-related cysteine peptidase 7 143288215-143307696 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012175, HPA050678 Approved Approved Nucleoplasm Renal cancer:5.01e-6 (unfavourable), Liver cancer:2.34e-4 (unfavourable), Ovarian cancer:2.89e-4 (favourable), Cervical cancer:7.38e-4 (favourable) Expressed in all Expressed in all lymph node: 25.3 CASP3 apopain, CPP32, CPP32B, Yama ENSG00000164305 Caspase 3, apoptosis-related cysteine peptidase 4 184627696-184649509 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000091, HPA002643, CAB008381 Approved Supported Nucleoplasm
Mitochondria Renal cancer:2.30e-5 (unfavourable), Endometrial cancer:2.24e-4 (favourable) Expressed in all Expressed in all duodenum: 55.9 CASP4 ICE(rel)II, ICH-2, TX ENSG00000196954 Caspase 4, apoptosis-related cysteine peptidase 11 104942866-104969436 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA027588, CAB037167 Approved Approved Plasma membrane
Cytosol Renal cancer:3.27e-11 (unfavourable) Expressed in all Expressed in all placenta: 71.5 CASP6 MCH2 ENSG00000138794 Caspase 6, apoptosis-related cysteine peptidase 4 109688622-109703583 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB003775, HPA011337, HPA024303 Supported Supported Nucleus
Cytosol Colorectal cancer:2.64e-5 (favourable), Urothelial cancer:9.93e-4 (favourable) Expressed in all Expressed in all small intestine: 47.1 CASP7 CMH-1, ICE-LAP3, MCH3 ENSG00000165806 Caspase 7, apoptosis-related cysteine peptidase 10 113679162-113730907 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB025563 Approved Breast cancer:2.11e-4 (favourable), Renal cancer:5.90e-4 (unfavourable) Expressed in all Expressed in all small intestine: 75.9 CASP8 Casp-8, FLICE, MACH, MCH5 ENSG00000064012 Caspase 8, apoptosis-related cysteine peptidase 2 201233443-201287711 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001302, CAB002047, HPA005688, HPA006191 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.27e-6 (unfavourable), Ovarian cancer:1.25e-4 (favourable), Liver cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 45.6 CASP9 APAF-3, ICE-LAP6, MCH6, PPP1R56 ENSG00000132906 Caspase 9, apoptosis-related cysteine peptidase 1 15490832-15526534 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA001473, CAB004348, HPA046488 Approved Approved Mitochondria Urothelial cancer:1.67e-5 (favourable), Breast cancer:5.91e-4 (favourable) Expressed in all Expressed in all adrenal gland: 37.3 CAST ENSG00000153113 Calpastatin 5 96525267-96779595 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009491, HPA036881, HPA036882 Approved Validated Endoplasmic reticulum
Cytosol Stomach cancer:1.20e-5 (unfavourable), Pancreatic cancer:9.27e-5 (unfavourable), Urothelial cancer:4.98e-4 (unfavourable) Expressed in all Expressed in all esophagus: 403.4 CAT ENSG00000121691 Catalase 11 34438925-34472062 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001515, HPA051282, HPA055838 Supported Supported Vesicles
Cytosol Renal cancer:1.96e-8 (favourable), Liver cancer:9.67e-4 (favourable) Expressed in all Expressed in all liver: 624.4 CBFA2T2 MTGR1, ZMYND3 ENSG00000078699 Core-binding factor, runt domain, alpha subunit 2; translocated to, 2 20 33490075-33650036 Predicted intracellular proteins Evidence at protein level HPA060523, HPA072433 Supported Approved Nuclear speckles Pancreatic cancer:6.93e-6 (favourable) Expressed in all Expressed in all prostate: 23.0 CBFB PEBP2B ENSG00000067955 Core-binding factor, beta subunit 16 67029116-67101058 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038852 Uncertain Approved Nucleus
Cytosol Renal cancer:2.89e-8 (unfavourable), Liver cancer:2.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 95.6 CBLB Cbl-b, RNF56 ENSG00000114423 Cbl proto-oncogene B, E3 ubiquitin protein ligase 3 105655461-105869552 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA018327, HPA019880 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all lymph node: 28.4 CBLL1 FLJ23109, HAKAI, RNF188 ENSG00000105879 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 7 107743697-107761667 Predicted intracellular proteins Evidence at protein level HPA021773, HPA026699 Supported Supported Nuclear speckles Expressed in all Expressed in all testis: 36.0 CBR1 CBR, SDR21C1 ENSG00000159228 Carbonyl reductase 1 21 36069941-36073166 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018433 Approved Approved Nucleus
Cytosol Breast cancer:2.18e-4 (favourable), Renal cancer:4.75e-4 (favourable) Expressed in all Expressed in all duodenum: 560.1 CBR4 FLJ14431, SDR45C1 ENSG00000145439 Carbonyl reductase 4 4 168863770-169010275 Predicted intracellular proteins Evidence at protein level HPA037499 Supported Renal cancer:3.64e-14 (favourable) Expressed in all Expressed in all kidney: 28.6 CBWD1 ENSG00000172785 COBW domain containing 1 9 121038-179147 Predicted intracellular proteins Evidence at protein level HPA042759, HPA042813 Approved Approved Plasma membrane Mixed Expressed in all adrenal gland: 45.0 CBWD3 bA561O23.1 ENSG00000196873 COBW domain containing 3 9 68232003-68300015 Predicted intracellular proteins Evidence at transcript level HPA042759, HPA042813 Uncertain Approved Plasma membrane Not detected Expressed in all appendix: 25.9 CBWD5 ENSG00000147996 COBW domain containing 5 9 65668805-65734041 Predicted intracellular proteins Evidence at transcript level HPA042759, HPA042813 Approved Approved Plasma membrane Mixed Expressed in all breast: 21.6 CBX1 CBX, HP1-BETA, HP1Hs-beta, M31, MOD1 ENSG00000108468 Chromobox homolog 1 17 48070052-48101521 Predicted intracellular proteins Evidence at protein level CAB012265 Supported Supported Nucleus
Nuclear bodies Liver cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all testis: 125.1 CBX3 HP1Hs-gamma ENSG00000122565 Chromobox homolog 3 7 26201162-26213356 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001973, HPA004902 Supported Supported Nucleus
Nuclear bodies Liver cancer:2.20e-8 (unfavourable), Renal cancer:4.56e-7 (unfavourable), Pancreatic cancer:4.00e-4 (unfavourable), Breast cancer:7.92e-4 (unfavourable) Expressed in all Expressed in all testis: 203.5 CBX5 HP1, HP1-ALPHA, HP1Hs-alpha ENSG00000094916 Chromobox homolog 5 12 54230940-54280133 Predicted intracellular proteins Evidence at protein level HPA016699, CAB017548 Supported Validated Nucleus Expressed in all Expressed in all parathyroid gland: 57.3 CBX6 ENSG00000183741 Chromobox homolog 6 22 38861450-38872314 Predicted intracellular proteins Evidence at protein level HPA048653 Uncertain Approved Nucleus
Mitochondria Pancreatic cancer:2.46e-6 (favourable), Liver cancer:8.30e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 103.9 CBX7 ENSG00000100307 Chromobox homolog 7 22 39120167-39152674 Predicted intracellular proteins Evidence at protein level CAB011574, HPA048677, HPA056480 Supported Supported Nucleoplasm
Cytosol Renal cancer:2.45e-5 (favourable), Pancreatic cancer:1.04e-4 (favourable), Cervical cancer:3.63e-4 (favourable), Colorectal cancer:3.73e-4 (unfavourable), Breast cancer:6.18e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 80.8 CBY1 C22orf2, Cby, Chibby, PGEA1, PIGEA-14, PIGEA14 ENSG00000100211 Chibby homolog 1 (Drosophila) 22 38656636-38673854 Predicted intracellular proteins Evidence at protein level Endometrial cancer:5.22e-5 (favourable) Expressed in all Expressed in all fallopian tube: 95.4 CC2D1A FLJ20241, MRT3 ENSG00000132024 Coiled-coil and C2 domain containing 1A 19 13906201-13930879 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005436, CAB015220 Supported Supported Nucleoli fibrillar center
Plasma membrane
Cytosol Head and neck cancer:7.02e-4 (favourable) Expressed in all Expressed in all duodenum: 36.6 CC2D1B KIAA1836 ENSG00000154222 Coiled-coil and C2 domain containing 1B 1 52345723-52366193 Predicted intracellular proteins Evidence at protein level HPA027500, HPA031426 Uncertain Supported Nucleoplasm
Vesicles Liver cancer:1.45e-5 (unfavourable) Expressed in all Expressed in all lung: 18.8 CCAR1 CARP-1, CARP1, FLJ10590 ENSG00000060339 Cell division cycle and apoptosis regulator 1 10 68721012-68792377 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA007856, HPA048513 Supported Supported Nucleoplasm
Golgi apparatus Liver cancer:1.41e-5 (unfavourable), Ovarian cancer:4.05e-5 (favourable), Renal cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all lymph node: 35.2 CCAR2 DBC-1, DBC1, KIAA1967, NET35 ENSG00000158941 Cell cycle and apoptosis regulator 2 8 22604632-22621514 Predicted intracellular proteins Evidence at protein level HPA019907, HPA019943, CAB072827, CAB072828 Supported Validated Nucleoplasm
Nuclear bodies Renal cancer:5.60e-4 (favourable) Expressed in all Expressed in all testis: 136.6 CCBL2 KAT3, RBM1, RP11-82K18.3 ENSG00000137944 Cysteine conjugate-beta lyase 2 1 88935773-88992953 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026538, HPA027168 Supported Approved Nucleoli
Cytosol Renal cancer:5.02e-6 (favourable), Breast cancer:3.19e-5 (favourable), Head and neck cancer:1.86e-4 (favourable), Ovarian cancer:2.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 42.1 CCDC106 HSU79303 ENSG00000173581 Coiled-coil domain containing 106 19 55641062-55653161 Predicted intracellular proteins Evidence at protein level HPA041925, HPA043219 Uncertain Supported Nucleus
Cytosol Renal cancer:7.54e-11 (favourable), Pancreatic cancer:2.23e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 29.9 CCDC107 MGC31967 ENSG00000159884 Coiled-coil domain containing 107 9 35658290-35661511 Predicted membrane proteins Evidence at protein level HPA016857, HPA050442 Validated Nucleoplasm
Plasma membrane Expressed in all Expressed in all adipose tissue: 63.0 CCDC115 ccp1, FLJ30131, MGC12981 ENSG00000136710 Coiled-coil domain containing 115 2 130338241-130342349 Predicted intracellular proteins Evidence at protein level HPA034598 Approved Supported Vesicles
Plasma membrane Breast cancer:7.59e-4 (favourable) Expressed in all Expressed in all ovary: 55.3 CCDC117 FLJ33814 ENSG00000159873 Coiled-coil domain containing 117 22 28772674-28789301 Predicted intracellular proteins Evidence at protein level HPA000826 Uncertain Approved Nucleus
Microtubules
Cytosol Mixed Expressed in all testis: 67.5 CCDC12 MGC23918 ENSG00000160799 Coiled-coil domain containing 12 3 46921726-46982010 Predicted intracellular proteins Evidence at protein level HPA056814, HPA060530 Approved Supported Nucleoplasm Renal cancer:1.15e-4 (favourable) Expressed in all Expressed in all lymph node: 58.9 CCDC124 ENSG00000007080 Coiled-coil domain containing 124 19 17933016-17943991 Predicted intracellular proteins Evidence at protein level HPA041708, HPA046765 Supported Validated Plasma membrane
Cytosol Liver cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 72.6 CCDC126 FLJ23031 ENSG00000169193 Coiled-coil domain containing 126 7 23597379-23644708 Predicted intracellular proteins Evidence at protein level HPA026883 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 61.6 CCDC127 FLJ25701 ENSG00000164366 Coiled-coil domain containing 127 5 196871-218215 Predicted intracellular proteins Evidence at protein level HPA045052 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:4.04e-6 (unfavourable), Renal cancer:5.95e-5 (unfavourable), Breast cancer:7.01e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.8 CCDC130 MGC10471 ENSG00000104957 Coiled-coil domain containing 130 19 13731760-13763296 Predicted intracellular proteins Evidence at protein level HPA056977 Approved Approved Vesicles Head and neck cancer:7.83e-5 (favourable), Urothelial cancer:1.82e-4 (favourable), Renal cancer:1.97e-4 (unfavourable), Pancreatic cancer:2.34e-4 (favourable) Expressed in all Expressed in all spleen: 25.3 CCDC137 MGC16597 ENSG00000185298 Coiled-coil domain containing 137 17 81666364-81673904 Predicted intracellular proteins Evidence at protein level HPA052637, HPA053914 Uncertain Validated Nucleoli Renal cancer:1.16e-7 (unfavourable), Liver cancer:1.35e-7 (unfavourable), Lung cancer:8.32e-4 (unfavourable) Expressed in all Expressed in all skin: 19.7 CCDC14 DKFZp434L1050, FLJ12892 ENSG00000175455 Coiled-coil domain containing 14 3 123897305-123961408 Predicted intracellular proteins Evidence at protein level HPA035278, HPA035279 Uncertain Validated Centrosome Renal cancer:3.50e-8 (unfavourable), Urothelial cancer:2.72e-5 (favourable), Prostate cancer:4.76e-4 (unfavourable), Liver cancer:4.82e-4 (unfavourable), Head and neck cancer:5.27e-4 (favourable) Expressed in all Expressed in all testis: 46.4 CCDC149 DKFZp761B107 ENSG00000181982 Coiled-coil domain containing 149 4 24806117-24980204 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044158, HPA047913 Uncertain Supported Nucleoli Endometrial cancer:6.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.1 CCDC159 ENSG00000183401 Coiled-coil domain containing 159 19 11344684-11354944 Predicted intracellular proteins Evidence at protein level HPA047126, HPA054655 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Endometrial cancer:1.87e-7 (favourable), Pancreatic cancer:1.42e-4 (favourable), Urothelial cancer:8.62e-4 (favourable), Ovarian cancer:9.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 64.3 CCDC167 C6orf129, dJ153P14.2 ENSG00000198937 Coiled-coil domain containing 167 6 37482920-37499922 Predicted membrane proteins Evidence at protein level HPA045215 Uncertain Approved Cytosol Renal cancer:1.71e-7 (unfavourable), Liver cancer:2.94e-4 (unfavourable), Cervical cancer:7.59e-4 (favourable) Expressed in all Expressed in all tonsil: 57.5 CCDC174 C3orf19, FLJ33839 ENSG00000154781 Coiled-coil domain containing 174 3 14651746-14672659 Predicted intracellular proteins Evidence at protein level HPA043468, HPA060129 Approved Validated Nucleoplasm Urothelial cancer:3.81e-5 (favourable), Prostate cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all ovary: 17.9 CCDC186 C10orf118, FLJ10188, FLJ35301 ENSG00000165813 Coiled-coil domain containing 186 10 114120862-114174220 Predicted intracellular proteins Evidence at protein level HPA014569, HPA018019 Approved Approved Golgi apparatus Renal cancer:7.65e-8 (favourable) Expressed in all Expressed in all testis: 32.2 CCDC22 CXorf37, JM1 ENSG00000101997 Coiled-coil domain containing 22 X 49235467-49250526 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000888 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:2.17e-4 (unfavourable) Expressed in all Expressed in all spleen: 18.8 CCDC25 FLJ10853 ENSG00000147419 Coiled-coil domain containing 25 8 27733311-27772653 Predicted intracellular proteins Evidence at protein level HPA023256 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.11e-7 (favourable) Expressed in all Expressed in all duodenum: 36.6 CCDC28A C6orf80, CCRL1AP, DKFZp586D0623 ENSG00000024862 Coiled-coil domain containing 28A 6 138773509-138793319 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055125 Approved Approved Cytosol Renal cancer:1.11e-5 (favourable) Expressed in all Expressed in all thyroid gland: 90.3 CCDC43 FLJ31795 ENSG00000180329 Coiled-coil domain containing 43 17 44673069-44689779 Predicted intracellular proteins Evidence at protein level HPA023391 Approved Validated Cytosol Head and neck cancer:3.42e-5 (unfavourable), Liver cancer:1.33e-4 (unfavourable), Pancreatic cancer:3.19e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 26.1 CCDC47 GK001 ENSG00000108588 Coiled-coil domain containing 47 17 63745250-63776351 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029674, HPA072573 Approved Validated Endoplasmic reticulum Colorectal cancer:2.17e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 159.7 CCDC50 C3orf6, DFNA44, Ymer ENSG00000152492 Coiled-coil domain containing 50 3 191329077-191398670 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001336 Approved Supported Cytosol Liver cancer:2.48e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 49.4 CCDC53 CGI-116 ENSG00000120860 Coiled-coil domain containing 53 12 102012927-102062149 Predicted intracellular proteins Evidence at protein level HPA038338, HPA038339 Approved Approved Vesicles Expressed in all Expressed in all testis: 164.4 CCDC57 FLJ00130, FLJ23754 ENSG00000176155 Coiled-coil domain containing 57 17 82101460-82212830 Predicted intracellular proteins Evidence at protein level HPA023315, HPA023326, HPA023342, HPA023344 Approved Approved Microtubules
Microtubule organizing center
Cytosol Renal cancer:2.28e-6 (unfavourable), Pancreatic cancer:5.55e-5 (favourable) Expressed in all Expressed in all testis: 16.1 CCDC58 FLJ33273 ENSG00000160124 Coiled-coil domain containing 58 3 122359591-122383231 Predicted intracellular proteins Evidence at protein level HPA047777, HPA051965 Approved Approved Nucleoli
Mitochondria Liver cancer:2.94e-5 (unfavourable), Endometrial cancer:1.53e-4 (unfavourable), Urothelial cancer:7.29e-4 (favourable) Expressed in all Expressed in all kidney: 47.1 CCDC59 BR22, HSPC128, TAP26 ENSG00000133773 Coiled-coil domain containing 59 12 82223681-82358805 Predicted intracellular proteins Evidence at protein level HPA038555 Approved Approved Nucleus
Nucleoli Renal cancer:1.39e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 27.6 CCDC6 D10S170, H4, PTC, TPC, TST1 ENSG00000108091 Coiled-coil domain containing 6 10 59788763-59906656 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019049, HPA019051 Supported Supported Cytosol Liver cancer:1.11e-4 (unfavourable), Pancreatic cancer:3.95e-4 (unfavourable), Head and neck cancer:5.48e-4 (favourable) Expressed in all Expressed in all smooth muscle: 43.8 CCDC61 ENSG00000104983 Coiled-coil domain containing 61 19 45995461-46021318 Predicted intracellular proteins Evidence at protein level HPA040325, HPA061548 Uncertain Approved Nucleus Expressed in all Expressed in all testis: 31.1 CCDC69 DKFZP434C171, FLJ13705 ENSG00000198624 Coiled-coil domain containing 69 5 151181052-151224145 Predicted intracellular proteins Evidence at protein level HPA043648, HPA052896 Uncertain Approved Golgi apparatus
Plasma membrane
Actin filaments Breast cancer:3.21e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 113.1 CCDC71 FLJ12800 ENSG00000177352 Coiled-coil domain containing 71 3 49162535-49166321 Predicted intracellular proteins Evidence at protein level HPA047547 Uncertain Approved Nuclear membrane Renal cancer:9.65e-9 (favourable) Expressed in all Expressed in all thyroid gland: 27.2 CCDC82 FLJ23518 ENSG00000149231 Coiled-coil domain containing 82 11 96352769-96389923 Predicted intracellular proteins Evidence at protein level HPA038704 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all testis: 55.3 CCDC85C ENSG00000205476 Coiled-coil domain containing 85C 14 99500180-99604026 Predicted intracellular proteins Evidence at protein level HPA058346 Uncertain Approved Nuclear speckles
Cell Junctions Renal cancer:2.60e-5 (favourable), Endometrial cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all esophagus: 31.3 CCDC88A APE, FLJ10392, GIV, GRDN, HkRP1, KIAA1212 ENSG00000115355 Coiled-coil domain containing 88A 2 55287842-55419921 Predicted intracellular proteins Evidence at protein level HPA038101, HPA038102 Supported Renal cancer:5.98e-8 (unfavourable), Endometrial cancer:2.06e-4 (unfavourable), Liver cancer:4.86e-4 (unfavourable) Expressed in all Expressed in all testis: 116.9 CCDC9 DKFZP586M1019 ENSG00000105321 Coiled-coil domain containing 9 19 47255980-47271953 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045624, HPA072007 Approved Approved Cytosol Expressed in all Expressed in all testis: 30.3 CCDC90B MDS011, MDS025 ENSG00000137500 Coiled-coil domain containing 90B 11 83259097-83286407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011130, HPA011931 Supported Validated Mitochondria Expressed in all Expressed in all testis: 96.2 CCDC91 DKFZp779L1558, FLJ11088, p56 ENSG00000123106 Coiled-coil domain containing 91 12 28133249-28581511 Predicted intracellular proteins Evidence at protein level HPA038169 Approved Supported Nucleoplasm
Golgi apparatus Liver cancer:1.05e-4 (unfavourable), Renal cancer:7.69e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 43.0 CCDC93 FLJ10996 ENSG00000125633 Coiled-coil domain containing 93 2 117915478-118014133 Predicted intracellular proteins Evidence at protein level HPA054183 Approved Supported Vesicles
Plasma membrane Liver cancer:2.97e-6 (unfavourable), Thyroid cancer:9.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.5 CCDC94 FLJ10374 ENSG00000105248 Coiled-coil domain containing 94 19 4247079-4269090 Predicted intracellular proteins Evidence at protein level HPA043606, HPA055675 Approved Supported Nucleoplasm Renal cancer:6.32e-4 (favourable), Stomach cancer:8.04e-4 (favourable) Expressed in all Expressed in all bone marrow: 28.0 CCDC97 FLJ40267, MGC20255 ENSG00000142039 Coiled-coil domain containing 97 19 41310189-41324883 Predicted intracellular proteins Evidence at protein level HPA043320, HPA043572 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all testis: 58.7 CCL2 GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF ENSG00000108691 Chemokine (C-C motif) ligand 2 17 34255218-34257203 Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB013676, HPA019163 Approved Approved Golgi apparatus
Vesicles Renal cancer:4.51e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 412.4 CCM2 C7orf22, MGC4607, OSM ENSG00000136280 Cerebral cavernous malformation 2 7 44999475-45076469 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020273, HPA021669, HPA065815 Supported Validated Mitochondria Renal cancer:5.06e-7 (unfavourable), Pancreatic cancer:1.16e-4 (favourable), Colorectal cancer:1.79e-4 (unfavourable), Glioma:3.77e-4 (unfavourable) Expressed in all Expressed in all lymph node: 49.8 CCNB1IP1 C14orf18, HEI10 ENSG00000100814 Cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 14 20311368-20333312 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:5.18e-6 (favourable) Expressed in all Expressed in all ovary: 120.3 CCNC CycC ENSG00000112237 Cyclin C 6 99542380-99568973 Predicted intracellular proteins Evidence at protein level CAB010499, HPA069322 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:8.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 99.7 CCND3 ENSG00000112576 Cyclin D3 6 41934933-42050357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB000116, HPA055107 Approved Supported Plasma membrane
Focal adhesion sites
Cytosol Thyroid cancer:8.08e-6 (favourable) Expressed in all Expressed in all lymph node: 161.4 CCNG1 CCNG ENSG00000113328 Cyclin G1 5 163437569-163446151 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000350 Supported Supported Nucleoplasm Colorectal cancer:7.00e-4 (favourable) Expressed in all Expressed in all duodenum: 141.4 CCNG2 ENSG00000138764 Cyclin G2 4 77157151-77433388 Cancer-related genes, Predicted intracellular proteins Evidence at transcript level HPA034684 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.47e-5 (favourable), Pancreatic cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all esophagus: 151.2 CCNH CycH, p34, p37 ENSG00000134480 Cyclin H 5 87391494-87413019 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB019416, HPA044138 Approved Supported Nucleoplasm Renal cancer:3.92e-5 (unfavourable), Ovarian cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all testis: 88.5 CCNI CCNI1 ENSG00000118816 Cyclin I 4 77047158-77076005 Predicted intracellular proteins Evidence at protein level CAB010206, HPA039853, HPA061470 Uncertain Supported Nucleoplasm
Nuclear bodies
Golgi apparatus Renal cancer:2.10e-4 (favourable) Expressed in all Expressed in all thyroid gland: 451.7 CCNJ bA690P14.1, FLJ10895 ENSG00000107443 Cyclin J 10 96043394-96060870 Predicted intracellular proteins Evidence at transcript level HPA036531, HPA058151 Approved Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 9.8 CCNK CPR4 ENSG00000090061 Cyclin K 14 99481169-99535044 Predicted intracellular proteins Evidence at protein level HPA000645 Supported Nucleoplasm Expressed in all Expressed in all testis: 83.9 CCNL1 ania-6a ENSG00000163660 Cyclin L1 3 157146508-157160760 Predicted secreted proteins Evidence at protein level HPA057911 Supported Nucleoplasm
Nuclear bodies Urothelial cancer:6.96e-7 (favourable), Renal cancer:1.01e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 28.8 CCNL2 ania-6b, CCNM, CCNS, HLA-ISO, PCEE, SB138 ENSG00000221978 Cyclin L2 1 1385711-1399328 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053137 Supported Supported Nucleoplasm Urothelial cancer:1.46e-7 (favourable), Renal cancer:1.12e-6 (unfavourable) Expressed in all Expressed in all endometrium: 68.4 CCNT1 CCNT, CYCT1, HIVE1 ENSG00000129315 Cyclin T1 12 48688458-48716998 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004892, CAB009016 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 19.8 CCNT2 ENSG00000082258 Cyclin T2 2 134918235-134959342 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005559 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.25e-5 (unfavourable), Prostate cancer:2.44e-4 (unfavourable), Urothelial cancer:3.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.7 CCNY C10orf9, CBCP1, CFP1 ENSG00000108100 Cyclin Y 10 35247025-35572669 Predicted intracellular proteins Evidence at protein level HPA036290 Approved Liver cancer:6.75e-5 (unfavourable) Expressed in all Expressed in all testis: 149.6 CCNYL1 FLJ40432 ENSG00000163249 Cyclin Y-like 1 2 207711540-207761839 Predicted intracellular proteins Evidence at protein level HPA046825 Approved Approved Plasma membrane Expressed in all Expressed in all testis: 30.3 CCPG1 CPR8, KIAA1254 ENSG00000260916 Cell cycle progression 1 15 55340032-55408510 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009432, HPA026861 Approved Approved Endoplasmic reticulum
Golgi apparatus Stomach cancer:5.02e-5 (unfavourable), Renal cancer:5.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 139.9 CCS ENSG00000173992 Copper chaperone for superoxide dismutase 11 66592821-66606019 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008672, HPA040026, HPA044090 Approved Expressed in all Expressed in all parathyroid gland: 21.8 CCSER2 FAM190B, KIAA1128 ENSG00000107771 Coiled-coil serine-rich protein 2 10 84328586-84518521 Predicted intracellular proteins Evidence at protein level HPA037481, HPA037482 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 39.6 CCT2 Cctb ENSG00000166226 Chaperonin containing TCP1, subunit 2 (beta) 12 69585334-69601570 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003197, HPA003198 Supported Supported Cytosol Liver cancer:3.61e-9 (unfavourable), Prostate cancer:3.67e-4 (unfavourable), Head and neck cancer:8.38e-4 (unfavourable) Expressed in all Expressed in all testis: 365.6 CCT3 Cctg, TRIC5 ENSG00000163468 Chaperonin containing TCP1, subunit 3 (gamma) 1 156308968-156367873 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006543 Approved Supported Plasma membrane
Cytosol Liver cancer:3.87e-7 (unfavourable), Renal cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all testis: 205.6 CCT4 Cctd ENSG00000115484 Chaperonin containing TCP1, subunit 4 (delta) 2 61868089-61888804 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029349 Supported Supported Nucleoplasm
Cytosol Liver cancer:9.37e-12 (unfavourable), Breast cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all testis: 133.5 CCT5 KIAA0098 ENSG00000150753 Chaperonin containing TCP1, subunit 5 (epsilon) 5 10249921-10266412 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002238, HPA005958, CAB006271 Supported Supported Nucleoli
Cytosol Liver cancer:6.57e-11 (unfavourable), Renal cancer:8.23e-6 (unfavourable) Expressed in all Expressed in all testis: 190.1 CCT6A CCT6, Cctz, HTR3, TCP20, TCPZ, TTCP20 ENSG00000146731 Chaperonin containing TCP1, subunit 6A (zeta 1) 7 56051630-56063989 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042996, HPA045576, HPA049949 Supported Approved Cytosol Liver cancer:9.00e-10 (unfavourable), Renal cancer:2.19e-4 (unfavourable), Breast cancer:4.04e-4 (unfavourable), Head and neck cancer:8.45e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 118.2 CCT7 Ccth, Nip7-1 ENSG00000135624 Chaperonin containing TCP1, subunit 7 (eta) 2 73233420-73253021 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008425 Approved Approved Cytosol Liver cancer:1.84e-5 (unfavourable), Endometrial cancer:2.69e-4 (unfavourable) Expressed in all Expressed in all testis: 285.7 CCT8 C21orf112, Cctq, PRED71 ENSG00000156261 Chaperonin containing TCP1, subunit 8 (theta) 21 29055805-29073797 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018520, HPA021051, HPA029426 Supported Approved Nucleus
Intermediate filaments
Cytosol Liver cancer:1.56e-5 (unfavourable) Expressed in all Expressed in all lymph node: 137.5 CCZ1 C7orf28A, CCZ1A, CGI-43 ENSG00000122674 CCZ1 homolog, vacuolar protein trafficking and biogenesis associated 7 5898725-5926550 Predicted intracellular proteins Evidence at protein level HPA045114, HPA050006 Uncertain Validated Vesicles Expressed in all Expressed in all parathyroid gland: 73.7 CCZ1B C7orf28B, DKFZP586I1023, H_NH0577018.2, MGC19819 ENSG00000146574 CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated 7 6794134-6826770 Predicted intracellular proteins Evidence at protein level HPA045114, HPA050006 Uncertain Validated Vesicles Mixed Expressed in all parathyroid gland: 48.7 CD14 ENSG00000170458 CD14 molecule 5 140631728-140633701 Cancer-related genes, CD markers, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001887, HPA002127, CAB033631, CAB072865, CAB072866 Supported Supported Vesicles Renal cancer:6.80e-5 (unfavourable) Expressed in all Expressed in all appendix: 273.9 CD151 PETA-3, RAPH, SFA-1, TSPAN24 ENSG00000177697 CD151 molecule (Raph blood group) 11 832843-839831 Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002428, HPA011906 Supported Liver cancer:5.58e-4 (unfavourable), Thyroid cancer:6.92e-4 (favourable), Lung cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 356.5 CD164 DFNA66, MGC-24, MUC-24 ENSG00000135535 CD164 molecule, sialomucin 6 109366514-109382559 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010636 Uncertain Expressed in all Expressed in all thyroid gland: 608.3 CD2AP CMS ENSG00000198087 CD2-associated protein 6 47477789-47627263 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003267, HPA003326, CAB004352 Supported Validated Plasma membrane
Cytosol Pancreatic cancer:5.53e-5 (unfavourable), Urothelial cancer:7.57e-5 (favourable) Expressed in all Expressed in all small intestine: 66.9 CD2BP2 LIN1, PPP1R59, Snu40 ENSG00000169217 CD2 (cytoplasmic tail) binding protein 2 16 30350766-30355361 Predicted intracellular proteins Evidence at protein level HPA041508, HPA061309 Supported Validated Nuclear speckles
Cytosol Liver cancer:1.84e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 79.8 CD302 BIMLEC, CLEC13A, DCL-1, KIAA0022 ENSG00000241399 CD302 molecule 2 159768630-159798255 CD markers, Predicted membrane proteins Evidence at protein level Mixed Expressed in all liver: 98.7 CD320 8D6, 8D6A ENSG00000167775 CD320 molecule 19 8302127-8308356 CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level HPA014500, HPA073489 Uncertain Approved Cytosol Liver cancer:4.02e-4 (unfavourable) Expressed in all Expressed in all epididymis: 75.7 CD34 ENSG00000174059 CD34 molecule 1 207880972-207911402 CD markers, Predicted membrane proteins Evidence at protein level CAB000018, HPA036722, HPA036723 Supported Approved Nucleus
Plasma membrane
Cell Junctions Head and neck cancer:5.93e-5 (favourable), Renal cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all placenta: 313.8 CD36 FAT, GP3B, GP4, GPIV, SCARB3 ENSG00000135218 CD36 molecule (thrombospondin receptor) 7 80369575-80679277 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA002018, CAB025866 Supported Stomach cancer:4.47e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 1614.0 CD40 Bp50, p50, TNFRSF5 ENSG00000101017 CD40 molecule, TNF receptor superfamily member 5 20 46118272-46129863 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002495, HPA031567, HPA031568, CAB072868 Supported Renal cancer:4.48e-4 (unfavourable) Expressed in all Expressed in all lymph node: 65.6 CD44 CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1 ENSG00000026508 CD44 molecule (Indian blood group) 11 35138870-35232402 Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000112, CAB000316, HPA005785 Supported Validated Golgi apparatus
Plasma membrane Renal cancer:1.78e-8 (unfavourable) Expressed in all Expressed in all skin: 505.8 CD46 MCP, MGC26544, MIC10, TLX, TRA2.10 ENSG00000117335 CD46 molecule, complement regulatory protein 1 207752057-207795513 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB010401, HPA016903 Supported Approved Plasma membrane Cervical cancer:8.54e-5 (unfavourable), Stomach cancer:2.38e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 483.7 CD47 IAP, MER6, OA3 ENSG00000196776 CD47 molecule 3 108043298-108091025 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB016055, HPA044659 Approved Supported Golgi apparatus
Vesicles
Plasma membrane Thyroid cancer:7.29e-5 (favourable), Renal cancer:1.69e-4 (unfavourable), Endometrial cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all lung: 204.9 CD53 MOX44, TSPAN25 ENSG00000143119 CD53 molecule 1 110873154-110899928 CD markers, Predicted membrane proteins Evidence at protein level HPA047216 Approved Renal cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all lymph node: 468.7 CD55 CR, CROM, DAF, TC ENSG00000196352 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1 207321508-207386804 Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002190, CAB010454, HPA024386 Supported Uncertain Vesicles
Midbody ring Renal cancer:9.36e-4 (unfavourable) Expressed in all Expressed in all lung: 324.6 CD58 LFA3 ENSG00000116815 CD58 molecule 1 116514535-116571039 CD markers, Predicted membrane proteins Evidence at protein level Liver cancer:2.32e-6 (unfavourable), Pancreatic cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all lung: 42.7 CD59 16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20 ENSG00000085063 CD59 molecule, complement regulatory protein 11 33698261-33736445 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB001448, HPA026494 Supported Approved Golgi apparatus
Vesicles Renal cancer:1.39e-10 (favourable), Pancreatic cancer:2.92e-5 (unfavourable), Head and neck cancer:3.10e-5 (unfavourable), Cervical cancer:3.81e-5 (unfavourable), Stomach cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all epididymis: 907.3 CD63 ME491, MLA1, TSPAN30 ENSG00000135404 CD63 molecule 12 55725323-55729707 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA010088, CAB026356 Supported Supported Vesicles Liver cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all epididymis: 1712.6 CD68 DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1 ENSG00000129226 CD68 molecule 17 7579467-7582113 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000051, CAB000066, HPA048982, CAB072861, CAB072862 Supported Supported Golgi apparatus
Vesicles Renal cancer:1.14e-5 (unfavourable) Mixed Expressed in all lung: 534.2 CD74 DHLAG ENSG00000019582 CD74 molecule, major histocompatibility complex, class II invariant chain 5 150401637-150412929 Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level CAB002506, HPA010592 Supported Supported Golgi apparatus Endometrial cancer:6.53e-6 (favourable), Breast cancer:1.06e-4 (favourable) Expressed in all Expressed in all spleen: 6665.5 CD81 TAPA-1, TAPA1, TSPAN28 ENSG00000110651 CD81 molecule 11 2376177-2397419 CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB002507, HPA007234 Supported Supported Plasma membrane Glioma:5.12e-5 (unfavourable), Pancreatic cancer:3.86e-4 (favourable), Colorectal cancer:7.56e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 2246.2 CD82 IA4, KAI1, R2, ST6, TSPAN27 ENSG00000085117 CD82 molecule 11 44564427-44620363 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002508, HPA028900, HPA061418 Supported Approved Vesicles Expressed in all Expressed in all esophagus: 132.1 CD9 BA2, MIC3, MRP-1, P24, TSPAN29 ENSG00000010278 CD9 molecule 12 6199715-6238271 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB002490 Supported Supported Plasma membrane Renal cancer:6.49e-5 (favourable), Thyroid cancer:8.93e-5 (favourable), Pancreatic cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all esophagus: 1009.8 CD93 C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4 ENSG00000125810 CD93 molecule 20 23079349-23086340 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA009300, HPA012368 Supported Approved Vesicles
Plasma membrane Renal cancer:2.74e-4 (unfavourable) Expressed in all Expressed in all placenta: 195.4 CD99 MIC2 ENSG00000002586 CD99 molecule X 2691179-2741309 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000020, HPA035304 Supported Approved Golgi apparatus Renal cancer:5.87e-7 (unfavourable) Expressed in all Expressed in all gallbladder: 376.9 CD99L2 CD99B, MIC2L1 ENSG00000102181 CD99 molecule-like 2 X 150766337-150898816 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038782, HPA038783 Supported Uncertain Golgi apparatus
Plasma membrane
Intermediate filaments Pancreatic cancer:2.74e-5 (favourable), Lung cancer:4.96e-4 (favourable), Urothelial cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 143.9 CDAN1 CDA-I, CDAI ENSG00000140326 Codanin 1 15 42723559-42737126 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039404, HPA040787 Supported Validated Plasma membrane
Cytosol Liver cancer:1.07e-4 (unfavourable) Expressed in all Expressed in all ovary: 15.1 CDC123 C10orf7, D123 ENSG00000151465 Cell division cycle 123 10 12195965-12250589 Predicted intracellular proteins Evidence at protein level HPA037830 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:3.16e-7 (unfavourable), Renal cancer:2.42e-6 (unfavourable) Expressed in all Expressed in all lymph node: 66.2 CDC16 ANAPC6, APC6, CUT9 ENSG00000130177 Cell division cycle 16 13 114234887-114272723 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA042826 Approved Expressed in all Expressed in all testis: 83.4 CDC23 ANAPC8, APC8, CUT23 ENSG00000094880 Cell division cycle 23 5 138187648-138213343 Predicted secreted proteins Evidence at protein level HPA039593 Approved Liver cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all placenta: 37.1 CDC26 ANAPC12, APC12, C9orf17 ENSG00000176386 Cell division cycle 26 9 113255835-113275589 Predicted intracellular proteins Evidence at protein level HPA044130 Approved Validated Nucleoplasm Liver cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.7 CDC27 ANAPC3, APC3, D0S1430E, D17S978E, NUC2 ENSG00000004897 Cell division cycle 27 17 47117703-47189422 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016315, HPA028129, HPA052399 Supported Validated Nucleoplasm Renal cancer:6.39e-5 (unfavourable), Colorectal cancer:1.77e-4 (favourable), Liver cancer:4.38e-4 (unfavourable), Lung cancer:8.15e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 71.1 CDC34 E2-CDC34, UBC3, UBE2R1 ENSG00000099804 Cell division cycle 34 19 531712-542092 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA002382, CAB005109, CAB047311 Approved Supported Nuclear speckles
Cytosol Liver cancer:7.57e-4 (unfavourable) Expressed in all Expressed in all testis: 63.5 CDC37 P50CDC37 ENSG00000105401 Cell division cycle 37 19 10391134-10420121 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA003928, CAB004214 Supported Validated Cytosol Stomach cancer:2.33e-4 (favourable) Expressed in all Expressed in all appendix: 114.0 CDC37L1 CDC37B, FLJ20639, HARC ENSG00000106993 Cell division cycle 37-like 1 9 4679559-4708398 Predicted intracellular proteins Evidence at protein level HPA021175 Approved Supported Cytosol Renal cancer:2.66e-7 (favourable) Expressed in all Expressed in all liver: 28.5 CDC40 EHB3, FLJ10564, PRP17, PRPF17 ENSG00000168438 Cell division cycle 40 6 110180141-110254275 Predicted secreted proteins Evidence at protein level HPA046620 Supported Nucleus Expressed in all Expressed in all thyroid gland: 27.0 CDC42 CDC42Hs, G25K ENSG00000070831 Cell division cycle 42 1 22052627-22092946 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004360 Approved Validated Microtubules
Cytokinetic bridge Liver cancer:5.28e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 253.0 CDC42BPA FLJ23347, KIAA0451, MRCK, MRCKA, PK428 ENSG00000143776 CDC42 binding protein kinase alpha (DMPK-like) 1 226989865-227318474 Enzymes, Predicted intracellular proteins Evidence at protein level HPA071252 Approved Intermediate filaments Expressed in all Expressed in all testis: 45.0 CDC42BPB KIAA1124, MRCKB ENSG00000198752 CDC42 binding protein kinase beta (DMPK-like) 14 102932379-103057462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022821 Approved Approved Nuclear speckles
Cytosol Renal cancer:8.67e-10 (favourable), Lung cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 75.3 CDC42EP1 Borg5, CEP1, MSE55 ENSG00000128283 CDC42 effector protein (Rho GTPase binding) 1 22 37560447-37569405 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006379 Approved Supported Plasma membrane
Actin filaments Expressed in all Expressed in all stomach: 107.7 CDC42EP3 BORG2, CEP3, UB1 ENSG00000163171 CDC42 effector protein (Rho GTPase binding) 3 2 37641882-37738468 Predicted intracellular proteins Evidence at protein level HPA034986 Approved Approved Nucleoli
Cytosol Expressed in all Expressed in all endometrium: 150.3 CDC42EP4 BORG4, CEP4, KAIA1777, MGC17125, MGC3740 ENSG00000179604 CDC42 effector protein (Rho GTPase binding) 4 17 73283624-73312175 Predicted intracellular proteins Evidence at protein level HPA023335, HPA024797 Approved Supported Validated Plasma membrane
Actin filaments
Microtubules Expressed in all Expressed in all cerebral cortex: 102.1 CDC42SE1 SCIP1, SPEC1 ENSG00000197622 CDC42 small effector 1 1 151050971-151070325 Predicted intracellular proteins Evidence at protein level HPA027634 Approved Supported Plasma membrane Renal cancer:2.19e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 117.1 CDC42SE2 FLJ21967, SPEC2 ENSG00000158985 CDC42 small effector 2 5 131245493-131398447 Predicted intracellular proteins Evidence at protein level HPA038624 Supported Colorectal cancer:4.50e-5 (favourable), Urothelial cancer:7.50e-4 (favourable) Expressed in all Expressed in all lymph node: 94.1 CDC5L CDC5, CEF1, hCDC5, PCDC5RP ENSG00000096401 Cell division cycle 5-like 6 44387525-44450426 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006302, HPA011361, CAB012275 Supported Supported Nucleoplasm Melanoma:7.02e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.6 CDC73 C1orf28, FIHP, HRPT1, HRPT2, parafibromin ENSG00000134371 Cell division cycle 73 1 193122017-193253901 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016359, HPA030772 Supported Supported Nucleus
Cytosol Expressed in all Expressed in all thyroid gland: 32.0 CDCA7L JPO2, R1, RAM2 ENSG00000164649 Cell division cycle associated 7-like 7 21900900-21946084 Predicted intracellular proteins Evidence at protein level HPA027169 Approved Supported Nucleus
Nucleoli
Cytosol Liver cancer:4.36e-6 (unfavourable), Renal cancer:1.98e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 45.8 CDIP1 C16orf5, CDIP, LITAFL ENSG00000089486 Cell death-inducing p53 target 1 16 4510675-4538828 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049352 Approved Supported Nucleoplasm
Centrosome Renal cancer:1.14e-6 (favourable), Pancreatic cancer:2.14e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 73.2 CDIPT PIS, PIS1 ENSG00000103502 CDP-diacylglycerol--inositol 3-phosphatidyltransferase 16 29858357-29863736 Enzymes, Predicted membrane proteins Evidence at protein level HPA056597 Approved Approved Nucleoplasm
Nuclear membrane
Plasma membrane Cervical cancer:9.40e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 110.5 CDK10 PISSLRE ENSG00000185324 Cyclin-dependent kinase 10 16 89680737-89696364 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059634, HPA067060 Supported Nucleoplasm
Midbody
Midbody ring Pancreatic cancer:2.69e-4 (favourable), Urothelial cancer:3.63e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.4 CDK11A CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE ENSG00000008128 Cyclin-dependent kinase 11A 1 1702730-1724324 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010467, HPA025061, HPA073626 Supported Supported Nuclear speckles
Cytosol Renal cancer:1.15e-6 (unfavourable), Melanoma:5.06e-4 (unfavourable) Expressed in all Expressed in all small intestine: 35.8 CDK11B CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58 ENSG00000248333 Cyclin-dependent kinase 11B 1 1635227-1659012 Predicted intracellular proteins Evidence at protein level HPA025061, HPA073626 Approved Approved Nuclear speckles Head and neck cancer:1.14e-4 (favourable) Expressed in all Expressed in all testis: 46.8 CDK12 CRK7, CRKR, CRKRS, KIAA0904 ENSG00000167258 Cyclin-dependent kinase 12 17 39461511-39564907 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008038 Supported Supported Nucleus Expressed in all Expressed in all testis: 33.8 CDK13 CDC2L, CDC2L5, CHED, KIAA1791 ENSG00000065883 Cyclin-dependent kinase 13 7 39950037-40097134 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059241 Uncertain Supported Nuclear speckles Expressed in all Expressed in all parathyroid gland: 32.9 CDK14 PFTAIRE1, PFTK1 ENSG00000058091 Cyclin-dependent kinase 14 7 90466424-91210590 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015267 Approved Supported Nucleus
Cytosol Breast cancer:5.86e-4 (favourable), Stomach cancer:7.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 56.8 CDK16 FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1 ENSG00000102225 Cyclin-dependent kinase 16 X 47217860-47229997 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000974, HPA001366, CAB016535 Approved Uncertain Plasma membrane
Microtubules
Cytosol Liver cancer:2.02e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 97.2 CDK17 PCTAIRE2, PCTK2 ENSG00000059758 Cyclin-dependent kinase 17 12 96278261-96400560 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015325 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.09e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 72.0 CDK2 ENSG00000123374 Cyclin-dependent kinase 2 12 55966769-55972784 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013115, HPA066915 Supported Validated Nucleoplasm
Centrosome
Cytosol Renal cancer:1.46e-10 (unfavourable), Liver cancer:8.61e-5 (unfavourable), Head and neck cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 65.0 CDK2AP1 doc-1, DOC1, DORC1, p12DOC-1, ST19 ENSG00000111328 Cyclin-dependent kinase 2 associated protein 1 12 123260971-123272334 Predicted intracellular proteins Evidence at protein level CAB019377, HPA057648, HPA068833 Approved Validated Nucleoplasm Renal cancer:5.27e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 294.8 CDK2AP2 DOC-1R, p14 ENSG00000167797 Cyclin-dependent kinase 2 associated protein 2 11 67506497-67508649 Predicted intracellular proteins Evidence at protein level HPA047599 Uncertain Approved Nucleoplasm Renal cancer:5.20e-4 (unfavourable), Endometrial cancer:8.80e-4 (favourable) Expressed in all Expressed in all epididymis: 49.8 CDK4 PSK-J3 ENSG00000135446 Cyclin-dependent kinase 4 12 57747727-57756013 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006024, CAB069405 Approved Supported Nucleus
Nuclear membrane
Nucleoli
Cytosol Liver cancer:2.09e-7 (unfavourable), Renal cancer:3.15e-5 (unfavourable) Expressed in all Expressed in all endometrium: 120.2 CDK5 PSSALRE ENSG00000164885 Cyclin-dependent kinase 5 7 151053812-151058530 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB008909, HPA018977, HPA064535 Approved Supported Nucleus
Plasma membrane
Cell Junctions
Cytosol Expressed in all Expressed in all cerebral cortex: 50.0 CDK5RAP1 C20orf34, C42, CGI-05, HSPC167 ENSG00000101391 CDK5 regulatory subunit associated protein 1 20 33358839-33401561 Predicted intracellular proteins Evidence at protein level HPA066301 Approved Nuclear speckles
Mitochondria Prostate cancer:8.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.4 CDK5RAP2 C48, CEP215, FLJ10867, MCPH3 ENSG00000136861 CDK5 regulatory subunit associated protein 2 9 120388869-120580170 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035820, HPA046529 Approved Validated Cell Junctions
Centrosome Expressed in all Expressed in all testis: 37.2 CDK5RAP3 C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114 ENSG00000108465 CDK5 regulatory subunit associated protein 3 17 47967810-47981774 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022141, HPA022882, HPA027883 Supported Supported Cytosol Renal cancer:3.61e-5 (unfavourable), Urothelial cancer:7.31e-5 (favourable) Expressed in all Expressed in all epididymis: 107.9 CDK8 K35 ENSG00000132964 Cyclin-dependent kinase 8 13 26254104-26405238 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044721 Approved Nucleus Stomach cancer:9.23e-4 (favourable) Expressed in all Expressed in all testis: 17.6 CDK9 C-2k, CDC2L4, PITALRE, TAK ENSG00000136807 Cyclin-dependent kinase 9 9 127785679-127790787 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004216, HPA006738 Supported Approved Nucleoplasm
Cytoplasmic bodies Renal cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all ovary: 60.3 CDKAL1 FLJ20342 ENSG00000145996 CDK5 regulatory subunit associated protein 1-like 1 6 20534457-21232404 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057474 Uncertain Vesicles Endometrial cancer:1.03e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 15.9 CDKN1A CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1 ENSG00000124762 Cyclin-dependent kinase inhibitor 1A (p21, Cip1) 6 36676460-36687339 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB000064, HPA005946, CAB069401 Supported Supported Nucleoplasm
Nuclear bodies Endometrial cancer:3.14e-5 (favourable), Renal cancer:4.95e-5 (favourable), Lung cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 205.5 CDKN1B KIP1, P27KIP1 ENSG00000111276 Cyclin-dependent kinase inhibitor 1B (p27, Kip1) 12 12715058-12722371 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB003691, CAB021888, HPA059086 Approved Supported Nucleus
Vesicles Liver cancer:3.25e-4 (unfavourable), Colorectal cancer:5.15e-4 (favourable), Renal cancer:8.39e-4 (unfavourable) Expressed in all Expressed in all ovary: 72.9 CDKN2AIP CARF, FLJ20036 ENSG00000168564 CDKN2A interacting protein 4 183444591-183448198 Predicted intracellular proteins Evidence at protein level HPA041397, HPA062142 Approved Validated Nucleoplasm Renal cancer:3.00e-5 (favourable) Expressed in all Expressed in all testis: 37.5 CDKN2AIPNL MGC13017 ENSG00000237190 CDKN2A interacting protein N-terminal like 5 134402087-134411898 Predicted intracellular proteins Evidence at protein level HPA043966 Approved Expressed in all Expressed in all thyroid gland: 35.3 CDKN2C INK4C, p18 ENSG00000123080 Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1 50960745-50974633 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005303, CAB018398, HPA019057, HPA019764 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.70e-10 (unfavourable), Liver cancer:1.58e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 80.3 CDR2 CDR62, Yo ENSG00000140743 Cerebellar degeneration-related protein 2, 62kDa 16 22345936-22437165 Predicted intracellular proteins Evidence at protein level HPA018151, HPA023870 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 112.0 CDS2 ENSG00000101290 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 20 5126786-5197887 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA019698 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:3.53e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 49.1 CDV3 H41 ENSG00000091527 CDV3 homolog (mouse) 3 133573730-133590261 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029761, HPA029762, HPA029763 Supported Validated Nucleoli
Plasma membrane
Cytosol Liver cancer:5.21e-6 (unfavourable) Expressed in all Expressed in all lymph node: 187.9 CDYL CDYL1, DKFZP586C1622 ENSG00000153046 Chromodomain protein, Y-like 6 4706159-4955551 Enzymes, Predicted intracellular proteins Evidence at protein level CAB012249, HPA035577, HPA035578 Supported Validated Nucleoplasm
Nuclear speckles Glioma:2.10e-4 (favourable), Liver cancer:2.20e-4 (unfavourable), Melanoma:7.52e-4 (unfavourable) Expressed in all Expressed in all placenta: 27.5 CEBPA C/EBP-alpha, CEBP ENSG00000245848 CCAAT/enhancer binding protein (C/EBP), alpha 19 33299934-33302564 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052734, HPA065037, HPA067937 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all adipose tissue: 107.9 CEBPB C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5 ENSG00000172216 CCAAT/enhancer binding protein (C/EBP), beta 20 50190734-50192689 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004213, HPA061355, HPA062267 Supported Validated Nucleoplasm Renal cancer:2.44e-12 (unfavourable) Expressed in all Expressed in all adrenal gland: 112.9 CEBPD C/EBP-delta, CELF, CRP3, NF-IL6-beta ENSG00000221869 CCAAT/enhancer binding protein (C/EBP), delta 8 47736909-47739086 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067581 Supported Nucleoplasm Renal cancer:2.87e-7 (unfavourable), Breast cancer:2.28e-5 (favourable) Expressed in all Expressed in all adipose tissue: 71.2 CEBPG GPE1BP, IG/EBP-1 ENSG00000153879 CCAAT/enhancer binding protein (C/EBP), gamma 19 33373330-33382686 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA012024 Supported Supported Nucleoplasm Endometrial cancer:7.97e-5 (unfavourable), Renal cancer:7.23e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 41.2 CEBPZ CBF2, CTF2 ENSG00000115816 CCAAT/enhancer binding protein (C/EBP), zeta 2 37201612-37231713 Predicted intracellular proteins Evidence at protein level HPA052065 Uncertain Approved Nucleus
Vesicles Liver cancer:2.94e-5 (unfavourable), Endometrial cancer:5.07e-4 (unfavourable), Pancreatic cancer:8.13e-4 (unfavourable) Expressed in all Expressed in all testis: 68.2 CEBPZOS CEBPZ-AS1 ENSG00000218739 CEBPZ opposite strand 2 37196488-37216193 Predicted membrane proteins Evidence at protein level HPA053866 Uncertain Approved Nucleoplasm Renal cancer:3.46e-7 (unfavourable), Liver cancer:1.72e-6 (unfavourable) Expressed in all Expressed in all epididymis: 48.4 CECR1 ADGF, IDGFL ENSG00000093072 Cat eye syndrome chromosome region, candidate 1 22 17178790-17221989 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007888 Approved Pancreatic cancer:8.91e-4 (favourable), Ovarian cancer:9.26e-4 (favourable) Expressed in all Expressed in all spleen: 164.1 CECR5 ENSG00000069998 Cat eye syndrome chromosome region, candidate 5 22 17137511-17165287 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005548 Approved Approved Mitochondria Expressed in all Expressed in all duodenum: 27.4 CELF1 BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, hNab50, NAB50, NAPOR ENSG00000149187 CUGBP, Elav-like family member 1 11 47465944-47565569 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016114, HPA044597 Supported Validated Nucleoplasm Liver cancer:7.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 130.7 CENPB ENSG00000125817 Centromere protein B, 80kDa 20 3783851-3786690 Predicted intracellular proteins Evidence at protein level CAB011626, HPA053507, HPA054405 Approved Validated Nuclear bodies Liver cancer:6.09e-4 (unfavourable) Expressed in all Expressed in all skin: 43.5 CENPN BM039, C16orf60, FLJ13607, FLJ22660 ENSG00000166451 Centromere protein N 16 81006498-81033114 Predicted intracellular proteins Evidence at protein level HPA052870 Supported Nucleus Pancreatic cancer:1.46e-5 (unfavourable), Renal cancer:4.86e-4 (unfavourable), Lung cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all prostate: 26.7 CENPT C16orf56, CENP-T, FLJ13111 ENSG00000102901 Centromere protein T 16 67828157-67847811 Predicted intracellular proteins Evidence at protein level HPA041220, HPA058036 Approved Validated Nuclear bodies Renal cancer:1.57e-7 (unfavourable), Pancreatic cancer:2.96e-4 (favourable) Expressed in all Expressed in all skin: 16.0 CEP104 CFAP256, GlyBP, KIAA0562, ROC22, RP1-286D6.4 ENSG00000116198 Centrosomal protein 104kDa 1 3812081-3857214 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA010126 Approved Renal cancer:1.70e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 35.5 CEP120 CCDC100, FLJ36090 ENSG00000168944 Centrosomal protein 120kDa 5 123344885-123423592 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028823, HPA051556 Uncertain Approved Microtubules
Cytosol Expressed in all Expressed in all testis: 29.6 CEP250 C-NAP1, CEP2 ENSG00000126001 Centrosomal protein 250kDa 20 35455164-35519280 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064875 Supported Centrosome Liver cancer:1.77e-7 (unfavourable), Renal cancer:1.97e-6 (unfavourable), Pancreatic cancer:9.27e-6 (favourable) Expressed in all Expressed in all testis: 35.1 CEP295 KIAA1731 ENSG00000166004 Centrosomal protein 295kDa 11 93661639-93730358 Predicted intracellular proteins Evidence at protein level HPA038595, HPA038596, HPA038597 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all testis: 22.2 CEP350 CAP350, KIAA0480 ENSG00000135837 Centrosomal protein 350kDa 1 179954738-180114880 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028355, HPA028357, HPA030845 Approved Supported Centrosome Renal cancer:1.02e-4 (unfavourable) Expressed in all Expressed in all testis: 44.8 CEP57 KIAA0092, Translokin, TSP57 ENSG00000166037 Centrosomal protein 57kDa 11 95789965-95832693 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018315 Approved Supported Microtubules
Cytosol Glioma:3.33e-4 (favourable) Expressed in all Expressed in all testis: 53.8 CEP57L1 bA487F23.2, C6orf182, MGC21731 ENSG00000183137 Centrosomal protein 57kDa-like 1 6 109095110-109163932 Predicted intracellular proteins Evidence at protein level HPA040378 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all testis: 47.4 CEP63 FLJ13386 ENSG00000182923 Centrosomal protein 63kDa 3 134485743-134575017 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA058154, HPA058313 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 83.5 CEP68 KIAA0582 ENSG00000011523 Centrosomal protein 68kDa 2 65056366-65087004 Predicted intracellular proteins Evidence at protein level HPA040493, HPA040620 Approved Supported Nucleus
Microtubule organizing center Renal cancer:3.93e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 28.5 CEP70 BITE, FLJ13036 ENSG00000114107 Centrosomal protein 70kDa 3 138494344-138594538 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036941, HPA036942 Supported Uncertain Nucleoplasm
Cytosol Prostate cancer:9.60e-5 (unfavourable), Cervical cancer:2.93e-4 (favourable) Expressed in all Expressed in all testis: 123.1 CEP83 CCDC41, NPHP18, NY-REN-58 ENSG00000173588 Centrosomal protein 83kDa 12 94306449-94459988 Predicted intracellular proteins Evidence at protein level HPA038161 Approved Approved Nucleus
Golgi apparatus Renal cancer:5.00e-10 (unfavourable), Prostate cancer:4.98e-4 (unfavourable) Expressed in all Expressed in all testis: 31.4 CEP95 CCDC45, DKFZp667E1824 ENSG00000258890 Centrosomal protein 95kDa 17 64506588-64542461 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023654, HPA052426, HPA052428, HPA061371 Approved Approved Nucleoplasm
Centrosome
Cytosol Liver cancer:2.52e-5 (unfavourable), Renal cancer:5.76e-5 (unfavourable), Head and neck cancer:5.78e-4 (favourable) Expressed in all Expressed in all endometrium: 27.7 CEPT1 ENSG00000134255 Choline/ethanolamine phosphotransferase 1 1 111139627-111185102 Enzymes, Predicted membrane proteins Evidence at protein level Glioma:6.43e-4 (favourable) Expressed in all Expressed in all spleen: 41.5 CERCAM CEECAM1, CerCAM, GLT25D3 ENSG00000167123 Cerebral endothelial cell adhesion molecule 9 128411751-128437351 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021657, HPA051595 Uncertain Approved Nucleus
Nucleoli
Cell Junctions Renal cancer:3.33e-16 (unfavourable), Urothelial cancer:3.30e-5 (unfavourable), Ovarian cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 156.0 CERK dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4 ENSG00000100422 Ceramide kinase 22 46684411-46738261 Enzymes, Predicted intracellular proteins Evidence at protein level HPA064699 Approved Vesicles Urothelial cancer:1.58e-4 (unfavourable), Pancreatic cancer:2.35e-4 (favourable), Endometrial cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all small intestine: 35.0 CERS2 FLJ10243, LASS2, SP260 ENSG00000143418 Ceramide synthase 2 1 150960583-150975004 Predicted membrane proteins Evidence at protein level HPA027262 Approved Supported Nuclear membrane
Endoplasmic reticulum Expressed in all Expressed in all liver: 408.6 CERS5 FLJ25304, LASS5, MGC45411, Trh4 ENSG00000139624 Ceramide synthase 5 12 50129306-50167533 Enzymes, Predicted membrane proteins Evidence at protein level HPA026589 Approved Approved Nucleus
Nucleoli Renal cancer:9.33e-11 (unfavourable), Liver cancer:4.63e-5 (unfavourable), Thyroid cancer:5.76e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 37.9 CERS6 LASS6 ENSG00000172292 Ceramide synthase 6 2 168455862-168775137 Predicted membrane proteins Evidence at protein level HPA044683, HPA063527 Approved Supported Nucleus Liver cancer:1.10e-4 (unfavourable), Endometrial cancer:7.31e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 43.4 CES2 CE-2, CES2A1, iCE ENSG00000172831 Carboxylesterase 2 16 66934444-66945096 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018897 Supported Approved Golgi apparatus
Cytosol Renal cancer:1.50e-5 (favourable) Expressed in all Expressed in all duodenum: 541.7 CETN2 CALT, CEN2 ENSG00000147400 Centrin, EF-hand protein, 2 X 152826973-152830777 Predicted intracellular proteins Evidence at protein level HPA028956 Uncertain Cervical cancer:7.54e-6 (favourable), Ovarian cancer:9.97e-4 (favourable) Expressed in all Expressed in all fallopian tube: 371.0 CFAP20 C16orf80, fSAP23, GTL3 ENSG00000070761 Cilia and flagella associated protein 20 16 58113588-58129450 Predicted intracellular proteins Evidence at protein level HPA018195 Uncertain Supported Nucleus Expressed in all Expressed in all fallopian tube: 53.8 CFAP36 CCDC104, MGC15407 ENSG00000163001 Cilia and flagella associated protein 36 2 55519604-55545879 Predicted intracellular proteins Evidence at protein level HPA008994, HPA017061 Approved Expressed in all Expressed in all testis: 237.8 CFAP97 DKFZp434F1728, hmw, KIAA1430 ENSG00000164323 Cilia and flagella associated protein 97 4 185159665-185209504 Predicted intracellular proteins Evidence at protein level HPA049446, HPA053335 Approved Supported Nucleoli
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 67.5 CFDP1 BCNT, CENP-29, CP27, p97, SWC5, Yeti ENSG00000153774 Craniofacial development protein 1 16 75293698-75433485 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041316, HPA048242 Approved Supported Nucleoplasm Head and neck cancer:9.63e-5 (unfavourable) Expressed in all Expressed in all testis: 112.0 CFL1 CFL ENSG00000172757 Cofilin 1 (non-muscle) 11 65823022-65862026 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033687, CAB037077, HPA053761 Approved Liver cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all appendix: 1266.2 CFL2 NEM7 ENSG00000165410 Cofilin 2 (muscle) 14 34706769-34714823 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037078, HPA045599 Supported Approved Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:2.16e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 242.8 CFLAR c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT ENSG00000003402 CASP8 and FADD-like apoptosis regulator 2 201116104-201176687 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA019044, CAB022157, CAB025216 Uncertain Supported Nucleus
Nuclear bodies
Plasma membrane
Cytosol Head and neck cancer:2.79e-4 (favourable) Expressed in all Expressed in all bone marrow: 160.5 CGGBP1 CGGBP, p20-CGGBP ENSG00000163320 CGG triplet repeat binding protein 1 3 88051944-88149885 Predicted intracellular proteins Evidence at protein level HPA035568, HPA037017 Supported Validated Nucleus Urothelial cancer:7.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 92.3 CGRRF1 CGR19, RNF197 ENSG00000100532 Cell growth regulator with ring finger domain 1 14 54509812-54539309 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002930 Uncertain Supported Nucleoplasm
Vesicles Renal cancer:2.57e-8 (favourable), Liver cancer:6.84e-4 (unfavourable) Expressed in all Expressed in all testis: 33.6 CH507-9B2.3 ENSG00000280071 21 5079294-5128425 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018517 Uncertain Mixed Expressed in all kidney: 147.3 CH507-9B2.5 ENSG00000275464 21 5130871-5154734 Predicted intracellular proteins Evidence at protein level HPA024573 Uncertain Approved Nucleoli
Cytosol Mixed Expressed in all cerebral cortex: 16.1 CHAMP1 C13orf8, CAMP, CHAMP, ZNF828 ENSG00000198824 Chromosome alignment maintaining phosphoprotein 1 13 114314513-114327328 Predicted intracellular proteins Evidence at protein level HPA006623, HPA008900 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all Expressed in all lymph node: 19.6 CHCHD1 C10orf34, FLJ25854 ENSG00000172586 Coiled-coil-helix-coiled-coil-helix domain containing 1 10 73782047-73783652 Predicted intracellular proteins Evidence at protein level HPA039046 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Mitochondria Urothelial cancer:5.42e-4 (favourable) Expressed in all Expressed in all epididymis: 61.6 CHCHD10 C22orf16, N27C7-4 ENSG00000250479 Coiled-coil-helix-coiled-coil-helix domain containing 10 22 23765834-23768443 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003440 Supported Supported Mitochondria Renal cancer:2.15e-7 (favourable) Expressed in all Expressed in all skeletal muscle: 220.7 CHCHD2 C7orf17 ENSG00000106153 Coiled-coil-helix-coiled-coil-helix domain containing 2 7 56101569-56106576 Predicted intracellular proteins Evidence at protein level HPA027407, HPA052510 Uncertain Validated Mitochondria Head and neck cancer:1.90e-5 (unfavourable), Liver cancer:9.41e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 588.3 CHCHD3 FLJ20420, Mic19, MINOS3, PPP1R22 ENSG00000106554 Coiled-coil-helix-coiled-coil-helix domain containing 3 7 132784868-133082088 Predicted intracellular proteins Evidence at protein level HPA042935 Supported Supported Mitochondria Renal cancer:1.15e-4 (favourable), Liver cancer:3.25e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 121.2 CHCHD4 FLJ31709, MIA40, TIMM40 ENSG00000163528 Coiled-coil-helix-coiled-coil-helix domain containing 4 3 14112077-14124870 Predicted intracellular proteins Evidence at protein level HPA034688, HPA063727 Uncertain Supported Mitochondria Renal cancer:8.63e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 30.7 CHCHD5 C2orf9, MGC11104, MIC14 ENSG00000125611 Coiled-coil-helix-coiled-coil-helix domain containing 5 2 112584240-112589275 Predicted intracellular proteins Evidence at protein level HPA038263 Approved Supported Mitochondria Expressed in all Expressed in all thyroid gland: 33.4 CHCHD6 CHCM1, MGC13016, Mic25, PPP1R23 ENSG00000159685 Coiled-coil-helix-coiled-coil-helix domain containing 6 3 126704220-126960406 Predicted intracellular proteins Evidence at protein level HPA047673, HPA051975 Approved Supported Mitochondria Renal cancer:6.76e-4 (favourable), Cervical cancer:7.46e-4 (favourable) Expressed in all Expressed in all testis: 48.8 CHCHD7 COX23, MGC2217 ENSG00000170791 Coiled-coil-helix-coiled-coil-helix domain containing 7 8 56211686-56218798 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050783 Approved Approved Cell Junctions
Aggresome Endometrial cancer:1.39e-6 (unfavourable), Renal cancer:9.47e-5 (favourable) Expressed in all Expressed in all ovary: 61.5 CHD1 ENSG00000153922 Chromodomain helicase DNA binding protein 1 5 98853985-98928957 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA022236 Approved Supported Nucleus
Nucleoli fibrillar center Renal cancer:7.25e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 44.4 CHD1L ALC1 ENSG00000131778 Chromodomain helicase DNA binding protein 1-like 1 147242641-147295766 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027789, HPA028670 Supported Supported Nucleoplasm Renal cancer:1.31e-9 (unfavourable), Liver cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all testis: 48.1 CHD2 DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614 ENSG00000173575 Chromodomain helicase DNA binding protein 2 15 92900189-93028005 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA060744, HPA060960 Supported Validated Nucleus Expressed in all Expressed in all bone marrow: 56.0 CHD3 Mi-2a, Mi2-ALPHA, ZFH ENSG00000170004 Chromodomain helicase DNA binding protein 3 17 7884806-7912760 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043368, HPA076524 Supported Approved Nucleus
Nucleoli
Microtubule organizing center Endometrial cancer:7.68e-5 (favourable), Colorectal cancer:2.43e-4 (unfavourable), Pancreatic cancer:8.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 83.9 CHD4 Mi-2b, Mi2-BETA ENSG00000111642 Chromodomain helicase DNA binding protein 4 12 6570083-6607476 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012008 Supported Validated Nucleus Liver cancer:6.03e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 117.2 CHD6 CHD5, dJ620E11.1, FLJ22369, KIAA1335, RIGB ENSG00000124177 Chromodomain helicase DNA binding protein 6 20 41402101-41618494 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015543 Approved Nucleus Lung cancer:3.42e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 31.0 CHD8 DUPLIN, HELSNF1, KIAA1564 ENSG00000100888 Chromodomain helicase DNA binding protein 8 14 21385194-21456126 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA052186 Supported Nucleoplasm Liver cancer:4.94e-4 (unfavourable), Ovarian cancer:8.35e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 46.2 CHD9 BC022889, FLJ12178, KIAA0308 ENSG00000177200 Chromodomain helicase DNA binding protein 9 16 53055033-53329150 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042053, HPA049420 Approved Approved Plasma membrane
Cytosol Renal cancer:1.84e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.8 CHERP DAN16, ERPROT213-21 ENSG00000085872 Calcium homeostasis endoplasmic reticulum protein 19 16517889-16542530 Predicted intracellular proteins Evidence at protein level HPA050647 Uncertain Expressed in all Expressed in all cerebral cortex: 22.2 CHFR FLJ10796, RNF196 ENSG00000072609 Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 12 132822187-132956304 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045768 Uncertain Nuclear bodies
Microtubules Renal cancer:4.21e-9 (unfavourable) Expressed in all Expressed in all testis: 22.8 CHIC2 BTL ENSG00000109220 Cysteine-rich hydrophobic domain 2 4 54009789-54064690 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026782 Uncertain Renal cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all testis: 62.9 CHID1 FLJ42707, MGC3234 ENSG00000177830 Chitinase domain containing 1 11 867860-915058 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039374 Uncertain Uncertain Nucleoplasm
Intermediate filaments Endometrial cancer:6.76e-4 (favourable) Expressed in all Expressed in all epididymis: 108.1 CHKA CHK, CKI ENSG00000110721 Choline kinase alpha 11 68052859-68121444 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024153, CAB072803 Approved Approved Endoplasmic reticulum Liver cancer:7.75e-4 (unfavourable) Expressed in all Expressed in all testis: 135.2 CHM DXS540, REP-1, TCD ENSG00000188419 Choroideremia (Rab escort protein 1) X 85861180-86047562 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003231, CAB016171 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 21.6 CHMP1A CHMP1, KIAA0047, PCOLN3, PRSM1, Vps46A ENSG00000131165 Charged multivesicular body protein 1A 16 89644431-89657845 Disease related genes, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all small intestine: 53.1 CHMP1B C18orf2, CHMP1.5, Vps46B ENSG00000255112 Charged multivesicular body protein 1B 18 11851396-11854449 Predicted intracellular proteins Evidence at protein level HPA061997, HPA062896 Supported Supported Nucleus
Midbody Renal cancer:7.37e-8 (favourable) Expressed in all Expressed in all thyroid gland: 86.7 CHMP2A BC-2, CHMP2, VPS2, VPS2A ENSG00000130724 Charged multivesicular body protein 2A 19 58551566-58555124 Predicted intracellular proteins Evidence at protein level HPA041153, HPA042031 Supported Approved Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 191.1 CHMP2B CHMP2.5, DKFZP564O123, VPS2B ENSG00000083937 Charged multivesicular body protein 2B 3 87227271-87255548 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035069, HPA052754 Uncertain Supported Cytosol Renal cancer:1.74e-6 (favourable), Pancreatic cancer:2.11e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 78.2 CHMP3 CGI-149, NEDF, VPS24 ENSG00000115561 Charged multivesicular body protein 3 2 86503431-86563479 Predicted intracellular proteins Evidence at protein level HPA015673 Approved Liver cancer:3.92e-5 (unfavourable), Renal cancer:5.32e-4 (favourable), Pancreatic cancer:7.39e-4 (unfavourable) Expressed in all Expressed in all endometrium: 113.5 CHMP4A C14orf123, HSPC134, VPS32A ENSG00000254505 Charged multivesicular body protein 4A 14 24209583-24213869 Predicted intracellular proteins Evidence at protein level HPA068473 Approved Renal cancer:3.91e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 128.0 CHMP4B C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B ENSG00000101421 Charged multivesicular body protein 4B 20 33811304-33854366 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041401, HPA051751 Supported Liver cancer:5.10e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 140.8 CHMP5 C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60 ENSG00000086065 Charged multivesicular body protein 5 9 33264879-33282069 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033874, HPA042883, HPA056437 Approved Supported Microtubules
Midbody
Cytosol Renal cancer:2.87e-7 (favourable) Expressed in all Expressed in all thyroid gland: 127.0 CHMP6 FLJ11749, VPS20 ENSG00000176108 Charged multivesicular body protein 6 17 80991598-81009517 Predicted intracellular proteins Evidence at protein level HPA023001, HPA024460 Approved Pancreatic cancer:9.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 28.1 CHORDC1 CHP1 ENSG00000110172 Cysteine and histidine-rich domain (CHORD) containing 1 11 90201160-90223364 Predicted intracellular proteins Evidence at protein level HPA041040 Approved Supported Cytosol Liver cancer:4.93e-7 (unfavourable), Renal cancer:1.88e-4 (unfavourable) Expressed in all Expressed in all placenta: 31.2 CHP1 CHP, p22, p24, Sid470p, SLC9A1BP ENSG00000187446 Calcineurin-like EF-hand protein 1 15 41230839-41281890 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006616 Approved Approved Vesicles Renal cancer:2.79e-6 (favourable), Liver cancer:4.07e-6 (favourable), Endometrial cancer:9.63e-4 (favourable) Expressed in all Expressed in all colon: 113.0 CHPF CHSY2, CSS2 ENSG00000123989 Chondroitin polymerizing factor 2 219538947-219543787 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035123 Approved Supported Vesicles
Centrosome
Cytosol Cervical cancer:1.57e-4 (unfavourable), Head and neck cancer:1.68e-4 (unfavourable), Urothelial cancer:2.96e-4 (unfavourable), Glioma:9.56e-4 (unfavourable) Expressed in all Expressed in all testis: 77.4 CHPF2 ChSy-3, CSGlcA-T, KIAA1402 ENSG00000033100 Chondroitin polymerizing factor 2 7 151232489-151238827 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020992 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:2.51e-4 (favourable), Liver cancer:9.47e-4 (unfavourable) Expressed in all Expressed in all appendix: 24.0 CHPT1 CPT1 ENSG00000111666 Choline phosphotransferase 1 12 101696947-101744140 Enzymes, Predicted membrane proteins Evidence at protein level HPA067643 Approved Approved Vesicles Thyroid cancer:7.41e-4 (favourable) Expressed in all Expressed in all breast: 124.5 CHRAC1 CHRAC15, YCL1 ENSG00000104472 Chromatin accessibility complex 1 8 140511298-140517137 Predicted intracellular proteins Evidence at protein level HPA059008 Approved Nucleus Liver cancer:4.88e-5 (unfavourable), Endometrial cancer:2.28e-4 (unfavourable), Pancreatic cancer:5.43e-4 (unfavourable), Ovarian cancer:9.72e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.9 CHRNB1 CHRNB ENSG00000170175 Cholinergic receptor, nicotinic, beta 1 (muscle) 17 7445061-7457707 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA005822, CAB011200 Approved Expressed in all Expressed in all skeletal muscle: 43.9 CHST12 C4S-2, C4ST2 ENSG00000136213 Carbohydrate (chondroitin 4) sulfotransferase 12 7 2403560-2448483 Enzymes, Predicted membrane proteins Evidence at protein level HPA041680 Approved Approved Golgi apparatus Pancreatic cancer:1.32e-5 (favourable) Expressed in all Expressed in all spleen: 16.4 CHST14 D4ST-1, D4ST1, HD4ST ENSG00000169105 Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 15 40470998-40474571 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA057697, HPA071601 Approved Approved Vesicles Expressed in all Expressed in all placenta: 38.5 CHST15 BRAG, GALNAC4S-6ST, KIAA0598 ENSG00000182022 Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 10 124007666-124093607 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017584 Approved Approved Centrosome
Cytosol Renal cancer:2.22e-7 (unfavourable) Expressed in all Expressed in all ovary: 45.4 CHSY1 CSS1, KIAA0990 ENSG00000131873 Chondroitin sulfate synthase 1 15 101175723-101251932 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA048902 Uncertain Renal cancer:6.33e-5 (unfavourable) Expressed in all Expressed in all placenta: 64.3 CHTF8 CTF8, DERPC, FLJ20400 ENSG00000168802 Chromosome transmission fidelity factor 8 16 69118010-69132584 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051872, HPA065522 Approved Validated Nucleoplasm Renal cancer:3.59e-9 (favourable) Expressed in all Expressed in all fallopian tube: 111.5 CHTOP C1orf77, DKFZP547E1010, FOP, SRAG ENSG00000160679 Chromatin target of PRMT1 1 153633982-153646306 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028647, HPA030540 Approved Validated Nuclear speckles Renal cancer:2.02e-4 (unfavourable), Urothelial cancer:2.69e-4 (favourable), Melanoma:4.08e-4 (unfavourable), Liver cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all endometrium: 61.7 CHUK IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 ENSG00000213341 Conserved helix-loop-helix ubiquitous kinase 10 100188298-100229619 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001402, CAB004240, CAB018564 Approved Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 22.8 CHURC1 C14orf52, FLJ33064, My015 ENSG00000258289 Churchill domain containing 1 14 64914361-64944591 Predicted intracellular proteins Evidence at protein level HPA040072 Approved Approved Cytosol Expressed in all Expressed in all smooth muscle: 69.9 CIAO1 CIA1, WDR39 ENSG00000144021 Cytosolic iron-sulfur assembly component 1 2 96266132-96273349 Predicted intracellular proteins Evidence at protein level HPA017882 Uncertain Approved Nucleoplasm
Cytosol Endometrial cancer:4.13e-5 (unfavourable), Liver cancer:1.14e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.6 CIAPIN1 Anamorsin ENSG00000005194 Cytokine induced apoptosis inhibitor 1 16 57428169-57447528 Predicted intracellular proteins Evidence at protein level HPA041350, HPA042182 Supported Supported Mitochondria Head and neck cancer:4.35e-4 (unfavourable), Renal cancer:4.42e-4 (favourable) Expressed in all Expressed in all testis: 128.4 CIB1 CALMYRIN, CIB, KIP, SIP2-28 ENSG00000185043 Calcium and integrin binding 1 (calmyrin) 15 90229975-90234047 Predicted intracellular proteins Evidence at protein level CAB012991, HPA048825 Approved Supported Nucleoplasm
Plasma membrane Endometrial cancer:2.26e-5 (favourable) Expressed in all Expressed in all fallopian tube: 204.7 CIC KIAA0306 ENSG00000079432 Capicua transcriptional repressor 19 42268537-42295797 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026388, HPA044341, HPA064725 Approved Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 55.0 CIDEB ENSG00000136305 Cell death-inducing DFFA-like effector b 14 24305096-24311430 Predicted intracellular proteins Evidence at protein level HPA001272 Uncertain Mixed Expressed in all liver: 182.8 CINP MGC849 ENSG00000100865 Cyclin-dependent kinase 2 interacting protein 14 102341102-102362916 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all testis: 47.9 CIPC KIAA1737 ENSG00000198894 CLOCK-interacting pacemaker 14 77098097-77117287 Predicted intracellular proteins Evidence at protein level HPA000644 Supported Nucleus
Nucleoli
Cytosol Renal cancer:1.77e-10 (favourable) Expressed in all Expressed in all cerebral cortex: 54.5 CIR1 CIR ENSG00000138433 Corepressor interacting with RBPJ, 1 2 174348022-174395715 Predicted intracellular proteins Evidence at protein level HPA015784 Supported Nuclear speckles Renal cancer:1.04e-7 (unfavourable), Urothelial cancer:2.04e-5 (favourable), Liver cancer:2.52e-4 (unfavourable), Endometrial cancer:9.56e-4 (unfavourable), Ovarian cancer:9.80e-4 (favourable) Expressed in all Expressed in all testis: 57.0 CIRBP CIRP ENSG00000099622 Cold inducible RNA binding protein 19 1259384-1274880 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060537 Supported Nucleus
Nucleoli Renal cancer:3.65e-7 (favourable), Endometrial cancer:1.36e-4 (favourable), Lung cancer:2.50e-4 (favourable), Pancreatic cancer:2.69e-4 (favourable), Cervical cancer:3.63e-4 (favourable) Expressed in all Expressed in all ovary: 1040.0 CIRH1A CIRHIN, FLJ14728, KIAA1988, NAIC, TEX292, UTP4 ENSG00000141076 Cirrhosis, autosomal recessive 1A (cirhin) 16 69131291-69231130 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041139, HPA043542 Approved Supported Nucleoli fibrillar center Liver cancer:8.18e-7 (unfavourable), Ovarian cancer:2.88e-5 (favourable), Head and neck cancer:9.05e-5 (unfavourable) Expressed in all Expressed in all testis: 51.4 CISD2 ERIS, Miner1, NAF-1, WFS2, ZCD2 ENSG00000145354 CDGSH iron sulfur domain 2 4 102868978-102889242 Disease related genes, Predicted membrane proteins Evidence at protein level HPA015914 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 61.7 CITED2 MRG1 ENSG00000164442 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 6 139371807-139374620 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016157, CAB069879 Supported Supported Nucleoplasm Stomach cancer:3.33e-4 (unfavourable), Renal cancer:3.40e-4 (favourable) Expressed in all Expressed in all thyroid gland: 376.7 CIZ1 LSFR1, ZNF356 ENSG00000148337 CDKN1A interacting zinc finger protein 1 9 128166064-128204383 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020380, HPA020387 Uncertain Validated Nucleoplasm Liver cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all testis: 94.3 CKAP4 CLIMP-63, ERGIC-63, P63 ENSG00000136026 Cytoskeleton-associated protein 4 12 106237877-106304279 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000278, HPA000792, HPA001225 Supported Uncertain Nuclear speckles
Cytosol
Cytoplasmic bodies Renal cancer:0.00e+0 (unfavourable), Liver cancer:6.61e-5 (unfavourable), Lung cancer:5.61e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 78.2 CKAP5 ch-TOG, KIAA0097, TOG, TOGp ENSG00000175216 Cytoskeleton associated protein 5 11 46743048-46846308 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039377, HPA040375 Supported Approved Nucleoli
Plasma membrane
Cytosol Liver cancer:1.03e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 66.4 CKB CKBB ENSG00000166165 Creatine kinase, brain 14 103519659-103523111 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001254, CAB047313 Supported Supported Cytosol Renal cancer:4.02e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 476.4 CKLF C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1 ENSG00000217555 Chemokine-like factor 16 66552563-66566251 Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level HPA062779 Approved Vesicles Renal cancer:1.06e-9 (unfavourable), Liver cancer:5.67e-5 (unfavourable), Thyroid cancer:2.22e-4 (favourable) Expressed in all Expressed in all testis: 91.2 CKS1B CKS1, ckshs1 ENSG00000173207 CDC28 protein kinase regulatory subunit 1B 1 154974653-154979249 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA003424, HPA030762 Approved Supported Approved Nucleus
Vesicles
Mitochondria
Cytosol Renal cancer:6.03e-7 (unfavourable), Liver cancer:2.94e-5 (unfavourable), Melanoma:3.12e-5 (unfavourable), Thyroid cancer:4.87e-4 (favourable), Pancreatic cancer:6.13e-4 (unfavourable), Endometrial cancer:7.89e-4 (unfavourable) Expressed in all Expressed in all lymph node: 86.0 CLASP1 KIAA0622, MAST1 ENSG00000074054 Cytoplasmic linker associated protein 1 2 121337776-121649587 Predicted intracellular proteins Evidence at protein level HPA065219 Uncertain Renal cancer:6.50e-4 (unfavourable) Expressed in all Expressed in all testis: 34.4 CLASRP CLASP, SFRS16, SWAP2 ENSG00000104859 CLK4-associating serine/arginine rich protein 19 45039040-45070956 Predicted intracellular proteins Evidence at protein level HPA060469, HPA062455 Approved Validated Nucleus Renal cancer:1.69e-8 (unfavourable), Urothelial cancer:1.02e-5 (favourable), Colorectal cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 11.9 CLCC1 MCLC ENSG00000121940 Chloride channel CLIC-like 1 1 108929508-108963457 Predicted membrane proteins, Transporters Evidence at protein level HPA009087, HPA013210 Supported Validated Endoplasmic reticulum Colorectal cancer:1.33e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 38.0 CLCN3 ClC-3, CLC3 ENSG00000109572 Chloride channel, voltage-sensitive 3 4 169612633-169723673 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044723 Approved Approved Cytosol Renal cancer:1.10e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 104.4 CLCN7 CLC-7, CLC7, OPTA2, PPP1R63 ENSG00000103249 Chloride channel, voltage-sensitive 7 16 1444934-1475580 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA043019, HPA043586 Supported Supported Nucleoplasm Testis cancer:3.21e-4 (unfavourable), Head and neck cancer:5.23e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 40.4 CLDN12 ENSG00000157224 Claudin 12 7 90383721-90513402 Predicted membrane proteins Evidence at protein level HPA026945 Approved Cervical cancer:6.36e-4 (unfavourable) Expressed in all Expressed in all prostate: 40.8 CLDND1 C3orf4 ENSG00000080822 Claudin domain containing 1 3 98497912-98523066 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA029841 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:5.84e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 400.9 CLEC16A Gop-1, KIAA0350 ENSG00000038532 C-type lectin domain family 16, member A 16 10944488-11182189 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035814, HPA035815, HPA061385 Approved Approved Nucleus
Vesicles Renal cancer:2.92e-6 (favourable) Expressed in all Expressed in all testis: 60.2 CLIC1 NCC27, p64CLCP ENSG00000213719 Chloride intracellular channel 1 6 31730581-31739763 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB020825, CAB040557 Supported Supported Cytosol Liver cancer:8.90e-7 (unfavourable), Renal cancer:8.11e-5 (unfavourable) Expressed in all Expressed in all rectum: 71.3 CLIC4 CLIC4L, DKFZP566G223, H1, huH1, P64H1 ENSG00000169504 Chloride intracellular channel 4 1 24745357-24844324 Predicted intracellular proteins, Transporters Evidence at protein level HPA008019, HPA060804 Supported Supported Cytosol Renal cancer:1.48e-5 (favourable), Cervical cancer:8.31e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 393.9 CLINT1 CLINT, ENTH, EPNR, KIAA0171 ENSG00000113282 Clathrin interactor 1 5 157785743-157859175 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043280, HPA056947 Supported Supported Nucleoplasm
Vesicles Renal cancer:8.88e-5 (favourable), Colorectal cancer:2.95e-4 (favourable), Thyroid cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 167.9 CLIP1 CLIP, CLIP-170, CLIP170, CYLN1, RSN ENSG00000130779 CAP-GLY domain containing linker protein 1 12 122271432-122422632 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004399, HPA026678 Approved Supported Microtubule ends
Cytosol Expressed in all Expressed in all parathyroid gland: 156.2 CLIP4 FLJ21069, RSNL2 ENSG00000115295 CAP-GLY domain containing linker protein family, member 4 2 29097705-29189643 Predicted intracellular proteins Evidence at protein level HPA043366, HPA056246 Uncertain Validated Vesicles Renal cancer:1.83e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 55.6 CLK1 ENSG00000013441 CDC-like kinase 1 2 200853009-200864744 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033141, HPA062405 Approved Supported Nucleoplasm
Nuclear membrane Urothelial cancer:2.28e-4 (favourable) Expressed in all Expressed in all bone marrow: 113.8 CLK2 clk2 ENSG00000176444 CDC-like kinase 2 1 155262868-155278491 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055366, HPA059507 Approved Validated Nucleoplasm
Nuclear bodies Renal cancer:2.95e-9 (unfavourable), Liver cancer:2.82e-4 (unfavourable), Colorectal cancer:3.77e-4 (unfavourable), Urothelial cancer:5.43e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.3 CLK3 clk3 ENSG00000179335 CDC-like kinase 3 15 74598500-74645414 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046817 Approved Supported Nucleoplasm
Intermediate filaments Colorectal cancer:2.05e-6 (unfavourable), Prostate cancer:5.92e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 71.9 CLK4 ENSG00000113240 CDC-like kinase 4 5 178602664-178630615 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043746 Approved Approved Actin filaments Expressed in all Expressed in all testis: 22.4 CLN3 BTS, JNCL ENSG00000188603 Ceroid-lipofuscinosis, neuronal 3 16 28477279-28495575 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063280 Uncertain Expressed in all Expressed in all placenta: 54.9 CLN5 ENSG00000102805 Ceroid-lipofuscinosis, neuronal 5 13 76990660-77002517 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041788 Approved Renal cancer:1.52e-9 (favourable) Expressed in all Expressed in all thyroid gland: 141.2 CLN6 FLJ20561, HsT18960, nclf ENSG00000128973 Ceroid-lipofuscinosis, neuronal 6, late infantile, variant 15 68206992-68257211 Disease related genes, Predicted membrane proteins Evidence at protein level HPA066046, HPA074162 Approved Approved Vesicles Renal cancer:4.87e-4 (favourable) Expressed in all Expressed in all appendix: 23.0 CLN8 C8orf61, EPMR, FLJ39417 ENSG00000182372 Ceroid-lipofuscinosis, neuronal 8 8 1755778-1786572 Disease related genes, Predicted membrane proteins Evidence at protein level Renal cancer:4.36e-8 (favourable) Expressed in all Expressed in all placenta: 10.8 CLNS1A CLCI, ICln ENSG00000074201 Chloride channel, nucleotide-sensitive, 1A 11 77514936-77637805 Predicted intracellular proteins, Transporters Evidence at protein level CAB017840, HPA031707, HPA031708, HPA032045 Approved Supported Nucleus
Microtubules
Cytosol Renal cancer:5.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 131.3 CLP1 hClp1, HEAB ENSG00000172409 Cleavage and polyadenylation factor I subunit 1 11 57648992-57661868 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA057770 Supported Supported Nucleoplasm Expressed in all Expressed in all bone marrow: 17.1 CLPP ENSG00000125656 Caseinolytic mitochondrial matrix peptidase proteolytic subunit 19 6361452-6368908 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA010649 Supported Validated Mitochondria Pancreatic cancer:6.50e-4 (favourable) Expressed in all Expressed in all appendix: 50.0 CLPTM1 ENSG00000104853 Cleft lip and palate associated transmembrane protein 1 19 44954585-44993341 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068702 Approved Nuclear membrane
Microtubule organizing center Expressed in all Expressed in all parathyroid gland: 127.5 CLPTM1L CRR9, FLJ14400 ENSG00000049656 CLPTM1-like 5 1317744-1345099 Predicted membrane proteins Evidence at protein level HPA014791 Approved Approved Endoplasmic reticulum Liver cancer:3.75e-4 (unfavourable) Expressed in all Expressed in all testis: 54.1 CLPX ENSG00000166855 Caseinolytic mitochondrial matrix peptidase chaperone subunit 15 65148219-65185342 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040262, HPA048199 Approved Validated Mitochondria Renal cancer:1.93e-9 (favourable) Expressed in all Expressed in all skin: 17.7 CLSTN1 CDHR12, CSTN1, KIAA0911 ENSG00000171603 Calsyntenin 1 1 9729026-9824526 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA012412 Approved Renal cancer:4.10e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 382.9 CLTA Lca ENSG00000122705 Clathrin, light chain A 9 36190856-36304781 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002665, HPA050918, HPA054667 Supported Supported Endosomes
Lysosomes Liver cancer:9.46e-5 (unfavourable), Thyroid cancer:1.01e-4 (favourable), Breast cancer:5.64e-4 (favourable) Expressed in all Expressed in all placenta: 176.8 CLTB Lcb ENSG00000175416 Clathrin, light chain B 5 176392455-176416569 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003692, HPA036458 Approved Supported Vesicles
Plasma membrane
Cytosol Renal cancer:7.89e-5 (unfavourable) Expressed in all Expressed in all esophagus: 243.7 CLTC CLTCL2, Hc ENSG00000141367 Clathrin, heavy chain (Hc) 17 59619689-59696956 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010389, CAB011571, CAB017155, HPA059143 Approved Validated Endosomes
Lysosomes Urothelial cancer:2.02e-4 (unfavourable), Liver cancer:5.54e-4 (unfavourable), Cervical cancer:7.35e-4 (unfavourable), Colorectal cancer:7.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 358.1 CLU APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2 ENSG00000120885 Clusterin 8 27596917-27615031 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000476, HPA000572, CAB016253 Uncertain Thyroid cancer:7.66e-5 (favourable) Expressed in all Expressed in all epididymis: 10967.7 CLUAP1 CFAP22, FAP22, FLJ13297, IFT38, KIAA0643 ENSG00000103351 Clusterin associated protein 1 16 3500924-3539048 Predicted intracellular proteins Evidence at protein level HPA036976, HPA044191 Uncertain Supported Nucleoplasm
Vesicles Endometrial cancer:3.01e-4 (favourable) Expressed in all Expressed in all testis: 71.7 CLUH CLU1, KIAA0664 ENSG00000132361 Clustered mitochondria (cluA/CLU1) homolog 17 2689386-2712663 Predicted intracellular proteins Evidence at protein level HPA031505, HPA044346 Uncertain Supported Nuclear bodies
Vesicles Renal cancer:1.92e-5 (favourable) Expressed in all Expressed in all esophagus: 50.9 CLYBL CLB ENSG00000125246 Citrate lyase beta like 13 99606669-99897134 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039959, HPA040691 Supported Approved Cytosol Renal cancer:6.66e-16 (favourable) Expressed in all Expressed in all kidney: 66.9 CMAS ENSG00000111726 Cytidine monophosphate N-acetylneuraminic acid synthetase 12 22046174-22065674 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039905 Supported Uncertain Nucleoli
Cytosol Renal cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all testis: 127.6 CMBL FLJ23617 ENSG00000164237 Carboxymethylenebutenolidase homolog (Pseudomonas) 5 10275875-10308026 Predicted intracellular proteins Evidence at protein level HPA036571 Uncertain Ovarian cancer:1.99e-4 (favourable) Expressed in all Expressed in all kidney: 313.7 CMC1 C3orf68, MGC61571 ENSG00000187118 C-x(9)-C motif containing 1 3 28241584-28325142 Predicted intracellular proteins Evidence at protein level HPA043333 Approved Urothelial cancer:5.52e-4 (favourable), Renal cancer:6.81e-4 (favourable) Expressed in all Expressed in all kidney: 33.3 CMC2 C16orf61, DC13, MGC45036 ENSG00000103121 C-x(9)-C motif containing 2 16 80966448-81020270 Predicted intracellular proteins Evidence at protein level HPA006871, CAB026396 Approved Supported Mitochondria Renal cancer:2.64e-5 (favourable) Expressed in all Expressed in all testis: 84.4 CMC4 MTCP1, MTCP1NB, p8, P8MTCP1 ENSG00000182712 C-x(9)-C motif containing 4 X 155061622-155071362 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045866 Approved Supported Mitochondria Not detected Expressed in all heart muscle: 20.7 CMIP ENSG00000153815 C-Maf inducing protein 16 81445170-81711762 Predicted intracellular proteins Evidence at protein level HPA054424, HPA066710 Approved Supported Nucleoplasm
Cytosol Lung cancer:9.47e-7 (unfavourable), Thyroid cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 87.6 CMPK1 CMPK, UMP-CMPK ENSG00000162368 Cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 1 47333797-47378839 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA053730, HPA058604 Approved Supported Nucleus Glioma:8.67e-4 (favourable) Expressed in all Expressed in all small intestine: 172.6 CMSS1 C3orf26, MGC4308 ENSG00000184220 Cms1 ribosomal small subunit homolog (yeast) 3 99817834-100178603 Predicted intracellular proteins Evidence at protein level HPA042820 Uncertain Approved Nucleus
Nuclear membrane
Nucleoli
Mitochondria Liver cancer:5.92e-10 (unfavourable), Endometrial cancer:3.15e-6 (unfavourable), Prostate cancer:3.10e-4 (unfavourable) Expressed in all Expressed in all testis: 56.0 CMTM3 BNAS2, CKLFSF3, FLJ31762 ENSG00000140931 CKLF-like MARVEL transmembrane domain containing 3 16 66603874-66613892 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013870 Approved Nucleoplasm Renal cancer:4.42e-6 (unfavourable), Stomach cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all testis: 69.3 CMTM6 CKLFSF6, FLJ20396 ENSG00000091317 CKLF-like MARVEL transmembrane domain containing 6 3 32481312-32503408 Predicted membrane proteins Evidence at protein level HPA026980 Approved Approved Intermediate filaments
Cytosol Expressed in all Expressed in all fallopian tube: 236.7 CMTR1 FTSJD2, ISG95, KIAA0082, MTr1 ENSG00000137200 Cap methyltransferase 1 6 37433219-37482827 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029954, HPA029979, HPA029980 Supported Validated Nucleoplasm
Cytosol Endometrial cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all testis: 85.4 CNBP CNBP1, DM2, RNF163, ZCCHC22, ZNF9 ENSG00000169714 CCHC-type zinc finger, nucleic acid binding protein 3 129169484-129183922 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063097 Supported Nucleus
Cytosol Pancreatic cancer:3.51e-4 (unfavourable) Expressed in all Expressed in all ovary: 473.3 CNDP2 CN2, CPGL, FLJ10830, HsT2298, PEPA ENSG00000133313 CNDP dipeptidase 2 (metallopeptidase M20 family) 18 74495816-74523454 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026196, HPA036898, HPA036899 Supported Validated Nucleoplasm
Cytosol Renal cancer:3.50e-6 (favourable) Expressed in all Expressed in all kidney: 341.1 CNIH1 CNIH, CNIL, TGAM77 ENSG00000100528 Cornichon family AMPA receptor auxiliary protein 1 14 54423560-54441431 Predicted membrane proteins, Transporters Evidence at protein level HPA002544 Approved Approved Vesicles Urothelial cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all liver: 118.5 CNIH4 HSPC163 ENSG00000143771 Cornichon family AMPA receptor auxiliary protein 4 1 224356850-224379459 Predicted membrane proteins Evidence at protein level HPA044268 Approved Renal cancer:4.27e-6 (unfavourable), Head and neck cancer:1.72e-4 (unfavourable), Pancreatic cancer:4.61e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 27.1 CNN2 ENSG00000064666 Calponin 2 19 1026581-1039068 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049095 Approved Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:4.70e-7 (unfavourable) Expressed in all Expressed in all lymph node: 211.5 CNN3 ENSG00000117519 Calponin 3, acidic 1 94896949-94927278 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009849, HPA051237 Supported Validated Actin filaments
Cytosol Urothelial cancer:1.99e-4 (unfavourable) Expressed in all Expressed in all placenta: 342.5 CNNM3 ACDP3 ENSG00000168763 Cyclin and CBS domain divalent metal cation transport mediator 3 2 96816245-96833911 Predicted membrane proteins, Transporters Evidence at protein level HPA016711 Supported Approved Cytosol Expressed in all Expressed in all parathyroid gland: 42.9 CNNM4 ACDP4, KIAA1592 ENSG00000158158 Cyclin and CBS domain divalent metal cation transport mediator 4 2 96760902-96811891 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA017732 Supported Uncertain Plasma membrane
Actin filaments Ovarian cancer:8.75e-4 (unfavourable), Endometrial cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all rectum: 37.5 CNOT1 AD-005, CDC39, KIAA1007, NOT1, NOT1H ENSG00000125107 CCR4-NOT transcription complex, subunit 1 16 58519951-58629886 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046577, HPA049664 Approved Supported Cytosol Expressed in all Expressed in all testis: 206.0 CNOT10 FLJ12890, FLJ13165 ENSG00000182973 CCR4-NOT transcription complex, subunit 10 3 32685145-32773875 Predicted intracellular proteins Evidence at protein level HPA035614, HPA041450 Approved Approved Nucleoplasm
Centrosome
Cytosol Liver cancer:1.03e-6 (unfavourable) Expressed in all Expressed in all testis: 71.6 CNOT11 C2orf29, C40 ENSG00000158435 CCR4-NOT transcription complex, subunit 11 2 101252802-101270316 Predicted intracellular proteins Evidence at protein level HPA069823 Supported Nucleoplasm Renal cancer:8.33e-6 (unfavourable), Liver cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all testis: 51.8 CNOT2 CDC36, NOT2, NOT2H ENSG00000111596 CCR4-NOT transcription complex, subunit 2 12 70242994-70354993 Predicted intracellular proteins Evidence at protein level HPA067711 Approved Approved Nucleus
Cytosol Renal cancer:8.63e-5 (unfavourable), Liver cancer:2.21e-4 (unfavourable), Melanoma:6.86e-4 (unfavourable) Expressed in all Expressed in all skin: 54.3 CNOT3 KIAA0691, LENG2, NOT3, NOT3H ENSG00000088038 CCR4-NOT transcription complex, subunit 3 19 54137728-54155681 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA006408 Approved Approved Cytosol Liver cancer:2.22e-4 (unfavourable), Renal cancer:2.77e-4 (unfavourable) Expressed in all Expressed in all testis: 36.1 CNOT4 CLONE243, NOT4, NOT4H ENSG00000080802 CCR4-NOT transcription complex, subunit 4 7 135361795-135510127 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005737 Approved Renal cancer:7.67e-6 (favourable), Liver cancer:1.19e-4 (unfavourable), Ovarian cancer:1.61e-4 (favourable) Expressed in all Expressed in all testis: 33.2 CNOT6 CCR4, Ccr4a, KIAA1194 ENSG00000113300 CCR4-NOT transcription complex, subunit 6 5 180494412-180578405 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044568 Approved Approved Cytosol Liver cancer:3.61e-7 (unfavourable) Expressed in all Expressed in all testis: 25.0 CNOT6L Ccr4b, DKFZp434K098 ENSG00000138767 CCR4-NOT transcription complex, subunit 6-like 4 77713387-77819615 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042688 Uncertain Supported Cytosol Renal cancer:1.69e-4 (favourable) Expressed in all Expressed in all lymph node: 44.2 CNOT7 CAF1 ENSG00000198791 CCR4-NOT transcription complex, subunit 7 8 17224964-17246878 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069543 Supported Nuclear bodies Colorectal cancer:4.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 109.5 CNOT8 CAF1, CALIF, hCAF1, POP2 ENSG00000155508 CCR4-NOT transcription complex, subunit 8 5 154857553-154876793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051398 Approved Liver cancer:5.33e-4 (unfavourable), Urothelial cancer:6.41e-4 (favourable) Expressed in all Expressed in all bone marrow: 74.8 CNPPD1 C2orf24, CGI-57 ENSG00000115649 Cyclin Pas1/PHO80 domain containing 1 2 219171897-219178106 Predicted membrane proteins Evidence at transcript level HPA049303 Uncertain Renal cancer:1.62e-10 (favourable), Liver cancer:2.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 86.9 CNPY2 Cnpy2, HP10390, TMEM4, ZSIG9 ENSG00000257727 Canopy FGF signaling regulator 2 12 56309842-56316336 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038465, HPA038466 Supported Supported Cytosol Renal cancer:2.32e-8 (unfavourable), Pancreatic cancer:8.37e-4 (favourable) Expressed in all Expressed in all epididymis: 85.9 CNPY3 CAG4A, TNRC5 ENSG00000137161 Canopy FGF signaling regulator 3 6 42929192-42939287 Predicted secreted proteins Evidence at protein level HPA016560 Uncertain Renal cancer:9.85e-6 (unfavourable), Colorectal cancer:3.03e-5 (unfavourable) Expressed in all Expressed in all spleen: 105.0 CNST C1orf71, FLJ32001, PPP1R64 ENSG00000162852 Consortin, connexin sorting protein 1 246566444-246668584 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007225, HPA007226 Approved Supported Vesicles Expressed in all Expressed in all cerebral cortex: 26.4 CNTROB LIP8, PP1221 ENSG00000170037 Centrobin, centrosomal BRCA2 interacting protein 17 7932101-7949918 Predicted intracellular proteins Evidence at protein level HPA023319, HPA023320, HPA023321, HPA023325 Approved Supported Centrosome
Cytosol Liver cancer:9.88e-4 (unfavourable) Expressed in all Expressed in all testis: 91.0 COA1 C7orf44, FLJ10803, MITRAC15 ENSG00000106603 Cytochrome c oxidase assembly factor 1 homolog 7 43608456-43729717 Predicted membrane proteins Evidence at protein level HPA011944 Approved Supported Mitochondria Liver cancer:7.84e-5 (unfavourable) Expressed in all Expressed in all lymph node: 36.9 COA3 CCDC56, HSPC009, MITRAC12 ENSG00000183978 Cytochrome c oxidase assembly factor 3 17 42795147-42798704 Predicted membrane proteins Evidence at protein level HPA031966 Approved Supported Mitochondria Cervical cancer:3.40e-4 (favourable), Renal cancer:6.62e-4 (favourable), Endometrial cancer:8.93e-4 (favourable) Expressed in all Expressed in all epididymis: 210.1 COA4 CHCHD8, CMC3, E2IG2 ENSG00000181924 Cytochrome c oxidase assembly factor 4 homolog 11 73872667-73876988 Predicted intracellular proteins Evidence at protein level HPA040126 Approved Approved Nucleus
Nucleoli fibrillar center
Mitochondria Renal cancer:2.14e-4 (unfavourable), Ovarian cancer:3.87e-4 (favourable) Expressed in all Expressed in all adrenal gland: 81.8 COA5 C2orf64, FLJ27524, MGC52110, Pet191 ENSG00000183513 Cytochrome c oxidase assembly factor 5 2 98599310-98608515 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA057768 Uncertain Supported Mitochondria Urothelial cancer:1.00e-5 (favourable), Lung cancer:2.65e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 42.5 COA6 C1orf31 ENSG00000168275 Cytochrome c oxidase assembly factor 6 1 234373456-234384049 Predicted intracellular proteins Evidence at protein level HPA028588 Approved Supported Mitochondria Renal cancer:1.12e-5 (unfavourable), Urothelial cancer:7.12e-4 (favourable) Expressed in all Expressed in all duodenum: 46.7 COA7 C1orf163, FLJ12439, RESA1, SELRC1 ENSG00000162377 Cytochrome c oxidase assembly factor 7 (putative) 1 52684451-52698366 Predicted intracellular proteins Evidence at protein level HPA028154, HPA029926 Approved Approved Nucleus
Mitochondria Liver cancer:7.01e-5 (unfavourable), Stomach cancer:4.35e-4 (favourable), Endometrial cancer:8.55e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 14.7 COASY CoASY, DPCK, NBP, PPAT ENSG00000068120 CoA synthase 17 42561467-42566277 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022875, HPA022912, HPA023273 Approved Approved Nucleoplasm
Cytosol Liver cancer:7.54e-5 (unfavourable), Endometrial cancer:2.15e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 58.9 COG1 KIAA1381, LDLB ENSG00000166685 Component of oligomeric golgi complex 1 17 73192632-73208507 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029224 Supported Liver cancer:2.91e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 50.9 COG2 LDLC ENSG00000135775 Component of oligomeric golgi complex 2 1 230642489-230693982 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA076994 Approved Golgi apparatus Colorectal cancer:9.76e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 75.7 COG3 SEC34 ENSG00000136152 Component of oligomeric golgi complex 3 13 45464898-45536630 Predicted secreted proteins Evidence at protein level HPA040353 Approved Ovarian cancer:9.53e-4 (unfavourable) Expressed in all Expressed in all prostate: 29.8 COG4 COD1, DKFZP586E1519 ENSG00000103051 Component of oligomeric golgi complex 4 16 70480568-70523565 Predicted intracellular proteins Evidence at protein level HPA040924, HPA042539 Approved Approved Golgi apparatus
Vesicles Liver cancer:1.64e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 47.6 COG5 GOLTC1, GTC90 ENSG00000164597 Component of oligomeric golgi complex 5 7 107201555-107564514 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020300, HPA041583 Uncertain Validated Nucleoplasm
Golgi apparatus Thyroid cancer:1.48e-4 (unfavourable), Liver cancer:3.77e-4 (unfavourable), Endometrial cancer:9.72e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 46.1 COG6 COD2, KIAA1134 ENSG00000133103 Component of oligomeric golgi complex 6 13 39655627-39791665 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040410, HPA040441 Uncertain Approved Nuclear speckles
Golgi apparatus Stomach cancer:2.81e-4 (favourable) Expressed in all Expressed in all testis: 31.6 COG7 ENSG00000168434 Component of oligomeric golgi complex 7 16 23388493-23453180 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040758, HPA064645 Uncertain Validated Golgi apparatus Renal cancer:3.14e-4 (favourable), Endometrial cancer:6.95e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.4 COG8 DOR1, FLJ22315 ENSG00000213380 Component of oligomeric golgi complex 8 16 69320140-69339667 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041406, HPA049429 Approved Supported Golgi apparatus Renal cancer:2.47e-7 (favourable), Pancreatic cancer:3.12e-5 (favourable) Expressed in all Expressed in all testis: 39.6 COL18A1 KNO, KNO1, KS ENSG00000182871 Collagen, type XVIII, alpha 1 21 45405137-45513720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB001961, HPA011025, HPA036104 Approved Approved Golgi apparatus Liver cancer:6.16e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 129.0 COL1A1 OI4 ENSG00000108821 Collagen, type I, alpha 1 17 50183289-50201632 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008405, HPA011795 Uncertain Approved Vesicles
Cytosol Renal cancer:7.19e-12 (unfavourable), Lung cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 1863.2 COL1A2 OI4 ENSG00000164692 Collagen, type I, alpha 2 7 94394561-94431232 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB032650, HPA059738 Approved Supported Endoplasmic reticulum Renal cancer:1.51e-9 (unfavourable) Expressed in all Expressed in all cervix, uterine: 2933.7 COL4A3BP CERT, GPBP, STARD11 ENSG00000113163 Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 5 75368486-75512138 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035645, HPA042608 Uncertain Validated Nucleoplasm
Golgi apparatus Renal cancer:1.24e-5 (favourable) Expressed in all Expressed in all thyroid gland: 70.3 COL6A2 ENSG00000142173 Collagen, type VI, alpha 2 21 46098097-46132849 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007029, HPA030920, HPA038799 Supported Approved Plasma membrane
Cytosol Renal cancer:8.72e-14 (unfavourable) Expressed in all Expressed in all placenta: 470.8 COLGALT1 FLJ22329, GLT25D1 ENSG00000130309 Collagen beta(1-O)galactosyltransferase 1 19 17555594-17583162 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047821 Approved Approved Vesicles Renal cancer:0.00e+0 (unfavourable), Liver cancer:1.65e-5 (unfavourable), Pancreatic cancer:1.92e-4 (unfavourable), Urothelial cancer:3.83e-4 (unfavourable) Expressed in all Expressed in all placenta: 57.6 COMMD1 C2orf5, MGC27155, MURR1 ENSG00000173163 Copper metabolism (Murr1) domain containing 1 2 61888724-62147247 Predicted intracellular proteins Evidence at protein level HPA034633, HPA049223 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 47.6 COMMD10 PTD002 ENSG00000145781 COMM domain containing 10 5 116084991-116412762 Predicted intracellular proteins Evidence at protein level HPA045441, HPA075641 Approved Uncertain Plasma membrane
Cytosol Stomach cancer:2.99e-4 (unfavourable), Thyroid cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 46.7 COMMD2 HSPC042 ENSG00000114744 COMM domain containing 2 3 149738470-149752499 Predicted intracellular proteins Evidence at protein level HPA044190 Uncertain Approved Nucleoplasm
Nuclear bodies Pancreatic cancer:3.69e-6 (unfavourable), Liver cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 23.4 COMMD3 BUP, C10orf8 ENSG00000148444 COMM domain containing 3 10 22315974-22320308 Predicted intracellular proteins Evidence at protein level HPA036584 Approved Liver cancer:5.46e-7 (unfavourable) Expressed in all Expressed in all breast: 52.7 COMMD4 FLJ20452 ENSG00000140365 COMM domain containing 4 15 75335891-75343224 Predicted intracellular proteins Evidence at protein level HPA066957 Uncertain Supported Nucleus
Plasma membrane Expressed in all Expressed in all testis: 76.3 COMMD5 FLJ13008, HCaRG, HT002 ENSG00000170619 COMM domain containing 5 8 144841042-144853736 Predicted intracellular proteins Evidence at protein level HPA046905 Supported Nucleoplasm
Cytosol Expressed in all Expressed in all lymph node: 18.5 COMMD6 Acrg ENSG00000188243 COMM domain containing 6 13 75525219-75549439 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all ovary: 287.6 COMMD7 C20orf92, dJ1085F17.3 ENSG00000149600 COMM domain containing 7 20 32702691-32743997 Predicted intracellular proteins Evidence at protein level HPA054119 Supported Vesicles Liver cancer:1.46e-4 (unfavourable), Urothelial cancer:3.53e-4 (favourable) Expressed in all Expressed in all thyroid gland: 80.0 COMMD8 FLJ20502 ENSG00000169019 COMM domain containing 8 4 47450796-47463719 Predicted intracellular proteins Evidence at protein level HPA035887 Approved Supported Nucleoplasm
Cytosol Renal cancer:2.71e-5 (favourable), Liver cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all kidney: 46.0 COMMD9 FLJ31106, HSPC166 ENSG00000110442 COMM domain containing 9 11 36269284-36289449 Predicted intracellular proteins Evidence at protein level HPA009142 Uncertain Approved Nucleus
Golgi apparatus
Cytosol Ovarian cancer:8.54e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 48.4 COMT ENSG00000093010 Catechol-O-methyltransferase 22 19941607-19969975 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001169, CAB011233 Supported Approved Endoplasmic reticulum
Vesicles Endometrial cancer:3.68e-4 (favourable), Prostate cancer:5.67e-4 (favourable), Renal cancer:9.76e-4 (unfavourable) Expressed in all Expressed in all placenta: 172.0 COPA HEP-COP ENSG00000122218 Coatomer protein complex, subunit alpha 1 160289273-160343400 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028024 Supported Approved Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:1.08e-4 (unfavourable), Cervical cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 116.6 COPB1 COPB ENSG00000129083 Coatomer protein complex, subunit beta 1 11 14443440-14500027 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012338, HPA043954, HPA064403 Supported Validated Golgi apparatus
Vesicles
Cytosol Liver cancer:5.63e-7 (unfavourable), Head and neck cancer:6.91e-4 (unfavourable), Pancreatic cancer:8.04e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 131.9 COPB2 beta'-COP, betaprime-COP ENSG00000184432 Coatomer protein complex, subunit beta 2 (beta prime) 3 139355600-139389732 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036867, HPA058180 Approved Approved Cytosol Liver cancer:2.41e-7 (unfavourable), Pancreatic cancer:1.45e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 171.6 COPE epsilon-COP ENSG00000105669 Coatomer protein complex, subunit epsilon 19 18899514-18919397 Predicted intracellular proteins Evidence at protein level CAB034345, HPA041605, HPA043576 Supported Validated Golgi apparatus Cervical cancer:2.41e-4 (favourable) Expressed in all Expressed in all testis: 122.8 COPG1 COPG ENSG00000181789 Coatomer protein complex, subunit gamma 1 3 129249606-129277773 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037866, HPA037867, HPA045712 Supported Supported Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:1.22e-6 (unfavourable) Expressed in all Expressed in all epididymis: 188.8 COPG2 2-COP ENSG00000158623 Coatomer protein complex, subunit gamma 2 7 130506238-130668748 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045712 Approved Expressed in all Expressed in all ovary: 48.0 COPRS C17orf79, COPR5, HSA272196, TTP1 ENSG00000172301 Coordinator of PRMT5, differentiation stimulator 17 31851864-31859337 Predicted intracellular proteins Evidence at protein level HPA052552 Approved Supported Nucleus
Plasma membrane
Cytosol Liver cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all testis: 266.6 COPS2 ALIEN, CSN2, TRIP15 ENSG00000166200 COP9 signalosome subunit 2 15 49106068-49155661 Predicted intracellular proteins Evidence at protein level HPA016867, HPA018271, HPA061071 Approved Validated Vesicles
Cytokinetic bridge Expressed in all Expressed in all thyroid gland: 103.1 COPS3 CSN3, SGN3 ENSG00000141030 COP9 signalosome subunit 3 17 17246820-17281293 Predicted intracellular proteins Evidence at protein level HPA021997, HPA050557 Approved Supported Nucleus
Cytosol Renal cancer:8.65e-5 (unfavourable), Prostate cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all testis: 162.3 COPS4 CSN4 ENSG00000138663 COP9 signalosome subunit 4 4 83034447-83075818 Predicted intracellular proteins Evidence at protein level HPA036894, HPA042828 Uncertain Supported Nuclear speckles Renal cancer:5.21e-6 (favourable), Colorectal cancer:4.14e-4 (favourable) Expressed in all Expressed in all testis: 78.6 COPS5 CSN5, JAB1, MOV-34, SGN5 ENSG00000121022 COP9 signalosome subunit 5 8 67043079-67083783 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004242, HPA004845, HPA051531 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 92.0 COPS6 CSN6, MOV34-34KD ENSG00000168090 COP9 signalosome subunit 6 7 100088954-100092200 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044315 Approved Supported Nucleoplasm Renal cancer:6.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 127.1 COPS7A CSN7A ENSG00000111652 COP9 signalosome subunit 7A 12 6723741-6731875 Predicted intracellular proteins Evidence at protein level HPA026915 Supported Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 90.4 COPS7B CSN7B ENSG00000144524 COP9 signalosome subunit 7B 2 231781671-231809254 Predicted intracellular proteins Evidence at protein level HPA034675, HPA034676 Uncertain Supported Nucleoplasm Renal cancer:1.50e-6 (unfavourable), Liver cancer:8.37e-6 (unfavourable) Expressed in all Expressed in all testis: 37.2 COPS8 COP9, CSN8, MGC1297, SGN8 ENSG00000198612 COP9 signalosome subunit 8 2 237085312-237100466 Predicted intracellular proteins Evidence at protein level HPA036485 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:4.70e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 116.4 COPZ1 CGI-120, COPZ ENSG00000111481 Coatomer protein complex, subunit zeta 1 12 54301202-54351849 Predicted intracellular proteins Evidence at protein level Liver cancer:6.40e-5 (unfavourable), Renal cancer:7.45e-5 (unfavourable), Breast cancer:7.84e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 191.8 COQ10A FLJ32452 ENSG00000135469 Coenzyme Q10A 12 56266858-56270966 Predicted intracellular proteins Evidence at protein level HPA068931 Approved Endoplasmic reticulum
Golgi apparatus
Cytosol Pancreatic cancer:2.06e-4 (favourable), Renal cancer:3.44e-4 (favourable), Colorectal cancer:5.46e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 97.2 COQ10B FLJ13448 ENSG00000115520 Coenzyme Q10B 2 197453423-197475308 Predicted intracellular proteins Evidence at protein level HPA046057 Approved Approved Cytosol Expressed in all Expressed in all adrenal gland: 49.9 COQ2 CL640, FLJ26072 ENSG00000173085 Coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 4 83261536-83284914 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA056599, HPA068727 Approved Approved Cytosol Expressed in all Expressed in all adrenal gland: 18.5 COQ3 bA9819.1 ENSG00000132423 Coenzyme Q3 methyltransferase 6 99369400-99394204 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031273, HPA031274 Supported Approved Nucleoplasm
Mitochondria Renal cancer:6.86e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 20.6 COQ4 CGI-92 ENSG00000167113 Coenzyme Q4 9 128322536-128334072 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021406, HPA042945 Supported Supported Mitochondria Endometrial cancer:4.93e-6 (favourable), Renal cancer:5.76e-6 (favourable), Cervical cancer:2.97e-5 (favourable) Expressed in all Expressed in all fallopian tube: 64.1 COQ5 MGC4767 ENSG00000110871 Coenzyme Q5, methyltransferase 12 120503274-120534434 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049487 Approved Approved Nucleoli
Mitochondria Expressed in all Expressed in all thyroid gland: 42.0 COQ6 CGI-10 ENSG00000119723 Coenzyme Q6 monooxygenase 14 73949926-73963670 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA051371 Uncertain Renal cancer:1.05e-6 (favourable) Expressed in all Expressed in all adrenal gland: 32.9 COQ7 CAT5, CLK-1 ENSG00000167186 Coenzyme Q7 homolog, ubiquinone (yeast) 16 19067599-19080095 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067252, HPA071922 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:8.23e-12 (favourable) Expressed in all Expressed in all parathyroid gland: 38.6 COQ9 C16orf49, DKFZP434K046 ENSG00000088682 Coenzyme Q9 16 57447425-57461275 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040918 Supported Approved Cytosol Renal cancer:9.03e-11 (favourable) Expressed in all Expressed in all parathyroid gland: 89.0 CORO1A coronin-1, HCORO1, p57 ENSG00000102879 Coronin, actin binding protein, 1A 16 30182827-30189076 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB046473, HPA051132 Supported Approved Cytosol Renal cancer:5.74e-7 (unfavourable), Head and neck cancer:4.42e-4 (favourable), Endometrial cancer:6.91e-4 (favourable) Expressed in all Expressed in all lymph node: 601.3 CORO1B coronin-2 ENSG00000172725 Coronin, actin binding protein, 1B 11 67435510-67443821 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017616, HPA040113, HPA070456 Supported Validated Plasma membrane
Cytosol Endometrial cancer:1.65e-4 (favourable) Expressed in all Expressed in all prostate: 77.2 CORO1C coronin-3, HCRNN4 ENSG00000110880 Coronin, actin binding protein, 1C 12 108645109-108731596 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041737 Approved Liver cancer:5.59e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 206.2 COTL1 CLP ENSG00000103187 Coactosin-like F-actin binding protein 1 16 84565594-84618077 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008918 Supported Renal cancer:5.51e-4 (unfavourable) Expressed in all Expressed in all lymph node: 427.6 COX10 ENSG00000006695 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 17 14069496-14208677 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA032005, HPA032006 Supported Supported Nucleoli
Mitochondria
Cytosol Renal cancer:4.32e-6 (favourable), Stomach cancer:8.73e-4 (favourable) Expressed in all Expressed in all testis: 43.0 COX11 COX11P ENSG00000166260 COX11 cytochrome c oxidase copper chaperone 17 54951902-54968785 Predicted membrane proteins Evidence at protein level HPA044020 Approved Colorectal cancer:4.30e-4 (favourable) Expressed in all Expressed in all duodenum: 62.9 COX14 C12orf62, MGC14288 ENSG00000178449 COX14 cytochrome c oxidase assembly factor 12 50111979-50120457 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044618, HPA062014 Approved Supported Mitochondria Melanoma:7.90e-4 (unfavourable) Expressed in all Expressed in all kidney: 86.0 COX15 CEMCOX2 ENSG00000014919 Cytochrome c oxidase assembly homolog 15 (yeast) 10 99711844-99732100 Disease related genes, Predicted membrane proteins Evidence at protein level HPA037727, HPA037728, HPA066096 Uncertain Supported Mitochondria Renal cancer:9.21e-6 (favourable) Expressed in all Expressed in all thyroid gland: 36.2 COX16 C14orf112, HSPC203 ENSG00000133983 COX16 cytochrome c oxidase assembly homolog 14 70325081-70359731 Predicted intracellular proteins Evidence at protein level HPA062659 Uncertain Supported Mitochondria Renal cancer:1.03e-12 (favourable) Expressed in all Expressed in all thyroid gland: 39.5 COX17 ENSG00000138495 COX17 cytochrome c oxidase copper chaperone 3 119654513-119677454 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA042226, HPA048158 Supported Supported Mitochondria Expressed in all Expressed in all adrenal gland: 115.3 COX19 MGC104475 ENSG00000240230 COX19 cytochrome c oxidase assembly factor 7 898778-975599 Predicted intracellular proteins Evidence at protein level HPA021226 Approved Validated Cytosol Expressed in all Expressed in all fallopian tube: 9.9 COX20 FAM36A, FLJ43269 ENSG00000203667 COX20 cytochrome c oxidase assembly factor 1 244835322-244845057 Predicted membrane proteins Evidence at protein level HPA043617, HPA045490 Approved Validated Mitochondria Ovarian cancer:3.13e-4 (favourable) Expressed in all Expressed in all adrenal gland: 46.7 COX4I1 COX4, COX4-1 ENSG00000131143 Cytochrome c oxidase subunit IV isoform 1 16 85798633-85807044 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA002485, CAB004080 Supported Supported Mitochondria Renal cancer:2.56e-8 (favourable) Expressed in all Expressed in all heart muscle: 1070.8 COX5A ENSG00000178741 Cytochrome c oxidase subunit Va 15 74919791-74938168 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA027526 Supported Renal cancer:6.06e-7 (favourable), Cervical cancer:2.15e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 548.5 COX5B ENSG00000135940 Cytochrome c oxidase subunit Vb 2 97646040-97648383 Predicted intracellular proteins, Transporters Evidence at protein level HPA034517 Supported Validated Mitochondria Urothelial cancer:2.73e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 447.8 COX6A1 COX6A ENSG00000111775 Cytochrome c oxidase subunit VIa polypeptide 1 12 120438090-120440742 Disease related genes, Predicted membrane proteins Evidence at protein level HPA062394 Approved Supported Mitochondria Renal cancer:6.50e-7 (favourable) Expressed in all Expressed in all duodenum: 589.3 COX6B1 COX6B, COXG ENSG00000126267 Cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 19 35648223-35658861 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004192 Supported Supported Mitochondria Renal cancer:5.42e-4 (favourable) Expressed in all Expressed in all heart muscle: 466.9 COX6C ENSG00000164919 Cytochrome c oxidase subunit VIc 8 99873200-99894062 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA014295, CAB016244 Supported Validated Mitochondria Expressed in all Expressed in all duodenum: 349.0 COX7A2 COX7AL, COXVIIa-L ENSG00000112695 Cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 6 75237675-75250323 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:3.43e-5 (favourable) Expressed in all Expressed in all testis: 635.8 COX7A2L COX7AR, COX7RP, EB1, SIG81 ENSG00000115944 Cytochrome c oxidase subunit VIIa polypeptide 2 like 2 42333546-42425088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059124, CAB073545 Validated Nucleoli
Mitochondria Liver cancer:4.13e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 255.6 COX7B ENSG00000131174 Cytochrome c oxidase subunit VIIb X 77899438-77907373 Disease related genes, Predicted membrane proteins Evidence at protein level HPA058041 Uncertain Renal cancer:6.80e-6 (favourable), Urothelial cancer:2.43e-4 (favourable) Expressed in all Expressed in all heart muscle: 62.6 COX7C ENSG00000127184 Cytochrome c oxidase subunit VIIc 5 86617904-86620962 Predicted membrane proteins, Transporters Evidence at protein level HPA046647 Approved Renal cancer:1.23e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 822.1 COX8A COX, COX8, COX8-2, COX8L, VIII, VIII-L ENSG00000176340 Cytochrome c oxidase subunit VIIIA (ubiquitous) 11 63974607-63976543 Predicted membrane proteins, Transporters Evidence at protein level HPA055942 Supported Renal cancer:2.51e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 512.5 CPD GP180 ENSG00000108582 Carboxypeptidase D 17 30378905-30469989 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052796, HPA055465 Approved Approved Nucleoplasm
Nuclear membrane
Nuclear speckles Expressed in all Expressed in all thyroid gland: 94.6 CPE ENSG00000109472 Carboxypeptidase E 4 165361194-165498320 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003819, CAB024907 Supported Approved Nucleoplasm
Vesicles
Centrosome Urothelial cancer:2.12e-4 (unfavourable), Renal cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1564.8 CPEB4 KIAA1673 ENSG00000113742 Cytoplasmic polyadenylation element binding protein 4 5 173888280-173961976 Predicted intracellular proteins Evidence at protein level HPA038394 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:4.99e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 117.4 CPNE1 CPN1 ENSG00000214078 Copine I 20 35626031-35664956 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047259, HPA072634 Approved Supported Nucleoplasm
Nuclear membrane Renal cancer:2.74e-10 (unfavourable) Expressed in all Expressed in all smooth muscle: 102.7 CPNE2 CPN2 ENSG00000140848 Copine II 16 57092537-57148367 Predicted intracellular proteins Evidence at protein level HPA041132 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all Expressed in all lung: 55.7 CPNE3 ENSG00000085719 Copine III 8 86484830-86561498 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029552 Uncertain Supported Nucleus
Nucleoli
Mitochondria
Cytosol Renal cancer:5.07e-4 (favourable) Expressed in all Expressed in all thyroid gland: 102.9 CPOX CPO, CPX, HCP ENSG00000080819 Coproporphyrinogen oxidase 3 98521132-98593723 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA015736, HPA054448 Validated Mitochondria Renal cancer:1.04e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 25.5 CPPED1 CSTP1, FLJ11151 ENSG00000103381 Calcineurin-like phosphoesterase domain containing 1 16 12659799-12804017 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040938, HPA041970 Uncertain Supported Plasma membrane
Cytosol Renal cancer:1.62e-9 (favourable), Breast cancer:9.72e-4 (unfavourable) Expressed in all Expressed in all spleen: 41.6 CPQ LDP, PGCP ENSG00000104324 Carboxypeptidase Q 8 96645227-97149654 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023235, HPA024490 Supported Approved Golgi apparatus
Vesicles Renal cancer:5.40e-5 (favourable), Glioma:9.75e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 380.7 CPSF1 ENSG00000071894 Cleavage and polyadenylation specific factor 1, 160kDa 8 144393229-144409349 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065167, HPA068906 Approved Nucleoplasm Renal cancer:6.54e-5 (unfavourable), Liver cancer:8.64e-4 (unfavourable) Expressed in all Expressed in all testis: 63.6 CPSF2 KIAA1367 ENSG00000165934 Cleavage and polyadenylation specific factor 2, 100kDa 14 92121937-92172145 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024238 Supported Approved Nucleoplasm
Vesicles Liver cancer:4.35e-7 (unfavourable) Expressed in all Expressed in all testis: 47.6 CPSF3 CPSF-73, CPSF73, YSH1 ENSG00000119203 Cleavage and polyadenylation specific factor 3, 73kDa 2 9423568-9473101 Predicted intracellular proteins Evidence at protein level HPA034657 Uncertain Liver cancer:3.64e-5 (unfavourable), Renal cancer:3.93e-5 (unfavourable) Expressed in all Expressed in all testis: 87.1 CPSF3L CPSF73L, FLJ20542, INT11, INTS11, RC-68 ENSG00000127054 Cleavage and polyadenylation specific factor 3-like 1 1311585-1324691 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028379, HPA029025 Approved Supported Nucleoplasm
Cytosol Liver cancer:7.44e-4 (unfavourable) Expressed in all Expressed in all testis: 76.5 CPSF4 CPSF30, NAR ENSG00000160917 Cleavage and polyadenylation specific factor 4, 30kDa 7 99438922-99457371 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049094, HPA066470 Uncertain Supported Nucleoplasm Renal cancer:1.68e-4 (unfavourable), Liver cancer:5.87e-4 (unfavourable) Expressed in all Expressed in all testis: 43.8 CPSF6 CFIM, CFIM68, HPBRII-4, HPBRII-7 ENSG00000111605 Cleavage and polyadenylation specific factor 6, 68kDa 12 69239537-69274358 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039973 Supported Validated Nucleoplasm
Nuclear speckles Liver cancer:1.91e-6 (unfavourable), Renal cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all lymph node: 56.0 CPSF7 FLJ12529 ENSG00000149532 Cleavage and polyadenylation specific factor 7, 59kDa 11 61402641-61430031 Predicted intracellular proteins Evidence at protein level HPA041094 Supported Supported Nucleoplasm
Cytosol Liver cancer:9.83e-4 (unfavourable) Expressed in all Expressed in all endometrium: 75.7 CPT1A CPT1, CPT1-L, L-CPT1 ENSG00000110090 Carnitine palmitoyltransferase 1A (liver) 11 68754620-68844410 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008835 Supported Supported Mitochondria Renal cancer:2.67e-7 (favourable), Breast cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all small intestine: 80.5 CPT1B CPT1-M, M-CPT1 ENSG00000205560 Carnitine palmitoyltransferase 1B (muscle) 22 50568861-50578465 Enzymes, Predicted membrane proteins Evidence at protein level HPA029583 Approved Mixed Expressed in all heart muscle: 110.6 CPT2 CPT1, CPTASE ENSG00000157184 Carnitine palmitoyltransferase 2 1 53196429-53214197 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028201, HPA028202, HPA028214 Supported Supported Nucleoplasm
Nucleoli
Mitochondria Renal cancer:1.46e-12 (favourable), Colorectal cancer:5.27e-4 (favourable) Expressed in all Expressed in all liver: 42.1 CPTP GLTPD1, MGC10334 ENSG00000224051 Ceramide-1-phosphate transfer protein 1 1324756-1328897 Predicted intracellular proteins Evidence at protein level HPA056832 Approved Approved Cytosol Renal cancer:1.75e-4 (favourable) Expressed in all Expressed in all testis: 47.0 CPVL ENSG00000106066 Carboxypeptidase, vitellogenic-like 7 28995231-29195451 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB003697, HPA045715, HPA056466 Supported Supported Endoplasmic reticulum Endometrial cancer:8.56e-6 (unfavourable), Urothelial cancer:4.99e-4 (unfavourable) Expressed in all Expressed in all spleen: 397.9 CRADD RAIDD ENSG00000169372 CASP2 and RIPK1 domain containing adaptor with death domain 12 93677375-93894840 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB005337 Uncertain Approved Nucleus
Cytosol Renal cancer:4.04e-9 (favourable), Cervical cancer:9.06e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 32.2 CRAT CAT1 ENSG00000095321 Carnitine O-acetyltransferase 9 129094810-129111189 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA019230, HPA020260, HPA022815 Supported Approved Nucleoplasm
Nuclear membrane Renal cancer:0.00e+0 (favourable), Endometrial cancer:2.36e-4 (favourable) Expressed in all Expressed in all testis: 116.2 CRBN MRT2, MRT2A ENSG00000113851 Cereblon 3 3148992-3179710 Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA045910 Approved Approved Nucleoli Expressed in all Expressed in all testis: 86.2 CRCP CGRP-RCP, RCP, RCP9 ENSG00000241258 CGRP receptor component 7 66114604-66154568 Predicted intracellular proteins Evidence at protein level HPA007216 Approved Approved Nuclear bodies Expressed in all Expressed in all parathyroid gland: 31.7 CREB1 ENSG00000118260 CAMP responsive element binding protein 1 2 207529737-207603431 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003803, HPA019150 Supported Validated Nucleoplasm Liver cancer:2.77e-5 (unfavourable) Expressed in all Expressed in all testis: 58.7 CREB3 Luman, LZIP, sLZIP ENSG00000107175 CAMP responsive element binding protein 3 9 35732320-35737007 Predicted membrane proteins, Transcription factors Evidence at protein level HPA030978 Supported Cytosol Renal cancer:3.77e-5 (favourable), Ovarian cancer:5.40e-4 (favourable), Liver cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all prostate: 54.5 CREB3L2 BBF2H7, TCAG_1951439 ENSG00000182158 CAMP responsive element binding protein 3-like 2 7 137874979-138002067 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA015068, HPA015534 Uncertain Supported Nucleoplasm
Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 109.9 CREB3L4 AIbZIP, ATCE1, CREB3, CREB4, hJAL ENSG00000143578 CAMP responsive element binding protein 3-like 4 1 153967534-153974363 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA038122 Supported Approved Nucleoplasm
Nuclear membrane
Mitochondria Endometrial cancer:7.21e-4 (favourable) Group enriched Expressed in all prostate: 171.5 CREBBP CBP, KAT3A, RSTS, RTS ENSG00000005339 CREB binding protein 16 3725054-3880726 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004212, HPA055861 Supported Validated Nucleoplasm
Nuclear bodies Renal cancer:6.24e-5 (favourable) Expressed in all Expressed in all testis: 60.4 CREBL2 ENSG00000111269 CAMP responsive element binding protein-like 2 12 12611827-12645108 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043738 Uncertain Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:2.26e-5 (favourable) Expressed in all Expressed in all adrenal gland: 174.3 CREBRF C5orf41, LRF ENSG00000164463 CREB3 regulatory factor 5 173056352-173139284 Predicted intracellular proteins Evidence at protein level HPA015329 Supported Nucleus Renal cancer:3.20e-7 (favourable), Urothelial cancer:9.30e-4 (favourable) Expressed in all Expressed in all bone marrow: 43.7 CREBZF ZF ENSG00000137504 CREB/ATF bZIP transcription factor 11 85659708-85682908 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021526, HPA063652 Uncertain Approved Nucleus
Mitochondria Expressed in all Expressed in all endometrium,parathyroid gland: 31.1 CREG1 CREG ENSG00000143162 Cellular repressor of E1A-stimulated genes 1 1 167529677-167553767 Predicted secreted proteins Evidence at protein level HPA056390 Approved Vesicles
Microtubules Expressed in all Expressed in all thyroid gland: 208.5 CRELD1 AVSD2 ENSG00000163703 Cysteine-rich with EGF-like domains 1 3 9933822-9945413 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026964 Uncertain Approved Nucleoli
Cytosol Glioma:6.05e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 65.6 CRELD2 MGC11256 ENSG00000184164 Cysteine-rich with EGF-like domains 2 22 49918167-49927540 Predicted secreted proteins Evidence at protein level HPA000603, CAB025604 Approved Renal cancer:1.34e-9 (unfavourable), Endometrial cancer:2.42e-7 (favourable) Expressed in all Expressed in all thyroid gland: 94.0 CREM hCREM-2 ENSG00000095794 CAMP responsive element modulator 10 35126791-35212958 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001818, CAB018352 Supported Supported Nucleus
Vesicles Renal cancer:1.23e-5 (unfavourable) Expressed in all Expressed in all testis: 337.8 CRIM1 S52 ENSG00000150938 Cysteine rich transmembrane BMP regulator 1 (chordin-like) 2 36355926-36551135 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000556 Approved Renal cancer:9.51e-4 (favourable) Expressed in all Expressed in all placenta: 238.1 CRIP1 CRIP ENSG00000213145 Cysteine-rich protein 1 (intestinal) 14 105486317-105488947 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042462 Approved Uncertain Nuclear speckles
Centrosome
Cytosol Mixed Expressed in all small intestine: 557.9 CRIPT HSPC139 ENSG00000119878 Cysteine-rich PDZ-binding protein 2 46616416-46625742 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046080, HPA056765 Approved Supported Nucleus
Nucleoli Liver cancer:1.19e-4 (unfavourable), Renal cancer:5.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.5 CRISPLD2 DKFZP434B044, LCRISP2 ENSG00000103196 Cysteine-rich secretory protein LCCL domain containing 2 16 84819984-84920768 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030055 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.97e-6 (unfavourable) Expressed in all Expressed in all placenta: 173.0 CRK ENSG00000167193 V-crk avian sarcoma virus CT10 oncogene homolog 17 1420689-1463162 Predicted intracellular proteins Evidence at protein level CAB010485, HPA068087 Approved Approved Plasma membrane Expressed in all Expressed in all thyroid gland: 60.9 CRKL ENSG00000099942 V-crk avian sarcoma virus CT10 oncogene homolog-like 22 20917426-20953749 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000532, HPA001100 Uncertain Validated Nucleoplasm
Cytosol Renal cancer:8.82e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 53.6 CRLS1 C20orf155, CLS1, dJ967N21.6, GCD10 ENSG00000088766 Cardiolipin synthase 1 20 6006090-6040053 Enzymes, Predicted membrane proteins Evidence at protein level Urothelial cancer:8.02e-4 (favourable) Expressed in all Expressed in all liver: 86.7 CRNKL1 CLF, Clf1, CRN, SYF3 ENSG00000101343 Crooked neck pre-mRNA splicing factor 1 20 20034368-20056046 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:8.06e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.8 CROT COT ENSG00000005469 Carnitine O-octanoyltransferase 7 87345681-87399795 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA019052, HPA019364, HPA019365 Supported Supported Vesicles Renal cancer:2.55e-6 (favourable), Urothelial cancer:4.02e-4 (favourable) Expressed in all Expressed in all thyroid gland: 68.1 CRTAP CASP, LEPREL3, P3H5 ENSG00000170275 Cartilage associated protein 3 33113979-33147773 Disease related genes, Predicted secreted proteins Evidence at protein level HPA043598, HPA044150 Approved Approved Intermediate filaments
Actin filaments
Cytosol Expressed in all Expressed in all cervix, uterine: 196.9 CRTC1 FLJ14027, KIAA0616, MECT1, TORC1 ENSG00000105662 CREB regulated transcription coactivator 1 19 18683677-18782333 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022035 Approved Supported Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Pancreatic cancer:1.80e-5 (favourable), Renal cancer:3.83e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 23.8 CRTC2 TORC2 ENSG00000160741 CREB regulated transcription coactivator 2 1 153947669-153958625 Predicted intracellular proteins Evidence at protein level HPA028454, HPA028465 Supported Validated Nucleoplasm Renal cancer:1.35e-7 (unfavourable), Urothelial cancer:6.12e-5 (favourable), Colorectal cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all spleen: 36.6 CRTC3 FLJ21868 ENSG00000140577 CREB regulated transcription coactivator 3 15 90529925-90645345 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043735, HPA063691 Uncertain Validated Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 50.5 CRY1 PHLL1 ENSG00000008405 Cryptochrome circadian clock 1 12 106991364-107093829 Predicted intracellular proteins Evidence at protein level CAB018762 Approved Supported Nucleus
Nuclear membrane
Microtubules Expressed in all Expressed in all testis: 61.9 CRY2 ENSG00000121671 Cryptochrome circadian clock 2 11 45847118-45883248 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037577 Supported Supported Nuclear speckles
Cytosol Renal cancer:6.44e-15 (favourable), Liver cancer:6.82e-5 (favourable), Colorectal cancer:1.67e-4 (unfavourable), Pancreatic cancer:4.39e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 56.4 CRYL1 GDH, lambda-CRY, MGC149525, MGC149526 ENSG00000165475 Crystallin, lambda 1 13 20403667-20525857 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040403 Supported Approved Nucleus
Nucleoli
Golgi apparatus
Plasma membrane Renal cancer:2.30e-9 (favourable), Endometrial cancer:1.76e-5 (favourable) Expressed in all Expressed in all kidney: 335.8 CRYZ ENSG00000116791 Crystallin, zeta (quinone reductase) 1 74705482-74733408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021921, HPA023290 Approved Supported Cytosol Expressed in all Expressed in all kidney: 342.7 CRYZL1 4P11, QOH-1 ENSG00000205758 Crystallin, zeta (quinone reductase)-like 1 21 33589341-33643926 Predicted intracellular proteins Evidence at protein level HPA019120, HPA029399, CAB034129 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 63.3 CS ENSG00000062485 Citrate synthase 12 56271699-56300392 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754 Supported Validated Mitochondria Renal cancer:1.17e-4 (favourable) Expressed in all Expressed in all heart muscle: 203.7 CSAD CSD, PCAP ENSG00000139631 Cysteine sulfinic acid decarboxylase 12 53157663-53180909 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039487 Approved Renal cancer:1.93e-6 (unfavourable), Urothelial cancer:6.81e-6 (favourable), Liver cancer:1.37e-4 (favourable), Pancreatic cancer:3.39e-4 (favourable), Head and neck cancer:6.33e-4 (favourable), Colorectal cancer:9.50e-4 (unfavourable) Expressed in all Expressed in all skin: 70.8 CSDE1 D1S155E, UNR ENSG00000009307 Cold shock domain containing E1, RNA-binding 1 114716913-114758676 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018846, HPA052221 Supported Validated Cytosol Expressed in all Expressed in all skeletal muscle: 490.4 CSE1L CAS, CSE1, XPO2 ENSG00000124207 CSE1 chromosome segregation 1-like (yeast) 20 49046246-49096960 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB002140, HPA038059, HPA038060 Supported Validated Nucleoplasm
Cytosol Liver cancer:2.42e-8 (unfavourable), Endometrial cancer:2.91e-5 (unfavourable), Renal cancer:1.89e-4 (unfavourable), Urothelial cancer:6.91e-4 (unfavourable) Expressed in all Expressed in all testis: 158.9 CSF1 M-CSF, MCSF, MGC31930 ENSG00000184371 Colony stimulating factor 1 (macrophage) 1 109910242-109930992 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA076624 Supported Plasma membrane Renal cancer:1.00e-11 (unfavourable), Liver cancer:4.25e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 66.1 CSGALNACT1 ChGn, CSGalNAcT-1, FLJ11264 ENSG00000147408 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 8 19404161-19758029 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA061336 Supported Actin filaments Expressed in all Expressed in all thyroid gland: 144.8 CSGALNACT2 GALNACT-2, GALNACT2, MGC40204, PRO0082 ENSG00000169826 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 10 43138486-43185308 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031540 Approved Approved Endoplasmic reticulum Renal cancer:3.53e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 87.4 CSK ENSG00000103653 C-src tyrosine kinase 15 74782057-74803198 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011203, HPA026488, HPA028425 Approved Approved Vesicles
Cytosol Cervical cancer:5.14e-5 (favourable), Stomach cancer:1.07e-4 (favourable), Renal cancer:1.74e-4 (unfavourable), Endometrial cancer:8.22e-4 (favourable) Expressed in all Expressed in all lymph node: 197.7 CSNK1A1 CK1, CK1a, CK1alpha, CKIa, CKIalpha ENSG00000113712 Casein kinase 1, alpha 1 5 149492197-149551552 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB016680, HPA051334 Uncertain Approved Cytosol Colorectal cancer:1.15e-4 (favourable), Pancreatic cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 230.2 CSNK1D CKID, CKIdelta, HCKID ENSG00000141551 Casein kinase 1, delta 17 82239023-82273731 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB015410 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:2.38e-6 (unfavourable), Pancreatic cancer:9.62e-5 (favourable), Endometrial cancer:7.04e-4 (unfavourable), Renal cancer:8.34e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 67.1 CSNK1E CKIE, CKIepsilon, HCKIE ENSG00000213923 Casein kinase 1, epsilon 22 38290691-38398522 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB009626, HPA026288 Approved Approved Nucleus
Cytosol Renal cancer:4.67e-6 (unfavourable), Liver cancer:8.20e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 173.6 CSNK1G2 CK1g2 ENSG00000133275 Casein kinase 1, gamma 2 19 1941149-1981338 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034868, HPA056572 Uncertain Approved Vesicles Expressed in all Expressed in all testis: 77.2 CSNK1G3 ENSG00000151292 Casein kinase 1, gamma 3 5 123512099-123617045 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027010 Approved Colorectal cancer:9.90e-5 (favourable) Expressed in all Expressed in all testis: 28.2 CSNK2A1 ENSG00000101266 Casein kinase 2, alpha 1 polypeptide 20 473591-543821 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB020680, HPA059206, CAB069395 Approved Supported Nucleoplasm Liver cancer:4.11e-6 (unfavourable) Expressed in all Expressed in all testis: 133.0 CSNK2A2 CSNK2A1 ENSG00000070770 Casein kinase 2, alpha prime polypeptide 16 58157907-58197920 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA077719 Approved Nucleoplasm
Vesicles
Cytosol Head and neck cancer:1.40e-5 (unfavourable), Liver cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all testis: 236.7 CSPP1 CSPP, FLJ22490, JBTS21 ENSG00000104218 Centrosome and spindle pole associated protein 1 8 67062426-67196263 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056174 Supported Microtubule organizing center Thyroid cancer:2.98e-4 (unfavourable) Expressed in all Expressed in all testis: 34.8 CSRNP1 AXUD1, DKFZp566F164, FAM130B, TAIP-3, URAX1 ENSG00000144655 Cysteine-serine-rich nuclear protein 1 3 39141855-39154562 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045207, HPA058463 Validated Nucleoplasm
Vesicles Renal cancer:1.07e-4 (favourable), Stomach cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 123.7 CSRNP2 C12ORF2, C12orf22, FAM130A1, PPP1R72, TAIP-12 ENSG00000110925 Cysteine-serine-rich nuclear protein 2 12 51061205-51083664 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018503, HPA019914 Approved Approved Nuclear speckles Liver cancer:1.08e-4 (unfavourable), Urothelial cancer:2.78e-4 (favourable), Renal cancer:6.51e-4 (unfavourable) Expressed in all Expressed in all testis: 49.1 CSRP1 CSRP, CYRP, D1S181E ENSG00000159176 Cysteine and glycine-rich protein 1 1 201483530-201509456 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045617 Uncertain Renal cancer:2.11e-4 (unfavourable), Head and neck cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 3274.8 CSRP2BP ATAC2, CRP2BP, dJ717M23.1, KAT14, PRO1194 ENSG00000149474 CSRP2 binding protein 20 18138118-18188387 Predicted intracellular proteins Evidence at protein level CAB034224, HPA068443 Uncertain Approved Vesicles Renal cancer:4.64e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.0 CST3 ENSG00000101439 Cystatin C 20 23626706-23638473 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000118, HPA013143 Supported Supported Golgi apparatus
Vesicles Endometrial cancer:1.83e-4 (favourable), Urothelial cancer:8.77e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1269.6 CSTF1 ENSG00000101138 Cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 20 56392371-56406369 Predicted intracellular proteins Evidence at protein level CAB019270, HPA047275, HPA065000 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 31.2 CSTF2T CstF-64T, DKFZp434C1013, KIAA0689 ENSG00000177613 Cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 10 51695487-51699591 Predicted intracellular proteins Evidence at protein level HPA039216, HPA062021 Approved Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 37.2 CSTF3 CstF-77 ENSG00000176102 Cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 11 33077188-33162371 Predicted intracellular proteins Evidence at protein level HPA039743, HPA040168 Supported Validated Nucleoplasm Liver cancer:8.20e-6 (unfavourable), Renal cancer:1.61e-5 (unfavourable), Colorectal cancer:1.63e-4 (favourable) Expressed in all Expressed in all epididymis: 76.2 CTAGE5 cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, MEA6, MGEA, MGEA11, MGEA6 ENSG00000150527 CTAGE family, member 5 14 39265284-39388513 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000387, HPA000922 Uncertain Renal cancer:2.81e-4 (favourable) Mixed Expressed in all thyroid gland: 77.3 CTB-50L17.10 ENSG00000167674 Hepatoma-derived growth factor-related protein 2 19 4472287-4502211 Predicted intracellular proteins Evidence at protein level HPA042559, HPA044208 Supported Supported Nucleoplasm Pancreatic cancer:6.57e-4 (favourable) Expressed in all Expressed in all testis: 62.3 CTBP1 BARS ENSG00000159692 C-terminal binding protein 1 4 1211448-1249953 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004217, HPA018987, HPA044971 Approved Validated Nucleoplasm Endometrial cancer:4.03e-4 (favourable), Urothelial cancer:8.94e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 142.1 CTBP2 ribeye ENSG00000175029 C-terminal binding protein 2 10 124984317-125161170 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023559, HPA023564, CAB031916, HPA044971 Approved Approved Cytosol Renal cancer:1.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 90.3 CTC1 AAF132, C17orf68, FLJ22170 ENSG00000178971 CTS telomere maintenance complex component 1 17 8224821-8248044 Disease related genes, Predicted intracellular proteins Evidence at protein level Pancreatic cancer:6.49e-5 (favourable) Expressed in all Expressed in all spleen: 31.5 CTCF ENSG00000102974 CCCTC-binding factor (zinc finger protein) 16 67562407-67639183 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004122, CAB062550, CAB068181, CAB068182 Supported Supported Nucleoplasm Renal cancer:4.06e-4 (favourable), Liver cancer:4.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 57.7 CTDNEP1 DULLARD, HSA011916, NET56 ENSG00000175826 CTD nuclear envelope phosphatase 1 17 7243591-7252491 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037439 Uncertain Pancreatic cancer:1.81e-4 (favourable), Endometrial cancer:6.45e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 190.2 CTDP1 FCP1 ENSG00000060069 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 18 79679801-79756623 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB032641, HPA040394 Supported Supported Nuclear speckles
Actin filaments Renal cancer:5.51e-5 (favourable), Endometrial cancer:6.43e-4 (favourable) Expressed in all Expressed in all testis: 19.6 CTDSP1 NLIIF, SCP1 ENSG00000144579 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 2 218398256-218405941 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062654 Supported Nucleoplasm Expressed in all Expressed in all placenta: 106.2 CTDSP2 OS4, PSR2, SCP2 ENSG00000175215 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 12 57819927-57846739 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052607 Uncertain Uncertain Nucleoplasm Expressed in all Expressed in all lung: 170.4 CTDSPL C3orf8, HYA22, PSR1, RBSP3, SCP3 ENSG00000144677 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 3 37861960-37984469 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048325 Approved Approved Nucleoplasm
Vesicles Renal cancer:6.22e-14 (favourable) Expressed in all Expressed in all skin: 65.8 CTDSPL2 FLJ10523, HSPC129 ENSG00000137770 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 15 44427234-44529038 Predicted intracellular proteins Evidence at protein level HPA040763, HPA062198 Approved Validated Nucleoplasm Expressed in all Expressed in all testis: 37.5 CTGF CCN2, IGFBP8 ENSG00000118523 Connective tissue growth factor 6 131948176-131951373 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB005123, HPA031074, HPA031075 Approved Validated Golgi apparatus
Vesicles Stomach cancer:5.04e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 841.0 CTH ENSG00000116761 Cystathionine gamma-lyase 1 70411218-70439851 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021591, HPA023300 Supported Liver cancer:8.69e-4 (favourable) Group enriched Expressed in all liver: 73.1 CTNNA1 CAP102 ENSG00000044115 Catenin (cadherin-associated protein), alpha 1, 102kDa 5 138610967-138935034 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB021089, HPA046119, HPA063535 Approved Validated Plasma membrane
Cell Junctions Renal cancer:7.34e-7 (favourable), Pancreatic cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 215.4 CTNNAL1 alpha-CATU, CLLP ENSG00000119326 Catenin (cadherin-associated protein), alpha-like 1 9 108942569-109013529 Predicted intracellular proteins Evidence at protein level Stomach cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 264.1 CTNNB1 armadillo, beta-catenin, CTNNB ENSG00000168036 Catenin (cadherin-associated protein), beta 1, 88kDa 3 41194837-41260096 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000108, CAB001950, HPA029159, HPA029160 Supported Validated Plasma membrane Colorectal cancer:7.54e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 285.2 CTNNBIP1 ICAT, MGC15093 ENSG00000178585 Catenin, beta interacting protein 1 1 9848276-9910336 Predicted intracellular proteins Evidence at protein level HPA042617 Approved Plasma membrane
Cell Junctions
Mitochondria Endometrial cancer:5.68e-6 (favourable) Expressed in all Expressed in all skin: 288.8 CTNNBL1 C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L ENSG00000132792 Catenin, beta like 1 20 37693955-37872129 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA004742, HPA027907 Approved Validated Nucleoplasm Expressed in all Expressed in all testis: 75.0 CTNND1 CTNND, KIAA0384, p120, p120cas, p120ctn ENSG00000198561 Catenin (cadherin-associated protein), delta 1 11 57753243-57819546 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003837, HPA015954, HPA015955 Supported Validated Plasma membrane Pancreatic cancer:3.02e-4 (unfavourable), Renal cancer:3.54e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 192.9 CTNS CTNS-LSB, PQLC4 ENSG00000040531 Cystinosin, lysosomal cystine transporter 17 3636468-3661542 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA046947 Supported Vesicles
Intermediate filaments Pancreatic cancer:6.39e-5 (favourable), Head and neck cancer:7.33e-4 (favourable) Expressed in all Expressed in all testis: 43.3 CTPS1 CTPS ENSG00000171793 CTP synthase 1 1 40979335-41012565 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017111, HPA051322 Approved Supported Actin filaments
Cytosol Expressed in all Expressed in all smooth muscle: 79.3 CTPS2 ENSG00000047230 CTP synthase 2 X 16588003-16712936 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017437 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:2.37e-5 (unfavourable), Urothelial cancer:4.56e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.6 CTR9 KIAA0155, p150TSP, SH2BP1, TSBP ENSG00000198730 CTR9 homolog, Paf1/RNA polymerase II complex component 11 10750987-10779743 Predicted intracellular proteins Evidence at protein level HPA061027, HPA068122 Supported Validated Nucleoplasm Renal cancer:3.65e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 59.0 CTSA GSL, PPGB ENSG00000064601 Cathepsin A 20 45890144-45898820 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB024930, HPA031068 Supported Validated Vesicles Liver cancer:1.95e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 244.6 CTSB ENSG00000164733 Cathepsin B 8 11842524-11869448 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000457, HPA018156 Uncertain Supported Nucleoli
Vesicles Thyroid cancer:5.76e-4 (favourable), Urothelial cancer:9.02e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 2885.5 CTSC DPP1, PALS, PLS ENSG00000109861 Cathepsin C 11 88293592-88337787 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025364, HPA066610, HPA068434 Supported Supported Vesicles Liver cancer:9.30e-5 (unfavourable), Renal cancer:4.80e-4 (favourable) Expressed in all Expressed in all lung: 390.6 CTSD CLN10, CPSD ENSG00000117984 Cathepsin D 11 1752752-1763992 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000109, HPA003001 Supported Renal cancer:4.93e-5 (favourable), Colorectal cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all lung: 1071.1 CTSF CATSF, CLN13 ENSG00000174080 Cathepsin F 11 66563463-66568841 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002141, HPA031431, HPA055610 Approved Approved Vesicles
Plasma membrane
Cytosol Renal cancer:8.92e-7 (favourable) Expressed in all Expressed in all ovary: 140.1 CTSH ACC-4, ACC-5, ACC4, ACC5, CPSB ENSG00000103811 Cathepsin H 15 78921058-78949574 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000458, HPA003524 Supported Supported Vesicles
Cytosol
Cytoplasmic bodies Endometrial cancer:6.90e-4 (favourable) Expressed in all Expressed in all lung: 570.4 CTSK CTSO, CTSO2, PKND, PYCD ENSG00000143387 Cathepsin K 1 150796208-150808323 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050346 Supported Vesicles Renal cancer:7.12e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 571.4 CTSL CTSL1, FLJ31037 ENSG00000135047 Cathepsin L 9 87725519-87731393 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000459 Supported Lung cancer:5.15e-5 (unfavourable), Renal cancer:4.34e-4 (favourable), Glioma:4.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 744.0 CTSO CTSO1 ENSG00000256043 Cathepsin O 4 155924118-155953917 Enzymes, Predicted secreted proteins Evidence at protein level HPA002041 Approved Expressed in all Expressed in all gallbladder: 32.5 CTSS ENSG00000163131 Cathepsin S 1 150730196-150765957 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000460, HPA002988 Supported Approved Vesicles Expressed in all Expressed in all spleen: 381.4 CTSZ CTSX ENSG00000101160 Cathepsin Z 20 58995185-59007247 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025114, HPA049876, HPA053504 Supported Supported Vesicles Renal cancer:5.72e-5 (unfavourable) Expressed in all Expressed in all lung: 477.4 CTTN EMS1 ENSG00000085733 Cortactin 11 70398404-70436584 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011235, HPA057242 Supported Supported Golgi apparatus
Vesicles
Plasma membrane
Cytosol Head and neck cancer:2.19e-6 (unfavourable), Liver cancer:4.45e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 109.3 CTU2 C16orf84, NCS2 ENSG00000174177 Cytosolic thiouridylase subunit 2 homolog (S. pombe) 16 88706463-88715386 Predicted intracellular proteins Evidence at protein level HPA041135, HPA041894 Uncertain Supported Mitochondria Liver cancer:5.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 10.3 CUEDC1 ENSG00000180891 CUE domain containing 1 17 57861243-57955323 Predicted intracellular proteins Evidence at protein level HPA023050, HPA024836 Approved Uncertain Centrosome
Mitochondria
Cytosol Liver cancer:2.65e-5 (unfavourable), Renal cancer:8.46e-4 (favourable) Expressed in all Expressed in all fallopian tube: 51.8 CUEDC2 C10orf66, MGC2491 ENSG00000107874 CUE domain containing 2 10 102423245-102432661 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036544, HPA041829 Uncertain Validated Nucleoplasm
Cytosol Liver cancer:2.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 90.2 CUL1 ENSG00000055130 Cullin 1 7 148697914-148801036 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002676, HPA064584 Supported Supported Nucleus
Nucleoli Expressed in all Expressed in all testis: 184.4 CUL2 ENSG00000108094 Cullin 2 10 35008551-35090642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002677, HPA024578 Approved Validated Nucleoplasm Liver cancer:8.24e-6 (unfavourable), Renal cancer:9.32e-5 (unfavourable) Expressed in all Expressed in all testis: 64.8 CUL3 ENSG00000036257 Cullin 3 2 224470150-224585397 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB002678 Supported Expressed in all Expressed in all testis: 400.5 CUL4A ENSG00000139842 Cullin 4A 13 113208193-113267108 Predicted intracellular proteins Evidence at protein level HPA058979 Approved Nucleoplasm Stomach cancer:2.84e-4 (favourable) Expressed in all Expressed in all testis: 89.9 CUL4B ENSG00000158290 Cullin 4B X 120524609-120575794 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003046, HPA011880, CAB017786, HPA058979 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 68.0 CUL5 VACM-1 ENSG00000166266 Cullin 5 11 108008733-108107776 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002185, CAB017787 Approved Approved Golgi apparatus
Cytosol Renal cancer:1.06e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 25.5 CUL7 dJ20C7.5, KIAA0076 ENSG00000044090 Cullin 7 6 43037617-43053945 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015449, HPA030095, HPA030096 Approved Renal cancer:2.19e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 26.2 CUTA ACHAP, C6orf82 ENSG00000112514 CutA divalent cation tolerance homolog (E. coli) 6 33416442-33418317 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016787, HPA064369 Uncertain Approved Plasma membrane
Focal adhesion sites Lung cancer:8.50e-4 (favourable) Expressed in all Expressed in all thyroid gland: 292.6 CUTC CGI-32 ENSG00000119929 CutC copper transporter 10 99702558-99756134 Predicted intracellular proteins, Transporters Evidence at protein level HPA038619 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.81e-7 (unfavourable) Expressed in all Expressed in all skeletal muscle: 131.6 CUX1 CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6 ENSG00000257923 Cut-like homeobox 1 7 101815904-102283957 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA003277, HPA003317 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:5.72e-7 (favourable), Glioma:9.90e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.3 CWC15 AD002, C11orf5, Cwf15, HSPC148 ENSG00000150316 CWC15 spliceosome-associated protein 11 94962622-94973612 Predicted intracellular proteins Evidence at protein level HPA039878 Supported Approved Nuclear speckles
Mitochondria Renal cancer:1.91e-5 (unfavourable), Thyroid cancer:7.17e-4 (favourable), Ovarian cancer:9.75e-4 (favourable) Expressed in all Expressed in all testis: 78.5 CWC22 EIF4GL, fSAPb, KIAA1604, NCM ENSG00000163510 CWC22 spliceosome-associated protein 2 179944876-180007113 Predicted intracellular proteins Evidence at protein level HPA036748 Approved Supported Nuclear speckles
Cytosol Renal cancer:7.76e-5 (unfavourable), Liver cancer:7.42e-4 (unfavourable) Expressed in all Expressed in all endometrium: 28.8 CWC27 NY-CO-10, SDCCAG-10, SDCCAG10 ENSG00000153015 CWC27 spliceosome-associated protein homolog 5 64768930-65018763 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020344, HPA024149, HPA065809 Approved Validated Nucleoplasm Liver cancer:5.27e-6 (unfavourable) Expressed in all Expressed in all testis: 31.0 CWF19L1 FLJ10998 ENSG00000095485 CWF19-like 1, cell cycle control (S. pombe) 10 100232298-100267680 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036889, HPA036890 Uncertain Approved Nucleoplasm
Golgi apparatus Liver cancer:6.90e-4 (unfavourable) Expressed in all Expressed in all testis: 26.0 CWF19L2 FLJ32343 ENSG00000152404 CWF19-like 2, cell cycle control (S. pombe) 11 107326345-107457844 Predicted intracellular proteins Evidence at protein level HPA038166 Uncertain Approved Nuclear speckles
Cytosol Expressed in all Expressed in all endometrium: 18.0 CXCL12 PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1 ENSG00000107562 Chemokine (C-X-C motif) ligand 12 10 44370165-44386493 Predicted secreted proteins Evidence at protein level CAB017564 Approved Expressed in all Expressed in all endometrium: 615.4 CXorf38 MGC39350 ENSG00000185753 Chromosome X open reading frame 38 X 40626921-40647554 Predicted intracellular proteins Evidence at protein level HPA050120 Approved Supported Cytosol Urothelial cancer:1.44e-8 (favourable), Pancreatic cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all spleen: 22.4 CXorf40A CXorf40, EOLA1 ENSG00000197620 Chromosome X open reading frame 40A X 149540355-149550510 Predicted intracellular proteins Evidence at protein level HPA060897 Approved Expressed in all Expressed in all adrenal gland: 70.8 CXorf40B ENSG00000197021 Chromosome X open reading frame 40B X 149929527-149938811 Predicted intracellular proteins Evidence at transcript level HPA060897 Approved Thyroid cancer:1.02e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 79.8 CXorf56 FLJ22965 ENSG00000018610 Chromosome X open reading frame 56 X 119538149-119565408 Predicted intracellular proteins Evidence at protein level HPA038245, HPA038617, HPA064831 Uncertain Approved Nucleus
Centrosome Breast cancer:3.45e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 24.0 CXXC1 CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1 ENSG00000154832 CXXC finger protein 1 18 50282343-50288304 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044511 Supported Validated Nucleus Liver cancer:4.18e-6 (unfavourable), Pancreatic cancer:2.60e-4 (favourable) Expressed in all Expressed in all lymph node: 28.6 CXXC5 HSPC195, RINF, WID ENSG00000171604 CXXC finger protein 5 5 139647299-139683882 Predicted intracellular proteins Evidence at protein level HPA036508, HPA058148 Approved Validated Nucleoplasm
Cytosol Endometrial cancer:4.10e-7 (unfavourable), Colorectal cancer:2.40e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 99.5 CYB561 CYB561A1, FRRS2 ENSG00000008283 Cytochrome b561 17 63432304-63446378 Predicted membrane proteins, Transporters Evidence at protein level HPA014753 Approved Endometrial cancer:2.95e-5 (favourable), Breast cancer:8.89e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 164.3 CYB561A3 CYBASC3 ENSG00000162144 Cytochrome b561 family, member A3 11 61348745-61362299 Predicted membrane proteins Evidence at protein level HPA052548 Uncertain Expressed in all Expressed in all adrenal gland: 188.0 CYB561D2 101F6, TSP10 ENSG00000114395 Cytochrome b561 family, member D2 3 50350695-50358460 Predicted membrane proteins Evidence at protein level HPA042817 Uncertain Renal cancer:6.16e-5 (favourable), Pancreatic cancer:1.86e-4 (favourable) Expressed in all Expressed in all epididymis: 28.3 CYB5A CYB5 ENSG00000166347 Cytochrome b5 type A (microsomal) 18 74250847-74292016 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB006333, HPA047548, HPA058547 Supported Approved Vesicles
Cytosol Liver cancer:4.15e-4 (favourable), Colorectal cancer:5.23e-4 (favourable) Expressed in all Expressed in all liver: 1254.1 CYB5B CYB5-M ENSG00000103018 Cytochrome b5 type B (outer mitochondrial membrane) 16 69424525-69466266 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007893 Approved Approved Endoplasmic reticulum
Microtubule organizing center
Cytosol Renal cancer:6.38e-5 (favourable), Head and neck cancer:2.51e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 399.7 CYB5D1 FLJ32499 ENSG00000182224 Cytochrome b5 domain containing 1 17 7857746-7862282 Predicted intracellular proteins Evidence at protein level HPA021632 Uncertain Approved Nucleoli
Golgi apparatus Mixed Expressed in all fallopian tube: 42.0 CYB5D2 MGC32124 ENSG00000167740 Cytochrome b5 domain containing 2 17 4143168-4187310 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042299 Approved Approved Nuclear membrane
Nucleoli
Centrosome Renal cancer:2.03e-10 (favourable), Liver cancer:4.98e-6 (favourable), Pancreatic cancer:7.76e-5 (favourable), Endometrial cancer:6.19e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.5 CYB5R1 humb5R2, NQO3A2 ENSG00000159348 Cytochrome b5 reductase 1 1 202961869-202967280 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010641, HPA014147 Supported Uncertain Nucleoli
Mitochondria
Cytosol Endometrial cancer:1.14e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 183.8 CYB5R3 DIA1 ENSG00000100243 Cytochrome b5 reductase 3 22 42617840-42649568 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001566 Approved Validated Endoplasmic reticulum Liver cancer:2.13e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 336.2 CYB5R4 b5+b5R, dJ676J13.1, NCB5OR ENSG00000065615 Cytochrome b5 reductase 4 6 83859643-83967424 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018992 Approved Expressed in all Expressed in all testis: 22.5 CYBA p22-PHOX ENSG00000051523 Cytochrome b-245, alpha polypeptide 16 88643283-88651152 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB009492 Supported Endometrial cancer:4.75e-5 (favourable), Renal cancer:1.83e-4 (unfavourable), Breast cancer:8.19e-4 (favourable) Expressed in all Expressed in all spleen: 476.3 CYBRD1 CYB561A2, DCYTB, FLJ23462, FRRS3 ENSG00000071967 Cytochrome b reductase 1 2 171522247-171558133 Predicted membrane proteins Evidence at protein level HPA014757, HPA056736 Approved Approved Golgi apparatus
Cytosol Expressed in all Expressed in all thyroid gland: 379.4 CYC1 UQCR4 ENSG00000179091 Cytochrome c-1 8 144095027-144097525 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA001247 Supported Supported Mitochondria Renal cancer:5.89e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 242.3 CYCS CYC, HCS ENSG00000172115 Cytochrome c, somatic 7 25120091-25125361 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004222, CAB005126, CAB018597 Supported Validated Mitochondria Renal cancer:1.30e-5 (favourable), Head and neck cancer:2.81e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 329.8 CYFIP1 KIAA0068, P140SRA-1, SHYC ENSG00000273749 Cytoplasmic FMR1 interacting protein 1 15 22867052-22981063 Predicted intracellular proteins Evidence at protein level HPA068106 Approved Renal cancer:4.47e-5 (favourable), Lung cancer:7.39e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 110.1 CYFIP2 PIR121 ENSG00000055163 Cytoplasmic FMR1 interacting protein 2 5 157266079-157395595 Predicted intracellular proteins Evidence at protein level CAB055519, HPA068106, HPA071459 Uncertain Approved Endoplasmic reticulum
Plasma membrane
Cytosol Renal cancer:3.21e-12 (favourable), Endometrial cancer:2.42e-6 (unfavourable), Pancreatic cancer:1.18e-4 (favourable) Expressed in all Expressed in all kidney: 165.0 CYGB HGB, STAP ENSG00000161544 Cytoglobin 17 76527356-76551175 Predicted intracellular proteins Evidence at protein level HPA017757, HPA061642 Approved Validated Nuclear speckles Endometrial cancer:2.55e-5 (favourable), Glioma:1.63e-4 (unfavourable), Renal cancer:2.13e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 46.6 CYHR1 CHRP, KIAA0496, MGC13010 ENSG00000187954 Cysteine/histidine-rich 1 8 144449582-144465677 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA053653, HPA059543 Approved Validated Nucleoplasm Colorectal cancer:1.05e-4 (unfavourable), Liver cancer:3.90e-4 (unfavourable) Expressed in all Expressed in all testis: 51.5 CYLD CYLD1, KIAA0849, USPL2 ENSG00000083799 Cylindromatosis (turban tumor syndrome) 16 50742050-50801935 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011713, HPA050095 Approved Supported Nucleoplasm
Microtubule organizing center Expressed in all Expressed in all testis: 70.2 CYP51A1 CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1 ENSG00000001630 Cytochrome P450, family 51, subfamily A, polypeptide 1 7 92112151-92142952 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041325, HPA043508 Approved Validated Endoplasmic reticulum Cervical cancer:6.12e-4 (unfavourable) Expressed in all Expressed in all testis: 175.2 CYSTM1 C5orf32, ORF1-FL49 ENSG00000120306 Cysteine-rich transmembrane module containing 1 5 140174642-140282052 Predicted intracellular proteins Evidence at protein level HPA050930 Supported Renal cancer:9.69e-5 (favourable), Endometrial cancer:1.31e-4 (favourable), Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all stomach: 482.5 CYTH1 B2-1, cytohesin-1, D17S811E, PSCD1 ENSG00000108669 Cytohesin 1 17 78674048-78782297 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047498 Uncertain Nucleus
Nucleoli Head and neck cancer:6.48e-4 (favourable) Expressed in all Expressed in all lymph node: 93.7 CYTH3 ARNO3, cytohesin-3, GRP1, PSCD3 ENSG00000008256 Cytohesin 3 7 6161776-6272644 Predicted intracellular proteins Evidence at protein level HPA013979 Uncertain Supported Nucleoplasm
Cytosol Urothelial cancer:2.63e-5 (unfavourable) Expressed in all Expressed in all placenta: 45.2 CYYR1 C21orf95 ENSG00000166265 Cysteine/tyrosine-rich 1 21 26466209-26573284 Predicted membrane proteins Evidence at transcript level CAB034921, HPA067685 Uncertain Approved Nucleoplasm Expressed in all Expressed in all adrenal gland: 60.4 D2HGDH D2HGD, FLJ42195, MGC25181 ENSG00000180902 D-2-hydroxyglutarate dehydrogenase 2 241734579-241768816 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA056216 Uncertain Head and neck cancer:9.11e-4 (favourable) Expressed in all Expressed in all skin: 46.4 DAAM1 KIAA0666 ENSG00000100592 Dishevelled associated activator of morphogenesis 1 14 59188646-59371405 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026605, HPA064789 Uncertain Approved Plasma membrane
Cytosol Renal cancer:3.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.1 DAAM2 KIAA0381 ENSG00000146122 Dishevelled associated activator of morphogenesis 2 6 39792298-39904877 Predicted intracellular proteins Evidence at protein level HPA051300, HPA054630 Approved Approved Nucleus
Cytosol Renal cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 111.1 DAB2 DOC-2 ENSG00000153071 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 5 39371675-39462300 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009314, HPA028888 Supported Supported Nucleoli
Vesicles
Plasma membrane Liver cancer:7.38e-6 (unfavourable), Stomach cancer:9.67e-4 (unfavourable) Expressed in all Expressed in all placenta: 319.5 DAD1 OST2 ENSG00000129562 Defender against cell death 1 14 22564905-22589269 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level HPA028882 Uncertain Approved Cytosol Liver cancer:7.73e-4 (unfavourable) Expressed in all Expressed in all epididymis: 507.2 DAG1 156DAG, A3a, AGRNR, DAG ENSG00000173402 Dystroglycan 1 (dystrophin-associated glycoprotein 1) 3 49468703-49535618 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB001960, CAB016353 Supported Approved Vesicles Renal cancer:2.59e-4 (favourable) Expressed in all Expressed in all placenta: 108.6 DAGLB DAGLBETA, KCCR13L ENSG00000164535 Diacylglycerol lipase, beta 7 6409126-6484190 Predicted membrane proteins Evidence at protein level HPA069377 Supported Plasma membrane Ovarian cancer:7.18e-5 (unfavourable), Renal cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 20.6 DALRD3 FLJ10496 ENSG00000178149 DALR anticodon binding domain containing 3 3 49015488-49022293 Predicted intracellular proteins Evidence at protein level HPA036862 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.79e-5 (favourable), Endometrial cancer:9.03e-4 (favourable) Expressed in all Expressed in all fallopian tube: 58.8 DAP ENSG00000112977 Death-associated protein 5 10679230-10761272 Predicted intracellular proteins Evidence at protein level HPA029456 Uncertain Approved Nucleoplasm
Vesicles
Mitochondria Liver cancer:2.15e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 153.7 DAP3 bMRP-10, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29 ENSG00000132676 Death associated protein 3 1 155687960-155739010 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023687 Approved Supported Nucleoplasm
Mitochondria Renal cancer:4.14e-6 (unfavourable), Liver cancer:1.20e-4 (unfavourable) Expressed in all Expressed in all prostate: 84.1 DAPK3 ZIP, ZIPK ENSG00000167657 Death-associated protein kinase 3 19 3958453-3971123 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028569, HPA064809 Approved Approved Nucleus Endometrial cancer:2.01e-5 (favourable), Renal cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all endometrium: 76.1 DARS ENSG00000115866 Aspartyl-tRNA synthetase 2 135906677-135986100 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020451, HPA029804, HPA029805 Supported Validated Cytosol Liver cancer:2.39e-6 (unfavourable), Renal cancer:1.24e-5 (unfavourable), Pancreatic cancer:6.54e-4 (unfavourable), Melanoma:7.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 90.6 DARS2 FLJ10514 ENSG00000117593 Aspartyl-tRNA synthetase 2, mitochondrial 1 173824503-173858546 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026506, HPA026528 Supported Supported Nucleus
Mitochondria Renal cancer:1.74e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.9 DAZAP1 MGC19907 ENSG00000071626 DAZ associated protein 1 19 1407569-1435687 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004201, HPA004631 Supported Validated Nucleoplasm
Cytosol Liver cancer:5.86e-4 (unfavourable) Expressed in all Expressed in all testis: 103.0 DAZAP2 KIAA0058 ENSG00000183283 DAZ associated protein 2 12 51238292-51271362 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045940 Supported Nuclear speckles Renal cancer:3.94e-9 (favourable) Expressed in all Expressed in all bone marrow: 337.2 DBI ACBD1, ACBP ENSG00000155368 Diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 2 119366921-119372560 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051428 Approved Renal cancer:3.73e-5 (unfavourable), Cervical cancer:5.77e-5 (favourable) Expressed in all Expressed in all breast: 898.4 DBN1 D0S117E ENSG00000113758 Drebrin 1 5 177456608-177474401 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051452, HPA056940 Supported Supported Plasma membrane
Actin filaments Renal cancer:8.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 83.2 DBNDD2 C20orf35, HSMNP1 ENSG00000244274 Dysbindin (dystrobrevin binding protein 1) domain containing 2 20 45406057-45410610 Predicted intracellular proteins Evidence at protein level HPA043991 Supported Approved Nucleoplasm
Cytosol Mixed Expressed in all cerebral cortex: 461.5 DBNL HIP-55, SH3P7 ENSG00000136279 Drebrin-like 7 44044640-44069456 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020265, HPA027735 Supported Supported Nucleoplasm
Cytosol Glioma:3.20e-5 (unfavourable) Expressed in all Expressed in all esophagus: 142.5 DBP DABP ENSG00000105516 D site of albumin promoter (albumin D-box) binding protein 19 48630030-48637438 Predicted intracellular proteins, Transcription factors Evidence at protein level Lung cancer:1.16e-5 (favourable), Renal cancer:2.41e-5 (favourable), Head and neck cancer:5.49e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.3 DBR1 ENSG00000138231 Debranching RNA lariats 1 3 138161012-138174949 Predicted intracellular proteins Evidence at protein level HPA035365 Supported Supported Nucleoplasm Liver cancer:1.36e-4 (unfavourable), Renal cancer:1.36e-4 (favourable) Expressed in all Expressed in all thyroid gland: 13.8 DBT ENSG00000137992 Dihydrolipoamide branched chain transacylase E2 1 100186919-100249834 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026481, HPA026485, HPA026533 Supported Supported Mitochondria Renal cancer:8.79e-12 (favourable) Expressed in all Expressed in all kidney: 19.6 DCAF10 FLJ23201, MGC10765, WDR32 ENSG00000122741 DDB1 and CUL4 associated factor 10 9 37800502-37867666 Predicted intracellular proteins Evidence at protein level HPA024160 Uncertain Approved Nucleoli fibrillar center Renal cancer:1.02e-6 (favourable) Expressed in all Expressed in all testis: 35.7 DCAF11 GL014, PRO2389, WDR23 ENSG00000100897 DDB1 and CUL4 associated factor 11 14 24114195-24125242 Predicted intracellular proteins Evidence at protein level HPA003583, HPA031157 Approved Validated Nucleoplasm Renal cancer:3.50e-13 (favourable) Expressed in all Expressed in all parathyroid gland: 73.0 DCAF12 CT102, DKFZP434O125, KIAA1892, MGC1058, TCC52, WDR40A ENSG00000198876 DDB1 and CUL4 associated factor 12 9 34086387-34127399 Predicted intracellular proteins Evidence at protein level HPA062279 Approved Ovarian cancer:2.81e-5 (favourable) Expressed in all Expressed in all testis: 112.9 DCAF13 DKFZP564O0463, Gm83, HSPC064, WDSOF1 ENSG00000164934 DDB1 and CUL4 associated factor 13 8 103414714-103443453 Predicted intracellular proteins Evidence at protein level HPA044504 Uncertain Supported Nucleus
Nucleoli
Cell Junctions
Centrosome
Cytosol Liver cancer:8.05e-6 (unfavourable), Renal cancer:2.85e-4 (unfavourable), Breast cancer:4.06e-4 (unfavourable) Expressed in all Expressed in all testis: 58.5 DCAF15 C19orf72, MGC99481 ENSG00000132017 DDB1 and CUL4 associated factor 15 19 13952492-13961449 Predicted intracellular proteins Evidence at protein level HPA068351 Approved Vesicles
Mitochondria Renal cancer:1.34e-5 (unfavourable), Pancreatic cancer:7.97e-4 (favourable) Expressed in all Expressed in all testis: 59.9 DCAF16 C4orf30, FLJ20280 ENSG00000163257 DDB1 and CUL4 associated factor 16 4 17800655-17810758 Predicted intracellular proteins Evidence at protein level HPA042487 Uncertain Approved Plasma membrane
Cytosol Lung cancer:5.78e-4 (favourable), Liver cancer:6.40e-4 (unfavourable), Urothelial cancer:7.67e-4 (favourable) Expressed in all Expressed in all endometrium: 22.9 DCAF17 C2orf37, FLJ13096 ENSG00000115827 DDB1 and CUL4 associated factor 17 2 171434217-171485052 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053339, HPA055040 Uncertain Supported Nucleoplasm Thyroid cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.0 DCAF4 DKFZp434K114, WDR21, WDR21A ENSG00000119599 DDB1 and CUL4 associated factor 4 14 72926332-72959703 Predicted intracellular proteins Evidence at protein level HPA047276 Approved Approved Nucleoplasm Renal cancer:4.90e-4 (favourable), Liver cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.8 DCAF5 BCRG2, BCRP2, D14S1461E, KIAA1824, WDR22 ENSG00000139990 DDB1 and CUL4 associated factor 5 14 69050881-69153150 Predicted intracellular proteins Evidence at protein level HPA041575, HPA048098 Uncertain Approved Mitochondria Expressed in all Expressed in all testis: 111.2 DCAF6 IQWD1, PC326 ENSG00000143164 DDB1 and CUL4 associated factor 6 1 167935783-168075843 Predicted intracellular proteins Evidence at protein level HPA054305 Supported Nucleus
Focal adhesion sites Expressed in all Expressed in all skeletal muscle: 223.5 DCAF7 HAN11, SWAN-1, WDR68 ENSG00000136485 DDB1 and CUL4 associated factor 7 17 63550461-63594266 Predicted intracellular proteins Evidence at protein level HPA022948, HPA022962 Approved Supported Nucleoplasm
Cytosol Liver cancer:2.42e-4 (unfavourable), Renal cancer:3.49e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 60.3 DCAF8 FLJ35857, H326, WDR42A ENSG00000132716 DDB1 and CUL4 associated factor 8 1 160215715-160262531 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027218, HPA027381 Supported Approved Nucleoplasm
Cytosol Renal cancer:3.74e-5 (unfavourable), Pancreatic cancer:4.71e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 153.1 DCAKD FLJ22955 ENSG00000172992 Dephospho-CoA kinase domain containing 17 45023340-45061109 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060997 Approved Nucleus Endometrial cancer:7.16e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 47.2 DCK ENSG00000156136 Deoxycytidine kinase 4 70992538-71030914 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA059609, HPA062773 Approved Supported Nucleus Liver cancer:6.90e-7 (unfavourable) Expressed in all Expressed in all lymph node: 95.0 DCN DSPG2, SLRR1B ENSG00000011465 Decorin 12 91140484-91183123 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003315, CAB017118, HPA064736, CAB068930 Supported Renal cancer:1.46e-5 (unfavourable) Expressed in all Expressed in all ovary: 3801.6 DCP1A HSA275986, SMAD4IP1, SMIF ENSG00000272886 Decapping mRNA 1A 3 53283428-53347610 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA013202 Approved Supported Cytoplasmic bodies Liver cancer:3.25e-5 (unfavourable), Colorectal cancer:9.01e-4 (favourable) Expressed in all Expressed in all endometrium: 19.0 DCP1B FLJ31638 ENSG00000151065 Decapping mRNA 1B 12 1946054-2004535 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039709, HPA058778 Approved Supported Vesicles
Cytosol Expressed in all Expressed in all testis: 36.6 DCPS HINT-5, HSL1, HSPC015 ENSG00000110063 Decapping enzyme, scavenger 11 126303752-126345749 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039632, HPA058597 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all lymph node: 24.9 DCTD ENSG00000129187 DCMP deaminase 4 182890060-182917936 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035894 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.81e-4 (favourable) Expressed in all Expressed in all thyroid gland: 166.5 DCTN1 ENSG00000204843 Dynactin 1 2 74361154-74392087 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009108, HPA034635 Approved Supported Actin filaments
Centrosome
Cytosol Renal cancer:2.34e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 210.5 DCTN2 DCTN-50, RBP50 ENSG00000175203 Dynactin 2 (p50) 12 57530102-57547331 Predicted intracellular proteins Evidence at protein level HPA039715, HPA040040 Approved Validated Centrosome Liver cancer:1.38e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 163.5 DCTN3 DCTN-22 ENSG00000137100 Dynactin 3 (p22) 9 34613545-34620523 Predicted intracellular proteins Evidence at protein level HPA044905 Approved Uncertain Nucleoli
Cytosol Renal cancer:5.76e-11 (favourable), Ovarian cancer:2.10e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 130.1 DCTN4 ENSG00000132912 Dynactin 4 (p62) 5 150708440-150759109 Predicted intracellular proteins Evidence at protein level CAB017532, HPA038026 Uncertain Approved Nucleus
Centrosome Expressed in all Expressed in all cerebral cortex: 67.5 DCTN5 MGC3248, p25 ENSG00000166847 Dynactin 5 (p25) 16 23641392-23677455 Predicted intracellular proteins Evidence at protein level HPA042003, HPA063710 Approved Supported Nucleoplasm
Nuclear membrane Liver cancer:4.02e-4 (unfavourable), Renal cancer:4.48e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 38.2 DCTN6 WS-3 ENSG00000104671 Dynactin 6 8 30156297-30183640 Predicted intracellular proteins Evidence at protein level HPA024049, HPA024558 Approved Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:5.42e-4 (favourable), Liver cancer:5.51e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 94.2 DCTPP1 CDA03, MGC5627, RS21C6, XTP3TPA ENSG00000179958 DCTP pyrophosphatase 1 16 30423619-30430075 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002832 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:9.71e-9 (favourable), Breast cancer:1.64e-5 (unfavourable), Liver cancer:6.28e-4 (unfavourable) Expressed in all Expressed in all rectum: 65.1 DCUN1D2 C13orf17, FLJ10704, FLJ20092 ENSG00000150401 DCN1, defective in cullin neddylation 1, domain containing 2 13 113455819-113490952 Predicted intracellular proteins Evidence at protein level HPA039349 Uncertain Approved Plasma membrane
Cytosol Pancreatic cancer:5.65e-5 (favourable) Expressed in all Expressed in all heart muscle: 65.3 DCUN1D4 KIAA0276 ENSG00000109184 DCN1, defective in cullin neddylation 1, domain containing 4 4 51843000-51916837 Predicted intracellular proteins Evidence at protein level HPA036483, HPA036484 Uncertain Approved Nucleus
Vesicles Expressed in all Expressed in all testis: 28.7 DCUN1D5 FLJ32431, MGC2714 ENSG00000137692 DCN1, defective in cullin neddylation 1, domain containing 5 11 103062076-103092215 Predicted intracellular proteins Evidence at protein level HPA050863 Approved Approved Nucleus
Nucleoli Liver cancer:2.01e-7 (unfavourable), Ovarian cancer:9.52e-5 (favourable), Prostate cancer:4.12e-4 (unfavourable), Head and neck cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all testis: 34.4 DDA1 C19orf58, MGC2594, PCIA1 ENSG00000130311 DET1 and DDB1 associated 1 19 17309518-17323301 Predicted intracellular proteins Evidence at protein level HPA042134, HPA055272 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all cerebral cortex: 11.6 DDB1 ENSG00000167986 Damage-specific DNA binding protein 1, 127kDa 11 61299451-61342596 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032821, HPA045174, HPA068456 Approved Validated Nucleoplasm Renal cancer:1.51e-8 (favourable), Colorectal cancer:7.09e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 480.7 DDB2 DDBB, FLJ34321, UV-DDB2, XPE ENSG00000134574 Damage-specific DNA binding protein 2, 48kDa 11 47214465-47239240 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB025912, HPA058406 Supported Supported Nucleoplasm
Cell Junctions Endometrial cancer:1.20e-4 (favourable), Cervical cancer:1.58e-4 (favourable), Breast cancer:7.29e-4 (favourable) Expressed in all Expressed in all skin: 53.8 DDHD2 KIAA0725, SAMWD1, SPG54 ENSG00000085788 DDHD domain containing 2 8 38225218-38275558 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015202, HPA023143, HPA023147 Supported Supported Microtubule organizing center
Cytosol Head and neck cancer:7.72e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 70.1 DDI2 MGC14844 ENSG00000197312 DNA-damage inducible 1 homolog 2 1 15617500-15669044 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043119, HPA043225 Approved Validated Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 19.3 DDIT3 CHOP, CHOP10, GADD153 ENSG00000175197 DNA-damage-inducible transcript 3 12 57516588-57520517 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058416, HPA068416 Approved Approved Nucleoplasm Liver cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 263.1 DDIT4 Dig2, FLJ20500, REDD-1, REDD1, RTP801 ENSG00000168209 DNA-damage-inducible transcript 4 10 72273920-72276036 Predicted intracellular proteins Evidence at protein level HPA034507, HPA034508 Approved Supported Cytosol Renal cancer:2.54e-6 (unfavourable), Pancreatic cancer:2.78e-4 (unfavourable), Head and neck cancer:5.42e-4 (unfavourable) Expressed in all Expressed in all ovary: 220.2 DDOST KIAA0115, OST, OST48, WBP1 ENSG00000244038 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 1 20651767-20661544 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009746, HPA046841, HPA052867 Supported Supported Endoplasmic reticulum Renal cancer:9.05e-7 (unfavourable), Liver cancer:2.64e-5 (unfavourable), Head and neck cancer:4.88e-4 (unfavourable), Endometrial cancer:5.99e-4 (favourable) Expressed in all Expressed in all thyroid gland: 307.5 DDRGK1 C20orf116, dJ1187M17.3 ENSG00000198171 DDRGK domain containing 1 20 3190350-3204685 Predicted intracellular proteins Evidence at protein level HPA013373, HPA013705 Approved Supported Nucleoli
Endoplasmic reticulum Renal cancer:2.01e-5 (favourable) Expressed in all Expressed in all adrenal gland: 72.7 DDT DDCT ENSG00000099977 D-dopachrome tautomerase 22 23971365-23980469 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049871 Approved Approved Mitochondria Expressed in all Expressed in all liver: 109.2 DDX1 DBP-RB ENSG00000079785 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2 15591178-15631111 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012280, HPA034502, HPA034503 Supported Validated Nucleoplasm
Cytosol Liver cancer:9.09e-9 (unfavourable), Renal cancer:9.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 143.2 DDX10 HRH-J8 ENSG00000178105 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 11 108665025-108940930 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA004691 Approved Approved Nucleoli Renal cancer:2.14e-5 (favourable), Liver cancer:2.52e-5 (unfavourable), Pancreatic cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all testis: 29.1 DDX11 CHL1, CHLR1, KRG2, WABS ENSG00000013573 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 12 31073845-31104791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA065197 Supported Supported Nucleus
Nucleoli Renal cancer:5.23e-8 (unfavourable), Liver cancer:2.40e-4 (unfavourable) Expressed in all Expressed in all skin: 19.3 DDX17 P72 ENSG00000100201 DEAD (Asp-Glu-Ala-Asp) box helicase 17 22 38483440-38507660 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB024908, HPA063142 Supported Validated Nuclear speckles Lung cancer:6.06e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 328.9 DDX18 MrDb ENSG00000088205 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2 117814650-117832379 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035400, HPA041056 Approved Validated Nucleoli Endometrial cancer:2.64e-4 (unfavourable), Liver cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.4 DDX19A DDX19L, FLJ11126 ENSG00000168872 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 16 70346829-70373383 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA045252, HPA066668 Approved Uncertain Nucleoplasm Liver cancer:8.05e-5 (unfavourable), Head and neck cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.2 DDX19B DBP5, DDX19 ENSG00000157349 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 16 70289663-70335283 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB037229, CAB037284, HPA046380, HPA066668 Approved Uncertain Nucleoplasm Expressed in all Expressed in all testis: 82.7 DDX21 GURDB, RH-II/GU ENSG00000165732 DEAD (Asp-Glu-Ala-Asp) box helicase 21 10 68956128-68985073 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036592, HPA036593 Supported Validated Nucleus
Nucleoli Pancreatic cancer:3.12e-4 (unfavourable) Expressed in all Expressed in all appendix: 73.1 DDX23 prp28, PRPF28, SNRNP100, U5-100K ENSG00000174243 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 12 48829764-48852842 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038680, HPA039037 Approved Supported Nucleus
Nucleoli Liver cancer:3.03e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 57.3 DDX27 dJ686N3.1, DRS1 ENSG00000124228 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 20 49219295-49244077 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047087 Uncertain Approved Nucleoli Liver cancer:6.70e-7 (unfavourable), Endometrial cancer:1.44e-5 (unfavourable), Renal cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all testis: 46.1 DDX28 FLJ11282, MDDX28 ENSG00000182810 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 16 68021274-68023442 Enzymes, Predicted secreted proteins Evidence at protein level HPA041911, HPA053585 Approved Supported Nucleoli
Mitochondria
Cytosol Renal cancer:2.07e-10 (favourable) Expressed in all Expressed in all bone marrow: 11.2 DDX31 FLJ13633, FLJ14578, FLJ23349, PPP1R25 ENSG00000125485 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 9 132592997-132670401 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020891 Supported Nucleoli
Golgi apparatus
Vesicles Liver cancer:1.68e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 23.0 DDX39A BAT1L, DDX39, DDXL, URH49 ENSG00000123136 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 19 14408819-14419383 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055334 Approved Approved Nuclear speckles Renal cancer:1.50e-10 (unfavourable), Cervical cancer:6.86e-4 (favourable) Expressed in all Expressed in all testis: 209.6 DDX39B BAT1, D6S81E, UAP56 ENSG00000198563 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 6 31530219-31542448 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB034012, HPA055334, HPA058450 Supported Validated Nuclear speckles Renal cancer:1.11e-6 (unfavourable), Urothelial cancer:1.43e-5 (favourable) Expressed in all Expressed in all epididymis: 44.0 DDX3X DBX, DDX14, DDX3, HLP2 ENSG00000215301 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked X 41333348-41364472 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA001648, HPA005631, HPA059585 Supported Approved Approved Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 270.3 DDX41 ABS, MGC8828 ENSG00000183258 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 5 177511577-177517469 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017911, HPA048803 Supported Supported Nucleus Renal cancer:2.21e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 52.7 DDX42 RHELP, RNAHP, SF3b125, SF3B8 ENSG00000198231 DEAD (Asp-Glu-Ala-Asp) box helicase 42 17 63773603-63819317 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023447, HPA023571, HPA025941 Supported Validated Nuclear speckles Liver cancer:2.84e-4 (unfavourable), Renal cancer:9.26e-4 (unfavourable) Expressed in all Expressed in all testis: 74.1 DDX46 FLJ25329, KIAA0801, Prp5, PRPF5 ENSG00000145833 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 5 134758771-134855133 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036554, HPA057501 Supported Validated Nuclear speckles Colorectal cancer:9.01e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 36.2 DDX47 DKFZp564O176, FLJ30012, HQ0256, RRP3 ENSG00000213782 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 12 12813316-12829981 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014855 Approved Validated Nucleoli Mixed Expressed in all thyroid gland: 55.5 DDX49 FLJ10432 ENSG00000105671 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 19 18919675-18928633 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041870, HPA048093 Approved Approved Nucleoli
Mitochondria Cervical cancer:2.01e-6 (favourable), Renal cancer:7.44e-5 (unfavourable), Liver cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all testis: 24.4 DDX5 G17P1, HLR1, p68 ENSG00000108654 DEAD (Asp-Glu-Ala-Asp) box helicase 5 17 64499616-64508199 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005868, HPA020043 Supported Validated Nucleoplasm Colorectal cancer:2.12e-4 (favourable) Expressed in all Expressed in all smooth muscle: 594.4 DDX50 GU2, GUB, MGC3199, RH-II/GuB ENSG00000107625 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 10 68901278-68946847 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037388, HPA037389, HPA058196 Approved Validated Nucleoli Expressed in all Expressed in all testis: 46.9 DDX51 ENSG00000185163 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 12 132136594-132144335 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039503 Uncertain Approved Nucleus
Nucleoli
Cytosol Liver cancer:4.73e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 11.4 DDX54 APR-5, DP97, MGC2835 ENSG00000123064 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 12 113157174-113185479 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028244, HPA070786 Approved Approved Nucleus
Nucleoli
Golgi apparatus Liver cancer:1.39e-4 (unfavourable) Expressed in all Expressed in all appendix: 40.2 DDX55 KIAA1595 ENSG00000111364 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 12 123602077-123620941 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039962, HPA044101 Approved Supported Nucleus
Nucleoli
Cytosol Renal cancer:8.97e-12 (unfavourable), Liver cancer:2.11e-9 (unfavourable) Expressed in all Expressed in all skin: 16.5 DDX56 NOH61 ENSG00000136271 DEAD (Asp-Glu-Ala-Asp) box helicase 56 7 44565417-44575051 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019749 Uncertain Renal cancer:8.41e-7 (unfavourable), Liver cancer:1.38e-5 (unfavourable) Expressed in all Expressed in all skin: 5.6 DDX58 DKFZp434J1111, FLJ13599, RIG-I ENSG00000107201 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 9 32455705-32526324 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB012643, HPA047193 Uncertain Supported Cytosol Renal cancer:4.66e-4 (unfavourable), Endometrial cancer:5.46e-4 (unfavourable) Expressed in all Expressed in all spleen: 20.2 DDX59 DKFZP564B1023, ZNHIT5 ENSG00000118197 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 1 200623896-200669969 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA047166 Approved Approved Nucleus
Actin filaments Renal cancer:9.02e-4 (unfavourable) Expressed in all Expressed in all breast: 33.2 DDX6 HLR2, RCK ENSG00000110367 DEAD (Asp-Glu-Ala-Asp) box helicase 6 11 118747766-118791149 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004668, HPA024201, HPA026644 Approved Supported Cytosol
Cytoplasmic bodies Liver cancer:6.56e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 65.6 DEAF1 NUDR, SPN, ZMYND5 ENSG00000177030 DEAF1 transcription factor 11 644233-706715 Disease related genes, Predicted secreted proteins, Transcription factors Evidence at protein level HPA030302 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 40.8 DECR1 DECR, SDR18C1 ENSG00000104325 2,4-dienoyl CoA reductase 1, mitochondrial 8 90001405-90052092 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023160, HPA023162, HPA023238 Supported Supported Mitochondria
Cytosol Renal cancer:1.79e-7 (favourable), Breast cancer:1.49e-4 (unfavourable), Urothelial cancer:6.06e-4 (favourable) Expressed in all Expressed in all liver: 262.7 DEDD CASP8IP1, DEDD1, DEFT, FLDED1, KE05 ENSG00000158796 Death effector domain containing 1 161120974-161132688 Predicted intracellular proteins Evidence at protein level HPA030681 Uncertain Nucleus Renal cancer:4.98e-7 (unfavourable), Liver cancer:8.48e-4 (unfavourable) Expressed in all Expressed in all testis: 47.4 DEF8 FLJ20186 ENSG00000140995 Differentially expressed in FDCP 8 homolog (mouse) 16 89947925-89968060 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041745, HPA049434 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.95e-8 (favourable), Pancreatic cancer:1.35e-7 (favourable) Expressed in all Expressed in all lymph node: 90.4 DEGS1 DEGS-1, Des-1, DES1, FADS7, MLD ENSG00000143753 Delta(4)-desaturase, sphingolipid 1 1 224175756-224193441 Enzymes, Predicted membrane proteins Evidence at protein level HPA076422 Supported Mitochondria Renal cancer:6.83e-7 (unfavourable), Liver cancer:4.29e-5 (unfavourable), Endometrial cancer:7.74e-5 (unfavourable), Urothelial cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all skin: 617.7 DEK D6S231E ENSG00000124795 DEK proto-oncogene 6 18223868-18264823 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015226, HPA054505, HPA057799 Supported Validated Nucleus Renal cancer:3.45e-4 (unfavourable), Liver cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 158.3 DENND1A FAM31A, FLJ21129, KIAA1608 ENSG00000119522 DENN/MADD domain containing 1A 9 123379654-123930152 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020481 Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:4.11e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.5 DENND1B C1orf218, FAM31B, FLJ20054, MGC27044 ENSG00000213047 DENN/MADD domain containing 1B 1 197504748-197775696 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042586 Uncertain Supported Nuclear speckles
Cytosol Expressed in all Expressed in all parathyroid gland: 11.5 DENND4A IRLB, MYCPBP ENSG00000174485 DENN/MADD domain containing 4A 15 65658046-65792293 Predicted intracellular proteins Evidence at protein level HPA065343 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 24.8 DENND4B KIAA0476 ENSG00000198837 DENN/MADD domain containing 4B 1 153929501-153946696 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040188 Approved Nucleus
Golgi apparatus Renal cancer:9.27e-9 (unfavourable), Pancreatic cancer:3.18e-5 (favourable), Liver cancer:4.14e-4 (unfavourable) Expressed in all Expressed in all spleen: 40.9 DENND4C bA513M16.3, C9orf55, C9orf55B, FLJ20686 ENSG00000137145 DENN/MADD domain containing 4C 9 19230435-19373545 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014917, HPA015096 Approved Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:3.51e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 47.3 DENND5A FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1 ENSG00000184014 DENN/MADD domain containing 5A 11 9138825-9265390 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052923, HPA055009 Uncertain Approved Golgi apparatus
Vesicles Renal cancer:1.14e-6 (unfavourable), Liver cancer:5.05e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 127.2 DENND6A AFI1A, FAM116A, FLJ34969 ENSG00000174839 DENN/MADD domain containing 6A 3 57625457-57693089 Predicted intracellular proteins Evidence at protein level HPA062618, HPA069725, HPA071711 Approved Supported Vesicles Renal cancer:7.77e-6 (favourable), Liver cancer:6.36e-4 (unfavourable), Colorectal cancer:9.21e-4 (favourable) Expressed in all Expressed in all ovary: 25.5 DENR DRP, DRP1, SMAP-3 ENSG00000139726 Density-regulated protein 12 122752774-122771064 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021783 Approved Approved Cytosol Liver cancer:1.58e-7 (unfavourable), Renal cancer:8.57e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 106.8 DEPTOR DEP.6, DEPDC6, FLJ12428 ENSG00000155792 DEP domain containing MTOR-interacting protein 8 119873717-120050913 Predicted intracellular proteins Evidence at protein level CAB020841, HPA023938, HPA023945, HPA024011 Supported Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all thyroid gland: 163.3 DERA CGI-26, DEOC ENSG00000023697 Deoxyribose-phosphate aldolase (putative) 12 15911172-16037282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055897 Supported Nucleus Thyroid cancer:3.64e-5 (favourable), Pancreatic cancer:1.32e-4 (unfavourable) Expressed in all Expressed in all kidney: 74.2 DERL1 DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577 ENSG00000136986 Derlin 1 8 123013164-123042423 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016562, CAB037269 Supported Validated Endoplasmic reticulum Endometrial cancer:5.66e-5 (unfavourable), Renal cancer:1.58e-4 (unfavourable), Breast cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 76.6 DERL2 CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa ENSG00000072849 Derlin 2 17 5471251-5486811 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037287, HPA048957, HPA056551 Supported Supported Endoplasmic reticulum Renal cancer:6.49e-4 (unfavourable), Endometrial cancer:7.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.3 DESI1 D15Wsu75e, FAM152B, PPPDE2 ENSG00000100418 Desumoylating isopeptidase 1 22 41598028-41621096 Predicted intracellular proteins Evidence at protein level HPA053415 Approved Approved Cytokinetic bridge
Cytosol Endometrial cancer:7.70e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.6 DESI2 C1orf121, CGI-146, FAM152A, FLJ21998, PNAS-4, PPPDE1 ENSG00000121644 Desumoylating isopeptidase 2 1 244652935-244709033 Predicted intracellular proteins Evidence at protein level HPA049950 Approved Vesicles Renal cancer:4.25e-5 (unfavourable) Expressed in all Expressed in all testis: 94.5 DEXI MYLE ENSG00000182108 Dexi homolog (mouse) 16 10928891-10942460 Predicted membrane proteins Evidence at transcript level HPA041511 Approved Approved Nuclear speckles
Cytosol Pancreatic cancer:4.23e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 45.0 DFFA DFF-45, DFF1, DFF45, ICAD ENSG00000160049 DNA fragmentation factor, 45kDa, alpha polypeptide 1 10456522-10472526 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002679, HPA018859, HPA019938, HPA025230 Supported Supported Plasma membrane
Cytosol Renal cancer:1.57e-9 (favourable), Liver cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all placenta: 28.8 DGCR2 DGS-C, IDD, KIAA0163, LAN, SEZ-12 ENSG00000070413 DiGeorge syndrome critical region gene 2 22 19036282-19122454 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA000873, HPA075929 Uncertain Approved Nucleoplasm
Nuclear bodies Renal cancer:8.72e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 58.4 DGCR6L FLJ10666 ENSG00000128185 DiGeorge syndrome critical region gene 6-like 22 20314276-20320080 Predicted intracellular proteins Evidence at protein level Cervical cancer:3.82e-5 (favourable), Lung cancer:5.37e-4 (favourable) Expressed in all Expressed in all testis: 97.0 DGCR8 C22orf12, DGCRK6, Gy1, pasha ENSG00000128191 DGCR8 microprocessor complex subunit 22 20080232-20111877 Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:1.08e-4 (unfavourable), Renal cancer:5.67e-4 (unfavourable) Expressed in all Expressed in all testis: 22.1 DGKQ DAGK, DAGK4, DAGK7 ENSG00000145214 Diacylglycerol kinase, theta 110kDa 4 958887-986895 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026797, CAB033835 Uncertain Expressed in all Expressed in all small intestine: 26.6 DGKZ DAGK5, DAGK6, DGK-ZETA, hDGKzeta ENSG00000149091 Diacylglycerol kinase, zeta 11 46332905-46380554 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051336 Supported Supported Nuclear speckles Renal cancer:4.74e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 133.0 DGUOK dGK ENSG00000114956 Deoxyguanosine kinase 2 73926826-73958961 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA034766, HPA057246 Approved Renal cancer:8.69e-7 (unfavourable), Urothelial cancer:7.47e-4 (favourable) Expressed in all Expressed in all testis: 56.4 DHCR24 DCE, KIAA0018, seladin-1 ENSG00000116133 24-dehydrocholesterol reductase 1 54849633-54887218 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037247, HPA063005 Approved Endometrial cancer:1.05e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 1100.8 DHCR7 SLOS ENSG00000172893 7-dehydrocholesterol reductase 11 71428193-71452868 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA044280 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:6.93e-7 (favourable), Urothelial cancer:5.67e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 116.0 DHDDS DS, FLJ13102, HDS, RP59 ENSG00000117682 Dehydrodolichyl diphosphate synthase subunit 1 26432282-26471294 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026721, HPA026727 Uncertain Uncertain Plasma membrane Renal cancer:4.08e-7 (favourable) Expressed in all Expressed in all adipose tissue: 54.6 DHPS MIG13 ENSG00000095059 Deoxyhypusine synthase 19 12675717-12681902 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014461, HPA029413 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all fallopian tube: 63.4 DHRS1 FLJ25430, MGC20204, SDR19C1 ENSG00000157379 Dehydrogenase/reductase (SDR family) member 1 14 24290598-24299833 Predicted intracellular proteins Evidence at protein level HPA000599 Approved Approved Nucleus
Centrosome
Cytosol Liver cancer:1.18e-5 (favourable), Lung cancer:6.83e-4 (favourable) Expressed in all Expressed in all esophagus: 78.6 DHRS12 FLJ13639, SDR40C1 ENSG00000102796 Dehydrogenase/reductase (SDR family) member 12 13 51767993-51804157 Predicted intracellular proteins Evidence at protein level CAB034238, HPA057028, HPA058315 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:2.22e-16 (favourable), Breast cancer:1.41e-4 (favourable) Expressed in all Expressed in all epididymis: 22.6 DHRS3 RDH17, retSDR1, Rsdr1, SDR1, SDR16C1 ENSG00000162496 Dehydrogenase/reductase (SDR family) member 3 1 12567910-12617731 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010844 Supported Approved Nucleoli
Mitochondria Thyroid cancer:2.65e-4 (favourable) Expressed in all Expressed in all adipose tissue: 99.6 DHRS4 FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2 ENSG00000157326 Dehydrogenase/reductase (SDR family) member 4 14 23953586-23969279 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023972 Uncertain Approved Nuclear membrane
Vesicles Renal cancer:4.55e-6 (favourable) Expressed in all Expressed in all kidney: 149.2 DHRS4L2 SDR25C3 ENSG00000187630 Dehydrogenase/reductase (SDR family) member 4 like 2 14 23969874-24006408 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023972 Uncertain Uncertain Nuclear membrane
Vesicles Ovarian cancer:3.21e-4 (favourable) Expressed in all Expressed in all kidney: 121.8 DHRS7 retDSR4, SDR34C1 ENSG00000100612 Dehydrogenase/reductase (SDR family) member 7 14 60144120-60169856 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031121 Approved Approved Nucleoplasm
Mitochondria Renal cancer:1.92e-10 (favourable), Head and neck cancer:2.51e-4 (unfavourable), Breast cancer:6.42e-4 (favourable), Ovarian cancer:7.99e-4 (unfavourable) Tissue enriched Expressed in all prostate: 656.8 DHRS7B CGI-93, DKFZp566O084, MGC8916, SDR32C1 ENSG00000109016 Dehydrogenase/reductase (SDR family) member 7B 17 21123364-21193265 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012132, HPA016873 Uncertain Approved Plasma membrane
Cell Junctions
Cytosol Endometrial cancer:1.98e-8 (favourable), Renal cancer:3.95e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 49.4 DHRSX DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6 ENSG00000169084 Dehydrogenase/reductase (SDR family) X-linked X 2219516-2502805 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003035 Approved Approved Actin filaments
Cytosol Expressed in all Expressed in all thyroid gland: 17.0 DHTKD1 CMT2Q, DKFZP762M115, KIAA1630, MGC3090 ENSG00000181192 Dehydrogenase E1 and transketolase domain containing 1 10 12068972-12123225 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037949, HPA037950, HPA066098 Approved Supported Mitochondria Renal cancer:3.43e-4 (favourable) Expressed in all Expressed in all liver: 66.5 DHX15 DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p ENSG00000109606 DEAH (Asp-Glu-Ala-His) box helicase 15 4 24517441-24584550 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047047 Approved Validated Nuclear speckles Colorectal cancer:5.74e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 100.9 DHX29 DDX29 ENSG00000067248 DEAH (Asp-Glu-Ala-His) box polypeptide 29 5 55256245-55307722 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038317, HPA038318 Uncertain Approved Cytosol Expressed in all Expressed in all parathyroid gland: 38.0 DHX30 DDX30, FLJ11214, KIAA0890 ENSG00000132153 DEAH (Asp-Glu-Ala-His) box helicase 30 3 47802909-47850195 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034806 Supported Supported Mitochondria
Cytosol Renal cancer:1.37e-6 (favourable) Expressed in all Expressed in all testis: 46.7 DHX32 DDX32, DHLP1, FLJ10694, FLJ10889 ENSG00000089876 DEAH (Asp-Glu-Ala-His) box polypeptide 32 10 125836337-125896436 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048872 Approved Pancreatic cancer:9.49e-5 (unfavourable), Prostate cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all testis: 59.6 DHX33 DDX33, DKFZp762F2011, FLJ21972 ENSG00000005100 DEAH (Asp-Glu-Ala-His) box polypeptide 33 17 5440912-5469060 Enzymes, Predicted intracellular proteins Evidence at protein level HPA073875 Supported Nucleoli Prostate cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 13.5 DHX36 DDX36, KIAA1488, MLEL1 ENSG00000174953 DEAH (Asp-Glu-Ala-His) box polypeptide 36 3 154272546-154324497 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035399 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all testis: 63.0 DHX38 DDX38, hPrp16, KIAA0224, PRP16, PRPF16 ENSG00000140829 DEAH (Asp-Glu-Ala-His) box polypeptide 38 16 72093562-72112912 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041347, HPA041604 Uncertain Supported Nucleus Expressed in all Expressed in all parathyroid gland: 49.8 DHX40 ARG147, DDX40, FLJ22060, PAD ENSG00000108406 DEAH (Asp-Glu-Ala-His) box polypeptide 40 17 59565525-59608345 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044350 Uncertain Supported Nucleus Colorectal cancer:4.05e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 88.1 DHX58 D11LGP2, LGP2 ENSG00000108771 DEXH (Asp-Glu-X-His) box polypeptide 58 17 42101404-42112733 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018670, HPA019570 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Breast cancer:3.45e-4 (favourable) Expressed in all Expressed in all spleen: 25.3 DHX8 DDX8, HRH1, PRP22, PRPF22 ENSG00000067596 DEAH (Asp-Glu-Ala-His) box polypeptide 8 17 43483865-43544463 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA049285 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 54.2 DHX9 DDX9, LKP, RHA ENSG00000135829 DEAH (Asp-Glu-Ala-His) box helicase 9 1 182839369-182887751 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011819, HPA028050, HPA055684 Supported Validated Nucleus Liver cancer:3.17e-4 (unfavourable), Melanoma:6.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 135.7 DIABLO DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC ENSG00000184047 Diablo, IAP-binding mitochondrial protein 12 122207662-122227534 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001825, CAB003857, CAB016688 Supported Validated Mitochondria Renal cancer:5.35e-4 (unfavourable) Expressed in all Expressed in all testis: 94.5 DIAPH1 DFNA1, hDIA1, LFHL1 ENSG00000131504 Diaphanous-related formin 1 5 141515016-141619055 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004916, HPA076913 Approved Approved Plasma membrane Renal cancer:1.29e-5 (favourable), Pancreatic cancer:7.81e-5 (unfavourable) Expressed in all Expressed in all lymph node: 73.7 DIAPH2 DIA, DIA2, POF, POF2 ENSG00000147202 Diaphanous-related formin 2 X 96684663-97604997 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005647, CAB015461, CAB068183, CAB068184 Supported Supported Nucleoli
Endoplasmic reticulum
Vesicles Endometrial cancer:2.16e-5 (unfavourable), Pancreatic cancer:2.12e-4 (unfavourable), Renal cancer:3.90e-4 (unfavourable) Expressed in all Expressed in all placenta: 17.6 DICER1 Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1 ENSG00000100697 Dicer 1, ribonuclease type III 14 95086228-95158010 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000694, CAB068185 Approved Supported Cytosol Expressed in all Expressed in all placenta: 32.2 DIDO1 BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333 ENSG00000101191 Death inducer-obliterator 1 20 62877738-62937952 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004374, HPA049904 Supported Approved Nucleoplasm
Vesicles Pancreatic cancer:3.88e-4 (favourable), Head and neck cancer:5.13e-4 (favourable) Expressed in all Expressed in all fallopian tube: 47.7 DIMT1 DIMT1L, HSA9761 ENSG00000086189 DIM1 dimethyladenosine transferase 1 homolog 5 62387254-62403939 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042944 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:8.90e-12 (unfavourable), Liver cancer:6.93e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 33.8 DIP2A C21orf106, Dip2, KIAA0184 ENSG00000160305 Disco-interacting protein 2 homolog A 21 46458899-46569852 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052516 Uncertain Approved Nucleus Head and neck cancer:9.35e-5 (favourable) Expressed in all Expressed in all testis: 13.9 DIP2B FLJ34278, KIAA1463 ENSG00000066084 Disco-interacting protein 2 homolog B 12 50504985-50748667 Predicted intracellular proteins Evidence at protein level HPA038472, HPA046133, HPA056045 Approved Approved Endoplasmic reticulum Breast cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 31.1 DIRC2 FLJ14784, RCC4 ENSG00000138463 Disrupted in renal carcinoma 2 3 122794795-122881139 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA072579 Supported Vesicles Renal cancer:8.81e-11 (favourable), Pancreatic cancer:5.81e-5 (unfavourable), Liver cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 15.9 DIS3 dis3p, EXOSC11, KIAA1008, RRP44 ENSG00000083520 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 13 72752169-72782096 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039281, HPA058762 Approved Validated Nucleus
Cytosol Expressed in all Expressed in all testis: 38.5 DIS3L DIS3L1, FLJ38088, KIAA1955, MGC4562 ENSG00000166938 DIS3 like exosome 3'-5' exoribonuclease 15 66293217-66333898 Predicted intracellular proteins Evidence at protein level HPA041805 Approved Approved Plasma membrane
Centrosome
Cytosol Expressed in all Expressed in all parathyroid gland: 26.1 DIS3L2 FAM6A, FLJ36974, MGC42174 ENSG00000144535 DIS3 like 3'-5' exoribonuclease 2 2 231961245-232344350 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035796, HPA035797 Approved Liver cancer:3.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.8 DKC1 DKC, dyskerin, NAP57, NOLA4, XAP101 ENSG00000130826 Dyskeratosis congenita 1, dyskerin X 154762742-154777689 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000166, HPA000447, HPA001022, CAB033086 Supported Supported Nucleus
Nucleoli fibrillar center Renal cancer:1.46e-9 (unfavourable), Liver cancer:1.39e-5 (unfavourable), Endometrial cancer:2.66e-5 (unfavourable), Head and neck cancer:2.94e-4 (unfavourable), Melanoma:9.13e-4 (unfavourable) Expressed in all Expressed in all lymph node: 45.7 DLAT DLTA, PDC-E2 ENSG00000150768 Dihydrolipoamide S-acetyltransferase 11 112024814-112064390 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003782, HPA040786, HPA062766 Supported Validated Mitochondria Renal cancer:1.95e-14 (favourable), Colorectal cancer:6.19e-6 (favourable), Liver cancer:7.49e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 31.8 DLC1 ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12 ENSG00000164741 DLC1 Rho GTPase activating protein 8 13083361-13604610 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017753 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Endometrial cancer:1.11e-4 (favourable) Expressed in all Expressed in all lung: 78.7 DLD DLDH, GCSL, LAD ENSG00000091140 Dihydrolipoamide dehydrogenase 7 107890970-107931730 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044849 Supported Supported Mitochondria Renal cancer:7.58e-9 (favourable) Expressed in all Expressed in all kidney: 119.6 DLG1 dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97 ENSG00000075711 Discs, large homolog 1 (Drosophila) 3 197042560-197299300 Predicted intracellular proteins Evidence at protein level CAB016307, HPA069593 Supported Uncertain Vesicles
Plasma membrane Expressed in all Expressed in all thyroid gland: 94.5 DLGAP4 DAP4, KIAA0964, SAPAP4 ENSG00000080845 Discs, large (Drosophila) homolog-associated protein 4 20 36306336-36528637 Predicted intracellular proteins Evidence at protein level HPA054105, HPA056378 Approved Approved Nucleoplasm
Focal adhesion sites
Cytosol Liver cancer:3.73e-6 (unfavourable), Endometrial cancer:2.24e-5 (unfavourable), Melanoma:9.88e-5 (favourable), Renal cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 60.9 DLST DLTS ENSG00000119689 Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 14 74881891-74903745 Citric acid cycle related proteins, Enzymes, Predicted intracellular proteins Evidence at protein level HPA003010 Supported Renal cancer:1.13e-12 (favourable) Expressed in all Expressed in all kidney: 106.0 DMAP1 DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4 ENSG00000178028 DNA methyltransferase 1 associated protein 1 1 44213455-44220681 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028419, CAB033018 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 40.5 DMPK DM, DM1, DM1PK, DMK, MDPK, MT-PK ENSG00000104936 Dystrophia myotonica-protein kinase 19 45769717-45782552 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007164, HPA008905 Supported Approved Vesicles
Cytosol Pancreatic cancer:9.39e-5 (favourable) Expressed in all Expressed in all smooth muscle: 96.5 DMTF1 DMP1, DMTF, hDMP1, MRUL ENSG00000135164 Cyclin D binding myb-like transcription factor 1 7 87152361-87196337 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023846 Supported Supported Nucleoplasm Renal cancer:4.39e-5 (unfavourable) Expressed in all Expressed in all testis: 83.7 DMTN DMT, EPB49 ENSG00000158856 Dematin actin binding protein 8 22048995-22082527 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024290 Uncertain Renal cancer:3.85e-9 (favourable), Glioma:4.61e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 222.1 DMWD D19S593E, DMR-N9, gene59 ENSG00000185800 Dystrophia myotonica, WD repeat containing 19 45782947-45792802 Predicted intracellular proteins Evidence at protein level HPA068172, HPA069843 Approved Approved Plasma membrane
Actin filaments Liver cancer:1.47e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.8 DNAAF2 C14orf104, CILD10, FLJ10563, KTU, PF13 ENSG00000165506 Dynein, axonemal, assembly factor 2 14 49625174-49635230 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002894, HPA004113 Approved Supported Cytosol Renal cancer:6.74e-7 (favourable) Expressed in all Expressed in all fallopian tube: 13.8 DNAAF5 CILD18, FLJ20397, FLJ25564, FLJ31671, FLJ39381, HEATR2 ENSG00000164818 Dynein, axonemal, assembly factor 5 7 726701-786475 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020243 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:3.83e-4 (unfavourable), Head and neck cancer:8.42e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 22.6 DNAJA1 dj-2, hdj-2, HSJ2, HSPF4, NEDD7 ENSG00000086061 DnaJ (Hsp40) homolog, subfamily A, member 1 9 33025211-33039907 Predicted intracellular proteins Evidence at protein level HPA001306 Approved Supported Microtubules
Cytosol Renal cancer:3.40e-4 (favourable), Ovarian cancer:5.39e-4 (favourable) Expressed in all Expressed in all testis: 240.2 DNAJA2 CPR3, DNAJ, DNJ3, HIRIP4 ENSG00000069345 DnaJ (Hsp40) homolog, subfamily A, member 2 16 46955362-46973788 Predicted intracellular proteins Evidence at protein level HPA049789, HPA060538 Approved Approved Nucleoli
Intermediate filaments
Cytosol Renal cancer:1.19e-9 (favourable), Head and neck cancer:2.81e-4 (unfavourable) Expressed in all Expressed in all testis: 41.8 DNAJA3 hTid-1, TID1 ENSG00000103423 DnaJ (Hsp40) homolog, subfamily A, member 3 16 4425805-4456775 Predicted intracellular proteins Evidence at protein level CAB016095, HPA040875, HPA044229 Approved Supported Mitochondria Renal cancer:1.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.8 DNAJA4 PRO1472 ENSG00000140403 DnaJ (Hsp40) homolog, subfamily A, member 4 15 78264086-78282196 Predicted intracellular proteins Evidence at protein level CAB004646, HPA041790 Uncertain Approved Plasma membrane
Cytosol Renal cancer:1.08e-7 (favourable), Glioma:8.35e-4 (unfavourable) Expressed in all Expressed in all testis: 95.2 DNAJB1 Hsp40, HSPF1, RSPH16B, Sis1 ENSG00000132002 DnaJ (Hsp40) homolog, subfamily B, member 1 19 14514770-14529770 Predicted intracellular proteins Evidence at protein level CAB017450, HPA063247 Supported Validated Nucleus
Cytosol Renal cancer:5.96e-4 (favourable) Expressed in all Expressed in all adrenal gland: 351.6 DNAJB11 EDJ, ERdj3, HEDJ ENSG00000090520 DnaJ (Hsp40) homolog, subfamily B, member 11 3 186567403-186597203 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010814, HPA017051 Supported Supported Endoplasmic reticulum Renal cancer:3.44e-9 (unfavourable) Expressed in all Expressed in all thyroid gland: 111.3 DNAJB12 DJ10, FLJ20027 ENSG00000148719 DnaJ (Hsp40) homolog, subfamily B, member 12 10 72332830-72355230 Predicted membrane proteins Evidence at protein level HPA010642 Approved Supported Endoplasmic reticulum Colorectal cancer:4.79e-4 (unfavourable), Head and neck cancer:8.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 47.2 DNAJB14 FLJ14281 ENSG00000164031 DnaJ (Hsp40) homolog, subfamily B, member 14 4 99896248-99946726 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036016 Approved Renal cancer:2.12e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 34.8 DNAJB2 CMT2T, HSJ1, HSPF3 ENSG00000135924 DnaJ (Hsp40) homolog, subfamily B, member 2 2 219279267-219286900 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036268 Approved Validated Nuclear membrane Colorectal cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 162.3 DNAJB4 HLJ1 ENSG00000162616 DnaJ (Hsp40) homolog, subfamily B, member 4 1 77979175-78017964 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004995, HPA028383, HPA028385 Approved Validated Nucleoplasm
Plasma membrane
Cytosol Renal cancer:2.28e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 74.0 DNAJB6 LGMD1D, MRJ ENSG00000105993 DnaJ (Hsp40) homolog, subfamily B, member 6 7 157335381-157417439 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004670, HPA024258, HPA058593 Supported Supported Nucleoplasm Liver cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all testis: 219.6 DNAJB9 MDG1 ENSG00000128590 DnaJ (Hsp40) homolog, subfamily B, member 9 7 108569568-108574850 Predicted secreted proteins Evidence at protein level HPA040967, HPA041553 Supported Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all thyroid gland: 113.1 DNAJC1 DNAJL1, ERdj1, MTJ1 ENSG00000136770 DnaJ (Hsp40) homolog, subfamily C, member 1 10 21756537-22003769 Predicted membrane proteins, Transcription factors Evidence at protein level HPA013432 Approved Approved Endoplasmic reticulum Liver cancer:1.96e-5 (unfavourable), Renal cancer:2.33e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.8 DNAJC10 ERdj5, PDIA19 ENSG00000077232 DnaJ (Hsp40) homolog, subfamily C, member 10 2 182716041-182794464 Predicted membrane proteins Evidence at protein level HPA031111 Approved Renal cancer:2.19e-7 (unfavourable), Endometrial cancer:6.42e-5 (favourable), Thyroid cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all epididymis: 152.2 DNAJC11 FLJ10737 ENSG00000007923 DnaJ (Hsp40) homolog, subfamily C, member 11 1 6634168-6701924 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028705 Uncertain Approved Cytosol Renal cancer:2.63e-5 (favourable) Expressed in all Expressed in all kidney: 38.2 DNAJC13 KIAA0678, RME8 ENSG00000138246 DnaJ (Hsp40) homolog, subfamily C, member 13 3 132417526-132539032 Disease related genes, Predicted membrane proteins Evidence at protein level HPA036923, HPA036924 Approved Supported Vesicles
Cytosol Liver cancer:7.49e-4 (unfavourable), Pancreatic cancer:8.36e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.8 DNAJC14 DNAJ, DRIP78, FLJ32792, HDJ3, LIP6 ENSG00000135392 DnaJ (Hsp40) homolog, subfamily C, member 14 12 55820960-55830824 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017653 Approved Expressed in all Expressed in all parathyroid gland: 49.6 DNAJC16 KIAA0962 ENSG00000116138 DnaJ (Hsp40) homolog, subfamily C, member 16 1 15526813-15592379 Predicted membrane proteins Evidence at protein level HPA043643 Approved Approved Vesicles Colorectal cancer:6.77e-4 (favourable), Renal cancer:7.24e-4 (favourable) Expressed in all Expressed in all kidney: 20.8 DNAJC17 FLJ10634 ENSG00000104129 DnaJ (Hsp40) homolog, subfamily C, member 17 15 40765155-40807478 Predicted intracellular proteins Evidence at protein level HPA040914, HPA041187 Approved Approved Nucleoplasm Colorectal cancer:5.89e-4 (unfavourable) Expressed in all Expressed in all endometrium: 24.2 DNAJC19 Pam18, Tim14, TIMM14 ENSG00000205981 DnaJ (Hsp40) homolog, subfamily C, member 19 3 180983709-180989774 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037782 Approved Ovarian cancer:8.53e-5 (favourable) Expressed in all Expressed in all kidney: 52.6 DNAJC2 MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin ENSG00000105821 DnaJ (Hsp40) homolog, subfamily C, member 2 7 103312474-103344873 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020454 Approved Supported Cytosol Renal cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all testis: 61.7 DNAJC21 DNAJA5, GS3, JJJ1 ENSG00000168724 DnaJ (Hsp40) homolog, subfamily C, member 21 5 34929593-34958964 Predicted intracellular proteins Evidence at protein level HPA040789, HPA049208 Approved Approved Vesicles Liver cancer:2.36e-5 (unfavourable) Expressed in all Expressed in all testis: 101.2 DNAJC24 DPH4, JJJ3, ZCSL3 ENSG00000170946 DnaJ (Hsp40) homolog, subfamily C, member 24 11 31369840-31431849 Predicted intracellular proteins Evidence at protein level HPA020025, HPA025237 Approved Approved Cytosol Expressed in all Expressed in all cerebral cortex,thyroid gland: 11.4 DNAJC3 HP58, P58, P58IPK, PRKRI ENSG00000102580 DnaJ (Hsp40) homolog, subfamily C, member 3 13 95677139-95794989 Disease related genes, Predicted secreted proteins Evidence at protein level HPA039336, HPA041326 Uncertain Approved Endoplasmic reticulum Endometrial cancer:3.47e-5 (favourable) Expressed in all Expressed in all thyroid gland: 88.1 DNAJC30 WBSCR18 ENSG00000176410 DnaJ (Hsp40) homolog, subfamily C, member 30 7 73680969-73683453 Predicted membrane proteins Evidence at protein level HPA017318 Uncertain Supported Renal cancer:4.91e-8 (favourable), Glioma:6.59e-5 (unfavourable) Expressed in all Expressed in all testis: 11.3 DNAJC4 HSPF2, MCG18 ENSG00000110011 DnaJ (Hsp40) homolog, subfamily C, member 4 11 64230278-64234286 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011947 Uncertain Colorectal cancer:3.12e-4 (unfavourable), Renal cancer:6.21e-4 (favourable) Expressed in all Expressed in all testis: 136.3 DNAJC5 CLN4, DNAJC5A, FLJ00118, FLJ13070 ENSG00000101152 DnaJ (Hsp40) homolog, subfamily C, member 5 20 63895182-63936031 Disease related genes, Predicted membrane proteins Evidence at protein level HPA012737, HPA013154 Approved Uncertain Golgi apparatus Renal cancer:7.70e-6 (favourable), Liver cancer:8.82e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 73.8 DNAJC7 TPR2, TTC2 ENSG00000168259 DnaJ (Hsp40) homolog, subfamily C, member 7 17 41976433-42021376 Predicted intracellular proteins Evidence at protein level HPA023015, HPA052395 Approved Supported Nucleoplasm
Cytosol Liver cancer:3.35e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.0 DNAJC8 SPF31 ENSG00000126698 DnaJ (Hsp40) homolog, subfamily C, member 8 1 28199456-28233025 Predicted intracellular proteins Evidence at protein level HPA026275, HPA026283 Approved Validated Nucleoplasm Endometrial cancer:6.95e-5 (favourable), Thyroid cancer:2.39e-4 (favourable), Liver cancer:4.71e-4 (unfavourable) Expressed in all Expressed in all lymph node: 94.7 DNAJC9 JDD1, SB73 ENSG00000213551 DnaJ (Hsp40) homolog, subfamily C, member 9 10 73183362-73248862 Predicted intracellular proteins Evidence at protein level HPA035215, HPA035216 Supported Supported Nucleoplasm
Plasma membrane Prostate cancer:7.07e-5 (unfavourable), Lung cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 37.4 DNAL1 1700010H15RiK, C14orf168, CILD16, MGC12435 ENSG00000119661 Dynein, axonemal, light chain 1 14 73644875-73703732 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053129 Uncertain Approved Nucleus
Microtubule organizing center Renal cancer:5.17e-8 (favourable) Expressed in all Expressed in all testis: 99.0 DNAL4 dJ327J16, PIG27 ENSG00000100246 Dynein, axonemal, light chain 4 22 38778508-38794198 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003647 Approved Approved Nucleus
Nucleoli
Centrosome
Cytosol Renal cancer:1.20e-6 (favourable) Expressed in all Expressed in all testis: 59.7 DNASE1L1 DNAS1L1, DNASEX, DNL1L, XIB ENSG00000013563 Deoxyribonuclease I-like 1 X 154401238-154412112 Predicted secreted proteins Evidence at protein level HPA072635 Approved Renal cancer:2.19e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 56.7 DNASE2 DNL, DNL2 ENSG00000105612 Deoxyribonuclease II, lysosomal 19 12875211-12881468 Enzymes, Predicted secreted proteins Evidence at protein level HPA066185 Supported Expressed in all Expressed in all thyroid gland: 58.9 DNLZ bA413M3.2, C9orf151, HEP, RP11-413M3.2, TIMM15, ZIM17 ENSG00000213221 DNL-type zinc finger 9 136359480-136363789 Predicted intracellular proteins Evidence at protein level HPA062738 Validated Nucleoplasm
Mitochondria Not detected Expressed in all cerebral cortex: 13.7 DNM1L DRP1, DVLP, DYMPLE, HDYNIV, VPS1 ENSG00000087470 Dynamin 1-like 12 32679200-32745650 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB009952, HPA039324 Supported Validated Vesicles
Cytosol Liver cancer:6.27e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 88.3 DNM2 CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII ENSG00000079805 Dynamin 2 19 10718079-10833488 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA054246 Supported Approved Golgi apparatus
Cytosol Liver cancer:3.63e-4 (unfavourable), Head and neck cancer:8.91e-4 (favourable) Expressed in all Expressed in all colon: 106.7 DNMBP ARHGEF36, KIAA1010, Tuba ENSG00000107554 Dynamin binding protein 10 99875577-100009919 Predicted intracellular proteins Evidence at protein level HPA037878, HPA058216 Uncertain Approved Nucleoli
Nuclear bodies
Golgi apparatus
Cytosol Endometrial cancer:4.95e-6 (favourable), Urothelial cancer:6.15e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.8 DNMT1 CXXC9, DNMT, MCMT ENSG00000130816 DNA (cytosine-5-)-methyltransferase 1 19 10133345-10231286 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002694, CAB005876 Supported Validated Nucleoplasm Liver cancer:1.46e-4 (unfavourable) Expressed in all Expressed in all placenta: 51.2 DNMT3A ENSG00000119772 DNA (cytosine-5-)-methyltransferase 3 alpha 2 25227855-25342590 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009469, HPA026588 Approved Supported Nucleoplasm Pancreatic cancer:1.18e-4 (favourable), Endometrial cancer:1.55e-4 (unfavourable), Liver cancer:1.58e-4 (unfavourable), Renal cancer:2.49e-4 (unfavourable) Expressed in all Expressed in all placenta: 22.6 DNPEP ASPEP, DAP ENSG00000123992 Aspartyl aminopeptidase 2 219373546-219400022 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036398, HPA044860 Supported Supported Cytosol Expressed in all Expressed in all testis: 65.8 DNPH1 C6orf108, dJ330M21.3, rcl ENSG00000112667 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 6 43225629-43229484 Predicted intracellular proteins Evidence at protein level HPA029675, HPA029676 Supported Approved Nucleoplasm
Cytosol Expressed in all Expressed in all duodenum: 107.2 DNTTIP1 C20orf167, dJ447F3.4, Tdif1 ENSG00000101457 Deoxynucleotidyltransferase, terminal, interacting protein 1 20 45791937-45811427 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042479, HPA045496 Validated Nucleus Renal cancer:1.90e-6 (unfavourable), Liver cancer:1.79e-5 (unfavourable) Expressed in all Expressed in all testis: 44.6 DOCK9 KIAA1058, ZIZ1 ENSG00000088387 Dedicator of cytokinesis 9 13 98793487-99086625 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034061, CAB034065, HPA043940 Uncertain Expressed in all Expressed in all placenta: 157.4 DOK4 FLJ10488 ENSG00000125170 Docking protein 4 16 57471922-57487327 Predicted intracellular proteins Evidence at protein level HPA055849 Supported Approved Vesicles
Microtubules
Cytokinetic bridge Expressed in all Expressed in all small intestine: 55.8 DOLPP1 LSFR2 ENSG00000167130 Dolichyldiphosphatase 1 9 129081100-129090438 Enzymes, Predicted membrane proteins Evidence at protein level HPA019179 Approved Approved Vesicles
Intermediate filaments Expressed in all Expressed in all duodenum: 26.5 DOPEY2 C21orf5, KIAA0933 ENSG00000142197 Dopey family member 2 21 36156782-36294274 Predicted intracellular proteins Evidence at protein level CAB034922, HPA072065 Approved Approved Nucleoplasm
Mitochondria Breast cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 83.9 DPCD DKFZP566F084, RP11-529I10.4 ENSG00000166171 Deleted in primary ciliary dyskinesia homolog (mouse) 10 101570560-101609668 Predicted intracellular proteins Evidence at protein level HPA036603, HPA036604 Supported Approved Nuclear speckles Endometrial cancer:6.57e-4 (favourable) Expressed in all Expressed in all testis: 152.7 DPF2 BAF45d, REQ, ubi-d4 ENSG00000133884 D4, zinc and double PHD fingers family 2 11 65333754-65353249 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020880, HPA056786 Approved Supported Nucleoplasm Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 51.4 DPH1 DPH2L, DPH2L1, OVCA1 ENSG00000108963 Diphthamide biosynthesis 1 17 2030110-2043430 Predicted intracellular proteins Evidence at protein level HPA069750 Approved Nucleoplasm
Cell Junctions Pancreatic cancer:1.78e-5 (favourable) Expressed in all Expressed in all fallopian tube: 30.8 DPH2 DPH2L2 ENSG00000132768 DPH2 homolog 1 43970000-43973369 Predicted intracellular proteins Evidence at protein level HPA045796 Uncertain Approved Nucleus Liver cancer:1.17e-8 (unfavourable), Stomach cancer:1.37e-4 (favourable) Expressed in all Expressed in all appendix: 14.7 DPH3 DELGIP, DELGIP1, DESR1, DPH3A, KTI11, MGC20197, ZCSL2 ENSG00000154813 Diphthamide biosynthesis 3 3 16257978-16264972 Predicted intracellular proteins Evidence at protein level HPA035287 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:2.24e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 22.9 DPH5 CGI-30 ENSG00000117543 Diphthamide biosynthesis 5 1 100989623-101026088 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046439, HPA076234 Approved Uncertain Golgi apparatus Expressed in all Expressed in all ovary: 51.9 DPH6 ATPBD4, MGC14798 ENSG00000134146 Diphthamine biosynthesis 6 15 35217345-35546193 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042976, HPA055496 Approved Validated Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 18.0 DPH7 C9orf112, FLJ90634, RRT2, WDR85 ENSG00000148399 Diphthamide biosynthesis 7 9 137554904-137578935 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022911 Uncertain Approved Nuclear bodies Renal cancer:1.52e-5 (unfavourable), Urothelial cancer:3.23e-4 (favourable), Pancreatic cancer:6.52e-4 (favourable) Expressed in all Expressed in all fallopian tube: 23.0 DPM1 CDGIE, MPDS ENSG00000000419 Dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 20 50934867-50958555 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051818 Approved Liver cancer:1.94e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 80.6 DPM3 MGC125904, MGC125905, MGC34275 ENSG00000179085 Dolichyl-phosphate mannosyltransferase polypeptide 3 1 155139891-155140595 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014667 Approved Endometrial cancer:7.09e-5 (favourable), Ovarian cancer:8.97e-5 (favourable), Urothelial cancer:8.64e-4 (favourable) Expressed in all Expressed in all adrenal gland: 78.8 DPP3 ENSG00000254986 Dipeptidyl-peptidase 3 11 66480013-66509657 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035780, HPA035781 Approved Validated Nuclear speckles
Plasma membrane
Cytosol Stomach cancer:1.34e-4 (favourable) Expressed in all Expressed in all colon: 30.0 DPP7 DPPII ENSG00000176978 Dipeptidyl-peptidase 7 9 137110542-137115177 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021282, CAB025541, HPA059381 Supported Validated Golgi apparatus
Vesicles Colorectal cancer:6.07e-6 (unfavourable), Pancreatic cancer:8.31e-5 (favourable) Expressed in all Expressed in all adrenal gland: 71.0 DPP8 DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141 ENSG00000074603 Dipeptidyl-peptidase 8 15 65442463-65517704 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008706 Approved Supported Cytosol Expressed in all Expressed in all testis: 47.9 DPP9 ENSG00000142002 Dipeptidyl-peptidase 9 19 4675224-4724673 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036059 Approved Supported Cytosol Renal cancer:3.38e-8 (unfavourable), Endometrial cancer:6.21e-5 (favourable), Stomach cancer:7.72e-5 (favourable), Breast cancer:4.96e-4 (favourable) Expressed in all Expressed in all appendix: 34.2 DPY19L1 KIAA0877 ENSG00000173852 Dpy-19-like 1 (C. elegans) 7 34928876-35038271 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059139 Uncertain Approved Vesicles Pancreatic cancer:2.99e-4 (unfavourable) Expressed in all Expressed in all testis: 69.2 DPY19L4 ENSG00000156162 Dpy-19-like 4 (C. elegans) 8 94719703-94793836 Predicted membrane proteins Evidence at protein level HPA024780 Approved Approved Vesicles Endometrial cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.2 DPY30 Cps25, HDPY-30, Saf19 ENSG00000162961 Dpy-30 histone methyltransferase complex regulatory subunit 2 31867809-32039812 Predicted intracellular proteins Evidence at protein level HPA043761 Supported Validated Nucleoplasm
Golgi apparatus Renal cancer:4.26e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 136.5 DPYD DPD ENSG00000188641 Dihydropyrimidine dehydrogenase 1 97077743-97921049 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033241, HPA045210 Uncertain Pancreatic cancer:6.27e-4 (unfavourable) Expressed in all Expressed in all lung: 44.1 DPYSL2 CRMP2, DHPRP2, DRP-2, DRP2 ENSG00000092964 Dihydropyrimidinase-like 2 8 26514275-26658178 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002381, CAB018719 Supported Supported Plasma membrane
Cytosol Urothelial cancer:5.41e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 381.2 DR1 NC2-BETA, NC2B ENSG00000117505 Down-regulator of transcription 1 1 93345888-93369498 Predicted intracellular proteins Evidence at protein level HPA050785, HPA055308 Supported Supported Nucleus Liver cancer:9.95e-7 (unfavourable), Colorectal cancer:4.79e-4 (favourable), Renal cancer:7.23e-4 (unfavourable), Pancreatic cancer:9.11e-4 (unfavourable) Expressed in all Expressed in all testis: 101.8 DRAM1 DRAM, FLJ11259 ENSG00000136048 DNA-damage regulated autophagy modulator 1 12 101877351-102012130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:6.52e-8 (favourable), Renal cancer:3.91e-4 (unfavourable) Expressed in all Expressed in all lung: 133.6 DRAP1 NC2-alpha ENSG00000175550 DR1-associated protein 1 (negative cofactor 2 alpha) 11 65919257-65921561 Predicted intracellular proteins Evidence at protein level HPA006790 Uncertain Approved Cytosol Renal cancer:3.73e-5 (unfavourable), Thyroid cancer:4.96e-5 (favourable) Expressed in all Expressed in all testis: 141.2 DRG1 NEDD3 ENSG00000185721 Developmentally regulated GTP binding protein 1 22 31399523-31528740 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001218 Approved Supported Nuclear bodies
Cytosol Liver cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all testis: 263.5 DRG2 ENSG00000108591 Developmentally regulated GTP binding protein 2 17 18087886-18107971 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007716 Approved Supported Nucleoplasm
Vesicles
Cytosol Endometrial cancer:1.56e-4 (favourable), Prostate cancer:7.34e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 29.0 DROSHA Etohi2, HSA242976, RN3, RNASE3L, RNASEN ENSG00000113360 Drosha, ribonuclease type III 5 31400497-31532196 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031150 Approved Nucleoplasm
Plasma membrane Liver cancer:1.39e-4 (unfavourable), Endometrial cancer:6.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.0 DSCR3 DCRA ENSG00000157538 Down syndrome critical region 3 21 37223420-37267919 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023288 Uncertain Approved Mitochondria Renal cancer:8.54e-4 (favourable) Expressed in all Expressed in all kidney: 32.0 DST BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2 ENSG00000151914 Dystonin 6 56457987-56954628 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030200 Uncertain Approved Nucleus
Microtubules
Cytosol Expressed in all Expressed in all skin: 192.5 DSTN ACTDP, ADF ENSG00000125868 Destrin (actin depolymerizing factor) 20 17569863-17609919 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037094 Approved Expressed in all Expressed in all seminal vesicle: 1044.5 DTD1 bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68 ENSG00000125821 D-tyrosyl-tRNA deacylase 1 20 18567453-18763917 Predicted intracellular proteins Evidence at protein level HPA040981, HPA042653 Uncertain Uncertain Nucleoli
Cytosol Expressed in all Expressed in all cerebral cortex: 55.9 DTNBP1 BLOC1S8, DBND, Dysbindin, HPS7, My031 ENSG00000047579 Dystrobrevin binding protein 1 6 15522801-15663058 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028053, HPA029615, HPA029616 Supported Supported Microtubules
Midbody Lung cancer:6.34e-5 (favourable), Cervical cancer:2.82e-4 (favourable), Liver cancer:8.72e-4 (unfavourable) Expressed in all Expressed in all lymph node: 33.2 DTWD1 MDS009, MGC111207 ENSG00000104047 DTW domain containing 1 15 49620980-49656232 Predicted intracellular proteins Evidence at protein level HPA042214 Uncertain Approved Nucleus
Nucleoli
Vesicles Expressed in all Expressed in all endometrium: 39.5 DTX2 KIAA1528, RNF58 ENSG00000091073 Deltex 2, E3 ubiquitin ligase 7 76461676-76505995 Predicted intracellular proteins Evidence at protein level HPA042931 Approved Supported Nucleoplasm
Nuclear membrane Renal cancer:1.13e-8 (unfavourable), Glioma:7.25e-4 (unfavourable) Expressed in all Expressed in all esophagus: 37.3 DTX3 FLJ34766, RNF154 ENSG00000178498 Deltex 3, E3 ubiquitin ligase 12 57604622-57609804 Predicted intracellular proteins Evidence at protein level HPA059654 Approved Approved Nucleus
Nucleoli
Golgi apparatus Pancreatic cancer:1.44e-4 (favourable), Lung cancer:9.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 103.1 DTX3L BBAP ENSG00000163840 Deltex 3 like, E3 ubiquitin ligase 3 122564238-122575203 Predicted intracellular proteins Evidence at protein level HPA010570 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:8.99e-4 (unfavourable) Expressed in all Expressed in all spleen: 36.7 DTYMK CDC8, TMPK, TYMK ENSG00000168393 Deoxythymidylate kinase (thymidylate kinase) 2 241675742-241686991 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042593, HPA042719 Approved Approved Mitochondria Liver cancer:1.73e-5 (unfavourable), Renal cancer:1.22e-4 (unfavourable) Expressed in all Expressed in all lymph node: 24.3 DUS1L DUS1, PP3111 ENSG00000169718 Dihydrouridine synthase 1-like 17 82057506-82065887 Predicted intracellular proteins Evidence at protein level HPA023384 Uncertain Approved Plasma membrane Renal cancer:5.89e-5 (unfavourable) Expressed in all Expressed in all skin: 99.1 DUS3L DUS3, FLJ13896 ENSG00000141994 Dihydrouridine synthase 3-like 19 5784832-5791238 Predicted intracellular proteins Evidence at protein level HPA041854, HPA041944, HPA062846 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 26.8 DUSP1 CL100, HVH1, MKP-1, PTPN10 ENSG00000120129 Dual specificity phosphatase 1 5 172768090-172771195 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB018554, HPA069577 Approved Approved Nucleoli
Cytosol Stomach cancer:3.11e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 1020.1 DUSP11 PIR1 ENSG00000144048 Dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2 73762184-73780157 Predicted intracellular proteins Evidence at protein level HPA021052 Supported Nucleus
Nucleoli fibrillar center
Cytokinetic bridge Liver cancer:2.10e-7 (unfavourable) Expressed in all Expressed in all fallopian tube: 61.9 DUSP12 DUSP1, YVH1 ENSG00000081721 Dual specificity phosphatase 12 1 161749758-161757238 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008840 Uncertain Supported Nucleus Renal cancer:1.55e-7 (unfavourable), Liver cancer:1.99e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 20.4 DUSP16 KIAA1700, MKP-7, MKP7 ENSG00000111266 Dual specificity phosphatase 16 12 12474210-12562383 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020326 Approved Supported Nucleoplasm Head and neck cancer:1.01e-4 (favourable) Expressed in all Expressed in all adrenal gland: 33.4 DUSP22 JKAP, JSP1, MKPX, VHX ENSG00000112679 Dual specificity phosphatase 22 6 291630-351355 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031394 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 85.1 DUSP23 DUSP25, FLJ20442 ENSG00000158716 Dual specificity phosphatase 23 1 159780932-159782543 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028211, HPA045792 Approved Supported Nucleoplasm Renal cancer:2.59e-5 (unfavourable), Liver cancer:3.06e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 40.6 DUSP3 VHR ENSG00000108861 Dual specificity phosphatase 3 17 43766121-43778988 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063616 Supported Nucleoplasm
Cytosol Renal cancer:5.49e-5 (favourable), Head and neck cancer:3.00e-4 (unfavourable), Glioma:9.23e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 99.6 DUSP6 MKP-3, PYST1 ENSG00000139318 Dual specificity phosphatase 6 12 89347232-89353271 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017566, HPA053188 Approved Uncertain Nucleoplasm
Cytosol Endometrial cancer:7.21e-4 (favourable) Expressed in all Expressed in all adipose tissue: 140.8 DUSP7 MKP-X, PYST2 ENSG00000164086 Dual specificity phosphatase 7 3 52048919-52056550 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:8.84e-6 (unfavourable) Expressed in all Expressed in all skin: 45.2 DUT dUTPase ENSG00000128951 Deoxyuridine triphosphatase 15 48331011-48343373 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054422, HPA060360 Supported Supported Nucleoplasm Expressed in all Expressed in all lymph node: 116.0 DVL1 ENSG00000107404 Dishevelled segment polarity protein 1 1 1335276-1349350 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011538 Approved Testis cancer:3.33e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 79.5 DVL2 ENSG00000004975 Dishevelled segment polarity protein 2 17 7225341-7234545 Predicted intracellular proteins Evidence at protein level CAB009312, HPA021611, HPA022914, HPA064732 Approved Validated Nucleoplasm
Nuclear bodies Liver cancer:4.34e-6 (unfavourable), Pancreatic cancer:3.85e-4 (favourable) Expressed in all Expressed in all ovary: 36.1 DVL3 KIAA0208 ENSG00000161202 Dishevelled segment polarity protein 3 3 184155388-184173610 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB046486, HPA058265 Approved Approved Intermediate filaments
Midbody ring
Centrosome Renal cancer:1.53e-8 (unfavourable), Prostate cancer:4.77e-5 (unfavourable), Colorectal cancer:1.90e-4 (unfavourable), Liver cancer:8.41e-4 (unfavourable) Expressed in all Expressed in all placenta: 55.0 DYM DMC, FLJ20071, SMC ENSG00000141627 Dymeclin 18 49041474-49461347 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043551, HPA049187 Approved Supported Golgi apparatus Renal cancer:2.76e-5 (favourable), Urothelial cancer:5.26e-5 (unfavourable) Expressed in all Expressed in all testis: 79.7 DYNC1H1 CMT2O, DHC1, DNCH1, Dnchc1, DNCL, DNECL, HL-3, p22 ENSG00000197102 Dynein, cytoplasmic 1, heavy chain 1 14 101964528-102050792 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003742, CAB010443 Supported Supported Centrosome
Cytosol Liver cancer:3.03e-7 (unfavourable), Renal cancer:1.09e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 80.8 DYNC1I2 DNCI2 ENSG00000077380 Dynein, cytoplasmic 1, intermediate chain 2 2 171687409-171748420 Predicted intracellular proteins Evidence at protein level CAB033836, HPA040619, HPA053987 Supported Supported Nucleoli
Endoplasmic reticulum
Microtubules
Cytosol Renal cancer:8.04e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 147.0 DYNC1LI1 DNCLI1 ENSG00000144635 Dynein, cytoplasmic 1, light intermediate chain 1 3 32525971-32570874 Predicted intracellular proteins Evidence at protein level HPA035013 Approved Supported Centrosome
Cytosol Liver cancer:9.19e-9 (unfavourable) Expressed in all Expressed in all testis: 74.0 DYNC1LI2 DNCLI2 ENSG00000135720 Dynein, cytoplasmic 1, light intermediate chain 2 16 66720893-66751798 Predicted intracellular proteins Evidence at protein level HPA057201 Approved Centrosome
Cytosol Expressed in all Expressed in all cerebral cortex: 141.9 DYNC2LI1 CGI-60, D2LIC, DKFZP564A033, LIC3 ENSG00000138036 Dynein, cytoplasmic 2, light intermediate chain 1 2 43774039-43810010 Predicted intracellular proteins Evidence at protein level HPA062905 Approved Approved Cytosol Renal cancer:2.73e-5 (favourable) Expressed in all Expressed in all fallopian tube: 85.4 DYNLL1 DLC1, DLC8, DNCL1, hdlc1, LC8, PIN ENSG00000088986 Dynein, light chain, LC8-type 1 12 120469850-120498493 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039954 Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:7.97e-7 (unfavourable), Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 769.1 DYNLL2 Dlc2, DNCL1B, MGC17810, RSPH22 ENSG00000264364 Dynein, light chain, LC8-type 2 17 58083415-58095536 Predicted intracellular proteins Evidence at protein level HPA039954 Uncertain Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.12e-12 (favourable), Pancreatic cancer:5.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 95.3 DYNLRB1 DNCL2A, DNLC2A, ROBLD1 ENSG00000125971 Dynein, light chain, roadblock-type 1 20 34516409-34540958 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009845 Approved Liver cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 341.9 DYNLT1 TCTEL1 ENSG00000146425 Dynein, light chain, Tctex-type 1 6 158636474-158644739 Predicted intracellular proteins Evidence at protein level HPA046559 Supported Nucleoplasm Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 270.2 DYNLT3 TCTE1L, TCTEX1L ENSG00000165169 Dynein, light chain, Tctex-type 3 X 37836757-37847637 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003938 Approved Glioma:4.22e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 77.5 DYRK1A DYRK, DYRK1, MNBH ENSG00000157540 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 21 37365790-37517450 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015323, HPA015810 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all parathyroid gland: 60.2 DYRK2 ENSG00000127334 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 12 67648338-67665406 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027230, HPA056902 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all small intestine: 31.7 DZIP3 hRUL138, PPP1R66 ENSG00000198919 DAZ interacting zinc finger protein 3 3 108589682-108694846 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035066, HPA049232 Approved Approved Vesicles Renal cancer:3.65e-4 (favourable) Expressed in all Expressed in all testis: 65.8 E2F4 E2F-4 ENSG00000205250 E2F transcription factor 4, p107/p130-binding 16 67192169-67198918 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054128 Supported Nucleoplasm Expressed in all Expressed in all placenta: 63.7 E4F1 E4F ENSG00000167967 E4F transcription factor 1 16 2223566-2235742 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052042, HPA071325 Validated Nucleoplasm Head and neck cancer:1.10e-4 (favourable), Renal cancer:5.50e-4 (unfavourable), Cervical cancer:9.13e-4 (favourable) Expressed in all Expressed in all skin,spleen: 12.8 EAF1 ENSG00000144597 ELL associated factor 1 3 15427355-15450635 Predicted intracellular proteins Evidence at protein level HPA059516, HPA060569, HPA069538 Supported Validated Nucleoplasm
Nuclear bodies
Vesicles Lung cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 33.7 EAPP BM036, C14orf11, FLJ20578 ENSG00000129518 E2F-associated phosphoprotein 14 34515929-34539711 Predicted intracellular proteins Evidence at protein level HPA002916 Approved Approved Nucleus
Golgi apparatus
Cytosol Renal cancer:2.23e-6 (favourable), Thyroid cancer:2.96e-4 (favourable), Lung cancer:9.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 74.6 EARS2 KIAA1970, MSE1 ENSG00000103356 Glutamyl-tRNA synthetase 2, mitochondrial 16 23522014-23557731 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043289, HPA043633 Approved Supported Nucleoplasm
Mitochondria Renal cancer:3.16e-6 (favourable), Pancreatic cancer:7.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 32.3 EBAG9 EB9, RCAS1 ENSG00000147654 Estrogen receptor binding site associated, antigen, 9 8 109539711-109565996 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021153, HPA021154, CAB072810, CAB072811, CAB072812 Supported Validated Golgi apparatus Expressed in all Expressed in all thyroid gland: 96.1 EBNA1BP2 EBP2, NOBP, P40 ENSG00000117395 EBNA1 binding protein 2 1 43164175-43270936 Predicted intracellular proteins Evidence at protein level HPA026512, HPA028277 Approved Validated Nucleoli Liver cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all testis: 71.7 EBP CDPX2, CHO2, CPX, CPXD ENSG00000147155 Emopamil binding protein (sterol isomerase) X 48521158-48528716 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA003130 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all liver: 91.1 EBPL EBRP ENSG00000123179 Emopamil binding protein-like 13 49660723-49691475 Predicted membrane proteins Evidence at protein level HPA049891 Approved Supported Endoplasmic reticulum Renal cancer:7.18e-8 (unfavourable), Ovarian cancer:1.38e-4 (unfavourable) Expressed in all Expressed in all liver: 61.3 ECD GCR2, hSGT1 ENSG00000122882 Ecdysoneless homolog (Drosophila) 10 73130155-73169055 Predicted intracellular proteins Evidence at protein level HPA006465 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.1 ECE1 ECE ENSG00000117298 Endothelin converting enzyme 1 1 21217247-21345504 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001490, HPA013616 Approved Expressed in all Expressed in all parathyroid gland: 428.4 ECH1 HPXEL ENSG00000104823 Enoyl CoA hydratase 1, peroxisomal 19 38815422-38832005 Predicted intracellular proteins Evidence at protein level HPA002907, HPA005835 Supported Approved Supported Mitochondria Stomach cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 188.2 ECHDC1 dJ351K20.2 ENSG00000093144 Ethylmalonyl-CoA decarboxylase 1 6 127288710-127343609 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035445 Uncertain Expressed in all Expressed in all adipose tissue: 98.7 ECHDC3 FLJ20909 ENSG00000134463 Enoyl CoA hydratase domain containing 3 10 11742366-11764070 Predicted intracellular proteins Evidence at protein level HPA038306 Supported Approved Nucleus
Nucleoli
Mitochondria Renal cancer:3.43e-4 (favourable), Urothelial cancer:3.91e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 76.3 ECHS1 SCEH ENSG00000127884 Enoyl CoA hydratase, short chain, 1, mitochondrial 10 133362480-133373689 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003783, HPA021995, HPA022476 Supported Validated Mitochondria Renal cancer:8.57e-5 (favourable) Expressed in all Expressed in all liver: 437.5 ECI1 DCI ENSG00000167969 Enoyl-CoA delta isomerase 1 16 2239395-2252300 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041746, HPA043227 Supported Renal cancer:8.99e-8 (favourable), Cervical cancer:3.04e-5 (favourable), Liver cancer:1.07e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 69.3 ECI2 ACBD2, DRS1, HCA88, PECI ENSG00000198721 Enoyl-CoA delta isomerase 2 6 4115689-4135597 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022130, HPA031626 Supported Validated Peroxisomes Renal cancer:2.04e-6 (favourable), Head and neck cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all kidney: 236.6 ECSIT SITPEC ENSG00000130159 ECSIT signalling integrator 19 11505916-11529174 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042979 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.48e-9 (favourable) Expressed in all Expressed in all heart muscle: 53.9 EDC3 FLJ21128, hYjeF_N2-15q23, LSM16, YJDC, YJEFN2 ENSG00000179151 Enhancer of mRNA decapping 3 15 74630558-74696292 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040650, HPA044206, HPA066137 Uncertain Supported Cytoplasmic bodies Liver cancer:7.80e-5 (unfavourable) Expressed in all Expressed in all testis: 65.8 EDC4 Ge-1, HEDLS, RCD-8 ENSG00000038358 Enhancer of mRNA decapping 4 16 67873023-67884503 Predicted intracellular proteins Evidence at protein level HPA041164, HPA043038 Supported Validated Nucleoplasm
Cytoplasmic bodies Liver cancer:7.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.0 EDEM1 EDEM, KIAA0212 ENSG00000134109 ER degradation enhancer, mannosidase alpha-like 1 3 5187646-5219957 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029565 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all lymph node: 48.3 EDEM2 bA4204.1, C20orf31, C20orf49, FLJ10783 ENSG00000088298 ER degradation enhancer, mannosidase alpha-like 2 20 35115357-35147364 Predicted secreted proteins Evidence at protein level CAB037238, HPA048353 Approved Renal cancer:4.76e-6 (unfavourable) Expressed in all Expressed in all epididymis: 53.8 EDEM3 C1orf22 ENSG00000116406 ER degradation enhancer, mannosidase alpha-like 3 1 184690231-184754913 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA025754, HPA025755, HPA027297 Approved Approved Endoplasmic reticulum Renal cancer:1.63e-6 (unfavourable) Expressed in all Expressed in all stomach: 34.4 EDF1 CFAP280, EDF-1 ENSG00000107223 Endothelial differentiation-related factor 1 9 136862119-136866286 Predicted intracellular proteins Evidence at protein level HPA035642 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all small intestine: 569.2 EDRF1 C10orf137, DKFZp586F1019, FLJ21617 ENSG00000107938 Erythroid differentiation regulatory factor 1 10 125719515-125764143 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031820 Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:3.16e-5 (unfavourable) Expressed in all Expressed in all testis: 27.5 EEA1 ZFYVE2 ENSG00000102189 Early endosome antigen 1 12 92770637-92929331 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005861, CAB018782, HPA038158, HPA038159 Supported Supported Vesicles Expressed in all Expressed in all parathyroid gland: 16.5 EED HEED, WAIT-1 ENSG00000074266 Embryonic ectoderm development 11 86244544-86278813 Predicted intracellular proteins Evidence at protein level CAB012211, HPA060089, HPA061140 Supported Supported Nucleoplasm Renal cancer:1.36e-7 (unfavourable), Liver cancer:1.80e-5 (unfavourable), Urothelial cancer:2.27e-5 (favourable) Expressed in all Expressed in all lymph node: 30.7 EEF1A1 EE1A1, EEF1A, EF1A, LENG7 ENSG00000156508 Eukaryotic translation elongation factor 1 alpha 1 6 73515750-73523797 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051759, HPA053862, HPA056990 Supported Supported Cytosol Liver cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all ovary: 14688.0 EEF1B2 ENSG00000114942 Eukaryotic translation elongation factor 1 beta 2 2 206159585-206162928 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012477, HPA035029 Supported Approved Nucleoli fibrillar center
Cytosol Renal cancer:3.62e-6 (unfavourable), Breast cancer:2.60e-4 (favourable), Melanoma:9.95e-4 (unfavourable) Expressed in all Expressed in all breast: 1028.1 EEF1D EF-1D, FLJ20897 ENSG00000104529 Eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 8 143579697-143599541 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045101, HPA051002 Supported Supported Nucleus
Nucleoli fibrillar center Renal cancer:2.58e-5 (unfavourable), Liver cancer:3.82e-4 (unfavourable) Expressed in all Expressed in all ovary: 607.1 EEF1E1 AIMP3, P18 ENSG00000124802 Eukaryotic translation elongation factor 1 epsilon 1 6 8073360-8102578 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027901, HPA057866 Approved Supported Nucleus
Cytosol Liver cancer:1.55e-7 (unfavourable), Cervical cancer:3.16e-4 (favourable), Ovarian cancer:3.24e-4 (favourable) Expressed in all Expressed in all testis: 101.7 EEF1G EF1G ENSG00000254772 Eukaryotic translation elongation factor 1 gamma 11 62559601-62574086 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040688 Approved Approved Mitochondria Mixed Expressed in all ovary: 2987.8 EEF2 EEF-2, EF2 ENSG00000167658 Eukaryotic translation elongation factor 2 19 3976056-3985469 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007795, HPA040534, HPA057351 Approved Validated Plasma membrane
Cytosol Endometrial cancer:1.81e-6 (favourable), Renal cancer:1.25e-5 (favourable) Expressed in all Expressed in all ovary: 1621.9 EEF2K eEF-2K ENSG00000103319 Eukaryotic elongation factor 2 kinase 16 22206282-22288732 Enzymes, Predicted intracellular proteins Evidence at protein level CAB007818, HPA056061 Approved Approved Nucleoplasm Renal cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all skin: 57.5 EEFSEC EFSEC, SELB ENSG00000132394 Eukaryotic elongation factor, selenocysteine-tRNA-specific 3 128153454-128408646 Predicted intracellular proteins Evidence at protein level HPA035795 Approved Approved Nucleus
Nuclear bodies
Cytosol Cervical cancer:2.98e-5 (favourable) Expressed in all Expressed in all testis: 18.8 EEPD1 KIAA1706 ENSG00000122547 Endonuclease/exonuclease/phosphatase family domain containing 1 7 36153149-36301543 Predicted intracellular proteins Evidence at protein level HPA053668 Approved Nuclear speckles
Vesicles
Plasma membrane Expressed in all Expressed in all cerebral cortex: 27.2 EFCAB14 KIAA0494 ENSG00000159658 EF-hand calcium binding domain 14 1 46675159-46719064 Predicted membrane proteins Evidence at protein level HPA011224, HPA011938 Supported Approved Nucleoli
Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 299.7 EFCAB2 CFAP200, DRC8, MGC12458 ENSG00000203666 EF-hand calcium binding domain 2 1 244969705-245127164 Predicted intracellular proteins Evidence at protein level HPA031206, HPA031207 Approved Approved Plasma membrane
Cytosol Thyroid cancer:6.51e-4 (unfavourable) Mixed Expressed in all fallopian tube: 57.4 EFEMP2 FBLN4, UPH1 ENSG00000172638 EGF containing fibulin-like extracellular matrix protein 2 11 65866441-65873592 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023270 Approved Renal cancer:3.94e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 49.9 EFHD2 MGC4342 ENSG00000142634 EF-hand domain family, member D2 1 15409895-15430343 Predicted intracellular proteins Evidence at protein level HPA048961 Supported Approved Cytosol Renal cancer:6.31e-9 (unfavourable), Urothelial cancer:3.60e-5 (favourable), Thyroid cancer:2.70e-4 (favourable), Lung cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 113.3 EFR3A KIAA0143 ENSG00000132294 EFR3 homolog A 8 131904088-132013642 Predicted intracellular proteins Evidence at protein level HPA022859, HPA023092, HPA023402 Supported Supported Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 67.5 EFTUD1 FAM42A, FLJ13119, HsT19294, RIA1 ENSG00000140598 Elongation factor Tu GTP binding domain containing 1 15 82130230-82262763 Predicted intracellular proteins Evidence at protein level HPA039654, HPA047110, HPA052345 Uncertain Approved Cytosol Renal cancer:1.50e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 23.1 EFTUD2 SNRNP116, Snrp116, Snu114, U5-116KD ENSG00000108883 Elongation factor Tu GTP binding domain containing 2 17 44849943-44899662 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022021 Supported Supported Nucleoplasm
Cytosol Liver cancer:2.71e-6 (unfavourable) Expressed in all Expressed in all testis: 47.5 EGFL7 ZNEU1 ENSG00000172889 EGF-like-domain, multiple 7 9 136658856-136672678 Predicted secreted proteins Evidence at protein level CAB020815 Approved Colorectal cancer:4.22e-6 (unfavourable), Renal cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all placenta: 262.5 EGLN1 C1orf12, HIFPH2, PHD2, SM-20, ZMYND6 ENSG00000135766 Egl-9 family hypoxia-inducible factor 1 1 231363751-231425044 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022129 Approved Approved Cytosol Cervical cancer:2.99e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.5 EGLN2 HIFPH1, PHD1 ENSG00000269858 Egl-9 family hypoxia-inducible factor 2 19 40798996-40808433 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056649 Supported Nucleoplasm Cervical cancer:2.88e-4 (favourable), Pancreatic cancer:4.81e-4 (favourable) Expressed in all Expressed in all testis: 205.0 EGR1 AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 ENSG00000120738 Early growth response 1 5 138465490-138469315 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019427, HPA029937, HPA029938 Supported Validated Nucleoplasm Expressed in all Expressed in all ovary: 1184.1 EHBP1 KIAA0903, NACSIN ENSG00000115504 EH domain binding protein 1 2 62673851-63046487 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035468, HPA035469 Supported Supported Plasma membrane
Cytosol Urothelial cancer:1.95e-8 (unfavourable), Lung cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all testis: 67.5 EHD1 FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1 ENSG00000110047 EH-domain containing 1 11 64851642-64888296 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049890, HPA049986, HPA066751, HPA067747 Approved Supported Plasma membrane Liver cancer:2.81e-5 (unfavourable) Expressed in all Expressed in all testis: 153.1 EHD4 PAST4 ENSG00000103966 EH-domain containing 4 15 41895939-41972578 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049890, HPA049986, HPA052729, HPA066751 Approved Approved Plasma membrane Expressed in all Expressed in all gallbladder: 37.2 EHMT1 bA188C12.1, Eu-HMTase1, FLJ12879, KIAA1876, KMT1D ENSG00000181090 Euchromatic histone-lysine N-methyltransferase 1 9 137618963-137870016 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA060022 Supported Nucleoplasm
Nuclear bodies Endometrial cancer:6.56e-4 (favourable), Head and neck cancer:8.91e-4 (favourable) Expressed in all Expressed in all testis: 75.6 EID1 C15orf3, CRI1, EID-1 ENSG00000255302 EP300 interacting inhibitor of differentiation 1 15 48877886-48880183 Predicted intracellular proteins Evidence at protein level HPA051122, HPA051123 Approved Supported Nucleoplasm Stomach cancer:2.91e-4 (unfavourable), Head and neck cancer:9.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 314.2 EID2 CRI2, EID-2, MGC20452 ENSG00000176396 EP300 interacting inhibitor of differentiation 2 19 39538250-39540230 Predicted intracellular proteins Evidence at protein level HPA045477 Uncertain Supported Nucleoplasm Prostate cancer:8.74e-4 (unfavourable), Colorectal cancer:9.73e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 21.4 EIF1 A121, EIF-1, EIF1A, ISO1, SUI1 ENSG00000173812 Eukaryotic translation initiation factor 1 17 41688885-41692668 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 482.5 EIF1AD haponin, MGC11102 ENSG00000175376 Eukaryotic translation initiation factor 1A domain containing 11 65996545-66002176 Predicted intracellular proteins Evidence at protein level HPA054991, HPA058735 Uncertain Supported Nucleoplasm
Vesicles Endometrial cancer:3.59e-5 (unfavourable), Liver cancer:8.63e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.3 EIF1AX eIF-1A, eIF-4C, EIF1A, EIF4C ENSG00000173674 Eukaryotic translation initiation factor 1A, X-linked X 20124518-20141844 Predicted intracellular proteins Evidence at protein level HPA002561 Uncertain Approved Approved Cytosol Expressed in all Expressed in all endometrium: 95.8 EIF1B GC20 ENSG00000114784 Eukaryotic translation initiation factor 1B 3 40309684-40312424 Predicted intracellular proteins Evidence at protein level Renal cancer:1.08e-5 (favourable), Liver cancer:1.94e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 229.2 EIF2A EIF-2A ENSG00000144895 Eukaryotic translation initiation factor 2A, 65kDa 3 150546678-150584242 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036256 Approved Approved Mitochondria
Cytosol Pancreatic cancer:6.57e-6 (unfavourable), Liver cancer:2.36e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 141.7 EIF2AK1 HRI, KIAA1369 ENSG00000086232 Eukaryotic translation initiation factor 2-alpha kinase 1 7 6022244-6059230 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016496, CAB022082, HPA061675 Approved Supported Nucleus
Cytosol Liver cancer:6.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 130.0 EIF2AK2 EIF2AK1, PKR, PPP1R83, PRKR ENSG00000055332 Eukaryotic translation initiation factor 2-alpha kinase 2 2 37099210-37157065 Enzymes, Predicted intracellular proteins Evidence at protein level CAB003845, HPA019795, HPA063893 Approved Validated Cytosol Pancreatic cancer:2.08e-4 (unfavourable), Endometrial cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.1 EIF2AK4 GCN2, KIAA1338 ENSG00000128829 Eukaryotic translation initiation factor 2 alpha kinase 4 15 39934146-40035591 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA011811 Approved Approved Cytosol Expressed in all Expressed in all endometrium: 61.5 EIF2B1 EIF-2B, EIF-2Balpha, EIF2B, EIF2BA ENSG00000111361 Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 12 123620406-123633766 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB034258, HPA049509 Approved Supported Cytosol Renal cancer:1.78e-9 (unfavourable), Liver cancer:6.75e-7 (unfavourable) Expressed in all Expressed in all skin: 59.4 EIF2B3 EIF-2B, EIF2Bgamma ENSG00000070785 Eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1 44850522-44986722 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024213, HPA024218, HPA024219 Supported Supported Vesicles
Cytosol Liver cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.6 EIF2B4 DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta ENSG00000115211 Eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 2 27364352-27370486 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB032234, HPA039993 Uncertain Approved Nuclear membrane
Actin filaments Renal cancer:5.46e-8 (unfavourable), Liver cancer:1.83e-4 (unfavourable) Expressed in all Expressed in all testis: 51.8 EIF2B5 EIF-2B, EIF2Bepsilon ENSG00000145191 Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 3 184135038-184684758 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015412, HPA064370, HPA069303 Uncertain Validated Cytosol Liver cancer:3.38e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 38.0 EIF2D LGTN ENSG00000143486 Eukaryotic translation initiation factor 2D 1 206571292-206612463 Predicted intracellular proteins Evidence at protein level HPA028220 Approved Approved Nuclear bodies
Cytosol Renal cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all ovary: 73.9 EIF2S1 EIF-2alpha, EIF2, EIF2A ENSG00000134001 Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 14 67359997-67386516 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011663, HPA064885 Supported Validated Nucleoplasm
Cytosol Liver cancer:4.73e-7 (unfavourable), Pancreatic cancer:4.97e-4 (unfavourable), Urothelial cancer:7.11e-4 (unfavourable) Expressed in all Expressed in all testis: 60.8 EIF2S2 EIF2, EIF2beta, PPP1R67 ENSG00000125977 Eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 20 34088298-34112332 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034415, HPA041262, HPA041332 Approved Supported Nucleoli
Endoplasmic reticulum Renal cancer:9.64e-10 (unfavourable), Liver cancer:3.23e-5 (unfavourable), Endometrial cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all placenta: 74.0 EIF2S3 EIF2, EIF2G, EIF2gamma ENSG00000130741 Eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa X 24054716-24077971 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012471 Approved Renal cancer:5.44e-6 (unfavourable), Liver cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all ovary: 179.1 EIF3A EIF3, eIF3-p170, eIF3-theta, eIF3a, EIF3S10, KIAA0139, TIF32 ENSG00000107581 Eukaryotic translation initiation factor 3, subunit A 10 119033670-119080823 Predicted intracellular proteins Evidence at protein level HPA038315, HPA038316 Supported Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 134.6 EIF3B eIF3b, EIF3S9, PRT1 ENSG00000106263 Eukaryotic translation initiation factor 3, subunit B 7 2354086-2380745 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017562, HPA048983 Approved Approved Nucleoplasm
Cytosol Liver cancer:4.41e-9 (unfavourable), Renal cancer:9.66e-6 (unfavourable), Head and neck cancer:2.20e-4 (unfavourable) Expressed in all Expressed in all testis: 102.9 EIF3C eIF3-p110, eIF3c, EIF3S8 ENSG00000184110 Eukaryotic translation initiation factor 3, subunit C 16 28688558-28735730 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034045, HPA047097, HPA049495, HPA050112 Supported Supported Cytosol Expressed in all Expressed in all parathyroid gland: 565.2 EIF3D eIF3-p66, eIF3-zeta, eIF3d, EIF3S7 ENSG00000100353 Eukaryotic translation initiation factor 3, subunit D 22 36510850-36529436 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045882, HPA063330, HPA066216 Approved Supported Cytosol Liver cancer:8.10e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 253.4 EIF3E eIF3-p48, eIF3e, EIF3S6, INT6 ENSG00000104408 Eukaryotic translation initiation factor 3, subunit E 8 108201216-108435333 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA023973 Approved Validated Nuclear bodies
Cytosol Renal cancer:3.06e-7 (unfavourable) Expressed in all Expressed in all ovary: 729.0 EIF3F eIF3-epsilon, eIF3-p47, eIF3f, EIF3S5 ENSG00000175390 Eukaryotic translation initiation factor 3, subunit F 11 7970251-8001862 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049250 Approved Approved Nucleoli
Cytosol Liver cancer:6.86e-4 (unfavourable) Expressed in all Expressed in all ovary: 177.4 EIF3G eIF3-delta, eIF3-p44, eIF3g, EIF3S4 ENSG00000130811 Eukaryotic translation initiation factor 3, subunit G 19 10115017-10119918 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041997 Approved Validated Cytosol Ovarian cancer:3.94e-4 (favourable) Expressed in all Expressed in all ovary: 217.5 EIF3H eIF3-gamma, eIF3-p40, eIF3h, EIF3S3 ENSG00000147677 Eukaryotic translation initiation factor 3, subunit H 8 116642130-116766925 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA023117, HPA023553 Approved Approved Cytosol Breast cancer:5.26e-4 (unfavourable), Cervical cancer:8.07e-4 (unfavourable), Liver cancer:8.34e-4 (unfavourable) Expressed in all Expressed in all ovary: 479.7 EIF3I eIF3-beta, eIF3-p36, eIF3i, EIF3S2, TRIP-1 ENSG00000084623 Eukaryotic translation initiation factor 3, subunit I 1 32221928-32231604 Predicted intracellular proteins Evidence at protein level HPA029939, HPA029940 Supported Uncertain Nucleoplasm
Cytosol Renal cancer:4.81e-6 (unfavourable), Endometrial cancer:2.14e-4 (favourable), Liver cancer:4.21e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 197.3 EIF3J eIF3-alpha, eIF3-p35, eIF3j, EIF3S1 ENSG00000104131 Eukaryotic translation initiation factor 3, subunit J 15 44537057-44563029 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050977 Approved Validated Cytosol Urothelial cancer:4.96e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 69.3 EIF3K ARG134, eIF3k, EIF3S12, HSPC029, M9, PLAC-24, PRO1474, PTD001 ENSG00000178982 Eukaryotic translation initiation factor 3, subunit K 19 38619082-38636955 Predicted intracellular proteins Evidence at protein level HPA045446, HPA054590 Uncertain Supported Cytosol Cervical cancer:1.31e-4 (favourable), Renal cancer:5.43e-4 (favourable) Expressed in all Expressed in all fallopian tube: 162.8 EIF3L EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025 ENSG00000100129 Eukaryotic translation initiation factor 3, subunit L 22 37848868-37889407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003028 Approved Approved Nucleus
Nucleoli Renal cancer:6.11e-4 (favourable) Expressed in all Expressed in all breast: 179.6 EIF3M eIF3m, FLJ29030, GA17, hfl-B5, PCID1, TANGO7 ENSG00000149100 Eukaryotic translation initiation factor 3, subunit M 11 32583798-32606262 Predicted intracellular proteins Evidence at protein level HPA031063 Approved Supported Cytosol Liver cancer:1.28e-9 (unfavourable) Expressed in all Expressed in all fallopian tube: 232.5 EIF4A1 DDX2A, EIF-4A, EIF4A ENSG00000161960 Eukaryotic translation initiation factor 4A1 17 7572706-7579005 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011689, HPA068286 Uncertain Approved Cytosol Renal cancer:1.76e-8 (unfavourable) Expressed in all Expressed in all smooth muscle: 452.3 EIF4A2 BM-010, DDX2B, EIF4A, EIF4F ENSG00000156976 Eukaryotic translation initiation factor 4A2 3 186783205-186789900 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011690, HPA068286 Uncertain Approved Cytosol Expressed in all Expressed in all ovary: 724.4 EIF4A3 DDX48, EIF4AIII, KIAA0111 ENSG00000141543 Eukaryotic translation initiation factor 4A3 17 80135214-80147183 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA021878 Supported Supported Nucleoplasm Liver cancer:1.68e-5 (unfavourable), Colorectal cancer:3.57e-5 (favourable), Lung cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 112.3 EIF4B ENSG00000063046 Eukaryotic translation initiation factor 4B 12 53006158-53042209 Predicted intracellular proteins Evidence at protein level HPA039072, HPA046164 Approved Validated Cytosol Expressed in all Expressed in all ovary: 756.6 EIF4E EIF4E1, EIF4EL1, EIF4F ENSG00000151247 Eukaryotic translation initiation factor 4E 4 98871684-98930637 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004077, CAB016316, HPA051311 Supported Validated Cytosol
Cytoplasmic bodies Expressed in all Expressed in all testis: 103.0 EIF4E2 4EHP, EIF4EL3, IF4e ENSG00000135930 Eukaryotic translation initiation factor 4E family member 2 2 232550052-232583644 Predicted intracellular proteins Evidence at protein level HPA019253 Approved Mitochondria
Cytosol Liver cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all rectum: 76.7 EIF4E3 MGC39820 ENSG00000163412 Eukaryotic translation initiation factor 4E family member 3 3 71675416-71754773 Predicted intracellular proteins Evidence at protein level HPA058649 Approved Nucleoli fibrillar center Ovarian cancer:4.64e-5 (favourable), Renal cancer:6.99e-5 (favourable), Lung cancer:6.63e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 54.8 EIF4EBP1 4E-BP1, PHAS-I ENSG00000187840 Eukaryotic translation initiation factor 4E binding protein 1 8 38030341-38060365 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB005032, CAB005039, HPA023501 Supported Supported Nucleoplasm
Cytosol Renal cancer:0.00e+0 (unfavourable), Endometrial cancer:8.86e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 30.4 EIF4EBP2 ENSG00000148730 Eukaryotic translation initiation factor 4E binding protein 2 10 70404379-70428618 Predicted intracellular proteins Evidence at protein level CAB019415, HPA037410, HPA061665 Approved Approved Nucleoplasm
Mitochondria Renal cancer:6.69e-6 (favourable) Expressed in all Expressed in all adipose tissue: 74.1 EIF4EBP3 4E-BP3 ENSG00000243056 Eukaryotic translation initiation factor 4E binding protein 3 5 140547666-140549578 Predicted intracellular proteins Evidence at protein level HPA045537 Uncertain Renal cancer:3.10e-4 (favourable) Expressed in all Expressed in all fallopian tube: 59.5 EIF4ENIF1 2610509L04Rik, 4E-T, Clast4, FLJ21601 ENSG00000184708 Eukaryotic translation initiation factor 4E nuclear import factor 1 22 31436977-31496108 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001619, HPA002078 Supported Validated Vesicles Renal cancer:1.57e-4 (favourable) Expressed in all Expressed in all testis: 64.8 EIF4G1 EIF4F, EIF4G, p220, PARK18 ENSG00000114867 Eukaryotic translation initiation factor 4 gamma, 1 3 184314495-184335358 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB014774, HPA028487, HPA043866 Approved Validated Cytosol Liver cancer:7.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 206.5 EIF4G2 DAP5, NAT1, p97 ENSG00000110321 Eukaryotic translation initiation factor 4 gamma, 2 11 10797050-10809110 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005163, HPA006773, HPA016965 Approved Validated Cytosol Liver cancer:6.18e-5 (unfavourable), Renal cancer:1.67e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 638.5 EIF4G3 eIF4GII ENSG00000075151 Eukaryotic translation initiation factor 4 gamma, 3 1 20806292-21176888 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025031, HPA025039, HPA025041 Supported Approved Cytosol Liver cancer:9.60e-7 (unfavourable) Expressed in all Expressed in all testis: 169.5 EIF4H KIAA0038, WBSCR1, WSCR1 ENSG00000106682 Eukaryotic translation initiation factor 4H 7 74174245-74197101 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030542 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Head and neck cancer:2.15e-4 (unfavourable), Glioma:5.65e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 249.7 EIF5 ENSG00000100664 Eukaryotic translation initiation factor 5 14 103333544-103345025 Predicted intracellular proteins Evidence at protein level HPA000867, CAB004226 Supported Supported Plasma membrane
Cytosol Renal cancer:5.67e-7 (favourable) Expressed in all Expressed in all testis: 173.0 EIF5A EIF-5A, EIF5A1, MGC104255, MGC99547 ENSG00000132507 Eukaryotic translation initiation factor 5A 17 7306999-7312463 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB005042, HPA061298 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.63e-5 (unfavourable), Lung cancer:9.04e-4 (unfavourable) Expressed in all Expressed in all esophagus: 437.6 EIF5B DKFZp434I036, FLJ10524, IF2, KIAA0741 ENSG00000158417 Eukaryotic translation initiation factor 5B 2 99337353-99401326 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034648, HPA040095 Approved Approved Plasma membrane
Cytosol Liver cancer:7.15e-10 (unfavourable), Renal cancer:1.42e-6 (unfavourable), Ovarian cancer:8.99e-4 (favourable) Expressed in all Expressed in all testis: 67.2 EIF6 b(2)gcn, EIF3A, ITGB4BP, p27BBP ENSG00000242372 Eukaryotic translation initiation factor 6 20 35278907-35284985 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040873 Supported Supported Nucleoplasm Liver cancer:7.25e-5 (unfavourable) Expressed in all Expressed in all esophagus: 173.9 ELAC1 D29 ENSG00000141642 ElaC ribonuclease Z 1 18 50967991-50988121 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040867, HPA066483 Approved Supported Nucleus
Cytosol Renal cancer:8.43e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 17.9 ELAC2 FLJ10530, HPC2 ENSG00000006744 ElaC ribonuclease Z 2 17 12992391-13018187 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA019535 Approved Validated Nucleoplasm Endometrial cancer:3.24e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 53.9 ELAVL1 Hua, HUR, MelG ENSG00000066044 ELAV like RNA binding protein 1 19 7958579-8445041 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005256, HPA046298 Approved Supported Nucleus
Nucleoli
Cytosol Ovarian cancer:4.93e-4 (favourable) Expressed in all Expressed in all testis: 82.2 ELF1 ENSG00000120690 E74-like factor 1 (ets domain transcription factor) 13 40931920-41061440 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001755, CAB005172 Approved Supported Nucleoplasm Expressed in all Expressed in all bone marrow: 133.1 ELF2 EU32, NERF, NERF-1A, NERF-1B, NERF-2 ENSG00000109381 E74-like factor 2 (ets domain transcription factor) 4 139028112-139177218 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006057, HPA071166 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all testis: 69.0 ELK1 ENSG00000126767 ELK1, member of ETS oncogene family X 47635521-47650604 Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB003808, HPA036084, HPA064381 Supported Validated Nucleoplasm Renal cancer:3.25e-5 (unfavourable) Expressed in all Expressed in all ovary: 50.8 ELK3 ERP, NET, SAP2 ENSG00000111145 ELK3, ETS-domain protein (SRF accessory protein 2) 12 96194382-96269835 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001600 Approved Supported Nucleoplasm
Mitochondria Ovarian cancer:4.93e-4 (unfavourable) Expressed in all Expressed in all spleen: 58.6 ELK4 SAP1 ENSG00000158711 ELK4, ETS-domain protein (SRF accessory protein 1) 1 205597556-205631962 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028863 Uncertain Supported Nucleoplasm Renal cancer:2.94e-6 (unfavourable), Head and neck cancer:4.65e-4 (favourable) Expressed in all Expressed in all prostate: 41.5 ELL C19orf17, ELL1, Men, PPP1R68 ENSG00000105656 Elongation factor RNA polymerase II 19 18442663-18522127 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046076 Uncertain Expressed in all Expressed in all testis: 25.3 ELL2 ENSG00000118985 Elongation factor, RNA polymerase II, 2 5 95885098-95962071 Predicted intracellular proteins Evidence at protein level HPA013569 Supported Nucleoplasm Renal cancer:1.31e-4 (unfavourable), Stomach cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all skin: 69.0 ELMO1 CED-12, CED12, ELMO-1, KIAA0281 ENSG00000155849 Engulfment and cell motility 1 7 36854361-37449249 Predicted intracellular proteins Evidence at protein level Renal cancer:3.27e-5 (unfavourable), Pancreatic cancer:4.62e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 137.2 ELMO2 CED-12, CED12, ELMO-2, FLJ11656, KIAA1834 ENSG00000062598 Engulfment and cell motility 2 20 46366049-46432985 Predicted intracellular proteins Evidence at protein level HPA018811 Approved Supported Cytosol Liver cancer:4.08e-5 (unfavourable), Pancreatic cancer:6.10e-4 (favourable), Endometrial cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 58.4 ELMOD2 MGC10084 ENSG00000179387 ELMO/CED-12 domain containing 2 4 140524158-140553770 Predicted intracellular proteins Evidence at protein level HPA047600 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:1.17e-8 (favourable), Thyroid cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.0 ELMOD3 DFNB88, FLJ21977, RBED1, RBM29 ENSG00000115459 ELMO/CED-12 domain containing 3 2 85354394-85391752 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA012126 Approved Approved Nucleoplasm
Mitochondria Renal cancer:1.09e-6 (unfavourable), Pancreatic cancer:6.16e-6 (favourable), Urothelial cancer:2.85e-5 (favourable) Expressed in all Expressed in all adipose tissue: 11.1 ELMSAN1 C14orf117, C14orf43, LSR68 ENSG00000156030 ELM2 and Myb/SANT-like domain containing 1 14 73715122-73790285 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003111 Approved Validated Nucleoplasm Ovarian cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.8 ELOF1 ELF1, MGC4549 ENSG00000130165 ELF1 homolog, elongation factor 1 19 11551147-11559236 Predicted intracellular proteins Evidence at protein level HPA045606 Uncertain Approved Cytosol Cervical cancer:1.83e-4 (favourable) Expressed in all Expressed in all testis: 164.8 ELOVL1 Ssc1 ENSG00000066322 ELOVL fatty acid elongase 1 1 43363397-43368074 Enzymes, Predicted membrane proteins Evidence at protein level CAB033426, HPA056557 Approved Approved Endoplasmic reticulum Liver cancer:2.79e-7 (unfavourable), Cervical cancer:3.63e-5 (unfavourable), Pancreatic cancer:8.51e-4 (unfavourable) Expressed in all Expressed in all skin: 157.0 ELOVL5 dJ483K16.1, HELO1, SCA38 ENSG00000012660 ELOVL fatty acid elongase 5 6 53267398-53349179 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017042, HPA047752, HPA054197 Supported Validated Endoplasmic reticulum Renal cancer:1.94e-6 (unfavourable), Thyroid cancer:6.80e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 256.1 ELP2 FLJ10879, STATIP1, StIP ENSG00000134759 Elongator acetyltransferase complex subunit 2 18 36129444-36180556 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002996, CAB020835 Approved Validated Nucleus
Cytosol Colorectal cancer:5.41e-4 (favourable) Expressed in all Expressed in all ovary: 59.6 ELP3 FLJ10422, KAT9 ENSG00000134014 Elongator acetyltransferase complex subunit 3 8 28089673-28191156 Enzymes, Predicted intracellular proteins Evidence at protein level HPA025812 Uncertain Renal cancer:1.31e-5 (favourable), Colorectal cancer:9.25e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 37.6 ELP4 C11orf19, PAXNEB ENSG00000109911 Elongator acetyltransferase complex subunit 4 11 31509750-31783998 Predicted intracellular proteins Evidence at protein level HPA038572, HPA038573 Approved Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 20.1 ELP5 C17orf81, DERP6 ENSG00000170291 Elongator acetyltransferase complex subunit 5 17 7251416-7259940 Predicted intracellular proteins Evidence at protein level HPA023279 Uncertain Supported Cytosol Pancreatic cancer:2.62e-4 (favourable) Expressed in all Expressed in all testis: 172.8 ELP6 C3orf75, FLJ20211, TMEM103 ENSG00000163832 Elongator acetyltransferase complex subunit 6 3 47495640-47513761 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046358, HPA064545 Uncertain Approved Nucleus
Centrosome
Cytosol Renal cancer:3.42e-6 (favourable) Expressed in all Expressed in all testis: 32.0 EMC1 KIAA0090 ENSG00000127463 ER membrane protein complex subunit 1 1 19215664-19251552 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA048904 Approved Approved Microtubules
Cytokinetic bridge Liver cancer:8.56e-6 (unfavourable), Urothelial cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all placenta: 34.3 EMC10 C19orf63, HSM1, HSS1, INM02 ENSG00000161671 ER membrane protein complex subunit 10 19 50476400-50490870 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA053905 Uncertain Renal cancer:6.64e-6 (favourable), Pancreatic cancer:4.39e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 63.9 EMC2 KIAA0103, TTC35 ENSG00000104412 ER membrane protein complex subunit 2 8 108443601-108486918 Predicted intracellular proteins Evidence at protein level HPA022838 Approved Breast cancer:2.64e-4 (unfavourable) Expressed in all Expressed in all testis: 109.5 EMC3 TMEM111 ENSG00000125037 ER membrane protein complex subunit 3 3 9962537-10011116 Predicted membrane proteins Evidence at protein level HPA042372 Approved Approved Microtubules
Cytosol Renal cancer:2.81e-6 (favourable) Expressed in all Expressed in all testis: 90.7 EMC4 FLJ90746, MGC24415, PIG17, TMEM85 ENSG00000128463 ER membrane protein complex subunit 4 15 34224999-34230156 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026868, HPA053440 Approved Approved Cell Junctions
Focal adhesion sites Expressed in all Expressed in all epididymis: 120.7 EMC6 MGC2963, TMEM93 ENSG00000127774 ER membrane protein complex subunit 6 17 3668815-3669668 Predicted membrane proteins Evidence at protein level HPA062681 Uncertain Approved Nucleus
Centrosome Lung cancer:9.39e-5 (unfavourable), Cervical cancer:7.73e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 49.2 EMC7 C11orf3, C15orf24 ENSG00000134153 ER membrane protein complex subunit 7 15 34084017-34101948 Predicted membrane proteins Evidence at protein level HPA010029, HPA047572 Approved Approved Nucleoplasm Endometrial cancer:4.68e-5 (favourable), Head and neck cancer:9.25e-5 (unfavourable) Expressed in all Expressed in all testis: 129.1 EMC8 C16orf2, C16orf4, COX4NB, FAM158B, NOC4 ENSG00000131148 ER membrane protein complex subunit 8 16 85771758-85799608 Predicted intracellular proteins Evidence at protein level HPA049476 Approved Supported Cytosol Renal cancer:6.39e-4 (favourable), Liver cancer:8.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 17.1 EMC9 C14orf122, CGI-112, FAM158A ENSG00000100908 ER membrane protein complex subunit 9 14 24138959-24141588 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054715 Approved Golgi apparatus Ovarian cancer:2.43e-4 (favourable) Expressed in all Expressed in all adrenal gland: 21.4 EMD LEMD5, STA ENSG00000102119 Emerin X 154379197-154381523 Disease related genes, Predicted membrane proteins Evidence at protein level HPA000609, CAB001545, CAB002029, CAB062552 Supported Validated Nuclear membrane
Endoplasmic reticulum Expressed in all Expressed in all fallopian tube: 32.3 EMG1 C2F, Grcc2f, NEP1 ENSG00000126749 EMG1 N1-specific pseudouridine methyltransferase 12 6970893-6979941 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039304, HPA039666 Supported Validated Nucleus
Nucleoli Renal cancer:2.83e-6 (unfavourable), Liver cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all appendix: 21.6 EMILIN1 DKFZp586M121, gp115 ENSG00000138080 Elastin microfibril interfacer 1 2 27078567-27086408 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002822 Supported Renal cancer:8.13e-9 (unfavourable) Expressed in all Expressed in all seminal vesicle: 73.3 EML2 ELP70, EMAP-2, EMAP2 ENSG00000125746 Echinoderm microtubule associated protein like 2 19 45606994-45645629 Predicted intracellular proteins Evidence at protein level HPA012757 Approved Approved Vesicles Expressed in all Expressed in all parathyroid gland: 98.7 EML3 ELP95, FLJ35827 ENSG00000149499 Echinoderm microtubule associated protein like 3 11 62602218-62612765 Predicted intracellular proteins Evidence at protein level Renal cancer:3.13e-8 (unfavourable) Expressed in all Expressed in all appendix: 38.9 EMP1 CL-20, TMP ENSG00000134531 Epithelial membrane protein 1 12 13196716-13219939 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051931, HPA056250 Approved Nucleoplasm Ovarian cancer:2.26e-8 (unfavourable), Urothelial cancer:9.69e-8 (unfavourable), Pancreatic cancer:7.46e-4 (unfavourable) Expressed in all Expressed in all esophagus: 2208.3 EMP3 YMP ENSG00000142227 Epithelial membrane protein 3 19 48321509-48330553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051163 Approved Nuclear bodies Renal cancer:2.31e-7 (unfavourable), Stomach cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 199.1 ENDOD1 KIAA0830 ENSG00000149218 Endonuclease domain containing 1 11 95089810-95132645 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA008932, HPA010517 Supported Approved Nuclear membrane Renal cancer:6.64e-7 (favourable), Urothelial cancer:3.27e-4 (unfavourable), Pancreatic cancer:8.86e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 97.8 ENDOG ENSG00000167136 Endonuclease G 9 128818474-128822677 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA021335, HPA021830 Approved Renal cancer:1.06e-7 (favourable), Endometrial cancer:5.12e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 45.8 ENDOV FLJ35220 ENSG00000173818 Endonuclease V 17 80415165-80438086 Predicted intracellular proteins Evidence at protein level Breast cancer:4.24e-5 (favourable), Colorectal cancer:4.40e-4 (unfavourable) Expressed in all Expressed in all testis: 22.3 ENG CD105, END, HHT1, ORW, ORW1 ENSG00000106991 Endoglin 9 127815012-127854756 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB000096, HPA011862, HPA067440, CAB072873 Supported Liver cancer:5.62e-6 (favourable), Renal cancer:4.26e-4 (unfavourable), Head and neck cancer:6.61e-4 (favourable) Expressed in all Expressed in all spleen: 170.7 ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase 17 79074939-79088599 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021551 Approved Approved Centrosome
Cytosol Renal cancer:8.97e-6 (unfavourable), Urothelial cancer:8.73e-5 (favourable), Pancreatic cancer:2.60e-4 (favourable) Expressed in all Expressed in all spleen: 28.6 ENKD1 C16orf48, DKFZP434A1319 ENSG00000124074 Enkurin domain containing 1 16 67662945-67667265 Predicted intracellular proteins Evidence at protein level HPA041163, HPA041478 Approved Supported Plasma membrane
Centrosome
Cytosol Endometrial cancer:1.68e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 32.0 ENO1 ENO1L1, MBP-1, MPB1, PPH ENSG00000074800 Enolase 1, (alpha) 1 8861002-8879249 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018614, HPA068284, CAB069394 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.30e-8 (unfavourable), Glioma:2.12e-4 (unfavourable) Expressed in all Expressed in all appendix: 789.1 ENOPH1 E1, MASA, mtnC ENSG00000145293 Enolase-phosphatase 1 4 82430562-82461091 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004985, HPA044607 Supported Approved Nucleoplasm
Nuclear bodies Liver cancer:1.74e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 98.6 ENOX2 APK1, COVA1, tNOX ENSG00000165675 Ecto-NOX disulfide-thiol exchanger 2 X 130623369-130903317 Predicted intracellular proteins Evidence at protein level HPA000514 Uncertain Approved Nucleus
Actin filaments Renal cancer:1.09e-5 (favourable) Expressed in all Expressed in all endometrium: 19.9 ENPP2 ATX, PD-IALPHA, PDNP2 ENSG00000136960 Ectonucleotide pyrophosphatase/phosphodiesterase 2 8 119557086-119673453 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023700, HPA053652 Approved Approved Nucleus
Golgi apparatus
Actin filaments Pancreatic cancer:2.07e-5 (favourable) Expressed in all Expressed in all placenta: 372.6 ENPP4 KIAA0879, NPP4 ENSG00000001561 Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 6 46129993-46146699 Enzymes, Predicted membrane proteins Evidence at protein level HPA016594 Approved Renal cancer:6.95e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 37.8 ENSA ARPP-19e, MGC4319, MGC78563, MGC8394 ENSG00000143420 Endosulfine alpha 1 150600851-150629612 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051294 Uncertain Approved Nucleus
Nucleoli
Microtubules
Cytosol Cervical cancer:8.24e-4 (favourable) Expressed in all Expressed in all esophagus: 268.4 ENTHD2 C17orf56, FLJ31528 ENSG00000167302 ENTH domain containing 2 17 81228277-81239091 Predicted intracellular proteins Evidence at protein level HPA063410 Supported Nuclear membrane
Nuclear speckles
Golgi apparatus Renal cancer:7.31e-8 (unfavourable), Pancreatic cancer:6.95e-4 (favourable), Head and neck cancer:9.96e-4 (favourable) Expressed in all Expressed in all spleen: 15.1 ENTPD4 KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase ENSG00000197217 Ectonucleoside triphosphate diphosphohydrolase 4 8 23385783-23457695 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017655 Supported Supported Vesicles Expressed in all Expressed in all parathyroid gland: 46.4 ENTPD6 CD39L2, dJ738P15.3, IL6ST2, NTPDase-6 ENSG00000197586 Ectonucleoside triphosphate diphosphohydrolase 6 (putative) 20 25195693-25226729 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015491, HPA069555 Approved Supported Golgi apparatus Expressed in all Expressed in all cerebral cortex: 106.0 ENY2 DC6, FLJ20480, Sus1 ENSG00000120533 Enhancer of yellow 2 homolog (Drosophila) 8 109334324-109345953 Predicted intracellular proteins, Transporters Evidence at protein level HPA024648 Approved Approved Nucleoplasm
Mitochondria Renal cancer:7.17e-6 (unfavourable) Expressed in all Expressed in all kidney: 77.0 EOGT AER61, C3orf64, FLJ33770 ENSG00000163378 EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 3 68975214-69013961 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA019460 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Renal cancer:8.97e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 49.6 EP300 KAT3B, p300 ENSG00000100393 E1A binding protein p300 22 41091786-41180079 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB000146, HPA003128, HPA004112 Supported Validated Nucleoplasm Renal cancer:7.45e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 45.3 EP400 CAGH32, DKFZP434I225, KIAA1498, KIAA1818, P400, TNRC12 ENSG00000183495 E1A binding protein p400 12 131949920-132081102 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016704, HPA049013 Supported Supported Nucleus Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all testis: 20.8 EPAS1 bHLHe73, HIF2A, HLF, MOP2, PASD2 ENSG00000116016 Endothelial PAS domain protein 1 2 46293667-46386703 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031200 Approved Nucleoplasm
Cytosol Renal cancer:2.63e-4 (favourable) Expressed in all Expressed in all placenta: 636.7 EPB41 4.1R, EL1 ENSG00000159023 Erythrocyte membrane protein band 4.1 1 28887091-29120046 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA028076, HPA028412, HPA028414 Supported Supported Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.75e-6 (unfavourable), Endometrial cancer:4.58e-4 (unfavourable), Head and neck cancer:5.87e-4 (favourable) Expressed in all Expressed in all lymph node: 51.3 EPB41L2 4.1-G ENSG00000079819 Erythrocyte membrane protein band 4.1-like 2 6 130839347-131063322 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005730, HPA006642 Supported Validated Nucleus
Plasma membrane
Cell Junctions Liver cancer:2.41e-5 (unfavourable), Ovarian cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 139.6 EPB41L3 4.1B, DAL1, KIAA0987 ENSG00000082397 Erythrocyte membrane protein band 4.1-like 3 18 5392381-5630700 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028605 Approved Validated Plasma membrane Mixed Expressed in all testis: 121.4 EPB41L4A NBL4 ENSG00000129595 Erythrocyte membrane protein band 4.1 like 4A 5 112142441-112419316 Predicted intracellular proteins Evidence at protein level HPA036580 Uncertain Approved Nucleoplasm
Plasma membrane Renal cancer:3.65e-5 (favourable) Mixed Expressed in all parathyroid gland: 26.9 EPC1 Epl1 ENSG00000120616 Enhancer of polycomb homolog 1 (Drosophila) 10 32267751-32378798 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:6.02e-4 (favourable), Head and neck cancer:6.40e-4 (favourable) Expressed in all Expressed in all endometrium: 32.6 EPC2 DKFZP566F2124 ENSG00000135999 Enhancer of polycomb homolog 2 (Drosophila) 2 148644440-148787568 Predicted intracellular proteins Evidence at protein level HPA036759 Uncertain Approved Nuclear speckles Expressed in all Expressed in all endometrium: 44.0 EPDR1 EPDR, MERP-1, MERP1, UCC1 ENSG00000086289 Ependymin related 1 7 37683843-37951941 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026298 Approved Urothelial cancer:1.00e-4 (unfavourable), Stomach cancer:3.43e-4 (unfavourable), Liver cancer:6.97e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 73.6 EPHB4 HTK, Tyro11 ENSG00000196411 EPH receptor B4 7 100802565-100827521 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB013537 Uncertain Colorectal cancer:4.33e-4 (unfavourable), Breast cancer:8.56e-4 (unfavourable), Urothelial cancer:8.84e-4 (unfavourable) Expressed in all Expressed in all placenta: 50.3 EPHX1 EPHX ENSG00000143819 Epoxide hydrolase 1, microsomal (xenobiotic) 1 225810092-225845563 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020593, HPA048847 Supported Lung cancer:7.02e-5 (favourable), Prostate cancer:1.32e-4 (favourable) Tissue enriched Expressed in all adrenal gland: 1091.2 EPHX2 ENSG00000120915 Epoxide hydrolase 2, cytoplasmic 8 27490779-27545564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023094, HPA023660 Approved Validated Cytosol Renal cancer:1.98e-10 (favourable), Cervical cancer:2.45e-4 (favourable) Expressed in all Expressed in all kidney: 170.3 EPM2AIP1 FLJ11207, KIAA0766 ENSG00000178567 EPM2A (laforin) interacting protein 1 3 36985043-36993168 Predicted intracellular proteins Evidence at protein level Cervical cancer:2.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 35.6 EPN1 ENSG00000063245 Epsin 1 19 55675226-55709858 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009729, HPA061136 Approved Validated Cytosol Expressed in all Expressed in all duodenum: 91.9 EPN2 EHB21, KIAA1065 ENSG00000072134 Epsin 2 17 19215615-19336715 Predicted intracellular proteins Evidence at protein level HPA049809, HPA053360 Approved Supported Vesicles Urothelial cancer:8.15e-5 (unfavourable), Renal cancer:9.13e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 95.3 EPRS EARS, GLUPRORS, PARS, QARS, QPRS ENSG00000136628 Glutamyl-prolyl-tRNA synthetase 1 219968601-220046658 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026490, HPA030052 Supported Validated Cytosol Urothelial cancer:2.62e-4 (unfavourable), Breast cancer:7.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 118.2 EPS15 AF-1P, MLLT5 ENSG00000085832 Epidermal growth factor receptor pathway substrate 15 1 51354263-51519328 Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008451, CAB010164 Approved Validated Vesicles
Cytosol Cervical cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all testis: 84.3 EPS15L1 eps15R ENSG00000127527 Epidermal growth factor receptor pathway substrate 15-like 1 19 16355239-16472085 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019237, HPA055309 Uncertain Approved Vesicles Renal cancer:8.10e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 25.7 EPT1 KIAA1724, SELI, SEPI ENSG00000138018 Ethanolaminephosphotransferase 1 2 26308547-26395891 Enzymes, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 33.1 ERAL1 HERA-B ENSG00000132591 Era-like 12S mitochondrial rRNA chaperone 1 17 28854938-28861067 Predicted intracellular proteins Evidence at protein level HPA021425, HPA024423 Supported Validated Mitochondria
Cytosol Liver cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.2 ERAP1 A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP ENSG00000164307 Endoplasmic reticulum aminopeptidase 1 5 96760810-96808100 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025095, HPA042317 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all placenta: 68.5 ERBB2 CD340, HER-2, HER2, NEU, NGL ENSG00000141736 Erb-b2 receptor tyrosine kinase 2 17 39687914-39730426 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555 Approved Supported Plasma membrane
Cytosol Renal cancer:2.41e-14 (favourable), Endometrial cancer:8.99e-8 (unfavourable), Pancreatic cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 122.9 ERBB2IP ERBIN, LAP2 ENSG00000112851 Erbb2 interacting protein 5 65926475-66082549 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA048606, HPA059863 Approved Supported Nuclear speckles
Plasma membrane Expressed in all Expressed in all testis: 49.9 ERCC1 RAD10 ENSG00000012061 Excision repair cross-complementation group 1 19 45407333-45478828 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004390, HPA029773, HPA050182, CAB072859, CAB072860 Supported Validated Nucleoplasm Renal cancer:9.00e-5 (unfavourable), Liver cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all skin: 71.4 ERCC2 EM9, MAG, MGC102762, MGC126218, MGC126219, TFIIH, XPD ENSG00000104884 Excision repair cross-complementation group 2 19 45349837-45370918 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005375, HPA038057, HPA069266 Approved Supported Nucleoplasm Pancreatic cancer:3.26e-4 (favourable) Expressed in all Expressed in all testis: 16.2 ERCC3 BTF2, GTF2H, RAD25, TFIIH, XPB ENSG00000163161 Excision repair cross-complementation group 3 2 127257290-127294176 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB037153, HPA046077 Approved Validated Nucleoplasm Liver cancer:1.62e-7 (unfavourable), Renal cancer:4.30e-6 (unfavourable) Expressed in all Expressed in all testis: 54.8 ERCC5 ERCM2, XPGC ENSG00000134899 Excision repair cross-complementation group 5 13 102844844-102876001 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045845, HPA050374 Supported Approved Nucleoplasm Renal cancer:2.96e-6 (unfavourable), Urothelial cancer:6.82e-4 (favourable) Expressed in all Expressed in all spleen: 38.2 ERCC6L2 C9orf102, FLJ37706, RAD26L ENSG00000182150 Excision repair cross-complementation group 6-like 2 9 95875701-96014571 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021260 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:8.70e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 27.0 ERF PE-2, PE2 ENSG00000105722 Ets2 repressor factor 19 42247572-42255157 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058532, HPA067952 Approved Validated Nucleoplasm Breast cancer:8.07e-4 (favourable) Expressed in all Expressed in all gallbladder: 79.2 ERG erg-3, p55 ENSG00000157554 V-ets avian erythroblastosis virus E26 oncogene homolog 21 38380027-38661780 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB018377, HPA046598 Approved Approved Nucleoplasm
Cytosol Cervical cancer:6.18e-6 (unfavourable), Renal cancer:3.94e-4 (unfavourable) Expressed in all Expressed in all spleen: 37.3 ERGIC1 ERGIC-32, ERGIC32, KIAA1181, NET24 ENSG00000113719 Endoplasmic reticulum-golgi intermediate compartment 1 5 172834275-172952685 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018666, HPA018900 Supported Validated Nucleoplasm
Vesicles Expressed in all Expressed in all prostate: 238.4 ERGIC2 Erv41, PTX1 ENSG00000087502 ERGIC and golgi 2 12 29337352-29381189 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049695 Approved Supported Nucleoli
Vesicles Renal cancer:3.76e-6 (unfavourable), Pancreatic cancer:7.02e-6 (unfavourable), Liver cancer:8.06e-6 (unfavourable), Ovarian cancer:8.18e-4 (favourable) Expressed in all Expressed in all testis: 105.6 ERGIC3 C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84 ENSG00000125991 ERGIC and golgi 3 20 35542021-35557634 Predicted membrane proteins Evidence at protein level HPA015242, HPA015968 Approved Supported Nucleoplasm Liver cancer:2.20e-7 (unfavourable), Renal cancer:9.81e-5 (unfavourable) Expressed in all Expressed in all epididymis: 520.8 ERH DROER ENSG00000100632 Enhancer of rudimentary homolog (Drosophila) 14 69380123-69398627 Predicted intracellular proteins Evidence at protein level HPA002567 Approved Approved Nucleoplasm
Cytosol Liver cancer:7.89e-5 (unfavourable) Expressed in all Expressed in all endometrium: 111.5 ERI2 EXOD1, KIAA1504, MGC16943, ZGRF5 ENSG00000196678 ERI1 exoribonuclease family member 2 16 20780193-20900349 Predicted intracellular proteins Evidence at protein level HPA035384, HPA035385 Uncertain Supported Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 22.9 ERI3 FLJ22943, PINT1, PRNPIP ENSG00000117419 ERI1 exoribonuclease family member 3 1 44221070-44355260 Predicted intracellular proteins Evidence at protein level HPA027147, HPA029895 Approved Approved Nucleoplasm
Cytosol Liver cancer:2.04e-6 (unfavourable), Endometrial cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 81.3 ERICH1 ENSG00000104714 Glutamate-rich 1 8 614746-738106 Predicted intracellular proteins Evidence at protein level HPA003725 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all lymph node: 24.6 ERLEC1 C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB ENSG00000068912 Endoplasmic reticulum lectin 1 2 53787044-53818819 Predicted intracellular proteins, Transporters Evidence at protein level HPA031501, HPA031502, HPA031503 Approved Expressed in all Expressed in all thyroid gland: 121.4 ERLIN1 C10orf69, Erlin-1, KE04, SPFH1, SPG62 ENSG00000107566 ER lipid raft associated 1 10 100150094-100188334 Predicted secreted proteins Evidence at protein level HPA011252 Approved Supported Endoplasmic reticulum Lung cancer:7.63e-4 (unfavourable) Expressed in all Expressed in all placenta: 56.8 ERLIN2 C8orf2, Erlin-2, NET32, SPFH2, SPG18 ENSG00000147475 ER lipid raft associated 2 8 37736599-37759101 Disease related genes, Predicted secreted proteins Evidence at protein level HPA002025, CAB014894 Supported Supported Endoplasmic reticulum Renal cancer:6.67e-6 (favourable), Glioma:1.96e-4 (unfavourable), Colorectal cancer:5.16e-4 (favourable) Expressed in all Expressed in all thyroid gland: 80.6 ERMARD C6orf70, dJ266L20.3, FLJ11152 ENSG00000130023 ER membrane-associated RNA degradation 6 169751622-169781584 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041741 Approved Approved Cytosol Expressed in all Expressed in all testis: 33.0 ERN1 IRE1, IRE1P ENSG00000178607 Endoplasmic reticulum to nucleus signaling 1 17 64039142-64130819 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009495, HPA027730 Supported Renal cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 53.7 ERO1A ERO1-alpha, Ero1alpha, ERO1L ENSG00000197930 Endoplasmic reticulum oxidoreductase alpha 14 52639916-52695900 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026653, HPA030053, CAB034294 Supported Renal cancer:6.54e-9 (unfavourable), Lung cancer:1.10e-5 (unfavourable), Pancreatic cancer:2.27e-4 (unfavourable), Liver cancer:7.59e-4 (unfavourable), Cervical cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all esophagus: 182.3 ERO1B ERO1-L(beta), Ero1beta, ERO1LB ENSG00000086619 Endoplasmic reticulum oxidoreductase beta 1 236215555-236281985 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028085 Approved Lung cancer:7.53e-5 (favourable) Expressed in all Expressed in all testis: 51.2 ERP29 C12orf8, ERp28, ERp29, ERp31, PDI-DB, PDIA9 ENSG00000089248 Endoplasmic reticulum protein 29 12 112013316-112023451 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039363, HPA039456 Supported Uncertain Nucleoplasm
Microtubules Endometrial cancer:7.43e-5 (favourable), Liver cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 149.3 ERP44 KIAA0573, PDIA10, TXNDC4 ENSG00000023318 Endoplasmic reticulum protein 44 9 99979179-100099040 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA001318 Supported Head and neck cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all epididymis: 47.1 ERRFI1 GENE-33, MIG-6, RALT ENSG00000116285 ERBB receptor feedback inhibitor 1 1 8004404-8026308 Predicted intracellular proteins Evidence at protein level HPA027206 Supported Cytosol Expressed in all Expressed in all liver: 369.0 ERVK3-1 HERV-K(HML6-1) ENSG00000142396 Endogenous retrovirus group K3, member 1 19 58305319-58315663 Predicted intracellular proteins Evidence at transcript level Renal cancer:7.38e-4 (unfavourable), Liver cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all breast: 49.7 ESAM W117m ENSG00000149564 Endothelial cell adhesion molecule 11 124752583-124762290 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA051043, HPA056293 Uncertain Approved Microtubules Expressed in all Expressed in all placenta: 156.5 ESCO1 EFO1, ESO1, KIAA1911 ENSG00000141446 Establishment of sister chromatid cohesion N-acetyltransferase 1 18 21529281-21600884 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042497 Approved Expressed in all Expressed in all testis: 36.4 ESD ENSG00000139684 Esterase D 13 46771256-46797232 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039700 Approved Approved Golgi apparatus
Cytosol Head and neck cancer:2.16e-4 (unfavourable), Cervical cancer:5.01e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 244.5 ESF1 bA526K24.1, C20orf6 ENSG00000089048 ESF1 nucleolar pre-rRNA processing protein homolog 20 13714322-13784886 Predicted intracellular proteins Evidence at protein level HPA047083, HPA050396 Supported Approved Nucleus
Nucleoli Liver cancer:7.81e-9 (unfavourable) Expressed in all Expressed in all testis: 25.8 ESRRA ERR1, ERRa, ERRalpha, ESRL1, NR3B1 ENSG00000173153 Estrogen-related receptor alpha 11 64305572-64316743 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053785 Approved Nucleus
Nucleoli fibrillar center
Microtubules
Cytokinetic bridge Renal cancer:1.34e-7 (favourable) Expressed in all Expressed in all duodenum: 89.0 ESYT1 FAM62A, KIAA0747, MBC2 ENSG00000139641 Extended synaptotagmin-like protein 1 12 56118250-56144671 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016858, HPA076926 Approved Supported Endoplasmic reticulum
Vesicles Renal cancer:3.86e-4 (favourable) Expressed in all Expressed in all adipose tissue: 114.2 ESYT2 CHR2SYT, FAM62B, KIAA1228 ENSG00000117868 Extended synaptotagmin-like protein 2 7 158730995-158830253 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA002132 Approved Uncertain Cytosol Urothelial cancer:2.81e-5 (unfavourable), Pancreatic cancer:5.73e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 79.8 ETAA1 ETAA16 ENSG00000143971 Ewing tumor-associated antigen 1 2 67397319-67410545 Predicted intracellular proteins Evidence at protein level HPA035048, HPA035049 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 15.6 ETF1 ERF, ERF1, RF1, SUP45L1, TB3-1 ENSG00000120705 Eukaryotic translation termination factor 1 5 138506095-138543300 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011686, HPA037511 Approved Colorectal cancer:9.33e-5 (favourable), Thyroid cancer:1.22e-4 (unfavourable), Liver cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all testis: 108.1 ETFA EMA, GA2, MADD ENSG00000140374 Electron-transfer-flavoprotein, alpha polypeptide 15 76215355-76311472 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018990, HPA018993, HPA018996, HPA024089 Supported Validated Mitochondria Renal cancer:5.04e-8 (favourable) Expressed in all Expressed in all liver: 196.7 ETFB ENSG00000105379 Electron-transfer-flavoprotein, beta polypeptide 19 51345169-51366418 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018910, HPA018921, HPA018923 Supported Validated Mitochondria Renal cancer:6.45e-5 (favourable), Cervical cancer:6.45e-4 (favourable) Expressed in all Expressed in all liver: 171.8 ETFDH ETFQO ENSG00000171503 Electron-transferring-flavoprotein dehydrogenase 4 158672125-158709623 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041978 Supported Renal cancer:5.76e-10 (favourable) Expressed in all Expressed in all liver: 99.6 ETHE1 HSCO, YF13H12 ENSG00000105755 Ethylmalonic encephalopathy 1 19 43506719-43527244 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028360, HPA029028, HPA029029 Supported Validated Mitochondria Lung cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all colon: 244.2 ETNK1 EKI, EKI1 ENSG00000139163 Ethanolamine kinase 1 12 22625075-22690665 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010712, HPA029407 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:1.75e-4 (favourable), Liver cancer:5.85e-4 (unfavourable) Expressed in all Expressed in all stomach: 45.8 ETS1 ETS-1, EWSR2, FLJ10768 ENSG00000134954 V-ets avian erythroblastosis virus E26 oncogene homolog 1 11 128458761-128587558 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB002575, HPA063230 Supported Validated Nucleoplasm Renal cancer:1.30e-5 (unfavourable) Expressed in all Expressed in all lymph node: 324.7 ETS2 ENSG00000157557 V-ets avian erythroblastosis virus E26 oncogene homolog 2 21 38805307-38824955 Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level HPA003176 Supported Nucleoplasm
Plasma membrane Expressed in all Expressed in all spleen: 256.3 ETV3 PE-1 ENSG00000117036 Ets variant 3 1 157121191-157138474 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004794 Supported Approved Nucleus Expressed in all Expressed in all parathyroid gland: 44.9 ETV6 TEL ENSG00000139083 Ets variant 6 12 11649854-11895402 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000264 Supported Validated Nucleoli
Cytosol Renal cancer:4.66e-8 (unfavourable), Urothelial cancer:1.54e-5 (favourable), Pancreatic cancer:9.38e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 26.5 EVI5L ENSG00000142459 Ecotropic viral integration site 5-like 19 7830233-7864976 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043099, HPA043563 Approved Approved Nuclear bodies Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 41.7 EVL RNB6 ENSG00000196405 Enah/Vasp-like 14 99971449-100144236 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018849, HPA019536, CAB033987 Supported Approved Vesicles
Cytosol Pancreatic cancer:4.07e-6 (favourable), Renal cancer:4.14e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 208.7 EWSR1 EWS ENSG00000182944 EWS RNA-binding protein 1 22 29268009-29300525 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004230, HPA051771, HPA062953 Supported Validated Nucleus
Nucleoli Liver cancer:1.27e-6 (unfavourable), Renal cancer:1.21e-5 (unfavourable) Expressed in all Expressed in all testis: 213.0 EXD2 C14orf114, EXDL2, FLJ10738 ENSG00000081177 Exonuclease 3'-5' domain containing 2 14 69191511-69244020 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002906, HPA005848 Uncertain Approved Intermediate filaments
Mitochondria Renal cancer:2.08e-9 (favourable), Liver cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all testis: 36.4 EXOC1 BM-102, FLJ10893, SEC3, SEC3L1, Sec3p ENSG00000090989 Exocyst complex component 1 4 55853616-55905034 Predicted intracellular proteins Evidence at protein level HPA037706, HPA044873 Uncertain Approved Plasma membrane
Microtubules
Cytosol Urothelial cancer:5.50e-5 (favourable), Liver cancer:2.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.4 EXOC2 FLJ11026, SEC5L1, Sec5p ENSG00000112685 Exocyst complex component 2 6 485133-693111 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA032093 Uncertain Supported Vesicles Expressed in all Expressed in all testis: 30.6 EXOC3 SEC6L1, Sec6p ENSG00000180104 Exocyst complex component 3 5 443158-471937 Predicted intracellular proteins Evidence at protein level HPA037880 Approved Nucleoplasm
Mitochondria Pancreatic cancer:1.54e-4 (favourable) Expressed in all Expressed in all testis: 58.2 EXOC4 KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p ENSG00000131558 Exocyst complex component 4 7 133253073-134066589 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031443, HPA031444 Approved Supported Nucleus
Nucleoli Renal cancer:6.85e-5 (favourable), Pancreatic cancer:6.19e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.0 EXOC6 DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p ENSG00000138190 Exocyst complex component 6 10 92834713-93059493 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036285, HPA059111 Approved Supported Nucleoplasm
Vesicles Renal cancer:4.66e-4 (favourable) Expressed in all Expressed in all placenta: 49.2 EXOC7 EXO70, Exo70p, KIAA1067, YJL085W ENSG00000182473 Exocyst complex component 7 17 76081017-76121576 Predicted intracellular proteins Evidence at protein level HPA022840, HPA022842 Supported Approved Vesicles
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 100.5 EXOC8 EXO84, Exo84p, SEC84 ENSG00000116903 Exocyst complex component 8 1 231332753-231337852 Predicted intracellular proteins Evidence at protein level HPA027438 Approved Supported Cytosol Expressed in all Expressed in all parathyroid gland: 17.1 EXOSC1 CGI-108, CSL4, Csl4p, hCsl4p, p13, SKI4, Ski4p ENSG00000171311 Exosome component 1 10 97436142-97446017 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038370 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:3.88e-9 (unfavourable) Expressed in all Expressed in all epididymis: 53.9 EXOSC10 p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p ENSG00000171824 Exosome component 10 1 11066618-11099881 Predicted intracellular proteins Evidence at protein level HPA028470, HPA028484, CAB037141 Supported Supported Nucleus
Nucleoli
Cytosol Liver cancer:2.49e-6 (unfavourable), Thyroid cancer:5.27e-4 (favourable) Expressed in all Expressed in all endometrium: 46.5 EXOSC2 hRrp4p, p7, RRP4, Rrp4p ENSG00000130713 Exosome component 2 9 130693721-130704894 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021756, HPA021790 Approved Supported Nucleus
Nucleoli Liver cancer:1.39e-5 (unfavourable), Endometrial cancer:4.36e-4 (unfavourable) Expressed in all Expressed in all endometrium: 21.3 EXOSC4 FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p ENSG00000178896 Exosome component 4 8 144078626-144080647 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024792 Approved Supported Intermediate filaments
Cytosol Ovarian cancer:2.23e-4 (favourable) Expressed in all Expressed in all testis: 56.3 EXOSC5 hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p ENSG00000077348 Exosome component 5 19 41386374-41397479 Predicted intracellular proteins Evidence at protein level HPA053150, HPA055677 Approved Validated Nucleus
Nucleoli Renal cancer:3.45e-7 (unfavourable) Expressed in all Expressed in all skin: 22.1 EXOSC6 EAP4, hMtr3p, MTR3, Mtr3p, p11 ENSG00000223496 Exosome component 6 16 70246778-70251930 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 22.9 EXOSC7 EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p ENSG00000075914 Exosome component 7 3 44975241-45036066 Predicted intracellular proteins Evidence at protein level HPA036182, HPA057980 Approved Supported Nuclear speckles Renal cancer:2.69e-4 (favourable) Expressed in all Expressed in all adrenal gland: 45.1 EXOSC8 bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p ENSG00000120699 Exosome component 8 13 36998816-37009613 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB034240, HPA039702, HPA043942 Uncertain Approved Mitochondria Renal cancer:8.39e-7 (unfavourable) Expressed in all Expressed in all testis: 48.4 EXOSC9 p5, p6, PM/Scl-75, PMSCL1, RRP45, Rrp45p ENSG00000123737 Exosome component 9 4 121801317-121817021 Predicted intracellular proteins Evidence at protein level HPA041838, HPA048257, CAB070171 Approved Validated Nucleus
Nucleoli Liver cancer:1.04e-4 (unfavourable), Renal cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all testis: 89.9 EXT1 LGCR, LGS, ttv ENSG00000182197 Exostosin glycosyltransferase 1 8 117794490-118111853 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044394 Uncertain Lung cancer:1.20e-5 (unfavourable), Thyroid cancer:4.64e-4 (unfavourable), Cervical cancer:7.04e-4 (unfavourable) Expressed in all Expressed in all duodenum: 32.5 EXT2 SOTV ENSG00000151348 Exostosin glycosyltransferase 2 11 44095549-44245429 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA078409 Supported Golgi apparatus Renal cancer:5.36e-6 (unfavourable), Head and neck cancer:2.50e-4 (unfavourable) Expressed in all Expressed in all placenta: 89.9 EXTL2 ENSG00000162694 Exostosin-like glycosyltransferase 2 1 100872372-100895998 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB020716, HPA068921 Approved Approved Nucleus
Cytosol Liver cancer:1.64e-5 (unfavourable) Expressed in all Expressed in all placenta: 33.9 EXTL3 botv, REGR ENSG00000012232 Exostosin-like glycosyltransferase 3 8 28600469-28755599 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025387 Approved Liver cancer:1.14e-5 (unfavourable), Renal cancer:2.47e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 36.0 EYA3 DKFZp686C132 ENSG00000158161 EYA transcriptional coactivator and phosphatase 3 1 27970344-28088696 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052432, HPA062889 Uncertain Validated Nucleoplasm Renal cancer:3.15e-6 (favourable), Head and neck cancer:5.11e-4 (favourable) Expressed in all Expressed in all testis: 20.8 EZH1 KIAA0388, KMT6B ENSG00000108799 Enhancer of zeste 1 polycomb repressive complex 2 subunit 17 42700275-42745049 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA005478 Supported Nucleoplasm Expressed in all Expressed in all ovary: 58.5 EZR VIL2 ENSG00000092820 Ezrin 6 158765741-158819412 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004035, HPA021616, CAB047324 Supported Validated Plasma membrane Renal cancer:9.56e-8 (favourable), Pancreatic cancer:1.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 528.6 F11R CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1 ENSG00000158769 F11 receptor 1 160995211-161021348 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB004671, HPA043616, HPA061700 Supported Approved Cell Junctions
Microtubules Expressed in all Expressed in all lung: 95.1 F13A1 F13A ENSG00000124491 Coagulation factor XIII, A1 polypeptide 6 6144085-6321013 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001804, CAB002155 Supported Renal cancer:6.61e-6 (unfavourable) Expressed in all Expressed in all placenta: 664.9 F2R CF2R, PAR-1, PAR1, TR ENSG00000181104 Coagulation factor II (thrombin) receptor 5 76716043-76735781 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB008973, CAB012962 Approved Renal cancer:2.21e-7 (unfavourable) Expressed in all Expressed in all spleen: 95.4 F3 CD142 ENSG00000117525 Coagulation factor III (thromboplastin, tissue factor) 1 94529225-94541800 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009438, HPA049292, HPA069132 Approved Validated Vesicles Renal cancer:2.02e-8 (unfavourable), Pancreatic cancer:1.07e-4 (unfavourable) Expressed in all Expressed in all placenta: 189.7 F8 DXS1253E, F8C, FVIII, HEMA ENSG00000185010 Coagulation factor VIII, procoagulant component X 154835788-155026940 Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB018777 Supported Expressed in all Expressed in all lung: 23.4 F8A1 DXS522E, F8A ENSG00000277203 Coagulation factor VIII-associated 1 X 154886349-154888061 Predicted intracellular proteins Evidence at protein level HPA046960 Uncertain Cervical cancer:1.67e-6 (favourable) Expressed in all Expressed in all thyroid gland: 30.0 FAAH FAAH-1 ENSG00000117480 Fatty acid amide hydrolase 1 46394265-46413848 Enzymes, Predicted membrane proteins Evidence at protein level HPA007425 Approved Uncertain Cytosol Stomach cancer:3.63e-5 (favourable), Renal cancer:4.25e-5 (favourable), Endometrial cancer:1.51e-4 (favourable) Expressed in all Expressed in all prostate: 56.6 FAAP100 C17orf70, FLJ22175 ENSG00000185504 Fanconi anemia core complex associated protein 100 17 81539885-81553961 Predicted intracellular proteins Evidence at protein level HPA023954, HPA024626, HPA026532 Uncertain Validated Nucleoplasm
Intermediate filaments
Cytosol Renal cancer:1.00e-7 (unfavourable) Expressed in all Expressed in all spleen: 22.8 FAAP20 C1orf86, FLJ31031 ENSG00000162585 Fanconi anemia core complex associated protein 20 1 2184461-2212720 Predicted intracellular proteins Evidence at protein level HPA038829 Uncertain Supported Nucleoplasm
Nuclear bodies
Cell Junctions Pancreatic cancer:2.88e-4 (favourable), Liver cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 13.2 FABP5 E-FABP, KFABP, PA-FABP ENSG00000164687 Fatty acid binding protein 5 (psoriasis-associated) 8 81280363-81284777 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB017831, CAB040577, HPA051895 Supported Supported Plasma membrane
Cytosol Renal cancer:4.69e-10 (unfavourable) Expressed in all Expressed in all esophagus: 1671.2 FADD GIG3, MORT1 ENSG00000168040 Fas (TNFRSF6)-associated via death domain 11 70203163-70207390 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001464, CAB010209 Supported Supported Nucleoplasm
Cytosol Lung cancer:2.21e-5 (unfavourable), Head and neck cancer:8.22e-5 (unfavourable), Thyroid cancer:3.45e-4 (favourable), Cervical cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all placenta: 20.2 FADS1 D5D, FADS6, FADSD5, LLCDL1, TU12 ENSG00000149485 Fatty acid desaturase 1 11 61799625-61829318 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042705 Approved Renal cancer:1.95e-9 (unfavourable), Urothelial cancer:1.33e-4 (unfavourable), Thyroid cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 89.6 FADS2 D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13 ENSG00000134824 Fatty acid desaturase 2 11 61792980-61867354 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006741 Approved Renal cancer:1.00e-7 (unfavourable), Urothelial cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 416.6 FADS3 CYB5RP, LLCDL3 ENSG00000221968 Fatty acid desaturase 3 11 61873519-61892051 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045224 Approved Renal cancer:1.50e-9 (unfavourable), Head and neck cancer:9.54e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 98.7 FAF1 CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A ENSG00000185104 Fas (TNFRSF6) associated factor 1 1 50437028-50960263 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018253, CAB072814 Approved Validated Nucleus Liver cancer:1.87e-5 (unfavourable) Expressed in all Expressed in all testis: 59.1 FAF2 ETEA, KIAA0887, UBXD8, UBXN3B ENSG00000113194 Fas associated factor family member 2 5 176447628-176510074 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065968, HPA073828 Validated Endoplasmic reticulum
Lipid droplets Lung cancer:1.38e-4 (unfavourable), Liver cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.2 FAH ENSG00000103876 Fumarylacetoacetate hydrolase (fumarylacetoacetase) 15 80152490-80186946 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041370, HPA044093 Supported Approved Cytosol Head and neck cancer:8.51e-4 (unfavourable) Expressed in all Expressed in all liver: 151.5 FAHD1 C16orf36, DKFZP566J2046 ENSG00000180185 Fumarylacetoacetate hydrolase domain containing 1 16 1826941-1840207 Enzymes, Predicted intracellular proteins Evidence at protein level CAB025530, HPA043226, HPA043534 Supported Validated Nucleus
Mitochondria Renal cancer:2.80e-14 (favourable), Colorectal cancer:8.27e-4 (favourable) Expressed in all Expressed in all kidney: 65.8 FAHD2A CGI-105 ENSG00000115042 Fumarylacetoacetate hydrolase domain containing 2A 2 95402721-95416616 Predicted intracellular proteins Evidence at protein level HPA042145, HPA044987, CAB045971, CAB045972 Supported Expressed in all Expressed in all liver: 52.6 FAHD2B DKFZp434N062 ENSG00000144199 Fumarylacetoacetate hydrolase domain containing 2B 2 97083583-97094882 Predicted intracellular proteins Evidence at protein level HPA042145, HPA044987 Approved Glioma:2.81e-4 (unfavourable) Mixed Expressed in all epididymis: 47.9 FAIM FAIM1, FLJ10582 ENSG00000158234 Fas apoptotic inhibitory molecule 3 138608606-138633376 Predicted intracellular proteins Evidence at protein level HPA042440, HPA052209 Approved Approved Plasma membrane
Cytosol Liver cancer:3.96e-5 (unfavourable), Renal cancer:6.63e-4 (favourable) Expressed in all Expressed in all fallopian tube: 60.5 FAM103A1 C15orf18, HsT19360, MGC2560, RAM ENSG00000169612 Family with sequence similarity 103, member A1 15 82986207-82991057 Predicted intracellular proteins Evidence at protein level HPA041923, HPA041948 Supported Supported Nucleoplasm Expressed in all Expressed in all epididymis: 38.1 FAM104B CXorf44, FLJ20434 ENSG00000182518 Family with sequence similarity 104, member B X 55143102-55161310 Predicted intracellular proteins Evidence at transcript level HPA049082 Approved Lung cancer:1.22e-4 (favourable), Liver cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 73.7 FAM107B C10orf45, FLJ45505, MGC11034 ENSG00000065809 Family with sequence similarity 107, member B 10 14518557-14774897 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039661, HPA058814 Uncertain Supported Nucleoplasm Expressed in all Expressed in all lymph node: 182.3 FAM109A FLJ32356 ENSG00000198324 Family with sequence similarity 109, member A 12 111360651-111369121 Predicted intracellular proteins Evidence at protein level Renal cancer:1.15e-4 (unfavourable) Expressed in all Expressed in all small intestine: 31.4 FAM111A FLJ22794, KIAA1895 ENSG00000166801 Family with sequence similarity 111, member A 11 59142748-59155039 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039529, HPA040176 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.15e-5 (unfavourable), Urothelial cancer:4.39e-4 (favourable) Expressed in all Expressed in all spleen: 46.3 FAM114A1 Noxp20 ENSG00000197712 Family with sequence similarity 114, member A1 4 38867677-38945739 Predicted intracellular proteins Evidence at protein level HPA067948, HPA069104, HPA069701 Uncertain Validated Nucleus
Golgi apparatus
Cytosol Renal cancer:3.63e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 87.5 FAM114A2 133K02, C5orf3 ENSG00000055147 Family with sequence similarity 114, member A2 5 153990128-154038936 Predicted intracellular proteins Evidence at protein level HPA035869, HPA035870 Approved Approved Vesicles Expressed in all Expressed in all testis: 68.6 FAM117A ENSG00000121104 Family with sequence similarity 117, member A 17 49710332-49789180 Predicted intracellular proteins Evidence at protein level HPA022531 Approved Approved Nucleoplasm Lung cancer:8.25e-7 (favourable), Breast cancer:5.30e-5 (favourable), Pancreatic cancer:1.81e-4 (favourable) Expressed in all Expressed in all spleen: 47.4 FAM118A bK268H5.C22.4, C22orf8, FLJ20635 ENSG00000100376 Family with sequence similarity 118, member A 22 45308968-45341955 Predicted intracellular proteins Evidence at protein level HPA003902 Uncertain Approved Intermediate filaments
Cytosol Renal cancer:1.87e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 75.3 FAM118B FLJ21103 ENSG00000197798 Family with sequence similarity 118, member B 11 126211414-126262986 Predicted intracellular proteins Evidence at protein level HPA041644, HPA042100 Approved Approved Intermediate filaments
Cytosol Liver cancer:6.67e-7 (unfavourable) Expressed in all Expressed in all testis: 37.7 FAM120A C9orf10, DNAPTP1, KIAA0183, OSSA ENSG00000048828 Family with sequence similarity 120A 9 93451722-93566107 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019734, HPA055800 Approved Validated Cytosol Renal cancer:1.08e-7 (favourable), Endometrial cancer:5.03e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 164.2 FAM120AOS C9orf10OS ENSG00000188938 Family with sequence similarity 120A opposite strand 9 93446494-93453592 Predicted intracellular proteins Evidence at transcript level HPA021475 Approved Liver cancer:2.95e-5 (unfavourable), Renal cancer:6.04e-4 (favourable) Expressed in all Expressed in all thyroid gland: 50.1 FAM120B CCPG, KIAA1838, PGCC1 ENSG00000112584 Family with sequence similarity 120B 6 170290703-170407065 Predicted intracellular proteins Evidence at protein level HPA037518, HPA037519 Uncertain Approved Nucleoplasm
Cytosol Ovarian cancer:1.60e-4 (unfavourable), Pancreatic cancer:2.70e-4 (favourable) Expressed in all Expressed in all fallopian tube: 16.3 FAM122A C9orf42, MGC17347 ENSG00000187866 Family with sequence similarity 122A 9 68780055-68784608 Predicted intracellular proteins Evidence at protein level HPA056646 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:1.34e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.0 FAM122B DKFZp686L20116, RP11-308B5.5 ENSG00000156504 Family with sequence similarity 122B X 134769566-134797232 Predicted intracellular proteins Evidence at protein level HPA000266 Approved Approved Nucleoplasm Endometrial cancer:7.19e-5 (unfavourable) Expressed in all Expressed in all testis: 66.4 FAM126A DRCTNNB1A , HCC, HYCC1, hyccin ENSG00000122591 Family with sequence similarity 126, member A 7 22889371-23014130 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042873 Approved Supported Plasma membrane
Cytosol Renal cancer:6.04e-7 (unfavourable), Stomach cancer:5.99e-4 (unfavourable), Urothelial cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all testis: 33.2 FAM127A CXX1, Mar8, MAR8C, Mart8 ENSG00000134590 Family with sequence similarity 127, member A X 135032366-135033546 Predicted intracellular proteins Evidence at protein level Pancreatic cancer:1.97e-4 (favourable), Endometrial cancer:2.69e-4 (unfavourable), Liver cancer:5.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 241.1 FAM127B CXX1b, DKFZP564B147, MAR8A ENSG00000203950 Family with sequence similarity 127, member B X 135050932-135052196 Predicted intracellular proteins Evidence at protein level Liver cancer:1.10e-5 (unfavourable), Ovarian cancer:2.71e-4 (favourable), Endometrial cancer:2.83e-4 (unfavourable), Cervical cancer:5.35e-4 (favourable) Expressed in all Expressed in all ovary: 24.6 FAM129A C1orf24, GIG39, NIBAN ENSG00000135842 Family with sequence similarity 129, member A 1 184790724-184974550 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA028172, HPA028231, HPA028657 Approved Supported Plasma membrane
Cytosol Urothelial cancer:4.52e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 105.0 FAM129B bA356B19.6, C9orf88, DKFZP434H0820, FLJ13518, FLJ22151, FLJ22298, MINERVA ENSG00000136830 Family with sequence similarity 129, member B 9 127505339-127578989 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021284, HPA021417, HPA023261, HPA024312 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all esophagus: 363.7 FAM131A C3orf40, MGC21688 ENSG00000175182 Family with sequence similarity 131, member A 3 184335926-184346275 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042800 Uncertain Approved Nucleus
Nucleoli Endometrial cancer:2.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 101.5 FAM133B MGC40405 ENSG00000234545 Family with sequence similarity 133, member B 7 92560793-92590394 Predicted intracellular proteins Evidence at protein level HPA066175, HPA069513 Approved Nucleus
Nucleoli Expressed in all Expressed in all epididymis: 34.4 FAM134A C2orf17, MGC3035 ENSG00000144567 Family with sequence similarity 134, member A 2 219176225-219185479 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011170, HPA011844 Approved Approved Cytosol Liver cancer:1.49e-4 (unfavourable), Colorectal cancer:7.95e-4 (unfavourable) Expressed in all Expressed in all testis: 142.9 FAM134B FLJ20152, JK1 ENSG00000154153 Family with sequence similarity 134, member B 5 16473038-16617058 Disease related genes, Predicted membrane proteins Evidence at protein level HPA012077 Supported Nuclear bodies
Endoplasmic reticulum Renal cancer:5.25e-10 (favourable) Expressed in all Expressed in all heart muscle: 64.0 FAM134C DKFZp686B1036, FLJ33806 ENSG00000141699 Family with sequence similarity 134, member C 17 42579513-42610623 Predicted membrane proteins Evidence at protein level HPA016492 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Endometrial cancer:1.61e-4 (favourable), Renal cancer:6.82e-4 (unfavourable) Expressed in all Expressed in all testis: 48.6 FAM136A FLJ14668 ENSG00000035141 Family with sequence similarity 136, member A 2 70295975-70302090 Predicted intracellular proteins Evidence at protein level HPA030103, HPA030104 Approved Approved Mitochondria Renal cancer:1.33e-6 (unfavourable), Liver cancer:2.66e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 34.7 FAM13A ARHGAP48, FAM13A1, KIAA0914 ENSG00000138640 Family with sequence similarity 13, member A 4 88725955-89111398 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038108, HPA038109 Uncertain Approved Nucleoli
Cell Junctions
Cytosol Urothelial cancer:4.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 113.3 FAM13B ARHGAP49, C5orf5, FAM13B1, KHCHP, N61 ENSG00000031003 Family with sequence similarity 13, member B 5 137937960-138051961 Predicted intracellular proteins Evidence at protein level HPA036525, HPA041819, HPA071936 Uncertain Approved Nucleoplasm Renal cancer:3.55e-5 (favourable) Expressed in all Expressed in all testis: 66.0 FAM149B1 KIAA0974 ENSG00000138286 Family with sequence similarity 149, member B1 10 73168166-73244504 Predicted intracellular proteins Evidence at transcript level HPA039189, HPA039859 Uncertain Approved Nucleoplasm Pancreatic cancer:7.81e-4 (unfavourable) Expressed in all Expressed in all testis: 38.1 FAM156A PRO0659, TMEM29 ENSG00000268350 Family with sequence similarity 156, member A X 52926402-52995472 Predicted intracellular proteins Evidence at protein level HPA056640, HPA056643 Approved Not detected Expressed in all skin: 63.2 FAM160A2 C11orf56, DKFZP566M1046, FLJ22665, KIAA1759 ENSG00000051009 Family with sequence similarity 160, member A2 11 6211335-6234711 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055994, HPA063987 Approved Approved Mitochondria Expressed in all Expressed in all testis: 42.2 FAM160B1 bA106M7.3, KIAA1600 ENSG00000151553 Family with sequence similarity 160, member B1 10 114821744-114899832 Predicted intracellular proteins Evidence at protein level HPA043624 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:4.02e-6 (unfavourable) Expressed in all Expressed in all testis: 34.2 FAM160B2 FLJ21801, RAI16 ENSG00000158863 Family with sequence similarity 160, member B2 8 22089159-22104898 Predicted intracellular proteins Evidence at protein level HPA025040 Approved Approved Nucleoplasm
Cytosol Head and neck cancer:4.56e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 18.4 FAM162A C3orf28, E2IG5 ENSG00000114023 Family with sequence similarity 162, member A 3 122384176-122412334 Predicted membrane proteins Evidence at protein level HPA035856, HPA058113 Approved Validated Mitochondria
Cytosol Urothelial cancer:3.93e-4 (favourable) Expressed in all Expressed in all rectum: 165.0 FAM168A KIAA0280, TCRP1 ENSG00000054965 Family with sequence similarity 168, member A 11 73400487-73598189 Predicted intracellular proteins Evidence at protein level HPA037580 Approved Approved Nucleoplasm Renal cancer:6.41e-5 (favourable), Endometrial cancer:5.51e-4 (unfavourable), Urothelial cancer:9.70e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 104.7 FAM168B KIAA0280L ENSG00000152102 Family with sequence similarity 168, member B 2 131047876-131093460 Predicted intracellular proteins Evidence at protein level HPA043778, HPA061659 Approved Renal cancer:5.30e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 112.9 FAM172A C5orf21, DKFZP564D172 ENSG00000113391 Family with sequence similarity 172, member A 5 93618069-94111699 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012299, HPA045505 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 26.9 FAM173B ENSG00000150756 Family with sequence similarity 173, member B 5 10226330-10249897 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA074513 Approved Nucleus
Vesicles Breast cancer:1.32e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.7 FAM174A TMEM157, UNQ1912 ENSG00000174132 Family with sequence similarity 174, member A 5 100535305-100586741 Predicted membrane proteins Evidence at protein level HPA019539 Approved Approved Golgi apparatus
Cytosol Glioma:3.85e-6 (unfavourable), Renal cancer:5.48e-4 (favourable) Expressed in all Expressed in all fallopian tube: 51.2 FAM175B ABRO1, Em:AC068896.4, KIAA0157 ENSG00000165660 Family with sequence similarity 175, member B 10 124801785-124836670 Predicted intracellular proteins Evidence at protein level HPA037591, HPA037592, HPA074089 Approved Approved Cytosol Expressed in all Expressed in all thyroid gland: 20.9 FAM177A1 C14orf24 ENSG00000151327 Family with sequence similarity 177, member A1 14 35044907-35113130 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053222, HPA055440 Uncertain Approved Nucleoplasm
Vesicles Ovarian cancer:8.51e-5 (favourable), Head and neck cancer:9.70e-4 (unfavourable) Expressed in all Expressed in all prostate: 102.4 FAM179B KIAA0423 ENSG00000198718 Family with sequence similarity 179, member B 14 44962208-45074431 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050849, HPA053559 Uncertain Approved Nucleoplasm Renal cancer:8.38e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 16.7 FAM188A C10orf97, CARP, DERP5, FLJ13397, my042 ENSG00000148481 Family with sequence similarity 188, member A 10 15778170-15860520 Predicted intracellular proteins Evidence at protein level HPA038400, HPA038406 Uncertain Supported Nucleoplasm
Nuclear membrane Expressed in all Expressed in all testis: 39.0 FAM192A C16orf94, NIP30 ENSG00000172775 Family with sequence similarity 192, member A 16 57152466-57186116 Predicted intracellular proteins Evidence at protein level HPA054382, HPA059652 Uncertain Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 175.6 FAM193A C4orf8, RES4-22 ENSG00000125386 Family with sequence similarity 193, member A 4 2625261-2732565 Predicted intracellular proteins Evidence at protein level HPA043116 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:4.80e-4 (favourable) Expressed in all Expressed in all testis: 41.5 FAM193B FLJ10404, KIAA1931 ENSG00000146067 Family with sequence similarity 193, member B 5 177519788-177554541 Predicted intracellular proteins Evidence at protein level HPA035848, HPA058112 Approved Validated Nucleus
Nucleoli Renal cancer:3.71e-8 (unfavourable), Urothelial cancer:1.30e-5 (favourable) Expressed in all Expressed in all skin: 60.2 FAM195B ENSG00000225663 Family with sequence similarity 195, member B 17 81822361-81833302 Predicted intracellular proteins Evidence at protein level HPA045542 Approved Approved Cytosol Pancreatic cancer:2.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 107.4 FAM198B C4orf18, DKFZp434L142, FLJ38155 ENSG00000164125 Family with sequence similarity 198, member B 4 158124474-158173318 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007227 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center
Golgi apparatus Expressed in all Expressed in all adrenal gland: 272.9 FAM199X CXorf39 ENSG00000123575 Family with sequence similarity 199, X-linked X 104166620-104195902 Predicted intracellular proteins Evidence at protein level HPA003093 Approved Approved Nucleus
Golgi apparatus
Cytosol Expressed in all Expressed in all epididymis: 42.7 FAM204A bA319I23.1, C10orf84, FLJ13188 ENSG00000165669 Family with sequence similarity 204, member A 10 118297930-118342328 Predicted intracellular proteins Evidence at protein level HPA038182, HPA062025 Approved Supported Nucleus
Nucleoli Renal cancer:8.59e-4 (unfavourable) Expressed in all Expressed in all testis: 89.0 FAM206A C9orf6, CG-8, FLJ20457, Simiate ENSG00000119328 Family with sequence similarity 206, member A 9 108934181-108950744 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035917, HPA035918 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 36.3 FAM207A C21orf70, PRED56 ENSG00000160256 Family with sequence similarity 207, member A 21 44940010-44976989 Predicted intracellular proteins Evidence at protein level CAB034178, HPA036354 Approved Approved Golgi apparatus
Vesicles Liver cancer:7.04e-4 (unfavourable), Renal cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all testis: 20.8 FAM208B bA318E3.2, C10orf18, FLJ20360, KIAA2006 ENSG00000108021 Family with sequence similarity 208, member B 10 5684838-5763740 Predicted intracellular proteins Evidence at protein level HPA038042, HPA038043, HPA061547 Uncertain Supported Nucleus
Cytosol Liver cancer:2.91e-4 (unfavourable) Expressed in all Expressed in all testis: 43.8 FAM20B GXK1, KIAA0475 ENSG00000116199 Family with sequence similarity 20, member B 1 179025804-179076562 Predicted intracellular proteins Evidence at protein level HPA007409 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 37.2 FAM20C DKFZp547D065, DMP4, IMAGE:4942737 ENSG00000177706 Family with sequence similarity 20, member C 7 192969-260745 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA019823 Approved Nucleoplasm
Golgi apparatus
Cytosol Ovarian cancer:9.40e-6 (unfavourable), Cervical cancer:8.89e-4 (unfavourable) Expressed in all Expressed in all kidney: 38.1 FAM210B C20orf108, dJ1167H4.1, DKFZP434A1114 ENSG00000124098 Family with sequence similarity 210, member B 20 56358915-56368663 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042652 Approved Approved Plasma membrane
Cytosol Renal cancer:1.44e-10 (favourable), Lung cancer:4.26e-4 (favourable), Cervical cancer:5.44e-4 (favourable) Expressed in all Expressed in all ovary: 131.1 FAM213A C10orf58, MGC4248, PAMM ENSG00000122378 Family with sequence similarity 213, member A 10 80407829-80437115 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA009025, HPA024565 Approved Urothelial cancer:6.11e-4 (favourable) Expressed in all Expressed in all adipose tissue: 424.6 FAM214A FLJ10980, KIAA1370 ENSG00000047346 Family with sequence similarity 214, member A 15 52581317-52709817 Predicted intracellular proteins Evidence at protein level HPA039369, HPA040180 Approved Approved Nucleoplasm Endometrial cancer:7.27e-6 (favourable), Lung cancer:8.68e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.9 FAM214B bA182N22.6, FLJ11560, KIAA1539 ENSG00000005238 Family with sequence similarity 214, member B 9 35104112-35116341 Predicted intracellular proteins Evidence at protein level HPA048831, HPA055751 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all bone marrow: 24.5 FAM219A bA573M23.5, C9orf25, FLJ39031 ENSG00000164970 Family with sequence similarity 219, member A 9 34398184-34458570 Predicted intracellular proteins Evidence at protein level HPA019338, HPA052909 Uncertain Supported Nucleoplasm
Golgi apparatus
Vesicles Liver cancer:1.98e-5 (unfavourable), Renal cancer:5.54e-5 (unfavourable), Pancreatic cancer:2.46e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 76.3 FAM21A bA56A21.1, bA98I6.1, FAM21B, FLJ10824 ENSG00000099290 Family with sequence similarity 21, member A 10 50067888-50133506 Predicted intracellular proteins Evidence at protein level HPA047844, HPA060975 Approved Supported Nucleoli
Vesicles
Cytosol Liver cancer:6.75e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 45.0 FAM21C Em:AC012044.3, KIAA0592 ENSG00000172661 Family with sequence similarity 21, member C 10 45727200-45792961 Predicted intracellular proteins Evidence at protein level HPA047844, HPA060975 Approved Supported Nucleoli
Vesicles
Cytosol Liver cancer:1.35e-5 (unfavourable), Lung cancer:4.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 41.2 FAM220A C7orf70, MGC12966, SIPAR ENSG00000178397 Family with sequence similarity 220, member A 7 6329409-6348981 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA055050 Approved Vesicles Liver cancer:5.17e-6 (unfavourable), Thyroid cancer:3.47e-4 (unfavourable) Expressed in all Expressed in all testis: 102.0 FAM222B C17orf63, FLJ10700 ENSG00000173065 Family with sequence similarity 222, member B 17 28755978-28855232 Predicted intracellular proteins Evidence at protein level HPA051840, HPA062239 Approved Validated Nucleoplasm Liver cancer:3.45e-4 (unfavourable) Expressed in all Expressed in all testis: 50.8 FAM227B C15orf33, FLJ32800 ENSG00000166262 Family with sequence similarity 227, member B 15 49326962-49620931 Predicted intracellular proteins Evidence at protein level HPA049774, HPA061695 Uncertain Approved Nuclear speckles Mixed Expressed in all testis: 21.3 FAM234A C16orf9, DKFZP761D0211, FLJ32603, ITFG3 ENSG00000167930 Family with sequence similarity 234, member A 16 234546-268971 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011651 Uncertain Nucleoplasm
Mitochondria Expressed in all Expressed in all duodenum: 113.8 FAM32A DKFZP586O0120 ENSG00000105058 Family with sequence similarity 32, member A 19 16185380-16192046 Predicted intracellular proteins Evidence at protein level HPA051712 Approved Supported Nucleus
Nucleoli Expressed in all Expressed in all placenta: 88.9 FAM35A bA163M19.1, FAM35A1, MGC5560 ENSG00000122376 Family with sequence similarity 35, member A 10 87094161-87191468 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036582 Uncertain Approved Nucleoplasm
Actin filaments Glioma:5.44e-4 (favourable), Colorectal cancer:6.06e-4 (favourable) Expressed in all Expressed in all thyroid gland: 38.6 FAM3A 2-19, DXS560S, XAP-7 ENSG00000071889 Family with sequence similarity 3, member A X 154506159-154516242 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025016, HPA056991 Uncertain Approved Nucleus
Nucleoli Colorectal cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all small intestine: 28.9 FAM3C GS3876, ILEI ENSG00000196937 Family with sequence similarity 3, member C 7 121348851-121396364 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043376, HPA050548 Supported Validated Golgi apparatus Expressed in all Expressed in all thyroid gland: 180.6 FAM45A ENSG00000119979 Family with sequence similarity 45, member A 10 119104086-119137984 Predicted intracellular proteins Evidence at protein level HPA041159 Approved Plasma membrane
Centrosome
Cytosol Expressed in all Expressed in all thyroid gland: 31.7 FAM47E-STBD1 ENSG00000272414 FAM47E-STBD1 readthrough 4 76251721-76311129 Predicted intracellular proteins Evidence at transcript level HPA053331 Approved Uncertain Plasma membrane
Cytosol Not detected Expressed in all adipose tissue: 33.0 FAM49B BM-009 ENSG00000153310 Family with sequence similarity 49, member B 8 129839593-130017129 Predicted intracellular proteins Evidence at protein level HPA009076 Approved Approved Nucleus
Cytosol Renal cancer:3.09e-10 (unfavourable), Liver cancer:3.02e-6 (unfavourable), Endometrial cancer:1.24e-4 (unfavourable) Expressed in all Expressed in all lymph node: 139.1 FAM50A 9F, DXS9928E, HXC-26, XAP5 ENSG00000071859 Family with sequence similarity 50, member A X 154444126-154450654 Predicted intracellular proteins Evidence at protein level HPA003585 Supported Validated Nucleoplasm Liver cancer:3.15e-5 (unfavourable), Colorectal cancer:9.52e-5 (unfavourable), Cervical cancer:2.05e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 66.2 FAM50B D6S2654E, X5L ENSG00000145945 Family with sequence similarity 50, member B 6 3849386-3851317 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064111, HPA067817 Approved Validated Nucleoplasm
Cytokinetic bridge Renal cancer:4.01e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 16.1 FAM53C C5orf6 ENSG00000120709 Family with sequence similarity 53, member C 5 138331935-138349729 Predicted intracellular proteins Evidence at protein level HPA042796 Approved Endometrial cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 73.3 FAM58A FLJ21610, MGC29729 ENSG00000262919 Family with sequence similarity 58, member A X 153587919-153600045 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050137, HPA059843 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 15.3 FAM63A FLJ11280 ENSG00000143409 Family with sequence similarity 63, member A 1 150996086-151008375 Predicted intracellular proteins Evidence at protein level HPA028351, HPA028358, HPA061086 Approved Supported Nucleoplasm Renal cancer:3.43e-8 (favourable) Expressed in all Expressed in all thyroid gland: 79.6 FAM65A FLJ13725 ENSG00000039523 Family with sequence similarity 65, member A 16 67518418-67546788 Predicted intracellular proteins Evidence at protein level HPA005923 Uncertain Approved Golgi apparatus
Cytosol Renal cancer:5.82e-8 (favourable), Lung cancer:5.00e-5 (unfavourable), Head and neck cancer:6.53e-4 (unfavourable) Expressed in all Expressed in all spleen: 60.7 FAM69B C9orf136, MGC20262 ENSG00000165716 Family with sequence similarity 69, member B 9 136712570-136724050 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046812, HPA054443 Uncertain Approved Nucleus
Nuclear bodies
Vesicles Colorectal cancer:1.77e-5 (unfavourable), Pancreatic cancer:9.48e-5 (favourable) Expressed in all Expressed in all placenta: 29.6 FAM73A FLJ35093 ENSG00000180488 Family with sequence similarity 73, member A 1 77779624-77879539 Predicted membrane proteins Evidence at protein level HPA017589 Approved Supported Mitochondria Expressed in all Expressed in all parathyroid gland: 32.2 FAM76A MGC34648 ENSG00000009780 Family with sequence similarity 76, member A 1 27725979-27763122 Predicted intracellular proteins Evidence at protein level HPA044762, HPA077897 Uncertain Approved Nucleus
Cytosol Renal cancer:2.26e-4 (favourable) Expressed in all Expressed in all testis: 32.4 FAM76B MGC33371 ENSG00000077458 Family with sequence similarity 76, member B 11 95768942-95790409 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036608 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:7.17e-5 (unfavourable), Urothelial cancer:2.72e-4 (favourable) Expressed in all Expressed in all testis: 32.9 FAM89A C1orf153, MGC15887 ENSG00000182118 Family with sequence similarity 89, member A 1 231018958-231040246 Predicted intracellular proteins Evidence at protein level HPA059052, HPA059578 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:1.75e-5 (unfavourable) Expressed in all Expressed in all placenta: 97.9 FAM89B ENSG00000176973 Family with sequence similarity 89, member B 11 65572349-65574198 Predicted intracellular proteins Evidence at protein level HPA046895 Approved Renal cancer:9.48e-5 (unfavourable), Liver cancer:2.98e-4 (unfavourable), Ovarian cancer:6.00e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 38.5 FAM8A1 AHCP ENSG00000137414 Family with sequence similarity 8, member A1 6 17600355-17611719 Predicted membrane proteins, Transporters Evidence at protein level HPA044698 Supported Golgi apparatus Expressed in all Expressed in all endometrium: 45.3 FAM91A1 FLJ23790 ENSG00000176853 Family with sequence similarity 91, member A1 8 123768456-123815452 Predicted intracellular proteins Evidence at protein level HPA027978 Approved Approved Nucleoplasm
Microtubules Expressed in all Expressed in all parathyroid gland: 36.1 FAM96A FLJ22875 ENSG00000166797 Family with sequence similarity 96, member A 15 64072559-64094018 Predicted secreted proteins Evidence at protein level HPA040459, HPA063729 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all liver: 105.8 FAM96B CGI-128, MIP18 ENSG00000166595 Family with sequence similarity 96, member B 16 66932055-66934423 Predicted intracellular proteins Evidence at protein level HPA041501, HPA041736 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 120.4 FAM98A DKFZP564F0522 ENSG00000119812 Family with sequence similarity 98, member A 2 33583658-33599382 Predicted intracellular proteins Evidence at protein level HPA036250, HPA036251 Uncertain Supported Vesicles Liver cancer:4.86e-7 (unfavourable), Thyroid cancer:8.18e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 125.0 FAM98B FLJ38426 ENSG00000171262 Family with sequence similarity 98, member B 15 38454127-38487710 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008320, HPA008502 Approved Supported Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 31.6 FAN1 KIAA1018, MTMR15 ENSG00000198690 FANCD2/FANCI-associated nuclease 1 15 30903852-30943108 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048198 Supported Nucleoplasm
Cytokinetic bridge
Cytosol Renal cancer:1.42e-6 (favourable) Expressed in all Expressed in all prostate: 9.8 FANCL FAAP43, FLJ10335, PHF9, Pog ENSG00000115392 Fanconi anemia, complementation group L 2 58159243-58241372 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB033842, HPA036685, HPA036686 Supported Approved Nuclear bodies
Vesicles Renal cancer:1.12e-7 (unfavourable), Liver cancer:2.81e-7 (unfavourable), Urothelial cancer:7.80e-5 (favourable) Expressed in all Expressed in all adrenal gland: 44.8 FAR1 FLJ22728, MLSTD2, SDR10E1 ENSG00000197601 Fatty acyl CoA reductase 1 11 13668670-13732346 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017322 Approved Validated Peroxisomes Colorectal cancer:2.27e-4 (favourable) Expressed in all Expressed in all stomach: 59.0 FARP2 FIR, FRG, KIAA0793, PLEKHC3 ENSG00000006607 FERM, RhoGEF and pleckstrin domain protein 2 2 241356243-241494841 Predicted intracellular proteins Evidence at protein level HPA031226, HPA055592 Approved Approved Cytosol Expressed in all Expressed in all testis: 37.3 FARS2 dJ236A3.1, FARS1 ENSG00000145982 Phenylalanyl-tRNA synthetase 2, mitochondrial 6 5261044-5771580 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018148, HPA028836 Approved Approved Plasma membrane Renal cancer:1.24e-6 (favourable), Colorectal cancer:5.14e-4 (favourable) Expressed in all Expressed in all thyroid gland: 24.3 FARSA CML33, FARSL, FARSLA ENSG00000179115 Phenylalanyl-tRNA synthetase, alpha subunit 19 12922479-12934037 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001911 Approved Supported Cytosol Cervical cancer:8.23e-4 (favourable), Stomach cancer:8.32e-4 (favourable), Endometrial cancer:9.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 67.4 FARSB FARSLB, FRSB, PheHB ENSG00000116120 Phenylalanyl-tRNA synthetase, beta subunit 2 222570536-222656337 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036677, HPA036678, HPA061398 Supported Supported Nucleus
Cytosol Liver cancer:6.45e-10 (unfavourable), Renal cancer:3.21e-5 (unfavourable), Urothelial cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all testis: 34.3 FASN FAS, SDR27X1 ENSG00000169710 Fatty acid synthase 17 82078333-82098332 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005192, HPA006461, CAB015417, HPA056108 Supported Validated Plasma membrane
Cytosol Cervical cancer:1.42e-5 (unfavourable), Renal cancer:7.16e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 283.6 FASTK FAST ENSG00000164896 Fas-activated serine/threonine kinase 7 151076593-151080866 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031621, CAB032539 Approved Approved Nuclear speckles
Mitochondria Pancreatic cancer:3.99e-4 (favourable), Colorectal cancer:4.73e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 41.7 FASTKD1 FLJ21901 ENSG00000138399 FAST kinase domains 1 2 169529749-169573875 Predicted intracellular proteins Evidence at protein level HPA043719 Approved Approved Nucleoplasm Expressed in all Expressed in all rectum: 27.1 FASTKD2 KIAA0971 ENSG00000118246 FAST kinase domains 2 2 206765357-206792509 Predicted intracellular proteins Evidence at protein level HPA067191 Supported Mitochondria Liver cancer:8.29e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 30.0 FASTKD5 FLJ13149 ENSG00000215251 FAST kinase domains 5 20 3146519-3159897 Predicted intracellular proteins Evidence at protein level HPA043833 Approved Renal cancer:8.19e-8 (favourable), Liver cancer:4.05e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 22.9 FAU asr1, FLJ22986, Fub1, Fubi, MNSFbeta, RPS30, S30 ENSG00000149806 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 11 65120628-65122473 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA059015 Supported Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 1268.2 FBL FIB, FLRN, RNU3IP1 ENSG00000105202 Fibrillarin 19 39834458-39846414 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001514, HPA049546 Supported Validated Nucleoli fibrillar center Renal cancer:4.52e-6 (unfavourable), Liver cancer:1.32e-4 (unfavourable), Breast cancer:1.65e-4 (favourable) Expressed in all Expressed in all ovary: 213.7 FBLN1 FBLN ENSG00000077942 Fibulin 1 22 45502238-45601135 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001612, HPA001613, CAB004393, CAB068187 Supported Approved Endoplasmic reticulum Renal cancer:3.02e-10 (unfavourable), Endometrial cancer:9.28e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 1317.9 FBLN5 ARMD3, DANCE, EVEC, UP50 ENSG00000140092 Fibulin 5 14 91869412-91947987 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA000848, HPA000868, CAB025843 Supported Approved Plasma membrane
Cytosol Liver cancer:6.75e-4 (favourable) Expressed in all Expressed in all gallbladder: 221.9 FBRS FBS, FBS1, FLJ11618 ENSG00000156860 Fibrosin 16 30658431-30670814 Predicted intracellular proteins Evidence at protein level HPA044117 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 78.2 FBRSL1 KIAA1545 ENSG00000112787 Fibrosin-like 1 12 132489551-132585188 Predicted intracellular proteins Evidence at protein level HPA049880 Approved Approved Nucleus
Plasma membrane
Cytosol Renal cancer:1.17e-4 (favourable), Urothelial cancer:7.21e-4 (favourable), Prostate cancer:9.82e-4 (unfavourable) Expressed in all Expressed in all spleen: 11.5 FBXL12 Fbl12, FLJ20188 ENSG00000127452 F-box and leucine-rich repeat protein 12 19 9810267-9827816 Predicted intracellular proteins Evidence at protein level HPA002843 Approved Mitochondria Liver cancer:1.41e-4 (unfavourable), Head and neck cancer:3.21e-4 (favourable), Melanoma:4.96e-4 (unfavourable) Expressed in all Expressed in all placenta: 21.7 FBXL14 Fbl14, MGC40195 ENSG00000171823 F-box and leucine-rich repeat protein 14 12 1565993-1594165 Predicted intracellular proteins Evidence at protein level HPA053889 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:9.04e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 15.3 FBXL17 DKFZP434C1715, Fbl17, Fbx13, FBXO13 ENSG00000145743 F-box and leucine-rich repeat protein 17 5 107859035-108382098 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036410, HPA036411 Uncertain Approved Nucleus Renal cancer:4.60e-8 (favourable), Thyroid cancer:3.27e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 43.5 FBXL19 CXXC11, DKFZp434K0410, Fbl19, JHDM1C ENSG00000099364 F-box and leucine-rich repeat protein 19 16 30923055-30948783 Predicted intracellular proteins Evidence at protein level HPA035317 Approved Intermediate filaments Cervical cancer:3.27e-4 (unfavourable), Liver cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all testis: 36.1 FBXL3 FBL3, FBL3A, FBXL3A ENSG00000005812 F-box and leucine-rich repeat protein 3 13 76992598-77027195 Predicted intracellular proteins Evidence at protein level HPA053283, HPA065626 Validated Nuclear bodies Expressed in all Expressed in all thyroid gland: 81.3 FBXL4 FBL4, FBL5 ENSG00000112234 F-box and leucine-rich repeat protein 4 6 98868538-98948006 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029140, CAB033362 Approved Supported Nuclear speckles Expressed in all Expressed in all parathyroid gland: 24.8 FBXL5 FBL4, FBL5, FLR1 ENSG00000118564 F-box and leucine-rich repeat protein 5 4 15604539-15681679 Predicted intracellular proteins Evidence at protein level Renal cancer:6.18e-5 (favourable) Expressed in all Expressed in all kidney: 133.4 FBXL8 Fbl8 ENSG00000135722 F-box and leucine-rich repeat protein 8 16 67159931-67164570 Predicted intracellular proteins Evidence at protein level HPA035587, HPA035588 Uncertain Approved Golgi apparatus Endometrial cancer:5.39e-4 (favourable) Expressed in all Expressed in all prostate: 25.7 FBXO11 FBX11, UBR6 ENSG00000138081 F-box protein 11 2 47789316-47905793 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002690 Uncertain Supported Nucleus Expressed in all Expressed in all testis: 74.9 FBXO18 FBH1, Fbx18, FLJ14590 ENSG00000134452 F-box protein, helicase, 18 10 5890203-5937594 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA002844 Supported Liver cancer:7.73e-7 (unfavourable) Expressed in all Expressed in all fallopian tube: 46.4 FBXO21 FBX21, KIAA0875 ENSG00000135108 F-box protein 21 12 117141988-117190531 Predicted intracellular proteins Evidence at protein level HPA062411, HPA071452 Approved Approved Mitochondria Renal cancer:2.05e-8 (favourable) Expressed in all Expressed in all fallopian tube: 202.3 FBXO22 FBX22, FISTC1 ENSG00000167196 F-box protein 22 15 75903859-75942510 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all testis: 15.2 FBXO25 FBX25 ENSG00000147364 F-box protein 25 8 406428-477967 Disease related genes, Predicted intracellular proteins Evidence at protein level Cervical cancer:5.38e-5 (favourable), Renal cancer:1.41e-4 (favourable) Expressed in all Expressed in all testis: 150.6 FBXO28 CENP-30, Fbx28, FLJ10766, KIAA0483 ENSG00000143756 F-box protein 28 1 224114087-224162047 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003289 Approved Nucleoplasm
Focal adhesion sites Expressed in all Expressed in all skin: 25.0 FBXO3 FBA, FBX3 ENSG00000110429 F-box protein 3 11 33740939-33774543 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002467 Approved Nucleoplasm
Cytosol Renal cancer:2.46e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 88.0 FBXO31 FBX14, Fbx31, FBXO14, MGC15419 ENSG00000103264 F-box protein 31 16 87326987-87392142 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030150 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Pancreatic cancer:9.16e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 23.9 FBXO33 Fbx33 ENSG00000165355 F-box protein 33 14 39397669-39432500 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046657 Approved Approved Nucleoplasm Renal cancer:4.58e-4 (favourable), Lung cancer:4.94e-4 (favourable) Expressed in all Expressed in all bone marrow: 33.4 FBXO34 Fbx34, FLJ20725 ENSG00000178974 F-box protein 34 14 55271303-55361918 Predicted intracellular proteins Evidence at protein level HPA052592 Uncertain Approved Nuclear speckles Renal cancer:1.20e-13 (favourable) Expressed in all Expressed in all testis: 46.9 FBXO38 Fbx38, FLJ13962, MOKA, SP329 ENSG00000145868 F-box protein 38 5 148383935-148442836 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034821, HPA041444 Approved Supported Nucleoplasm
Plasma membrane
Cytokinetic bridge
Cytosol Expressed in all Expressed in all parathyroid gland: 30.2 FBXO4 FBX4 ENSG00000151876 F-box protein 4 5 41925254-41941743 Predicted intracellular proteins Evidence at protein level HPA003362 Approved Nucleus Renal cancer:1.28e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 20.9 FBXO42 Fbx42, KIAA1332 ENSG00000037637 F-box protein 42 1 16246839-16352454 Predicted intracellular proteins Evidence at protein level HPA025071 Approved Approved Nucleoplasm Liver cancer:3.72e-4 (unfavourable) Expressed in all Expressed in all skin: 30.0 FBXO44 FBG3, FBX30, Fbx44, Fbxo6a, MGC14140 ENSG00000132879 F-box protein 44 1 11654375-11663327 Predicted intracellular proteins Evidence at protein level HPA003363 Approved Approved Nucleoplasm Renal cancer:6.29e-5 (favourable), Pancreatic cancer:2.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 98.3 FBXO46 20D7-FC4, Fbx46, FBXO34L ENSG00000177051 F-box protein 46 19 45710629-45730904 Predicted intracellular proteins Evidence at protein level HPA049390 Uncertain Approved Nucleus
Vesicles
Cytosol Urothelial cancer:5.09e-6 (favourable), Endometrial cancer:2.13e-5 (unfavourable), Liver cancer:1.11e-4 (unfavourable), Renal cancer:5.33e-4 (unfavourable), Head and neck cancer:5.44e-4 (favourable), Pancreatic cancer:8.11e-4 (favourable) Expressed in all Expressed in all lymph node: 17.9 FBXO6 FBG2, FBS2, FBX6, Fbx6b ENSG00000116663 F-box protein 6 1 11664124-11674354 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA051175 Approved Renal cancer:7.83e-6 (unfavourable), Urothelial cancer:5.90e-4 (favourable), Ovarian cancer:7.12e-4 (favourable) Expressed in all Expressed in all fallopian tube: 21.2 FBXO7 Fbx, FBX7, PARK15 ENSG00000100225 F-box protein 7 22 32474676-32498829 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA032113, HPA032114, CAB034296 Uncertain Supported Nucleus
Cytosol Renal cancer:2.66e-10 (favourable), Colorectal cancer:1.08e-5 (favourable) Expressed in all Expressed in all thyroid gland: 223.9 FBXO8 FBS, FBX8 ENSG00000164117 F-box protein 8 4 174236658-174284264 Predicted intracellular proteins Evidence at transcript level HPA002885 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.29e-7 (favourable) Expressed in all Expressed in all placenta: 44.1 FBXO9 FBX9, NY-REN-57 ENSG00000112146 F-box protein 9 6 53051991-53100873 Predicted intracellular proteins Evidence at protein level HPA064246 Approved Centrosome Ovarian cancer:1.51e-4 (favourable), Pancreatic cancer:1.82e-4 (favourable) Expressed in all Expressed in all adrenal gland: 108.0 FBXW11 BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696 ENSG00000072803 F-box and WD repeat domain containing 11 5 171861549-172006873 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062578, HPA072204 Approved Approved Nucleoli
Vesicles Expressed in all Expressed in all parathyroid gland: 71.3 FBXW2 FBW2, Fwd2, Md6 ENSG00000119402 F-box and WD repeat domain containing 2 9 120751978-120793412 Predicted intracellular proteins Evidence at protein level HPA067878 Approved Approved Nucleoplasm Renal cancer:1.38e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 41.7 FBXW4 dactylin, Fbw4, SHFM3 ENSG00000107829 F-box and WD repeat domain containing 4 10 101610664-101695295 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043496 Approved Approved Golgi apparatus Renal cancer:3.41e-5 (favourable), Pancreatic cancer:4.67e-4 (favourable), Endometrial cancer:4.91e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 79.6 FBXW5 DKFZP434B205, Fbw5, MGC20962 ENSG00000159069 F-box and WD repeat domain containing 5 9 136940435-136944696 Predicted intracellular proteins Evidence at protein level HPA046615 Approved Approved Mitochondria Endometrial cancer:1.02e-4 (favourable), Renal cancer:4.74e-4 (favourable) Expressed in all Expressed in all testis: 163.4 FBXW7 AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10 ENSG00000109670 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 4 152321259-152536101 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB013793, CAB029987 Supported Supported Nucleoplasm
Vesicles Renal cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all skin: 87.7 FBXW8 FBW6, FBW8, FBX29, FBXO29 ENSG00000174989 F-box and WD repeat domain containing 8 12 116910956-117031148 Predicted intracellular proteins Evidence at protein level HPA038850, HPA038851 Supported Supported Cytosol Expressed in all Expressed in all thyroid gland: 16.2 FCER1G ENSG00000158869 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1 161215234-161220699 FDA approved drug targets, Predicted membrane proteins Evidence at protein level CAB022108, HPA026872 Supported Renal cancer:1.83e-6 (unfavourable) Expressed in all Expressed in all spleen: 470.3 FCF1 Bka, C14orf111, CGI-35, UTP24 ENSG00000119616 FCF1 rRNA-processing protein 14 74713144-74738620 Predicted intracellular proteins Evidence at protein level HPA046681 Approved Approved Nucleoplasm Liver cancer:5.54e-6 (unfavourable), Renal cancer:2.26e-4 (favourable), Pancreatic cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 72.5 FCGR3A CD16, CD16a, FCG3, FCGR3 ENSG00000203747 Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1 161541759-161550737 CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB032435, HPA055431 Supported Renal cancer:3.22e-6 (unfavourable) Expressed in all Expressed in all spleen: 427.3 FCGRT alpha-chain, FCRN ENSG00000104870 Fc fragment of IgG, receptor, transporter, alpha 19 49506816-49526333 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012122, HPA015130 Approved Expressed in all Expressed in all small intestine: 318.5 FCHO2 ENSG00000157107 FCH domain only 2 5 72955981-73090522 Predicted intracellular proteins Evidence at protein level HPA037685, HPA037686, HPA077850 Supported Approved Vesicles
Centrosome
Cytosol Renal cancer:7.00e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.5 FCHSD2 KIAA0769, SH3MD3 ENSG00000137478 FCH and double SH3 domains 2 11 72836745-73142261 Predicted intracellular proteins Evidence at protein level HPA038545, HPA038546 Uncertain Approved Nuclear speckles
Plasma membrane
Actin filaments
Focal adhesion sites Colorectal cancer:1.71e-4 (favourable) Expressed in all Expressed in all spleen: 65.0 FDFT1 ENSG00000079459 Farnesyl-diphosphate farnesyltransferase 1 8 11795573-11839309 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008874 Approved Supported Endoplasmic reticulum Renal cancer:6.59e-9 (favourable), Colorectal cancer:4.92e-5 (favourable) Expressed in all Expressed in all testis: 204.4 FDPS ENSG00000160752 Farnesyl diphosphate synthase 1 155308748-155320666 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028200 Approved Approved Nucleoplasm
Cytosol Liver cancer:7.35e-4 (unfavourable) Expressed in all Expressed in all liver: 186.1 FDX1L MGC19604 ENSG00000267673 Ferredoxin 1-like 19 10310045-10316015 Predicted intracellular proteins Evidence at protein level HPA043986 Approved Expressed in all Expressed in all cerebral cortex: 47.5 FECH ENSG00000066926 Ferrochelatase 18 57548283-57586772 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044100, HPA048177 Approved Renal cancer:2.38e-10 (favourable) Expressed in all Expressed in all bone marrow: 93.5 FEM1B ENSG00000169018 Fem-1 homolog b (C. elegans) 15 68277803-68295865 Predicted intracellular proteins Evidence at protein level HPA041920, HPA042192 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 105.3 FEM1C EUROIMAGE686608, EUROIMAGE783647, FEM1A, KIAA1785 ENSG00000145780 Fem-1 homolog c (C. elegans) 5 115520908-115544894 Predicted intracellular proteins Evidence at protein level HPA059919, HPA060977 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.55e-4 (unfavourable), Colorectal cancer:1.83e-4 (favourable) Expressed in all Expressed in all bone marrow: 40.3 FES FPS ENSG00000182511 FES proto-oncogene, tyrosine kinase 15 90883695-90895776 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001376 Approved Approved Nucleus
Vesicles
Cytosol Colorectal cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all spleen: 98.1 FEZ2 ENSG00000171055 Fasciculation and elongation protein zeta 2 (zygin II) 2 36531805-36646087 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035978 Uncertain Approved Nucleoli
Golgi apparatus
Cytosol Liver cancer:7.79e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 78.9 FGD4 CMT4H, frabin, FRABP, ZFYVE6 ENSG00000139132 FYVE, RhoGEF and PH domain containing 4 12 32399529-32646050 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039235 Approved Supported Actin filaments Renal cancer:7.16e-5 (favourable) Expressed in all Expressed in all ovary: 30.1 FGFR1 BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM ENSG00000077782 Fibroblast growth factor receptor 1 8 38411138-38468834 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB033614, HPA056402, HPA076274 Approved Approved Nucleoli Expressed in all Expressed in all gallbladder: 109.6 FGFR1OP FOP ENSG00000213066 FGFR1 oncogene partner 6 166999182-167052713 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA071876 Supported Centrosome Renal cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all testis: 104.8 FGFR1OP2 DKFZp564O1863 ENSG00000111790 FGFR1 oncogene partner 2 12 26938383-26966650 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038308, HPA038696 Supported Approved Mitochondria Expressed in all Expressed in all ovary: 73.6 FGFRL1 ENSG00000127418 Fibroblast growth factor receptor-like 1 4 1009936-1026897 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026019, HPA068828 Approved Approved Nucleoplasm
Vesicles
Cytosol Expressed in all Expressed in all thyroid gland: 67.5 FGGY FLJ10986 ENSG00000172456 FGGY carbohydrate kinase domain containing 1 59296638-59810647 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA054971 Approved Nucleoplasm
Nuclear bodies Expressed in all Expressed in all epididymis: 43.6 FGL2 pT49, T49 ENSG00000127951 Fibrinogen-like 2 7 77193371-77199826 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA021011, HPA026682 Supported Expressed in all Expressed in all spleen: 228.4 FH fumarase ENSG00000091483 Fumarate hydratase 1 241497603-241519761 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB017785, HPA025770, HPA025948, HPA027341 Supported Approved Validated Mitochondria Renal cancer:2.76e-7 (favourable) Expressed in all Expressed in all liver: 141.9 FHIT AP3Aase, FRA3B ENSG00000189283 Fragile histidine triad 3 59749310-61251459 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB002684, HPA018840, HPA018909 Supported Approved Nucleoli fibrillar center
Plasma membrane Renal cancer:1.36e-4 (favourable) Mixed Expressed in all kidney: 26.6 FHL1 bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA ENSG00000022267 Four and a half LIM domains 1 X 136146702-136211359 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001040, HPA001391, CAB020817 Supported Supported Plasma membrane
Cytosol Urothelial cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 3805.6 FHL2 DRAL, SLIM3 ENSG00000115641 Four and a half LIM domains 2 2 105357712-105438513 Predicted intracellular proteins Evidence at protein level HPA005922, HPA006028, CAB008368 Supported Validated Actin filaments
Focal adhesion sites Renal cancer:6.42e-5 (unfavourable), Head and neck cancer:2.01e-4 (unfavourable) Expressed in all Expressed in all ovary: 657.3 FIBP FGFIBP ENSG00000172500 Fibroblast growth factor (acidic) intracellular binding protein 11 65883741-65888539 Predicted intracellular proteins Evidence at protein level HPA011729 Approved Supported Nuclear speckles Liver cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all testis: 78.6 FIG4 ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3 ENSG00000112367 FIG4 phosphoinositide 5-phosphatase 6 109691312-109825428 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017823, HPA068859 Approved Approved Vesicles
Lipid droplets Liver cancer:4.73e-4 (unfavourable), Breast cancer:5.91e-4 (unfavourable), Renal cancer:8.19e-4 (favourable), Colorectal cancer:8.42e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 32.6 FIP1L1 DKFZp586K0717, FIP1 ENSG00000145216 Factor interacting with PAPOLA and CPSF1 4 53377643-53460861 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037475, HPA058202 Supported Validated Nucleoplasm Liver cancer:1.51e-4 (unfavourable) Expressed in all Expressed in all testis: 68.7 FIS1 CGI-135, Fis1, H_NH0132A01.6, TTC11 ENSG00000214253 Fission, mitochondrial 1 7 101239458-101252316 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017430 Approved Validated Mitochondria Renal cancer:1.08e-7 (favourable) Expressed in all Expressed in all thyroid gland: 269.1 FIZ1 FLJ14768, ZNF798 ENSG00000179943 FLT3-interacting zinc finger 1 19 55591371-55601970 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA074026 Approved Nucleus Urothelial cancer:2.02e-4 (favourable), Pancreatic cancer:8.42e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 20.6 FKBP15 FKBP133, KIAA0674, PPP1R76, WAFL ENSG00000119321 FK506 binding protein 15, 133kDa 9 113161006-113221361 Predicted intracellular proteins Evidence at protein level HPA007979 Approved Approved Nucleoli
Cytosol Testis cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.5 FKBP1A FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE ENSG00000088832 FK506 binding protein 1A, 12kDa 20 1368978-1393172 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004639, HPA051798, HPA057830 Uncertain Approved Microtubules Liver cancer:3.44e-7 (unfavourable), Renal cancer:6.69e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 368.4 FKBP2 FKBP-13, PPIase ENSG00000173486 FK506 binding protein 2, 13kDa 11 64241003-64244132 Enzymes, Predicted secreted proteins Evidence at protein level CAB025561, HPA049405 Supported Approved Plasma membrane Expressed in all Expressed in all epididymis: 392.9 FKBP3 FKBP-25, PPIase ENSG00000100442 FK506 binding protein 3, 25kDa 14 45115600-45135319 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000864, CAB012232, CAB012520 Supported Supported Cytosol Expressed in all Expressed in all skeletal muscle: 143.3 FKBP4 FKBP52, FKBP59 ENSG00000004478 FK506 binding protein 4, 59kDa 12 2794953-2805423 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006148, CAB017441, HPA062857 Supported Validated Nucleoplasm
Cytosol Liver cancer:6.12e-5 (unfavourable), Lung cancer:1.44e-4 (unfavourable), Endometrial cancer:7.65e-4 (unfavourable) Expressed in all Expressed in all testis: 107.6 FKBP5 FKBP51, FKBP54, P54, PPIase, Ptg-10 ENSG00000096060 FK506 binding protein 5 6 35573585-35728583 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009315, HPA031092, HPA031093, HPA031095 Supported Validated Nucleoplasm Expressed in all Expressed in all adipose tissue: 414.0 FKBP8 FKBP38, FKBPr38 ENSG00000105701 FK506 binding protein 8, 38kDa 19 18531751-18544077 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025346, HPA045177 Supported Supported Endoplasmic reticulum
Mitochondria
Cytosol Colorectal cancer:1.24e-4 (unfavourable), Pancreatic cancer:7.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 355.7 FKBP9 FKBP60, FKBP63 ENSG00000122642 FK506 binding protein 9, 63 kDa 7 32957404-33006931 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012595, HPA055256 Approved Approved Golgi apparatus
Vesicles
Mitochondria Urothelial cancer:7.02e-6 (unfavourable), Head and neck cancer:2.02e-4 (unfavourable), Cervical cancer:4.22e-4 (unfavourable), Glioma:8.06e-4 (unfavourable), Liver cancer:8.69e-4 (unfavourable) Expressed in all Expressed in all placenta: 109.6 FKRP LGMD2I, MDC1C ENSG00000181027 Fukutin related protein 19 46746046-46776988 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043115, HPA060454 Approved Approved Nucleus
Golgi apparatus
Cytosol Pancreatic cancer:8.98e-4 (favourable) Expressed in all Expressed in all placenta: 14.8 FKTN FCMD, LGMD2M ENSG00000106692 Fukutin 9 105558130-105641118 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA012820 Approved Urothelial cancer:3.02e-4 (unfavourable), Liver cancer:9.42e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 17.0 FLAD1 FAD1, PP591 ENSG00000160688 Flavin adenine dinucleotide synthetase 1 1 154983338-154993111 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028476, HPA028486, HPA028563 Approved Supported Plasma membrane
Cytosol Renal cancer:2.55e-6 (unfavourable), Liver cancer:3.04e-4 (unfavourable) Expressed in all Expressed in all skin: 28.6 FLCN BHD, MGC17998, MGC23445 ENSG00000154803 Folliculin 17 17212212-17237188 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015158, HPA028760 Supported Supported Plasma membrane
Cytosol Pancreatic cancer:4.49e-4 (favourable) Expressed in all Expressed in all endometrium: 30.7 FLII FLI, Fli1, FLIL, MGC39265 ENSG00000177731 Flightless I actin binding protein 17 18244836-18258916 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007084, HPA008903, CAB016132 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all Expressed in all skeletal muscle: 82.5 FLNA ABP-280, FLN, FLN1, OPD1, OPD2 ENSG00000196924 Filamin A, alpha X 154348524-154374638 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000356, HPA000368, HPA001016, HPA001115, HPA002925 Supported Approved Validated Plasma membrane
Actin filaments
Cytosol Renal cancer:1.54e-6 (unfavourable), Urothelial cancer:3.88e-4 (unfavourable), Colorectal cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 1037.9 FLNB ABP-278, FH1, FLN1L, LRS1, TABP, TAP ENSG00000136068 Filamin B, beta 3 58008400-58172251 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004747, HPA004886, CAB019322 Supported Supported Golgi apparatus
Plasma membrane
Actin filaments
Cytosol Renal cancer:3.45e-6 (favourable), Pancreatic cancer:8.45e-5 (unfavourable) Expressed in all Expressed in all prostate: 161.4 FLOT1 ENSG00000137312 Flotillin 1 6 30727709-30742733 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001393, CAB007766 Supported Approved Golgi apparatus
Vesicles
Plasma membrane Renal cancer:1.49e-4 (unfavourable), Ovarian cancer:3.06e-4 (favourable), Colorectal cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 18.8 FLOT2 ECS-1, ECS1, ESA, ESA1, M17S1 ENSG00000132589 Flotillin 2 17 28879335-28897679 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001396, CAB004395 Supported Expressed in all Expressed in all spleen: 95.3 FLYWCH1 DKFZp761A132 ENSG00000059122 FLYWCH-type zinc finger 1 16 2911937-2951208 Predicted intracellular proteins Evidence at protein level HPA040753, HPA041001 Approved Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all parathyroid gland: 30.0 FLYWCH2 ENSG00000162076 FLYWCH family member 2 16 2883186-2899382 Predicted intracellular proteins Evidence at protein level HPA041354 Uncertain Approved Nucleus Pancreatic cancer:1.87e-5 (favourable), Cervical cancer:9.38e-4 (favourable) Expressed in all Expressed in all spleen: 35.8 FMNL1 C17orf1, C17orf1B, FMNL ENSG00000184922 Formin-like 1 17 45221444-45247320 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008129, HPA028288 Supported Approved Cytosol Renal cancer:4.23e-8 (unfavourable) Expressed in all Expressed in all bone marrow: 175.4 FMR1 FMRP, FRAXA, MGC87458, POF, POF1 ENSG00000102081 Fragile X mental retardation 1 X 147911951-147951125 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB012444, HPA050118, HPA056084 Approved Validated Cytosol Endometrial cancer:1.32e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 54.5 FN3K ENSG00000167363 Fructosamine 3 kinase 17 82735575-82751197 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059151, HPA061358 Supported Approved Mitochondria Renal cancer:1.39e-6 (favourable), Endometrial cancer:1.10e-4 (favourable), Pancreatic cancer:2.40e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 57.1 FN3KRP FLJ12171, FN3KL ENSG00000141560 Fructosamine 3 kinase related protein 17 82716683-82730328 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056172, HPA065831 Approved Approved Nucleoplasm Glioma:5.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 49.0 FNBP1 FBP17, KIAA0554 ENSG00000187239 Formin binding protein 1 9 129887187-130043194 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019691, HPA022119 Supported Renal cancer:8.45e-5 (unfavourable) Expressed in all Expressed in all lymph node: 91.9 FNBP1L C1orf39, FLJ20275, TOCA1 ENSG00000137942 Formin binding protein 1-like 1 93448131-93554661 Predicted intracellular proteins Evidence at protein level HPA065273 Approved Approved Vesicles Renal cancer:4.72e-7 (favourable), Liver cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 53.6 FNBP4 KIAA1014 ENSG00000109920 Formin binding protein 4 11 47716517-47767443 Predicted intracellular proteins Evidence at protein level HPA039485, HPA040029 Supported Validated Nuclear speckles Renal cancer:1.91e-8 (unfavourable), Urothelial cancer:7.23e-5 (favourable), Liver cancer:7.33e-5 (unfavourable), Melanoma:2.50e-4 (unfavourable), Prostate cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all spleen: 48.9 FNDC3A bA203I16.5, FNDC3, KIAA0970 ENSG00000102531 Fibronectin type III domain containing 3A 13 48975912-49209779 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008927, HPA012825 Approved Approved Endoplasmic reticulum Renal cancer:4.25e-4 (favourable) Expressed in all Expressed in all thyroid gland: 85.5 FNDC3B DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421 ENSG00000075420 Fibronectin type III domain containing 3B 3 172039628-172401665 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007859 Uncertain Approved Endoplasmic reticulum Renal cancer:5.65e-7 (unfavourable), Cervical cancer:2.41e-5 (unfavourable), Pancreatic cancer:9.06e-5 (unfavourable), Liver cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all placenta: 76.8 FNIP1 KIAA1961 ENSG00000217128 Folliculin interacting protein 1 5 131641714-131797063 Predicted intracellular proteins Evidence at protein level HPA068099, HPA071213 Approved Expressed in all Expressed in all testis: 28.4 FNIP2 FNIPL, KIAA1450, MAPO1 ENSG00000052795 Folliculin interacting protein 2 4 158769138-158908049 Predicted intracellular proteins Evidence at protein level HPA042779 Approved Renal cancer:3.96e-11 (favourable) Expressed in all Expressed in all kidney: 50.8 FNTA FPTA, PGGT1A, PTAR2 ENSG00000168522 Farnesyltransferase, CAAX box, alpha 8 43034194-43085788 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010149, HPA018830 Approved Approved Cytosol Renal cancer:2.94e-12 (unfavourable) Expressed in all Expressed in all placenta: 62.5 FNTB FPTB ENSG00000257365 Farnesyltransferase, CAAX box, beta 14 64986720-65062652 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062743 Approved Approved Centrosome Liver cancer:6.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 17.7 FO538757.2 ENSG00000279457 1 184923-200322 Predicted intracellular proteins Evidence at protein level HPA002689 Uncertain Approved Vesicles Pancreatic cancer:6.41e-7 (favourable), Renal cancer:2.00e-6 (unfavourable) Expressed in all Expressed in all skin: 30.5 FOCAD FLJ20375, KIAA1797 ENSG00000188352 Focadhesin 9 20658309-20995955 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055015 Uncertain Uncertain Mitochondria Renal cancer:3.09e-8 (favourable), Liver cancer:4.41e-5 (unfavourable), Colorectal cancer:3.25e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.0 FOLR2 ENSG00000165457 Folate receptor 2 (fetal) 11 72216601-72221950 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Thyroid cancer:8.41e-4 (favourable), Colorectal cancer:8.42e-4 (unfavourable) Expressed in all Expressed in all placenta: 233.7 FOPNL C16orf63, DKFZp686N1651, FLJ31153, FOR20, PHSECRG2 ENSG00000133393 FGFR1OP N-terminal like 16 15865720-15888625 Predicted intracellular proteins Evidence at protein level HPA040599 Supported Supported Centrosome Expressed in all Expressed in all thyroid gland: 53.7 FOS AP-1, c-fos ENSG00000170345 FBJ murine osteosarcoma viral oncogene homolog 14 75278774-75282230 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018531 Approved Supported Nucleoplasm Prostate cancer:7.81e-4 (favourable) Expressed in all Expressed in all fallopian tube: 1834.8 FOSL2 FLJ23306, FRA2 ENSG00000075426 FOS-like antigen 2 2 28392448-28417312 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004817, CAB013460, HPA061417 Supported Validated Nucleus Expressed in all Expressed in all adrenal gland: 226.0 FOXJ2 FHX ENSG00000065970 Forkhead box J2 12 8032703-8055503 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008723 Approved Supported Nucleus
Nucleoli fibrillar center Renal cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.5 FOXJ3 KIAA1041 ENSG00000198815 Forkhead box J3 1 42176539-42335877 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067284 Approved Nucleoplasm
Nuclear speckles
Vesicles Renal cancer:4.51e-7 (unfavourable), Liver cancer:5.17e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.5 FOXK2 ILF, ILF1 ENSG00000141568 Forkhead box K2 17 82519713-82644662 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027523 Approved Supported Nucleoplasm
Vesicles Liver cancer:1.24e-6 (unfavourable) Expressed in all Expressed in all testis: 64.8 FOXN2 HTLF ENSG00000170802 Forkhead box N2 2 48314637-48379294 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003485 Supported Supported Nucleus
Vesicles Renal cancer:2.81e-5 (unfavourable), Glioma:5.14e-4 (favourable) Expressed in all Expressed in all bone marrow: 36.5 FOXN3 C14orf116, CHES1 ENSG00000053254 Forkhead box N3 14 89124871-89619149 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059209 Approved Approved Nucleus
Plasma membrane
Cytokinetic bridge Renal cancer:9.58e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 109.4 FOXO1 FKH1, FKHR, FOXO1A ENSG00000150907 Forkhead box O1 13 40555667-40666597 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001252, CAB022326 Approved Approved Supported Nucleoplasm
Cytosol Renal cancer:1.33e-5 (favourable), Liver cancer:3.74e-4 (favourable) Expressed in all Expressed in all ovary: 80.5 FOXO3 AF6q21, FKHRL1, FOXO2, FOXO3A ENSG00000118689 Forkhead box O3 6 108559835-108684774 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004074, HPA063104 Supported Validated Nucleus Expressed in all Expressed in all ovary: 54.9 FOXO4 AFX1, MLLT7 ENSG00000184481 Forkhead box O4 X 71096197-71103535 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level HPA039560, HPA040232 Approved Supported Nuclear speckles
Cytosol Renal cancer:3.46e-4 (favourable), Head and neck cancer:4.61e-4 (favourable) Expressed in all Expressed in all placenta: 171.9 FOXP1 12CC4, hFKH1B, HSPC215, QRF1 ENSG00000114861 Forkhead box P1 3 70954693-71583989 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003876, CAB011501 Supported Validated Nucleoplasm Expressed in all Expressed in all ovary: 39.5 FOXP4 FLJ40908 ENSG00000137166 Forkhead box P4 6 41546426-41602384 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007176 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:1.17e-6 (unfavourable), Liver cancer:9.72e-4 (unfavourable) Expressed in all Expressed in all stomach: 37.2 FOXRED1 H17 ENSG00000110074 FAD-dependent oxidoreductase domain containing 1 11 126269055-126278131 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039620, HPA046192 Uncertain Supported Mitochondria Renal cancer:2.01e-6 (favourable), Breast cancer:7.36e-4 (unfavourable) Expressed in all Expressed in all liver: 19.0 FPGS ENSG00000136877 Folylpolyglutamate synthase 9 127794597-127814327 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA050488 Approved Endometrial cancer:9.08e-4 (favourable) Expressed in all Expressed in all ovary: 26.1 FPGT GFPP ENSG00000254685 Fucose-1-phosphate guanylyltransferase 1 74198212-74234086 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA072331 Uncertain Vesicles Liver cancer:2.30e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 32.7 FRA10AC1 C10orf4 ENSG00000148690 Fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 10 93667883-93702572 Predicted intracellular proteins Evidence at protein level HPA039204 Approved Expressed in all Expressed in all cerebral cortex: 21.4 FRAT2 ENSG00000181274 Frequently rearranged in advanced T-cell lymphomas 2 10 97332497-97334709 Predicted intracellular proteins Evidence at transcript level HPA049763 Uncertain Approved Nucleus
Mitochondria Renal cancer:2.55e-4 (favourable), Liver cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all duodenum: 26.2 FRG1 FRG1A, FSG1 ENSG00000109536 FSHD region gene 1 4 189940788-189963204 Disease related genes, Predicted intracellular proteins Evidence at protein level Stomach cancer:9.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.6 FRMD4A bA295P9.4, FLJ10210, FRMD4, KIAA1294 ENSG00000151474 FERM domain containing 4A 10 13643706-14462142 Predicted intracellular proteins Evidence at protein level HPA038449 Uncertain Approved Nucleus
Golgi apparatus Head and neck cancer:2.63e-5 (favourable) Expressed in all Expressed in all spleen: 38.7 FRMD8 FKSG44, FLJ90369 ENSG00000126391 FERM domain containing 8 11 65386599-65413525 Predicted intracellular proteins Evidence at protein level HPA002861, HPA005506 Approved Approved Nucleus
Nucleoli
Cytosol Liver cancer:9.94e-5 (unfavourable) Expressed in all Expressed in all skin: 25.0 FRS2 FRS2A, FRS2alpha, SNT-1, SNT1 ENSG00000166225 Fibroblast growth factor receptor substrate 2 12 69470349-69579789 Predicted intracellular proteins Evidence at protein level HPA038323 Approved Cell Junctions Expressed in all Expressed in all parathyroid gland: 27.0 FRY 13CDNA73, bA37E23.1, C13orf14, CG003 ENSG00000073910 Furry homolog (Drosophila) 13 32031300-32299122 Predicted intracellular proteins Evidence at protein level HPA041635 Approved Renal cancer:9.60e-4 (favourable) Mixed Expressed in all heart muscle: 32.0 FRYL AF4p12, DKFZp686E205, KIAA0826 ENSG00000075539 FRY-like 4 48497361-48780322 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031106, HPA031107 Supported Approved Microtubules
Cytokinetic bridge
Cytosol Expressed in all Expressed in all parathyroid gland: 50.3 FSTL1 FRP, FSL1 ENSG00000163430 Follistatin-like 1 3 120392293-120451253 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035251 Approved Approved Vesicles
Cytosol Renal cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all placenta: 651.3 FSTL3 FLRG, FSRP ENSG00000070404 Follistatin-like 3 (secreted glycoprotein) 19 676365-683399 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB024899, HPA045378 Approved Approved Nucleoplasm Lung cancer:4.61e-7 (unfavourable), Ovarian cancer:1.65e-4 (unfavourable), Colorectal cancer:3.01e-4 (unfavourable), Endometrial cancer:3.03e-4 (unfavourable) Expressed in all Expressed in all placenta: 259.7 FTH1 FHC, FTH, FTHL6, PIG15, PLIF ENSG00000167996 Ferritin, heavy polypeptide 1 11 61959718-61967660 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008623 Approved Approved Microtubules Renal cancer:5.20e-5 (unfavourable), Head and neck cancer:7.56e-5 (unfavourable), Liver cancer:6.18e-4 (unfavourable) Expressed in all Expressed in all appendix: 5085.0 FTL MGC71996, NBIA3 ENSG00000087086 Ferritin, light polypeptide 19 48965301-48966878 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB020769, HPA041602 Supported Approved Cytosol Renal cancer:4.40e-5 (unfavourable) Expressed in all Expressed in all lung: 8051.2 FTO ALKBH9, KIAA1752, MGC5149 ENSG00000140718 Fat mass and obesity associated 16 53703963-54121941 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB017123, HPA041086 Supported Approved Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 75.4 FTSJ1 CDLIV, JM23, MRX44, MRX9, SPB1, TRM7, TRMT7 ENSG00000068438 FtsJ RNA methyltransferase homolog 1 (E. coli) X 48476021-48486364 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002718 Approved Approved Cytosol Renal cancer:5.24e-10 (unfavourable), Liver cancer:1.74e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 24.5 FTSJ2 FJH1, MRM2, RRMJ2 ENSG00000122687 FtsJ RNA methyltransferase homolog 2 (E. coli) 7 2234231-2242198 Predicted intracellular proteins Evidence at protein level HPA019826, HPA049622 Uncertain Liver cancer:5.21e-6 (unfavourable) Expressed in all Expressed in all lymph node: 19.9 FTSJ3 SPB1 ENSG00000108592 FtsJ homolog 3 (E. coli) 17 63819433-63830012 Predicted intracellular proteins Evidence at protein level HPA055544, HPA062628 Supported Validated Nucleoli Liver cancer:1.44e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.4 FUBP1 FBP, FUBP ENSG00000162613 Far upstream element (FUSE) binding protein 1 1 77944055-77979110 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006149 Supported Validated Nucleoplasm Liver cancer:9.83e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 68.1 FUBP3 FBP3 ENSG00000107164 Far upstream element (FUSE) binding protein 3 9 130578965-130638352 Predicted intracellular proteins Evidence at protein level HPA047658, HPA058392 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:4.39e-5 (favourable), Lung cancer:2.38e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 71.5 FUCA1 ENSG00000179163 Fucosidase, alpha-L- 1, tissue 1 23845077-23868294 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA046542, HPA056371 Supported Renal cancer:5.70e-13 (favourable), Endometrial cancer:2.45e-4 (favourable) Expressed in all Expressed in all lymph node: 188.2 FUCA2 dJ20N2.5, MGC1314 ENSG00000001036 Fucosidase, alpha-L- 2, plasma 6 143494811-143511690 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031659, HPA031660, HPA031661 Uncertain Liver cancer:2.70e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 152.0 FUK FLJ39408 ENSG00000157353 Fucokinase 16 70454421-70480274 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041971 Approved Approved Vesicles Urothelial cancer:8.38e-4 (favourable), Renal cancer:8.91e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 14.2 FUNDC1 MGC51029 ENSG00000069509 FUN14 domain containing 1 X 44523639-44543001 Predicted intracellular proteins Evidence at protein level HPA038773 Uncertain Urothelial cancer:2.58e-4 (favourable), Testis cancer:8.35e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 30.7 FUNDC2 DC44, HCBP6 ENSG00000165775 FUN14 domain containing 2 X 155025980-155060303 Predicted intracellular proteins Evidence at protein level HPA059129 Approved Liver cancer:3.78e-5 (unfavourable), Endometrial cancer:7.26e-4 (unfavourable), Cervical cancer:9.20e-4 (favourable) Expressed in all Expressed in all ovary: 7.8 FURIN FUR, PACE, PCSK3, SPC1 ENSG00000140564 Furin (paired basic amino acid cleaving enzyme) 15 90868592-90883458 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB009499 Approved Supported Nucleoplasm
Golgi apparatus Lung cancer:1.58e-4 (unfavourable) Expressed in all Expressed in all salivary gland: 93.2 FUS ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS ENSG00000089280 FUS RNA binding protein 16 31180110-31194871 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008784, CAB033036, CAB058691 Supported Validated Nucleoplasm Liver cancer:4.38e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 146.2 FUZ FLJ22688, Fy ENSG00000010361 Fuzzy planar cell polarity protein 19 49806869-49817376 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041779, HPA042196 Uncertain Approved Cytosol Renal cancer:1.50e-5 (favourable) Expressed in all Expressed in all testis: 52.6 FXN CyaY, FA, FARR, FRDA, X25 ENSG00000165060 Frataxin 9 69035259-69100178 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB022164, HPA068304 Supported Supported Mitochondria
Cytosol Expressed in all Expressed in all parathyroid gland: 33.5 FXR1 ENSG00000114416 Fragile X mental retardation, autosomal homolog 1 3 180868141-180982753 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018246, HPA055475 Approved Validated Cytosol Renal cancer:2.19e-5 (unfavourable), Liver cancer:2.70e-4 (unfavourable), Endometrial cancer:5.96e-4 (unfavourable), Pancreatic cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 276.6 FXR2 FMR1L2 ENSG00000129245 Fragile X mental retardation, autosomal homolog 2 17 7591230-7614871 Predicted intracellular proteins Evidence at protein level CAB011205, HPA022997 Supported Supported Cytosol Pancreatic cancer:3.49e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 43.9 FXYD1 PLM ENSG00000266964 FXYD domain containing ion transport regulator 1 19 35138808-35143109 Predicted membrane proteins Evidence at protein level HPA026873 Approved Nucleus
Nucleoli
Cytosol Renal cancer:7.59e-8 (unfavourable), Glioma:9.67e-4 (unfavourable) Tissue enhanced Expressed in all skeletal muscle: 469.2 FXYD5 OIT2 ENSG00000089327 FXYD domain containing ion transport regulator 5 19 35154730-35169883 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA010817 Uncertain Approved Endoplasmic reticulum Renal cancer:3.71e-9 (unfavourable) Expressed in all Expressed in all spleen: 241.4 FXYD6 ENSG00000137726 FXYD domain containing ion transport regulator 6 11 117836976-117877486 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA041334, HPA042284 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:1.05e-5 (unfavourable), Renal cancer:4.38e-5 (favourable), Urothelial cancer:1.60e-4 (unfavourable), Liver cancer:5.87e-4 (favourable), Pancreatic cancer:5.97e-4 (favourable) Tissue enriched Expressed in all cerebral cortex: 698.7 FYCO1 FLJ13335, ZFYVE7 ENSG00000163820 FYVE and coiled-coil domain containing 1 3 45917899-45995824 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035526, HPA057966 Uncertain Validated Vesicles Renal cancer:3.33e-11 (favourable) Expressed in all Expressed in all skeletal muscle: 91.9 FYN MGC45350, SLK, SYN ENSG00000010810 FYN proto-oncogene, Src family tyrosine kinase 6 111660332-111873452 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005034, CAB018387, HPA023887, HPA063770 Approved Validated Plasma membrane
Cytosol Renal cancer:1.43e-4 (unfavourable), Liver cancer:1.84e-4 (favourable), Pancreatic cancer:4.78e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 166.6 FYTTD1 DKFZp761B1514, UIF ENSG00000122068 Forty-two-three domain containing 1 3 197737179-197787596 Predicted intracellular proteins Evidence at protein level HPA054474 Supported Nuclear speckles Endometrial cancer:3.08e-4 (unfavourable) Expressed in all Expressed in all testis: 76.3 FZR1 CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242 ENSG00000105325 Fizzy/cell division cycle 20 related 1 19 3506273-3538330 Predicted intracellular proteins Evidence at protein level HPA043536 Approved Supported Nucleoplasm
Nuclear membrane Cervical cancer:1.75e-4 (favourable), Endometrial cancer:2.57e-4 (favourable) Expressed in all Expressed in all testis: 33.1 G3BP1 G3BP, HDH-VIII ENSG00000145907 GTPase activating protein (SH3 domain) binding protein 1 5 151771045-151812785 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004052, CAB037068 Supported Validated Cytosol Renal cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all testis: 90.7 G3BP2 KIAA0660 ENSG00000138757 GTPase activating protein (SH3 domain) binding protein 2 4 75642782-75724525 Predicted intracellular proteins Evidence at protein level HPA018304, HPA018425 Supported Validated Cytosol Renal cancer:6.65e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 179.1 G6PC3 UGRP ENSG00000141349 Glucose 6 phosphatase, catalytic, 3 17 44070735-44076344 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067052 Supported Endoplasmic reticulum Endometrial cancer:1.11e-4 (favourable), Liver cancer:9.61e-4 (unfavourable) Expressed in all Expressed in all epididymis: 82.8 G6PD G6PD1 ENSG00000160211 Glucose-6-phosphate dehydrogenase X 154531391-154547572 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA000247, HPA000834 Supported Approved Vesicles
Microtubule organizing center
Cytosol Liver cancer:9.45e-13 (unfavourable) Expressed in all Expressed in all testis: 107.0 GAA ENSG00000171298 Glucosidase, alpha; acid 17 80101556-80119879 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026970, HPA029126 Supported Colorectal cancer:7.66e-4 (unfavourable) Expressed in all Expressed in all placenta: 69.4 GAB1 ENSG00000109458 GRB2-associated binding protein 1 4 143336762-143474568 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA049599 Approved Vesicles Renal cancer:3.91e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 32.3 GAB2 KIAA0571 ENSG00000033327 GRB2-associated binding protein 2 11 78215297-78418348 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA000271, HPA001368, CAB022159 Approved Supported Plasma membrane Renal cancer:9.32e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 35.6 GABARAP ATG8A, MM46 ENSG00000170296 GABA(A) receptor-associated protein 17 7240014-7242770 Predicted intracellular proteins, Transporters Evidence at protein level HPA065883 Approved Vesicles Pancreatic cancer:9.52e-5 (favourable) Expressed in all Expressed in all epididymis: 750.2 GABARAPL1 APG8L, ATG8B, ATG8L, gec1 ENSG00000139112 GABA(A) receptor-associated protein like 1 12 10212458-10223130 Predicted intracellular proteins Evidence at protein level HPA051386, HPA065883 Approved Approved Vesicles Renal cancer:8.19e-8 (favourable), Liver cancer:2.36e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 433.4 GABARAPL2 ATG8, ATG8C, GATE-16, GATE16, GEF2 ENSG00000034713 GABA(A) receptor-associated protein like 2 16 75566351-75577881 Predicted intracellular proteins Evidence at protein level HPA036726 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:5.95e-8 (favourable), Head and neck cancer:7.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 320.2 GABPA E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A ENSG00000154727 GA binding protein transcription factor, alpha subunit 60kDa 21 25734570-25772460 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003258, CAB004411, HPA028791 Supported Validated Nucleoplasm Renal cancer:3.97e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 37.9 GABPB1 E4TF1-47, GABPB, GABPB2 ENSG00000104064 GA binding protein transcription factor, beta subunit 1 15 50275392-50355408 Predicted intracellular proteins Evidence at protein level HPA019653, HPA067444 Supported Supported Nucleoplasm
Cytoplasmic bodies Renal cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all testis: 28.7 GABRP ENSG00000094755 Gamma-aminobutyric acid (GABA) A receptor, pi 5 170763350-170814047 FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB014883 Uncertain Cervical cancer:3.37e-4 (favourable) Mixed Expressed in all breast: 186.6 GADD45A DDIT1, GADD45 ENSG00000116717 Growth arrest and DNA-damage-inducible, alpha 1 67685061-67688338 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA053420 Supported Nuclear speckles Renal cancer:8.06e-6 (favourable) Expressed in all Expressed in all thyroid gland: 91.1 GADD45B DKFZP566B133, GADD45BETA, MYD118 ENSG00000099860 Growth arrest and DNA-damage-inducible, beta 19 2476122-2478259 Predicted intracellular proteins Evidence at protein level HPA029816 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all bone marrow: 218.5 GADD45GIP1 CKBBP2, CKbetaBP2, CRIF1, MGC4667, MGC4758, PLINP-1, Plinp1, PRG6 ENSG00000179271 Growth arrest and DNA-damage-inducible, gamma interacting protein 1 19 12953119-12957236 Predicted intracellular proteins Evidence at protein level HPA055205, HPA065048 Supported Supported Mitochondria Expressed in all Expressed in all cerebral cortex: 29.7 GAK DNAJC26 ENSG00000178950 Cyclin G associated kinase 4 849276-932373 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027405, HPA027459, HPA027463 Approved Validated Golgi apparatus
Vesicles Renal cancer:1.70e-6 (favourable), Urothelial cancer:7.41e-4 (favourable) Expressed in all Expressed in all duodenum: 52.9 GALC ENSG00000054983 Galactosylceramidase 14 87837820-87993665 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB022196 Approved Expressed in all Expressed in all testis: 45.4 GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase 1 23795599-23800804 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007340 Approved Approved Nucleus
Cytosol Thyroid cancer:2.68e-4 (favourable) Expressed in all Expressed in all stomach: 113.6 GALK1 GALK ENSG00000108479 Galactokinase 1 17 75751594-75765711 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007094, HPA016960 Approved Approved Golgi apparatus
Cytosol Renal cancer:1.55e-6 (unfavourable), Urothelial cancer:1.62e-5 (unfavourable) Expressed in all Expressed in all duodenum: 23.8 GALK2 GK2 ENSG00000156958 Galactokinase 2 15 49155656-49367869 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043564, HPA048267 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.88e-5 (favourable), Endometrial cancer:7.31e-4 (favourable) Expressed in all Expressed in all kidney: 31.7 GALM ENSG00000143891 Galactose mutarotase (aldose 1-epimerase) 2 38665910-38741237 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035472, HPA035473 Supported Approved Nucleoplasm Renal cancer:9.06e-5 (favourable), Urothelial cancer:1.32e-4 (favourable) Expressed in all Expressed in all kidney: 117.1 GALNS GALNAC6S, GAS ENSG00000141012 Galactosamine (N-acetyl)-6-sulfatase 16 88813734-88856970 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026404 Supported Approved Cytosol Liver cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all testis: 29.7 GALNT1 GalNAc-T1 ENSG00000141429 Polypeptide N-acetylgalactosaminyltransferase 1 18 35581117-35711834 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012628 Uncertain Expressed in all Expressed in all urinary bladder: 88.7 GALNT10 GalNAc-T10 ENSG00000164574 Polypeptide N-acetylgalactosaminyltransferase 10 5 154190730-154420984 Enzymes, Predicted secreted proteins Evidence at protein level HPA007525 Approved Approved Nucleoplasm
Golgi apparatus
Plasma membrane Endometrial cancer:3.33e-6 (favourable), Ovarian cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all ovary: 81.4 GALNT11 GalNAc-T11 ENSG00000178234 Polypeptide N-acetylgalactosaminyltransferase 11 7 152025674-152122347 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA039330 Uncertain Renal cancer:2.24e-6 (favourable), Glioma:8.42e-4 (unfavourable) Expressed in all Expressed in all kidney: 241.1 GALNT2 GalNAc-T2 ENSG00000143641 Polypeptide N-acetylgalactosaminyltransferase 2 1 230057990-230282124 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA011222 Supported Validated Golgi apparatus Renal cancer:2.79e-13 (unfavourable), Lung cancer:8.48e-8 (unfavourable), Cervical cancer:1.22e-6 (unfavourable) Expressed in all Expressed in all appendix,ovary: 48.5 GALT ENSG00000213930 Galactose-1-phosphate uridylyltransferase 9 34638133-34651035 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004868, HPA005729 Supported Approved Cytosol Renal cancer:6.25e-6 (favourable), Pancreatic cancer:3.11e-5 (favourable) Expressed in all Expressed in all liver: 25.8 GAMT PIG2, TP53I2 ENSG00000130005 Guanidinoacetate N-methyltransferase 19 1397084-1401570 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051806 Approved Stomach cancer:6.57e-4 (unfavourable) Tissue enriched Expressed in all skeletal muscle: 400.4 GANAB G2AN, GluII, KIAA0088 ENSG00000089597 Glucosidase, alpha; neutral AB 11 62624826-62646726 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026874, HPA061426 Supported Approved Nuclear membrane
Endoplasmic reticulum
Cytosol Liver cancer:1.27e-5 (unfavourable), Urothelial cancer:9.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 289.5 GANC ENSG00000214013 Glucosidase, alpha; neutral C 15 42273233-42356935 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA016949 Approved Approved Nucleoplasm
Actin filaments Lung cancer:9.76e-4 (favourable) Expressed in all Expressed in all lung: 42.6 GAPDH GAPD ENSG00000111640 Glyceraldehyde-3-phosphate dehydrogenase 12 6533927-6538374 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005197, CAB016392, HPA040067, HPA061280 Supported Validated Plasma membrane
Cytosol Renal cancer:6.25e-10 (unfavourable), Liver cancer:1.79e-6 (unfavourable) Expressed in all Expressed in all skeletal muscle: 9875.4 GAPVD1 DKFZP434C212, KIAA1521 ENSG00000165219 GTPase activating protein and VPS9 domains 1 9 125261794-125367207 Predicted intracellular proteins Evidence at protein level HPA029386, HPA029387 Uncertain Supported Cytosol Expressed in all Expressed in all testis: 49.0 GAR1 NOLA1 ENSG00000109534 GAR1 homolog, ribonucleoprotein 4 109815510-109824740 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059098 Supported Supported Nucleus
Nucleoli fibrillar center Liver cancer:2.64e-5 (unfavourable) Expressed in all Expressed in all breast: 22.8 GARS CMT2D, DSMAV, GlyRS, SMAD1 ENSG00000106105 Glycyl-tRNA synthetase 7 30594681-30634033 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA017896, HPA019097 Supported Supported Cytosol Renal cancer:1.70e-5 (unfavourable), Urothelial cancer:3.04e-5 (unfavourable), Liver cancer:8.95e-5 (unfavourable), Breast cancer:1.02e-4 (unfavourable), Endometrial cancer:8.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 94.3 GART PGFT, PRGS ENSG00000159131 Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 21 33503931-33543491 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002119, HPA005779 Approved Uncertain Nucleoplasm
Mitochondria
Cytosol Renal cancer:3.95e-6 (unfavourable), Head and neck cancer:5.05e-5 (unfavourable), Liver cancer:9.82e-5 (unfavourable), Pancreatic cancer:2.19e-4 (unfavourable) Expressed in all Expressed in all testis: 55.3 GAS2L1 GAR22 ENSG00000185340 Growth arrest-specific 2 like 1 22 29306582-29312785 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019858 Approved Approved Plasma membrane
Cell Junctions Renal cancer:8.44e-4 (favourable) Expressed in all Expressed in all testis: 32.2 GAS6 AXLLG, AXSF, DKFZp666G247, FLJ34709 ENSG00000183087 Growth arrest-specific 6 13 113820549-113864067 Predicted secreted proteins Evidence at protein level HPA008275, HPA056080 Approved Approved Microtubule organizing center
Cytosol Urothelial cancer:8.93e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 192.6 GATAD1 FLJ22489, ODAG, RG083M05.2 ENSG00000157259 GATA zinc finger domain containing 1 7 92447453-92458836 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006105, HPA072785 Supported Nucleus Expressed in all Expressed in all thyroid gland: 42.5 GATAD2A p66alpha ENSG00000167491 GATA zinc finger domain containing 2A 19 19385826-19508931 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006759, HPA024373 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 64.2 GATAD2B P66beta ENSG00000143614 GATA zinc finger domain containing 2B 1 153804725-153922975 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017015 Approved Validated Nucleoplasm Colorectal cancer:1.30e-4 (unfavourable), Renal cancer:3.08e-4 (unfavourable) Expressed in all Expressed in all testis: 16.0 GATC 15E1.2, FLJ37000, gatC ENSG00000257218 Glutamyl-tRNA(Gln) amidotransferase, subunit C 12 120446438-120463749 Predicted intracellular proteins Evidence at protein level Liver cancer:4.21e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.9 GBA GBA1, GLUC ENSG00000177628 Glucosidase, beta, acid 1 155234452-155244699 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006667, CAB037171, CAB037289 Supported Expressed in all Expressed in all parathyroid gland: 270.9 GBA2 AD035, DKFZp762K054, KIAA1605, SPG46 ENSG00000070610 Glucosidase, beta (bile acid) 2 9 35736866-35749228 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA024026 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.24e-11 (favourable), Pancreatic cancer:6.00e-4 (favourable), Urothelial cancer:6.60e-4 (favourable) Expressed in all Expressed in all small intestine: 65.5 GBAS NIPSNAP2 ENSG00000146729 Glioblastoma amplified sequence 7 55951793-56000181 Predicted intracellular proteins Evidence at protein level HPA063084 Supported Supported Mitochondria Renal cancer:3.02e-8 (favourable) Expressed in all Expressed in all skeletal muscle: 224.4 GBE1 ENSG00000114480 Glucan (1,4-alpha-), branching enzyme 1 3 81489699-81762161 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038073, HPA038074, HPA038075 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all adipose tissue: 79.3 GBF1 ARF1GEF, KIAA0248 ENSG00000107862 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 10 102245532-102382899 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037759, HPA037760 Uncertain Supported Golgi apparatus Expressed in all Expressed in all parathyroid gland: 58.1 GBP1 ENSG00000117228 Guanylate binding protein 1, interferon-inducible 1 89052319-89065360 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015450 Approved Renal cancer:5.12e-9 (unfavourable), Ovarian cancer:5.04e-4 (favourable), Colorectal cancer:8.32e-4 (favourable) Expressed in all Expressed in all appendix: 122.1 GBP2 ENSG00000162645 Guanylate binding protein 2, interferon-inducible 1 89106132-89150456 Predicted intracellular proteins Evidence at protein level HPA042682, CAB045975 Supported Supported Nucleoplasm
Actin filaments
Cytosol Renal cancer:2.14e-10 (unfavourable), Urothelial cancer:1.10e-5 (favourable), Pancreatic cancer:5.73e-5 (unfavourable), Breast cancer:7.57e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 192.3 GCAT KBL ENSG00000100116 Glycine C-acetyltransferase 22 37807905-37817176 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020460 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all pancreas: 28.9 GCC1 FLJ22035, GCC1P, GCC88, MGC20706 ENSG00000179562 GRIP and coiled-coil domain containing 1 7 127580618-127593611 Predicted intracellular proteins Evidence at protein level HPA019369, HPA021323 Supported Validated Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 18.7 GCDH ACAD5 ENSG00000105607 Glutaryl-CoA dehydrogenase 19 12891026-12914207 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043252, HPA048492 Supported Supported Mitochondria Renal cancer:6.79e-8 (favourable), Liver cancer:7.28e-5 (favourable), Lung cancer:3.35e-4 (favourable) Expressed in all Expressed in all liver: 42.8 GCFC2 C2orf3, DNABF, GCF, TCF9 ENSG00000005436 GC-rich sequence DNA-binding factor 2 2 75652000-75710989 Predicted intracellular proteins Evidence at protein level HPA077882 Supported Nucleoplasm
Cytosol Thyroid cancer:3.09e-4 (unfavourable), Endometrial cancer:9.59e-4 (unfavourable) Expressed in all Expressed in all endometrium: 17.5 GCHFR GFRP, HsT16933 ENSG00000137880 GTP cyclohydrolase I feedback regulator 15 40764020-40767710 Predicted intracellular proteins Evidence at protein level HPA046258 Approved Supported Nucleoplasm Lung cancer:5.62e-4 (favourable) Expressed in all Expressed in all small intestine: 63.7 GCLC GCS, GLCL, GLCLC ENSG00000001084 Glutamate-cysteine ligase, catalytic subunit 6 53497341-53616970 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009569, HPA036359, HPA036360 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.83e-6 (favourable), Thyroid cancer:8.24e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 81.9 GCLM GLCLR ENSG00000023909 Glutamate-cysteine ligase, modifier subunit 1 93885205-93909456 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB009568, HPA023696, CAB040554 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:9.83e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.1 GCN1 GCN1L, GCN1L1, KIAA0219 ENSG00000089154 GCN1 eIF2 alpha kinase activator homolog 12 120127203-120194710 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018799, HPA019648, HPA024367 Supported Validated Cytosol Liver cancer:1.87e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.8 GCSH ENSG00000140905 Glycine cleavage system protein H (aminomethyl carrier) 16 81081961-81096403 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041368 Approved Renal cancer:6.26e-6 (favourable) Expressed in all Expressed in all thyroid gland: 101.1 GDE1 MIR16 ENSG00000006007 Glycerophosphodiester phosphodiesterase 1 16 19501689-19522145 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA074747 Approved Nucleus
Nucleoli
Vesicles Renal cancer:3.12e-5 (favourable), Liver cancer:7.52e-5 (unfavourable), Colorectal cancer:3.12e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 68.8 GDI2 RABGDIB ENSG00000057608 GDP dissociation inhibitor 2 10 5765223-5842132 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049290, HPA057668 Supported Liver cancer:7.56e-7 (unfavourable), Glioma:7.00e-4 (favourable) Expressed in all Expressed in all lymph node: 244.2 GEMIN2 SIP1 ENSG00000092208 Gem (nuclear organelle) associated protein 2 14 39114223-39136973 Predicted intracellular proteins Evidence at protein level CAB015426, HPA046570, HPA057114 Supported Supported Nucleus
Nucleoli
Nuclear bodies Liver cancer:3.88e-6 (unfavourable) Expressed in all Expressed in all testis: 17.4 GEMIN4 DKFZP434B131, DKFZP434D174, HC56, HCAP1, HHRF-1, p97 ENSG00000179409 Gem (nuclear organelle) associated protein 4 17 744414-753999 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065699, HPA067891 Uncertain Supported Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 78.4 GEMIN5 ENSG00000082516 Gem (nuclear organelle) associated protein 5 5 154887416-154938209 Predicted intracellular proteins Evidence at protein level HPA037392, HPA037393 Uncertain Validated Nuclear bodies
Cytosol Endometrial cancer:6.23e-5 (unfavourable), Liver cancer:1.78e-4 (unfavourable), Renal cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.4 GEMIN7 FLJ13956 ENSG00000142252 Gem (nuclear organelle) associated protein 7 19 45079195-45091524 Predicted intracellular proteins Evidence at protein level HPA052075 Supported Nucleus
Cytosol Renal cancer:9.64e-11 (unfavourable), Liver cancer:5.86e-5 (unfavourable), Urothelial cancer:8.00e-4 (favourable) Expressed in all Expressed in all lymph node: 30.8 GEMIN8 FAM51A1, FLJ20514 ENSG00000046647 Gem (nuclear organelle) associated protein 8 X 14008279-14029893 Predicted intracellular proteins Evidence at protein level HPA028613 Uncertain Supported Nucleoplasm
Cytosol Urothelial cancer:7.73e-5 (favourable), Liver cancer:7.78e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 31.3 GET4 C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35 ENSG00000239857 Golgi to ER traffic protein 4 7 876552-896436 Predicted intracellular proteins Evidence at protein level HPA019765 Uncertain Supported Nucleoplasm
Nucleoli
Cytosol Expressed in all Expressed in all testis: 49.8 GFER ALR, ERV1, HERV1, HPO1, HPO2, HSS ENSG00000127554 Growth factor, augmenter of liver regeneration 16 1984207-1987749 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041227, HPA063553 Approved Validated Mitochondria
Cytosol Renal cancer:4.06e-4 (favourable) Expressed in all Expressed in all small intestine: 51.0 GFM1 EFGM, EGF1, GFM ENSG00000168827 G elongation factor, mitochondrial 1 3 158644278-158692575 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034764, HPA034765, HPA061405 Supported Approved Nucleus
Mitochondria Renal cancer:1.16e-7 (favourable), Pancreatic cancer:9.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 64.3 GFM2 EFG2, FLJ21661 ENSG00000164347 G elongation factor, mitochondrial 2 5 74721204-74767371 Predicted intracellular proteins Evidence at protein level HPA036863 Uncertain Renal cancer:1.33e-5 (favourable) Expressed in all Expressed in all fallopian tube: 36.3 GFOD2 FLJ23802, MGC11335 ENSG00000141098 Glucose-fructose oxidoreductase domain containing 2 16 67674531-67719421 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040939, HPA041112 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:5.95e-4 (favourable), Renal cancer:8.66e-4 (favourable) Expressed in all Expressed in all esophagus: 22.8 GFPT1 GFA, GFAT, GFAT1, GFPT ENSG00000198380 Glutamine--fructose-6-phosphate transaminase 1 2 69319769-69387254 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047240 Approved Nucleus
Nucleoli Colorectal cancer:7.13e-5 (favourable) Expressed in all Expressed in all thyroid gland: 81.6 GGA1 ENSG00000100083 Golgi-associated, gamma adaptin ear containing, ARF binding protein 1 22 37608475-37633564 Predicted intracellular proteins Evidence at protein level HPA048280, HPA051016 Supported Supported Nucleoplasm
Vesicles Pancreatic cancer:4.86e-4 (favourable), Liver cancer:6.29e-4 (unfavourable) Expressed in all Expressed in all testis: 199.1 GGA2 KIAA1080, VEAR ENSG00000103365 Golgi-associated, gamma adaptin ear containing, ARF binding protein 2 16 23463542-23521995 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034422, HPA043313, HPA063634 Approved Validated Golgi apparatus Cervical cancer:1.71e-5 (favourable), Renal cancer:3.91e-5 (favourable), Head and neck cancer:9.70e-5 (favourable), Lung cancer:1.68e-4 (favourable), Testis cancer:4.15e-4 (unfavourable) Expressed in all Expressed in all lymph node: 88.1 GGA3 KIAA0154 ENSG00000125447 Golgi-associated, gamma adaptin ear containing, ARF binding protein 3 17 75236599-75262363 Predicted intracellular proteins Evidence at protein level HPA022945, HPA024645 Approved Supported Golgi apparatus Liver cancer:2.77e-6 (unfavourable), Renal cancer:3.41e-4 (unfavourable), Endometrial cancer:8.26e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.1 GGCT C7orf24, CRF21, GCTG, Ggc, MGC3077 ENSG00000006625 Gamma-glutamylcyclotransferase 7 30496621-30504844 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020735, HPA029914 Approved Liver cancer:7.23e-4 (unfavourable), Breast cancer:7.68e-4 (unfavourable) Expressed in all Expressed in all epididymis: 123.9 GGCX VKCFD1 ENSG00000115486 Gamma-glutamyl carboxylase 2 85544723-85561547 Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA018284 Approved Endometrial cancer:1.82e-6 (unfavourable) Expressed in all Expressed in all liver: 61.2 GGNBP2 DIF-3, DIF3, FLJ21230, FLJ22561, LZK1, ZFP403, ZNF403 ENSG00000278311 Gametogenetin binding protein 2 17 36544888-36589848 Predicted intracellular proteins Evidence at protein level HPA018914, HPA073392 Approved Approved Endoplasmic reticulum Expressed in all Expressed in all testis: 55.4 GGPS1 GGPPS1 ENSG00000152904 Geranylgeranyl diphosphate synthase 1 1 235327350-235344532 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029472 Supported Liver cancer:6.69e-4 (unfavourable) Expressed in all Expressed in all testis: 89.7 GGT7 D20S101, dJ18C9.2, GGTL3, GGTL5 ENSG00000131067 Gamma-glutamyltransferase 7 20 34844720-34872860 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013204, HPA013339 Approved Approved Nucleus
Vesicles Endometrial cancer:1.26e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 50.1 GHDC LGP1 ENSG00000167925 GH3 domain containing 17 42188799-42194532 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA031650 Uncertain Renal cancer:2.00e-6 (favourable), Glioma:5.91e-5 (unfavourable), Endometrial cancer:3.21e-4 (favourable), Ovarian cancer:5.20e-4 (unfavourable) Expressed in all Expressed in all spleen: 29.8 GHITM DERP2, HSPC282, My021, PTD010, TMBIM5 ENSG00000165678 Growth hormone inducible transmembrane protein 10 84139440-84153555 Predicted membrane proteins Evidence at protein level HPA016464, HPA061664 Approved Supported Mitochondria Renal cancer:2.32e-10 (favourable), Head and neck cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all kidney: 349.8 GID4 C17orf39, VID24 ENSG00000141034 GID complex subunit 4 homolog 17 18039292-18068404 Predicted intracellular proteins Evidence at protein level HPA044348 Uncertain Approved Cytosol Expressed in all Expressed in all testis: 62.5 GID8 bA305P22.1, C20orf11, FLJ20602, TWA1 ENSG00000101193 GID complex subunit 8 20 62938119-62948475 Predicted intracellular proteins Evidence at protein level HPA049929, HPA055047 Approved Supported Nucleoplasm
Cell Junctions Renal cancer:3.22e-4 (favourable), Endometrial cancer:4.78e-4 (unfavourable) Expressed in all Expressed in all skin: 32.5 GIGYF1 GYF1, PERQ1 ENSG00000146830 GRB10 interacting GYF protein 1 7 100679507-100689448 Predicted intracellular proteins Evidence at protein level HPA020999, HPA023995 Approved Approved Vesicles
Microtubules Pancreatic cancer:1.35e-5 (favourable), Liver cancer:2.30e-4 (unfavourable), Head and neck cancer:7.42e-4 (favourable) Expressed in all Expressed in all endometrium: 35.7 GIGYF2 GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15 ENSG00000204120 GRB10 interacting GYF protein 2 2 232697299-232860575 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050899, HPA054612, HPA059918, HPA065064 Approved Validated Cytosol Renal cancer:6.97e-5 (favourable) Expressed in all Expressed in all testis: 85.3 GIMAP4 FLJ11110, HIMAP4, IAN1, IMAP4 ENSG00000133574 GTPase, IMAP family member 4 7 150567277-150573955 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019135, HPA019137, HPA027198 Supported Renal cancer:1.13e-4 (unfavourable), Endometrial cancer:7.63e-4 (favourable) Expressed in all Expressed in all spleen: 150.0 GIMAP5 HIMAP3, IAN4L1, IAN5 ENSG00000196329 GTPase, IMAP family member 5 7 150722253-150750033 Predicted membrane proteins Evidence at protein level Mixed Expressed in all lymph node: 81.6 GIMAP7 IAN7, MGC27027 ENSG00000179144 GTPase, IMAP family member 7 7 150514830-150521073 Predicted intracellular proteins Evidence at protein level HPA020266, HPA020268 Supported Approved Vesicles
Cytosol Liver cancer:8.98e-5 (favourable), Head and neck cancer:7.43e-4 (favourable) Expressed in all Expressed in all lymph node: 184.0 GINM1 C6orf72, dJ12G14.2 ENSG00000055211 Glycoprotein integral membrane 1 6 149566294-149591748 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017210, HPA041679 Approved Approved Nucleoli fibrillar center
Plasma membrane Expressed in all Expressed in all thyroid gland: 118.1 GIPC1 C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2 ENSG00000123159 GIPC PDZ domain containing family, member 1 19 14477760-14496149 Predicted intracellular proteins Evidence at protein level HPA043958, HPA061786 Approved Approved Nucleus
Plasma membrane
Cell Junctions Expressed in all Expressed in all esophagus: 104.4 GIT1 ENSG00000108262 G protein-coupled receptor kinase interacting ArfGAP 1 17 29573469-29594054 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004059, HPA004186 Approved Validated Focal adhesion sites
Cytosol Liver cancer:2.54e-6 (unfavourable) Expressed in all Expressed in all testis: 127.5 GIT2 KIAA0148 ENSG00000139436 G protein-coupled receptor kinase interacting ArfGAP 2 12 109929792-109996389 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004681 Approved Approved Microtubules Renal cancer:2.93e-4 (unfavourable) Expressed in all Expressed in all spleen: 48.6 GLA GALA ENSG00000102393 Galactosidase, alpha X 101397803-101407925 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA000237, HPA000966 Supported Liver cancer:5.62e-5 (unfavourable), Stomach cancer:6.16e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 58.5 GLB1 EBP, ELNR1 ENSG00000170266 Galactosidase, beta 1 3 32996608-33097230 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008382, HPA040610, HPA069503 Supported Supported Golgi apparatus
Vesicles Renal cancer:1.14e-5 (favourable) Expressed in all Expressed in all epididymis: 120.4 GLE1 GLE1L, hGLE1, LCCS1 ENSG00000119392 GLE1 RNA export mediator 9 128504700-128542288 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA041689, HPA043538, HPA061560 Supported Supported Nuclear membrane
Nucleoli Stomach cancer:7.04e-4 (favourable), Endometrial cancer:7.49e-4 (favourable) Expressed in all Expressed in all testis: 58.6 GLG1 CFR-1, ESL-1, MG-160 ENSG00000090863 Golgi glycoprotein 1 16 74447427-74607144 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010815 Supported Validated Golgi apparatus Renal cancer:1.56e-7 (favourable), Cervical cancer:1.99e-4 (unfavourable), Urothelial cancer:7.97e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 164.3 GLI4 HKR4, ZNF928 ENSG00000250571 GLI family zinc finger 4 8 143267433-143276931 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023131 Uncertain Approved Nucleus
Cytokinetic bridge Expressed in all Expressed in all spleen: 9.0 GLIPR2 C9orf19, GAPR-1 ENSG00000122694 GLI pathogenesis-related 2 9 36136536-36163913 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029478 Approved Uncertain Vesicles
Microtubules Renal cancer:6.54e-7 (unfavourable) Expressed in all Expressed in all lung: 93.8 GLMP C1orf85, MGC31963, NCU-G1 ENSG00000198715 Glycosylated lysosomal membrane protein 1 156290089-156295689 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029121 Uncertain Liver cancer:6.35e-5 (unfavourable) Expressed in all Expressed in all prostate: 94.9 GLO1 GLOD1 ENSG00000124767 Glyoxalase I 6 38675925-38703141 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB040541, CAB040542, HPA059791 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:5.21e-4 (unfavourable) Expressed in all Expressed in all prostate: 274.7 GLOD4 C17orf25, CGI-150, HC71 ENSG00000167699 Glyoxalase domain containing 4 17 757097-783390 Predicted intracellular proteins Evidence at protein level HPA021623, HPA023246, HPA023248 Supported Approved Nucleus
Nucleoli
Cytosol Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all duodenum: 83.4 GLRX GRX, GRX1 ENSG00000173221 Glutaredoxin (thioltransferase) 5 95751319-95823005 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008634, HPA046431, CAB069419 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all kidney: 217.3 GLRX2 bA101E13.1, GRX2 ENSG00000023572 Glutaredoxin 2 1 193096468-193106114 Predicted intracellular proteins Evidence at protein level HPA023087, HPA057224 Supported Validated Nucleoplasm Renal cancer:3.30e-7 (unfavourable) Expressed in all Expressed in all testis: 46.1 GLRX3 bA500G10.4, GLRX4, GRX3, GRX4, PICOT, TXNL2 ENSG00000108010 Glutaredoxin 3 10 130136399-130184521 Predicted intracellular proteins Evidence at protein level HPA028941 Approved Liver cancer:9.03e-6 (unfavourable), Renal cancer:9.24e-6 (unfavourable) Expressed in all Expressed in all testis: 118.7 GLRX5 C14orf87, GRX5, PR01238 ENSG00000182512 Glutaredoxin 5 14 95533503-95544724 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042465, HPA063716 Approved Supported Mitochondria Renal cancer:7.83e-10 (favourable), Ovarian cancer:1.08e-5 (favourable) Expressed in all Expressed in all bone marrow: 56.7 GLS GLS1, KIAA0838 ENSG00000115419 Glutaminase 2 190880827-190965552 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036223 Supported Supported Mitochondria Endometrial cancer:3.45e-4 (unfavourable) Expressed in all Expressed in all kidney: 330.7 GLT8D1 AD-017, FLJ14611 ENSG00000016864 Glycosyltransferase 8 domain containing 1 3 52694485-52706083 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010588 Approved Approved Mitochondria Endometrial cancer:2.76e-4 (favourable) Expressed in all Expressed in all testis: 116.6 GLTP ENSG00000139433 Glycolipid transfer protein 12 109850943-109880488 Predicted intracellular proteins Evidence at protein level HPA056461 Approved Supported Cytosol Thyroid cancer:4.17e-6 (favourable), Cervical cancer:2.01e-5 (favourable), Liver cancer:7.68e-4 (unfavourable) Expressed in all Expressed in all skin: 294.6 GLTSCR1L KIAA0240 ENSG00000112624 GLTSCR1-like 6 42746958-42868560 Predicted intracellular proteins Evidence at protein level HPA029390, HPA029391 Approved Supported Nucleoplasm Head and neck cancer:5.47e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.5 GLTSCR2 PICT-1 ENSG00000105373 Glioma tumor suppressor candidate region gene 2 19 47745522-47757058 Predicted intracellular proteins Evidence at protein level HPA018999, HPA049600 Approved Validated Nucleoli Endometrial cancer:2.35e-4 (favourable) Expressed in all Expressed in all ovary: 531.9 GLUD1 GDH, GLUD ENSG00000148672 Glutamate dehydrogenase 1 10 87050486-87094866 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA042492, HPA044839, HPA061369 Approved Supported Mitochondria Renal cancer:1.44e-6 (favourable), Pancreatic cancer:1.76e-5 (unfavourable), Glioma:5.08e-4 (favourable) Expressed in all Expressed in all liver: 457.5 GLUL GLNS ENSG00000135821 Glutamate-ammonia ligase 1 182381704-182392206 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007316, HPA007571, CAB008636 Approved Supported Mitochondria
Cytosol Breast cancer:4.81e-4 (favourable) Expressed in all Expressed in all adipose tissue: 1001.1 GLYR1 BM045, HIBDL, N-PAC, NP60 ENSG00000140632 Glyoxylate reductase 1 homolog (Arabidopsis) 16 4803203-4847342 Predicted intracellular proteins Evidence at protein level CAB017022, HPA048226, HPA050136 Supported Validated Nucleoplasm
Nuclear speckles Renal cancer:8.74e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 109.7 GM2A SAP-3 ENSG00000196743 GM2 ganglioside activator 5 151212150-151270440 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008063 Supported Liver cancer:1.77e-5 (unfavourable) Expressed in all Expressed in all skin: 89.8 GMCL1 BTBD13, FLJ13057, GCL1, SPATA29 ENSG00000087338 Germ cell-less, spermatogenesis associated 1 2 69829642-69881396 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039579 Approved Expressed in all Expressed in all testis: 39.2 GMEB2 KIAA1269, P79PIF, PIF79 ENSG00000101216 Glucocorticoid modulatory element binding protein 2 20 63587602-63627041 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009706, HPA067455 Approved Validated Nucleoplasm Expressed in all Expressed in all testis: 12.8 GMFB GMF ENSG00000197045 Glia maturation factor, beta 14 54474484-54489196 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002954 Approved Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:9.48e-5 (favourable), Liver cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 109.0 GMFG ENSG00000130755 Glia maturation factor, gamma 19 39328353-39342372 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002954 Uncertain Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:9.11e-6 (unfavourable), Cervical cancer:7.35e-4 (favourable) Expressed in all Expressed in all spleen: 313.5 GMNN Gem ENSG00000112312 Geminin, DNA replication inhibitor 6 24774931-24786099 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011458, CAB047327, CAB047328, HPA049977, HPA054597 Supported Validated Nucleoplasm Renal cancer:7.82e-5 (unfavourable), Ovarian cancer:4.13e-4 (favourable), Pancreatic cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all prostate: 70.5 GMPPA ENSG00000144591 GDP-mannose pyrophosphorylase A 2 219498867-219506989 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035512, HPA035513 Approved Approved Nucleoplasm Renal cancer:1.90e-10 (unfavourable), Liver cancer:1.62e-4 (unfavourable), Stomach cancer:5.24e-4 (favourable) Expressed in all Expressed in all epididymis: 82.6 GMPPB KIAA1851 ENSG00000173540 GDP-mannose pyrophosphorylase B 3 49716844-49723951 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA014657 Uncertain Supported Nucleus Endometrial cancer:6.19e-6 (favourable), Renal cancer:3.17e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.9 GMPR ENSG00000137198 Guanosine monophosphate reductase 6 16238580-16295549 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000904, HPA021476 Uncertain Renal cancer:2.94e-5 (favourable), Ovarian cancer:2.06e-4 (favourable), Lung cancer:8.07e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 105.8 GMPR2 ENSG00000100938 Guanosine monophosphate reductase 2 14 24232422-24239242 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000904, HPA067884, HPA068782 Uncertain Approved Nucleoplasm
Nucleoli Renal cancer:2.21e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 217.9 GMPS ENSG00000163655 Guanine monophosphate synthase 3 155870536-155944026 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046630 Approved Cytosol Liver cancer:8.73e-7 (unfavourable), Endometrial cancer:5.54e-5 (unfavourable), Pancreatic cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all testis: 180.7 GNA11 FBH, FBH2, FHH2, HHC2 ENSG00000088256 Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 19 3094410-3124004 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048886 Approved Renal cancer:1.48e-11 (favourable), Liver cancer:4.86e-4 (unfavourable) Expressed in all Expressed in all small intestine: 159.0 GNA12 gep ENSG00000146535 Guanine nucleotide binding protein (G protein) alpha 12 7 2728112-2844324 Predicted intracellular proteins Evidence at protein level CAB010046 Approved Approved Cytosol Liver cancer:1.20e-6 (unfavourable), Renal cancer:4.71e-5 (unfavourable), Urothelial cancer:2.27e-4 (unfavourable) Expressed in all Expressed in all placenta: 34.4 GNA13 G13, MGC46138 ENSG00000120063 Guanine nucleotide binding protein (G protein), alpha 13 17 65010715-65056839 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA010087 Approved Supported Cytosol Expressed in all Expressed in all bone marrow: 99.3 GNAI1 ENSG00000127955 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 7 80133955-80219402 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022449, HPA042141 Approved Supported Nucleus
Nucleoli
Centrosome Melanoma:5.09e-4 (unfavourable), Stomach cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 94.8 GNAI2 GIP, GNAI2B ENSG00000114353 Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3 50226292-50259355 Predicted intracellular proteins Evidence at protein level HPA007704 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Breast cancer:1.03e-4 (favourable) Expressed in all Expressed in all spleen: 329.9 GNAQ G-ALPHA-q, GAQ ENSG00000156052 Guanine nucleotide binding protein (G protein), q polypeptide 9 77716087-78031458 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB010036, HPA048886 Uncertain Approved Nuclear speckles
Plasma membrane
Cytosol Renal cancer:1.11e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 85.1 GNAS GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI ENSG00000087460 GNAS complex locus 20 58839718-58911192 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010337, HPA018122, HPA027478, HPA028386 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:3.49e-4 (unfavourable), Ovarian cancer:8.76e-4 (favourable) Expressed in all Expressed in all thyroid gland: 1471.9 GNB1 ENSG00000078369 Guanine nucleotide binding protein (G protein), beta polypeptide 1 1 1785285-1891117 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA040736 Supported Uncertain Golgi apparatus
Plasma membrane Liver cancer:3.61e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 448.5 GNB2 ENSG00000172354 Guanine nucleotide binding protein (G protein), beta polypeptide 2 7 100673531-100679174 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010032, HPA040736 Approved Approved Plasma membrane Expressed in all Expressed in all esophagus: 236.4 GNB2L1 Gnb2-rs1, H12.3, RACK1 ENSG00000204628 Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 5 181236909-181248096 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004288, HPA021676 Uncertain Validated Nucleoplasm
Cytosol Liver cancer:2.98e-6 (unfavourable) Expressed in all Expressed in all ovary: 2104.6 GNE IBM2, Uae1 ENSG00000159921 Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 9 36214441-36277056 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007045, HPA027258 Approved Supported Cytosol Renal cancer:9.28e-11 (favourable) Expressed in all Expressed in all rectum: 54.2 GNG10 ENSG00000242616 Guanine nucleotide binding protein (G protein), gamma 10 9 111661335-111670246 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Head and neck cancer:3.21e-5 (unfavourable) Expressed in all Expressed in all appendix: 92.5 GNG11 GNGT11 ENSG00000127920 Guanine nucleotide binding protein (G protein), gamma 11 7 93921699-93928610 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA045255 Uncertain Expressed in all Expressed in all placenta: 122.3 GNG2 ENSG00000186469 Guanine nucleotide binding protein (G protein), gamma 2 14 51826195-51979342 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003534, CAB018380 Uncertain Supported Approved Golgi apparatus
Vesicles Renal cancer:3.90e-6 (unfavourable), Pancreatic cancer:1.64e-4 (favourable) Expressed in all Expressed in all testis: 184.7 GNG5 ENSG00000174021 Guanine nucleotide binding protein (G protein), gamma 5 1 84498325-84506565 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB032623, HPA043651 Approved Liver cancer:3.23e-5 (unfavourable) Expressed in all Expressed in all lung: 133.8 GNG7 FLJ00058 ENSG00000176533 Guanine nucleotide binding protein (G protein), gamma 7 19 2511219-2702709 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA057790 Approved Renal cancer:0.00e+0 (favourable), Lung cancer:1.35e-5 (favourable), Liver cancer:3.05e-4 (favourable), Pancreatic cancer:3.71e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 49.9 GNL2 HUMAUANTIG, Ngp-1, Nog2, Nug2 ENSG00000134697 Guanine nucleotide binding protein-like 2 (nucleolar) 1 37566816-37595935 Predicted intracellular proteins Evidence at protein level HPA027163, HPA060026 Approved Validated Nucleoli Renal cancer:2.90e-11 (unfavourable), Liver cancer:5.86e-9 (unfavourable), Ovarian cancer:7.89e-4 (favourable) Expressed in all Expressed in all testis: 55.3 GNL3 C77032, E2IG3, MGC800, NS ENSG00000163938 Guanine nucleotide binding protein-like 3 (nucleolar) 3 52681156-52694492 Predicted intracellular proteins Evidence at protein level CAB020770, HPA036742, HPA036743 Supported Validated Nucleoli
Nuclear bodies Renal cancer:5.69e-5 (unfavourable), Liver cancer:2.93e-4 (unfavourable), Prostate cancer:6.11e-4 (unfavourable) Expressed in all Expressed in all breast: 78.2 GNL3L FLJ10613 ENSG00000130119 Guanine nucleotide binding protein-like 3 (nucleolar)-like X 54530211-54561071 Predicted intracellular proteins Evidence at protein level HPA036314, HPA036315 Supported Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all thyroid gland: 16.4 GNPAT DAP-AT, DAPAT, DHAPAT ENSG00000116906 Glyceronephosphate O-acyltransferase 1 231241207-231277973 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:8.29e-6 (unfavourable) Expressed in all Expressed in all testis: 59.5 GNPDA1 GNPDA, GNPI, GPI, HLN, KIAA0060 ENSG00000113552 Glucosamine-6-phosphate deaminase 1 5 141991749-142013041 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000499, HPA046891 Uncertain Approved Golgi apparatus
Vesicles Liver cancer:2.60e-6 (unfavourable) Expressed in all Expressed in all kidney: 77.1 GNPDA2 SB52 ENSG00000163281 Glucosamine-6-phosphate deaminase 2 4 44682200-44726595 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000499, HPA046891 Uncertain Approved Golgi apparatus
Vesicles Expressed in all Expressed in all thyroid gland: 32.5 GNPNAT1 FLJ10607, Gpnat1 ENSG00000100522 Glucosamine-phosphate N-acetyltransferase 1 14 52775194-52791668 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044647 Approved Pancreatic cancer:8.52e-5 (unfavourable) Expressed in all Expressed in all liver: 39.5 GNPTAB GNPTA, KIAA1208, MGC4170 ENSG00000111670 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 12 101745497-101830938 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017754, HPA042343 Approved Approved Vesicles Endometrial cancer:8.48e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 64.0 GNPTG C16orf27, c316G12.3, CAB56184, GNPTAG ENSG00000090581 N-acetylglucosamine-1-phosphate transferase, gamma subunit 16 1351923-1364113 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA004055 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all adrenal gland: 66.6 GNS ENSG00000135677 Glucosamine (N-acetyl)-6-sulfatase 12 64713445-64759447 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013695, CAB026011, HPA048508 Supported Liver cancer:1.94e-5 (unfavourable), Glioma:4.17e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 173.8 GOLGA1 golgin-97, MGC33154 ENSG00000136935 Golgin A1 9 124878357-124948492 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013065, HPA044329, HPA050555 Supported Validated Golgi apparatus Endometrial cancer:2.21e-4 (favourable) Expressed in all Expressed in all testis: 28.7 GOLGA2 GM130, golgin-95 ENSG00000167110 Golgin A2 9 128255829-128275995 Predicted intracellular proteins Evidence at protein level CAB015421, HPA021178, HPA021230, HPA021799 Supported Validated Golgi apparatus Renal cancer:9.77e-5 (favourable), Colorectal cancer:1.64e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 158.4 GOLGA3 GCP170, golgin-160, MEA-2 ENSG00000090615 Golgin A3 12 132768909-132828858 Predicted intracellular proteins Evidence at protein level HPA039809, HPA040044 Supported Supported Nucleus
Golgi apparatus Renal cancer:6.47e-5 (unfavourable), Liver cancer:2.73e-4 (unfavourable), Pancreatic cancer:3.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 18.5 GOLGA4 GCP2, GOLG, golgin-240, p230 ENSG00000144674 Golgin A4 3 37243177-37366751 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035102 Supported Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:3.62e-6 (favourable) Expressed in all Expressed in all testis: 80.6 GOLGA5 golgin-84, GOLIM5, ret-II, rfg5 ENSG00000066455 Golgin A5 14 92794231-92839963 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000992, HPA063876 Supported Supported Supported Golgi apparatus Expressed in all Expressed in all epididymis: 64.2 GOLGA7 GCP16, GOLGA3AP1, GOLGA7A, HSPC041 ENSG00000147533 Golgin A7 8 41490396-41510980 Predicted intracellular proteins Evidence at protein level HPA046878 Uncertain Endometrial cancer:1.36e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 96.7 GOLGA8N ENSG00000232653 Golgin A8 family, member N 15 32593456-32607310 Predicted intracellular proteins Evidence at transcript level Mixed Expressed in all thyroid gland: 46.4 GOLGB1 GCP, GCP372, giantin, GOLIM1 ENSG00000173230 Golgin B1 3 121663199-121749767 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011008, HPA011555 Supported Validated Golgi apparatus Expressed in all Expressed in all prostate: 42.4 GOLIM4 GIMPC, GOLPH4, GPP130, P138 ENSG00000173905 Golgi integral membrane protein 4 3 168008677-168095975 Predicted membrane proteins Evidence at protein level HPA001677, HPA002315 Supported Validated Golgi apparatus Expressed in all Expressed in all small intestine: 95.7 GOLM1 bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73 ENSG00000135052 Golgi membrane protein 1 9 86026146-86100173 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA010638, HPA011929, CAB015341 Supported Validated Golgi apparatus Endometrial cancer:8.14e-5 (favourable), Liver cancer:1.30e-4 (unfavourable) Expressed in all Expressed in all stomach: 406.6 GOLPH3 GOPP1, GPP34, MIDAS, Vps74 ENSG00000113384 Golgi phosphoprotein 3 (coat-protein) 5 32124704-32174350 Predicted intracellular proteins Evidence at protein level HPA044564, HPA055841 Approved Supported Golgi apparatus
Vesicles Expressed in all Expressed in all gallbladder: 120.9 GOLPH3L GPP34R ENSG00000143457 Golgi phosphoprotein 3-like 1 150646225-150697144 Predicted intracellular proteins Evidence at protein level HPA028558 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 51.2 GOLT1B CGI-141, GOT1, YMR292W ENSG00000111711 Golgi transport 1B 12 21501781-21518408 Predicted membrane proteins Evidence at protein level HPA055909, HPA066383 Approved Approved Vesicles Renal cancer:4.83e-10 (unfavourable), Liver cancer:1.99e-8 (unfavourable), Pancreatic cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all placenta: 42.1 GON4L FLJ20203, GON-4, GON4 ENSG00000116580 Gon-4-like (C. elegans) 1 155749662-155859400 Predicted intracellular proteins Evidence at protein level HPA006986, HPA057305, HPA074504 Uncertain Validated Nucleoplasm
Nuclear bodies Endometrial cancer:4.19e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.6 GOPC CAL, dJ94G16.2, FIG, GOPC1, PIST ENSG00000047932 Golgi-associated PDZ and coiled-coil motif containing 6 117560269-117602542 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019477, HPA024018 Approved Validated Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 47.0 GORASP1 FLJ23443, GOLPH5, GRASP65, P65 ENSG00000114745 Golgi reassembly stacking protein 1, 65kDa 3 39096659-39108363 Predicted intracellular proteins Evidence at protein level HPA056283 Supported Supported Golgi apparatus Renal cancer:1.91e-6 (favourable), Endometrial cancer:6.92e-6 (favourable), Liver cancer:5.13e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 36.7 GORASP2 GOLPH6, GRASP55, GRS2 ENSG00000115806 Golgi reassembly stacking protein 2, 55kDa 2 170928464-170967129 Predicted intracellular proteins Evidence at protein level HPA035274, HPA035275 Supported Validated Golgi apparatus Renal cancer:1.38e-8 (unfavourable), Head and neck cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all epididymis: 41.5 GOSR1 GOLIM2, GOS-28, GOS28, GS28, P28 ENSG00000108587 Golgi SNAP receptor complex member 1 17 30477362-30527592 Predicted membrane proteins Evidence at protein level HPA020590 Uncertain Renal cancer:2.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 54.8 GOSR2 Bos1, GS27 ENSG00000108433 Golgi SNAP receptor complex member 2 17 46923117-46967019 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB017456, HPA048956, HPA054472 Uncertain Supported Nucleoplasm
Golgi apparatus Liver cancer:3.80e-4 (unfavourable) Expressed in all Expressed in all testis: 132.2 GOT1 AST1 ENSG00000120053 Glutamic-oxaloacetic transaminase 1, soluble 10 99396870-99430624 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064532, HPA072629 Supported Supported Nucleoplasm
Cytosol Renal cancer:3.72e-13 (favourable), Cervical cancer:6.23e-4 (favourable) Expressed in all Expressed in all heart muscle: 340.8 GOT2 KAT4, KATIV, mitAAT ENSG00000125166 Glutamic-oxaloacetic transaminase 2, mitochondrial 16 58707131-58734357 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA018139 Supported Renal cancer:2.90e-9 (favourable), Liver cancer:5.75e-5 (favourable), Head and neck cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 240.3 GPAA1 GAA1, hGAA1 ENSG00000197858 Glycosylphosphatidylinositol anchor attachment 1 8 144082590-144086216 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 68.8 GPALPP1 AD029, bA245H20.2, KIAA1704, LSR7 ENSG00000133114 GPALPP motifs containing 1 13 44989529-45037669 Predicted intracellular proteins Evidence at protein level HPA038966, HPA058739 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 15.4 GPAM GPAT1, KIAA1560, MGC26846 ENSG00000119927 Glycerol-3-phosphate acyltransferase, mitochondrial 10 112149864-112215377 Enzymes, Predicted membrane proteins Evidence at protein level HPA046339, HPA060090 Approved Approved Mitochondria Renal cancer:4.54e-6 (favourable) Tissue enriched Expressed in all adipose tissue: 315.5 GPAT4 AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7 ENSG00000158669 Glycerol-3-phosphate acyltransferase 4 8 41577187-41625001 Enzymes, Predicted membrane proteins Evidence at protein level HPA016471 Approved Ovarian cancer:2.20e-4 (unfavourable), Prostate cancer:4.15e-4 (favourable), Urothelial cancer:5.65e-4 (favourable), Endometrial cancer:9.37e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 78.7 GPATCH2L C14orf118, FLJ10033, FLJ20689 ENSG00000089916 G patch domain containing 2-like 14 76151916-76254342 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018856 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all bone marrow: 39.9 GPATCH3 FLJ12455, GPATC3 ENSG00000198746 G patch domain containing 3 1 26890488-26900466 Predicted intracellular proteins Evidence at protein level HPA032078, HPA054973 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.23e-7 (unfavourable), Pancreatic cancer:6.42e-4 (favourable) Expressed in all Expressed in all bone marrow: 15.3 GPATCH4 DKFZP434F1735, FLJ20249, GPATC4 ENSG00000160818 G patch domain containing 4 1 156594487-156601496 Predicted intracellular proteins Evidence at protein level HPA028323, HPA054319 Approved Supported Nucleus
Nucleoli Liver cancer:3.17e-5 (unfavourable), Renal cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.2 GPBP1 DKFZp761C169, vasculin ENSG00000062194 GC-rich promoter binding protein 1 5 57173948-57264679 Predicted intracellular proteins Evidence at protein level HPA037773 Approved Approved Vesicles
Plasma membrane
Cytosol Urothelial cancer:4.15e-5 (favourable) Expressed in all Expressed in all testis: 138.1 GPBP1L1 SP192 ENSG00000159592 GC-rich promoter binding protein 1-like 1 1 45627304-45688113 Predicted intracellular proteins Evidence at protein level HPA028593 Approved Approved Nucleoplasm
Plasma membrane
Focal adhesion sites Expressed in all Expressed in all testis: 106.6 GPCPD1 GDE5, GDPD6, KIAA1434 ENSG00000125772 Glycerophosphocholine phosphodiesterase 1 20 5544404-5611026 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039556, HPA042987 Uncertain Approved Nucleoplasm Endometrial cancer:1.30e-4 (favourable), Renal cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 46.6 GPD1L KIAA0089 ENSG00000152642 Glycerol-3-phosphate dehydrogenase 1-like 3 32105689-32168713 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:3.33e-15 (favourable), Liver cancer:1.35e-5 (unfavourable), Lung cancer:5.71e-5 (favourable), Colorectal cancer:7.05e-4 (favourable) Expressed in all Expressed in all prostate: 97.8 GPD2 ENSG00000115159 Glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2 156435290-156613735 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008012, HPA045506 Supported Liver cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.9 GPHN KIAA1385 ENSG00000171723 Gephyrin 14 66507407-67181803 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003116, CAB004419, HPA024694 Supported Uncertain Cytoplasmic bodies Renal cancer:5.25e-12 (favourable), Urothelial cancer:4.61e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.5 GPI AMF, NLK ENSG00000105220 Glucose-6-phosphate isomerase 19 34359480-34402156 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB018655, HPA024305, CAB040563, HPA052171 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 308.2 GPKOW GPATC5, GPATCH5, Spp2, T54 ENSG00000068394 G patch domain and KOW motifs X 49113389-49123801 Predicted intracellular proteins Evidence at protein level HPA000287, HPA001894 Supported Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 30.9 GPN1 ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1 ENSG00000198522 GPN-loop GTPase 1 2 27628247-27651508 Predicted intracellular proteins Evidence at protein level HPA036793, HPA036794, CAB037303 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Liver cancer:1.71e-5 (unfavourable), Endometrial cancer:2.88e-5 (unfavourable) Expressed in all Expressed in all testis: 47.2 GPN2 ATPBD1B, FLJ10349 ENSG00000142751 GPN-loop GTPase 2 1 26876133-26890297 Predicted intracellular proteins Evidence at protein level HPA028059 Uncertain Liver cancer:3.56e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.1 GPN3 ATPBD1C, MGC14560 ENSG00000111231 GPN-loop GTPase 3 12 110452484-110469268 Predicted intracellular proteins Evidence at protein level HPA039764, HPA047793 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:2.65e-6 (favourable), Liver cancer:3.98e-5 (unfavourable) Expressed in all Expressed in all testis: 73.9 GPNMB HGFIN, NMB ENSG00000136235 Glycoprotein (transmembrane) nmb 7 23235967-23275108 Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all skin: 656.2 GPR107 FLJ20998, KIAA1624, LUSTR1, RP11-88G17 ENSG00000148358 G protein-coupled receptor 107 9 130053426-130140169 Predicted membrane proteins Evidence at protein level HPA031704 Supported Approved Nucleoplasm
Golgi apparatus Renal cancer:1.87e-5 (favourable), Breast cancer:3.56e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 55.1 GPR108 LUSTR2 ENSG00000125734 G protein-coupled receptor 108 19 6729914-6737603 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041924, HPA041951, HPA063863 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:1.29e-9 (favourable), Endometrial cancer:1.04e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 73.7 GPR137 C11orf4, GPR137A, TM7SF1L1 ENSG00000173264 G protein-coupled receptor 137 11 64270062-64289500 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA062871 Uncertain Approved Nucleus
Nucleoli
Actin filaments Liver cancer:5.34e-4 (unfavourable), Pancreatic cancer:6.18e-4 (favourable) Expressed in all Expressed in all testis: 147.8 GPR146 PGR8 ENSG00000164849 G protein-coupled receptor 146 7 1044576-1059261 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Mixed Expressed in all adipose tissue: 35.4 GPR155 DEP.7, DEPDC3, FLJ31819, PGR22 ENSG00000163328 G protein-coupled receptor 155 2 174431571-174487094 Predicted membrane proteins Evidence at protein level HPA036159, HPA057384 Approved Approved Nuclear bodies
Cytosol Expressed in all Expressed in all stomach: 44.0 GPR89B GPR89, GPR89C, SH120 ENSG00000188092 G protein-coupled receptor 89B 1 147928393-147993521 Predicted membrane proteins Evidence at protein level HPA076096 Approved Endoplasmic reticulum Mixed Expressed in all kidney: 30.9 GPS1 COPS1, CSN1 ENSG00000169727 G protein pathway suppressor 1 17 82050691-82057470 Plasma proteins, Predicted intracellular proteins Evidence at protein level Ovarian cancer:3.06e-4 (favourable) Expressed in all Expressed in all testis: 77.1 GPS2 ENSG00000132522 G protein pathway suppressor 2 17 7311324-7315564 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA067540 Supported Nucleoplasm Renal cancer:3.42e-5 (unfavourable), Pancreatic cancer:7.50e-5 (favourable) Expressed in all Expressed in all testis: 97.2 GPT2 ALT2 ENSG00000166123 Glutamic pyruvate transaminase (alanine aminotransferase) 2 16 46884378-46931297 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051514 Approved Approved Mitochondria Ovarian cancer:3.17e-4 (favourable) Expressed in all Expressed in all esophagus: 85.4 GPX1 ENSG00000233276 Glutathione peroxidase 1 3 49357176-49358600 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011582, HPA044758 Approved Supported Cytosol Endometrial cancer:7.78e-4 (favourable) Expressed in all Expressed in all adipose tissue: 275.5 GPX3 ENSG00000211445 Glutathione peroxidase 3 5 151020438-151028993 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB069456 Uncertain Stomach cancer:1.65e-4 (unfavourable) Expressed in all Expressed in all kidney: 11584.2 GPX4 MCSP, PHGPx ENSG00000167468 Glutathione peroxidase 4 19 1103926-1106791 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008630, HPA047224, HPA058546 Supported Supported Nucleoplasm
Mitochondria Endometrial cancer:1.84e-5 (favourable), Cervical cancer:7.18e-4 (favourable), Pancreatic cancer:7.72e-4 (favourable), Renal cancer:8.61e-4 (favourable) Expressed in all Expressed in all testis: 1137.7 GPX7 FLJ14777, GPX6, NPGPx ENSG00000116157 Glutathione peroxidase 7 1 52602372-52609051 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA025829 Approved Nucleoli Renal cancer:2.26e-5 (unfavourable) Expressed in all Expressed in all placenta: 41.7 GRAMD1A FLJ90346, KIAA1533 ENSG00000089351 GRAM domain containing 1A 19 34994784-35026471 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008852, HPA012570 Approved Approved Plasma membrane
Cytosol Renal cancer:7.95e-12 (unfavourable) Expressed in all Expressed in all appendix: 36.8 GRAMD4 DIP, KIAA0767 ENSG00000075240 GRAM domain containing 4 22 46576012-46679790 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Head and neck cancer:3.04e-4 (favourable) Expressed in all Expressed in all skin: 53.3 GRB10 ENSG00000106070 Growth factor receptor-bound protein 10 7 50590063-50793462 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB019423, HPA027502, HPA031818 Approved Approved Nuclear membrane
Vesicles Expressed in all Expressed in all thyroid gland: 44.8 GRB2 NCKAP2 ENSG00000177885 Growth factor receptor-bound protein 2 17 75318076-75405709 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002589, HPA030749, HPA030750 Approved Supported Nucleus Liver cancer:6.04e-7 (unfavourable) Expressed in all Expressed in all appendix: 138.6 GRHPR GLXR, PH2 ENSG00000137106 Glyoxylate reductase/hydroxypyruvate reductase 9 37422666-37436990 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022971 Approved Approved Nucleoplasm
Cytosol Renal cancer:5.39e-9 (favourable), Breast cancer:7.00e-5 (favourable) Expressed in all Expressed in all liver: 322.8 GRINA HNRGW, LFG1, NMDARA1, TMBIM3 ENSG00000178719 Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 8 143990058-143993415 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA036980, HPA036981 Approved Approved Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all seminal vesicle: 261.5 GRIPAP1 DKFZp434P0630, GRASP-1, GRASP1, KIAA1167, MPMGp800B12492Q3 ENSG00000068400 GRIP1 associated protein 1 X 48973720-49002264 Predicted intracellular proteins Evidence at protein level HPA000282, HPA000615 Approved Approved Vesicles
Cytosol Renal cancer:3.92e-7 (unfavourable), Urothelial cancer:4.63e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 68.7 GRK5 GPRK5 ENSG00000198873 G protein-coupled receptor kinase 5 10 119207589-119459742 Enzymes, Predicted intracellular proteins Evidence at protein level CAB025579, HPA046838 Approved Approved Nuclear membrane
Nuclear speckles
Plasma membrane Renal cancer:2.38e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 77.1 GRK6 GPRK6 ENSG00000198055 G protein-coupled receptor kinase 6 5 177403204-177442901 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015327, HPA018903 Approved Approved Mitochondria Liver cancer:5.66e-6 (unfavourable), Pancreatic cancer:1.22e-4 (favourable) Expressed in all Expressed in all bone marrow: 87.7 GRN CLN11, PCDGF, PGRN ENSG00000030582 Granulin 17 44345086-44353102 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008763, CAB019394, HPA028747 Approved Validated Endoplasmic reticulum
Endosomes
Lysosomes Glioma:6.36e-4 (unfavourable) Expressed in all Expressed in all lung: 425.0 GRPEL1 FLJ25609, GrpE, hMGE ENSG00000109519 GrpE-like 1, mitochondrial (E. coli) 4 7058906-7068197 Predicted intracellular proteins Evidence at protein level HPA036647 Supported Supported Mitochondria Renal cancer:2.00e-6 (favourable) Expressed in all Expressed in all adrenal gland: 44.1 GRSF1 ENSG00000132463 G-rich RNA sequence binding factor 1 4 70815782-70839945 Predicted intracellular proteins Evidence at protein level HPA036984, HPA036985 Supported Validated Mitochondria Renal cancer:2.72e-9 (favourable), Colorectal cancer:1.47e-5 (favourable), Liver cancer:8.29e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 95.8 GRWD1 GRWD, RRB1, WDR28 ENSG00000105447 Glutamate-rich WD repeat containing 1 19 48445773-48457022 Predicted intracellular proteins Evidence at protein level HPA042643, HPA055680 Approved Supported Nucleus
Nucleoli Liver cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.8 GSDMD DF5L, FLJ12150, GSDMDC1 ENSG00000104518 Gasdermin D 8 143553207-143563062 Predicted intracellular proteins Evidence at protein level CAB004656, HPA044487 Uncertain Supported Nucleoplasm Renal cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all spleen: 47.4 GSE1 KIAA0182 ENSG00000131149 Gse1 coiled-coil protein 16 85611409-85676204 Predicted intracellular proteins Evidence at protein level HPA036365 Uncertain Approved Nucleoplasm
Mitochondria Pancreatic cancer:5.20e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 55.8 GSK3A ENSG00000105723 Glycogen synthase kinase 3 alpha 19 42230186-42242625 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB004422, HPA028423 Approved Approved Cytosol Liver cancer:1.13e-4 (unfavourable), Endometrial cancer:4.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 74.7 GSK3B ENSG00000082701 Glycogen synthase kinase 3 beta 3 119821323-120094417 Enzymes, Predicted intracellular proteins Evidence at protein level CAB016263, HPA028017 Approved Validated Nucleus Liver cancer:8.20e-5 (unfavourable), Renal cancer:1.52e-4 (favourable) Expressed in all Expressed in all testis: 47.2 GSKIP C14orf129 ENSG00000100744 GSK3B interacting protein 14 96363452-96387288 Predicted intracellular proteins Evidence at protein level HPA043054, HPA046782 Approved Approved Nucleoli
Golgi apparatus
Vesicles Expressed in all Expressed in all small intestine: 63.2 GSN DKFZp313L0718 ENSG00000148180 Gelsolin 9 121207794-121332843 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010823, CAB016728, CAB036009, HPA054026 Supported Supported Actin filaments Urothelial cancer:1.79e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 1336.6 GSPT1 eRF3a, ETF3A, GST1 ENSG00000103342 G1 to S phase transition 1 16 11868128-11916082 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052488 Approved Approved Vesicles
Cytosol Colorectal cancer:2.10e-5 (favourable), Renal cancer:3.06e-5 (favourable), Liver cancer:7.94e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 130.4 GSPT2 eRF3b, FLJ10441 ENSG00000189369 G1 to S phase transition 2 X 51743431-51746232 Predicted intracellular proteins Evidence at protein level HPA044769 Approved Supported Cytosol Expressed in all Expressed in all testis: 24.4 GSR ENSG00000104687 Glutathione reductase 8 30678061-30727926 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001538, CAB008632 Approved Supported Plasma membrane
Cytosol Liver cancer:3.26e-5 (unfavourable), Colorectal cancer:4.08e-5 (favourable), Renal cancer:1.80e-4 (favourable), Cervical cancer:3.37e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 77.8 GSS ENSG00000100983 Glutathione synthetase 20 34928430-34955817 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054508, HPA059315 Supported Supported Nucleus Renal cancer:7.31e-6 (favourable), Liver cancer:7.21e-5 (unfavourable) Expressed in all Expressed in all epididymis: 104.1 GSTA4 ENSG00000170899 Glutathione S-transferase alpha 4 6 52977948-52995378 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048934 Approved Expressed in all Expressed in all adrenal gland: 391.8 GSTK1 GST13 ENSG00000197448 Glutathione S-transferase kappa 1 7 143244093-143270854 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006311, HPA022904 Supported Supported Peroxisomes Renal cancer:2.10e-6 (favourable), Breast cancer:4.41e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 369.9 GSTM2 GST4 ENSG00000213366 Glutathione S-transferase mu 2 (muscle) 1 109668022-109709551 Enzymes, Predicted intracellular proteins Evidence at protein level CAB040547, HPA055972, HPA055973 Approved Supported Nucleoplasm
Vesicles
Cytosol Lung cancer:9.70e-5 (favourable) Mixed Expressed in all ovary: 200.5 GSTM3 GST5 ENSG00000134202 Glutathione S-transferase mu 3 (brain) 1 109733932-109741038 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB017130, HPA035190, CAB040583, HPA055972 Supported Supported Nucleoli
Cytosol Melanoma:1.89e-4 (unfavourable) Expressed in all Expressed in all testis: 718.1 GSTM4 ENSG00000168765 Glutathione S-transferase mu 4 1 109656081-109674836 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048652, HPA055972, HPA055973 Approved Approved Mitochondria Breast cancer:9.96e-5 (favourable) Expressed in all Expressed in all duodenum: 153.8 GSTO1 GSTTLp28, P28 ENSG00000148834 Glutathione S-transferase omega 1 10 104235356-104267459 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037603, HPA037604 Supported Renal cancer:2.11e-4 (unfavourable), Breast cancer:6.95e-4 (favourable), Head and neck cancer:8.83e-4 (unfavourable) Expressed in all Expressed in all liver: 265.4 GSTP1 FAEES3, GST3, GSTP ENSG00000084207 Glutathione S-transferase pi 1 11 67583595-67586660 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019779, HPA019869 Approved Supported Mitochondria
Cytosol Expressed in all Expressed in all esophagus: 1064.0 GSTZ1 GSTZ1-1, MAAI, MAI ENSG00000100577 Glutathione S-transferase zeta 1 14 77320884-77331597 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004701 Approved Approved Nucleus
Cytosol Renal cancer:1.12e-7 (favourable), Ovarian cancer:3.73e-4 (favourable), Breast cancer:4.93e-4 (favourable) Expressed in all Expressed in all liver: 133.9 GTDC1 FLJ11753, Hmat-Xa ENSG00000121964 Glycosyltransferase-like domain containing 1 2 143938068-144332568 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036694 Uncertain Approved Cytosol Renal cancer:6.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 29.5 GTF2A1 TFIIA ENSG00000165417 General transcription factor IIA, 1, 19/37kDa 14 81175452-81221377 Predicted intracellular proteins Evidence at protein level HPA000869 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 38.8 GTF2A2 HsT18745, TFIIA ENSG00000140307 General transcription factor IIA, 2, 12kDa 15 59638062-59657541 Predicted intracellular proteins Evidence at protein level HPA056239 Supported Nucleoplasm Expressed in all Expressed in all testis: 367.4 GTF2B TFIIB ENSG00000137947 General transcription factor IIB 1 88852932-88891944 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA061626 Supported Supported Nucleus
Nuclear bodies Breast cancer:4.81e-4 (favourable) Expressed in all Expressed in all bone marrow: 47.7 GTF2E2 FE, TF2E2, TFIIE-B ENSG00000197265 General transcription factor IIE, polypeptide 2, beta 34kDa 8 30578318-30658251 Predicted intracellular proteins Evidence at protein level HPA004816, CAB009603, HPA025065 Approved Validated Nucleoplasm
Cytosol Renal cancer:5.82e-7 (unfavourable) Expressed in all Expressed in all testis: 52.5 GTF2F1 BTF4, RAP74, TF2F1, TFIIF ENSG00000125651 General transcription factor IIF, polypeptide 1, 74kDa 19 6379569-6393981 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022793, HPA028707 Approved Validated Nucleus
Cell Junctions Endometrial cancer:8.39e-4 (favourable), Renal cancer:9.80e-4 (favourable) Expressed in all Expressed in all ovary: 93.6 GTF2F2 BTF4, RAP30, TFIIF ENSG00000188342 General transcription factor IIF, polypeptide 2, 30kDa 13 45120515-45284909 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006912 Supported Supported Nucleus
Microtubules Head and neck cancer:1.65e-5 (unfavourable) Expressed in all Expressed in all skin: 26.4 GTF2H1 BTF2, P62, TFIIH ENSG00000110768 General transcription factor IIH, polypeptide 1, 62kDa 11 18322295-18367044 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004637, HPA046660 Supported Validated Nucleoplasm Liver cancer:5.98e-9 (unfavourable) Expressed in all Expressed in all testis: 60.0 GTF2H3 BTF2, P34, TFIIH ENSG00000111358 General transcription factor IIH, polypeptide 3, 34kDa 12 123633739-123662606 Predicted intracellular proteins Evidence at protein level HPA004844, HPA053562 Uncertain Supported Nucleoplasm Liver cancer:6.72e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 26.7 GTF2I BAP-135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBSCR6 ENSG00000263001 General transcription factor IIi 7 74657667-74760692 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004595, HPA026638 Supported Validated Nucleoplasm Renal cancer:6.35e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 227.9 GTF2IRD2 FLJ37938, GTF2IRD2A ENSG00000196275 GTF2I repeat domain containing 2 7 74796144-74851551 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056679, HPA056680 Approved Nucleoplasm Mixed Expressed in all ovary: 16.2 GTF2IRD2B ENSG00000174428 GTF2I repeat domain containing 2B 7 75092573-75149817 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056679, HPA056680 Approved Nucleoplasm Breast cancer:3.27e-4 (favourable) Mixed Expressed in all ovary: 40.4 GTF3A AP2, TFIIIA ENSG00000122034 General transcription factor IIIA 13 27424544-27435823 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007990 Supported Supported Nucleus Renal cancer:3.43e-6 (unfavourable) Expressed in all Expressed in all lymph node: 99.6 GTF3C1 TFIIIC220 ENSG00000077235 General transcription factor IIIC, polypeptide 1, alpha 220kDa 16 27459555-27549913 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051617 Approved Supported Nucleus
Nucleoli Renal cancer:1.25e-4 (favourable), Liver cancer:8.73e-4 (unfavourable), Pancreatic cancer:9.56e-4 (favourable) Expressed in all Expressed in all thyroid gland: 49.6 GTF3C2 KIAA0011, TFIIIC110 ENSG00000115207 General transcription factor IIIC, polypeptide 2, beta 110kDa 2 27325849-27357034 Predicted intracellular proteins Evidence at protein level HPA035836 Uncertain Liver cancer:1.21e-8 (unfavourable), Endometrial cancer:8.25e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 55.0 GTF3C3 TFIIIC102, TFiiiC2-102 ENSG00000119041 General transcription factor IIIC, polypeptide 3, 102kDa 2 196763032-196799725 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA069179 Supported Nucleus
Nuclear membrane Liver cancer:1.26e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.1 GTF3C4 KAT12, TFIIIC90 ENSG00000125484 General transcription factor IIIC, polypeptide 4, 90kDa 9 132670035-132694955 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069369 Supported Nucleus Renal cancer:2.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 16.7 GTF3C5 TFiiiC2-63, TFIIIC63, TFIIICepsilon ENSG00000148308 General transcription factor IIIC, polypeptide 5, 63kDa 9 133030675-133058503 Predicted intracellular proteins Evidence at protein level HPA067063, HPA069805 Supported Validated Nucleoplasm Expressed in all Expressed in all ovary: 48.1 GTF3C6 bA397G5.3, C6orf51, TFIIIC35 ENSG00000155115 General transcription factor IIIC, polypeptide 6, alpha 35kDa 6 110958560-110967890 Predicted intracellular proteins Evidence at protein level HPA056179, HPA061345 Approved Supported Nucleoplasm
Nuclear bodies Liver cancer:7.27e-6 (unfavourable) Expressed in all Expressed in all prostate: 99.9 GTPBP1 GP-1, HSPC018 ENSG00000100226 GTP binding protein 1 22 38705723-38738299 Predicted intracellular proteins Evidence at protein level HPA003166, HPA064702 Uncertain Approved Nuclear bodies
Golgi apparatus
Cytosol Liver cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 65.1 GTPBP10 DKFZP686A10121, FLJ38242 ENSG00000105793 GTP-binding protein 10 (putative) 7 90335223-90391455 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021076 Approved Renal cancer:6.76e-5 (favourable) Expressed in all Expressed in all testis: 20.4 GTPBP2 ENSG00000172432 GTP binding protein 2 6 43605316-43629162 Predicted intracellular proteins Evidence at protein level HPA031418, HPA031419 Approved Validated Vesicles Renal cancer:1.44e-15 (unfavourable), Liver cancer:1.08e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 46.5 GTPBP3 FLJ14700, GTPBG3, MSS1, MTGP1, THDF1 ENSG00000130299 GTP binding protein 3 (mitochondrial) 19 17334920-17342735 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042158 Approved Supported Mitochondria Renal cancer:1.64e-4 (unfavourable), Liver cancer:1.86e-4 (unfavourable), Prostate cancer:2.81e-4 (unfavourable) Expressed in all Expressed in all skin: 12.4 GTPBP4 CRFG, FLJ10686, FLJ10690, NGB, NOG1 ENSG00000107937 GTP binding protein 4 10 988019-1019936 Predicted intracellular proteins Evidence at protein level HPA039618, HPA056468 Uncertain Validated Nuclear membrane
Nucleoli Liver cancer:8.85e-12 (unfavourable), Renal cancer:2.38e-5 (unfavourable), Endometrial cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all testis: 37.2 GTPBP6 FLJ20977, PGPL ENSG00000178605 GTP binding protein 6 (putative) X 304529-318819 Predicted intracellular proteins Evidence at protein level CAB034924, HPA035467, HPA055418 Approved Uncertain Mitochondria Pancreatic cancer:1.71e-4 (favourable), Liver cancer:8.87e-4 (unfavourable) Expressed in all Expressed in all spleen: 26.7 GTPBP8 HSPC135 ENSG00000163607 GTP-binding protein 8 (putative) 3 112990918-113015060 Predicted intracellular proteins Evidence at protein level HPA034831, HPA058631 Approved Validated Mitochondria Renal cancer:3.07e-5 (favourable) Expressed in all Expressed in all testis: 32.8 GUCD1 C22orf13, LLN4, MGC1842 ENSG00000138867 Guanylyl cyclase domain containing 1 22 24540423-24555935 Predicted intracellular proteins Evidence at protein level HPA022786 Approved Nucleoplasm Cervical cancer:6.84e-4 (favourable), Ovarian cancer:7.26e-4 (favourable) Expressed in all Expressed in all duodenum: 64.7 GUCY1B3 GC-S-beta-1, GC-SB3, GUC1B3 ENSG00000061918 Guanylate cyclase 1, soluble, beta 3 4 155758992-155807591 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010890, HPA020870 Approved Approved Cytosol Renal cancer:2.42e-4 (unfavourable), Testis cancer:3.23e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 174.2 GUK1 ENSG00000143774 Guanylate kinase 1 1 228139962-228148984 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028118, HPA048587 Approved Uncertain Nucleoplasm
Cytosol Renal cancer:8.85e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 265.5 GUSB ENSG00000169919 Glucuronidase, beta 7 65960684-65982314 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA036322, HPA036323 Approved Supported Vesicles Expressed in all Expressed in all breast: 94.1 GYG1 GYG ENSG00000163754 Glycogenin 1 3 148991341-149027668 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030497 Approved Supported Vesicles Liver cancer:6.15e-5 (unfavourable) Expressed in all Expressed in all testis: 209.4 GYPC CD236, CD236R, Ge, GPC, GYPD ENSG00000136732 Glycophorin C (Gerbich blood group) 2 126655933-126696675 Blood group antigen proteins, CD markers, Predicted membrane proteins Evidence at protein level HPA008965, CAB009445 Supported Approved Vesicles
Cytosol Expressed in all Expressed in all bone marrow: 230.3 GYS1 GSY, GYS ENSG00000104812 Glycogen synthase 1 (muscle) 19 48968125-48993310 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB007793, HPA041598 Supported Approved Microtubules
Cytosol Renal cancer:3.46e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 109.8 GZF1 dJ322G13.2, ZBTB23, ZNF336 ENSG00000125812 GDNF-inducible zinc finger protein 1 20 23362182-23373063 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024520 Uncertain Supported Nucleus
Nucleoli Liver cancer:9.81e-7 (unfavourable) Expressed in all Expressed in all adrenal gland: 25.5 H1F0 H10, H1FV ENSG00000189060 H1 histone family, member 0 22 37805093-37807436 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000843 Supported Supported Nucleus
Nuclear bodies
Golgi apparatus
Actin filaments Renal cancer:7.68e-7 (favourable) Expressed in all Expressed in all bone marrow: 420.8 H2AFJ FLJ10903, MGC921 ENSG00000246705 H2A histone family, member J 12 14774383-14778002 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041189 Supported Expressed in all Expressed in all testis: 335.4 H2AFV H2AV, MGC10170, MGC10831, MGC1947 ENSG00000105968 H2A histone family, member V 7 44826791-44848083 Predicted intracellular proteins Evidence at protein level HPA057236 Supported Cervical cancer:4.66e-4 (favourable), Renal cancer:8.04e-4 (favourable) Expressed in all Expressed in all bone marrow: 219.0 H2AFX H2AX ENSG00000188486 H2A histone family, member X 11 119093854-119095467 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012264, HPA041189, HPA051647 Supported Supported Nucleoplasm
Nuclear speckles Renal cancer:5.47e-9 (unfavourable), Liver cancer:1.51e-4 (unfavourable) Expressed in all Expressed in all lymph node: 18.9 H2AFY macroH2A1.2 ENSG00000113648 H2A histone family, member Y 5 135333900-135399914 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041189, HPA050962 Supported Supported Nucleus Liver cancer:2.89e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 155.9 H2AFY2 macroH2A2 ENSG00000099284 H2A histone family, member Y2 10 70052796-70112280 Predicted intracellular proteins Evidence at protein level HPA035865, HPA041189 Supported Validated Nucleoplasm Expressed in all Expressed in all endometrium: 31.3 H2AFZ H2A.Z, H2AZ ENSG00000164032 H2A histone family, member Z 4 99948086-99950388 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022549, HPA057236 Supported Supported Nucleoplasm Renal cancer:2.16e-6 (unfavourable), Liver cancer:1.02e-5 (unfavourable) Expressed in all Expressed in all lymph node: 354.3 H3F3A H3.3A, H3F3 ENSG00000163041 H3 histone, family 3A 1 226061851-226072001 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011481, CAB037178, HPA042570 Supported Supported Nucleoplasm Renal cancer:1.21e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 1218.1 H3F3B H3.3B ENSG00000132475 H3 histone, family 3B (H3.3B) 17 75776434-75785893 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB037166, CAB037187, CAB037221, HPA042570 Supported Validated Nucleoplasm Expressed in all Expressed in all bone marrow: 2838.4 H6PD GDH ENSG00000049239 Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1 9234775-9271337 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA004824, HPA005440 Approved Uncertain Cytosol Expressed in all Expressed in all ovary,skin: 42.7 HABP4 IHABP4, SERBP1L ENSG00000130956 Hyaluronan binding protein 4 9 96450201-96491336 Predicted intracellular proteins Evidence at protein level HPA055969 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.10e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 74.0 HACD2 PTPLB ENSG00000206527 3-hydroxyacyl-CoA dehydratase 2 3 123490820-123585185 Enzymes, Predicted membrane proteins Evidence at protein level CAB019282 Approved Pancreatic cancer:9.59e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 68.9 HACD3 B-ind1, HSPC121, PTPLAD1 ENSG00000074696 3-hydroxyacyl-CoA dehydratase 3 15 65530418-65578352 Enzymes, Predicted membrane proteins Evidence at protein level HPA014837, HPA060347 Approved Validated Nuclear membrane
Endoplasmic reticulum
Mitochondria
Cytosol Renal cancer:3.09e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 139.3 HACL1 2-HPCL, HPCL, PHYH2 ENSG00000131373 2-hydroxyacyl-CoA lyase 1 3 15560704-15601852 Predicted intracellular proteins Evidence at protein level HPA035496, HPA035497, HPA073760 Approved Supported Vesicles Renal cancer:2.63e-5 (favourable) Expressed in all Expressed in all duodenum: 52.3 HADH HADH1, HADHSC, SCHAD ENSG00000138796 Hydroxyacyl-CoA dehydrogenase 4 107989714-108035175 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039588, HPA043888 Supported Supported Mitochondria Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all kidney: 188.7 HADHA GBP, LCEH, LCHAD, MTPA ENSG00000084754 Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 2 26190635-26244726 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015536, HPA056070 Approved Validated Mitochondria Renal cancer:3.68e-5 (favourable) Expressed in all Expressed in all duodenum: 241.8 HADHB MTPB ENSG00000138029 Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2 26243170-26290468 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037539, HPA037540, HPA066099 Supported Supported Mitochondria Renal cancer:1.37e-9 (favourable) Expressed in all Expressed in all heart muscle: 313.2 HAGH GLO2, GLXII, HAGH1 ENSG00000063854 Hydroxyacylglutathione hydrolase 16 1795620-1827194 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043041, HPA061143 Approved Renal cancer:1.81e-6 (favourable), Liver cancer:5.33e-6 (favourable), Cervical cancer:5.82e-5 (favourable), Urothelial cancer:5.19e-4 (favourable) Expressed in all Expressed in all liver: 124.1 HARS ENSG00000170445 Histidyl-tRNA synthetase 5 140673173-140692024 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036539 Approved Validated Cytosol Liver cancer:1.96e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 71.3 HARS2 HARSL, HARSR, HO3 ENSG00000112855 Histidyl-tRNA synthetase 2, mitochondrial 5 140691426-140699291 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA035941 Approved Approved Cytosol Liver cancer:2.92e-4 (unfavourable), Colorectal cancer:6.19e-4 (favourable), Breast cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.8 HAT1 KAT1 ENSG00000128708 Histone acetyltransferase 1 2 171922448-171983682 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036788, CAB037191 Supported Validated Nucleoplasm Liver cancer:5.72e-5 (unfavourable) Expressed in all Expressed in all lymph node: 57.0 HAUS1 CCDC5, FLJ40084, HEI-C, HsT1461 ENSG00000152240 HAUS augmin-like complex, subunit 1 18 46104332-46128333 Predicted intracellular proteins Evidence at protein level HPA040601, HPA040652 Supported Supported Cytosol Ovarian cancer:1.55e-4 (favourable), Liver cancer:2.45e-4 (unfavourable), Prostate cancer:6.76e-4 (unfavourable) Expressed in all Expressed in all epididymis: 40.4 HAUS2 C15orf25, CEP27, FLJ10460, HsT17025 ENSG00000137814 HAUS augmin-like complex, subunit 2 15 42548810-42569994 Predicted intracellular proteins Evidence at protein level HPA039965 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all bone marrow: 22.5 HAUS3 C4orf15, dgt3, IT1, MGC4701 ENSG00000214367 HAUS augmin-like complex, subunit 3 4 2227464-2242164 Predicted intracellular proteins Evidence at protein level HPA040649, HPA048190 Approved Approved Microtubules
Mitochondria Urothelial cancer:4.78e-5 (favourable) Expressed in all Expressed in all bone marrow: 31.9 HAUS4 C14orf94, FLJ20424 ENSG00000092036 HAUS augmin-like complex, subunit 4 14 22946228-22957161 Predicted intracellular proteins Evidence at protein level HPA029803, HPA071195 Approved Supported Plasma membrane
Focal adhesion sites Urothelial cancer:2.24e-4 (unfavourable) Expressed in all Expressed in all ovary: 61.7 HAX1 HCLSBP1, HS1BP1 ENSG00000143575 HCLS1 associated protein X-1 1 154272511-154275875 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055141, HPA075289 Approved Supported Mitochondria Renal cancer:1.34e-5 (unfavourable) Expressed in all Expressed in all testis: 114.3 HBEGF DTR, DTS, HEGFL ENSG00000113070 Heparin-binding EGF-like growth factor 5 140332843-140346631 Predicted membrane proteins Evidence at protein level HPA053243 Uncertain Head and neck cancer:2.41e-4 (unfavourable), Prostate cancer:6.00e-4 (favourable), Pancreatic cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 89.2 HBP1 ENSG00000105856 HMG-box transcription factor 1 7 107168961-107202529 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020225, CAB032824 Approved Validated Nuclear speckles Renal cancer:7.70e-5 (favourable) Expressed in all Expressed in all thyroid gland: 108.7 HBS1L DKFZp434g247, EF-1a, eRF3c, ERFS, HBS1, HSPC276, KIAA1038 ENSG00000112339 HBS1-like translational GTPase 6 134960378-135103056 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029728, HPA029729 Approved Approved Nuclear bodies
Cytosol Colorectal cancer:6.77e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 73.4 HCCS CCHL, MLS ENSG00000004961 Holocytochrome c synthase X 11111301-11123078 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA002946 Approved Validated Mitochondria Renal cancer:6.17e-8 (favourable), Liver cancer:1.35e-5 (unfavourable), Breast cancer:8.69e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 31.9 HCFC1 CFF, HCF-1, HCF1, HFC1, MGC70925, MRX3, PPP1R89, VCAF ENSG00000172534 Host cell factor C1 X 153947553-153971807 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018312 Supported Nucleoplasm
Mitochondria Liver cancer:4.31e-6 (unfavourable), Pancreatic cancer:9.62e-5 (favourable) Expressed in all Expressed in all bone marrow: 24.7 HCFC1R1 FLJ20568, HPIP ENSG00000103145 Host cell factor C1 regulator 1 (XPO1 dependent) 16 3022620-3024286 Predicted intracellular proteins Evidence at protein level HPA059647 Approved Approved Nucleoplasm Expressed in all Expressed in all skeletal muscle: 184.4 HCFC2 HCF-2 ENSG00000111727 Host cell factor C2 12 104064457-104106524 Predicted intracellular proteins Evidence at protein level HPA006227 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 17.0 HCLS1 CTTNL, HS1 ENSG00000180353 Hematopoietic cell-specific Lyn substrate 1 3 121631399-121660927 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019143 Supported Supported Plasma membrane
Cytosol Expressed in all Expressed in all spleen: 275.8 HCST DAP10, DKFZP586C1522, KAP10, PIK3AP ENSG00000126264 Hematopoietic cell signal transducer 19 35902480-35904377 Predicted membrane proteins Evidence at protein level CAB034435, HPA063026 Supported Uncertain Vesicles Renal cancer:1.59e-10 (unfavourable), Melanoma:6.70e-4 (favourable) Expressed in all Expressed in all bone marrow: 154.7 HDAC1 GON-10, HD1, RPD3L1 ENSG00000116478 Histone deacetylase 1 1 32292086-32333635 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005017, HPA029693, CAB068191 Supported Validated Nucleoplasm Liver cancer:5.76e-7 (unfavourable), Renal cancer:1.04e-5 (unfavourable) Expressed in all Expressed in all lymph node: 140.7 HDAC2 RPD3, YAF1 ENSG00000196591 Histone deacetylase 2 6 113933028-114011308 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005054, HPA011727 Supported Validated Nucleus Liver cancer:5.39e-10 (unfavourable), Breast cancer:7.07e-4 (unfavourable) Expressed in all Expressed in all testis: 142.0 HDAC3 HD3, RPD3, RPD3-2 ENSG00000171720 Histone deacetylase 3 5 141620876-141636870 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB005583, HPA052052 Supported Supported Nucleoplasm
Golgi apparatus Renal cancer:2.65e-6 (unfavourable), Colorectal cancer:3.39e-4 (favourable), Pancreatic cancer:3.95e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.1 HDAC5 FLJ90614, KIAA0600, NY-CO-9 ENSG00000108840 Histone deacetylase 5 17 44076746-44123702 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB019400, HPA030991 Approved Supported Nuclear speckles
Golgi apparatus
Cytosol Liver cancer:3.12e-5 (unfavourable), Renal cancer:3.30e-5 (favourable), Cervical cancer:6.14e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 59.2 HDAC6 FLJ16239, HD6, JM21, KIAA0901, PPP1R90 ENSG00000094631 Histone deacetylase 6 X 48801377-48824982 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA003714, CAB004236, HPA026321 Approved Supported Nucleoplasm Urothelial cancer:3.34e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 50.4 HDAC7 DKFZP586J0917, HDAC7A ENSG00000061273 Histone deacetylase 7 12 47782722-47833132 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004775 Supported Cytosol Urothelial cancer:4.65e-4 (favourable), Melanoma:5.16e-4 (unfavourable), Renal cancer:8.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.9 HDAC8 HDACL1, MRXS6, RPD3, WTS ENSG00000147099 Histone deacetylase 8 X 72329516-72573103 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048560 Supported Supported Nucleus
Plasma membrane Expressed in all Expressed in all epididymis: 26.9 HDDC2 C6orf74, CGI-130, dJ167O5.2 ENSG00000111906 HD domain containing 2 6 125219962-125302078 Predicted intracellular proteins Evidence at protein level HPA035677 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all testis: 116.6 HDDC3 MGC45386 ENSG00000184508 HD domain containing 3 15 90929964-90932569 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040895 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all adrenal gland: 16.3 HDGF HMG1L2 ENSG00000143321 Hepatoma-derived growth factor 1 156742107-156766925 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026035, HPA048728, HPA053422 Supported Validated Nucleoplasm Liver cancer:2.43e-8 (unfavourable), Endometrial cancer:6.02e-4 (unfavourable), Ovarian cancer:9.84e-4 (favourable) Expressed in all Expressed in all bone marrow: 190.7 HDHD2 DKFZP564D1378 ENSG00000167220 Haloacid dehalogenase-like hydrolase domain containing 2 18 47107403-47150520 Predicted intracellular proteins Evidence at protein level HPA040697, CAB045978, HPA059818 Approved Approved Vesicles Renal cancer:3.52e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 49.0 HDHD3 C9orf158, MGC12904 ENSG00000119431 Haloacid dehalogenase-like hydrolase domain containing 3 9 113373419-113376999 Predicted intracellular proteins Evidence at protein level HPA020427, HPA024158, HPA024585 Approved Supported Nucleoli Renal cancer:3.54e-7 (favourable), Cervical cancer:2.72e-4 (favourable) Expressed in all Expressed in all adrenal gland: 87.2 HDLBP HBP, VGL ENSG00000115677 High density lipoprotein binding protein 2 241227264-241317061 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004189, CAB026457 Supported Supported Cytosol Liver cancer:2.58e-5 (unfavourable), Thyroid cancer:6.39e-5 (unfavourable), Urothelial cancer:4.12e-4 (unfavourable) Expressed in all Expressed in all testis: 364.5 HEATR1 BAP28, FLJ10359, UTP10 ENSG00000119285 HEAT repeat containing 1 1 236549005-236604504 Predicted intracellular proteins Evidence at protein level HPA046917, HPA062200 Approved Validated Nucleoli fibrillar center
Mitochondria Liver cancer:2.05e-4 (unfavourable), Renal cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all testis: 26.9 HEATR5A C14orf125, DKFZP434I1735 ENSG00000129493 HEAT repeat containing 5A 14 31291791-31420582 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA049539 Uncertain Renal cancer:1.11e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 17.9 HEATR5B DKFZp686P15184, KIAA1414 ENSG00000008869 HEAT repeat containing 5B 2 36968383-37084342 Predicted intracellular proteins Evidence at protein level HPA042025, HPA055639 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 38.4 HEBP1 HBP, HEBP ENSG00000013583 Heme binding protein 1 12 12974864-13000273 Predicted intracellular proteins Evidence at protein level HPA056417, HPA075277 Approved Approved Nucleus
Vesicles Expressed in all Expressed in all duodenum: 241.2 HEBP2 C6orf34, SOUL ENSG00000051620 Heme binding protein 2 6 138403531-138422197 Predicted intracellular proteins Evidence at protein level HPA016928 Approved Renal cancer:2.47e-5 (unfavourable), Urothelial cancer:3.07e-4 (favourable) Expressed in all Expressed in all adipose tissue: 113.9 HECA dJ225E12.1, HDC, HDCL, hHDC ENSG00000112406 Hdc homolog, cell cycle regulator 6 139135112-139180802 Predicted intracellular proteins Evidence at protein level HPA042313 Uncertain Renal cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all spleen: 38.7 HECTD1 KIAA1131 ENSG00000092148 HECT domain containing E3 ubiquitin protein ligase 1 14 31100112-31207804 Predicted intracellular proteins Evidence at protein level HPA002929, HPA054461 Approved Supported Nucleus
Nucleoli Renal cancer:1.20e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 107.5 HECTD3 FLJ21156 ENSG00000126107 HECT domain containing E3 ubiquitin protein ligase 3 1 45002540-45011329 Predicted intracellular proteins Evidence at protein level HPA027467 Approved Thyroid cancer:1.85e-6 (favourable), Liver cancer:2.14e-5 (unfavourable) Expressed in all Expressed in all duodenum: 48.6 HECTD4 C12orf51, FLJ34154, KIAA0614 ENSG00000173064 HECT domain containing E3 ubiquitin protein ligase 4 12 112160188-112382439 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041062, HPA045473 Uncertain Approved Nucleoplasm
Vesicles Head and neck cancer:2.97e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 19.4 HELZ DHRC, HUMORF5, KIAA0054 ENSG00000198265 Helicase with zinc finger 17 67070438-67245989 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028276 Approved Approved Nucleoli
Plasma membrane
Actin filaments Expressed in all Expressed in all parathyroid gland: 32.3 HEMK1 MTQ1 ENSG00000114735 HemK methyltransferase family member 1 3 50569152-50596168 Predicted intracellular proteins Evidence at protein level HPA034701, HPA034702 Uncertain Expressed in all Expressed in all parathyroid gland: 31.6 HERC1 p532, p619 ENSG00000103657 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 15 63608618-63833942 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049749 Uncertain Renal cancer:1.36e-6 (favourable), Head and neck cancer:4.87e-5 (favourable), Pancreatic cancer:3.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 57.5 HERC3 KIAA0032 ENSG00000138641 HECT and RLD domain containing E3 ubiquitin protein ligase 3 4 88521048-88708542 Predicted intracellular proteins Evidence at protein level HPA039170 Approved Approved Cytosol Renal cancer:5.65e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 59.9 HERC4 DKFZP564G092, KIAA1593 ENSG00000148634 HECT and RLD domain containing E3 ubiquitin protein ligase 4 10 67921899-68075348 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045453, HPA070301 Uncertain Supported Nucleoli fibrillar center
Cytosol Renal cancer:3.86e-5 (unfavourable) Expressed in all Expressed in all testis: 32.4 HERC6 FLJ20637 ENSG00000138642 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4 88378739-88443111 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035846 Uncertain Supported Nucleus
Cytosol Renal cancer:7.14e-5 (favourable) Expressed in all Expressed in all esophagus: 22.9 HERPUD1 HERP, KIAA0025, Mif1, SUP ENSG00000051108 Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 16 56932048-56944863 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB037041, CAB037104, HPA040754, HPA041219 Approved Uncertain Plasma membrane
Cytosol Renal cancer:1.41e-9 (favourable) Expressed in all Expressed in all prostate: 379.0 HERPUD2 FLJ22313 ENSG00000122557 HERPUD family member 2 7 35632659-35695571 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015630, HPA076087 Approved Approved Nucleoli Expressed in all Expressed in all testis: 51.6 HEXA ENSG00000213614 Hexosaminidase A (alpha polypeptide) 15 72340919-72376476 Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA054583 Supported Endometrial cancer:5.63e-8 (favourable) Expressed in all Expressed in all epididymis: 197.5 HEXB ENSG00000049860 Hexosaminidase B (beta polypeptide) 5 74640023-74722647 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA055409, HPA056010 Approved Liver cancer:3.36e-8 (unfavourable) Expressed in all Expressed in all placenta: 437.6 HEXDC FLJ23825 ENSG00000169660 Hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 17 82418318-82442645 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022834, HPA023379, HPA027844 Uncertain Approved Nucleoli fibrillar center
Mitochondria Urothelial cancer:2.52e-5 (favourable), Head and neck cancer:2.71e-4 (favourable), Pancreatic cancer:5.57e-4 (favourable), Cervical cancer:7.70e-4 (favourable) Expressed in all Expressed in all spleen: 25.9 HEXIM1 CLP-1, EDG1, HIS1, MAQ1 ENSG00000186834 Hexamethylene bis-acetamide inducible 1 17 45148502-45152101 Predicted intracellular proteins Evidence at protein level HPA008926, CAB011625 Supported Validated Nucleoplasm
Vesicles Expressed in all Expressed in all placenta: 36.5 HEXIM2 FLJ32384 ENSG00000168517 Hexamethylene bis-acetamide inducible 2 17 45160700-45170040 Predicted intracellular proteins Evidence at protein level HPA023323, HPA028455 Supported Supported Nucleoplasm
Nuclear speckles Endometrial cancer:2.53e-4 (favourable), Ovarian cancer:9.85e-4 (favourable) Expressed in all Expressed in all testis: 46.8 HGS Hrs, Vps27, ZFYVE8 ENSG00000185359 Hepatocyte growth factor-regulated tyrosine kinase substrate 17 81683326-81703138 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004872, HPA007728 Uncertain Validated Endosomes
Lysosomes
Cytosol Renal cancer:4.31e-7 (unfavourable), Liver cancer:5.61e-5 (unfavourable), Cervical cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all skin: 85.0 HGSNAT FLJ32731, HGNAT, TMEM76 ENSG00000165102 Heparan-alpha-glucosaminide N-acetyltransferase 8 43140455-43202855 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA029578 Approved Ovarian cancer:6.33e-5 (favourable), Glioma:7.02e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.4 HHEX HEX, HOX11L-PEN, PRHX ENSG00000152804 Hematopoietically expressed homeobox 10 92689951-92695646 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051894, HPA055460 Approved Approved Nucleoplasm
Mitochondria Renal cancer:3.25e-5 (unfavourable), Cervical cancer:3.91e-5 (favourable), Liver cancer:6.23e-4 (unfavourable), Breast cancer:8.83e-4 (favourable) Expressed in all Expressed in all thyroid gland: 163.9 HIAT1 DKFZP564L0864 ENSG00000156875 Hippocampus abundant transcript 1 1 100038097-100083377 Predicted membrane proteins Evidence at transcript level HPA073681 Approved Vesicles Liver cancer:2.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 197.2 HIATL1 FLJ14753 ENSG00000148110 Hippocampus abundant transcript-like 1 9 94374551-94461042 Predicted membrane proteins, Transporters Evidence at protein level HPA017978 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 251.1 HIBADH NS5ATP1 ENSG00000106049 3-hydroxyisobutyrate dehydrogenase 7 27525442-27662995 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA019522, HPA021002 Supported Renal cancer:5.56e-11 (favourable) Expressed in all Expressed in all kidney: 112.0 HIBCH ENSG00000198130 3-hydroxyisobutyryl-CoA hydrolase 2 190189735-190344193 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036540, HPA036541 Supported Approved Nucleoplasm
Mitochondria Renal cancer:1.04e-10 (favourable), Ovarian cancer:1.22e-4 (favourable) Expressed in all Expressed in all kidney: 183.7 HID1 C17orf28, DMC1, HID-1 ENSG00000167861 HID1 domain containing 17 74950743-74973166 Predicted intracellular proteins Evidence at protein level HPA023095, HPA031406 Approved Supported Golgi apparatus
Cytosol Renal cancer:3.13e-5 (favourable), Urothelial cancer:1.34e-4 (favourable) Expressed in all Expressed in all stomach: 54.0 HIF1A bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8 ENSG00000100644 Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 14 61695513-61748259 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000907, HPA001275, CAB017442 Supported Supported Nucleoplasm
Nuclear bodies
Plasma membrane Expressed in all Expressed in all bone marrow: 292.9 HIF1AN DKFZp762F1811, FIH1, FLJ20615, FLJ22027 ENSG00000166135 Hypoxia inducible factor 1, alpha subunit inhibitor 10 100529072-100559998 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048742, HPA065302, CAB069903 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 25.7 HIGD1A DKFZP564K247, HIG1 ENSG00000181061 HIG1 hypoxia inducible domain family, member 1A 3 42784298-42804531 Predicted membrane proteins Evidence at protein level HPA043336 Approved Supported Nucleoplasm
Mitochondria Renal cancer:3.99e-8 (favourable), Colorectal cancer:2.12e-4 (favourable) Expressed in all Expressed in all rectum: 333.6 HIGD2A MGC2198 ENSG00000146066 HIG1 hypoxia inducible domain family, member 2A 5 176388747-176389771 Predicted membrane proteins Evidence at protein level HPA042715 Uncertain Supported Mitochondria
Cytosol Liver cancer:9.47e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 168.2 HILPDA C7orf68, FLJ21076, HIG-2, HIG2 ENSG00000135245 Hypoxia inducible lipid droplet-associated 7 128455849-128458418 Predicted membrane proteins Evidence at protein level HPA010515 Approved Supported Nucleoplasm
Lipid droplets Liver cancer:4.30e-11 (unfavourable), Renal cancer:2.05e-7 (unfavourable) Expressed in all Expressed in all esophagus: 108.2 HINFP DKFZP434F162, HiNF-P, MIZF, ZNF743 ENSG00000172273 Histone H4 transcription factor 11 119121587-119136044 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059053, HPA061008 Uncertain Supported Nucleus
Cell Junctions
Cytosol Liver cancer:4.44e-8 (unfavourable), Thyroid cancer:5.26e-4 (favourable) Expressed in all Expressed in all testis: 12.0 HINT1 HINT, PKCI-1, PRKCNH1 ENSG00000169567 Histidine triad nucleotide binding protein 1 5 131159027-131171735 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044577 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 174.4 HINT2 ENSG00000137133 Histidine triad nucleotide binding protein 2 9 35812960-35815354 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA020961, HPA059109 Supported Validated Mitochondria Renal cancer:2.97e-9 (favourable), Ovarian cancer:1.66e-4 (favourable) Expressed in all Expressed in all kidney: 82.4 HINT3 FLJ33126 ENSG00000111911 Histidine triad nucleotide binding protein 3 6 125956781-125980244 Predicted intracellular proteins Evidence at protein level HPA027914 Approved Supported Nucleoli
Mitochondria
Cytosol Renal cancer:1.05e-6 (favourable), Breast cancer:4.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 49.8 HIP1R FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655 ENSG00000130787 Huntingtin interacting protein 1 related 12 122834453-122862960 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB017187, HPA038135, HPA038136 Approved Validated Vesicles
Plasma membrane
Cytosol Renal cancer:6.50e-7 (favourable), Urothelial cancer:7.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 53.3 HIPK1 KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2 ENSG00000163349 Homeodomain interacting protein kinase 1 1 113929192-113977869 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016664 Approved Approved Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all bone marrow: 89.9 HIPK2 ENSG00000064393 Homeodomain interacting protein kinase 2 7 139561570-139777778 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA007611 Supported Supported Nucleus Renal cancer:9.99e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 61.5 HIPK3 DYRK6, FIST3, PKY, YAK1 ENSG00000110422 Homeodomain interacting protein kinase 3 11 33256672-33357023 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028069 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all parathyroid gland: 124.8 HIRA DGCR1, TUP1, TUPLE1 ENSG00000100084 Histone cell cycle regulator 22 19330698-19447450 Predicted intracellular proteins Evidence at protein level CAB039243, CAB039244, HPA050714, HPA052902 Supported Validated Nucleoplasm Renal cancer:5.18e-6 (favourable), Pancreatic cancer:3.97e-4 (favourable), Ovarian cancer:8.11e-4 (favourable) Expressed in all Expressed in all thyroid gland: 93.6 HIRIP3 ENSG00000149929 HIRA interacting protein 3 16 29992321-29996436 Predicted intracellular proteins Evidence at protein level HPA051897, HPA063205 Approved Validated Nucleus Cervical cancer:2.74e-5 (favourable) Expressed in all Expressed in all testis: 39.1 HIST1H1C H1.2, H1c, H1F2, H1s-1 ENSG00000187837 Histone cluster 1, H1c 6 26055787-26056428 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011507, HPA055907 Supported Supported Nucleus
Nucleoli Urothelial cancer:8.06e-5 (favourable), Pancreatic cancer:1.12e-4 (unfavourable), Renal cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 185.5 HIST1H2AC H2AFL ENSG00000180573 Histone cluster 1, H2ac 6 26124145-26139116 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA041189 Supported Expressed in all Expressed in all prostate: 56.2 HIST1H2BD H2B/b, H2BFB ENSG00000158373 Histone cluster 1, H2bd 6 26158146-26171349 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671, CAB062336 Supported Approved Nucleoplasm
Cytosol Colorectal cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all prostate: 84.8 HIST1H2BK H2BFAiii, H2BFT ENSG00000197903 Histone cluster 1, H2bk 6 27146418-27146798 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Renal cancer:5.77e-5 (unfavourable) Expressed in all Expressed in all prostate: 96.7 HIST2H2BE H2B, H2B.1, H2B/q, H2BFQ ENSG00000184678 Histone cluster 2, H2be 1 149842204-149886652 Predicted intracellular proteins Evidence at protein level HPA042205, HPA043013, HPA048671 Supported Approved Nucleoplasm
Cytosol Colorectal cancer:2.90e-4 (unfavourable) Expressed in all Expressed in all prostate: 112.0 HIVEP2 HIV-EP2, MBP-2, MIBP1, Schnurri-2, ZAS2, ZNF40B ENSG00000010818 Human immunodeficiency virus type I enhancer binding protein 2 6 142751467-142945201 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055954 Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 31.5 HK1 ENSG00000156515 Hexokinase 1 10 69269984-69401882 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007043, HPA007044, CAB010052, HPA011956 Supported Validated Mitochondria Head and neck cancer:3.39e-6 (unfavourable) Expressed in all Expressed in all testis: 152.9 HKR1 ZNF875 ENSG00000181666 HKR1, GLI-Kruppel zinc finger family member 19 37312837-37369365 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036126, HPA044855 Approved Supported Nucleoplasm
Golgi apparatus
Mitochondria Prostate cancer:5.18e-5 (unfavourable), Pancreatic cancer:4.41e-4 (favourable) Expressed in all Expressed in all thyroid gland: 54.4 HLA-DPA1 HLA-DP1A ENSG00000231389 Major histocompatibility complex, class II, DP alpha 1 6 33064569-33080775 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017967 Supported Supported Vesicles Expressed in all Expressed in all lung: 122.4 HLA-DPB1 HLA-DP1B ENSG00000223865 Major histocompatibility complex, class II, DP beta 1 6 33075926-33087201 Predicted membrane proteins Evidence at protein level HPA011078, HPA058509 Approved Approved Nucleus
Cell Junctions Endometrial cancer:3.38e-4 (favourable) Expressed in all Expressed in all spleen: 174.2 HLCS HCS ENSG00000159267 Holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 21 36750888-36990236 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017379 Approved Supported Cytosol Breast cancer:7.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.1 HLTF HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3 ENSG00000071794 Helicase-like transcription factor 3 149030127-149086554 Predicted intracellular proteins Evidence at protein level HPA015284, HPA049001 Uncertain Validated Nucleus Liver cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all testis: 83.0 HM13 dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1 ENSG00000101294 Histocompatibility (minor) 13 20 31514428-31577923 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA045089, HPA056062 Approved Supported Endoplasmic reticulum Renal cancer:4.64e-12 (unfavourable), Liver cancer:1.95e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 153.3 HMCES C3orf37, DC12, SRAPD1 ENSG00000183624 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 3 129278828-129306186 Predicted intracellular proteins Evidence at protein level HPA044968 Approved Approved Nucleus Liver cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 201.5 HMG20A FLJ10739, HMGX1, HMGXB1 ENSG00000140382 High mobility group 20A 15 77420412-77485607 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008126 Supported Approved Nucleus Expressed in all Expressed in all spleen: 49.8 HMG20B BRAF25, BRAF35, HMGX2, HMGXB2, SMARCE1r, SOXL ENSG00000064961 High mobility group 20B 19 3572777-3579088 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050220, HPA053157, HPA069832 Approved Validated Nucleoplasm Endometrial cancer:1.72e-7 (favourable), Urothelial cancer:2.89e-5 (favourable) Expressed in all Expressed in all prostate: 64.9 HMGA1 HMGIY ENSG00000137309 High mobility group AT-hook 1 6 34236873-34246231 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB032200 Uncertain Approved Nucleus
Nucleoli Liver cancer:1.29e-6 (unfavourable), Lung cancer:3.36e-4 (unfavourable), Endometrial cancer:7.13e-4 (unfavourable), Pancreatic cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all lymph node: 165.8 HMGB1 DKFZp686A04236, HMG1, HMG3, SBP-1 ENSG00000189403 High mobility group box 1 13 30456704-30617597 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003506, CAB005873 Supported Supported Nucleus Expressed in all Expressed in all lymph node: 792.0 HMGB2 HMG2 ENSG00000164104 High mobility group box 2 4 173331695-173335125 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003506, CAB037206, HPA053314 Supported Supported Nucleus
Nucleoli Renal cancer:7.60e-12 (unfavourable), Liver cancer:3.76e-5 (unfavourable), Melanoma:3.13e-4 (unfavourable), Pancreatic cancer:7.04e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 1466.9 HMGB3 HMG2A, HMG4, MGC90319 ENSG00000029993 High mobility group box 3 X 150980509-150990775 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062583 Supported Approved Nucleus
Nucleoli Ovarian cancer:9.85e-5 (favourable), Renal cancer:6.15e-4 (favourable) Expressed in all Expressed in all placenta: 195.7 HMGCL HL ENSG00000117305 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1 23801885-23838620 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004727 Supported Renal cancer:5.07e-8 (favourable), Colorectal cancer:7.67e-4 (favourable) Expressed in all Expressed in all liver: 153.9 HMGCR ENSG00000113161 3-hydroxy-3-methylglutaryl-CoA reductase 5 75336329-75362104 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008338, CAB016797 Approved Renal cancer:9.42e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 87.8 HMGCS1 HMGCS ENSG00000112972 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 5 43289395-43313512 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032907, HPA036913, HPA036914 Approved Supported Nucleus
Plasma membrane
Cytosol Renal cancer:3.87e-6 (favourable) Expressed in all Expressed in all liver: 208.6 HMGN1 FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425 ENSG00000205581 High mobility group nucleosome binding domain 1 21 39342315-39349647 Predicted intracellular proteins Evidence at protein level CAB012260, HPA048694 Supported Supported Nucleus Renal cancer:8.74e-7 (unfavourable) Expressed in all Expressed in all tonsil: 227.6 HMGN2 HMG17 ENSG00000198830 High mobility group nucleosomal binding domain 2 1 26472450-26475972 Predicted intracellular proteins Evidence at protein level CAB018371, HPA077364 Supported Supported Nucleus Liver cancer:1.34e-4 (unfavourable), Renal cancer:3.92e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 784.4 HMGN3 TRIP7 ENSG00000118418 High mobility group nucleosomal binding domain 3 6 79201245-79234738 Predicted intracellular proteins Evidence at protein level CAB018370, HPA027971 Supported Validated Nucleus
Cytosol Renal cancer:1.02e-7 (unfavourable), Lung cancer:2.76e-4 (favourable) Expressed in all Expressed in all fallopian tube: 332.5 HMGN4 HMG17L3, NHC ENSG00000182952 High mobility group nucleosomal binding domain 4 6 26538405-26546254 Predicted intracellular proteins Evidence at protein level HPA077364 Uncertain Nucleus Expressed in all Expressed in all thyroid gland: 131.2 HMGN5 NSBP1 ENSG00000198157 High mobility group nucleosome binding domain 5 X 81113701-81201942 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000511 Approved Supported Nucleus Ovarian cancer:6.60e-4 (favourable) Expressed in all Expressed in all testis: 201.8 HMGXB4 HMG2L1, THC211630 ENSG00000100281 HMG box domain containing 4 22 35257452-35295807 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000725 Approved Colorectal cancer:3.24e-5 (favourable), Pancreatic cancer:1.16e-4 (unfavourable), Liver cancer:4.79e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.7 HMOX1 bK286B10, HO-1 ENSG00000100292 Heme oxygenase 1 22 35380361-35394214 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000635, CAB017444 Supported Uncertain Golgi apparatus
Plasma membrane Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all spleen: 435.2 HMOX2 HO-2 ENSG00000103415 Heme oxygenase 2 16 4474690-4510347 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025464, HPA040611 Supported Approved Vesicles
Cytosol Renal cancer:8.98e-6 (favourable), Endometrial cancer:7.91e-4 (favourable) Expressed in all Expressed in all testis: 97.3 HN1 ARM2, HN1A ENSG00000189159 Hematological and neurological expressed 1 17 75135248-75168281 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059729 Approved Supported Nucleus
Nuclear membrane
Nucleoli Liver cancer:1.58e-7 (unfavourable), Renal cancer:1.77e-7 (unfavourable), Ovarian cancer:4.91e-4 (favourable) Expressed in all Expressed in all testis: 421.3 HN1L C16orf34, FLJ13092, KIAA1426, L11 ENSG00000206053 Hematological and neurological expressed 1-like 16 1678256-1702280 Predicted intracellular proteins Evidence at protein level HPA041888, HPA041908 Approved Validated Plasma membrane
Cytosol Endometrial cancer:7.85e-4 (favourable), Liver cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 100.6 HNMT ENSG00000150540 Histamine N-methyltransferase 2 137964020-138016364 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035480, HPA035481 Approved Pancreatic cancer:3.41e-4 (unfavourable), Urothelial cancer:4.68e-4 (favourable) Expressed in all Expressed in all liver: 123.8 HNRNPA0 hnRNPA0, HNRPA0 ENSG00000177733 Heterogeneous nuclear ribonucleoprotein A0 5 137745651-137754376 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036569, HPA059404 Supported Validated Nucleoplasm Renal cancer:1.99e-4 (favourable), Pancreatic cancer:3.74e-4 (favourable) Expressed in all Expressed in all ovary: 32.7 HNRNPA1 ALS20, hnRNP-A1, hnRNPA1, HNRPA1 ENSG00000135486 Heterogeneous nuclear ribonucleoprotein A1 12 54280193-54287088 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001609, HPA001666, HPA005812, HPA007185, CAB010894 Supported Validated Nucleoplasm Expressed in all Expressed in all ovary: 1913.9 HNRNPA2B1 HNRPA2B1 ENSG00000122566 Heterogeneous nuclear ribonucleoprotein A2/B1 7 26189927-26201529 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001666, HPA005812, CAB012403, HPA065537 Supported Validated Nucleoplasm Liver cancer:1.03e-6 (unfavourable), Renal cancer:8.01e-5 (unfavourable), Prostate cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all lymph node: 762.7 HNRNPA3 HNRPA3 ENSG00000170144 Heterogeneous nuclear ribonucleoprotein A3 2 177212563-177223958 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001666, HPA005812, HPA066381 Supported Validated Nucleoplasm Renal cancer:9.57e-7 (unfavourable), Liver cancer:2.95e-5 (unfavourable), Cervical cancer:4.87e-4 (favourable) Expressed in all Expressed in all appendix: 316.2 HNRNPAB ABBP1, FLJ40338, HNRPAB ENSG00000197451 Heterogeneous nuclear ribonucleoprotein A/B 5 178204507-178211180 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046688 Approved Validated Nucleoplasm Renal cancer:1.35e-7 (unfavourable), Ovarian cancer:9.79e-4 (favourable) Expressed in all Expressed in all colon: 159.3 HNRNPC hnRNPC, HNRPC ENSG00000092199 Heterogeneous nuclear ribonucleoprotein C (C1/C2) 14 21209136-21269494 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005223, HPA051075, CAB075755, CAB075756 Supported Validated Nucleoplasm Renal cancer:7.29e-5 (unfavourable), Liver cancer:7.72e-5 (unfavourable), Ovarian cancer:1.19e-4 (favourable) Expressed in all Expressed in all lymph node: 576.3 HNRNPD AUF1, HNRPD ENSG00000138668 Heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 4 82352498-82374503 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004911 Supported Validated Nucleoplasm Expressed in all Expressed in all lymph node: 345.7 HNRNPDL HNRPDL, JKTBP, laAUF1 ENSG00000152795 Heterogeneous nuclear ribonucleoprotein D-like 4 82422564-82430408 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056820, HPA063147 Supported Validated Nucleoplasm Expressed in all Expressed in all endometrium: 420.2 HNRNPF HNRPF ENSG00000169813 Heterogeneous nuclear ribonucleoprotein F 10 43385617-43409166 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016884, HPA069667 Supported Validated Nucleoplasm Liver cancer:5.85e-4 (unfavourable) Expressed in all Expressed in all lymph node: 195.4 HNRNPH1 hnRNPH, HNRPH1 ENSG00000169045 Heterogeneous nuclear ribonucleoprotein H1 (H) 5 179614178-179634784 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000914, HPA001359, HPA016884, CAB032820 Supported Supported Nucleoplasm
Cytosol Liver cancer:3.29e-7 (unfavourable), Renal cancer:3.46e-4 (unfavourable), Head and neck cancer:7.85e-4 (favourable) Expressed in all Expressed in all lymph node: 220.8 HNRNPH2 FTP3, hnRNPH', HNRPH', HNRPH2 ENSG00000126945 Heterogeneous nuclear ribonucleoprotein H2 (H') X 101408295-101414133 Predicted intracellular proteins Evidence at protein level HPA000914, HPA001359, CAB004436, HPA016884 Supported Validated Nucleoplasm Renal cancer:7.37e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 212.9 HNRNPH3 2H9, HNRPH3 ENSG00000096746 Heterogeneous nuclear ribonucleoprotein H3 (2H9) 10 68331174-68343191 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038264 Supported Nucleoplasm Liver cancer:2.30e-5 (unfavourable) Expressed in all Expressed in all endometrium: 153.7 HNRNPK CSBP, HNRPK, TUNP ENSG00000165119 Heterogeneous nuclear ribonucleoprotein K 9 83968083-83980616 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004435, HPA007644, CAB016225, HPA044105 Supported Validated Nucleoplasm Liver cancer:6.68e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 518.7 HNRNPL HNRPL ENSG00000104824 Heterogeneous nuclear ribonucleoprotein L 19 38836388-38852347 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016326, HPA051748, HPA052661 Supported Validated Nucleoplasm Renal cancer:1.96e-11 (unfavourable), Liver cancer:3.25e-6 (unfavourable), Pancreatic cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 110.6 HNRNPLL HNRPLL ENSG00000143889 Heterogeneous nuclear ribonucleoprotein L-like 2 38561978-38603586 Predicted intracellular proteins Evidence at protein level HPA046084 Approved Approved Nucleus
Mitochondria
Cytosol Liver cancer:1.22e-4 (unfavourable) Expressed in all Expressed in all testis: 37.3 HNRNPM CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1 ENSG00000099783 Heterogeneous nuclear ribonucleoprotein M 19 8444767-8489114 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016113, HPA024344 Supported Validated Nucleoplasm Liver cancer:1.80e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 200.3 HNRNPR hnRNP-R, HNRPR ENSG00000125944 Heterogeneous nuclear ribonucleoprotein R 1 23303771-23344336 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011687, HPA026092 Supported Validated Nucleoplasm Liver cancer:1.32e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.7 HNRNPU hnRNPU, HNRPU, SAF-A ENSG00000153187 Heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 1 244851166-244864542 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011532, HPA041057, HPA058707 Supported Supported Nucleoplasm Liver cancer:8.88e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 216.8 HNRNPUL1 E1B-AP5, E1BAP5, FLJ12944, HNRPUL1 ENSG00000105323 Heterogeneous nuclear ribonucleoprotein U-like 1 19 41262496-41307598 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046290, CAB046477, HPA049475 Supported Validated Nucleoplasm Endometrial cancer:1.84e-5 (unfavourable) Expressed in all Expressed in all testis: 150.0 HNRNPUL2 DKFZp762N1910, HNRPUL2 ENSG00000214753 Heterogeneous nuclear ribonucleoprotein U-like 2 11 62712630-62727349 Predicted intracellular proteins Evidence at protein level HPA041632, HPA056696, HPA067699 Supported Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 59.4 HOMER2 CPD, Cupidin, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2 ENSG00000103942 Homer scaffolding protein 2 15 82836946-82986153 Predicted intracellular proteins Evidence at protein level HPA040134 Uncertain Supported Cytosol Mixed Expressed in all prostate: 90.8 HOMER3 HOMER-3 ENSG00000051128 Homer scaffolding protein 3 19 18929201-18941261 Predicted intracellular proteins Evidence at protein level CAB032656, HPA040999 Supported Supported Plasma membrane
Cytosol
Cytoplasmic bodies Colorectal cancer:4.24e-5 (unfavourable), Liver cancer:4.93e-5 (unfavourable) Expressed in all Expressed in all spleen: 153.4 HOMEZ KIAA1443 ENSG00000215271 Homeobox and leucine zipper encoding 14 23272422-23299447 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036316, HPA036317 Approved Supported Nucleus
Nucleoli Renal cancer:1.17e-11 (favourable), Ovarian cancer:2.41e-5 (favourable), Thyroid cancer:1.75e-4 (favourable) Expressed in all Expressed in all testis: 41.5 HOOK2 HK2 ENSG00000095066 Hook microtubule-tethering protein 2 19 12763003-12872740 Predicted intracellular proteins Evidence at protein level HPA043519, HPA050351 Approved Supported Vesicles
Cytosol Prostate cancer:7.59e-5 (unfavourable), Renal cancer:3.28e-4 (favourable) Expressed in all Expressed in all thyroid gland: 95.9 HP1BP3 HP1-BP74 ENSG00000127483 Heterochromatin protein 1, binding protein 3 1 20742661-20787323 Predicted intracellular proteins Evidence at protein level HPA028215, HPA054295 Supported Supported Nuclear speckles Liver cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all endometrium: 191.2 HPCAL1 BDR1, HLP2, VILIP-3 ENSG00000115756 Hippocalcin-like 1 2 10302889-10427617 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043245 Approved Renal cancer:4.39e-6 (unfavourable), Glioma:5.68e-5 (unfavourable) Expressed in all Expressed in all lung: 80.8 HPRT1 HGPRT, HPRT ENSG00000165704 Hypoxanthine phosphoribosyltransferase 1 X 134460153-134520513 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006360, CAB012200 Supported Supported Cytosol Head and neck cancer:1.35e-5 (unfavourable) Expressed in all Expressed in all testis: 138.3 HPS1 BLOC3S1, HPS ENSG00000107521 Hermansky-Pudlak syndrome 1 10 98416198-98446947 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA061260 Approved Endometrial cancer:2.93e-5 (favourable), Cervical cancer:3.37e-5 (favourable), Lung cancer:1.26e-4 (favourable), Glioma:5.53e-4 (unfavourable) Expressed in all Expressed in all lymph node: 24.6 HPS4 BLOC3S2, KIAA1667, LE ENSG00000100099 Hermansky-Pudlak syndrome 4 22 26443423-26483837 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB033106, HPA050189 Approved Approved Centrosome Expressed in all Expressed in all testis: 24.1 HPS5 BLOC2S2 ENSG00000110756 Hermansky-Pudlak syndrome 5 11 18278668-18322198 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all testis: 39.7 HPS6 BLOC2S3, FLJ22501 ENSG00000166189 Hermansky-Pudlak syndrome 6 10 102065390-102068038 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040687 Approved Expressed in all Expressed in all fallopian tube: 11.8 HRAS HRAS1 ENSG00000174775 Harvey rat sarcoma viral oncogene homolog 11 532242-537287 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002015, HPA049830 Approved Liver cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.0 HS1BP3 FLJ14249, HS1-BP3 ENSG00000118960 HCLS1 binding protein 3 2 20560448-20651089 Predicted intracellular proteins Evidence at protein level HPA035050 Approved Approved Nucleoli
Cytosol Liver cancer:2.97e-5 (unfavourable), Renal cancer:2.30e-4 (favourable) Expressed in all Expressed in all adrenal gland: 33.4 HS2ST1 KIAA0448 ENSG00000153936 Heparan sulfate 2-O-sulfotransferase 1 1 86914648-87109998 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043069, HPA043603, HPA075001 Supported Approved Mitochondria Liver cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 34.2 HS6ST1 HS6ST ENSG00000136720 Heparan sulfate 6-O-sulfotransferase 1 2 128236716-128318577 Disease related genes, Predicted secreted proteins Evidence at protein level HPA044586 Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 40.9 HSBP1 ENSG00000230989 Heat shock factor binding protein 1 16 83807843-83819737 Predicted intracellular proteins Evidence at protein level Ovarian cancer:2.96e-4 (favourable), Endometrial cancer:5.73e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 59.0 HSBP1L1 FLJ10967, MGC189743 ENSG00000226742 Heat shock factor binding protein 1-like 1 18 79964561-79970822 Predicted intracellular proteins Evidence at transcript level HPA048273 Approved Approved Nucleoplasm Expressed in all Expressed in all colon: 12.3 HSCB DNAJC20, HSC20, Jac1 ENSG00000100209 HscB mitochondrial iron-sulfur cluster co-chaperone 22 28742031-28757515 Predicted intracellular proteins Evidence at protein level HPA018447, HPA031518 Uncertain Supported Nucleus
Mitochondria
Cytosol Endometrial cancer:3.78e-4 (favourable), Urothelial cancer:8.38e-4 (favourable) Expressed in all Expressed in all adrenal gland: 13.3 HSD17B10 17b-HSD10, ABAD, CAMR, ERAB, HADH2, MHBD, MRPP2, MRXS10, SDR5C1 ENSG00000072506 Hydroxysteroid (17-beta) dehydrogenase 10 X 53431258-53434373 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001432 Approved Cervical cancer:2.80e-4 (favourable) Expressed in all Expressed in all liver: 126.2 HSD17B11 17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2 ENSG00000198189 Hydroxysteroid (17-beta) dehydrogenase 11 4 87336610-87391386 Enzymes, Predicted secreted proteins Evidence at protein level HPA021608 Approved Supported Lipid droplets Expressed in all Expressed in all small intestine: 301.2 HSD17B12 KAR, SDR12C1 ENSG00000149084 Hydroxysteroid (17-beta) dehydrogenase 12 11 43556436-43856617 Enzymes, Predicted membrane proteins Evidence at protein level HPA016427 Approved Renal cancer:2.10e-8 (favourable), Liver cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 205.0 HSD17B4 DBP, MFE-2, SDR8C1 ENSG00000133835 Hydroxysteroid (17-beta) dehydrogenase 4 5 119452443-119637199 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021302, HPA021311, HPA021479 Supported Validated Peroxisomes Renal cancer:6.31e-6 (favourable), Colorectal cancer:1.33e-4 (favourable) Expressed in all Expressed in all thyroid gland: 228.6 HSD3B7 C(27)-3BETA-HSD, SDR11E3 ENSG00000099377 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 16 30985207-30989152 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050521, HPA060847 Uncertain Supported Lipid droplets Renal cancer:1.60e-6 (unfavourable), Colorectal cancer:5.95e-4 (unfavourable) Expressed in all Expressed in all liver: 21.9 HSDL1 SDR12C3 ENSG00000103160 Hydroxysteroid dehydrogenase like 1 16 84122146-84145192 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045745 Supported Mitochondria Renal cancer:4.20e-7 (favourable), Liver cancer:3.50e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 45.6 HSDL2 C9orf99, SDR13C1 ENSG00000119471 Hydroxysteroid dehydrogenase like 2 9 112379937-112472410 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042890, HPA050453 Supported Supported Mitochondria Renal cancer:9.29e-7 (favourable), Endometrial cancer:9.23e-6 (favourable) Expressed in all Expressed in all adrenal gland: 79.7 HSF1 HSTF1 ENSG00000185122 Heat shock transcription factor 1 8 144291591-144314722 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004239, HPA008888 Supported Supported Nucleoplasm
Cytosol Liver cancer:4.95e-4 (unfavourable), Endometrial cancer:8.93e-4 (unfavourable) Expressed in all Expressed in all testis: 127.1 HSF2 ENSG00000025156 Heat shock transcription factor 2 6 122399546-122433119 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB016067, HPA031455 Approved Supported Nucleoplasm Liver cancer:1.51e-6 (unfavourable), Renal cancer:7.65e-4 (unfavourable) Expressed in all Expressed in all testis: 71.1 HSP90AA1 FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA ENSG00000080824 Heat shock protein 90kDa alpha (cytosolic), class A member 1 14 102080738-102139699 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002058 Approved Supported Cytosol Renal cancer:1.18e-5 (favourable), Liver cancer:3.09e-5 (unfavourable), Breast cancer:5.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1024.3 HSP90AB1 HSPC2, HSPCB ENSG00000096384 Heat shock protein 90kDa alpha (cytosolic), class B member 1 6 44246166-44253888 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005230, HPA055729 Approved Validated Cytosol Ovarian cancer:4.03e-4 (favourable), Renal cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all ovary: 1457.6 HSP90B1 GP96, GRP94, TRA1 ENSG00000166598 Heat shock protein 90kDa beta (Grp94), member 1 12 103930107-103953645 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003901, CAB005224, HPA008424 Supported Validated Endoplasmic reticulum Renal cancer:1.03e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 2376.1 HSPA13 STCH ENSG00000155304 Heat shock protein 70kDa family, member 13 21 14371115-14383484 Predicted secreted proteins Evidence at protein level HPA014797 Approved Expressed in all Expressed in all cerebral cortex: 55.9 HSPA14 HSP70-4, HSP70L1 ENSG00000187522 Heat shock 70kDa protein 14 10 14838164-14871741 Predicted intracellular proteins Evidence at protein level HPA046180 Approved Liver cancer:3.70e-8 (unfavourable), Renal cancer:1.09e-5 (unfavourable), Head and neck cancer:5.73e-4 (favourable), Ovarian cancer:9.16e-4 (favourable) Expressed in all Expressed in all testis: 65.2 HSPA4 HS24/P52, HSPH2 ENSG00000170606 Heat shock 70kDa protein 4 5 133051962-133106449 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA010023, CAB025529 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:4.13e-4 (unfavourable) Expressed in all Expressed in all testis: 116.4 HSPA5 BiP, GRP78 ENSG00000044574 Heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 9 125234853-125241330 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB005221, HPA038845, HPA038846 Supported Supported Cytosol Renal cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 965.5 HSPA8 HSC70, HSC71, HSP73, HSPA10 ENSG00000109971 Heat shock 70kDa protein 8 11 123057489-123063230 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002056, HPA052504 Uncertain Uncertain Nucleoplasm
Vesicles Colorectal cancer:6.14e-6 (favourable), Liver cancer:1.93e-4 (unfavourable), Renal cancer:3.81e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1122.1 HSPA9 GRP75, HSPA9B, mot-2, mthsp75, PBP74 ENSG00000113013 Heat shock 70kDa protein 9 (mortalin) 5 138554882-138575444 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000898, CAB005219 Supported Validated Mitochondria Breast cancer:2.93e-4 (unfavourable), Colorectal cancer:4.53e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 259.4 HSPB1 CMT2F, Hs.76067, Hsp25, HSP27, HSP28 ENSG00000106211 Heat shock 27kDa protein 1 7 76302544-76304295 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000497, CAB004439, CAB047330, CAB047331, CAB047332 Supported Validated Plasma membrane
Cytosol Colorectal cancer:9.94e-5 (unfavourable) Expressed in all Expressed in all esophagus: 1622.3 HSPB11 C1orf41, HSPCO34, IFT25, PP25 ENSG00000081870 Heat shock protein family B (small), member 11 1 53916574-53945929 Predicted intracellular proteins Evidence at protein level HPA030140 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:9.58e-7 (unfavourable), Renal cancer:1.03e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 116.2 HSPBP1 FES1, HspBP1 ENSG00000133265 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 19 55262231-55280381 Predicted intracellular proteins Evidence at protein level CAB005865, HPA071444 Supported Approved Vesicles
Cytosol Expressed in all Expressed in all fallopian tube: 39.6 HSPD1 GroEL, HSP60, SPG13 ENSG00000144381 Heat shock 60kDa protein 1 (chaperonin) 2 197486581-197516737 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001523, CAB002775, HPA050025, CAB072816 Supported Validated Mitochondria Endometrial cancer:1.61e-4 (unfavourable), Liver cancer:2.25e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 838.0 HSPE1 CPN10, EPF, GroES, HSP10 ENSG00000115541 Heat shock 10kDa protein 1 2 197499994-197503457 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017366, HPA038755, HPA048272 Supported Expressed in all Expressed in all adrenal gland: 653.6 HSPG2 perlecan, PRCAN, SJS1 ENSG00000142798 Heparan sulfate proteoglycan 2 1 21822245-21937297 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB009820, HPA018892, CAB020718 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:2.82e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 135.3 HSPH1 HSP105A, HSP105B, KIAA0201, NY-CO-25 ENSG00000120694 Heat shock 105kDa/110kDa protein 1 13 31134974-31162388 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB002060, HPA028675, HPA031569 Supported Validated Nucleoplasm
Cytosol Liver cancer:1.41e-5 (unfavourable), Head and neck cancer:4.90e-4 (unfavourable) Expressed in all Expressed in all testis: 123.1 HTATIP2 CC3, FLJ26963, SDR44U1, TIP30 ENSG00000109854 HIV-1 Tat interactive protein 2, 30kDa 11 20363685-20383783 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA006417, HPA024321 Approved Supported Cytosol Liver cancer:2.86e-4 (unfavourable), Pancreatic cancer:6.18e-4 (unfavourable), Renal cancer:8.01e-4 (unfavourable) Expressed in all Expressed in all duodenum: 139.0 HTATSF1 TAT-SF1 ENSG00000102241 HIV-1 Tat specific factor 1 X 136497079-136512346 Predicted intracellular proteins Evidence at protein level HPA000504 Supported Validated Nucleoplasm Renal cancer:8.13e-8 (favourable), Cervical cancer:3.78e-4 (favourable) Expressed in all Expressed in all adrenal gland: 126.3 HTT HD, IT15 ENSG00000197386 Huntingtin 4 3074681-3243959 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002756, HPA026114 Supported Supported Nucleoplasm
Cytosol Renal cancer:2.41e-12 (favourable), Head and neck cancer:3.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.8 HUWE1 Ib772, KIAA0312, UREB1 ENSG00000086758 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase X 53532096-53686729 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002548, CAB022718 Approved Validated Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 94.8 HYAL2 LuCa-2, LUCA2 ENSG00000068001 Hyaluronoglucosaminidase 2 3 50317790-50322906 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036436, HPA077941 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all spleen: 217.8 HYI HT036 ENSG00000178922 Hydroxypyruvate isomerase (putative) 1 43451003-43453989 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040092 Uncertain Approved Golgi apparatus
Plasma membrane
Cytosol Urothelial cancer:2.72e-5 (favourable), Renal cancer:2.75e-5 (unfavourable), Colorectal cancer:4.96e-4 (unfavourable), Liver cancer:5.55e-4 (unfavourable), Breast cancer:9.18e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 80.3 HYOU1 Grp170, HSP12A, ORP150 ENSG00000149428 Hypoxia up-regulated 1 11 119044189-119057202 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA049296 Approved Renal cancer:5.10e-5 (unfavourable), Endometrial cancer:2.58e-4 (favourable), Thyroid cancer:5.00e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 111.5 IAH1 ENSG00000134330 Isoamyl acetate-hydrolyzing esterase 1 homolog 2 9473658-9496543 Predicted intracellular proteins Evidence at protein level HPA040523 Supported Nucleoplasm Renal cancer:3.64e-4 (unfavourable) Expressed in all Expressed in all testis: 121.1 IARS IARS1, ILRS ENSG00000196305 Isoleucyl-tRNA synthetase 9 92210207-92293756 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029806 Approved Supported Cytosol Liver cancer:4.98e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 139.0 IARS2 FLJ10326 ENSG00000067704 Isoleucyl-tRNA synthetase 2, mitochondrial 1 220094102-220148041 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA024212, HPA024594, HPA024596 Supported Validated Mitochondria Pancreatic cancer:9.24e-5 (unfavourable), Cervical cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 141.6 IBTK BTBD26, BTKI, DKFZP564B116 ENSG00000005700 Inhibitor of Bruton agammaglobulinemia tyrosine kinase 6 82169983-82247754 Predicted intracellular proteins Evidence at protein level HPA023826, HPA048438 Uncertain Supported Nucleoplasm Cervical cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.0 ICAM1 BB2, CD54 ENSG00000090339 Intercellular adhesion molecule 1 19 10270835-10286615 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA002126, CAB002142, HPA004877 Supported Uncertain Plasma membrane
Cytosol Renal cancer:1.32e-6 (unfavourable), Breast cancer:7.09e-4 (favourable) Expressed in all Expressed in all lung: 256.0 ICAM2 CD102 ENSG00000108622 Intercellular adhesion molecule 2 17 64002594-64020634 CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA071155 Uncertain Cytosol Expressed in all Expressed in all spleen: 203.8 ICAM3 CD50, CDW50, ICAM-R ENSG00000076662 Intercellular adhesion molecule 3 19 10333776-10339823 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002498, HPA049820 Supported Approved Nucleus
Nuclear membrane
Mitochondria Mixed Expressed in all bone marrow: 112.2 ICE1 KIAA0947 ENSG00000164151 Interactor of little elongation complex ELL subunit 1 5 5420664-5490234 Predicted intracellular proteins Evidence at protein level HPA054452, HPA061934 Uncertain Supported Nucleoplasm
Nuclear bodies Liver cancer:1.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 27.7 ICE2 BRCC1, FLJ11896, NARG2 ENSG00000128915 Interactor of little elongation complex ELL subunit 2 15 60419609-60479160 Predicted intracellular proteins Evidence at protein level HPA040058 Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 52.9 ICMT HSTE14, PCCMT, PPMT ENSG00000116237 Isoprenylcysteine carboxyl methyltransferase 1 6221193-6235972 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA032024, HPA032025 Uncertain Liver cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 45.0 ICT1 DS-1 ENSG00000167862 Immature colon carcinoma transcript 1 17 75012670-75021261 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003634 Approved Supported Nucleoplasm
Mitochondria Renal cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all kidney: 35.8 ID1 bHLHb24, dJ857M17.1.2 ENSG00000125968 Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 20 31605283-31606515 Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB025915, HPA051456, HPA058518 Approved Validated Nucleoplasm
Golgi apparatus Lung cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 211.5 IDE ENSG00000119912 Insulin-degrading enzyme 10 92451684-92574076 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA063478 Approved Endometrial cancer:3.53e-4 (favourable), Colorectal cancer:3.69e-4 (favourable) Expressed in all Expressed in all skin: 63.5 IDH1 ENSG00000138413 Isocitrate dehydrogenase 1 (NADP+), soluble 2 208236227-208266074 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033218, HPA035248, HPA057936, CAB062556 Supported Approved Nuclear bodies
Cytosol Renal cancer:2.45e-5 (unfavourable), Liver cancer:6.93e-5 (unfavourable) Expressed in all Expressed in all prostate: 359.5 IDH2 ENSG00000182054 Isocitrate dehydrogenase 2 (NADP+), mitochondrial 15 90083045-90102504 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007831 Supported Supported Mitochondria Cervical cancer:5.15e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 450.2 IDH3A ENSG00000166411 Isocitrate dehydrogenase 3 (NAD+) alpha 15 78131498-78171949 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041465, HPA062971 Supported Validated Mitochondria Renal cancer:6.49e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 44.3 IDH3B RP46 ENSG00000101365 Isocitrate dehydrogenase 3 (NAD+) beta 20 2658395-2664219 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA049387, HPA054180 Supported Validated Mitochondria Renal cancer:6.78e-8 (favourable), Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 98.7 IDH3G ENSG00000067829 Isocitrate dehydrogenase 3 (NAD+) gamma X 153785766-153794523 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000425, HPA002017 Supported Validated Mitochondria Renal cancer:5.73e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 65.1 IDI1 ENSG00000067064 Isopentenyl-diphosphate delta isomerase 1 10 1039908-1049170 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039169 Approved Renal cancer:1.46e-4 (favourable) Expressed in all Expressed in all breast: 241.1 IDS SIDS ENSG00000010404 Iduronate 2-sulfatase X 149476990-149521096 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 437.1 IDUA MPS1 ENSG00000127415 Iduronidase, alpha-L- 4 986997-1004506 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025901, HPA046979, HPA054254 Supported Renal cancer:7.87e-5 (unfavourable), Urothelial cancer:8.04e-5 (favourable), Colorectal cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 16.9 IER2 ETR101 ENSG00000160888 Immediate early response 2 19 13150415-13154908 Predicted intracellular proteins Evidence at protein level HPA055387, HPA060574 Validated Nucleoplasm Expressed in all Expressed in all fallopian tube: 159.7 IER3IP1 ENSG00000134049 Immediate early response 3 interacting protein 1 18 47152998-47176374 Disease related genes, Predicted membrane proteins Evidence at protein level HPA010027 Supported Supported Endoplasmic reticulum Liver cancer:6.47e-6 (unfavourable), Ovarian cancer:8.59e-4 (favourable) Expressed in all Expressed in all kidney: 33.8 IFFO2 ENSG00000169991 Intermediate filament family orphan 2 1 18904281-18956686 Predicted intracellular proteins Evidence at protein level HPA015987, HPA064603 Approved Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all skin: 72.6 IFI16 IFNGIP1, PYHIN2 ENSG00000163565 Interferon, gamma-inducible protein 16 1 158999968-159055155 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002134, CAB016293 Supported Supported Nucleus
Nucleoli
Cytosol Renal cancer:1.11e-16 (unfavourable) Expressed in all Expressed in all lymph node: 165.5 IFI27 FAM14D, ISG12, P27 ENSG00000165949 Interferon, alpha-inducible protein 27 14 94104836-94116698 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA028875 Uncertain Ovarian cancer:8.80e-4 (favourable) Expressed in all Expressed in all spleen: 743.8 IFI27L2 FAM14A, TLH29 ENSG00000119632 Interferon, alpha-inducible protein 27-like 2 14 94127779-94130253 Predicted secreted proteins Evidence at protein level HPA049588 Approved Nucleoli
Cytosol Expressed in all Expressed in all adrenal gland: 47.7 IFI30 GILT, IFI-30, IP-30, IP30, MGC32056 ENSG00000216490 Interferon, gamma-inducible protein 30 19 18173162-18178117 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026650 Approved Supported Vesicles
Cytosol Mixed Expressed in all appendix: 848.1 IFI35 IFP35 ENSG00000068079 Interferon-induced protein 35 17 43006725-43014456 Predicted intracellular proteins Evidence at protein level HPA045946 Approved Nucleoplasm
Cytosol Renal cancer:4.03e-5 (unfavourable), Breast cancer:1.41e-4 (favourable) Expressed in all Expressed in all spleen: 44.8 IFI44 MTAP44, p44, TLDC5 ENSG00000137965 Interferon-induced protein 44 1 78649796-78664078 Predicted intracellular proteins Evidence at protein level HPA027148, HPA043858 Approved Approved Nucleoplasm Renal cancer:1.37e-8 (unfavourable) Expressed in all Expressed in all spleen: 90.2 IFI6 6-16, FAM14C, G1P3, IFI-6-16, IFI616 ENSG00000126709 Interferon, alpha-inducible protein 6 1 27666061-27672218 Predicted membrane proteins Evidence at transcript level HPA005543 Approved Approved Mitochondria Expressed in all Expressed in all placenta: 412.1 IFIT1 G10P1, GARG-16, IFI56, IFNAI1 ENSG00000185745 Interferon-induced protein with tetratricopeptide repeats 1 10 89392546-89406486 Predicted intracellular proteins Evidence at protein level CAB045980, HPA055380 Approved Supported Cytosol Expressed in all Expressed in all spleen: 61.6 IFIT3 CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, RIG-G ENSG00000119917 Interferon-induced protein with tetratricopeptide repeats 3 10 89327894-89340971 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059914 Approved Supported Mitochondria
Cytosol Renal cancer:3.17e-4 (unfavourable) Expressed in all Expressed in all lung: 63.4 IFITM1 9-27, CD225, IFI17 ENSG00000185885 Interferon induced transmembrane protein 1 11 313506-315272 CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA004810, CAB017615 Supported Supported Cytosol Renal cancer:5.77e-9 (unfavourable) Expressed in all Expressed in all epididymis: 904.7 IFITM2 1-8D ENSG00000185201 Interferon induced transmembrane protein 2 11 307631-315272 Predicted membrane proteins, Transporters Evidence at protein level HPA004337 Uncertain Renal cancer:2.37e-9 (unfavourable) Expressed in all Expressed in all appendix: 722.4 IFITM3 1-8U ENSG00000142089 Interferon induced transmembrane protein 3 11 319669-327537 Predicted membrane proteins, Transporters Evidence at protein level HPA004337 Uncertain Renal cancer:5.78e-7 (unfavourable) Expressed in all Expressed in all fallopian tube: 1027.4 IFNAR1 IFNAR, IFRC ENSG00000142166 Interferon (alpha, beta and omega) receptor 1 21 33324477-33359862 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018015, HPA029226 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 60.2 IFNAR2 IFNABR ENSG00000159110 Interferon (alpha, beta and omega) receptor 2 21 33229901-33265675 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB025889 Approved Renal cancer:7.54e-7 (unfavourable) Expressed in all Expressed in all spleen: 59.7 IFNGR1 CD119, IFNGR ENSG00000027697 Interferon gamma receptor 1 6 137197484-137219449 CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029213, HPA063871 Approved Supported Endoplasmic reticulum
Vesicles
Plasma membrane Renal cancer:5.48e-4 (unfavourable) Expressed in all Expressed in all spleen: 225.2 IFRD1 PC4, TIS7 ENSG00000006652 Interferon-related developmental regulator 1 7 112422968-112481017 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024122 Approved Approved Plasma membrane
Cytosol Ovarian cancer:5.45e-4 (favourable) Expressed in all Expressed in all bone marrow: 130.1 IFRD2 IFNRP, SKMc15, SM15 ENSG00000214706 Interferon-related developmental regulator 2 3 50287732-50292918 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA068560 Approved Nucleoplasm Renal cancer:2.50e-4 (favourable), Breast cancer:7.22e-4 (favourable) Expressed in all Expressed in all thyroid gland: 28.6 IFT122 SPG, WDR10, WDR10p, WDR140 ENSG00000163913 Intraflagellar transport 122 3 129440036-129520507 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041815 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 147.3 IFT172 NPHP17, osm-1, SLB, wim ENSG00000138002 Intraflagellar transport 172 2 27444371-27489789 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044893 Uncertain Approved Vesicles Liver cancer:6.05e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.2 IFT20 ENSG00000109083 Intraflagellar transport 20 17 28328325-28335489 Predicted intracellular proteins Evidence at protein level HPA021376 Approved Approved Microtubules Renal cancer:5.09e-7 (unfavourable), Liver cancer:1.96e-4 (unfavourable), Endometrial cancer:8.65e-4 (unfavourable) Expressed in all Expressed in all testis: 78.3 IFT22 DKFZp761N0823, FLJ13225, FLJ14117, RABL5 ENSG00000128581 Intraflagellar transport 22 7 101313367-101321823 Predicted intracellular proteins Evidence at protein level HPA042930 Approved Approved Microtubules
Cytosol Expressed in all Expressed in all testis: 138.8 IFT27 BBS19, RABL4, RAYL ENSG00000100360 Intraflagellar transport 27 22 36758202-36776256 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA018418 Uncertain Approved Nucleoplasm
Mitochondria Endometrial cancer:1.91e-4 (favourable), Urothelial cancer:5.55e-4 (favourable) Expressed in all Expressed in all fallopian tube: 56.6 IFT43 C14orf179, FLJ32173, MGC16028 ENSG00000119650 Intraflagellar transport 43 14 75902136-76084585 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003438 Approved Supported Microtubules
Microtubule organizing center Expressed in all Expressed in all fallopian tube: 97.9 IFT46 C11orf2, C11orf60, CFAP32, FLJ21827 ENSG00000118096 Intraflagellar transport 46 11 118544528-118572970 Predicted intracellular proteins Evidence at protein level HPA037909, HPA057550 Approved Approved Actin filaments Expressed in all Expressed in all fallopian tube: 96.4 IFT52 C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5 ENSG00000101052 Intraflagellar transport 52 20 43590931-43647296 Predicted intracellular proteins Evidence at protein level HPA063367, HPA067423 Supported Approved Cytosol Liver cancer:3.30e-6 (unfavourable), Testis cancer:3.33e-4 (favourable) Expressed in all Expressed in all fallopian tube: 60.6 IFT74 CCDC2, CMG-1, CMG1, FLJ22621 ENSG00000096872 Intraflagellar transport 74 9 26947039-27062930 Predicted intracellular proteins Evidence at protein level HPA020247, HPA026684 Approved Approved Golgi apparatus Expressed in all Expressed in all testis: 83.7 IFT80 KIAA1374, WDR56 ENSG00000068885 Intraflagellar transport 80 3 160256986-160399880 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035868 Uncertain Expressed in all Expressed in all testis: 45.6 IFT88 D13S1056E, hTg737, MGC26259, Tg737, TTC10 ENSG00000032742 Intraflagellar transport 88 13 20567069-20691437 Predicted intracellular proteins Evidence at protein level Renal cancer:1.33e-4 (favourable), Pancreatic cancer:5.17e-4 (favourable) Expressed in all Expressed in all testis: 125.9 IGBP1 IBP1 ENSG00000089289 Immunoglobulin (CD79A) binding protein 1 X 70133449-70166324 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000634, HPA001004, CAB034139 Approved Approved Microtubules
Cytosol Expressed in all Expressed in all ovary: 146.8 IGF2R CD222, CIMPR, M6P-R, MPR1, MPRI ENSG00000197081 Insulin-like growth factor 2 receptor 6 159969099-160113507 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009661, HPA011332 Supported Validated Golgi apparatus
Vesicles Cervical cancer:2.92e-5 (unfavourable), Breast cancer:3.01e-4 (unfavourable), Urothelial cancer:6.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.5 IGFBP2 IBP2 ENSG00000115457 Insulin-like growth factor binding protein 2, 36kDa 2 216632828-216664436 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA077723 Approved Endoplasmic reticulum Renal cancer:2.22e-5 (unfavourable), Melanoma:2.43e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 276.7 IGFBP4 BP-4, HT29-IGFBP, IBP4, IGFBP-4 ENSG00000141753 Insulin-like growth factor binding protein 4 17 40443461-40457731 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA066240 Supported Renal cancer:2.72e-5 (unfavourable), Endometrial cancer:3.54e-4 (favourable), Liver cancer:5.49e-4 (favourable) Expressed in all Expressed in all smooth muscle: 923.3 IGFBP7 FSTL2, IGFBP-7, MAC25, PSF ENSG00000163453 Insulin-like growth factor binding protein 7 4 57030773-57110385 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002196, CAB020668 Approved Uncertain Golgi apparatus Expressed in all Expressed in all seminal vesicle: 910.8 IGHMBP2 CATF1, CMT2S, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7 ENSG00000132740 Immunoglobulin mu binding protein 2 11 68903842-68940602 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA060994 Approved Nucleus Renal cancer:1.29e-8 (unfavourable), Pancreatic cancer:5.89e-4 (favourable) Expressed in all Expressed in all testis: 28.0 IGSF8 CD316, CD81P3, EWI2, PGRL ENSG00000162729 Immunoglobulin superfamily, member 8 1 160091340-160098943 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011917 Uncertain Cervical cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 108.1 IK ENSG00000113141 IK cytokine, down-regulator of HLA II 5 140647058-140662479 Predicted intracellular proteins Evidence at protein level HPA048798 Supported Validated Nuclear speckles Liver cancer:2.32e-7 (unfavourable), Cervical cancer:1.29e-4 (favourable) Expressed in all Expressed in all fallopian tube: 228.5 IKBKAP DYS, ELP1, IKAP, IKI3, TOT1 ENSG00000070061 Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 9 108867517-108934116 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB021340, HPA049677, HPA050686 Approved Supported Nucleoplasm
Cytosol Breast cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.9 IKBKG FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9 ENSG00000269335 Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma X 154541199-154565046 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA000426, CAB010373 Uncertain Validated Cytosol Expressed in all Expressed in all spleen: 37.9 IKZF5 FLJ22973, Pegasus, ZNFN1A5 ENSG00000095574 IKAROS family zinc finger 5 (Pegasus) 10 122990806-123008817 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015297, HPA051574 Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all bone marrow: 21.4 IL10RB CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 ENSG00000243646 Interleukin 10 receptor, beta 21 33266358-33297234 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB020670, HPA047550 Approved Approved Cytosol Renal cancer:5.62e-9 (unfavourable) Expressed in all Expressed in all placenta: 89.0 IL11RA ENSG00000137070 Interleukin 11 receptor, alpha 9 34650702-34661892 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013162, CAB032830, HPA036652 Supported Renal cancer:6.56e-4 (unfavourable) Expressed in all Expressed in all skin: 72.6 IL13RA1 CD213a1, IL-13Ra, NR4 ENSG00000131724 Interleukin 13 receptor, alpha 1 X 118727572-118794539 CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA000293, HPA001795 Approved Nucleoplasm
Golgi apparatus Renal cancer:1.19e-8 (unfavourable) Expressed in all Expressed in all lung: 72.1 IL15RA CD215, IL-15RA ENSG00000134470 Interleukin 15 receptor, alpha 10 5937569-5978187 CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026215 Approved Uncertain Plasma membrane
Cytosol Renal cancer:1.27e-12 (unfavourable), Liver cancer:2.67e-6 (unfavourable), Pancreatic cancer:5.35e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 33.5 IL17RC IL17-RL ENSG00000163702 Interleukin 17 receptor C 3 9917074-9933630 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA019885, CAB026255, HPA048514 Approved Uncertain Microtubules
Centrosome Endometrial cancer:1.38e-4 (favourable) Expressed in all Expressed in all prostate: 21.3 IL1R1 CD121A, D2S1473, IL1R, IL1RA ENSG00000115594 Interleukin 1 receptor, type I 2 102064544-102179874 Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA001237, HPA005823, CAB007779, HPA029560 Approved Validated Vesicles Renal cancer:6.92e-6 (unfavourable) Expressed in all Expressed in all cervix, uterine: 244.6 IL32 NK4, TAIF, TAIFb, TAIFd ENSG00000008517 Interleukin 32 16 3065297-3082192 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029397, CAB030029 Approved Endometrial cancer:1.33e-4 (favourable) Expressed in all Expressed in all small intestine: 632.5 IL3RA CD123 ENSG00000185291 Interleukin 3 receptor, alpha (low affinity) X 1336616-1382689 CD markers, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003539, CAB018374 Approved Cervical cancer:4.27e-4 (favourable), Breast cancer:9.78e-4 (favourable) Expressed in all Expressed in all lung: 33.8 IL4R CD124 ENSG00000077238 Interleukin 4 receptor 16 27313668-27364778 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004451, HPA050124 Supported Approved Cytosol Renal cancer:1.23e-5 (unfavourable), Endometrial cancer:6.43e-4 (favourable) Expressed in all Expressed in all lymph node: 139.5 IL6R CD126 ENSG00000160712 Interleukin 6 receptor 1 154405193-154469450 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:1.65e-4 (favourable) Expressed in all Expressed in all appendix: 34.4 IL6ST CD130, GP130 ENSG00000134352 Interleukin 6 signal transducer 5 55935095-55994993 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010558, CAB025784 Uncertain Supported Golgi apparatus
Plasma membrane Renal cancer:5.05e-4 (unfavourable) Expressed in all Expressed in all placenta: 327.1 IL7R CD127 ENSG00000168685 Interleukin 7 receptor 5 35852695-35879603 Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB010215 Approved Supported Plasma membrane Expressed in all Expressed in all appendix: 188.9 ILF2 NF45 ENSG00000143621 Interleukin enhancer binding factor 2 1 153661788-153671048 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007484 Supported Validated Nucleus
Nucleoli Liver cancer:5.71e-8 (unfavourable), Renal cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all testis: 210.7 ILF3 DRBP76, MPHOSPH4, MPP4, NF90, NFAR-1 ENSG00000129351 Interleukin enhancer binding factor 3, 90kDa 19 10654261-10692417 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001897 Supported Supported Nucleoplasm
Nucleoli
Mitochondria Melanoma:1.57e-4 (unfavourable), Renal cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all testis: 149.2 ILK ENSG00000166333 Integrin-linked kinase 11 6603708-6610874 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004041, HPA048437 Supported Validated Cell Junctions
Focal adhesion sites Renal cancer:2.44e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 554.5 ILKAP DKFZP434J2031, FLJ10181 ENSG00000132323 Integrin-linked kinase-associated serine/threonine phosphatase 2 238170401-238203729 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004752, HPA056099 Uncertain Approved Nucleoplasm Renal cancer:9.89e-6 (unfavourable), Liver cancer:1.04e-4 (unfavourable) Expressed in all Expressed in all testis: 28.0 ILVBL 209L8, AHAS, FLJ39061, ILV2H, MGC1269, MGC19535 ENSG00000105135 IlvB (bacterial acetolactate synthase)-like 19 15114984-15125785 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA067682 Approved Approved Golgi apparatus
Vesicles Renal cancer:1.91e-8 (favourable), Endometrial cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 80.0 IMMP1L FLJ25059, IMMP1 ENSG00000148950 Inner mitochondrial membrane peptidase subunit 1 11 31432401-31509645 Enzymes, Predicted intracellular proteins Evidence at protein level Pancreatic cancer:6.72e-4 (favourable), Liver cancer:7.97e-4 (unfavourable) Expressed in all Expressed in all epididymis: 44.8 IMMP2L IMMP2L-IT1, IMP2 ENSG00000184903 Inner mitochondrial membrane peptidase subunit 2 7 110663051-111562517 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026711 Approved Approved Mitochondria Head and neck cancer:1.89e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.4 IMMT HMP, Mic60, MINOS2, P87, P89 ENSG00000132305 Inner membrane protein, mitochondrial 2 86143932-86195770 Predicted intracellular proteins Evidence at protein level CAB022439, HPA036164, HPA036165 Supported Validated Mitochondria Renal cancer:3.51e-6 (favourable), Endometrial cancer:1.06e-4 (unfavourable), Liver cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 106.1 IMP3 BRMS2, C15orf12, FLJ10968, MRPS4 ENSG00000177971 IMP3, U3 small nucleolar ribonucleoprotein 15 75639085-75648706 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA060955, HPA061177 Validated Nucleus
Nucleoli Expressed in all Expressed in all spleen: 48.4 IMPA1 IMPA ENSG00000133731 Inositol(myo)-1(or 4)-monophosphatase 1 8 81657961-81686693 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037489 Approved Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 71.8 IMPA2 ENSG00000141401 Inositol(myo)-1(or 4)-monophosphatase 2 18 11981025-12030883 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029561 Approved Approved Nucleoplasm
Mitochondria Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all skin: 129.8 IMPACT RWDD5 ENSG00000154059 Impact RWD domain protein 18 24426616-24453535 Predicted intracellular proteins Evidence at protein level HPA041045, HPA041968 Approved Approved Nucleoplasm Renal cancer:7.90e-4 (favourable) Expressed in all Expressed in all testis: 64.9 IMPAD1 FLJ20421, gPAPP, IMPA3 ENSG00000104331 Inositol monophosphatase domain containing 1 8 56957933-56993844 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009411 Supported Supported Nucleus
Golgi apparatus
Cytosol Expressed in all Expressed in all parathyroid gland: 51.8 IMPDH1 LCA11, RP10, sWSS2608 ENSG00000106348 IMP (inosine 5'-monophosphate) dehydrogenase 1 7 128392277-128410252 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA001400 Approved Supported Cytosol
Rods & Rings Renal cancer:1.78e-12 (unfavourable), Liver cancer:1.12e-7 (unfavourable), Urothelial cancer:3.72e-5 (unfavourable), Glioma:1.17e-4 (unfavourable), Cervical cancer:3.87e-4 (unfavourable) Expressed in all Expressed in all appendix: 47.2 IMPDH2 ENSG00000178035 IMP (inosine 5'-monophosphate) dehydrogenase 2 3 49024325-49029408 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001400, CAB020717 Approved Validated Cytosol
Rods & Rings Liver cancer:3.22e-4 (unfavourable) Expressed in all Expressed in all ovary: 421.1 INADL Cipp, PATJ ENSG00000132849 InaD-like (Drosophila) 1 61742477-62178675 Predicted intracellular proteins Evidence at protein level HPA066352, HPA066960, HPA069079 Approved Supported Cell Junctions
Microtubule organizing center
Cytosol Renal cancer:1.47e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 35.2 INAFM1 PRR24 ENSG00000257704 InaF-motif containing 1 19 47274453-47275707 Predicted intracellular proteins Evidence at transcript level HPA064015 Uncertain Colorectal cancer:3.20e-5 (unfavourable), Renal cancer:3.04e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 23.4 INF2 C14orf151, C14orf173, MGC13251 ENSG00000203485 Inverted formin, FH2 and WH2 domain containing 14 104689606-104722535 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000724 Approved Approved Nuclear bodies
Endoplasmic reticulum Liver cancer:8.18e-4 (unfavourable) Expressed in all Expressed in all stomach: 56.6 ING1 p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a ENSG00000153487 Inhibitor of growth family, member 1 13 110712736-110723339 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB016136, CAB017773, HPA052591 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:5.81e-4 (favourable) Expressed in all Expressed in all ovary: 20.9 ING2 ING1L, p33ING2 ENSG00000168556 Inhibitor of growth family, member 2 4 183504994-183511096 Predicted intracellular proteins Evidence at protein level HPA019486, HPA021517 Supported Supported Nucleoplasm
Golgi apparatus
Cytosol Breast cancer:5.43e-4 (favourable), Liver cancer:8.87e-4 (unfavourable) Expressed in all Expressed in all ovary: 63.1 ING3 Eaf4, FLJ20089, MEAF4, p47ING3 ENSG00000071243 Inhibitor of growth family, member 3 7 120950749-120977216 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA067388, HPA067575 Approved Supported Nucleus Expressed in all Expressed in all bone marrow: 50.4 ING4 my036, p29ING4 ENSG00000111653 Inhibitor of growth family, member 4 12 6650280-6663148 Predicted intracellular proteins Evidence at protein level HPA031817, HPA057338 Approved Supported Nucleoplasm Lung cancer:5.16e-4 (favourable) Expressed in all Expressed in all fallopian tube,thyroid gland: 43.2 ING5 FLJ23842, p28ING5 ENSG00000168395 Inhibitor of growth family, member 5 2 241702035-241729478 Predicted intracellular proteins Evidence at protein level HPA042685 Approved Liver cancer:2.86e-5 (unfavourable), Pancreatic cancer:1.60e-4 (favourable) Expressed in all Expressed in all thyroid gland: 22.0 INO80 hINO80, Ino80, INO80A, INOC1, KIAA1259 ENSG00000128908 INO80 complex subunit 15 40978880-41116354 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041417, HPA041484 Validated Nucleoplasm
Nuclear bodies Renal cancer:6.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.9 INO80B hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4 ENSG00000115274 INO80 complex subunit B 2 74455023-74457960 Predicted intracellular proteins Evidence at protein level HPA042717 Supported Nucleus
Plasma membrane
Cytosol Renal cancer:1.56e-5 (unfavourable), Breast cancer:2.89e-4 (favourable), Stomach cancer:8.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 42.0 INO80C C18orf37, FLJ38183, hIes6, IES6 ENSG00000153391 INO80 complex subunit C 18 35452230-35497991 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049060 Approved Supported Nucleoli fibrillar center Endometrial cancer:2.62e-5 (unfavourable), Cervical cancer:3.58e-4 (favourable) Expressed in all Expressed in all testis: 165.6 INO80D FLJ20309 ENSG00000114933 INO80 complex subunit D 2 205993721-206086303 Predicted intracellular proteins Evidence at protein level HPA043976 Approved Head and neck cancer:5.53e-4 (favourable) Expressed in all Expressed in all testis: 30.1 INO80E CCDC95, FLJ90652 ENSG00000169592 INO80 complex subunit E 16 29995294-30005793 Predicted intracellular proteins Evidence at protein level HPA043146 Approved Supported Nucleoplasm
Nucleoli Expressed in all Expressed in all fallopian tube: 62.8 INPP1 ENSG00000151689 Inositol polyphosphate-1-phosphatase 2 190343470-190371665 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036698, HPA036699 Supported Uncertain Vesicles
Microtubule organizing center Thyroid cancer:1.12e-5 (favourable), Urothelial cancer:5.70e-4 (favourable) Expressed in all Expressed in all testis: 73.2 INPP4A INPP4 ENSG00000040933 Inositol polyphosphate-4-phosphatase type I A 2 98444854-98594390 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001628 Approved Approved Nucleus
Nuclear membrane Endometrial cancer:3.70e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 38.8 INPP5A 5PTASE ENSG00000068383 Inositol polyphosphate-5-phosphatase A 10 132537820-132783480 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012285, HPA066549 Supported Approved Cytosol Renal cancer:3.15e-4 (favourable), Breast cancer:7.47e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 60.5 INPP5B ENSG00000204084 Inositol polyphosphate-5-phosphatase B 1 37860697-37947057 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028803 Approved Approved Cytosol Renal cancer:6.11e-5 (unfavourable), Head and neck cancer:1.11e-4 (favourable), Pancreatic cancer:5.33e-4 (favourable) Expressed in all Expressed in all ovary: 26.2 INPP5E CORS1, JBTS1, PPI5PIV ENSG00000148384 Inositol polyphosphate-5-phosphatase E 9 136428619-136439822 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA065758 Approved Pancreatic cancer:1.82e-4 (favourable) Expressed in all Expressed in all testis: 16.0 INPP5F hSac2, KIAA0966, SAC2 ENSG00000198825 Inositol polyphosphate-5-phosphatase F 10 119726097-119829278 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all cerebral cortex: 112.6 INPP5K SKIP ENSG00000132376 Inositol polyphosphate-5-phosphatase K 17 1494571-1516888 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031044 Uncertain Pancreatic cancer:1.47e-6 (favourable), Endometrial cancer:2.33e-5 (favourable), Cervical cancer:3.91e-4 (favourable) Expressed in all Expressed in all adipose tissue: 32.1 INPPL1 SHIP2 ENSG00000165458 Inositol polyphosphate phosphatase-like 1 11 72223701-72239105 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037601 Approved Supported Golgi apparatus
Cytosol Liver cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all spleen: 65.5 INSIG1 CL-6, MGC1405 ENSG00000186480 Insulin induced gene 1 7 155297776-155310235 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA071524 Approved Vesicles Thyroid cancer:9.62e-4 (unfavourable) Expressed in all Expressed in all liver: 281.1 INSIG2 ENSG00000125629 Insulin induced gene 2 2 118088452-118110997 Predicted membrane proteins Evidence at protein level CAB033861 Uncertain Pancreatic cancer:2.19e-6 (unfavourable), Renal cancer:4.11e-6 (unfavourable), Head and neck cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 27.9 INSR CD220 ENSG00000171105 Insulin receptor 19 7112255-7294034 CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA036302, HPA036303 Uncertain Supported Vesicles Expressed in all Expressed in all ovary,spleen: 35.4 INTS1 DKFZp586J0619, INT1, KIAA1440, NET28 ENSG00000164880 Integrator complex subunit 1 7 1470277-1504367 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021658, HPA053009 Approved Approved Nucleoplasm Liver cancer:1.66e-4 (unfavourable), Pancreatic cancer:4.83e-4 (favourable) Expressed in all Expressed in all testis: 41.9 INTS10 C8orf35, FLJ10569, INT10 ENSG00000104613 Integrator complex subunit 10 8 19817140-19852083 Predicted intracellular proteins Evidence at protein level HPA039129, HPA050570 Uncertain Approved Nucleoplasm
Cytosol Endometrial cancer:1.22e-4 (favourable), Colorectal cancer:4.00e-4 (favourable) Expressed in all Expressed in all thyroid gland: 64.7 INTS12 INT12, PHF22, SBBI22 ENSG00000138785 Integrator complex subunit 12 4 105682627-105895986 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA035772, HPA041814 Approved Approved Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Liver cancer:2.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 33.5 INTS3 C1orf60, FLJ21919, INT3, SOSS-A ENSG00000143624 Integrator complex subunit 3 1 153728067-153774808 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA074391 Supported Nucleus
Nucleoli Renal cancer:1.34e-6 (unfavourable), Pancreatic cancer:5.42e-4 (favourable) Expressed in all Expressed in all fallopian tube: 16.4 INTS4 INT4, MGC16733, MST093 ENSG00000149262 Integrator complex subunit 4 11 77878720-77994678 Predicted intracellular proteins Evidence at protein level HPA042378 Uncertain Approved Nucleoli Liver cancer:9.44e-6 (unfavourable), Thyroid cancer:9.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.6 INTS5 INT5, KIAA1698 ENSG00000185085 Integrator complex subunit 5 11 62646848-62653302 Predicted membrane proteins Evidence at protein level HPA056915 Uncertain Supported Nucleus Renal cancer:8.44e-5 (favourable) Expressed in all Expressed in all fallopian tube: 21.1 INTS6 DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2 ENSG00000102786 Integrator complex subunit 6 13 51354077-51454264 Predicted intracellular proteins Evidence at protein level HPA001552, HPA001846 Supported Supported Nucleoplasm
Actin filaments Expressed in all Expressed in all testis: 106.4 INTS8 C8orf52, FLJ20530, INT8, MGC131633 ENSG00000164941 Integrator complex subunit 8 8 94813311-94881746 Predicted intracellular proteins Evidence at protein level HPA057299 Approved Approved Nucleoplasm Renal cancer:0.00e+0 (unfavourable), Liver cancer:2.54e-6 (unfavourable) Expressed in all Expressed in all testis: 61.5 INTS9 CPSF2L, FLJ10871, RC-74 ENSG00000104299 Integrator complex subunit 9 8 28767661-28890242 Predicted intracellular proteins Evidence at protein level HPA051615, HPA066822 Validated Nucleoplasm Renal cancer:1.91e-5 (favourable), Lung cancer:7.71e-4 (favourable), Endometrial cancer:9.45e-4 (favourable) Expressed in all Expressed in all testis: 19.8 IP6K1 IHPK1, KIAA0263 ENSG00000176095 Inositol hexakisphosphate kinase 1 3 49724294-49786542 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040825 Approved Supported Nucleus
Nucleoli fibrillar center
Cytosol Renal cancer:5.77e-5 (favourable), Head and neck cancer:2.08e-4 (favourable), Pancreatic cancer:6.85e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 47.6 IP6K2 IHPK2 ENSG00000068745 Inositol hexakisphosphate kinase 2 3 48688003-48740353 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007532 Approved Approved Nucleus
Intermediate filaments Breast cancer:1.25e-4 (favourable), Urothelial cancer:1.83e-4 (favourable), Lung cancer:2.95e-4 (favourable) Expressed in all Expressed in all epididymis: 128.7 IPO11 RanBP11 ENSG00000086200 Importin 11 5 62403972-62628582 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA067097 Approved Validated Nucleus
Nucleoli fibrillar center Liver cancer:4.28e-5 (unfavourable), Colorectal cancer:1.70e-4 (favourable) Expressed in all Expressed in all testis: 40.5 IPO13 IMP13, KIAA0724, RANBP13 ENSG00000117408 Importin 13 1 43946939-43968022 Predicted intracellular proteins, Transporters Evidence at protein level CAB070425 Uncertain Liver cancer:8.26e-7 (unfavourable), Pancreatic cancer:2.21e-4 (favourable) Expressed in all Expressed in all testis: 66.5 IPO5 IMB3, KPNB3, MGC2068, Pse1, RANBP5 ENSG00000065150 Importin 5 13 97953658-98024297 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB009110, HPA040983, HPA056548 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 382.6 IPO7 Imp7, RANBP7 ENSG00000205339 Importin 7 11 9384622-9448126 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA019002, HPA056590 Approved Approved Validated Nucleoplasm
Cytosol Pancreatic cancer:8.38e-6 (unfavourable), Cervical cancer:4.98e-4 (unfavourable), Liver cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 89.6 IPO8 IMP8, RANBP8 ENSG00000133704 Importin 8 12 30628988-30695986 Predicted intracellular proteins, Transporters Evidence at protein level HPA018439, HPA023765 Uncertain Supported Nucleus Renal cancer:8.62e-5 (favourable), Liver cancer:1.35e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 119.5 IPO9 FLJ10402, Imp9 ENSG00000198700 Importin 9 1 201829141-201884294 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA059540 Approved Vesicles
Cytosol Liver cancer:4.11e-5 (unfavourable), Renal cancer:2.86e-4 (unfavourable), Urothelial cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.0 IPP KLHL27 ENSG00000197429 Intracisternal A particle-promoted polypeptide 1 45694324-45750650 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:1.11e-4 (favourable), Liver cancer:2.27e-4 (unfavourable), Colorectal cancer:9.11e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 19.4 IQCB1 KIAA0036, NPHP5, SLSN5 ENSG00000173226 IQ motif containing B1 3 121769763-121835079 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042028 Supported Microtubules
Cytokinetic bridge
Mitotic spindle Liver cancer:3.08e-5 (unfavourable), Cervical cancer:1.77e-4 (favourable), Lung cancer:3.67e-4 (favourable) Expressed in all Expressed in all testis: 52.2 IQGAP1 HUMORFA01, KIAA0051, p195, SAR1 ENSG00000140575 IQ motif containing GTPase activating protein 1 15 90388218-90502243 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013302, HPA014055 Supported Supported Plasma membrane
Cell Junctions Pancreatic cancer:5.67e-5 (unfavourable) Expressed in all Expressed in all endometrium: 119.6 IQSEC1 ARF-GEP100, BRAG2, GEP100, KIAA0763 ENSG00000144711 IQ motif and Sec7 domain 1 3 12897220-13073117 Predicted intracellular proteins Evidence at protein level HPA038143, HPA038144 Uncertain Approved Nucleoli
Vesicles Renal cancer:3.58e-6 (favourable), Breast cancer:3.03e-5 (unfavourable), Pancreatic cancer:9.07e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 83.6 IRAK1 IRAK, pelle ENSG00000184216 Interleukin-1 receptor-associated kinase 1 X 154010500-154019980 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004461, HPA054476 Supported Supported Nucleus
Cytosol Renal cancer:2.06e-4 (unfavourable), Liver cancer:3.03e-4 (unfavourable) Expressed in all Expressed in all appendix: 52.6 IREB2 IRP2 ENSG00000136381 Iron-responsive element binding protein 2 15 78437431-78501456 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032885, HPA040371, HPA068982 Uncertain Approved Cell Junctions
Cytosol Expressed in all Expressed in all thyroid gland: 47.9 IRF1 MAR ENSG00000125347 Interferon regulatory factor 1 5 132481609-132490798 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011662, HPA063131 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.09e-7 (unfavourable) Expressed in all Expressed in all spleen: 137.5 IRF2 ENSG00000168310 Interferon regulatory factor 2 4 184387713-184474580 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030813, CAB032306, HPA057327 Supported Validated Nucleoplasm
Cytosol Breast cancer:6.95e-5 (favourable), Thyroid cancer:8.34e-5 (favourable) Expressed in all Expressed in all spleen: 75.4 IRF2BP1 DKFZP434M154, IRF-2BP1 ENSG00000170604 Interferon regulatory factor 2 binding protein 1 19 45883607-45886170 Predicted intracellular proteins Evidence at protein level HPA042164, HPA049480 Approved Supported Nucleoplasm Renal cancer:3.85e-5 (favourable), Pancreatic cancer:2.32e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 13.3 IRF2BP2 IRF-2BP2 ENSG00000168264 Interferon regulatory factor 2 binding protein 2 1 234604269-234609525 Predicted intracellular proteins Evidence at protein level HPA027815, HPA062269 Approved Validated Nucleoplasm Renal cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 98.9 IRF2BPL C14orf4, EAP1, KIAA1865 ENSG00000119669 Interferon regulatory factor 2 binding protein-like 14 77024543-77028699 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050862, HPA061333 Approved Validated Nucleoplasm Endometrial cancer:5.52e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.1 IRF3 ENSG00000126456 Interferon regulatory factor 3 19 49659569-49665875 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004895, CAB013018 Approved Supported Cytosol Renal cancer:1.56e-7 (unfavourable), Urothelial cancer:3.61e-4 (favourable) Expressed in all Expressed in all lymph node: 47.9 IRF9 ISGF3G ENSG00000213928 Interferon regulatory factor 9 14 24161053-24166565 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001862 Approved Supported Cytosol Renal cancer:7.58e-8 (unfavourable), Urothelial cancer:9.92e-4 (favourable) Expressed in all Expressed in all spleen: 96.0 ISCA1 HBLD2, hIscA, ISA1, MGC4276 ENSG00000135070 Iron-sulfur cluster assembly 1 9 86264546-86282538 Predicted intracellular proteins Evidence at protein level HPA042789 Uncertain Renal cancer:3.83e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 73.6 ISCA2 HBLD1, ISA2 ENSG00000165898 Iron-sulfur cluster assembly 2 14 74493720-74497106 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030492 Approved Renal cancer:1.68e-7 (favourable), Thyroid cancer:8.98e-5 (favourable) Expressed in all Expressed in all epididymis: 55.6 ISCU hnifU, IscU, ISU2, NIFUN ENSG00000136003 Iron-sulfur cluster assembly enzyme 12 108562582-108569384 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB006329, HPA038602, HPA057592 Approved Supported Cytosol Renal cancer:2.73e-7 (favourable), Cervical cancer:4.90e-7 (favourable), Urothelial cancer:6.12e-4 (favourable) Expressed in all Expressed in all adrenal gland: 401.0 ISG15 G1P2, IFI15, UCRP ENSG00000187608 ISG15 ubiquitin-like modifier 1 1001138-1014541 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004627 Approved Renal cancer:5.11e-10 (unfavourable) Expressed in all Expressed in all salivary gland: 113.1 ISG20L2 FLJ12671 ENSG00000143319 Interferon stimulated exonuclease gene 20kDa-like 2 1 156721891-156728799 Predicted intracellular proteins Evidence at protein level HPA028005, HPA054285 Approved Supported Nucleoplasm Renal cancer:4.80e-5 (unfavourable), Liver cancer:6.15e-5 (unfavourable), Endometrial cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 85.7 ISOC1 CGI-111 ENSG00000066583 Isochorismatase domain containing 1 5 129094751-129114028 Predicted intracellular proteins Evidence at protein level HPA070307 Approved Endoplasmic reticulum
Vesicles Expressed in all Expressed in all endometrium: 174.3 ISOC2 FLJ23469 ENSG00000063241 Isochorismatase domain containing 2 19 55452985-55462343 Predicted intracellular proteins Evidence at protein level HPA043142 Supported Approved Mitochondria
Cytosol Expressed in all Expressed in all kidney: 62.9 IST1 KIAA0174 ENSG00000182149 Increased sodium tolerance 1 homolog (yeast) 16 71845996-71931199 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041802, HPA054532 Approved Supported Vesicles Renal cancer:4.55e-4 (favourable), Urothelial cancer:8.88e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 174.9 ISY1 fSAP33, KIAA1160 ENSG00000240682 ISY1 splicing factor homolog 3 129127415-129161293 Predicted intracellular proteins Evidence at protein level HPA006312, HPA016995 Supported Validated Nuclear speckles Cervical cancer:2.46e-5 (favourable), Liver cancer:7.25e-4 (unfavourable) Expressed in all Expressed in all lymph node: 37.0 ISY1-RAB43 ENSG00000261796 ISY1-RAB43 readthrough 3 129087575-129161036 Predicted intracellular proteins Evidence at protein level HPA006312, HPA016995 Approved Validated Nuclear speckles Not detected Expressed in all appendix,parathyroid gland: 13.9 ITCH AIP4 ENSG00000078747 Itchy E3 ubiquitin protein ligase 20 34363235-34511393 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021126, HPA049032 Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 58.8 ITFG1 CDA08, LNKN-1, TIP ENSG00000129636 Integrin alpha FG-GAP repeat containing 1 16 47154387-47464149 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015590, HPA019728 Approved Approved Intermediate filaments
Aggresome Renal cancer:1.95e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 108.2 ITFG2 MDS028 ENSG00000111203 Integrin alpha FG-GAP repeat containing 2 12 2812622-2859791 Predicted intracellular proteins Evidence at protein level HPA038664, HPA038665 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Cytokinetic bridge Expressed in all Expressed in all thyroid gland: 45.8 ITGA5 CD49e, FNRA ENSG00000161638 Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 12 54395261-54419460 Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA002642, CAB009008 Supported Renal cancer:1.32e-8 (unfavourable), Cervical cancer:4.07e-6 (unfavourable), Liver cancer:2.23e-5 (unfavourable), Lung cancer:2.44e-4 (unfavourable), Head and neck cancer:2.91e-4 (unfavourable), Colorectal cancer:8.43e-4 (unfavourable), Thyroid cancer:8.89e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 482.6 ITGA6 CD49f ENSG00000091409 Integrin, alpha 6 2 172427354-172506282 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB009009, HPA012696, HPA027582 Supported Renal cancer:2.35e-11 (favourable), Head and neck cancer:1.03e-4 (unfavourable) Expressed in all Expressed in all placenta: 114.3 ITGAV CD51, MSK8, VNRA, VTNR ENSG00000138448 Integrin, alpha V 2 186590065-186680901 Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002499, HPA004856 Supported Approved Focal adhesion sites
Cytosol Stomach cancer:1.05e-6 (unfavourable), Liver cancer:2.08e-4 (unfavourable), Pancreatic cancer:5.07e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 187.7 ITGB1 CD29, FNRB, GPIIA, MDF2, MSK12 ENSG00000150093 Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 10 32900319-33005792 Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB003434 Approved Supported Endoplasmic reticulum
Plasma membrane
Focal adhesion sites Lung cancer:3.36e-6 (unfavourable), Cervical cancer:5.01e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 1058.2 ITGB1BP1 ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B ENSG00000119185 Integrin beta 1 binding protein 1 2 9403475-9423547 Predicted intracellular proteins Evidence at protein level HPA071538 Supported Nucleoplasm
Cytosol Endometrial cancer:1.03e-5 (unfavourable), Liver cancer:4.67e-5 (unfavourable), Renal cancer:7.10e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 124.9 ITGB2 CD18, LFA-1, MAC-1, MFI7 ENSG00000160255 Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 21 44885953-44931989 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008877, HPA016894 Supported Approved Cytosol Expressed in all Expressed in all appendix: 246.8 ITGB5 ENSG00000082781 Integrin, beta 5 3 124761948-124901418 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001820, CAB022050 Approved Approved Plasma membrane
Mitochondria Pancreatic cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all placenta: 116.8 ITM2A BRICD2A, E25A ENSG00000078596 Integral membrane protein 2A X 79360384-79367667 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002918 Uncertain Nucleoplasm Liver cancer:3.66e-6 (favourable) Expressed in all Expressed in all ovary: 219.0 ITM2B BRI, BRI2, BRICD2B, E25B, E3-16 ENSG00000136156 Integral membrane protein 2B 13 48233158-48270357 Disease related genes, Predicted membrane proteins Evidence at protein level HPA029292, HPA071992 Approved Validated Golgi apparatus
Vesicles Renal cancer:3.73e-5 (favourable) Expressed in all Expressed in all epididymis: 1826.9 ITM2C BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3 ENSG00000135916 Integral membrane protein 2C 2 230864639-230879248 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:1.81e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 854.9 ITPA C20orf37, dJ794I6.3, HLC14-06-P ENSG00000125877 Inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 20 3208868-3223870 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA022824 Approved Supported Cytosol Liver cancer:2.54e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 39.5 ITPK1 ENSG00000100605 Inositol-tetrakisphosphate 1-kinase 14 92936914-93116320 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055230 Approved Approved Mitochondria Endometrial cancer:8.56e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 93.4 ITPKB IP3-3KB, IP3KB ENSG00000143772 Inositol-trisphosphate 3-kinase B 1 226631690-226739323 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA030273, HPA072923 Uncertain Approved Nucleus Head and neck cancer:1.72e-5 (favourable), Lung cancer:6.65e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 61.8 ITPKC IP3-3KC, IP3KC ENSG00000086544 Inositol-trisphosphate 3-kinase C 19 40717103-40740860 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA050760, HPA053003 Approved Supported Nuclear speckles Lung cancer:4.91e-4 (unfavourable) Expressed in all Expressed in all esophagus: 69.5 ITPRIP bA127L20.2, DANGER, KIAA1754 ENSG00000148841 Inositol 1,4,5-trisphosphate receptor interacting protein 10 104309698-104338404 Predicted membrane proteins Evidence at protein level HPA043626 Uncertain Vesicles Lung cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 135.4 ITPRIPL2 FLJ22994, LOC162073, MGC126798, MGC126800 ENSG00000205730 Inositol 1,4,5-trisphosphate receptor interacting protein-like 2 16 19113932-19121629 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042011 Approved Centrosome Expressed in all Expressed in all skin: 27.9 ITSN1 ITSN, MGC134948, MGC134949, SH3D1A, SH3P17 ENSG00000205726 Intersectin 1 (SH3 domain protein) 21 33642400-33899861 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018007 Approved Supported Plasma membrane Expressed in all Expressed in all adipose tissue: 61.3 ITSN2 KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP ENSG00000198399 Intersectin 2 2 24202864-24360714 Predicted intracellular proteins Evidence at protein level HPA036475 Approved Approved Vesicles
Plasma membrane Head and neck cancer:2.98e-4 (favourable) Expressed in all Expressed in all thyroid gland: 84.6 IVD ACAD2 ENSG00000128928 Isovaleryl-CoA dehydrogenase 15 40405795-40435947 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041391, HPA044250 Supported Validated Nucleoplasm
Mitochondria Renal cancer:2.91e-9 (favourable), Liver cancer:1.95e-5 (favourable) Expressed in all Expressed in all thyroid gland: 151.3 IVNS1ABP HSPC068, KIAA0850, KLHL39, ND1, NS-1, NS1-BP ENSG00000116679 Influenza virus NS1A binding protein 1 185296388-185317329 Predicted intracellular proteins Evidence at protein level HPA003405 Approved Supported Cytosol Expressed in all Expressed in all bone marrow: 300.2 IWS1 DKFZp761G0123, FLJ10006, FLJ14655, FLJ32319 ENSG00000163166 IWS1 homolog (S. cerevisiae) 2 127436207-127526886 Predicted intracellular proteins Evidence at protein level HPA035719, HPA061866 Supported Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 43.4 JADE1 JADE-1, PHF17 ENSG00000077684 Jade family PHD finger 1 4 128809623-128875224 Predicted intracellular proteins Evidence at protein level HPA020016 Approved Approved Mitochondria Renal cancer:8.22e-6 (favourable) Expressed in all Expressed in all thyroid gland: 52.7 JADE2 JADE-2, KIAA0239, PHF15 ENSG00000043143 Jade family PHD finger 2 5 134524312-134583230 Predicted intracellular proteins Evidence at protein level HPA025959, HPA055789 Uncertain Validated Nucleoplasm Renal cancer:5.36e-6 (favourable), Ovarian cancer:4.42e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 47.6 JAG1 AGS, AHD, AWS, CD339, HJ1, JAGL1 ENSG00000101384 Jagged 1 20 10637684-10674107 CD markers, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB010343, HPA021555 Supported Supported Golgi apparatus
Plasma membrane Pancreatic cancer:4.10e-6 (unfavourable) Expressed in all Expressed in all placenta: 96.3 JAGN1 FLJ14602, GL009 ENSG00000171135 Jagunal homolog 1 3 9890554-9894349 Disease related genes, Predicted membrane proteins Evidence at protein level HPA067610 Approved Vesicles Expressed in all Expressed in all epididymis: 37.2 JAK1 JAK1A, JAK1B, JTK3 ENSG00000162434 Janus kinase 1 1 64833229-64966504 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013088 Approved Renal cancer:2.67e-4 (favourable), Colorectal cancer:2.81e-4 (favourable), Breast cancer:9.63e-4 (favourable) Expressed in all Expressed in all lymph node: 117.1 JAM3 JAM-C, JAMC ENSG00000166086 Junctional adhesion molecule 3 11 134068925-134152001 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003417, HPA050434 Uncertain Validated Golgi apparatus Urothelial cancer:2.68e-4 (unfavourable), Renal cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all placenta: 143.3 JAZF1 DKFZp761K2222, TIP27, ZNF802 ENSG00000153814 JAZF zinc finger 1 7 27830573-28180743 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB019271, HPA066967 Approved Supported Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all adrenal gland: 113.6 JCHAIN IGCJ, IGJ, JCH ENSG00000132465 Joining chain of multimeric IgA and IgM 4 70655541-70681817 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB034436, HPA044132 Supported Head and neck cancer:7.56e-7 (favourable), Breast cancer:1.81e-6 (favourable), Renal cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all colon: 7111.0 JDP2 JUNDM2 ENSG00000140044 Jun dimerization protein 2 14 75427716-75474111 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059511 Supported Approved Nucleoplasm
Nuclear speckles Colorectal cancer:8.58e-5 (unfavourable) Expressed in all Expressed in all spleen: 87.3 JKAMP C14orf100, CDA06, HSPC213, HSPC327, JAMP ENSG00000050130 JNK1/MAPK8-associated membrane protein 14 59484443-59505410 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA031172, HPA071650 Supported Approved Nucleoplasm
Vesicles Liver cancer:3.09e-6 (unfavourable), Renal cancer:1.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 74.7 JMJD1C DKFZp761F0118, FLJ14374, KIAA1380, TRIP8 ENSG00000171988 Jumonji domain containing 1C 10 63167221-63521850 Predicted intracellular proteins Evidence at protein level HPA056175, HPA066195 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 52.5 JMJD4 FLJ12517 ENSG00000081692 Jumonji domain containing 4 1 227730425-227735411 Predicted intracellular proteins Evidence at protein level HPA027260, HPA052861 Uncertain Approved Vesicles
Plasma membrane Renal cancer:3.16e-4 (unfavourable) Expressed in all Expressed in all testis: 12.9 JMJD6 KIAA0585, PTDSR, PTDSR1 ENSG00000070495 Jumonji domain containing 6 17 76712832-76726799 Predicted intracellular proteins Evidence at protein level CAB004548, HPA059156 Supported Supported Nucleoplasm Renal cancer:7.59e-7 (unfavourable), Liver cancer:5.75e-6 (unfavourable), Pancreatic cancer:5.71e-4 (favourable) Expressed in all Expressed in all bone marrow: 81.1 JMJD7 ENSG00000243789 Jumonji domain containing 7 15 41828085-41837581 Predicted intracellular proteins Evidence at protein level HPA005726 Uncertain Approved Cytosol Not detected Expressed in all skin: 28.0 JMJD8 C16orf20 ENSG00000161999 Jumonji domain containing 8 16 681671-684528 Predicted secreted proteins Evidence at transcript level Expressed in all Expressed in all parathyroid gland: 59.8 JMY FLJ37870, WHAMM2 ENSG00000152409 Junction mediating and regulatory protein, p53 cofactor 5 79236189-79327215 Predicted intracellular proteins Evidence at protein level HPA037508, HPA043308 Uncertain Uncertain Nucleoplasm Renal cancer:3.03e-5 (favourable), Ovarian cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.2 JOSD1 KIAA0063 ENSG00000100221 Josephin domain containing 1 22 38685543-38701556 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001168 Uncertain Liver cancer:4.50e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 56.5 JOSD2 SBBI54 ENSG00000161677 Josephin domain containing 2 19 50505998-50511353 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:6.04e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 16.8 JRKL HHMJG ENSG00000183340 JRK-like 11 96389989-96507574 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046184 Uncertain Approved Vesicles Expressed in all Expressed in all parathyroid gland: 19.1 JTB hJT ENSG00000143543 Jumping translocation breakpoint 1 153974269-153977688 Cancer-related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA006514 Approved Approved Vesicles
Actin filaments Renal cancer:6.65e-9 (unfavourable), Ovarian cancer:7.87e-4 (favourable) Expressed in all Expressed in all epididymis: 114.3 JUN AP-1, c-Jun ENSG00000177606 Jun proto-oncogene 1 58780788-58784327 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003801, CAB007780, HPA059474 Supported Validated Nucleoplasm Expressed in all Expressed in all thyroid gland: 312.9 JUNB ENSG00000171223 Jun B proto-oncogene 19 12791496-12793315 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004464, HPA019149 Approved Validated Nucleoplasm Renal cancer:1.05e-4 (unfavourable), Ovarian cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 322.6 JUND AP-1 ENSG00000130522 Jun D proto-oncogene 19 18279760-18281622 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005268, HPA063029 Supported Supported Nucleus Breast cancer:6.15e-5 (favourable) Expressed in all Expressed in all bone marrow: 278.3 KANK2 ANKRD25, KIAA1518, MXRA3 ENSG00000197256 KN motif and ankyrin repeat domains 2 19 11164267-11197791 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA015643 Approved Renal cancer:8.73e-5 (unfavourable) Expressed in all Expressed in all endometrium: 438.4 KANSL2 C12orf41, FLJ20436, NSL2 ENSG00000139620 KAT8 regulatory NSL complex subunit 2 12 48653401-48682238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038497, HPA038498 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:4.32e-4 (favourable), Liver cancer:4.98e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 31.9 KANSL3 FLJ10081, KIAA1310, NSL3, Rcd1 ENSG00000114982 KAT8 regulatory NSL complex subunit 3 2 96593170-96642787 Predicted intracellular proteins Evidence at protein level HPA035017, HPA035018, HPA041280 Approved Validated Nucleus Liver cancer:5.34e-4 (unfavourable) Expressed in all Expressed in all testis: 28.2 KARS DFNB89, KARS1, KARS2 ENSG00000065427 Lysyl-tRNA synthetase 16 75627474-75648643 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041345, HPA041550 Supported Supported Cytosol Head and neck cancer:8.84e-6 (unfavourable) Expressed in all Expressed in all testis: 177.7 KAT2A GCN5, GCN5L2, PCAF-b ENSG00000108773 K(lysine) acetyltransferase 2A 17 42113108-42121358 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048958 Uncertain Renal cancer:1.41e-8 (unfavourable), Pancreatic cancer:3.57e-4 (favourable) Expressed in all Expressed in all skin: 10.9 KAT2B GCN5, GCN5L, P/CAF, PCAF ENSG00000114166 K(lysine) acetyltransferase 2B 3 20040023-20154404 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB004526, HPA055839 Supported Approved Nucleus Expressed in all Expressed in all parathyroid gland: 83.6 KAT5 cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5 ENSG00000172977 K(lysine) acetyltransferase 5 11 65711996-65719604 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016953 Approved Supported Nucleoplasm Renal cancer:1.10e-13 (favourable) Expressed in all Expressed in all parathyroid gland: 81.9 KAT6A MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220 ENSG00000083168 K(lysine) acetyltransferase 6A 8 41929479-42051990 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017023, HPA063266, HPA065052 Supported Approved Nucleoli
Nuclear speckles
Cytosol Expressed in all Expressed in all parathyroid gland: 33.9 KAT6B Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B ENSG00000156650 K(lysine) acetyltransferase 6B 10 74825582-75032622 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006104 Supported Approved Nucleus
Nuclear bodies Renal cancer:4.82e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.0 KAT7 HBO1, HBOA, MYST2, ZC2HC7 ENSG00000136504 K(lysine) acetyltransferase 7 17 49788555-49835030 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044470 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 106.4 KAT8 FLJ14040, hMOF, MOF, MYST1, ZC2HC8 ENSG00000103510 K(lysine) acetyltransferase 8 16 31115754-31131393 Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066324 Supported Nucleoplasm Lung cancer:6.34e-4 (favourable) Expressed in all Expressed in all ovary: 61.5 KATNA1 ENSG00000186625 Katanin p60 (ATPase containing) subunit A 1 6 149594873-149648972 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036207 Approved Supported Nucleus
Microtubule organizing center Liver cancer:3.57e-7 (unfavourable) Expressed in all Expressed in all testis: 80.4 KATNB1 ENSG00000140854 Katanin p80 (WD repeat containing) subunit B 1 16 57735730-57757250 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041165, HPA041839 Supported Supported Plasma membrane
Microtubules
Cytosol Liver cancer:3.93e-4 (unfavourable), Pancreatic cancer:8.44e-4 (favourable), Endometrial cancer:9.24e-4 (favourable) Expressed in all Expressed in all testis: 45.4 KATNBL1 C15orf29, FLJ22557 ENSG00000134152 Katanin p80 subunit B-like 1 15 34140674-34210096 Predicted intracellular proteins Evidence at protein level HPA062573 Approved Approved Nucleus
Midbody
Mitotic spindle Renal cancer:4.60e-5 (unfavourable) Expressed in all Expressed in all placenta: 46.5 KBTBD2 BKLHD1, DKFZP566C134 ENSG00000170852 Kelch repeat and BTB (POZ) domain containing 2 7 32868172-32894131 Predicted intracellular proteins Evidence at protein level HPA021133 Uncertain Approved Nucleus
Nucleoli fibrillar center Cervical cancer:1.89e-4 (unfavourable), Liver cancer:5.69e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 38.7 KBTBD4 BKLHD4, FLJ10450, HSPC252 ENSG00000123444 Kelch repeat and BTB (POZ) domain containing 4 11 47572197-47579015 Predicted intracellular proteins Evidence at protein level HPA037792, HPA037793 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:2.70e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 48.0 KCMF1 DEBT91, DKFZP434L1021, PCMF, ZZZ1 ENSG00000176407 Potassium channel modulatory factor 1 2 84971093-85059472 Predicted intracellular proteins Evidence at protein level HPA030383, HPA030384 Approved Validated Nucleoplasm
Cytosol Liver cancer:2.33e-7 (unfavourable), Renal cancer:4.18e-6 (unfavourable), Pancreatic cancer:6.10e-5 (unfavourable) Expressed in all Expressed in all testis: 123.9 KCTD10 BTBD28, MSTP028 ENSG00000110906 Potassium channel tetramerization domain containing 10 12 109448656-109477544 Predicted intracellular proteins Evidence at protein level HPA014273 Approved Supported Nucleoplasm
Cytosol Liver cancer:5.32e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 78.7 KCTD12 C13orf2, KIAA1778, PFET1 ENSG00000178695 Potassium channel tetramerization domain containing 12 13 76880166-76886390 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056987 Approved Mitochondria Renal cancer:1.14e-4 (favourable) Expressed in all Expressed in all fallopian tube: 121.6 KCTD15 MGC25497 ENSG00000153885 Potassium channel tetramerization domain containing 15 19 33795933-33815763 Predicted intracellular proteins Evidence at protein level HPA050822 Uncertain Approved Nucleoplasm
Golgi apparatus Renal cancer:3.65e-8 (unfavourable) Expressed in all Expressed in all skin: 86.4 KCTD18 6530404F10Rik, FLJ31322, FLJ37818 ENSG00000155729 Potassium channel tetramerization domain containing 18 2 200488952-200519784 Predicted intracellular proteins Evidence at protein level HPA045498, HPA058028 Approved Approved Mitochondria Expressed in all Expressed in all thyroid gland: 23.1 KCTD20 C6orf69, dJ108K11.3, MGC14254 ENSG00000112078 Potassium channel tetramerization domain containing 20 6 36442767-36491143 Predicted intracellular proteins Evidence at protein level HPA030092 Approved Approved Nuclear speckles
Endoplasmic reticulum Glioma:7.39e-4 (favourable), Renal cancer:8.02e-4 (unfavourable), Liver cancer:8.32e-4 (unfavourable), Thyroid cancer:9.31e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 46.7 KCTD3 NY-REN-45 ENSG00000136636 Potassium channel tetramerization domain containing 3 1 215567392-215621807 Predicted intracellular proteins Evidence at protein level HPA015142 Approved Approved Cytosol Renal cancer:8.94e-6 (unfavourable), Pancreatic cancer:4.71e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 104.2 KCTD5 FLJ20040 ENSG00000167977 Potassium channel tetramerization domain containing 5 16 2682475-2709030 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all lymph node: 23.4 KCTD6 KCASH3, MGC27385 ENSG00000168301 Potassium channel tetramerization domain containing 6 3 58492114-58502360 Predicted intracellular proteins Evidence at protein level HPA036100, HPA036101 Uncertain Approved Nucleoli
Mitochondria Liver cancer:4.57e-4 (unfavourable), Renal cancer:8.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 40.3 KCTD9 BTBD27, FLJ20038 ENSG00000104756 Potassium channel tetramerization domain containing 9 8 25427847-25458476 Predicted intracellular proteins Evidence at protein level HPA042468, HPA047902 Supported Nucleoplasm
Intermediate filaments
Cytosol Colorectal cancer:7.88e-4 (favourable) Expressed in all Expressed in all prostate: 27.8 KDELC2 MGC33424 ENSG00000178202 KDEL (Lys-Asp-Glu-Leu) containing 2 11 108472105-108498432 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039315, HPA039817, HPA066134 Uncertain Supported Nucleoplasm
Vesicles Urothelial cancer:6.27e-5 (unfavourable), Liver cancer:1.45e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 61.1 KDELR1 ERD2, ERD2.1, HDEL ENSG00000105438 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 19 48382570-48391553 Predicted membrane proteins, Transporters Evidence at protein level CAB017455 Approved Supported Golgi apparatus
Vesicles Liver cancer:1.61e-4 (unfavourable), Head and neck cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 259.3 KDELR2 ELP-1, ERD2.2 ENSG00000136240 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 7 6445953-6484242 Predicted membrane proteins Evidence at protein level HPA016459 Approved Renal cancer:6.79e-8 (unfavourable), Head and neck cancer:1.03e-5 (unfavourable), Glioma:8.16e-5 (unfavourable) Expressed in all Expressed in all placenta: 202.3 KDM1A AOF2, BHC110, KDM1, KIAA0601, LSD1 ENSG00000004487 Lysine (K)-specific demethylase 1A 1 23019448-23083689 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB005884, HPA053660 Supported Validated Nucleoplasm
Cytosol Liver cancer:4.47e-12 (unfavourable), Colorectal cancer:6.31e-4 (favourable) Expressed in all Expressed in all testis: 163.3 KDM1B AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2 ENSG00000165097 Lysine (K)-specific demethylase 1B 6 18155329-18223853 Predicted intracellular proteins Evidence at protein level HPA031269 Uncertain Approved Nucleus Colorectal cancer:6.94e-4 (favourable) Expressed in all Expressed in all thyroid gland: 64.8 KDM2A CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA ENSG00000173120 Lysine (K)-specific demethylase 2A 11 67119269-67258087 Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB012272, HPA044251 Supported Approved Nucleus Expressed in all Expressed in all testis: 59.8 KDM2B CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2 ENSG00000089094 Lysine (K)-specific demethylase 2B 12 121429097-121581015 Enzymes, Predicted intracellular proteins Evidence at protein level HPA071257 Uncertain Nucleoplasm Head and neck cancer:6.74e-6 (favourable), Pancreatic cancer:8.64e-4 (favourable) Expressed in all Expressed in all lymph node: 36.3 KDM3A JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA ENSG00000115548 Lysine (K)-specific demethylase 3A 2 86440647-86492716 Predicted intracellular proteins Evidence at protein level HPA055543, HPA065162 Validated Nucleoplasm Liver cancer:2.15e-6 (unfavourable), Renal cancer:5.25e-4 (unfavourable) Expressed in all Expressed in all testis: 93.2 KDM3B C5orf7, JMJD1B, KIAA1082, NET22 ENSG00000120733 Lysine (K)-specific demethylase 3B 5 138352596-138437028 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016610, HPA057202 Supported Validated Nucleoplasm Renal cancer:6.67e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 66.5 KDM4A JHDM3A, JMJD2, JMJD2A, KIAA0677, TDRD14A ENSG00000066135 Lysine (K)-specific demethylase 4A 1 43650158-43705515 Predicted intracellular proteins Evidence at protein level HPA007610 Uncertain Supported Nucleoli fibrillar center Liver cancer:1.39e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.6 KDM4B JMJD2B, KIAA0876, TDRD14B ENSG00000127663 Lysine (K)-specific demethylase 4B 19 4969113-5153595 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062872 Supported Nucleus
Cytosol Endometrial cancer:4.25e-7 (favourable), Melanoma:2.13e-4 (unfavourable), Colorectal cancer:2.74e-4 (unfavourable), Breast cancer:7.39e-4 (favourable) Expressed in all Expressed in all thyroid gland: 19.8 KDM4C GASC1, JMJD2C, KIAA0780, TDRD14C ENSG00000107077 Lysine (K)-specific demethylase 4C 9 6757641-7175648 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA069357 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 34.4 KDM5A JARID1A, RBBP2 ENSG00000073614 Lysine (K)-specific demethylase 5A 12 280129-389454 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006201 Approved Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 42.5 KDM5C DXS1272E, JARID1C, MRX13, SMCX, XE169 ENSG00000126012 Lysine (K)-specific demethylase 5C X 53191321-53225422 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038244, HPA046147 Validated Nucleoplasm
Cytosol Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 65.5 KDM6A UTX ENSG00000147050 Lysine (K)-specific demethylase 6A X 44873177-45112602 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000568, HPA001165, HPA002111 Supported Approved Nucleoli Expressed in all Expressed in all bone marrow: 41.1 KDM6B JMJD3, KIAA0346 ENSG00000132510 Lysine (K)-specific demethylase 6B 17 7839904-7854796 Predicted intracellular proteins Evidence at protein level HPA037988 Supported Approved Nuclear speckles Thyroid cancer:3.37e-4 (unfavourable), Renal cancer:6.07e-4 (favourable) Expressed in all Expressed in all appendix: 29.5 KDSR DHSR, FVT1, SDR35C1 ENSG00000119537 3-ketodihydrosphingosine reductase 18 63327726-63367510 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB003673, HPA044884 Approved Renal cancer:9.53e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 45.6 KEAP1 INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454 ENSG00000079999 Kelch-like ECH-associated protein 1 19 10486120-10503741 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA005558, CAB025337 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Cervical cancer:3.28e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 49.4 KHDRBS1 FLJ34027, p62, Sam68 ENSG00000121774 KH domain containing, RNA binding, signal transduction associated 1 1 32013829-32060850 Predicted intracellular proteins Evidence at protein level CAB005355, HPA051280, HPA056813 Supported Validated Nucleoplasm Liver cancer:3.68e-5 (unfavourable), Renal cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all endometrium: 133.5 KHNYN KIAA0323 ENSG00000100441 KH and NYN domain containing 14 24429286-24441834 Predicted intracellular proteins Evidence at protein level HPA003402 Uncertain Approved Nucleoplasm
Cytosol Cervical cancer:4.38e-4 (unfavourable), Glioma:9.44e-4 (unfavourable) Expressed in all Expressed in all placenta: 48.7 KHSRP FBP2, FUBP2, KSRP ENSG00000088247 KH-type splicing regulatory protein 19 6413348-6424794 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034739, HPA056518 Supported Validated Nucleoplasm Renal cancer:2.56e-4 (unfavourable) Expressed in all Expressed in all testis: 179.2 KIAA0040 ENSG00000235750 KIAA0040 1 175156987-175192999 Predicted intracellular proteins Evidence at protein level HPA016895, HPA068812 Approved Approved Nucleoplasm Expressed in all Expressed in all placenta: 142.4 KIAA0100 BCOX, BCOX1, CT101, DKFZp686M0843, MGC111488 ENSG00000007202 KIAA0100 17 28614440-28645454 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042781 Uncertain Approved Nuclear speckles
Cytosol Liver cancer:3.47e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 90.6 KIAA0141 DELE ENSG00000081791 KIAA0141 5 141923808-141942047 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036548, HPA061490 Uncertain Uncertain Nucleoplasm
Golgi apparatus Ovarian cancer:6.89e-4 (unfavourable) Expressed in all Expressed in all spleen: 63.3 KIAA0196 SPG8 ENSG00000164961 KIAA0196 8 125024260-125091840 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034216, CAB034219, HPA064649, HPA070916 Supported Supported Nucleoplasm Liver cancer:6.74e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.2 KIAA0232 ENSG00000170871 KIAA0232 4 6781375-6884170 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036891, HPA036892, HPA061498 Approved Approved Cytosol Renal cancer:3.91e-10 (favourable) Expressed in all Expressed in all cerebral cortex: 38.3 KIAA0319L KIAA1837 ENSG00000142687 KIAA0319-like 1 35433490-35557950 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA072692 Approved Nucleoli
Golgi apparatus Liver cancer:5.92e-5 (unfavourable), Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 82.6 KIAA0355 ENSG00000166398 KIAA0355 19 34254537-34355586 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014570 Uncertain Approved Nucleoplasm Melanoma:2.82e-4 (unfavourable) Expressed in all Expressed in all placenta: 33.0 KIAA0368 ECM29, FLJ22036 ENSG00000136813 KIAA0368 9 111360692-111484745 Predicted intracellular proteins Evidence at protein level HPA021646, HPA059795 Uncertain Supported Nucleus Expressed in all Expressed in all parathyroid gland: 79.3 KIAA0391 MRPP3, PRORP ENSG00000100890 KIAA0391 14 35121846-35277614 Predicted intracellular proteins Evidence at protein level HPA020459 Approved Supported Nucleus
Mitochondria Mixed Expressed in all parathyroid gland: 42.5 KIAA0430 LKAP, Marf1, PPP1R34 ENSG00000166783 KIAA0430 16 15594386-15643166 Predicted intracellular proteins Evidence at protein level HPA017992 Approved Supported Golgi apparatus
Vesicles Expressed in all Expressed in all parathyroid gland: 20.2 KIAA0907 BLOM7 ENSG00000132680 KIAA0907 1 155913043-155934400 Predicted intracellular proteins Evidence at protein level HPA008796 Approved Approved Nucleoplasm Renal cancer:2.78e-10 (unfavourable), Liver cancer:1.01e-6 (unfavourable), Urothelial cancer:4.36e-5 (favourable), Prostate cancer:3.87e-4 (unfavourable) Expressed in all Expressed in all epididymis: 54.4 KIAA0922 DKFZp586H1322, TMEM131L ENSG00000121210 KIAA0922 4 153466346-153636711 Predicted membrane proteins Evidence at protein level HPA043472, HPA048443 Uncertain Approved Nucleoli fibrillar center
Vesicles Cervical cancer:6.69e-6 (favourable) Expressed in all Expressed in all lymph node: 57.0 KIAA0930 bK268H5.C22.1, C22orf9 ENSG00000100364 KIAA0930 22 45190338-45240769 Predicted intracellular proteins Evidence at protein level HPA038091 Uncertain Approved Nuclear membrane
Mitochondria Liver cancer:6.90e-8 (unfavourable), Renal cancer:8.95e-7 (unfavourable), Endometrial cancer:9.22e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 76.4 KIAA1033 SWIP ENSG00000136051 KIAA1033 12 105107324-105169134 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045666, HPA046737 Uncertain Validated Nucleoplasm Cervical cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all lymph node: 51.8 KIAA1109 FLJ21404, FSA, KIAA1371, Tweek ENSG00000138688 KIAA1109 4 122152333-122362758 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038076 Approved Approved Nucleoplasm
Centrosome Renal cancer:4.33e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 128.4 KIAA1143 ENSG00000163807 KIAA1143 3 44737661-44761662 Predicted intracellular proteins Evidence at protein level HPA045018, HPA061799 Approved Approved Nucleus
Cytokinetic bridge Renal cancer:3.26e-6 (favourable), Colorectal cancer:3.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 15.1 KIAA1147 LCHN ENSG00000257093 KIAA1147 7 141656728-141702153 Predicted intracellular proteins Evidence at protein level HPA029467, HPA061437 Approved Approved Golgi apparatus Head and neck cancer:6.24e-4 (favourable), Renal cancer:8.01e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 21.2 KIAA1161 NET37 ENSG00000164976 KIAA1161 9 34366670-34376853 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060533, HPA067487 Approved Approved Mitochondria Renal cancer:1.20e-13 (favourable), Endometrial cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 29.4 KIAA1191 FLJ21022, p33MONOX ENSG00000122203 KIAA1191 5 176346061-176361968 Predicted intracellular proteins Evidence at protein level HPA044701, HPA048145 Uncertain Approved Nucleoplasm Renal cancer:9.94e-5 (favourable) Expressed in all Expressed in all kidney: 197.1 KIAA1328 ENSG00000150477 KIAA1328 18 36829106-37232172 Predicted intracellular proteins Evidence at protein level HPA040946 Approved Approved Nuclear speckles
Vesicles
Lipid droplets Mixed Expressed in all testis: 42.7 KIAA1429 DKFZP434I116, fSAP121 ENSG00000164944 KIAA1429 8 94487693-94553529 Predicted intracellular proteins Evidence at protein level HPA031530 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all testis: 30.0 KIAA1468 FLJ33841, HsT3308, HsT885 ENSG00000134444 KIAA1468 18 62187258-62307829 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039708, HPA040038 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all skin: 24.7 KIAA1551 C12orf35, FLJ10652, FLJ20696, UTA2-1 ENSG00000174718 KIAA1551 12 31959370-31993107 Predicted intracellular proteins Evidence at protein level HPA013816, HPA015622 Approved Supported Nucleoli
Intermediate filaments
Cytosol Renal cancer:5.04e-9 (unfavourable) Expressed in all Expressed in all ovary: 90.6 KIAA1715 LNP, LNP1, Ul, ulnaless ENSG00000144320 KIAA1715 2 175923892-176002839 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014205 Approved Supported Nucleoplasm
Endoplasmic reticulum Expressed in all Expressed in all testis: 45.8 KIAA2013 MGC33867, RP5-1077B9.1 ENSG00000116685 KIAA2013 1 11919591-11926428 Predicted membrane proteins Evidence at protein level HPA052677, HPA060536 Uncertain Approved Golgi apparatus
Cytosol Expressed in all Expressed in all small intestine: 69.5 KIAA2026 FLJ20375 ENSG00000183354 KIAA2026 9 5881596-6007901 Predicted intracellular proteins Evidence at protein level HPA002109 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:8.34e-4 (favourable) Expressed in all Expressed in all testis: 22.9 KIDINS220 ARMS ENSG00000134313 Kinase D-interacting substrate, 220kDa 2 8725278-8837630 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014790 Supported Approved Nucleoplasm Renal cancer:9.29e-6 (favourable), Lung cancer:9.64e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 99.9 KIF13A bA500C11.2 ENSG00000137177 Kinesin family member 13A 6 17759183-17987623 Predicted intracellular proteins Evidence at protein level HPA029253, HPA029254 Uncertain Liver cancer:5.06e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.2 KIF16B C20orf23, dJ971B4.1, FLJ20135, SNX23 ENSG00000089177 Kinesin family member 16B 20 16272104-16573433 Predicted intracellular proteins Evidence at protein level HPA051198 Approved Uncertain Mitochondria Renal cancer:7.61e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 43.3 KIF1B CMT2, CMT2A, HMSNII, KIAA0591, KLP ENSG00000054523 Kinesin family member 1B 1 10210805-10381603 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015177 Approved Uncertain Nucleoli fibrillar center
Cytosol Renal cancer:2.91e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 105.7 KIF1BP DKFZP586B0923, KBP, KIAA1279, TTC20 ENSG00000198954 KIF1 binding protein 10 68988721-69016982 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035538, HPA035539 Uncertain Renal cancer:2.60e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 55.6 KIF1C SAX2, SPAX2, SPG58 ENSG00000129250 Kinesin family member 1C 17 4997948-5028401 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024602, HPA045020 Approved Renal cancer:2.26e-9 (favourable) Expressed in all Expressed in all skeletal muscle: 193.6 KIF22 Kid, KNSL4, OBP-1, OBP-2 ENSG00000079616 Kinesin family member 22 16 29790719-29805385 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041076, HPA048213 Approved Approved Nuclear speckles Cervical cancer:3.87e-8 (favourable) Expressed in all Expressed in all bone marrow: 54.0 KIF2A HK2, KIF2 ENSG00000068796 Kinesin heavy chain member 2A 5 62306162-62537249 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004715, HPA004716 Approved Validated Nucleus
Nucleoli
Centrosome Liver cancer:3.17e-6 (unfavourable), Renal cancer:3.81e-5 (unfavourable), Colorectal cancer:1.70e-4 (favourable), Head and neck cancer:5.45e-4 (favourable) Expressed in all Expressed in all testis: 91.5 KIF3B FLA8, KIAA0359, KLP-11 ENSG00000101350 Kinesin family member 3B 20 32277664-32335011 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007119 Approved Uncertain Nucleoplasm
Nucleoli
Golgi apparatus Renal cancer:1.44e-12 (favourable) Expressed in all Expressed in all parathyroid gland: 79.3 KIF5B KNS, KNS1 ENSG00000170759 Kinesin family member 5B 10 32009010-32056431 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009846, HPA037589, HPA037590 Approved Validated Microtubule organizing center
Cytosol Expressed in all Expressed in all parathyroid gland: 184.2 KIF9 MGC104186 ENSG00000088727 Kinesin family member 9 3 47228026-47283451 Predicted intracellular proteins Evidence at protein level HPA022031, HPA022033, HPA030429 Approved Approved Nucleus
Nucleoli Renal cancer:5.95e-6 (favourable), Colorectal cancer:2.26e-4 (favourable) Expressed in all Expressed in all testis: 87.0 KIFAP3 FLA3, KAP-1, KAP3, SMAP ENSG00000075945 Kinesin-associated protein 3 1 169921326-170085208 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023738, HPA023742 Supported Expressed in all Expressed in all cerebral cortex: 106.4 KIFC2 ENSG00000167702 Kinesin family member C2 8 144466043-144474202 Predicted secreted proteins Evidence at protein level HPA029264 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all skin: 73.3 KIFC3 ENSG00000140859 Kinesin family member C3 16 57758217-57863053 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA021240 Uncertain Expressed in all Expressed in all skin: 98.9 KIZ C20orf19, HT013, NCRNA00153, PLK1S1 ENSG00000088970 Kizuna centrosomal protein 20 21125983-21246622 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.11e-8 (unfavourable), Endometrial cancer:4.45e-4 (favourable) Expressed in all Expressed in all testis: 81.9 KLC1 hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A ENSG00000126214 Kinesin light chain 1 14 103561896-103714249 Predicted intracellular proteins Evidence at protein level CAB009798, HPA044617, HPA052450 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:6.75e-4 (favourable), Renal cancer:7.17e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 469.3 KLC2 FLJ12387 ENSG00000174996 Kinesin light chain 2 11 66257294-66267860 Predicted intracellular proteins Evidence at protein level HPA040416, HPA040434 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Head and neck cancer:3.16e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 64.0 KLC4 bA387M24.3, KNSL8 ENSG00000137171 Kinesin light chain 4 6 43040777-43075099 Predicted intracellular proteins Evidence at protein level HPA030168, HPA030169 Supported Approved Mitochondria
Cytosol Renal cancer:6.99e-6 (favourable) Expressed in all Expressed in all duodenum: 72.0 KLF10 EGRA, TIEG, TIEG1 ENSG00000155090 Kruppel-like factor 10 8 102648779-102655902 Predicted intracellular proteins, Transcription factors Evidence at protein level Lung cancer:2.61e-5 (unfavourable) Expressed in all Expressed in all lung: 100.0 KLF11 MODY7, TIEG2, Tieg3 ENSG00000172059 Kruppel-like factor 11 2 10042849-10054836 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058276 Approved Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all Expressed in all testis: 57.1 KLF13 BTEB3, FKLF-2, NSLP1, RFLAT-1 ENSG00000169926 Kruppel-like factor 13 15 31326855-31435665 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level Renal cancer:2.37e-9 (favourable) Expressed in all Expressed in all bone marrow: 37.8 KLF2 LKLF ENSG00000127528 Kruppel-like factor 2 19 16324817-16327874 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055964 Approved Approved Nucleoplasm Liver cancer:8.55e-4 (favourable) Expressed in all Expressed in all adipose tissue: 115.7 KLF3 BKLF ENSG00000109787 Kruppel-like factor 3 (basic) 4 38664196-38701042 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049512, HPA065054 Supported Supported Nucleoplasm Renal cancer:4.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 62.2 KLF4 EZF, GKLF ENSG00000136826 Kruppel-like factor 4 (gut) 9 107484852-107490482 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002926 Supported Supported Nucleoplasm Renal cancer:3.93e-5 (favourable) Expressed in all Expressed in all esophagus: 129.0 KLF6 BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9 ENSG00000067082 Kruppel-like factor 6 10 3775996-3785281 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB013529, HPA069585 Supported Approved Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Renal cancer:2.28e-4 (favourable) Expressed in all Expressed in all thyroid gland: 321.3 KLF7 UKLF ENSG00000118263 Kruppel-like factor 7 (ubiquitous) 2 207074137-207167267 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA030490 Approved Approved Golgi apparatus Renal cancer:4.26e-4 (favourable) Expressed in all Expressed in all smooth muscle: 30.6 KLF9 BTEB1 ENSG00000119138 Kruppel-like factor 9 9 70384597-70414624 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029308 Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:6.59e-6 (favourable) Expressed in all Expressed in all smooth muscle: 88.0 KLHDC10 KIAA0265, slim ENSG00000128607 Kelch domain containing 10 7 130070510-130135720 Predicted intracellular proteins Evidence at protein level HPA020119 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 69.2 KLHDC2 HCLP-1, LCP ENSG00000165516 Kelch domain containing 2 14 49767608-49786385 Predicted intracellular proteins Evidence at protein level HPA000628 Approved Supported Nucleoplasm
Nuclear membrane
Nuclear bodies Renal cancer:2.75e-10 (favourable) Expressed in all Expressed in all thyroid gland: 47.0 KLHDC3 dJ20C7.3, hPeas, PEAS ENSG00000124702 Kelch domain containing 3 6 43014103-43021298 Predicted intracellular proteins Evidence at protein level HPA030131, HPA030132, HPA030133, HPA030134 Uncertain Supported Nucleoplasm Endometrial cancer:4.52e-4 (unfavourable), Pancreatic cancer:9.08e-4 (favourable), Cervical cancer:9.15e-4 (favourable) Expressed in all Expressed in all testis: 251.3 KLHDC4 DKFZp434G0522 ENSG00000104731 Kelch domain containing 4 16 87696485-87765992 Predicted intracellular proteins Evidence at protein level HPA041665 Approved Supported Nucleoli Pancreatic cancer:1.14e-4 (favourable), Urothelial cancer:1.69e-4 (favourable) Expressed in all Expressed in all lymph node: 19.3 KLHDC8B MGC35097 ENSG00000185909 Kelch domain containing 8B 3 49171611-49176486 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008463, HPA014467 Supported Validated Cytosol Lung cancer:1.47e-4 (favourable) Expressed in all Expressed in all adrenal gland: 70.3 KLHL12 C3IP1 ENSG00000117153 Kelch-like family member 12 1 202891100-202928636 Predicted intracellular proteins Evidence at protein level HPA071324 Supported Vesicles
Microtubule organizing center Expressed in all Expressed in all testis: 81.6 KLHL18 FLJ13703, KIAA0795 ENSG00000114648 Kelch-like family member 18 3 47282917-47346816 Predicted intracellular proteins Evidence at protein level HPA035027, HPA035028 Approved Approved Nucleoplasm
Nuclear bodies Liver cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all skin: 14.2 KLHL20 KHLHX, KLEIP ENSG00000076321 Kelch-like family member 20 1 173714941-173786702 Predicted intracellular proteins Evidence at protein level HPA025034, HPA053704 Approved Supported Golgi apparatus
Cytosol Expressed in all Expressed in all testis: 29.2 KLHL21 KIAA0469 ENSG00000162413 Kelch-like family member 21 1 6590724-6614607 Predicted intracellular proteins Evidence at protein level HPA051364, HPA059307 Uncertain Supported Centrosome Renal cancer:1.71e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 39.0 KLHL22 FLJ14360, KELCHL ENSG00000099910 Kelch-like family member 22 22 20441519-20495883 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.34e-8 (favourable), Pancreatic cancer:3.85e-6 (favourable), Endometrial cancer:4.88e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 34.9 KLHL23 FLJ37812, MGC22679, MGC2610 ENSG00000213160 Kelch-like family member 23 2 169694488-169776989 Predicted intracellular proteins Evidence at protein level HPA047593 Approved Nucleoplasm
Actin filaments Renal cancer:2.43e-5 (unfavourable), Liver cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all endometrium: 42.5 KLHL24 DRE1, FLJ20059 ENSG00000114796 Kelch-like family member 24 3 183635568-183684477 Predicted intracellular proteins Evidence at transcript level HPA056337 Uncertain Expressed in all Expressed in all parathyroid gland: 73.1 KLHL36 C16orf44, FLJ12543 ENSG00000135686 Kelch-like family member 36 16 84648525-84667686 Predicted intracellular proteins Evidence at protein level HPA023423 Approved Approved Cytosol Renal cancer:5.52e-10 (favourable), Pancreatic cancer:9.81e-5 (favourable) Expressed in all Expressed in all testis: 20.7 KLHL5 ENSG00000109790 Kelch-like family member 5 4 39045039-39126857 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013958 Approved Expressed in all Expressed in all seminal vesicle: 90.3 KLHL7 KLHL6, RP42, SBBI26 ENSG00000122550 Kelch-like family member 7 7 23105758-23177914 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029491, HPA029492 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:8.98e-5 (favourable), Liver cancer:7.96e-4 (unfavourable) Expressed in all Expressed in all testis: 75.7 KLHL8 KIAA1378 ENSG00000145332 Kelch-like family member 8 4 87160103-87240314 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013856, HPA017762 Approved Validated Nucleoplasm Renal cancer:1.53e-5 (favourable) Expressed in all Expressed in all epididymis: 72.6 KLHL9 FLJ13568, KIAA1354 ENSG00000198642 Kelch-like family member 9 9 21329671-21335380 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046039, HPA059901 Approved Approved Cytosol Renal cancer:9.43e-10 (favourable) Expressed in all Expressed in all thyroid gland: 26.9 KMT2A ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1 ENSG00000118058 Lysine (K)-specific methyltransferase 2A 11 118436490-118526832 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017794, CAB024270, HPA044910 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 31.1 KMT2B CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7 ENSG00000272333 Lysine (K)-specific methyltransferase 2B 19 35718019-35738878 Cancer-related genes, Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006487 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 28.8 KMT2C HALR, KIAA1506, MLL3 ENSG00000055609 Lysine (K)-specific methyltransferase 2C 7 152134922-152436005 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA074736 Supported Nucleoplasm Renal cancer:8.01e-6 (favourable) Expressed in all Expressed in all skin: 25.8 KMT2D ALR, CAGL114, MLL2, MLL4, TNRC21 ENSG00000167548 Lysine (K)-specific methyltransferase 2D 12 49018975-49059774 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035977 Approved Approved Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 45.7 KMT2E HDCMC04P, MLL5 ENSG00000005483 Lysine (K)-specific methyltransferase 2E 7 105014179-105114361 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022812, HPA056125 Approved Approved Renal cancer:3.80e-5 (unfavourable) Expressed in all Expressed in all endometrium: 52.2 KNOP1 101F10.1, C16orf88, FAM191A, TSG118 ENSG00000103550 Lysine-rich nucleolar protein 1 16 19701934-19718235 Predicted intracellular proteins Evidence at protein level HPA041079, HPA066169 Uncertain Supported Nucleoli
Cytosol Liver cancer:3.75e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.0 KPNA1 IPOA5, NPI-1, RCH2, SRP1 ENSG00000114030 Karyopherin alpha 1 (importin alpha 5) 3 122421949-122514945 Predicted intracellular proteins, Transporters Evidence at protein level HPA053627, HPA063426 Supported Validated Nucleus
Cytosol Endometrial cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.5 KPNA2 IPOA1, QIP2, RCH1, SRP1alpha ENSG00000182481 Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 17 68035519-68046842 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB015460, HPA041270 Supported Validated Nucleoplasm
Cytosol Renal cancer:1.26e-13 (unfavourable), Liver cancer:2.12e-10 (unfavourable), Urothelial cancer:2.19e-4 (unfavourable), Colorectal cancer:3.83e-4 (favourable), Lung cancer:5.77e-4 (unfavourable) Expressed in all Expressed in all testis: 347.6 KPNA3 hSRP1, IPOA4, SRP1gamma, SRP4 ENSG00000102753 Karyopherin alpha 3 (importin alpha 4) 13 49699307-49792921 Predicted intracellular proteins, Transporters Evidence at protein level HPA046852 Approved Approved Nucleoplasm
Cytosol Glioma:1.48e-4 (favourable), Cervical cancer:2.80e-4 (unfavourable), Renal cancer:3.81e-4 (unfavourable) Expressed in all Expressed in all testis: 49.6 KPNA4 IPOA3, MGC12217, MGC26703, QIP1, SRP3 ENSG00000186432 Karyopherin alpha 4 (importin alpha 3) 3 160494995-160565588 Predicted intracellular proteins, Transporters Evidence at protein level CAB034336, HPA043154, HPA045500 Supported Validated Nucleus Liver cancer:6.24e-7 (unfavourable), Pancreatic cancer:1.03e-6 (unfavourable), Endometrial cancer:8.59e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 36.6 KPNA6 FLJ11249, IPOA7, KPNA7, MGC17918 ENSG00000025800 Karyopherin alpha 6 (importin alpha 7) 1 32108038-32176568 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA018863 Supported Approved Nucleoplasm
Cytosol Liver cancer:9.28e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.5 KPNB1 IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97 ENSG00000108424 Karyopherin (importin) beta 1 17 47649476-47685505 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA029878, CAB034449, HPA050302 Supported Supported Nucleoplasm
Nuclear membrane
Cytosol Liver cancer:2.55e-7 (unfavourable), Renal cancer:8.43e-6 (unfavourable) Expressed in all Expressed in all testis: 218.3 KRAS KRAS1, KRAS2 ENSG00000133703 Kirsten rat sarcoma viral oncogene homolog 12 25204789-25250936 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA049830 Approved Renal cancer:2.75e-5 (favourable), Pancreatic cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all rectum: 34.1 KRBOX4 FLJ20344, ZNF673 ENSG00000147121 KRAB box domain containing 4 X 46446857-46497422 Predicted intracellular proteins Evidence at protein level HPA065295 Approved Nucleoplasm Renal cancer:1.98e-7 (unfavourable), Liver cancer:2.87e-6 (unfavourable), Lung cancer:4.67e-5 (favourable), Urothelial cancer:2.17e-4 (favourable) Expressed in all Expressed in all endometrium: 29.3 KRCC1 FLJ22333 ENSG00000172086 Lysine-rich coiled-coil 1 2 88027205-88055729 Predicted intracellular proteins Evidence at protein level HPA045618, HPA052666 Approved Approved Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 58.6 KRI1 FLJ12949 ENSG00000129347 KRI1 homolog 19 10553078-10566037 Predicted intracellular proteins Evidence at protein level HPA043110, HPA043574 Approved Validated Nucleoli Renal cancer:4.89e-10 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Colorectal cancer:9.37e-4 (unfavourable) Expressed in all Expressed in all appendix: 27.6 KRIT1 CAM, CCM1 ENSG00000001631 KRIT1, ankyrin repeat containing 7 92198969-92246166 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049606 Supported Uncertain Vesicles Expressed in all Expressed in all testis: 48.6 KRR1 HRB2, RIP-1 ENSG00000111615 KRR1, small subunit (SSU) processome component, homolog (yeast) 12 75490861-75511636 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043433, HPA051690 Approved Validated Nucleus
Nucleoli Expressed in all Expressed in all bone marrow: 39.6 KRTCAP2 KCP2 ENSG00000163463 Keratinocyte associated protein 2 1 155169408-155173475 Predicted membrane proteins Evidence at protein level Renal cancer:9.70e-11 (unfavourable) Expressed in all Expressed in all epididymis: 236.5 KSR1 KSR, RSU2 ENSG00000141068 Kinase suppressor of ras 1 17 27456714-27626438 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB009623, HPA011215 Uncertain Renal cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all placenta: 75.0 KTN1 CG1, KIAA0004 ENSG00000126777 Kinectin 1 (kinesin receptor) 14 55559072-55701526 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003178, CAB015331, HPA017876 Supported Validated Endoplasmic reticulum Renal cancer:1.01e-6 (favourable), Head and neck cancer:6.83e-5 (unfavourable), Liver cancer:3.76e-4 (unfavourable) Expressed in all Expressed in all testis: 269.6 KXD1 BORCS4, C19orf50, FLJ25480, KXDL, MGC2749 ENSG00000105700 KxDL motif containing 1 19 18557762-18569387 Predicted intracellular proteins Evidence at protein level HPA041507, HPA041599 Approved Approved Nucleoli fibrillar center
Centrosome
Cytosol Renal cancer:7.71e-10 (unfavourable), Liver cancer:8.46e-4 (unfavourable) Expressed in all Expressed in all appendix: 93.1 L3HYPDH C14orf149, FLJ25436 ENSG00000126790 L-3-hydroxyproline dehydratase (trans-) 14 59460363-59484430 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056694 Approved Uncertain Vesicles Renal cancer:1.72e-9 (unfavourable) Expressed in all Expressed in all testis: 31.9 L3MBTL2 dJ756G23.3, DKFZP761I141, H-l(3)mbt-l ENSG00000100395 L(3)mbt-like 2 (Drosophila) 22 41205205-41231271 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000815 Approved Nucleoplasm Cervical cancer:6.39e-5 (favourable), Endometrial cancer:4.37e-4 (favourable) Expressed in all Expressed in all fallopian tube: 30.2 LACTB FLJ14902, MRPL56 ENSG00000103642 Lactamase, beta 15 63121800-63142061 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036361, HPA036362 Supported Supported Mitochondria Expressed in all Expressed in all testis: 39.6 LACTB2 CGI-83 ENSG00000147592 Lactamase, beta 2 8 70635318-70669174 Predicted intracellular proteins Evidence at protein level HPA044391, HPA053040 Approved Supported Nucleus
Golgi apparatus
Cytosol Renal cancer:5.60e-4 (favourable) Expressed in all Expressed in all testis: 118.9 LAGE3 CVG5, DXS9879E, DXS9951E, ESO3, ITBA2 ENSG00000196976 L antigen family, member 3 X 154477769-154479257 Predicted intracellular proteins Evidence at protein level HPA036122, HPA036123 Approved Supported Nucleoplasm
Nuclear bodies Cervical cancer:5.29e-6 (favourable), Renal cancer:5.42e-5 (unfavourable), Liver cancer:8.63e-5 (unfavourable), Endometrial cancer:7.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 38.9 LAMB2 LAMS ENSG00000172037 Laminin, beta 2 (laminin S) 3 49121114-49133118 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000053, HPA001895, HPA050033, CAB078160 Supported Approved Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 203.5 LAMP1 CD107a ENSG00000185896 Lysosomal-associated membrane protein 1 13 113297241-113323672 CD markers, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB004260, HPA014750 Supported Renal cancer:4.15e-5 (favourable) Expressed in all Expressed in all thyroid gland: 210.9 LAMP2 CD107b ENSG00000005893 Lysosomal-associated membrane protein 2 X 120427827-120469365 CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB005272, HPA029100 Supported Expressed in all Expressed in all gallbladder: 223.9 LAMTOR1 C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1 ENSG00000149357 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 11 72085895-72103387 Predicted intracellular proteins Evidence at protein level HPA002997 Approved Supported Golgi apparatus
Vesicles
Plasma membrane Liver cancer:3.63e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 142.7 LAMTOR2 ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3 ENSG00000116586 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 1 156054752-156058510 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004126 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.10e-6 (unfavourable) Expressed in all Expressed in all epididymis: 83.7 LAMTOR3 MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3 ENSG00000109270 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 4 99878336-99894490 Predicted intracellular proteins Evidence at protein level HPA026858 Supported Renal cancer:1.75e-9 (favourable), Liver cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 57.0 LAMTOR4 C7orf59 ENSG00000188186 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 7 100148907-100155944 Predicted intracellular proteins Evidence at protein level HPA020998 Supported Validated Vesicles Breast cancer:2.48e-4 (favourable), Cervical cancer:6.08e-4 (favourable) Expressed in all Expressed in all skin: 314.2 LAMTOR5 HBXIP, MGC71071, XIP ENSG00000134248 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 1 110401249-110407942 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006812 Approved Supported Cytosol Liver cancer:2.60e-4 (unfavourable), Thyroid cancer:5.52e-4 (favourable), Ovarian cancer:7.23e-4 (favourable) Expressed in all Expressed in all kidney: 428.5 LANCL1 GPR69A, p40 ENSG00000115365 LanC lantibiotic synthetase component C-like 1 (bacterial) 2 210431249-210477652 Predicted intracellular proteins Evidence at protein level HPA034994 Approved Approved Microtubules Expressed in all Expressed in all cerebral cortex: 153.7 LAP3 LAP, LAPEP, PEPS ENSG00000002549 Leucine aminopeptidase 3 4 17577192-17607972 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029606, HPA029607 Supported Supported Nucleoplasm
Midbody
Cytosol Expressed in all Expressed in all appendix: 182.0 LAPTM4A HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp ENSG00000068697 Lysosomal protein transmembrane 4 alpha 2 20032650-20052028 Predicted membrane proteins Evidence at protein level HPA031402, HPA031404, HPA068554 Approved Approved Golgi apparatus
Vesicles
Plasma membrane Pancreatic cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 627.8 LAPTM4B LC27 ENSG00000104341 Lysosomal protein transmembrane 4 beta 8 97775057-97853013 Predicted membrane proteins, Transporters Evidence at protein level CAB020782, HPA068830 Uncertain Approved Golgi apparatus Liver cancer:2.70e-6 (unfavourable), Breast cancer:5.63e-4 (unfavourable), Head and neck cancer:5.70e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 134.9 LAPTM5 ENSG00000162511 Lysosomal protein transmembrane 5 1 30732469-30757820 Predicted membrane proteins, Transporters Evidence at protein level HPA051293 Approved Approved Cytosol Renal cancer:5.89e-5 (unfavourable), Cervical cancer:3.40e-4 (favourable) Expressed in all Expressed in all bone marrow: 801.2 LARP1 KIAA0731, LARP, MGC19556 ENSG00000155506 La ribonucleoprotein domain family, member 1 5 154712902-154817607 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015222, HPA051397, HPA054819 Supported Supported Nucleus
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all parathyroid gland: 150.6 LARP1B DKFZp434K245, DKFZp686E0316, FLJ10378, LARP2 ENSG00000138709 La ribonucleoprotein domain family, member 1B 4 128061268-128222931 Predicted intracellular proteins Evidence at protein level HPA036280, HPA036281 Approved Supported Nuclear bodies
Cytosol Renal cancer:5.13e-5 (favourable) Expressed in all Expressed in all testis: 102.5 LARP4 PP13296 ENSG00000161813 La ribonucleoprotein domain family, member 4 12 50392383-50480004 Predicted intracellular proteins Evidence at protein level HPA039306, HPA039673 Approved Validated Cytosol Expressed in all Expressed in all adrenal gland: 36.8 LARP4B KIAA0217, LARP5 ENSG00000107929 La ribonucleoprotein domain family, member 4B 10 806914-931705 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036566, HPA042738 Approved Validated Cytosol Liver cancer:1.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 38.0 LARP7 DKFZP564K112, HDCMA18P, PIP7S ENSG00000174720 La ribonucleoprotein domain family, member 7 4 112636964-112657592 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026842, HPA027930 Approved Supported Nucleoplasm
Cytosol Urothelial cancer:4.33e-4 (favourable) Expressed in all Expressed in all thyroid gland: 58.3 LARS FLJ10595, FLJ21788, HSPC192, LARS1, LEUS, RNTLS ENSG00000133706 Leucyl-tRNA synthetase 5 146113038-146182660 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036424, HPA040881 Supported Supported Nuclear bodies
Cytosol Liver cancer:3.78e-5 (unfavourable), Thyroid cancer:2.98e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 69.4 LARS2 KIAA0028, LEURS, MGC26121 ENSG00000011376 Leucyl-tRNA synthetase 2, mitochondrial 3 45388506-45549421 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035951, HPA045450, HPA066085 Approved Supported Nucleoplasm
Mitochondria Renal cancer:1.32e-11 (favourable), Colorectal cancer:1.71e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 18.9 LAS1L FLJ12525 ENSG00000001497 LAS1-like, ribosome biogenesis factor X 65512582-65534775 Predicted intracellular proteins Evidence at protein level HPA044431, HPA061463 Supported Approved Nucleoplasm
Microtubule organizing center
Cytosol Expressed in all Expressed in all parathyroid gland: 39.9 LASP1 Lasp-1, MLN50 ENSG00000002834 LIM and SH3 protein 1 17 38869859-38921770 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012072, CAB022049 Supported Supported Plasma membrane
Focal adhesion sites
Cytosol Liver cancer:2.41e-4 (unfavourable), Endometrial cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all small intestine: 185.0 LATS1 WARTS ENSG00000131023 Large tumor suppressor kinase 1 6 149658153-149718256 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031804 Approved Uncertain Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 23.2 LATS2 ENSG00000150457 Large tumor suppressor kinase 2 13 20973032-21061547 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039191, HPA049037 Approved Supported Microtubule organizing center
Cytosol Cervical cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all testis: 25.7 LBH ENSG00000213626 Limb bud and heart development 2 30231531-30323730 Predicted intracellular proteins Evidence at protein level HPA034669 Approved Approved Vesicles Stomach cancer:8.24e-4 (unfavourable) Expressed in all Expressed in all lung: 197.5 LBR DHCR14B, TDRD18 ENSG00000143815 Lamin B receptor 1 225401502-225428925 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049840, HPA062236 Supported Validated Nuclear membrane Liver cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all lymph node: 99.8 LCAT ENSG00000213398 Lecithin-cholesterol acyltransferase 16 67939750-67944131 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044767 Approved Nucleoplasm Liver cancer:4.21e-8 (favourable), Renal cancer:1.71e-4 (unfavourable), Colorectal cancer:8.50e-4 (unfavourable) Expressed in all Expressed in all liver: 105.3 LCLAT1 AGPAT8, ALCAT1, FLJ37965, LYCAT ENSG00000172954 Lysocardiolipin acyltransferase 1 2 30447226-30644225 Enzymes, Predicted membrane proteins Evidence at protein level HPA031880, HPA049217 Uncertain Supported Endoplasmic reticulum
Cytosol Liver cancer:8.72e-4 (unfavourable), Head and neck cancer:9.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.2 LCMT1 CGI-68, PPMT1 ENSG00000205629 Leucine carboxyl methyltransferase 1 16 25111729-25178231 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041559, HPA043530 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:7.53e-6 (favourable), Cervical cancer:2.78e-4 (favourable), Liver cancer:5.85e-4 (unfavourable) Expressed in all Expressed in all testis: 59.5 LCOR FLJ38026, KIAA1795, MLR2 ENSG00000196233 Ligand dependent nuclear receptor corepressor 10 96832260-96981043 Predicted intracellular proteins Evidence at protein level HPA031428, HPA031429, HPA077000 Approved Approved Nucleoplasm Urothelial cancer:2.16e-4 (favourable) Expressed in all Expressed in all bone marrow: 18.3 LCP1 CP64, L-PLASTIN, LC64P, PLS2 ENSG00000136167 Lymphocyte cytosolic protein 1 (L-plastin) 13 46125920-46211871 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019493, CAB020673 Supported Approved Plasma membrane
Actin filaments
Cytosol Expressed in all Expressed in all lymph node: 622.1 LCP2 SLP-76, SLP76 ENSG00000043462 Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 5 170246237-170298227 Predicted intracellular proteins Evidence at protein level CAB004574, HPA036396, HPA036397 Supported Renal cancer:6.22e-5 (unfavourable), Endometrial cancer:5.08e-4 (favourable) Expressed in all Expressed in all spleen: 127.7 LDB1 CLIM2, NLI ENSG00000198728 LIM domain binding 1 10 102107560-102120453 Predicted intracellular proteins Evidence at protein level HPA034488 Approved Approved Nucleoplasm Expressed in all Expressed in all skin: 158.5 LDHA ENSG00000134333 Lactate dehydrogenase A 11 18394388-18408425 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB015336 Approved Supported Vesicles
Cytosol Renal cancer:9.69e-9 (unfavourable), Liver cancer:3.26e-8 (unfavourable), Lung cancer:2.27e-6 (unfavourable), Pancreatic cancer:8.09e-6 (unfavourable), Cervical cancer:2.78e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 499.8 LDHB ENSG00000111716 Lactate dehydrogenase B 12 21635342-21757857 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004641, HPA019007 Supported Validated Cytosol Renal cancer:2.51e-4 (favourable) Expressed in all Expressed in all kidney: 1776.6 LDLR LDLCQ2 ENSG00000130164 Low density lipoprotein receptor 19 11089362-11133816 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA009647, HPA013159 Approved Pancreatic cancer:6.60e-5 (unfavourable), Urothelial cancer:3.43e-4 (unfavourable), Renal cancer:5.92e-4 (unfavourable) Expressed in all Expressed in all lung: 87.7 LDLRAP1 ARH, ARH2, DKFZp586D0624, FHCB1, FHCB2, MGC34705 ENSG00000157978 Low density lipoprotein receptor adaptor protein 1 1 25543580-25568886 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB003705, HPA050358 Approved Approved Microtubules Expressed in all Expressed in all spleen: 51.7 LDOC1L dJ1033E15.2, DKFZp761O17121, Mar6, Mart6 ENSG00000188636 Leucine zipper, down-regulated in cancer 1-like 22 44492572-44498298 Predicted intracellular proteins Evidence at protein level HPA005697 Approved Approved Nuclear speckles
Cytosol Expressed in all Expressed in all cerebral cortex: 42.5 LEMD2 dJ482C21.1, NET25 ENSG00000161904 LEM domain containing 2 6 33771202-33789136 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017340 Approved Validated Nuclear membrane Renal cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 68.5 LEMD3 MAN1 ENSG00000174106 LEM domain containing 3 12 65169571-65248327 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA025078, HPA076986 Uncertain Supported Nuclear membrane Renal cancer:2.30e-4 (favourable) Expressed in all Expressed in all testis: 28.8 LENG8 KIAA1932, MGC40108, pp13842 ENSG00000167615 Leukocyte receptor cluster (LRC) member 8 19 54448887-54462037 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042004, HPA042056, HPA061571 Uncertain Supported Nucleus Renal cancer:3.30e-7 (unfavourable), Urothelial cancer:2.73e-6 (favourable), Head and neck cancer:7.59e-4 (favourable) Expressed in all Expressed in all spleen: 167.8 LEO1 ENSG00000166477 LEO1 homolog, Paf1/RNA polymerase II complex component 15 51938025-51971806 Predicted intracellular proteins Evidence at protein level HPA040741, HPA040941 Supported Validated Nucleoplasm
Nucleoli fibrillar center Expressed in all Expressed in all parathyroid gland: 35.1 LEPROT FLJ90360, OB-RGRP, OBRGRP, VPS55 ENSG00000213625 Leptin receptor overlapping transcript 1 65420587-65436007 Predicted membrane proteins Evidence at protein level HPA069444 Approved Centrosome Expressed in all Expressed in all placenta: 79.7 LEPROTL1 my047, Vps55 ENSG00000104660 Leptin receptor overlapping transcript-like 1 8 30095398-30177208 Predicted membrane proteins Evidence at protein level HPA047911 Uncertain Renal cancer:1.94e-5 (unfavourable), Colorectal cancer:9.04e-4 (favourable) Expressed in all Expressed in all placenta: 119.4 LETM1 ENSG00000168924 Leucine zipper-EF-hand containing transmembrane protein 1 4 1811479-1856247 Predicted membrane proteins, Transporters Evidence at protein level HPA011029, HPA011100 Supported Validated Mitochondria Prostate cancer:1.77e-4 (unfavourable), Liver cancer:1.79e-4 (unfavourable), Renal cancer:8.90e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 16.3 LETMD1 HCCR1 ENSG00000050426 LETM1 domain containing 1 12 51047962-51060424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA074361 Supported Nucleoplasm
Mitochondria Urothelial cancer:3.16e-4 (favourable), Renal cancer:3.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 61.5 LFNG SCDO3 ENSG00000106003 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 7 2512529-2529177 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA069130 Approved Endometrial cancer:6.36e-4 (favourable) Expressed in all Expressed in all skin: 68.6 LGALS1 GBP ENSG00000100097 Lectin, galactoside-binding, soluble, 1 22 37675608-37679806 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000646, HPA000687, HPA001130, CAB002157 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.18e-10 (unfavourable), Endometrial cancer:2.36e-5 (favourable), Liver cancer:3.06e-4 (unfavourable), Urothelial cancer:5.10e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 1705.8 LGALS3 GALIG, LGALS2, MAC-2 ENSG00000131981 Lectin, galactoside-binding, soluble, 3 14 55124110-55145413 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003162, CAB005191 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all colon: 886.8 LGALS3BP 90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B ENSG00000108679 Lectin, galactoside-binding, soluble, 3 binding protein 17 78971238-78980109 Cancer-related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA000554, CAB002158 Supported Renal cancer:1.07e-6 (unfavourable) Expressed in all Expressed in all gallbladder: 324.9 LGALS8 PCTA-1 ENSG00000116977 Lectin, galactoside-binding, soluble, 8 1 236518000-236552981 Predicted intracellular proteins Evidence at protein level HPA012734, HPA030491 Approved Approved Plasma membrane Renal cancer:4.93e-7 (unfavourable), Lung cancer:9.40e-4 (favourable) Expressed in all Expressed in all testis: 101.8 LGALSL GRP, HSPC159 ENSG00000119862 Lectin, galactoside-binding-like 2 64453969-64461381 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046079 Approved Approved Nucleoplasm Liver cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all skin: 111.1 LGMN LGMN1, PRSC1 ENSG00000100600 Legumain 14 92703807-92748702 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000799, HPA001426 Supported Approved Cytosol Renal cancer:4.70e-4 (favourable) Expressed in all Expressed in all placenta: 357.3 LGR4 GPR48 ENSG00000205213 Leucine-rich repeat containing G protein-coupled receptor 4 11 27365961-27472775 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA030267, HPA054350 Uncertain Approved Microtubule organizing center Renal cancer:2.00e-7 (favourable) Expressed in all Expressed in all kidney: 55.7 LHPP HDHD2B ENSG00000107902 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase 10 124461834-124617888 Enzymes, Predicted intracellular proteins Evidence at protein level HPA009163, HPA009269 Supported Supported Nuclear speckles
Cytosol Expressed in all Expressed in all cerebral cortex: 70.8 LIAS LAS ENSG00000121897 Lipoic acid synthetase 4 39459000-39477653 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018842, HPA019076 Approved Approved Approved Nucleoplasm
Mitochondria Renal cancer:4.11e-7 (favourable) Expressed in all Expressed in all testis: 31.5 LIG3 LIG2 ENSG00000005156 Ligase III, DNA, ATP-dependent 17 34980494-35009743 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006723 Supported Supported Nucleoplasm Expressed in all Expressed in all testis: 38.5 LIMA1 EPLIN ENSG00000050405 LIM domain and actin binding 1 12 50175788-50283546 Predicted intracellular proteins Evidence at protein level HPA023871, HPA052645 Supported Validated Plasma membrane
Actin filaments
Focal adhesion sites
Cytosol Head and neck cancer:1.76e-6 (unfavourable), Renal cancer:2.79e-4 (favourable) Expressed in all Expressed in all rectum: 146.2 LIMD1 ENSG00000144791 LIM domains containing 1 3 45555394-45686338 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064220 Supported Nucleus
Focal adhesion sites Renal cancer:6.73e-5 (favourable) Expressed in all Expressed in all lung: 26.8 LIMK1 LIMK ENSG00000106683 LIM domain kinase 1 7 74082933-74122525 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028064, HPA028516 Approved Supported Nuclear speckles
Cytosol Renal cancer:6.63e-8 (unfavourable), Liver cancer:7.79e-6 (unfavourable), Colorectal cancer:4.95e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.6 LIMK2 ENSG00000182541 LIM domain kinase 2 22 31212239-31280080 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008183, CAB019313, HPA053882 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.57e-6 (unfavourable) Expressed in all Expressed in all skin: 71.0 LIMS1 PINCH, PINCH1 ENSG00000169756 LIM and senescent cell antigen-like domains 1 2 108534355-108687246 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058455, HPA061230 Approved Supported Focal adhesion sites
Cytosol Renal cancer:7.88e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 59.7 LIN37 F25965, lin-37, ZK418.4 ENSG00000267796 Lin-37 DREAM MuvB core complex component 19 35748361-35754519 Predicted intracellular proteins Evidence at protein level HPA043253, HPA047809 Uncertain Supported Nucleoplasm Renal cancer:1.62e-6 (unfavourable), Pancreatic cancer:1.67e-4 (favourable) Expressed in all Expressed in all ovary: 12.4 LIN7C FLJ11215, LIN-7-C, LIN-7C, Lin7c, MALS-3, VELI3 ENSG00000148943 Lin-7 homolog C (C. elegans) 11 27494576-27506773 Predicted intracellular proteins Evidence at protein level HPA051118 Approved Renal cancer:1.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 24.2 LINC00116 NCRNA00116 ENSG00000175701 Long intergenic non-protein coding RNA 116 2 110211529-110245420 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all skeletal muscle: 257.7 LINC00493 LOC388789 ENSG00000232388 Long intergenic non-protein coding RNA 493 20 18567347-18569563 Predicted membrane proteins Evidence at transcript level HPA068733 Approved Nucleoplasm
Cytosol Urothelial cancer:7.84e-5 (favourable) Expressed in all Expressed in all epididymis: 155.5 LINC01420 ENSG00000204272 Long intergenic non-protein coding RNA 1420 X 56729259-56818380 Predicted intracellular proteins Evidence at transcript level Endometrial cancer:3.14e-5 (unfavourable), Head and neck cancer:3.11e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.8 LINS1 LINS, WINS1 ENSG00000140471 Lines homolog 1 15 100559369-100603230 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038578, HPA038579 Approved Approved Nucleoplasm Expressed in all Expressed in all thyroid gland: 14.0 LIPA CESD, LAL ENSG00000107798 Lipase A, lysosomal acid, cholesterol esterase 10 89213569-89414557 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB034892, HPA057052 Supported Supported Vesicles Expressed in all Expressed in all spleen: 503.4 LIPT1 MGC12290, MGC13378 ENSG00000144182 Lipoyltransferase 1 2 99154955-99163157 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034802 Approved Urothelial cancer:9.60e-8 (favourable), Lung cancer:5.70e-4 (favourable) Expressed in all Expressed in all testis: 24.2 LITAF FLJ38636, PIG7, SIMPLE, TP53I7 ENSG00000189067 Lipopolysaccharide-induced TNF factor 16 11547722-11636381 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006960 Approved Supported Nucleoplasm
Vesicles
Cytosol Glioma:1.78e-4 (unfavourable), Testis cancer:6.25e-4 (unfavourable) Expressed in all Expressed in all appendix: 231.9 LIX1L MGC46719 ENSG00000271601 Limb and CNS expressed 1 like 1 145933423-145958001 Predicted intracellular proteins Evidence at protein level HPA046996, HPA063598 Uncertain Approved Cytosol Renal cancer:3.19e-5 (unfavourable), Liver cancer:1.61e-4 (unfavourable), Urothelial cancer:5.27e-4 (unfavourable) Expressed in all Expressed in all ovary: 45.7 LLPH C12orf31, hLLP, MGC14817 ENSG00000139233 LLP homolog, long-term synaptic facilitation (Aplysia) 12 66116555-66130768 Predicted intracellular proteins Evidence at protein level HPA048920, HPA058786 Validated Nucleoli Liver cancer:6.44e-7 (unfavourable) Expressed in all Expressed in all adrenal gland: 42.7 LMAN1 ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60 ENSG00000074695 Lectin, mannose-binding, 1 18 59327823-59359962 Disease related genes, Predicted membrane proteins Evidence at protein level HPA002320, CAB037163 Supported Uncertain Cytosol Expressed in all Expressed in all thyroid gland: 124.8 LMAN2 C5orf8, GP36B, VIP36 ENSG00000169223 Lectin, mannose-binding 2 5 177331562-177351852 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003927 Approved Renal cancer:8.53e-4 (unfavourable) Expressed in all Expressed in all epididymis: 162.0 LMBR1 ACHP, C7orf2, FLJ11665, ZRS ENSG00000105983 Limb development membrane protein 1 7 156668946-156893230 Disease related genes, Predicted membrane proteins Evidence at protein level HPA016592 Approved Approved Cytosol Renal cancer:1.44e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 45.4 LMBRD1 bA810I22.1, C6orf209, cblF, FLJ11240 ENSG00000168216 LMBR1 domain containing 1 6 69675802-69797111 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA019547 Uncertain Renal cancer:1.07e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 170.0 LMBRD2 DKFZp434H2226 ENSG00000164187 LMBR1 domain containing 2 5 36098412-36151961 Predicted membrane proteins Evidence at protein level HPA012165 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 25.5 LMF1 C16orf26, FLJ12681, FLJ22302, JFP11, TMEM112, TMEM112A ENSG00000103227 Lipase maturation factor 1 16 853634-981318 Disease related genes, Predicted membrane proteins Evidence at protein level Renal cancer:7.95e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 22.7 LMF2 TMEM112B, TMEM153 ENSG00000100258 Lipase maturation factor 2 22 50502949-50507691 Predicted membrane proteins Evidence at protein level HPA062626 Approved Approved Centrosome Cervical cancer:3.47e-4 (favourable) Expressed in all Expressed in all pancreas: 38.0 LMNA CMD1A, HGPS, LGMD1B, LMN1, LMNL1, PRO1 ENSG00000160789 Lamin A/C 1 156082573-156140089 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004022, HPA006660 Supported Expressed in all Expressed in all gallbladder: 344.5 LMNB2 LMN2 ENSG00000176619 Lamin B2 19 2427638-2456996 Predicted intracellular proteins Evidence at protein level CAB022593, HPA047863, HPA062477 Supported Supported Nuclear membrane Renal cancer:9.34e-5 (unfavourable), Prostate cancer:9.53e-5 (unfavourable), Liver cancer:1.32e-4 (unfavourable), Stomach cancer:3.98e-4 (favourable), Melanoma:5.88e-4 (unfavourable) Expressed in all Expressed in all appendix: 21.2 LMO4 ENSG00000143013 LIM domain only 4 1 87328468-87348923 Predicted intracellular proteins Evidence at protein level CAB022345, HPA045877, HPA061638 Approved Supported Nucleoplasm
Midbody ring Thyroid cancer:1.42e-4 (favourable), Ovarian cancer:1.47e-4 (favourable), Liver cancer:5.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 218.1 LMO7 FBX20, FBXO20, KIAA0858 ENSG00000136153 LIM domain 7 13 75620434-75859870 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020923, HPA050184 Approved Supported Actin filaments
Cytosol Renal cancer:7.75e-12 (favourable), Pancreatic cancer:3.51e-4 (unfavourable), Endometrial cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all lung: 269.8 LMTK2 AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100 ENSG00000164715 Lemur tyrosine kinase 2 7 98106885-98209633 Enzymes, Predicted membrane proteins Evidence at protein level HPA010657, HPA041836 Uncertain Approved Nuclear speckles
Plasma membrane
Microtubule organizing center
Cytosol Renal cancer:1.12e-7 (favourable), Ovarian cancer:8.03e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 28.0 LNX2 MGC46315, PDZRN1 ENSG00000139517 Ligand of numb-protein X 2 13 27545911-27620404 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040698 Approved Approved Vesicles
Plasma membrane Renal cancer:7.09e-13 (favourable) Expressed in all Expressed in all testis: 23.2 LONP1 hLON, LonHS, PIM1, PRSS15 ENSG00000196365 Lon peptidase 1, mitochondrial 19 5691834-5720572 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002034, HPA002192 Supported Validated Nucleus
Mitochondria Expressed in all Expressed in all adrenal gland: 141.1 LONP2 LONP, LONPL, MGC4840 ENSG00000102910 Lon peptidase 2, peroxisomal 16 48244296-48363122 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008862 Uncertain Renal cancer:6.71e-7 (favourable), Cervical cancer:4.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 79.5 LONRF1 FLJ23749, RNF191 ENSG00000154359 LON peptidase N-terminal domain and ring finger 1 8 12721894-12756073 Predicted intracellular proteins Evidence at protein level HPA023584, HPA024814 Uncertain Approved Plasma membrane
Centrosome
Cytosol Expressed in all Expressed in all skin: 30.8 LPAR6 P2RY5, P2Y5 ENSG00000139679 Lysophosphatidic acid receptor 6 13 48389567-48444704 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA028934, HPA076273 Approved Supported Vesicles
Plasma membrane Renal cancer:3.60e-4 (unfavourable), Lung cancer:6.22e-4 (favourable) Expressed in all Expressed in all placenta: 100.1 LPCAT3 C3F, MBOAT5, nessy, OACT5 ENSG00000111684 Lysophosphatidylcholine acyltransferase 3 12 6976186-7018510 Enzymes, Predicted membrane proteins Evidence at protein level Renal cancer:4.89e-5 (favourable) Expressed in all Expressed in all duodenum: 126.4 LPGAT1 FAM34A, FAM34A1, KIAA0205, NET8 ENSG00000123684 Lysophosphatidylglycerol acyltransferase 1 1 211743457-211830772 Predicted membrane proteins Evidence at protein level HPA008304 Approved Expressed in all Expressed in all thyroid gland: 43.0 LPIN1 KIAA0188 ENSG00000134324 Lipin 1 2 11677595-11827409 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038021 Approved Approved Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all testis: 101.7 LPP ENSG00000145012 LIM domain containing preferred translocation partner in lipoma 3 188153284-188890671 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA011133, HPA017342 Supported Validated Focal adhesion sites
Cytosol Expressed in all Expressed in all smooth muscle: 116.9 LPXN LDPL ENSG00000110031 Leupaxin 11 58526871-58578220 Predicted intracellular proteins Evidence at protein level HPA043741, CAB046478, HPA061441 Supported Validated Nuclear speckles
Focal adhesion sites
Cytosol Endometrial cancer:8.81e-4 (favourable) Expressed in all Expressed in all tonsil: 111.2 LRBA BGL, CDC4L, LAB300, LBA ENSG00000198589 LPS-responsive vesicle trafficking, beach and anchor containing 4 150264531-151015727 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019366, HPA023597 Approved Approved Golgi apparatus
Cytosol Renal cancer:2.22e-16 (favourable) Expressed in all Expressed in all parathyroid gland: 61.5 LRCH1 CHDC1, KIAA1016 ENSG00000136141 Leucine-rich repeats and calponin homology (CH) domain containing 1 13 46553168-46753040 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021536 Uncertain Approved Nucleoli
Actin filaments
Cytosol Renal cancer:1.04e-4 (favourable), Ovarian cancer:5.75e-4 (unfavourable), Cervical cancer:6.24e-4 (unfavourable), Lung cancer:6.67e-4 (unfavourable) Expressed in all Expressed in all endometrium: 26.6 LRCH3 MGC4126 ENSG00000186001 Leucine-rich repeats and calponin homology (CH) domain containing 3 3 197791226-197888436 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012380, HPA017299 Uncertain Validated Cytosol Liver cancer:2.95e-4 (unfavourable) Expressed in all Expressed in all testis: 26.2 LRCH4 LRN, LRRN1 ENSG00000077454 Leucine-rich repeats and calponin homology (CH) domain containing 4 7 100574011-100586153 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA037667, HPA037668 Supported Approved Nucleoplasm
Focal adhesion sites
Cytosol Colorectal cancer:1.61e-7 (unfavourable) Expressed in all Expressed in all spleen: 107.7 LRIF1 C1orf103, FLJ11269, RIF1 ENSG00000121931 Ligand dependent nuclear receptor interacting factor 1 1 110947185-110964079 Predicted intracellular proteins Evidence at protein level HPA044515 Uncertain Supported Nucleus
Microtubule organizing center Ovarian cancer:1.73e-4 (favourable) Expressed in all Expressed in all testis: 46.7 LRIG1 DKFZP586O1624, LIG-1, LIG1 ENSG00000144749 Leucine-rich repeats and immunoglobulin-like domains 1 3 66378797-66501263 Predicted membrane proteins Evidence at protein level HPA011846 Approved Approved Cytosol Lung cancer:3.01e-5 (favourable), Urothelial cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 59.8 LRP1 A2MR, APOER, APR, CD91, LRP, LRP1A ENSG00000123384 Low density lipoprotein receptor-related protein 1 12 57128493-57213351 Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004182, CAB018621, HPA022903 Supported Supported Nucleoli
Cytosol Urothelial cancer:1.29e-5 (unfavourable), Renal cancer:1.52e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 123.2 LRP10 DKFZP564C1940, LRP9, MGC8675, MST087, MSTP087 ENSG00000197324 Low density lipoprotein receptor-related protein 10 14 22871613-22881580 Predicted membrane proteins Evidence at protein level HPA000932 Approved Nucleus
Nucleoli Liver cancer:3.54e-7 (unfavourable), Renal cancer:6.31e-5 (favourable), Lung cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all esophagus: 180.2 LRP11 bA350J20.3, MANSC3 ENSG00000120256 Low density lipoprotein receptor-related protein 11 6 149818798-149864026 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA064002 Approved Mitochondria Breast cancer:2.31e-8 (unfavourable), Liver cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 88.0 LRP5 BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2 ENSG00000162337 Low density lipoprotein receptor-related protein 5 11 68312609-68449275 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013001, HPA030505 Approved Renal cancer:3.55e-10 (favourable) Expressed in all Expressed in all small intestine: 50.8 LRPAP1 A2MRAP, HBP44 ENSG00000163956 Low density lipoprotein receptor-related protein associated protein 1 4 3506376-3532559 Disease related genes, Predicted secreted proteins Evidence at protein level HPA008001, CAB025518 Supported Supported Validated Endoplasmic reticulum Renal cancer:4.67e-11 (favourable) Expressed in all Expressed in all placenta: 13.6 LRPPRC GP130, LRP130, LSFC ENSG00000138095 Leucine-rich pentatricopeptide repeat containing 2 43886508-43996005 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB033786, HPA036408, HPA036409 Supported Validated Mitochondria Liver cancer:2.31e-7 (unfavourable), Renal cancer:6.65e-6 (favourable), Endometrial cancer:1.72e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 78.8 LRRC14 KIAA0014, LRRC14A ENSG00000160959 Leucine rich repeat containing 14 8 144517992-144525178 Predicted intracellular proteins Evidence at protein level HPA021047 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:1.78e-4 (favourable) Expressed in all Expressed in all prostate: 25.0 LRRC28 FLJ34269, FLJ45242, MGC24976 ENSG00000168904 Leucine rich repeat containing 28 15 99251362-99390729 Predicted intracellular proteins Evidence at transcript level HPA039378, HPA040784, HPA066130 Approved Approved Nucleus
Golgi apparatus
Mitochondria Ovarian cancer:9.97e-5 (favourable), Cervical cancer:1.41e-4 (favourable) Expressed in all Expressed in all testis: 50.0 LRRC32 D11S833E, GARP ENSG00000137507 Leucine rich repeat containing 32 11 76657524-76670747 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:3.93e-5 (unfavourable), Urothelial cancer:2.64e-4 (unfavourable) Expressed in all Expressed in all placenta: 75.9 LRRC40 FLJ20331 ENSG00000066557 Leucine rich repeat containing 40 1 70144805-70205620 Predicted intracellular proteins Evidence at protein level HPA026564 Approved Approved Nucleoli Colorectal cancer:4.54e-4 (favourable) Expressed in all Expressed in all testis: 21.6 LRRC41 MUF1 ENSG00000132128 Leucine rich repeat containing 41 1 46261196-46303608 Predicted intracellular proteins Evidence at protein level HPA051941 Uncertain Approved Nucleoplasm
Nuclear bodies Liver cancer:1.66e-9 (unfavourable), Cervical cancer:5.50e-4 (unfavourable), Renal cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 68.8 LRRC42 MGC8974 ENSG00000116212 Leucine rich repeat containing 42 1 53946077-53968168 Predicted intracellular proteins Evidence at protein level HPA047458, HPA050537, HPA064581 Uncertain Validated Nucleoplasm Liver cancer:3.88e-5 (unfavourable), Lung cancer:6.02e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 38.9 LRRC47 KIAA1185, RP1-286D6.3 ENSG00000130764 Leucine rich repeat containing 47 1 3778558-3796504 Predicted intracellular proteins Evidence at protein level HPA008512, HPA012018 Supported Supported Nucleoli fibrillar center Renal cancer:2.75e-4 (favourable), Liver cancer:3.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 19.8 LRRC57 FLJ36812 ENSG00000180979 Leucine rich repeat containing 57 15 42537820-42548802 Predicted intracellular proteins Evidence at protein level HPA040894 Approved Approved Mitochondria
Cytosol Renal cancer:2.15e-4 (favourable) Expressed in all Expressed in all bone marrow: 14.9 LRRC58 ENSG00000163428 Leucine rich repeat containing 58 3 120324509-120349339 Predicted intracellular proteins Evidence at protein level HPA057574 Uncertain Approved Nucleus
Cytosol Liver cancer:4.98e-4 (unfavourable), Thyroid cancer:6.18e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 30.3 LRRC59 FLJ21675, PRO1855 ENSG00000108829 Leucine rich repeat containing 59 17 50375059-50397553 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030827, HPA030829 Supported Validated Endoplasmic reticulum Renal cancer:1.19e-6 (unfavourable), Liver cancer:3.12e-6 (unfavourable), Head and neck cancer:1.00e-5 (unfavourable), Urothelial cancer:1.90e-5 (unfavourable), Colorectal cancer:2.60e-4 (favourable), Pancreatic cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 91.6 LRRC8A FLJ10337, KIAA1437, LRRC8, SWELL1 ENSG00000136802 Leucine rich repeat containing 8 family, member A 9 128882112-128918039 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:5.27e-5 (favourable), Pancreatic cancer:3.83e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 89.9 LRRC8D FLJ10470, LRRC5 ENSG00000171492 Leucine rich repeat containing 8 family, member D 1 89821014-89936611 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014745 Approved Nucleoplasm
Mitochondria Endometrial cancer:3.21e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 36.0 LRRFIP1 FLAP-1, FLIIAP1, GCF-2, HUFI-1, TRIP ENSG00000124831 Leucine rich repeat (in FLII) interacting protein 1 2 237627576-237813682 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006979 Approved Supported Cytosol Expressed in all Expressed in all parathyroid gland: 123.5 LRRFIP2 HUFI-2 ENSG00000093167 Leucine rich repeat (in FLII) interacting protein 2 3 37052656-37183689 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035956, HPA042023 Uncertain Approved Plasma membrane
Actin filaments Cervical cancer:6.31e-4 (favourable) Expressed in all Expressed in all testis: 130.5 LRSAM1 CMT2P, FLJ31641 ENSG00000148356 Leucine rich repeat and sterile alpha motif containing 1 9 127451486-127503501 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021403, HPA021844, CAB037304 Supported Approved Cytosol Pancreatic cancer:6.78e-6 (favourable), Renal cancer:5.72e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 20.9 LRTOMT CFAP111, COMT2, DFNB63, LRRC51 ENSG00000184154 Leucine rich transmembrane and O-methyltransferase domain containing 11 72080331-72110782 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039949 Approved Approved Nucleoli
Microtubules Ovarian cancer:5.36e-4 (favourable), Endometrial cancer:7.70e-4 (favourable) Expressed in all Expressed in all testis: 137.8 LSG1 FLJ11301 ENSG00000041802 Large 60S subunit nuclear export GTPase 1 3 194640788-194672477 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037704, HPA037705 Approved Supported Nucleus
Nuclear bodies
Cytosol Liver cancer:3.21e-7 (unfavourable) Expressed in all Expressed in all testis: 24.8 LSM1 CASM, YJL124C ENSG00000175324 LSM1 homolog, mRNA degradation associated 8 38163321-38176730 Predicted intracellular proteins Evidence at protein level HPA024601 Supported Vesicles
Cytosol Expressed in all Expressed in all placenta: 35.5 LSM10 MGC15749 ENSG00000181817 LSM10, U7 small nuclear RNA associated 1 36391238-36397892 Predicted intracellular proteins Evidence at protein level HPA048469 Supported Nucleus
Nuclear bodies Renal cancer:6.40e-6 (unfavourable), Liver cancer:1.83e-4 (unfavourable), Pancreatic cancer:4.89e-4 (favourable) Expressed in all Expressed in all lymph node: 61.3 LSM12 FLJ30656 ENSG00000161654 LSM12 homolog 17 44034635-44067619 Predicted intracellular proteins Evidence at protein level HPA051934 Approved Approved Cytosol Renal cancer:1.18e-7 (unfavourable), Pancreatic cancer:7.49e-5 (unfavourable), Liver cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all testis: 49.0 LSM14B bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B ENSG00000149657 LSM family member 14B 20 62122461-62135378 Predicted intracellular proteins Evidence at protein level HPA041274, HPA061189 Approved Supported Nucleoli fibrillar center
Vesicles Liver cancer:3.61e-5 (unfavourable) Expressed in all Expressed in all testis: 78.8 LSM3 SMX4, USS2, YLR438C ENSG00000170860 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated 3 14178358-14201119 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044966 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all kidney: 21.0 LSM4 YER112W ENSG00000130520 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated 19 18306230-18323274 Predicted intracellular proteins Evidence at protein level HPA040932 Uncertain Approved Vesicles Ovarian cancer:1.34e-4 (favourable), Renal cancer:2.22e-4 (favourable) Expressed in all Expressed in all testis: 102.3 LSM5 YER146W ENSG00000106355 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated 7 32485332-32495283 Predicted intracellular proteins Evidence at protein level HPA019054 Uncertain Liver cancer:7.53e-5 (unfavourable), Renal cancer:1.84e-4 (unfavourable) Expressed in all Expressed in all breast: 76.9 LSM6 YDR378C ENSG00000164167 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated 4 146175685-146200000 Predicted intracellular proteins Evidence at protein level HPA045079 Approved Approved Actin filaments Melanoma:3.88e-4 (unfavourable), Renal cancer:6.65e-4 (unfavourable) Expressed in all Expressed in all lymph node: 42.6 LSM7 YNL147W ENSG00000130332 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated 19 2321517-2328620 Predicted intracellular proteins Evidence at protein level HPA041850 Uncertain Approved Nucleoli fibrillar center Endometrial cancer:4.19e-5 (favourable), Cervical cancer:3.28e-4 (favourable), Urothelial cancer:6.96e-4 (favourable) Expressed in all Expressed in all lymph node: 72.1 LSM8 YJR022W ENSG00000128534 LSM8 homolog, U6 small nuclear RNA associated 7 118184032-118192824 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020116 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:7.46e-6 (unfavourable), Endometrial cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all lymph node: 53.1 LSP1 WP34 ENSG00000130592 Lymphocyte-specific protein 1 11 1852970-1892267 Predicted intracellular proteins Evidence at protein level CAB017781, HPA019693, HPA071843 Supported Supported Plasma membrane Endometrial cancer:2.54e-4 (favourable), Cervical cancer:3.56e-4 (favourable), Glioma:9.00e-4 (unfavourable) Expressed in all Expressed in all spleen: 286.5 LSR ILDR3, LISCH7 ENSG00000105699 Lipolysis stimulated lipoprotein receptor 19 35248330-35267964 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007270 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:8.09e-4 (favourable) Expressed in all Expressed in all stomach: 131.1 LSS OSC ENSG00000160285 Lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 21 46188141-46228824 Enzymes, Predicted intracellular proteins Evidence at protein level HPA032060, HPA032062, CAB034116 Supported Approved Cytosol Urothelial cancer:3.07e-4 (unfavourable), Stomach cancer:6.80e-4 (unfavourable) Expressed in all Expressed in all prostate: 35.2 LTA4H ENSG00000111144 Leukotriene A4 hydrolase 12 96000828-96043520 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008399, CAB015221, HPA017017 Supported Supported Nucleoplasm
Cytosol Lung cancer:8.96e-4 (favourable), Breast cancer:9.79e-4 (favourable) Expressed in all Expressed in all lung: 283.6 LTBP1 ENSG00000049323 Latent transforming growth factor beta binding protein 1 2 32946972-33399509 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005707, CAB025428 Approved Approved Cytosol Renal cancer:7.79e-6 (unfavourable), Urothelial cancer:1.62e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 259.8 LTBP3 LTBP2 ENSG00000168056 Latent transforming growth factor beta binding protein 3 11 65538560-65558930 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA073170 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 102.2 LTBP4 FLJ46318, FLJ90018, LTBP-4, LTBP-4L ENSG00000090006 Latent transforming growth factor beta binding protein 4 19 40592883-40629818 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB015194 Approved Ovarian cancer:2.36e-4 (unfavourable) Expressed in all Expressed in all ovary: 245.0 LTBR D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3 ENSG00000111321 Lymphotoxin beta receptor (TNFR superfamily, member 3) 12 6375045-6391571 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026202 Uncertain Approved Golgi apparatus Liver cancer:5.13e-4 (unfavourable), Renal cancer:5.92e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 88.1 LTN1 C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294 ENSG00000198862 Listerin E3 ubiquitin protein ligase 1 21 28928144-28992956 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029143, CAB034164, HPA055604 Uncertain Validated Cytosol Expressed in all Expressed in all placenta: 26.4 LTV1 C6orf93, dJ468K18.4, FLJ14909 ENSG00000135521 LTV1 ribosome biogenesis factor 6 143843344-143863812 Predicted intracellular proteins Evidence at protein level HPA030159, HPA030160, HPA030161 Approved Validated Nucleoplasm
Cytosol Renal cancer:6.01e-13 (unfavourable), Liver cancer:4.95e-5 (unfavourable) Expressed in all Expressed in all testis: 38.4 LUC7L hLuc7B1, Luc7, LUC7B1 ENSG00000007392 LUC7-like 16 188969-229463 Predicted intracellular proteins Evidence at protein level HPA056424, HPA069321 Supported Approved Nucleus
Mitochondria Pancreatic cancer:1.30e-4 (favourable), Renal cancer:2.59e-4 (unfavourable) Expressed in all Expressed in all testis: 41.2 LUC7L2 CGI-59, CGI-74, FLJ10657, hLuc7B2, H_NH0792N18.3, LUC7B2 ENSG00000146963 LUC7-like 2 pre-mRNA splicing factor 7 139340359-139423457 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051631 Approved Approved Nucleus Renal cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 100.3 LUC7L3 CRA, CREAP-1, CROP, FLJ11063, hLuc7A, LUC7A, OA48-18 ENSG00000108848 LUC7-like 3 pre-mRNA splicing factor 17 50719544-50756213 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018475, HPA018484, HPA020017 Supported Validated Nuclear speckles Renal cancer:8.41e-7 (unfavourable), Liver cancer:1.05e-5 (unfavourable), Urothelial cancer:5.35e-5 (favourable), Pancreatic cancer:6.07e-4 (favourable) Expressed in all Expressed in all endometrium: 236.7 LUZP1 LUZP ENSG00000169641 Leucine zipper protein 1 1 23084023-23177808 Predicted intracellular proteins Evidence at protein level HPA028506, HPA028542 Supported Uncertain Vesicles
Actin filaments
Cytosol Renal cancer:1.46e-7 (favourable), Cervical cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 46.2 LXN ENSG00000079257 Latexin 3 158645822-158672693 Predicted intracellular proteins Evidence at protein level HPA014179, CAB025128 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.86e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 61.1 LY6E RIG-E, SCA-2, TSA-1 ENSG00000160932 Lymphocyte antigen 6 complex, locus E 8 143017982-143023832 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Renal cancer:6.74e-8 (unfavourable) Expressed in all Expressed in all lung: 109.5 LY6G5B C6orf19, G5b ENSG00000240053 Lymphocyte antigen 6 complex, locus G5B 6 31670167-31673776 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048307 Approved Mixed Expressed in all skin: 27.1 LYPLA1 LPL1 ENSG00000120992 Lysophospholipase I 8 54046367-54102017 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050941, HPA063151 Supported Uncertain Nucleoplasm
Cytosol Pancreatic cancer:2.34e-4 (unfavourable) Expressed in all Expressed in all testis: 118.0 LYPLA2 APT-2 ENSG00000011009 Lysophospholipase II 1 23790970-23795539 Predicted intracellular proteins Evidence at protein level HPA063151 Uncertain Nucleoplasm
Cytosol Liver cancer:5.84e-5 (unfavourable), Renal cancer:4.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 107.0 LYRM1 A211C6.1 ENSG00000102897 LYR motif containing 1 16 20899868-20925006 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059840 Supported Nucleoplasm
Midbody Endometrial cancer:7.48e-7 (favourable), Renal cancer:4.80e-4 (unfavourable), Urothelial cancer:9.50e-4 (favourable) Expressed in all Expressed in all testis: 70.0 LYRM2 DJ122O8.2 ENSG00000083099 LYR motif containing 2 6 89568144-89638753 Predicted intracellular proteins Evidence at protein level HPA063932 Uncertain Approved Cytosol Liver cancer:2.58e-8 (unfavourable) Expressed in all Expressed in all thyroid gland: 42.4 LYRM4 C6orf149, CGI-203, ISD11 ENSG00000214113 LYR motif containing 4 6 5102593-5260939 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030362 Approved Supported Nuclear bodies Expressed in all Expressed in all ovary: 30.0 LYRM5 ENSG00000205707 LYR motif containing 5 12 25195216-25209645 Predicted intracellular proteins Evidence at protein level HPA044255 Approved Approved Microtubule organizing center Renal cancer:9.23e-5 (favourable), Breast cancer:9.63e-4 (favourable) Expressed in all Expressed in all testis: 111.5 LYRM9 C17orf108, HSD24 ENSG00000232859 LYR motif containing 9 17 27878314-27894752 Predicted intracellular proteins Evidence at protein level HPA023051 Uncertain Renal cancer:5.41e-4 (favourable), Pancreatic cancer:9.46e-4 (favourable) Mixed Expressed in all thyroid gland: 71.7 LYSMD2 MGC35274 ENSG00000140280 LysM, putative peptidoglycan-binding, domain containing 2 15 51723011-51751585 Predicted intracellular proteins Evidence at protein level HPA040460 Approved Approved Nuclear bodies
Mitochondria Expressed in all Expressed in all cerebral cortex: 38.3 LYSMD3 FLJ13542 ENSG00000176018 LysM, putative peptidoglycan-binding, domain containing 3 5 90515611-90529584 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018024 Approved Approved Cytosol Colorectal cancer:3.83e-4 (favourable), Renal cancer:9.25e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.0 LYZ ENSG00000090382 Lysozyme 12 69348341-69354234 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level CAB000055, HPA048284 Supported Head and neck cancer:7.45e-4 (favourable) Expressed in all Expressed in all stomach: 9772.4 LZIC MGC15436 ENSG00000162441 Leucine zipper and CTNNBIP1 domain containing 1 9922113-9943407 Predicted intracellular proteins Evidence at protein level HPA028184, HPA058614 Approved Approved Nucleoplasm
Cytosol Liver cancer:2.47e-5 (unfavourable), Renal cancer:3.56e-5 (favourable) Expressed in all Expressed in all testis: 119.4 LZTR1 BTBD29, LZTR-1 ENSG00000099949 Leucine-zipper-like transcription regulator 1 22 20979462-20999038 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA068772, HPA071248 Approved Approved Nucleus Liver cancer:5.15e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.5 LZTS2 KIAA1813, LAPSER1 ENSG00000107816 Leucine zipper, putative tumor suppressor 2 10 100996618-101007836 Predicted intracellular proteins Evidence at protein level HPA044956 Approved Approved Plasma membrane
Cytosol Renal cancer:3.39e-4 (unfavourable), Colorectal cancer:8.23e-4 (unfavourable) Expressed in all Expressed in all endometrium: 57.8 M6PR ENSG00000003056 Mannose-6-phosphate receptor (cation dependent) 12 8940363-8949955 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB034464, HPA040445 Approved Liver cancer:3.89e-4 (unfavourable) Expressed in all Expressed in all spleen: 178.5 MACF1 ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF ENSG00000127603 Microtubule-actin crosslinking factor 1 1 39081316-39487177 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013713, HPA068064, HPA068103 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Renal cancer:2.77e-5 (favourable) Expressed in all Expressed in all lung: 137.3 MAD1L1 HsMAD1, MAD1, PIG9, TP53I9, TXBP181 ENSG00000002822 MAD1 mitotic arrest deficient-like 1 (yeast) 7 1815793-2233243 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003635, CAB015338 Supported Supported Nucleus
Actin filaments
Cytosol Expressed in all Expressed in all lymph node: 23.7 MAD2L1BP CMT2, dJ261G23.1, KIAA0110 ENSG00000124688 MAD2L1 binding protein 6 43629540-43640952 Predicted intracellular proteins Evidence at protein level HPA028729 Supported Nucleus
Nuclear membrane
Nucleoli Expressed in all Expressed in all bone marrow: 32.6 MAD2L2 MAD2B, POLZ2, REV7 ENSG00000116670 MAD2 mitotic arrest deficient-like 2 (yeast) 1 11674480-11691650 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB008110, HPA024176 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all testis: 73.5 MADD DENN, KIAA0358, RAB3GEP ENSG00000110514 MAP-kinase activating death domain 11 47269161-47330031 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038568 Uncertain Supported Plasma membrane
Cytosol Pancreatic cancer:5.69e-5 (favourable), Endometrial cancer:6.62e-5 (favourable), Urothelial cancer:8.25e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 104.2 MAEA EMP, GID9 ENSG00000090316 Macrophage erythroblast attacher 4 1289851-1340147 Predicted intracellular proteins Evidence at protein level HPA036886, HPA058185 Approved Validated Nucleoplasm Renal cancer:1.90e-4 (favourable), Head and neck cancer:5.34e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 38.2 MAF1 DKFZp586G1123 ENSG00000179632 MAF1 homolog, negative regulator of RNA polymerase III 8 144104499-144107611 Predicted intracellular proteins Evidence at protein level HPA024821, HPA058548 Uncertain Supported Nucleus
Nucleoli
Vesicles Liver cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 142.6 MAFG MGC13090, MGC20149 ENSG00000197063 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 17 81918270-81927714 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025573 Approved Liver cancer:1.90e-6 (unfavourable), Endometrial cancer:5.82e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 28.3 MAFK NFE2U, P18 ENSG00000198517 V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 7 1530714-1543043 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026820, HPA060841 Approved Validated Nucleoplasm Expressed in all Expressed in all placenta: 36.6 MAGED1 DLXIN-1, NRAGE ENSG00000179222 Melanoma antigen family D1 X 51803007-51902357 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043645 Approved Cytosol Thyroid cancer:3.25e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 194.4 MAGED2 11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386 ENSG00000102316 Melanoma antigen family D2 X 54807599-54816012 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031572, HPA031573 Supported Validated Nucleus
Nucleoli
Cytosol Pancreatic cancer:2.82e-4 (favourable), Ovarian cancer:2.88e-4 (favourable), Stomach cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all prostate: 313.4 MAGEF1 ENSG00000177383 Melanoma antigen family F1 3 184710367-184712002 Predicted intracellular proteins Evidence at protein level HPA046899, HPA054190 Uncertain Approved Actin filaments Renal cancer:7.59e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 60.2 MAGOH MAGOH1, MAGOHA ENSG00000162385 Mago homolog, exon junction complex core component 1 53226892-53238610 Predicted intracellular proteins, Transporters Evidence at protein level CAB015425, HPA043036, HPA047754 Approved Supported Nucleus Renal cancer:1.45e-5 (unfavourable), Breast cancer:1.85e-4 (favourable) Expressed in all Expressed in all lymph node: 83.5 MAGT1 DKFZp564K142, IAP, MRX95, OST3B ENSG00000102158 Magnesium transporter 1 X 77826364-77895593 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA049851 Approved Breast cancer:1.30e-4 (unfavourable), Pancreatic cancer:3.55e-4 (unfavourable), Melanoma:8.98e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 136.9 MAK16 MAK16L, RBM13 ENSG00000198042 MAK16 homolog 8 33484750-33501260 Predicted intracellular proteins Evidence at protein level HPA044417, HPA050574 Uncertain Supported Nucleoli
Vesicles Liver cancer:1.00e-4 (unfavourable), Renal cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 12.6 MALT1 MLT, PCASP1 ENSG00000172175 MALT1 paracaspase 18 58671386-58754477 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004494, HPA048432 Supported Supported Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 34.4 MAML1 KIAA0200, Mam-1 ENSG00000161021 Mastermind-like transcriptional coactivator 1 5 179732850-179796511 Predicted intracellular proteins Evidence at protein level HPA037687, HPA057531 Approved Validated Nucleoplasm Renal cancer:1.84e-5 (unfavourable), Melanoma:9.70e-4 (unfavourable) Expressed in all Expressed in all endometrium: 22.9 MAN1A1 ENSG00000111885 Mannosidase, alpha, class 1A, member 1 6 119177209-119349761 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB037058, HPA053198, HPA063561 Uncertain Supported Golgi apparatus
Cytosol Expressed in all Expressed in all placenta: 111.4 MAN1A2 MAN1B ENSG00000198162 Mannosidase, alpha, class 1A, member 2 1 117367449-117528872 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034559, HPA057364 Supported Validated Golgi apparatus Ovarian cancer:4.08e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 43.5 MAN1B1 MANA-ER, MRT15 ENSG00000177239 Mannosidase, alpha, class 1B, member 1 9 137086927-137109187 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051516 Approved Uncertain Vesicles Liver cancer:1.45e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 33.0 MAN2A1 GOLIM7, MANA2 ENSG00000112893 Mannosidase, alpha, class 2A, member 1 5 109689366-109869625 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB022377, HPA026896 Supported Supported Golgi apparatus Expressed in all Expressed in all parathyroid gland: 39.9 MAN2A2 HsT19662, MANA2X ENSG00000196547 Mannosidase, alpha, class 2A, member 2 15 90902218-90922584 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017226 Approved Renal cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 46.4 MAN2B1 LAMAN, MANB ENSG00000104774 Mannosidase, alpha, class 2B, member 1 19 12646511-12666742 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA041530, HPA053404 Supported Approved Nucleoplasm
Vesicles Renal cancer:1.94e-5 (unfavourable) Expressed in all Expressed in all spleen: 96.8 MAN2B2 KIAA0935 ENSG00000013288 Mannosidase, alpha, class 2B, member 2 4 6575175-6623362 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA037005 Uncertain Endometrial cancer:7.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 37.6 MAN2C1 MANA, MANA1 ENSG00000140400 Mannosidase, alpha, class 2C, member 1 15 75355207-75368630 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040627, HPA067407 Uncertain Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 46.6 MANBA ENSG00000109323 Mannosidase, beta A, lysosomal 4 102631488-102760994 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA053478 Approved Supported Vesicles Liver cancer:3.74e-6 (unfavourable), Glioma:1.06e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.8 MANBAL dJ1141E15.2 ENSG00000101363 Mannosidase, beta A, lysosomal-like 20 37289638-37317260 Predicted membrane proteins Evidence at protein level HPA052348 Approved Nucleus
Mitochondria Renal cancer:3.62e-4 (favourable), Liver cancer:7.07e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 95.1 MANF ARMET, ARP ENSG00000145050 Mesencephalic astrocyte-derived neurotrophic factor 3 51385047-51389397 Predicted secreted proteins Evidence at protein level HPA011175 Approved Supported Endoplasmic reticulum Head and neck cancer:9.58e-6 (unfavourable), Liver cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all epididymis: 123.2 MAP1LC3A ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3 ENSG00000101460 Microtubule-associated protein 1 light chain 3 alpha 20 34546854-34560345 Predicted intracellular proteins Evidence at protein level HPA007649, CAB037174, HPA043000, HPA052474, HPA052484 Supported Supported Microtubule organizing center Pancreatic cancer:5.31e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 119.4 MAP1LC3B ATG8F ENSG00000140941 Microtubule-associated protein 1 light chain 3 beta 16 87383995-87404779 Predicted intracellular proteins Evidence at protein level CAB037216, HPA043000, HPA052474, HPA052484, HPA053767 Uncertain Supported Microtubule organizing center Renal cancer:2.77e-7 (favourable), Stomach cancer:8.97e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 122.6 MAP1S BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1 ENSG00000130479 Microtubule-associated protein 1S 19 17719242-17734516 Predicted intracellular proteins Evidence at protein level HPA050934, HPA054637 Approved Validated Cytosol Pancreatic cancer:2.65e-4 (favourable), Liver cancer:5.29e-4 (unfavourable) Expressed in all Expressed in all testis: 29.6 MAP2K1 MAPKK1, MEK1, PRKMK1 ENSG00000169032 Mitogen-activated protein kinase kinase 1 15 66386817-66492312 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB003834, HPA026430 Approved Validated Plasma membrane
Cytosol Glioma:2.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.8 MAP2K2 MEK2, PRKMK2 ENSG00000126934 Mitogen-activated protein kinase kinase 2 19 4090321-4124129 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB003835, HPA051993 Supported Validated Cytosol Stomach cancer:5.43e-5 (favourable), Cervical cancer:3.72e-4 (favourable), Head and neck cancer:7.98e-4 (favourable) Expressed in all Expressed in all duodenum: 138.7 MAP2K3 MAPKK3, MEK3, MKK3, PRKMK3 ENSG00000034152 Mitogen-activated protein kinase kinase 3 17 21284672-21315240 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB018548 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all bone marrow: 130.3 MAP2K4 JNKK1, MEK4, MKK4, PRKMK4, SERK1 ENSG00000065559 Mitogen-activated protein kinase kinase 4 17 12020824-12143830 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007751, HPA060074 Supported Approved Nucleoplasm
Cell Junctions Expressed in all Expressed in all cerebral cortex: 64.2 MAP2K5 HsT17454, MAPKK5, MEK5, PRKMK5 ENSG00000137764 Mitogen-activated protein kinase kinase 5 15 67542709-67807123 Enzymes, Predicted intracellular proteins Evidence at protein level CAB022094, HPA027347, HPA027755 Supported Approved Nucleoli
Microtubules Renal cancer:8.03e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 32.1 MAP2K7 Jnkk2, MKK7, PRKMK7 ENSG00000076984 Mitogen-activated protein kinase kinase 7 19 7903843-7914478 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001633, CAB004262, HPA064711 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Head and neck cancer:8.54e-5 (favourable), Urothelial cancer:1.56e-4 (favourable) Expressed in all Expressed in all spleen: 19.5 MAP3K11 MEKK11, MLK3, PTK1, SPRK ENSG00000173327 Mitogen-activated protein kinase kinase kinase 11 11 65597755-65615382 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010165 Approved Supported Microtubule organizing center
Cytosol Expressed in all Expressed in all spleen: 56.0 MAP3K13 LZK, MEKK13 ENSG00000073803 Mitogen-activated protein kinase kinase kinase 13 3 185282941-185489097 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA016497, HPA036691, HPA036692 Uncertain Approved Nucleoplasm
Microtubule organizing center
Cytosol Endometrial cancer:1.28e-5 (unfavourable), Pancreatic cancer:7.27e-5 (unfavourable), Ovarian cancer:1.11e-4 (favourable) Expressed in all Expressed in all epididymis: 68.4 MAP3K14 FTDCR1B, HS, HSNIK, NIK ENSG00000006062 Mitogen-activated protein kinase kinase kinase 14 17 45263121-45317040 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027270 Supported Nucleus
Nucleoli fibrillar center
Vesicles
Cytosol Cervical cancer:5.27e-5 (favourable), Renal cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all lymph node: 23.2 MAP3K2 MEKK2, MEKK2B ENSG00000169967 Mitogen-activated protein kinase kinase kinase 2 2 127298730-127388465 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021540 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 29.7 MAP3K3 MAPKKK3, MEKK3 ENSG00000198909 Mitogen-activated protein kinase kinase kinase 3 17 63622415-63696303 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007764, HPA035410, HPA035411 Uncertain Approved Nucleoplasm Endometrial cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 42.3 MAP3K4 KIAA0213, MAPKKK4, MEKK4, MTK1 ENSG00000085511 Mitogen-activated protein kinase kinase kinase 4 6 160991727-161117385 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA007625 Uncertain Approved Cytosol Expressed in all Expressed in all endometrium: 15.3 MAP3K5 ASK1, MAPKKK5, MEKK5 ENSG00000197442 Mitogen-activated protein kinase kinase kinase 5 6 136557047-136792518 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB007824, HPA063245, HPA064423 Approved Supported Cytosol Pancreatic cancer:5.91e-4 (unfavourable), Head and neck cancer:6.08e-4 (favourable) Expressed in all Expressed in all adrenal gland: 116.3 MAP3K7 MEKK7, TAK1 ENSG00000135341 Mitogen-activated protein kinase kinase kinase 7 6 90513573-90587045 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007633 Approved Approved Nuclear speckles
Cytosol Liver cancer:3.51e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.6 MAP3K8 c-COT, COT, EST, ESTF, MEKK8, Tpl-2 ENSG00000107968 Mitogen-activated protein kinase kinase kinase 8 10 30433937-30461833 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005120, HPA017962 Supported Supported Cytosol Renal cancer:8.76e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 210.1 MAP4 ENSG00000047849 Microtubule-associated protein 4 3 47850690-48089272 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038149, HPA038150 Supported Supported Plasma membrane
Microtubules
Cytosol Liver cancer:1.82e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 242.6 MAP4K3 GLK, MAPKKKK3, RAB8IPL1 ENSG00000011566 Mitogen-activated protein kinase kinase kinase kinase 3 2 39249266-39437312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030380 Approved Approved Centrosome Expressed in all Expressed in all thyroid gland: 40.7 MAP4K4 FLH21957, HGK, NIK ENSG00000071054 Mitogen-activated protein kinase kinase kinase kinase 4 2 101696850-101894689 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008476 Uncertain Renal cancer:3.62e-6 (unfavourable), Lung cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 155.0 MAP4K5 GCKR, KHS, KHS1 ENSG00000012983 Mitogen-activated protein kinase kinase kinase kinase 5 14 50418501-50561126 Predicted intracellular proteins Evidence at protein level HPA036696 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all endometrium: 54.9 MAP7D1 FLJ10350, FLJ39022, PARCC1, RPRC1 ENSG00000116871 MAP7 domain containing 1 1 36155579-36180849 Predicted intracellular proteins Evidence at protein level HPA028075 Approved Approved Microtubules
Cytosol Liver cancer:1.49e-6 (unfavourable), Renal cancer:8.56e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 117.0 MAPK1 ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2 ENSG00000100030 Mitogen-activated protein kinase 1 22 21754500-21867680 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003995, CAB004229, HPA005700, HPA030069 Approved Liver cancer:4.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 132.8 MAPK14 CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15 ENSG00000112062 Mitogen-activated protein kinase 14 6 36027677-36111236 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB010285, CAB040578, HPA051825 Approved Supported Nuclear speckles Expressed in all Expressed in all placenta: 62.7 MAPK1IP1L C14orf32 ENSG00000168175 Mitogen-activated protein kinase 1 interacting protein 1-like 14 55051631-55070192 Predicted intracellular proteins Evidence at protein level HPA034506 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:4.82e-5 (favourable) Expressed in all Expressed in all bone marrow: 53.3 MAPK3 ERK1, p44erk1, p44mapk, PRKM3 ENSG00000102882 Mitogen-activated protein kinase 3 16 30114105-30123506 Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB002683, HPA003995, HPA005700, HPA030069 Approved Approved Nucleoplasm Liver cancer:1.11e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 134.1 MAPK6 ERK3, HsT17250, p97MAPK, PRKM6 ENSG00000069956 Mitogen-activated protein kinase 6 15 51952106-52067372 Enzymes, Predicted intracellular proteins Evidence at protein level CAB005184, HPA030262 Approved Validated Cytosol Expressed in all Expressed in all testis: 52.7 MAPK8 JNK, JNK1, PRKM8, SAPK1 ENSG00000107643 Mitogen-activated protein kinase 8 10 48306639-48439360 Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004463, CAB069396 Approved Liver cancer:8.66e-4 (unfavourable), Renal cancer:8.66e-4 (favourable) Expressed in all Expressed in all testis: 34.9 MAPK8IP3 JIP3, JSAP1, KIAA1066, syd ENSG00000138834 Mitogen-activated protein kinase 8 interacting protein 3 16 1706183-1770317 Predicted intracellular proteins Evidence at protein level CAB005580, HPA041785, HPA069311 Approved Approved Vesicles Renal cancer:5.25e-5 (unfavourable), Urothelial cancer:3.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 84.1 MAPK9 JNK2, p54a, PRKM9, SAPK ENSG00000050748 Mitogen-activated protein kinase 9 5 180233143-180292099 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB008910 Approved Colorectal cancer:1.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 84.1 MAPKAP1 MGC2745, MIP1, SIN1 ENSG00000119487 Mitogen-activated protein kinase associated protein 1 9 125437393-125707234 Predicted intracellular proteins Evidence at protein level HPA029091, HPA029092 Supported Supported Nucleoplasm
Cytosol Renal cancer:7.23e-6 (favourable) Expressed in all Expressed in all thyroid gland: 79.4 MAPKAPK2 ENSG00000162889 Mitogen-activated protein kinase-activated protein kinase 2 1 206684944-206734283 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level CAB010297, HPA045556, HPA063708, HPA064435 Approved Supported Nucleoplasm
Centrosome Renal cancer:4.58e-6 (unfavourable), Liver cancer:1.93e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 113.2 MAPKAPK3 3pK, MAPKAP3 ENSG00000114738 Mitogen-activated protein kinase-activated protein kinase 3 3 50611520-50649297 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058275 Supported Nucleoplasm Renal cancer:1.90e-8 (favourable), Colorectal cancer:8.08e-5 (favourable) Expressed in all Expressed in all heart muscle: 117.7 MAPKAPK5 PRAK ENSG00000089022 Mitogen-activated protein kinase-activated protein kinase 5 12 111841978-111902238 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004546, HPA015515 Supported Supported Nucleoplasm
Cytosol Liver cancer:2.98e-8 (unfavourable) Expressed in all Expressed in all rectum: 34.4 MAPRE1 EB1 ENSG00000101367 Microtubule-associated protein, RP/EB family, member 1 20 32819893-32850405 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003600, CAB009337, CAB019391 Supported Validated Microtubule organizing center
Cytosol Liver cancer:6.33e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 126.8 MAPRE2 EB1, EB2, RP1 ENSG00000166974 Microtubule-associated protein, RP/EB family, member 2 18 34976928-35143470 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016738, HPA016739 Supported Uncertain Nucleoplasm Expressed in all Expressed in all cerebral cortex: 175.1 MARC1 FLJ22390, MOSC1 ENSG00000186205 Mitochondrial amidoxime reducing component 1 1 220786759-220819657 Predicted intracellular proteins Evidence at protein level HPA028702 Approved Supported Mitochondria Renal cancer:4.51e-4 (unfavourable) Mixed Expressed in all adipose tissue: 225.6 MARCH2 HSPC240, MARCH-II, RNF172 ENSG00000099785 Membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase 19 8413270-8439017 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014063 Approved Uncertain Cytosol Endometrial cancer:1.05e-5 (favourable), Pancreatic cancer:6.21e-4 (favourable), Colorectal cancer:6.48e-4 (unfavourable), Head and neck cancer:8.29e-4 (favourable) Expressed in all Expressed in all epididymis: 63.9 MARCH5 FLJ20445, MARCH-V, RNF153 ENSG00000198060 Membrane-associated ring finger (C3HC4) 5 10 92291163-92353964 Predicted membrane proteins Evidence at protein level HPA056596 Supported Mitochondria Expressed in all Expressed in all thyroid gland: 28.6 MARCH6 MARCH-VI, RNF176, TEB4 ENSG00000145495 Membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 5 10353703-10440388 Predicted membrane proteins Evidence at protein level HPA040841, HPA063246 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 95.0 MARCH7 AXOT, MARCH-VII, RNF177 ENSG00000136536 Membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 2 159712457-159771027 Predicted intracellular proteins Evidence at protein level HPA014275, HPA022152 Approved Supported Plasma membrane
Cytosol Renal cancer:1.84e-4 (unfavourable), Liver cancer:2.41e-4 (unfavourable) Expressed in all Expressed in all testis: 111.7 MARCH8 c-MIR, CMIR, MARCH-VIII, MIR, RNF178 ENSG00000165406 Membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 10 45454585-45594906 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014597 Approved Pancreatic cancer:2.71e-4 (favourable), Renal cancer:6.64e-4 (favourable) Expressed in all Expressed in all testis: 104.3 MARCH9 FLJ36578, RNF179 ENSG00000139266 Membrane-associated ring finger (C3HC4) 9 12 57755098-57760407 Predicted membrane proteins Evidence at protein level Lung cancer:1.54e-5 (favourable), Renal cancer:2.98e-5 (favourable), Ovarian cancer:1.59e-4 (favourable), Endometrial cancer:3.07e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 29.7 MARCKS 80K-L, MACS, PKCSL ENSG00000277443 Myristoylated alanine-rich protein kinase C substrate 6 113857362-113863471 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022062, HPA051913, HPA054820 Uncertain Approved Nucleoli
Plasma membrane
Cytosol Liver cancer:2.78e-8 (unfavourable), Renal cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 219.4 MARCKSL1 F52, MacMARCKS, MLP, MLP1 ENSG00000175130 MARCKS-like 1 1 32333832-32336379 Predicted intracellular proteins Evidence at protein level CAB020787, HPA030528 Approved Supported Nucleoplasm
Actin filaments
Cytosol Liver cancer:1.78e-6 (unfavourable), Renal cancer:1.20e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 316.0 MARK2 EMK1, PAR-1, PAR-1B, Par1b ENSG00000072518 MAP/microtubule affinity-regulating kinase 2 11 63838928-63911019 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038790, HPA074905 Approved Supported Nucleoplasm
Plasma membrane Liver cancer:1.30e-4 (unfavourable), Endometrial cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all skin: 46.2 MARK3 CTAK1, KP78, PAR-1A ENSG00000075413 MAP/microtubule affinity-regulating kinase 3 14 103385392-103503831 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024652 Approved Approved Nuclear membrane Melanoma:1.14e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 64.1 MARK4 FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D ENSG00000007047 MAP/microtubule affinity-regulating kinase 4 19 45079288-45305283 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039186 Approved Approved Cytosol Endometrial cancer:8.31e-8 (unfavourable), Head and neck cancer:3.05e-5 (unfavourable) Expressed in all Expressed in all testis: 51.2 MARS CMT2U, MetRS, SPG70 ENSG00000166986 Methionyl-tRNA synthetase 12 57475445-57517569 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004125, CAB017097 Supported Approved Validated Cytosol Liver cancer:4.55e-7 (unfavourable), Renal cancer:1.59e-4 (unfavourable), Breast cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all testis: 66.4 MARS2 mtMetRS, SPAX3 ENSG00000247626 Methionyl-tRNA synthetase 2, mitochondrial 2 197705369-197708387 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035589, HPA035590 Uncertain Approved Intermediate filaments
Cytosol Renal cancer:6.14e-5 (favourable), Glioma:1.49e-4 (favourable), Endometrial cancer:3.50e-4 (unfavourable) Expressed in all Expressed in all lymph node: 7.6 MAST2 KIAA0807, MAST205 ENSG00000086015 Microtubule associated serine/threonine kinase 2 1 45786987-46036124 Cancer-related genes, Enzymes, Predicted membrane proteins Evidence at protein level HPA039722, HPA040155 Approved Approved Cytosol Renal cancer:6.85e-13 (unfavourable), Liver cancer:4.31e-8 (unfavourable) Expressed in all Expressed in all testis: 78.5 MAST3 KIAA0561 ENSG00000099308 Microtubule associated serine/threonine kinase 3 19 18097793-18151692 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035061, HPA035062 Uncertain Approved Nuclear speckles Head and neck cancer:2.97e-4 (favourable), Pancreatic cancer:7.01e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 51.6 MAT2A MATA2, MATII, SAMS2 ENSG00000168906 Methionine adenosyltransferase II, alpha 2 85539165-85545280 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009968, HPA043028 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:5.29e-5 (unfavourable), Melanoma:5.94e-5 (unfavourable), Liver cancer:4.87e-4 (unfavourable), Lung cancer:8.94e-4 (favourable) Expressed in all Expressed in all thyroid gland: 643.6 MAT2B MATIIbeta, SDR23E1 ENSG00000038274 Methionine adenosyltransferase II, beta 5 163503114-163519336 Predicted intracellular proteins Evidence at protein level HPA037721, HPA037722 Uncertain Renal cancer:4.51e-7 (favourable) Expressed in all Expressed in all thyroid gland: 132.8 MATN2 ENSG00000132561 Matrilin 2 8 97868840-98036716 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033879 Approved Thyroid cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 454.2 MATR3 KIAA0723, MGC9105, MPD2, VCPDM ENSG00000015479 Matrin 3 5 139293648-139331359 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033552, HPA036564, HPA036565 Supported Approved Nucleoplasm Mixed Expressed in all cerebral cortex: 334.1 MATR3 ENSG00000280987 Matrin 3 5 139273752-139331677 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036564, HPA036565 Supported Approved Nucleoplasm Not detected Expressed in all cerebral cortex: 63.1 MAU2 KIAA0892, mau-2, MAU2L, MGC75361, SCC4 ENSG00000129933 MAU2 sister chromatid cohesion factor 19 19320681-19358755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059897 Supported Nucleoplasm Head and neck cancer:3.90e-5 (favourable) Expressed in all Expressed in all testis: 25.6 MAVS Cardif, IPS-1, KIAA1271, VISA ENSG00000088888 Mitochondrial antiviral signaling protein 20 3846799-3876123 Predicted membrane proteins Evidence at protein level CAB009187, HPA049850, HPA053524 Supported Validated Mitochondria Renal cancer:4.13e-5 (favourable), Pancreatic cancer:3.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.4 MAX bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8 ENSG00000125952 MYC associated factor X 14 65006174-65102695 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000328, HPA003474 Supported Supported Nucleoplasm
Golgi apparatus
Vesicles Thyroid cancer:2.12e-4 (favourable), Renal cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 80.2 MAZ Pur-1, ZF87, Zif87, ZNF801 ENSG00000103495 MYC-associated zinc finger protein (purine-binding transcription factor) 16 29806106-29811164 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA048315, HPA059495, HPA065930 Approved Supported Nucleus Thyroid cancer:2.22e-4 (unfavourable), Renal cancer:5.15e-4 (unfavourable) Expressed in all Expressed in all prostate: 195.5 MBD1 CXXC3, PCM1 ENSG00000141644 Methyl-CpG binding domain protein 1 18 50266882-50281774 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009017, CAB036003 Approved Supported Nucleus Prostate cancer:1.70e-6 (unfavourable), Liver cancer:5.08e-6 (unfavourable) Expressed in all Expressed in all testis: 109.0 MBD2 ENSG00000134046 Methyl-CpG binding domain protein 2 18 54151601-54224788 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB037282, HPA067582, HPA067615 Approved Validated Nucleoplasm Colorectal cancer:6.49e-4 (favourable) Expressed in all Expressed in all thyroid gland: 50.3 MBD3 ENSG00000071655 Methyl-CpG binding domain protein 3 19 1573596-1592801 Predicted intracellular proteins Evidence at protein level CAB013265 Supported Supported Nucleoplasm Pancreatic cancer:1.76e-5 (favourable), Liver cancer:2.99e-4 (unfavourable), Endometrial cancer:5.08e-4 (favourable) Expressed in all Expressed in all placenta: 45.7 MBD4 MED1 ENSG00000129071 Methyl-CpG binding domain 4 DNA glycosylase 3 129430944-129440179 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA002031 Supported Supported Nuclear speckles Renal cancer:2.73e-6 (unfavourable), Pancreatic cancer:2.18e-4 (unfavourable), Prostate cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all lymph node: 77.5 MBD6 KIAA1887 ENSG00000166987 Methyl-CpG binding domain protein 6 12 57520710-57530148 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038948, HPA038949 Uncertain Validated Nucleus Expressed in all Expressed in all testis: 66.5 MBIP ENSG00000151332 MAP3K12 binding inhibitory protein 1 14 36298558-36320676 Predicted intracellular proteins Evidence at protein level HPA003388 Supported Supported Nucleus
Nucleoli
Cytosol Ovarian cancer:1.14e-4 (favourable), Renal cancer:1.25e-4 (favourable), Lung cancer:1.52e-4 (favourable) Expressed in all Expressed in all thyroid gland: 135.8 MBNL1 EXP, EXP35, EXP40, EXP42, KIAA0428, MBNL ENSG00000152601 Muscleblind-like splicing regulator 1 3 152243828-152465780 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB016398, HPA035098, HPA062046 Supported Supported Nucleoplasm
Cytosol Renal cancer:2.90e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 179.7 MBNL2 MBLL, MBLL39 ENSG00000139793 Muscleblind-like splicing regulator 2 13 97221434-97394120 Predicted intracellular proteins Evidence at protein level HPA062685 Supported Nucleoplasm Pancreatic cancer:1.99e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 84.5 MBOAT7 BB1, hMBOA-7, LENG4, LPIAT ENSG00000125505 Membrane bound O-acyltransferase domain containing 7 19 54173412-54189882 Enzymes, Predicted membrane proteins Evidence at protein level HPA055967 Approved Approved Cytosol Liver cancer:5.55e-6 (unfavourable), Renal cancer:6.62e-5 (unfavourable), Urothelial cancer:4.31e-4 (favourable), Lung cancer:5.13e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 24.3 MBTD1 FLJ20055, SA49P01 ENSG00000011258 Mbt domain containing 1 17 51177425-51260163 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021876 Approved Approved Nucleus
Cytosol Expressed in all Expressed in all testis: 45.9 MBTPS1 KIAA0091, PCSK8, S1P, SKI-1 ENSG00000140943 Membrane-bound transcription factor peptidase, site 1 16 84053761-84116906 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA056109 Supported Renal cancer:2.21e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 116.3 MBTPS2 KFSD, S2P ENSG00000012174 Membrane-bound transcription factor peptidase, site 2 X 21839636-21885424 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA005494, CAB009486 Approved Approved Nucleoplasm
Mitochondria
Cytosol Expressed in all Expressed in all parathyroid gland: 19.0 MCAT fabD, FASN2C, MCT, MT, NET62 ENSG00000100294 Malonyl CoA:ACP acyltransferase (mitochondrial) 22 43132206-43143394 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003122, HPA035471 Approved Supported Mitochondria Renal cancer:2.18e-4 (favourable), Stomach cancer:3.89e-4 (favourable), Endometrial cancer:5.53e-4 (favourable) Expressed in all Expressed in all fallopian tube: 22.7 MCCC1 MCCA ENSG00000078070 Methylcrotonoyl-CoA carboxylase 1 (alpha) 3 183015218-183116075 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008310 Approved Validated Mitochondria Renal cancer:3.68e-4 (favourable) Expressed in all Expressed in all kidney: 60.7 MCCC2 MCCB ENSG00000131844 Methylcrotonoyl-CoA carboxylase 2 (beta) 5 71587288-71658704 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038300, HPA038301, HPA061546 Supported Validated Mitochondria Renal cancer:6.43e-8 (favourable), Liver cancer:1.70e-4 (favourable), Colorectal cancer:3.62e-4 (favourable) Expressed in all Expressed in all prostate: 75.0 MCEE GLOD2 ENSG00000124370 Methylmalonyl CoA epimerase 2 71109684-71130239 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035196 Approved Nucleoli Head and neck cancer:4.76e-4 (favourable), Liver cancer:5.78e-4 (favourable) Expressed in all Expressed in all breast: 40.7 MCFD2 F5F8D, LMAN1IP, SDNSF ENSG00000180398 Multiple coagulation factor deficiency 2 2 46901870-46941855 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022410, HPA034593 Supported Urothelial cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 207.9 MCL1 BCL2L3, Mcl-1 ENSG00000143384 Myeloid cell leukemia 1 1 150574551-150579738 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002781, HPA008455, HPA031125, CAB068195 Approved Validated Mitochondria Renal cancer:7.16e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 662.8 MCM3 ENSG00000112118 Minichromosome maintenance complex component 3 6 52264009-52284881 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002162, HPA004789, HPA004790 Supported Validated Nucleoplasm Thyroid cancer:3.13e-5 (favourable), Melanoma:4.40e-5 (unfavourable), Liver cancer:1.40e-4 (unfavourable), Cervical cancer:1.89e-4 (favourable) Expressed in all Expressed in all lymph node: 81.8 MCM3AP GANP, KIAA0572, Map80, SAC3 ENSG00000160294 Minichromosome maintenance complex component 3 associated protein 21 46235126-46286297 Predicted intracellular proteins, Transporters Evidence at protein level HPA021527, HPA032103 Approved Supported Nucleus
Nuclear membrane
Cytosol Pancreatic cancer:2.05e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 35.1 MCM4 CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21 ENSG00000104738 Minichromosome maintenance complex component 4 8 47960185-47978160 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004497, HPA004873, HPA031052 Supported Validated Nucleoplasm Endometrial cancer:2.84e-5 (unfavourable), Melanoma:1.15e-4 (unfavourable), Liver cancer:1.23e-4 (unfavourable), Colorectal cancer:2.19e-4 (favourable), Pancreatic cancer:2.38e-4 (unfavourable), Renal cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all testis: 78.4 MCM5 CDC46 ENSG00000100297 Minichromosome maintenance complex component 5 22 35400063-35425430 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000101, HPA000845, HPA052880 Supported Validated Nucleoplasm Cervical cancer:2.81e-6 (favourable), Renal cancer:3.58e-5 (unfavourable), Liver cancer:1.78e-4 (unfavourable), Lung cancer:3.95e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 88.7 MCM7 CDC47, MCM2, PPP1R104 ENSG00000166508 Minichromosome maintenance complex component 7 7 100092728-100101940 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002163, HPA003898, CAB016312 Supported Validated Nucleoplasm Cervical cancer:1.28e-4 (favourable), Liver cancer:2.18e-4 (unfavourable) Expressed in all Expressed in all lymph node: 41.9 MCMBP C10orf119, FLJ13081, MCM-BP ENSG00000197771 Minichromosome maintenance complex binding protein 10 119829404-119892556 Predicted intracellular proteins Evidence at protein level CAB013792, HPA038481 Uncertain Validated Nucleoplasm Pancreatic cancer:2.20e-4 (unfavourable), Renal cancer:6.18e-4 (unfavourable) Expressed in all Expressed in all placenta: 63.1 MCOLN1 ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1 ENSG00000090674 Mucolipin 1 19 7522626-7534009 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA031763, CAB032637 Uncertain Supported Plasma membrane
Cytosol Pancreatic cancer:5.60e-5 (favourable), Renal cancer:5.67e-4 (favourable) Expressed in all Expressed in all spleen: 49.0 MCPH1 BRIT1, FLJ12847 ENSG00000147316 Microcephalin 1 8 6406592-6648504 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008238, CAB012177 Supported Uncertain Nucleoplasm
Nuclear bodies Colorectal cancer:8.52e-4 (favourable) Expressed in all Expressed in all testis: 19.4 MCRS1 ICP22BP, INO80Q, MCRS2, MSP58, P78 ENSG00000187778 Microspherule protein 1 12 49556544-49568153 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039057 Supported Supported Nucleoplasm Liver cancer:2.30e-4 (unfavourable), Renal cancer:2.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 54.9 MCTS1 MCT-1 ENSG00000232119 Malignant T cell amplified sequence 1 X 120594010-120621074 Predicted intracellular proteins Evidence at protein level HPA001045 Supported Plasma membrane
Cytosol Head and neck cancer:3.27e-5 (unfavourable), Renal cancer:4.35e-5 (unfavourable), Breast cancer:1.38e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.5 MCU C10orf42, CCDC109A, FLJ46135 ENSG00000156026 Mitochondrial calcium uniporter 10 72692131-72887694 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016480 Approved Supported Mitochondria Liver cancer:6.06e-5 (unfavourable), Renal cancer:5.07e-4 (favourable) Expressed in all Expressed in all stomach: 41.1 MCUR1 C6orf79, CCDC90A, FLJ20958 ENSG00000050393 Mitochondrial calcium uniporter regulator 1 6 13786557-13814568 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:3.32e-4 (favourable), Ovarian cancer:5.51e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.8 MDFIC HIC ENSG00000135272 MyoD family inhibitor domain containing 7 114922154-115019916 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA030716 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 47.6 MDH1 ENSG00000014641 Malate dehydrogenase 1, NAD (soluble) 2 63588609-63607197 Cancer-related genes, Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027296, CAB047333, HPA054276 Uncertain Supported Centrosome
Cytosol Endometrial cancer:7.13e-4 (unfavourable), Renal cancer:9.95e-4 (favourable) Expressed in all Expressed in all heart muscle: 736.3 MDH2 ENSG00000146701 Malate dehydrogenase 2, NAD (mitochondrial) 7 76048051-76067508 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019714, HPA019716, HPA019848, HPA026720 Supported Validated Mitochondria Renal cancer:1.49e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 233.3 MDK FLJ27379, MK, NEGF2 ENSG00000110492 Midkine (neurite growth-promoting factor 2) 11 46380756-46383837 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB010055, HPA057126 Uncertain Approved Vesicles Renal cancer:3.06e-6 (unfavourable), Glioma:9.54e-4 (unfavourable) Expressed in all Expressed in all ovary: 524.0 MDM1 ENSG00000111554 Mdm1 nuclear protein 12 68272443-68332381 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040411, HPA041594 Uncertain Supported Centrosome
Cytosol Cervical cancer:6.01e-4 (favourable) Expressed in all Expressed in all testis: 37.3 MDM2 HDM2, MGC5370 ENSG00000135679 MDM2 proto-oncogene, E3 ubiquitin protein ligase 12 68808172-68850686 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB000086, CAB016303 Supported Supported Nucleus Endometrial cancer:4.51e-7 (favourable), Cervical cancer:3.23e-4 (favourable) Expressed in all Expressed in all rectum: 44.3 MDM4 HDMX, MDMX ENSG00000198625 MDM4, p53 regulator 1 204516379-204558120 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA018919, HPA048821 Approved Supported Nucleus Renal cancer:7.06e-6 (unfavourable), Urothelial cancer:2.49e-4 (favourable), Prostate cancer:9.87e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 37.5 MDP1 FN6Pase, MGC5987 ENSG00000213920 Magnesium-dependent phosphatase 1 14 24213937-24216070 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003064, HPA070338 Uncertain Approved Nucleoplasm Renal cancer:5.96e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.2 ME2 ENSG00000082212 Malic enzyme 2, NAD(+)-dependent, mitochondrial 18 50879049-50954257 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008247, HPA008880 Supported Validated Mitochondria Liver cancer:8.29e-8 (unfavourable) Expressed in all Expressed in all spleen: 54.3 ME3 ENSG00000151376 Malic enzyme 3, NADP(+)-dependent, mitochondrial 11 86441108-86672636 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038473 Approved Urothelial cancer:3.86e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.0 MEA1 MEA ENSG00000124733 Male-enhanced antigen 1 6 43012094-43013968 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017921 Approved Approved Nucleus
Cytosol Renal cancer:1.29e-6 (unfavourable), Ovarian cancer:3.37e-4 (favourable) Expressed in all Expressed in all testis: 245.3 MEAF6 C1orf149, CENP-28, Eaf6, FLJ11730, NY-SAR-91 ENSG00000163875 MYST/Esa1-associated factor 6 1 37492575-37514774 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029599 Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all prostate: 145.0 MECP2 MRX16, MRX79, RTT ENSG00000169057 Methyl CpG binding protein 2 X 154021573-154137103 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000593, HPA001341, CAB037264 Supported Supported Nucleus Renal cancer:7.32e-9 (favourable), Endometrial cancer:8.35e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.4 MECR CGI-63, FASN2B, NRBF1 ENSG00000116353 Mitochondrial trans-2-enoyl-CoA reductase 1 29192873-29230942 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022018, HPA022030, HPA028740 Supported Supported Mitochondria Renal cancer:5.81e-6 (favourable), Urothelial cancer:5.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 18.4 MED1 CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2 ENSG00000125686 Mediator complex subunit 1 17 39404285-39451286 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017696, HPA052818 Approved Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 56.9 MED10 L6, MGC5309, NUT2, TRG20 ENSG00000133398 Mediator complex subunit 10 5 6371881-6378594 Predicted intracellular proteins Evidence at protein level HPA042795, HPA054188 Supported Nucleoplasm Liver cancer:1.62e-6 (unfavourable), Renal cancer:2.19e-5 (unfavourable), Glioma:4.81e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 44.9 MED11 HSPC296, MGC88387 ENSG00000161920 Mediator complex subunit 11 17 4731428-4733610 Predicted intracellular proteins Evidence at protein level HPA056669 Uncertain Approved Nucleoplasm
Nuclear bodies Endometrial cancer:1.86e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 49.1 MED12 CAGH45, FGS1, HOPA, KIAA0192, OKS, OPA1, TNRC11, TRAP230 ENSG00000184634 Mediator complex subunit 12 X 71118556-71142454 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003184, HPA003185 Supported Approved Nucleoplasm Expressed in all Expressed in all spleen: 27.1 MED13 KIAA0593, THRAP1, TRAP240 ENSG00000108510 Mediator complex subunit 13 17 61942605-62065282 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA067939 Supported Nucleus Colorectal cancer:1.43e-4 (favourable) Expressed in all Expressed in all testis: 35.5 MED13L KIAA1025, THRAP2, TRAP240L ENSG00000123066 Mediator complex subunit 13-like 12 115953872-116277338 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039445 Uncertain Approved Nucleus
Golgi apparatus Expressed in all Expressed in all bone marrow: 36.0 MED14 CRSP150, CRSP2, CSRP, CXorf4, EXLM1, RGR1, TRAP170 ENSG00000180182 Mediator complex subunit 14 X 40648306-40735858 Predicted intracellular proteins Evidence at protein level HPA064182 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 31.6 MED15 Arc105, CAG7A, PCQAP, TIG-1, TNRC7 ENSG00000099917 Mediator complex subunit 15 22 20495913-20587632 Predicted intracellular proteins Evidence at protein level HPA003179 Approved Supported Nucleus Endometrial cancer:7.30e-5 (favourable), Renal cancer:1.61e-4 (unfavourable), Liver cancer:3.71e-4 (unfavourable), Pancreatic cancer:9.09e-4 (unfavourable) Expressed in all Expressed in all spleen: 44.4 MED16 DRIP92, THRAP5, TRAP95 ENSG00000175221 Mediator complex subunit 16 19 867630-893218 Predicted intracellular proteins Evidence at protein level HPA030685, HPA046495 Uncertain Approved Nucleoli Renal cancer:1.11e-5 (favourable), Endometrial cancer:5.46e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.0 MED17 CRSP6, CRSP77, DRIP80, TRAP80 ENSG00000042429 Mediator complex subunit 17 11 93784227-93814695 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064236 Approved Vesicles Liver cancer:4.04e-6 (unfavourable), Breast cancer:4.94e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 26.5 MED18 FLJ20045, p28b ENSG00000130772 Mediator complex subunit 18 1 28329002-28335967 Predicted intracellular proteins Evidence at protein level HPA027429 Uncertain Approved Nucleoplasm Renal cancer:8.38e-5 (favourable), Liver cancer:1.52e-4 (unfavourable), Endometrial cancer:3.93e-4 (favourable), Stomach cancer:6.72e-4 (favourable) Expressed in all Expressed in all fallopian tube,lymph node: 13.0 MED19 LCMR1 ENSG00000156603 Mediator complex subunit 19 11 57703714-57712221 Predicted intracellular proteins Evidence at protein level HPA039912, HPA040860 Uncertain Supported Nucleus
Nuclear bodies Liver cancer:1.34e-6 (unfavourable), Ovarian cancer:1.76e-6 (favourable) Expressed in all Expressed in all testis: 30.8 MED20 DKFZp586D2223, PRO0213, TRFP ENSG00000124641 Mediator complex subunit 20 6 41905354-41921139 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040717 Uncertain Approved Nucleoplasm
Centrosome Melanoma:1.48e-5 (unfavourable), Renal cancer:1.17e-4 (favourable) Expressed in all Expressed in all placenta,thyroid gland: 20.7 MED21 SRB7, SURB7 ENSG00000152944 Mediator complex subunit 21 12 27022546-27066343 Predicted intracellular proteins Evidence at protein level HPA017177 Uncertain Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.74e-8 (favourable) Expressed in all Expressed in all testis: 69.0 MED22 Med24, SURF5 ENSG00000148297 Mediator complex subunit 22 9 133338323-133348131 Predicted intracellular proteins Evidence at protein level HPA020391, HPA063694 Uncertain Approved Nucleoplasm Renal cancer:3.76e-11 (favourable), Liver cancer:5.16e-6 (unfavourable), Pancreatic cancer:6.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 10.7 MED23 CRSP130, CRSP3, DRIP130, Sur2 ENSG00000112282 Mediator complex subunit 23 6 131573966-131628229 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA070341 Approved Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 31.6 MED24 CRSP100, CRSP4, DRIP100, KIAA0130, MED5, THRAP4, TRAP100 ENSG00000008838 Mediator complex subunit 24 17 40019097-40061215 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all testis: 64.2 MED25 ACID1, ARC92, DKFZp434K0512, TCBAP0758 ENSG00000104973 Mediator complex subunit 25 19 49818279-49838816 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA068802 Supported Nucleoplasm Head and neck cancer:9.85e-4 (favourable) Expressed in all Expressed in all testis: 111.3 MED27 CRSP34, CRSP8, MED3, TRAP37 ENSG00000160563 Mediator complex subunit 27 9 131860107-132079908 Predicted intracellular proteins Evidence at protein level HPA007002 Approved Supported Nucleus
Nucleoli
Cytosol Cervical cancer:1.59e-4 (favourable) Expressed in all Expressed in all testis: 29.1 MED28 DKFZP434N185, EG1, magicin ENSG00000118579 Mediator complex subunit 28 4 17614631-17634105 Predicted intracellular proteins Evidence at protein level HPA035900, HPA035901 Uncertain Supported Nucleoplasm Expressed in all Expressed in all lymph node: 47.4 MED29 DKFZp434H247, IXL, MED2 ENSG00000063322 Mediator complex subunit 29 19 39391303-39400637 Predicted intracellular proteins Evidence at protein level HPA055956 Supported Nucleoplasm Renal cancer:5.15e-5 (favourable), Endometrial cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 63.6 MED30 THRAP6, TRAP25 ENSG00000164758 Mediator complex subunit 30 8 117520713-117540262 Predicted intracellular proteins Evidence at protein level HPA045767 Approved Nucleoplasm Renal cancer:1.70e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 27.9 MED31 CGI-125, Soh1 ENSG00000108590 Mediator complex subunit 31 17 6643315-6651634 Predicted intracellular proteins Evidence at protein level HPA035947 Uncertain Approved Nucleus Expressed in all Expressed in all testis: 31.0 MED4 DRIP36, HSPC126, TRAP36, VDRIP ENSG00000136146 Mediator complex subunit 4 13 48053323-48095131 Predicted intracellular proteins Evidence at protein level HPA006232 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 102.8 MED6 NY-REN-28 ENSG00000133997 Mediator complex subunit 6 14 70581257-70600690 Predicted intracellular proteins Evidence at protein level HPA030764, HPA069039 Approved Validated Nucleoplasm Liver cancer:1.04e-4 (unfavourable), Melanoma:2.75e-4 (unfavourable) Expressed in all Expressed in all lymph node: 29.0 MED7 CRSP33, CRSP9 ENSG00000155868 Mediator complex subunit 7 5 157137412-157159019 Predicted intracellular proteins Evidence at protein level HPA067181 Supported Nuclear bodies Liver cancer:2.37e-5 (unfavourable), Renal cancer:8.69e-5 (favourable) Expressed in all Expressed in all testis: 46.4 MED8 ARC32, MGC17544, MGC19641 ENSG00000159479 Mediator complex subunit 8 1 43383917-43389808 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028377, HPA028438 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:1.11e-7 (unfavourable), Liver cancer:2.04e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 41.5 MED9 FLJ10193, MED25 ENSG00000141026 Mediator complex subunit 9 17 17476986-17493226 Predicted intracellular proteins Evidence at protein level HPA056415 Uncertain Approved Nucleoplasm
Midbody Renal cancer:2.83e-9 (favourable), Pancreatic cancer:4.18e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 22.1 MEF2A RSRFC4, RSRFC9 ENSG00000068305 Myocyte enhancer factor 2A 15 99565417-99716466 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004499, HPA046597 Approved Supported Nucleoplasm Renal cancer:6.93e-4 (favourable), Stomach cancer:7.96e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 68.4 MEF2C ENSG00000081189 Myocyte enhancer factor 2C 5 88717117-88904257 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005533, CAB068196, CAB068197 Supported Supported Nucleoplasm
Vesicles Renal cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 221.1 MEF2D ENSG00000116604 Myocyte enhancer factor 2D 1 156463727-156500828 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004807, HPA007114 Supported Validated Nucleoplasm Renal cancer:7.53e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 55.5 MEGF8 C19orf49, EGFL4, FLJ22365, SBP1 ENSG00000105429 Multiple EGF-like-domains 8 19 42325609-42378769 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049248 Approved Renal cancer:2.17e-7 (favourable), Pancreatic cancer:6.03e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 38.1 MEGF9 EGFL5 ENSG00000106780 Multiple EGF-like-domains 9 9 120600813-120714470 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA014319, HPA050238 Uncertain Approved Nucleus
Cytosol Renal cancer:5.48e-11 (favourable) Expressed in all Expressed in all thyroid gland: 47.1 MEIS1 ENSG00000143995 Meis homeobox 1 2 66433452-66573869 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB011521, HPA056000, HPA058641 Approved Supported Nucleoplasm Head and neck cancer:2.70e-5 (favourable), Renal cancer:1.69e-4 (unfavourable) Tissue enhanced Expressed in all endometrium: 91.8 MEMO1 C2orf4, CGI-27, MEMO ENSG00000162959 Mediator of cell motility 1 2 31865060-32011230 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042603, HPA057952 Approved Approved Vesicles Mixed Expressed in all testis: 117.5 MEN1 ENSG00000133895 Multiple endocrine neoplasia I 11 64803510-64811294 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030342 Uncertain Supported Nucleoplasm
Cytosol Stomach cancer:6.31e-5 (favourable), Liver cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 22.2 MEPCE BCDIN3, FLJ20257, MePCE ENSG00000146834 Methylphosphate capping enzyme 7 100428790-100434126 Predicted intracellular proteins Evidence at protein level CAB026384, HPA051587 Supported Approved Nucleoplasm
Cell Junctions Renal cancer:1.01e-10 (favourable), Endometrial cancer:6.01e-6 (unfavourable) Expressed in all Expressed in all testis: 87.7 MESDC2 BOCA, KIAA0081, MESD ENSG00000117899 Mesoderm development candidate 2 15 80946289-80989878 Predicted secreted proteins Evidence at protein level HPA039414, HPA041721 Approved Supported Nuclear bodies
Endoplasmic reticulum
Cytosol Ovarian cancer:1.12e-4 (favourable), Endometrial cancer:2.31e-4 (favourable) Expressed in all Expressed in all thyroid gland: 55.6 METAP1 KIAA0094, MAP1A, MetAP1A ENSG00000164024 Methionyl aminopeptidase 1 4 98995620-99062813 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025485, HPA037997, HPA037998 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:2.28e-5 (unfavourable), Liver cancer:3.08e-5 (unfavourable), Renal cancer:1.72e-4 (favourable), Colorectal cancer:7.22e-4 (favourable), Urothelial cancer:9.31e-4 (favourable) Expressed in all Expressed in all testis: 76.9 METAP2 MAP2, MNPEP, p67 ENSG00000111142 Methionyl aminopeptidase 2 12 95473520-95515839 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013025, HPA019095 Supported Supported Plasma membrane
Cytosol Liver cancer:4.51e-6 (unfavourable) Expressed in all Expressed in all seminal vesicle: 141.9 METTL1 C12orf1, TRM8, TRMT8 ENSG00000037897 Methyltransferase like 1 12 57768471-57772793 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020914, HPA050450 Uncertain Validated Nucleus Renal cancer:3.55e-6 (unfavourable), Liver cancer:4.25e-6 (unfavourable) Expressed in all Expressed in all epididymis: 22.4 METTL13 CGI-01, KIAA0859 ENSG00000010165 Methyltransferase like 13 1 171781664-171814023 Predicted intracellular proteins Evidence at protein level HPA044498, HPA053705 Approved Approved Cytosol Liver cancer:5.68e-4 (unfavourable) Expressed in all Expressed in all testis: 24.7 METTL14 KIAA1627 ENSG00000145388 Methyltransferase like 14 4 118685368-118715433 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA038002 Supported Supported Nucleoplasm Renal cancer:1.46e-5 (favourable) Expressed in all Expressed in all testis: 23.5 METTL16 METT10D, MGC3329 ENSG00000127804 Methyltransferase like 16 17 2405562-2511891 Predicted intracellular proteins Evidence at protein level HPA020352, HPA059798 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:3.06e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.1 METTL17 FLJ20859, METT11D1 ENSG00000165792 Methyltransferase like 17 14 20989770-20997035 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002955, HPA059802 Uncertain Validated Nucleus Expressed in all Expressed in all adrenal gland: 23.9 METTL21A FAM119A, HCA557b, HSPA-KMT, LOC151194 ENSG00000144401 Methyltransferase like 21A 2 207580631-207625928 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034712 Uncertain Approved Nucleus
Cytosol Liver cancer:1.87e-5 (unfavourable), Renal cancer:5.43e-4 (unfavourable) Expressed in all Expressed in all spleen: 22.4 METTL21B DKFZP586D0919, FAM119B ENSG00000123427 Methyltransferase like 21B 12 57771492-57782798 Predicted intracellular proteins Evidence at protein level HPA043020 Uncertain Approved Nucleoplasm Expressed in all Expressed in all thyroid gland: 17.0 METTL23 C17orf95, LOC124512 ENSG00000181038 Methyltransferase like 23 17 76726830-76733936 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:3.93e-7 (unfavourable), Liver cancer:4.18e-6 (unfavourable) Expressed in all Expressed in all testis: 85.6 METTL2B FLJ11350, METL, METTL2 ENSG00000165055 Methyltransferase like 2B 7 128476729-128506602 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all skin: 12.9 METTL3 M6A, MT-A70, Spo8 ENSG00000165819 Methyltransferase like 3 14 21498133-21511375 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:2.19e-5 (unfavourable), Pancreatic cancer:2.72e-4 (favourable), Ovarian cancer:2.78e-4 (favourable) Expressed in all Expressed in all parathyroid gland,testis: 33.6 METTL4 FLJ23017, HsT661 ENSG00000101574 Methyltransferase like 4 18 2537525-2571509 Predicted intracellular proteins Evidence at protein level HPA040061 Approved Approved Mitochondria Expressed in all Expressed in all thyroid gland: 17.2 METTL5 HSPC133 ENSG00000138382 Methyltransferase like 5 2 169810081-169824931 Predicted intracellular proteins Evidence at protein level HPA038223 Uncertain Approved Nucleoli
Cytosol Renal cancer:3.06e-8 (unfavourable), Liver cancer:6.64e-5 (unfavourable) Expressed in all Expressed in all epididymis: 75.3 METTL6 MGC24132 ENSG00000206562 Methyltransferase like 6 3 15381275-15440566 Predicted intracellular proteins Evidence at protein level HPA035166 Uncertain Approved Vesicles Liver cancer:2.66e-6 (unfavourable) Expressed in all Expressed in all testis: 33.7 METTL7A DKFZP586A0522 ENSG00000185432 Methyltransferase like 7A 12 50923472-50932517 Predicted membrane proteins Evidence at protein level HPA017434 Supported Lipid droplets Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all thyroid gland: 402.1 METTL9 DREV1 ENSG00000197006 Methyltransferase like 9 16 21597218-21657473 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053588, HPA056347 Uncertain Approved Nucleus
Cell Junctions
Cytosol Liver cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all kidney: 182.7 MEX3C FLJ38871, RKHD2, RNF194 ENSG00000176624 Mex-3 RNA binding family member C 18 51174550-51218304 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040603 Uncertain Approved Vesicles Liver cancer:8.49e-5 (unfavourable) Expressed in all Expressed in all testis: 81.3 MFAP1 ENSG00000140259 Microfibrillar-associated protein 1 15 43804492-43824802 Predicted intracellular proteins Evidence at protein level HPA042370 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.04e-9 (favourable), Liver cancer:2.50e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.6 MFAP3 ENSG00000037749 Microfibrillar-associated protein 3 5 154038906-154220478 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015883, HPA049198 Approved Approved Nucleoplasm
Golgi apparatus Cervical cancer:4.28e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.4 MFAP4 ENSG00000166482 Microfibrillar-associated protein 4 17 19383442-19387240 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA054097 Supported Approved Endoplasmic reticulum Renal cancer:6.83e-7 (unfavourable), Head and neck cancer:3.51e-4 (favourable), Ovarian cancer:4.64e-4 (unfavourable), Urothelial cancer:7.12e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 976.6 MFAP5 MAGP2, MP25 ENSG00000197614 Microfibrillar associated protein 5 12 8637346-8662888 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010553 Supported Urothelial cancer:5.81e-4 (unfavourable), Stomach cancer:6.87e-4 (unfavourable) Mixed Expressed in all smooth muscle: 205.4 MFF C2orf33, GL004 ENSG00000168958 Mitochondrial fission factor 2 227325151-227357836 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010968, HPA074625 Approved Supported Mitochondria Liver cancer:1.20e-4 (unfavourable) Expressed in all Expressed in all testis: 351.8 MFGE8 BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10 ENSG00000140545 Milk fat globule-EGF factor 8 protein 15 88898683-88913411 Cancer-related genes, Predicted secreted proteins Evidence at protein level CAB002753, HPA002807 Uncertain Approved Cytosol Renal cancer:6.06e-9 (unfavourable), Stomach cancer:3.08e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 288.2 MFN1 FLJ20693 ENSG00000171109 Mitofusin 1 3 179347692-179394931 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB033437, HPA059230 Approved Supported Mitochondria Liver cancer:8.08e-5 (unfavourable), Endometrial cancer:6.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 20.2 MFN2 CMT2A2, CPRP1, KIAA0214, MARF ENSG00000116688 Mitofusin 2 1 11980181-12013514 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030554 Uncertain Renal cancer:2.36e-8 (favourable) Expressed in all Expressed in all heart muscle: 197.9 MFSD1 FLJ14153, UG0581B09 ENSG00000118855 Major facilitator superfamily domain containing 1 3 158732198-158829719 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA057924, HPA065858 Approved Approved Nucleus
Nucleoli Renal cancer:5.60e-5 (favourable) Expressed in all Expressed in all spleen: 35.8 MFSD10 IT10C3, TETRAN ENSG00000109736 Major facilitator superfamily domain containing 10 4 2930561-2934859 Predicted membrane proteins Evidence at protein level HPA043209 Uncertain Approved Nucleoplasm
Nuclear membrane Renal cancer:5.68e-5 (unfavourable), Liver cancer:4.49e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 41.3 MFSD11 FLJ20226, FLJ22196 ENSG00000092931 Major facilitator superfamily domain containing 11 17 76735865-76781449 Predicted membrane proteins Evidence at protein level HPA022001 Uncertain Approved Nuclear speckles Endometrial cancer:7.69e-4 (unfavourable), Urothelial cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.9 MFSD12 C19orf28, MGC20700, PP3501 ENSG00000161091 Major facilitator superfamily domain containing 12 19 3538261-3574290 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042149, HPA043088 Uncertain Approved Nucleoplasm
Mitochondria Endometrial cancer:5.66e-6 (favourable), Lung cancer:2.34e-4 (unfavourable), Liver cancer:6.61e-4 (unfavourable), Stomach cancer:7.70e-4 (favourable) Tissue enriched Expressed in all skin: 64.2 MFSD3 ENSG00000167700 Major facilitator superfamily domain containing 3 8 144509074-144511213 Predicted membrane proteins Evidence at protein level HPA056013 Uncertain Approved Vesicles Renal cancer:5.44e-7 (favourable), Cervical cancer:5.08e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.2 MFSD5 MGC11308 ENSG00000182544 Major facilitator superfamily domain containing 5 12 53251251-53254405 Predicted membrane proteins Evidence at protein level HPA039773 Uncertain Liver cancer:1.43e-6 (unfavourable) Expressed in all Expressed in all skin: 49.7 MFSD6 FLJ20160 ENSG00000151690 Major facilitator superfamily domain containing 6 2 190408355-190509205 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA022274 Approved Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:1.05e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 79.2 MFSD8 CLN7, MGC33302 ENSG00000164073 Major facilitator superfamily domain containing 8 4 127917805-127965995 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA044802 Approved Supported Nucleoplasm
Vesicles Urothelial cancer:2.21e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 12.2 MGA FLJ12634, KIAA0518, MAD5, MXD5 ENSG00000174197 MGA, MAX dimerization protein 15 41621224-41773081 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA042278, HPA058183 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 16.0 MGAT1 GLCNAC-TI, GLYT1, GNT-1, MGAT ENSG00000131446 Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 5 180784782-180815652 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017432 Approved Renal cancer:8.65e-4 (unfavourable) Expressed in all Expressed in all spleen: 120.7 MGAT2 GNT-II ENSG00000168282 Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 14 49620795-49623481 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA043721, HPA056824 Approved Supported Golgi apparatus Cervical cancer:3.22e-4 (unfavourable) Expressed in all Expressed in all testis: 44.8 MGAT4B GnT-Ivb ENSG00000161013 Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B 5 179797597-179806952 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA052134 Uncertain Glioma:8.53e-5 (unfavourable), Renal cancer:5.78e-4 (favourable) Expressed in all Expressed in all small intestine: 314.0 MGEA5 MEA5, NCOAT, OGA ENSG00000198408 Meningioma expressed antigen 5 (hyaluronidase) 10 101784443-101818465 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036141, HPA076501 Approved Supported Cytosol Colorectal cancer:8.69e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 127.3 MGLL HU-K5, MGL ENSG00000074416 Monoglyceride lipase 3 127689062-127823250 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011348, HPA011993, HPA011994 Approved Supported Nucleoplasm Pancreatic cancer:6.41e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 188.0 MGME1 bA504H3.4, C20orf72, DDK1 ENSG00000125871 Mitochondrial genome maintenance exonuclease 1 20 17968913-17991122 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040913 Approved Supported Mitochondria Liver cancer:6.98e-8 (unfavourable), Renal cancer:1.13e-7 (unfavourable) Expressed in all Expressed in all skin: 39.8 MGMT ENSG00000170430 O-6-methylguanine-DNA methyltransferase 10 129467184-129768007 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002786, HPA032135, HPA032136 Approved Validated Nucleoplasm Liver cancer:1.54e-4 (favourable), Cervical cancer:9.42e-4 (favourable) Expressed in all Expressed in all fallopian tube: 25.8 MGRN1 KIAA0544, RNF156 ENSG00000102858 Mahogunin ring finger 1, E3 ubiquitin protein ligase 16 4616493-4690974 Predicted intracellular proteins Evidence at protein level HPA007653 Approved Expressed in all Expressed in all cerebral cortex: 56.6 MGST1 GST12, MGST-I ENSG00000008394 Microsomal glutathione S-transferase 1 12 16347142-16609259 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044840 Supported Approved Endoplasmic reticulum
Mitochondria Thyroid cancer:1.97e-4 (favourable), Renal cancer:7.45e-4 (unfavourable) Expressed in all Expressed in all liver: 1596.8 MGST2 MGST-II ENSG00000085871 Microsomal glutathione S-transferase 2 4 139665768-139740745 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA010707 Approved Approved Nucleoplasm Renal cancer:3.22e-9 (favourable), Endometrial cancer:5.26e-5 (favourable) Expressed in all Expressed in all liver: 177.4 MGST3 GST-III ENSG00000143198 Microsomal glutathione S-transferase 3 1 165630861-165661796 Enzymes, Predicted membrane proteins Evidence at protein level HPA053311 Approved Nucleus Expressed in all Expressed in all epididymis: 621.5 MIA3 FLJ39207, KIAA0268, TANGO, UNQ6077 ENSG00000154305 Melanoma inhibitory activity family, member 3 1 222618086-222668012 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055922, HPA056816 Supported Validated Vesicles Renal cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all testis: 80.7 MIB1 DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6 ENSG00000101752 Mindbomb E3 ubiquitin protein ligase 1 18 21704957-21870957 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019100, CAB037044 Approved Approved Nuclear membrane
Vesicles
Plasma membrane Expressed in all Expressed in all thyroid gland: 24.1 MICAL3 KIAA0819 ENSG00000243156 Microtubule associated monooxygenase, calponin and LIM domain containing 3 22 17787649-18024559 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000639, HPA003421, HPA034882 Uncertain Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 69.7 MICALL1 KIAA1668, MICAL-L1, MIRAB13 ENSG00000100139 MICAL-like 1 22 37905657-37942822 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043480, HPA051956 Uncertain Supported Cell Junctions
Microtubule organizing center
Cytosol Liver cancer:3.08e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 50.6 MICU1 CALC, CBARA1, EFHA3, FLJ12684 ENSG00000107745 Mitochondrial calcium uptake 1 10 72367327-72626191 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA037479, HPA037480 Uncertain Supported Mitochondria Renal cancer:4.66e-7 (favourable) Expressed in all Expressed in all kidney: 107.0 MICU2 EFHA1 ENSG00000165487 Mitochondrial calcium uptake 2 13 21492691-21604214 Predicted intracellular proteins, Transporters Evidence at protein level HPA045511, HPA058790 Approved Approved Nucleus
Mitochondria Renal cancer:1.40e-7 (favourable) Expressed in all Expressed in all kidney: 77.9 MID1IP1 FLJ10386, G12-like, MIG12, STRAIT11499, THRSPL ENSG00000165175 MID1 interacting protein 1 X 38801432-38806537 Predicted intracellular proteins Evidence at protein level HPA038816 Uncertain Renal cancer:1.15e-4 (favourable), Liver cancer:2.20e-4 (unfavourable), Urothelial cancer:8.06e-4 (favourable) Expressed in all Expressed in all bone marrow: 66.3 MIDN ENSG00000167470 Midnolin 19 1248553-1259140 Predicted intracellular proteins Evidence at protein level HPA042018, HPA049432 Uncertain Approved Nucleoplasm Expressed in all Expressed in all bone marrow: 51.6 MIEF1 FLJ20232, MiD51, SMCR7L ENSG00000100335 Mitochondrial elongation factor 1 22 39499432-39518132 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA061059 Approved Intermediate filaments
Mitochondria Renal cancer:3.96e-5 (favourable) Expressed in all Expressed in all testis: 22.4 MIEF2 MGC23130, MiD49, SMCR7 ENSG00000177427 Mitochondrial elongation factor 2 17 18260534-18266552 Predicted membrane proteins Evidence at protein level HPA042334 Uncertain Renal cancer:1.75e-7 (favourable) Expressed in all Expressed in all skeletal muscle: 14.1 MIEN1 C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4 ENSG00000141741 Migration and invasion enhancer 1 17 39728496-39730787 Predicted intracellular proteins Evidence at protein level HPA061344 Approved Expressed in all Expressed in all cerebral cortex: 40.8 MIER1 hMI-ER1, KIAA1610, MI-ER1 ENSG00000198160 Mesoderm induction early response 1, transcriptional regulator 1 66924895-66988619 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA019589, HPA050306 Supported Validated Nucleoplasm Glioma:6.18e-8 (favourable), Colorectal cancer:4.96e-4 (favourable) Expressed in all Expressed in all bone marrow: 63.2 MIER3 DKFZp686L09111, DKFZp781I1119, FLJ35954 ENSG00000155545 Mesoderm induction early response 1, family member 3 5 56919602-56971675 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058349, HPA065946 Uncertain Validated Nucleoplasm Expressed in all Expressed in all colon: 30.7 MIF GIF, GLIF ENSG00000240972 Macrophage migration inhibitory factor (glycosylation-inhibiting factor) 22 23894004-23895227 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003868, CAB005284 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 40.6 MIF4GD AD023, MGC45027, MIFD ENSG00000125457 MIF4G domain containing 17 75266228-75271227 Predicted intracellular proteins Evidence at protein level HPA051222 Approved Supported Nucleoli
Cytosol Pancreatic cancer:2.70e-4 (favourable) Expressed in all Expressed in all lymph node: 46.5 MIIP FLJ12438, IIp45 ENSG00000116691 Migration and invasion inhibitory protein 1 12019466-12032045 Predicted intracellular proteins Evidence at protein level HPA044948 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:8.26e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 27.5 MINA FLJ14393, mdig, MINA53 ENSG00000170854 MYC induced nuclear antigen 3 97941818-97972457 Predicted intracellular proteins Evidence at protein level HPA007603, HPA008080, CAB013458 Supported Validated Nucleus
Nucleoli Breast cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 100.5 MINK1 B55, MAP4K6, MINK, YSK2, ZC3 ENSG00000141503 Misshapen-like kinase 1 17 4833388-4898061 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056296 Approved Pancreatic cancer:2.77e-4 (favourable), Liver cancer:3.00e-4 (unfavourable), Prostate cancer:9.27e-4 (unfavourable) Expressed in all Expressed in all skin: 72.6 MINOS1 C1orf151, FLJ36999, Mic10, MIO10, RP5-1056L3.2 ENSG00000173436 Mitochondrial inner membrane organizing system 1 1 19596977-19629821 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059930 Supported Supported Mitochondria Liver cancer:7.23e-4 (unfavourable), Urothelial cancer:8.11e-4 (favourable) Expressed in all Expressed in all prostate: 13.3 MINPP1 MIPP ENSG00000107789 Multiple inositol-polyphosphate phosphatase 1 10 87504875-87553460 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026859 Approved Renal cancer:6.98e-5 (unfavourable) Expressed in all Expressed in all placenta: 27.3 MIOS FLJ20323 ENSG00000164654 Missing oocyte, meiosis regulator, homolog (Drosophila) 7 7566872-7608929 Predicted intracellular proteins Evidence at protein level HPA042928, HPA052223 Approved Validated Nucleoplasm
Cytosol Renal cancer:3.28e-6 (favourable), Endometrial cancer:6.51e-4 (favourable), Liver cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 53.8 MIPEP MIP ENSG00000027001 Mitochondrial intermediate peptidase 13 23730189-23889419 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030676, HPA031669, HPA031670 Approved Validated Mitochondria Renal cancer:7.66e-12 (favourable) Expressed in all Expressed in all fallopian tube: 27.1 MIS12 hMIS12, KNTC2AP, MGC2488, MTW1 ENSG00000167842 MIS12 kinetochore complex component 17 5486285-5490814 Predicted intracellular proteins Evidence at protein level HPA044482 Approved Pancreatic cancer:8.00e-4 (favourable) Expressed in all Expressed in all epididymis: 39.0 MITD1 LOC129531 ENSG00000158411 MIT, microtubule interacting and transport, domain containing 1 2 99161427-99181058 Predicted intracellular proteins Evidence at protein level HPA036162, HPA036163 Approved Validated Vesicles Renal cancer:1.32e-11 (unfavourable), Urothelial cancer:5.46e-8 (favourable), Liver cancer:1.47e-6 (unfavourable), Breast cancer:5.96e-4 (favourable) Expressed in all Expressed in all lymph node: 44.8 MKKS BBS6 ENSG00000125863 McKusick-Kaufman syndrome 20 10401009-10434222 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041071, HPA044233 Supported Supported Centrosome Renal cancer:3.79e-9 (favourable), Liver cancer:9.84e-5 (unfavourable) Expressed in all Expressed in all testis: 43.5 MKL1 BSAC, KIAA1438, MAL, MRTF-A ENSG00000196588 Megakaryoblastic leukemia (translocation) 1 22 40410281-40636702 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030782 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.58e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 51.3 MKL2 FLJ31823, MRTF-B ENSG00000186260 MKL/myocardin-like 2 16 14071321-14266773 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA011286 Supported Supported Nuclear speckles Renal cancer:6.20e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.3 MKLN1 TWA2 ENSG00000128585 Muskelin 1, intracellular mediator containing kelch motifs 7 131110096-131496636 Predicted intracellular proteins Evidence at protein level HPA022817, HPA041810 Approved Approved Vesicles
Plasma membrane
Cytosol Expressed in all Expressed in all prostate: 25.2 MKNK1 MNK1 ENSG00000079277 MAP kinase interacting serine/threonine kinase 1 1 46557408-46616843 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA071293 Supported Nucleoplasm Liver cancer:1.24e-5 (unfavourable), Renal cancer:1.51e-5 (unfavourable), Cervical cancer:7.05e-4 (favourable) Expressed in all Expressed in all appendix: 45.4 MKNK2 GPRK7, MNK2 ENSG00000099875 MAP kinase interacting serine/threonine kinase 2 19 2037465-2051244 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021875, CAB037253, HPA053989 Supported Supported Nucleus
Nucleoli
Nuclear bodies Endometrial cancer:4.86e-5 (favourable), Stomach cancer:4.01e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 174.4 MKRN1 RNF61 ENSG00000133606 Makorin ring finger protein 1 7 140453040-140479569 Predicted intracellular proteins Evidence at protein level HPA000567 Approved Nucleus
Nuclear membrane
Cytosol Expressed in all Expressed in all testis: 223.7 MKRN2 HSPC070, RNF62 ENSG00000075975 Makorin ring finger protein 2 3 12557014-12583713 Predicted intracellular proteins Evidence at protein level HPA037559, HPA037560 Approved Approved Nucleoplasm
Cytosol Liver cancer:1.58e-4 (unfavourable), Renal cancer:6.04e-4 (favourable) Expressed in all Expressed in all testis: 99.8 MKS1 BBS13, FLJ20345, MKS, POC12 ENSG00000011143 Meckel syndrome, type 1 17 58205437-58219605 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021372, HPA021812 Approved Pancreatic cancer:1.25e-4 (favourable), Renal cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 32.0 MLEC KIAA0152 ENSG00000110917 Malectin 12 120686869-120701864 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Endometrial cancer:9.60e-6 (favourable), Stomach cancer:8.77e-4 (favourable) Expressed in all Expressed in all thyroid gland: 161.6 MLF2 NTN4 ENSG00000089693 Myeloid leukemia factor 2 12 6747996-6767475 Predicted intracellular proteins Evidence at protein level HPA010811, HPA010859 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all cerebral cortex: 273.3 MLH1 COCA2, FCC2, HNPCC, HNPCC2 ENSG00000076242 MutL homolog 1 3 36993332-37050918 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013294, HPA052707, HPA060714, CAB070868 Supported Validated Nucleoplasm Liver cancer:8.24e-5 (unfavourable) Expressed in all Expressed in all testis: 59.7 MLH3 ENSG00000119684 MutL homolog 3 14 75013764-75051532 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060570 Approved Nucleus Expressed in all Expressed in all parathyroid gland: 23.9 MLLT1 ENL, LTG19, YEATS1 ENSG00000130382 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 19 6210379-6279948 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031166 Approved Supported Nucleoplasm Head and neck cancer:6.03e-5 (favourable) Expressed in all Expressed in all placenta: 61.2 MLLT10 AF10 ENSG00000078403 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 10 21524675-21743630 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA005747 Supported Supported Nucleoplasm Head and neck cancer:8.75e-4 (favourable) Expressed in all Expressed in all testis: 176.8 MLLT4 AF-6, AF6 ENSG00000130396 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 6 167826922-167972023 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868 Approved Validated Nucleoplasm
Plasma membrane
Cell Junctions Breast cancer:7.43e-5 (unfavourable) Expressed in all Expressed in all esophagus: 111.1 MLLT6 AF17, FLJ23480 ENSG00000275023 Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 17 38705542-38729803 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA004021 Approved Approved Nucleus Head and neck cancer:3.98e-4 (favourable), Breast cancer:4.18e-4 (favourable), Pancreatic cancer:7.41e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 35.2 MLST8 GbetaL, GBL, Lst8, Pop3 ENSG00000167965 MTOR associated protein, LST8 homolog 16 2204248-2209416 Predicted intracellular proteins Evidence at protein level CAB019935, HPA041841 Approved Approved Nucleoplasm
Golgi apparatus
Cell Junctions Renal cancer:7.60e-4 (favourable) Expressed in all Expressed in all testis: 28.7 MLX bHLHd13, MAD7, MXD7, TCFL4 ENSG00000108788 MLX, MAX dimerization protein 17 42567068-42573239 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB025329, HPA052766, HPA064438 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all Expressed in all duodenum: 47.6 MLXIP bHLHe36, KIAA0867, MIR, MONDOA ENSG00000175727 MLX interacting protein 12 122078722-122147347 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA023084 Approved Liver cancer:2.28e-4 (unfavourable), Renal cancer:2.92e-4 (unfavourable) Expressed in all Expressed in all rectum: 24.8 MMAB cblB, CFAP23 ENSG00000139428 Methylmalonic aciduria (cobalamin deficiency) cblB type 12 109553737-109573874 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039017 Approved Approved Mitochondria Renal cancer:1.55e-4 (favourable) Expressed in all Expressed in all adrenal gland: 32.7 MMADHC C2orf25, cblD, CL25022 ENSG00000168288 Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2 149569634-149587816 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037531, HPA037532 Supported Pancreatic cancer:2.73e-4 (unfavourable) Expressed in all Expressed in all testis: 122.3 MMGT1 EMC5, TMEM32 ENSG00000169446 Membrane magnesium transporter 1 X 135962070-135974063 Predicted membrane proteins Evidence at protein level HPA032037 Approved Renal cancer:1.94e-5 (favourable), Breast cancer:8.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 34.4 MMP24-AS1 ENSG00000126005 MMP24 antisense RNA 1 20 35201745-35278131 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all adipose tissue: 46.8 MMRN2 EMILIN3, EndoGlyx-1, FLJ13465 ENSG00000173269 Multimerin 2 10 86935540-86969481 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020741 Approved Approved Vesicles Expressed in all Expressed in all placenta: 101.0 MMS19 hMMS19, MET18, MMS19L ENSG00000155229 MMS19 homolog, cytosolic iron-sulfur assembly component 10 97458324-97498794 Predicted intracellular proteins Evidence at protein level HPA051936, HPA056299 Approved Validated Nucleoplasm Urothelial cancer:3.39e-4 (unfavourable), Liver cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all testis: 52.6 MNAT1 MAT1, RNF66 ENSG00000020426 MNAT CDK-activating kinase assembly factor 1 14 60734742-60969953 Predicted intracellular proteins Evidence at protein level HPA000701, HPA001154, CAB004495 Approved Validated Nucleoplasm Head and neck cancer:2.45e-4 (unfavourable), Renal cancer:3.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 87.0 MNT bHLHd3, MAD6, MXD6, ROX ENSG00000070444 MAX network transcriptional repressor 17 2384060-2401118 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059532, HPA067578 Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 15.3 MOAP1 MAP-1, PNMA4 ENSG00000165943 Modulator of apoptosis 1 14 93182196-93184928 Predicted intracellular proteins Evidence at protein level HPA000939 Uncertain Approved Nucleus
Cell Junctions Lung cancer:7.37e-9 (favourable), Renal cancer:3.15e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 86.4 MOB1A C2orf6, FLJ10788, FLJ11595, Mats1, MOB1, Mob4B, MOBK1B, MOBKL1B ENSG00000114978 MOB kinase activator 1A 2 74152528-74178898 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047088, HPA071690 Supported Approved Nucleus
Nucleoli
Cytosol Liver cancer:3.34e-4 (unfavourable) Expressed in all Expressed in all lymph node: 109.0 MOB1B MOB4A, MOBKL1A ENSG00000173542 MOB kinase activator 1B 4 70902326-71022449 Predicted intracellular proteins Evidence at protein level HPA047088, HPA071690 Supported Approved Nucleus
Nucleoli
Cytosol Liver cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all kidney: 24.1 MOB2 HCCA2 ENSG00000182208 MOB kinase activator 2 11 1469457-1501247 Predicted intracellular proteins Evidence at protein level HPA046313 Uncertain Supported Nucleus
Nucleoli
Cytosol Renal cancer:2.02e-4 (favourable), Glioma:7.86e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 35.2 MOB3A MOB-LAK, MOB1C, MOBKL2A, moblak ENSG00000172081 MOB kinase activator 3A 19 2071038-2096673 Predicted intracellular proteins Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Endometrial cancer:1.33e-6 (favourable), Renal cancer:1.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 86.5 MOB3C MOB1E, MOBKL2C ENSG00000142961 MOB kinase activator 3C 1 46607715-46616891 Predicted intracellular proteins Evidence at protein level HPA057744 Uncertain Intermediate filaments
Cytosol Cervical cancer:3.16e-5 (favourable) Expressed in all Expressed in all adipose tissue: 20.6 MOB4 2C4D, CGI-95, DKFZP564M112, MOB3, MOBKL3, PHOCN, PREI3 ENSG00000115540 MOB family member 4, phocein 2 197515571-197553699 Predicted intracellular proteins Evidence at protein level CAB034082, HPA044125 Approved Renal cancer:4.68e-4 (unfavourable), Liver cancer:8.29e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 80.0 MOCS2 MOCO1 ENSG00000164172 Molybdenum cofactor synthesis 2 5 53095679-53110063 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037679, HPA037680 Approved Approved Nucleus
Cytosol Renal cancer:3.68e-6 (favourable) Expressed in all Expressed in all kidney: 106.8 MOGS CWH41, DER7, GCS1 ENSG00000115275 Mannosyl-oligosaccharide glucosidase 2 74461057-74465410 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011322, HPA011969 Approved Validated Endoplasmic reticulum Renal cancer:2.79e-8 (unfavourable), Liver cancer:2.34e-6 (unfavourable), Colorectal cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all duodenum: 64.8 MON1B HSRG1, KIAA0872, SAND2 ENSG00000103111 MON1 secretory trafficking family member B 16 77190835-77202405 Predicted intracellular proteins Evidence at protein level HPA046285 Approved Approved Cytosol Renal cancer:9.42e-5 (favourable), Endometrial cancer:6.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 30.2 MON2 KIAA1040 ENSG00000061987 MON2 homolog, regulator of endosome-to-Golgi trafficking 12 62466817-62600479 Predicted intracellular proteins Evidence at protein level HPA038697, HPA057607 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Head and neck cancer:2.03e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 33.5 MORC2 AC004542.C22.1, KIAA0852, ZCW3, ZCWCC1 ENSG00000133422 MORC family CW-type zinc finger 2 22 30925130-30968298 Predicted intracellular proteins Evidence at protein level HPA000436 Supported Supported Nucleus
Cytosol Renal cancer:6.54e-8 (unfavourable) Expressed in all Expressed in all testis: 65.4 MORC3 KIAA0136, NXP2, ZCW5, ZCWCC3 ENSG00000159256 MORC family CW-type zinc finger 3 21 36320189-36386148 Predicted intracellular proteins Evidence at protein level HPA018406, HPA034848 Approved Validated Nucleoplasm
Mitochondria Expressed in all Expressed in all endometrium: 30.7 MORC4 FLJ11565, ZCW4, ZCWCC2 ENSG00000133131 MORC family CW-type zinc finger 4 X 106813871-107000244 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA000395, HPA015547, HPA050250 Supported Validated Nucleoplasm Breast cancer:3.56e-5 (unfavourable) Expressed in all Expressed in all placenta: 113.4 MORF4L1 Eaf3, HsT17725, MEAF3, MORFRG15, MRG15 ENSG00000185787 Mortality factor 4 like 1 15 78810487-78898133 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042360, HPA062010 Approved Supported Nuclear speckles Expressed in all Expressed in all testis: 1063.2 MORF4L2 KIAA0026, MRGX ENSG00000123562 Mortality factor 4 like 2 X 103675496-103688158 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031872, HPA054102 Supported Validated Nucleus Renal cancer:7.86e-7 (unfavourable), Head and neck cancer:4.29e-5 (unfavourable), Breast cancer:9.83e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 488.6 MORN2 MOPT ENSG00000188010 MORN repeat containing 2 2 38875962-38929072 Predicted intracellular proteins Evidence at protein level HPA057815 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 264.0 MORN4 bA548K23.4, C10orf83, FLJ25925, rtp ENSG00000171160 MORN repeat containing 4 10 97614553-97633500 Predicted intracellular proteins Evidence at protein level HPA052718 Uncertain Expressed in all Expressed in all cerebral cortex: 31.9 MOSPD1 dJ473B4 ENSG00000101928 Motile sperm domain containing 1 X 134887626-134915267 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031158 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all fallopian tube: 41.8 MOSPD3 CDS3, NET30 ENSG00000106330 Motile sperm domain containing 3 7 100612102-100615384 Predicted membrane proteins Evidence at protein level HPA041137, HPA048240 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 29.7 MOV10 fSAP113, gb110, MGC2948 ENSG00000155363 Mov10 RISC complex RNA helicase 1 112673141-112700746 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031627 Approved Cytosol Renal cancer:1.48e-11 (unfavourable), Liver cancer:3.44e-4 (unfavourable) Expressed in all Expressed in all placenta: 33.6 MPC1 BRP44L, CGI-129, dJ68L15.3 ENSG00000060762 Mitochondrial pyruvate carrier 1 6 166364919-166383013 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA045119, HPA055790 Supported Validated Mitochondria Renal cancer:4.79e-11 (favourable), Lung cancer:1.29e-4 (favourable), Cervical cancer:1.45e-4 (favourable) Expressed in all Expressed in all heart muscle: 409.2 MPC2 BRP44, DKFZP564B167 ENSG00000143158 Mitochondrial pyruvate carrier 2 1 167916729-167937040 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA056091 Uncertain Expressed in all Expressed in all testis: 353.7 MPDU1 CDGIf, Lec35, PQLC5, SL15 ENSG00000129255 Mannose-P-dolichol utilization defect 1 17 7583529-7592789 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014845 Uncertain Supported Endoplasmic reticulum
Mitochondria Expressed in all Expressed in all rectum: 70.2 MPG MDG ENSG00000103152 N-methylpurine DNA glycosylase 16 77007-85853 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006531 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:2.82e-5 (favourable) Expressed in all Expressed in all thyroid gland: 48.9 MPHOSPH10 CT90, MPP10, MPP10P, PPP1R106 ENSG00000124383 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 2 71130314-71150101 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035059, HPA035060, HPA049907 Supported Validated Nucleoli Renal cancer:3.89e-7 (unfavourable) Expressed in all Expressed in all prostate: 35.0 MPHOSPH6 MPP6 ENSG00000135698 M-phase phosphoprotein 6 16 82147798-82170226 Predicted intracellular proteins Evidence at protein level CAB003674, HPA026948 Approved Supported Nucleus
Nucleoli Ovarian cancer:3.41e-5 (favourable), Liver cancer:4.36e-5 (unfavourable), Prostate cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all breast: 90.9 MPHOSPH8 HSMPP8, mpp8 ENSG00000196199 M-phase phosphoprotein 8 13 19633681-19673459 Predicted intracellular proteins Evidence at protein level HPA039701, HPA040035 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all ovary: 64.5 MPI ENSG00000178802 Mannose phosphate isomerase 15 74890005-74902219 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007200 Approved Approved Plasma membrane
Cytosol Head and neck cancer:2.39e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 51.1 MPND FLJ14981 ENSG00000008382 MPN domain containing 19 4343527-4360086 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043274, HPA045475 Approved Approved Nucleus
Nucleoli Lung cancer:1.55e-4 (favourable), Cervical cancer:2.99e-4 (favourable), Endometrial cancer:6.12e-4 (favourable), Renal cancer:7.04e-4 (favourable) Expressed in all Expressed in all duodenum: 31.8 MPP1 DXS552E, PEMP ENSG00000130830 Membrane protein, palmitoylated 1, 55kDa X 154778684-154821007 Predicted intracellular proteins Evidence at protein level HPA000167 Approved Nucleoli
Nuclear speckles
Cytosol Renal cancer:4.60e-6 (favourable) Expressed in all Expressed in all placenta: 118.7 MPP5 FLJ12615, PALS1 ENSG00000072415 Membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 14 67241109-67335819 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000993 Uncertain Uncertain Nucleoplasm
Plasma membrane
Cytosol Renal cancer:1.71e-12 (favourable), Liver cancer:5.62e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 44.4 MPPE1 ENSG00000154889 Metallophosphoesterase 1 18 11882622-11909223 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012639 Uncertain Approved Nucleoplasm
Golgi apparatus Renal cancer:6.45e-7 (favourable), Melanoma:1.35e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 77.6 MPRIP M-RIP, p116Rip, RHOIP3 ENSG00000133030 Myosin phosphatase Rho interacting protein 17 17042545-17217679 Predicted intracellular proteins Evidence at protein level HPA022034, HPA022901 Supported Supported Actin filaments
Cytosol Expressed in all Expressed in all smooth muscle: 188.5 MPV17 SYM1 ENSG00000115204 MpV17 mitochondrial inner membrane protein 2 27309492-27325680 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Liver cancer:6.99e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 84.1 MPV17L2 FKSG24, MGC12972 ENSG00000254858 MPV17 mitochondrial membrane protein-like 2 19 18193182-18196948 Predicted membrane proteins Evidence at protein level HPA043111 Uncertain Approved Plasma membrane
Cytosol Renal cancer:2.30e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 16.2 MPZL1 FLJ21047, PZR ENSG00000197965 Myelin protein zero-like 1 1 167721192-167791919 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026966, HPA063538 Approved Supported Vesicles
Plasma membrane Renal cancer:3.99e-7 (unfavourable), Liver cancer:4.27e-6 (unfavourable), Lung cancer:3.98e-4 (unfavourable), Thyroid cancer:8.08e-4 (unfavourable) Expressed in all Expressed in all breast: 111.3 MRAS M-RAs, R-RAS3, RRAS3 ENSG00000158186 Muscle RAS oncogene homolog 3 138347648-138405534 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA042728 Approved Approved Vesicles Endometrial cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 114.4 MRC2 CD280, CLEC13E, ENDO180, KIAA0709 ENSG00000011028 Mannose receptor, C type 2 17 62627401-62693597 CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041991 Supported Renal cancer:4.94e-7 (unfavourable), Ovarian cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 39.9 MRE11A ATLD, MRE11 ENSG00000020922 MRE11 homolog A, double strand break repair nuclease 11 94415578-94493908 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002691, CAB004081 Supported Validated Nucleoplasm Liver cancer:7.14e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.8 MRFAP1 PAM14, PGR1 ENSG00000179010 Morf4 family associated protein 1 4 6640091-6642745 Predicted intracellular proteins Evidence at protein level CAB042447, HPA056367 Approved Approved Nucleus Renal cancer:2.90e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 506.5 MRFAP1L1 MGC9651 ENSG00000178988 Morf4 family associated protein 1-like 1 4 6707701-6709880 Predicted intracellular proteins Evidence at protein level Renal cancer:2.80e-5 (favourable), Urothelial cancer:5.26e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 91.5 MRI1 MGC3207, MRDI, mtnA, Ypr118w ENSG00000037757 Methylthioribose-1-phosphate isomerase 1 19 13764532-13774282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042744, CAB045988 Approved Supported Nucleoplasm
Nucleoli fibrillar center
Cytosol Expressed in all Expressed in all placenta: 23.0 MROH1 HEATR7A, KIAA1833 ENSG00000179832 Maestro heat-like repeat family member 1 8 144148016-144261940 Predicted intracellular proteins Evidence at protein level HPA044465 Approved Renal cancer:3.65e-6 (favourable), Endometrial cancer:6.74e-4 (favourable) Expressed in all Expressed in all thyroid gland: 14.9 MRPL1 BM022 ENSG00000169288 Mitochondrial ribosomal protein L1 4 77862520-77952790 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043656 Supported Supported Mitochondria Renal cancer:3.35e-5 (favourable) Expressed in all Expressed in all kidney: 29.3 MRPL10 L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8 ENSG00000159111 Mitochondrial ribosomal protein L10 17 47823272-47831534 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA021234, HPA029885 Supported Validated Mitochondria Liver cancer:6.67e-4 (unfavourable) Expressed in all Expressed in all ovary: 61.0 MRPL11 ENSG00000174547 Mitochondrial ribosomal protein L11 11 66435075-66466738 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA057685 Approved Supported Mitochondria Expressed in all Expressed in all rectum: 26.5 MRPL12 MRPL7, MRPL7/L12, RPML12 ENSG00000262814 Mitochondrial ribosomal protein L12 17 81703357-81707526 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA022853, HPA023043 Supported Supported Mitochondria Lung cancer:2.35e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 57.3 MRPL13 L13, L13A, L13mt, RPL13, RPML13 ENSG00000172172 Mitochondrial ribosomal protein L13 8 120380761-120445402 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA060899 Approved Breast cancer:1.37e-4 (unfavourable) Expressed in all Expressed in all kidney: 48.9 MRPL14 MRP-L32, RPML32 ENSG00000180992 Mitochondrial ribosomal protein L14 6 44113454-44127457 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA038769, HPA076790 Uncertain Supported Mitochondria Renal cancer:7.46e-5 (unfavourable), Thyroid cancer:1.08e-4 (favourable), Ovarian cancer:4.81e-4 (favourable) Expressed in all Expressed in all lung: 85.7 MRPL15 HSPC145, L15mt, MRP-L15, MRP-L7, RPML7 ENSG00000137547 Mitochondrial ribosomal protein L15 8 54135210-54147901 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA044425 Supported Endometrial cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 82.3 MRPL16 FLJ20484, PNAS-111 ENSG00000166902 Mitochondrial ribosomal protein L16 11 59806135-59810872 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA054133 Supported Breast cancer:1.04e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 70.2 MRPL17 MRP-L26, RPML26 ENSG00000158042 Mitochondrial ribosomal protein L17 11 6680782-6683401 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043666, HPA050552 Uncertain Renal cancer:3.15e-7 (unfavourable), Liver cancer:2.59e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.9 MRPL18 HSPC071 ENSG00000112110 Mitochondrial ribosomal protein L18 6 159789812-159798436 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA028774, HPA028775 Approved Renal cancer:9.02e-5 (unfavourable), Liver cancer:3.61e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 84.9 MRPL19 KIAA0104, MRP-L15, RLX1, RPML15 ENSG00000115364 Mitochondrial ribosomal protein L19 2 75646783-75690851 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046805, HPA056622 Approved Supported Mitochondria Pancreatic cancer:1.97e-5 (unfavourable), Colorectal cancer:7.39e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 65.3 MRPL2 CGI-22, MRP-L14, RPML14 ENSG00000112651 Mitochondrial ribosomal protein L2 6 43054029-43059806 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA007455, HPA064814 Approved Approved Nucleoplasm
Mitochondria Ovarian cancer:6.01e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 33.1 MRPL20 FLJ10024 ENSG00000242485 Mitochondrial ribosomal protein L20 1 1401908-1407313 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047074 Supported Supported Mitochondria Expressed in all Expressed in all epididymis: 155.4 MRPL21 ENSG00000197345 Mitochondrial ribosomal protein L21 11 68891276-68903835 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA051657 Approved Approved Nucleoplasm
Mitochondria Head and neck cancer:5.97e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 74.9 MRPL22 HSPC158, MRP-L25, RPML25 ENSG00000082515 Mitochondrial ribosomal protein L22 5 154941070-154969411 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA047063 Uncertain Approved Mitochondria Expressed in all Expressed in all testis: 62.7 MRPL23 L23MRP, RPL23L ENSG00000214026 Mitochondrial ribosomal protein L23 11 1947278-1984522 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050406 Approved Supported Nucleoli fibrillar center
Mitochondria Endometrial cancer:3.97e-4 (favourable) Expressed in all Expressed in all fallopian tube: 88.5 MRPL24 MRP-L18 ENSG00000143314 Mitochondrial ribosomal protein L24 1 156737303-156741590 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA030295 Approved Renal cancer:3.99e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 116.2 MRPL27 ENSG00000108826 Mitochondrial ribosomal protein L27 17 50367857-50373214 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA021416 Approved Expressed in all Expressed in all epididymis: 129.6 MRPL28 MAAT1, p15 ENSG00000086504 Mitochondrial ribosomal protein L28 16 367384-370527 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA030594, CAB033542, HPA055589 Supported Supported Mitochondria Expressed in all Expressed in all cerebral cortex: 71.7 MRPL3 MRL3, RPML3 ENSG00000114686 Mitochondrial ribosomal protein L3 3 131462212-131502983 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043665, HPA060132 Approved Liver cancer:4.33e-7 (unfavourable), Pancreatic cancer:3.51e-6 (unfavourable), Ovarian cancer:1.36e-4 (favourable) Expressed in all Expressed in all thyroid gland: 107.2 MRPL30 MRP-L28, RPML28 ENSG00000185414 Mitochondrial ribosomal protein L30 2 99181079-99197626 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047255 Approved Expressed in all Expressed in all thyroid gland: 20.3 MRPL32 bMRP-59b, HSPC283, L32mt, MRP-L32 ENSG00000106591 Mitochondrial ribosomal protein L32 7 42932200-42948958 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA048965 Uncertain Expressed in all Expressed in all prostate: 73.2 MRPL33 C2orf1, RPL33L ENSG00000243147 Mitochondrial ribosomal protein L33 2 27771717-27988087 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA066872 Approved Liver cancer:1.66e-4 (unfavourable), Head and neck cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 589.1 MRPL34 L34mt, MGC24974, MGC2633 ENSG00000130312 Mitochondrial ribosomal protein L34 19 17292609-17306843 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA049276 Uncertain Renal cancer:4.29e-6 (favourable), Pancreatic cancer:4.87e-4 (favourable) Expressed in all Expressed in all adrenal gland: 76.4 MRPL35 ENSG00000132313 Mitochondrial ribosomal protein L35 2 86199355-86213794 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA043482 Uncertain Renal cancer:9.96e-6 (favourable), Liver cancer:3.51e-4 (unfavourable) Expressed in all Expressed in all rectum: 65.6 MRPL36 BRIP1, L36mt, MRP-L36, PRPL36, RPMJ ENSG00000171421 Mitochondrial ribosomal protein L36 5 1798386-1801366 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047238 Approved Supported Nuclear bodies
Mitochondria Renal cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all testis: 95.3 MRPL37 MRP-L2, RPML2 ENSG00000116221 Mitochondrial ribosomal protein L37 1 54184041-54225464 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA025767, HPA025826, HPA025951 Supported Supported Mitochondria Liver cancer:6.45e-5 (unfavourable), Colorectal cancer:6.99e-4 (favourable), Stomach cancer:9.25e-4 (favourable) Expressed in all Expressed in all fallopian tube: 61.1 MRPL38 HSPC262, MGC4810, MRP-L3, RPML3 ENSG00000204316 Mitochondrial ribosomal protein L38 17 75898643-75905413 Predicted intracellular proteins Evidence at protein level HPA023054, HPA023135 Approved Supported Mitochondria Urothelial cancer:9.21e-5 (favourable), Pancreatic cancer:4.23e-4 (favourable), Renal cancer:5.58e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 30.2 MRPL39 C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5 ENSG00000154719 Mitochondrial ribosomal protein L39 21 25585656-25607517 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA018331 Approved Pancreatic cancer:5.84e-4 (unfavourable) Expressed in all Expressed in all testis: 94.1 MRPL4 CGI-28 ENSG00000105364 Mitochondrial ribosomal protein L4 19 10251901-10260045 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051261 Approved Expressed in all Expressed in all cerebral cortex: 39.0 MRPL40 MRP-L22, NLVCF ENSG00000185608 Mitochondrial ribosomal protein L40 22 19431902-19436075 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006181 Approved Validated Nucleoli
Mitochondria Cervical cancer:7.57e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.6 MRPL41 BMRP, MRP-L27, MRPL27, PIG3, RPML27 ENSG00000182154 Mitochondrial ribosomal protein L41 9 137551199-137552555 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA024550, HPA027160 Supported Supported Mitochondria Expressed in all Expressed in all skeletal muscle: 59.8 MRPL42 HSPC204, MRP-L31, MRPL31, MRPS32, PTD007, RPML31 ENSG00000198015 Mitochondrial ribosomal protein L42 12 93467488-93516213 Predicted intracellular proteins Evidence at protein level HPA039398 Approved Supported Plasma membrane
Mitochondria Liver cancer:7.49e-4 (unfavourable), Urothelial cancer:8.12e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.2 MRPL43 bMRP36a ENSG00000055950 Mitochondrial ribosomal protein L43 10 100969458-100987515 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA073022 Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all thyroid gland: 57.8 MRPL44 FLJ12701, FLJ13990 ENSG00000135900 Mitochondrial ribosomal protein L44 2 223957404-223967714 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038147, HPA038148 Approved Approved Nucleus
Plasma membrane
Mitochondria Liver cancer:1.29e-4 (unfavourable), Renal cancer:2.02e-4 (favourable) Expressed in all Expressed in all kidney: 37.2 MRPL46 C15orf4, LIECG2, P2ECSL ENSG00000259494 Mitochondrial ribosomal protein L46 15 88459476-88467419 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050166 Uncertain Supported Nucleoplasm
Cell Junctions
Mitochondria Renal cancer:2.09e-6 (favourable) Expressed in all Expressed in all adrenal gland: 50.5 MRPL47 CGI-204, NCM1 ENSG00000136522 Mitochondrial ribosomal protein L47 3 179588285-179604654 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA037553, HPA047779 Approved Validated Mitochondria Endometrial cancer:3.15e-4 (unfavourable), Cervical cancer:6.44e-4 (favourable) Expressed in all Expressed in all testis: 84.5 MRPL48 CGI-118 ENSG00000175581 Mitochondrial ribosomal protein L48 11 73787316-73865133 Predicted intracellular proteins Evidence at protein level HPA040241, HPA040864 Approved Liver cancer:3.30e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.6 MRPL49 C11orf4, L49mt, NOF, NOF1 ENSG00000149792 Mitochondrial ribosomal protein L49 11 65122183-65127371 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046778 Approved Renal cancer:4.22e-15 (favourable), Breast cancer:3.79e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 83.8 MRPL50 FLJ20493, MRP-L50 ENSG00000136897 Mitochondrial ribosomal protein L50 9 101387633-101398614 Predicted intracellular proteins Evidence at protein level HPA022925 Approved Renal cancer:1.21e-10 (favourable) Expressed in all Expressed in all adrenal gland: 20.9 MRPL51 bMRP64, CDA09, HSPC241, MRP64 ENSG00000111639 Mitochondrial ribosomal protein L51 12 6491886-6493841 Predicted intracellular proteins Evidence at protein level HPA039923 Approved Supported Mitochondria Expressed in all Expressed in all testis: 233.5 MRPL52 ENSG00000172590 Mitochondrial ribosomal protein L52 14 22829879-22835037 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA012319 Approved Approved Mitochondria Expressed in all Expressed in all appendix: 74.7 MRPL53 ENSG00000204822 Mitochondrial ribosomal protein L53 2 74471958-74473322 Predicted intracellular proteins Evidence at protein level HPA056185 Uncertain Renal cancer:1.16e-8 (unfavourable), Liver cancer:7.36e-5 (unfavourable), Pancreatic cancer:1.37e-4 (favourable) Expressed in all Expressed in all lymph node: 25.0 MRPL54 ENSG00000183617 Mitochondrial ribosomal protein L54 19 3762664-3768575 Predicted intracellular proteins Evidence at protein level HPA042117, HPA046767 Uncertain Approved Mitochondria Expressed in all Expressed in all thyroid gland: 89.8 MRPL55 ENSG00000162910 Mitochondrial ribosomal protein L55 1 228106679-228109312 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027641 Approved Renal cancer:1.62e-6 (unfavourable), Ovarian cancer:6.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 41.0 MRPL57 MRP63 ENSG00000173141 Mitochondrial ribosomal protein L57 13 21176645-21179084 Predicted intracellular proteins Evidence at protein level HPA039779, HPA059370 Supported Supported Mitochondria Pancreatic cancer:8.35e-4 (favourable) Expressed in all Expressed in all adrenal gland: 21.9 MRPL9 ENSG00000143436 Mitochondrial ribosomal protein L9 1 151759643-151763564 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA008579 Approved Supported Mitochondria Liver cancer:1.04e-7 (unfavourable), Renal cancer:1.44e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.4 MRPS10 FLJ10567 ENSG00000048544 Mitochondrial ribosomal protein S10 6 42206801-42217865 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029133, HPA029134 Supported Approved Actin filaments
Mitochondria Expressed in all Expressed in all esophagus: 42.0 MRPS11 FLJ22512, FLJ23406, HCC-2 ENSG00000181991 Mitochondrial ribosomal protein S11 15 88467453-88480773 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043752, HPA050345 Supported Supported Mitochondria Cervical cancer:3.60e-4 (favourable), Ovarian cancer:4.75e-4 (favourable) Expressed in all Expressed in all thyroid gland: 13.5 MRPS12 RPMS12, RPS12, RPSM12 ENSG00000128626 Mitochondrial ribosomal protein S12 19 38930548-38933162 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046775, HPA050633 Uncertain Expressed in all Expressed in all duodenum: 12.3 MRPS14 HSMRPS14 ENSG00000120333 Mitochondrial ribosomal protein S14 1 175010789-175023425 Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA051087 Uncertain Supported Nuclear membrane
Mitochondria Expressed in all Expressed in all thyroid gland: 38.8 MRPS15 FLJ11564 ENSG00000116898 Mitochondrial ribosomal protein S15 1 36455718-36464437 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA028100, HPA028134, HPA067137 Supported Supported Mitochondria Renal cancer:3.55e-4 (unfavourable), Liver cancer:3.59e-4 (unfavourable), Ovarian cancer:7.83e-4 (favourable) Expressed in all Expressed in all testis: 241.1 MRPS16 CGI-132 ENSG00000182180 Mitochondrial ribosomal protein S16 10 73248843-73252693 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050081, HPA054538 Supported Supported Mitochondria
Cytosol Liver cancer:4.57e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.5 MRPS17 HSPC011, MRP-S17, RPMS17 ENSG00000239789 Mitochondrial ribosomal protein S17 7 55951819-55956501 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047159 Approved Expressed in all Expressed in all fallopian tube: 16.1 MRPS18A FLJ10548, MRPS18-3 ENSG00000096080 Mitochondrial ribosomal protein S18A 6 43671303-43687791 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA035450, HPA035451 Approved Thyroid cancer:4.03e-5 (favourable) Expressed in all Expressed in all prostate: 60.4 MRPS18B C6orf14, HSPC183, MRPS18-2, PTD017 ENSG00000204568 Mitochondrial ribosomal protein S18B 6 30617709-30626395 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043485, HPA050334 Supported Supported Cell Junctions
Mitochondria Renal cancer:3.99e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 13.2 MRPS18C CGI-134, FLJ11146, FLJ22967, MRPS18-1 ENSG00000163319 Mitochondrial ribosomal protein S18C 4 83455932-83469735 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050404 Approved Renal cancer:2.90e-5 (favourable) Expressed in all Expressed in all adrenal gland: 38.9 MRPS2 CGI-91 ENSG00000122140 Mitochondrial ribosomal protein S2 9 135499984-135504673 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029487, HPA057261 Approved Supported Mitochondria Renal cancer:6.96e-9 (favourable) Expressed in all Expressed in all fallopian tube: 54.4 MRPS21 ENSG00000266472 Mitochondrial ribosomal protein S21 1 150293720-150308979 Predicted intracellular proteins Evidence at protein level HPA078289 Approved Mitochondria Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 74.2 MRPS22 C3orf5, GIBT, GK002, MRP-S22 ENSG00000175110 Mitochondrial ribosomal protein S22 3 139005806-139357223 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006083, HPA007830 Supported Supported Mitochondria Endometrial cancer:1.35e-5 (unfavourable), Pancreatic cancer:1.55e-5 (unfavourable), Prostate cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 69.8 MRPS23 CGI-138, HSPC329, MRP-S23 ENSG00000181610 Mitochondrial ribosomal protein S23 17 57834781-57850056 Predicted intracellular proteins Evidence at protein level HPA023453 Supported Supported Nuclear membrane
Mitochondria Liver cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.2 MRPS24 HSPC335, MRP-S24 ENSG00000062582 Mitochondrial ribosomal protein S24 7 43866558-43869893 Predicted intracellular proteins Evidence at protein level HPA020983 Uncertain Lung cancer:1.91e-4 (unfavourable), Renal cancer:9.89e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 147.5 MRPS25 DKFZp313H0817, FLJ00023, MRP-S25, RPMS25 ENSG00000131368 Mitochondrial ribosomal protein S25 3 15042460-15065335 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043490 Approved Validated Mitochondria Renal cancer:3.60e-7 (favourable) Expressed in all Expressed in all testis: 33.1 MRPS26 C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13 ENSG00000125901 Mitochondrial ribosomal protein S26 20 3045945-3048254 Predicted intracellular proteins Evidence at protein level HPA045472, HPA054610 Supported Validated Mitochondria Expressed in all Expressed in all prostate: 49.1 MRPS27 KIAA0264 ENSG00000113048 Mitochondrial ribosomal protein S27 5 72219409-72320646 Predicted intracellular proteins Evidence at protein level HPA071751 Approved Expressed in all Expressed in all thyroid gland: 59.3 MRPS28 HSPC007, MRP-S28, MRPS35 ENSG00000147586 Mitochondrial ribosomal protein S28 8 79918717-80030289 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027202 Approved Validated Mitochondria Renal cancer:1.20e-6 (favourable) Expressed in all Expressed in all adrenal gland: 114.6 MRPS30 PAP, PDCD9 ENSG00000112996 Mitochondrial ribosomal protein S30 5 44808925-44820428 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA018686, HPA021149 Supported Renal cancer:2.87e-9 (favourable), Liver cancer:5.91e-4 (unfavourable) Expressed in all Expressed in all breast: 23.5 MRPS31 IMOGN38 ENSG00000102738 Mitochondrial ribosomal protein S31 13 40729135-40771173 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039083, HPA046344 Uncertain Supported Nucleoli
Mitochondria Expressed in all Expressed in all testis,thyroid gland: 33.4 MRPS33 CGI-139 ENSG00000090263 Mitochondrial ribosomal protein S33 7 141002610-141015228 Predicted intracellular proteins Evidence at protein level HPA030425 Uncertain Expressed in all Expressed in all epididymis: 94.6 MRPS34 MGC2616, MRP-S12 ENSG00000074071 Mitochondrial ribosomal protein S34 16 1771890-1773155 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042112 Supported Supported Mitochondria Expressed in all Expressed in all spleen: 22.6 MRPS35 MDS023, MRPS28 ENSG00000061794 Mitochondrial ribosomal protein S35 12 27710773-27756295 Predicted intracellular proteins Evidence at protein level HPA038513 Supported Approved Mitochondria
Cytosol Renal cancer:1.51e-5 (favourable), Liver cancer:1.64e-4 (unfavourable), Colorectal cancer:5.01e-4 (favourable), Breast cancer:9.41e-4 (unfavourable) Expressed in all Expressed in all kidney: 78.1 MRPS36 DC47, MRP-S36 ENSG00000134056 Mitochondrial ribosomal protein S36 5 69217760-69230129 Predicted intracellular proteins Evidence at protein level HPA035802, HPA056795 Supported Validated Mitochondria Renal cancer:5.02e-6 (favourable) Expressed in all Expressed in all kidney: 51.8 MRPS5 MRP-S5, S5mt ENSG00000144029 Mitochondrial ribosomal protein S5 2 95087207-95149434 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055765 Approved Supported Mitochondria Endometrial cancer:7.98e-7 (unfavourable), Liver cancer:7.73e-5 (unfavourable), Thyroid cancer:6.36e-4 (favourable) Expressed in all Expressed in all kidney: 37.4 MRPS6 C21orf101, MRP-S6, RPMS6 ENSG00000243927 Mitochondrial ribosomal protein S6 21 34073224-34143034 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA007861, HPA008163, HPA049676 Supported Supported Mitochondria Urothelial cancer:1.06e-5 (favourable) Expressed in all Expressed in all thyroid gland: 120.5 MRPS7 MRP-S, RP-S7, RPMS7 ENSG00000125445 Mitochondrial ribosomal protein S7 17 75261674-75266373 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA022522, HPA023007 Supported Approved Mitochondria Colorectal cancer:1.12e-4 (favourable), Liver cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 59.3 MRPS9 MRP-S9, RPMS9, S9mt ENSG00000135972 Mitochondrial ribosomal protein S9 2 105037983-105099960 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043476, HPA048479 Supported Validated Nucleoli
Mitochondria Liver cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all testis: 57.6 MRRF RRF ENSG00000148187 Mitochondrial ribosome recycling factor 9 122264603-122331343 Predicted intracellular proteins Evidence at protein level HPA047177, HPA049987 Supported Approved Microtubules
Cytokinetic bridge Renal cancer:2.14e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 33.9 MRS2 MRS2L ENSG00000124532 MRS2 magnesium transporter 6 24402908-24426194 Predicted membrane proteins Evidence at protein level HPA017642 Uncertain Ovarian cancer:5.14e-11 (favourable), Endometrial cancer:5.32e-4 (unfavourable), Thyroid cancer:8.03e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 29.8 MRTO4 C1orf33, dJ657E11.4, MRT4 ENSG00000053372 MRT4 homolog, ribosome maturation factor 1 19251539-19260128 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA026446 Approved Approved Nucleus
Nuclear membrane
Nucleoli Liver cancer:1.56e-8 (unfavourable), Renal cancer:4.11e-8 (unfavourable) Expressed in all Expressed in all fallopian tube: 26.0 MS4A6A CD20L3, MS4A6 ENSG00000110077 Membrane-spanning 4-domains, subfamily A, member 6A 11 60172014-60184666 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA011391, HPA076623 Approved Approved Vesicles Cervical cancer:6.33e-4 (favourable) Expressed in all Expressed in all lymph node: 115.2 MSANTD3 C9orf30, MGC17337 ENSG00000066697 Myb/SANT-like DNA-binding domain containing 3 9 100427156-100451711 Predicted intracellular proteins Evidence at protein level HPA062662 Approved Nucleoplasm Renal cancer:3.22e-7 (unfavourable), Liver cancer:3.23e-6 (unfavourable), Head and neck cancer:6.66e-5 (unfavourable), Lung cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 23.5 MSANTD4 KIAA1826 ENSG00000170903 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 11 105995623-106022403 Predicted intracellular proteins Evidence at protein level HPA014411 Approved Approved Nucleus Renal cancer:1.26e-5 (favourable), Breast cancer:4.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 27.5 MSH2 COCA1, HNPCC, HNPCC1 ENSG00000095002 MutS homolog 2 2 47402969-47562311 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009572, CAB070867 Supported Approved Nucleoplasm
Vesicles Liver cancer:1.72e-9 (unfavourable), Endometrial cancer:4.44e-4 (unfavourable), Pancreatic cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 32.6 MSH3 DUP, MRP1 ENSG00000113318 MutS homolog 3 5 80654648-80876460 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA036081 Approved Nuclear bodies Colorectal cancer:5.90e-5 (favourable), Renal cancer:1.77e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.6 MSH6 GTBP ENSG00000116062 MutS homolog 6 2 47695530-47810101 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009091, HPA028376, HPA028446 Supported Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:1.06e-7 (unfavourable), Endometrial cancer:1.34e-4 (unfavourable), Liver cancer:7.86e-4 (unfavourable) Expressed in all Expressed in all ovary: 74.4 MSI2 ENSG00000153944 Musashi RNA-binding protein 2 17 57255851-57684685 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB022300 Approved Supported Cytosol Renal cancer:9.22e-8 (favourable), Stomach cancer:2.00e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 117.6 MSL1 DKFZp686P24239, hMSL1, MSL-1 ENSG00000188895 Male-specific lethal 1 homolog (Drosophila) 17 40122298-40136916 Predicted intracellular proteins Evidence at protein level HPA022800, HPA023567 Uncertain Validated Nucleoplasm Renal cancer:3.06e-6 (unfavourable) Expressed in all Expressed in all testis: 106.7 MSL2 FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184 ENSG00000174579 Male-specific lethal 2 homolog (Drosophila) 3 136148922-136197241 Predicted intracellular proteins Evidence at protein level HPA003413, HPA048482 Uncertain Approved Cytosol Cervical cancer:4.80e-4 (favourable) Expressed in all Expressed in all lymph node: 40.4 MSL3 MSL3L1 ENSG00000005302 Male-specific lethal 3 homolog (Drosophila) X 11758159-11775753 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034535, HPA034536 Uncertain Approved Nucleoplasm Renal cancer:3.14e-9 (unfavourable), Urothelial cancer:2.17e-4 (favourable), Head and neck cancer:3.28e-4 (favourable), Liver cancer:4.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 60.6 MSMO1 DESP4, ERG25, SC4MOL ENSG00000052802 Methylsterol monooxygenase 1 4 165327623-165343160 Enzymes, Predicted membrane proteins Evidence at protein level HPA056127 Approved Cervical cancer:2.97e-4 (unfavourable), Renal cancer:9.21e-4 (favourable) Expressed in all Expressed in all liver: 296.4 MSN ENSG00000147065 Moesin X 65588377-65741931 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047338 Supported Validated Plasma membrane Renal cancer:1.60e-5 (unfavourable) Expressed in all Expressed in all lung: 421.4 MSRA ENSG00000175806 Methionine sulfoxide reductase A 8 10054268-10428891 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023804, HPA053069 Approved Validated Nucleoplasm
Cytosol Expressed in all Expressed in all kidney: 112.4 MSRB1 SelR, SelX, SepR, SEPX1 ENSG00000198736 Methionine sulfoxide reductase B1 16 1938210-1943326 Predicted intracellular proteins Evidence at protein level CAB008650, HPA043463, HPA069557 Approved Validated Nucleoplasm Expressed in all Expressed in all liver: 61.6 MSRB3 DFNB74, DKFZp686C1178, FLJ36866 ENSG00000174099 Methionine sulfoxide reductase B3 12 65278643-65488244 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA014432 Uncertain Renal cancer:8.85e-8 (unfavourable), Urothelial cancer:2.17e-4 (unfavourable), Cervical cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 179.8 MT-ATP6 ATP6, ATPase-6, MTATP6, RP, Su6m ENSG00000198899 Mitochondrially encoded ATP synthase 6 MT 8527-9207 Disease related genes, Predicted membrane proteins Evidence at protein level Liver cancer:3.79e-4 (favourable), Pancreatic cancer:7.64e-4 (favourable) Expressed in all Expressed in all heart muscle: 40782.8 MT-ATP8 A6L, ATP8, MTATP8 ENSG00000228253 Mitochondrially encoded ATP synthase 8 MT 8366-8572 Disease related genes, Predicted membrane proteins Evidence at protein level Liver cancer:7.56e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 66430.7 MT-CO1 COI, COX1, MTCO1 ENSG00000198804 Mitochondrially encoded cytochrome c oxidase I MT 5904-7445 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB016241, HPA069328 Supported Supported Mitochondria Liver cancer:2.29e-4 (favourable) Expressed in all Expressed in all heart muscle: 79793.3 MT-CO2 CO2, COX2, MTCO2 ENSG00000198712 Mitochondrially encoded cytochrome c oxidase II MT 7586-8269 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB016243, HPA051505, HPA054758 Supported Liver cancer:2.89e-4 (favourable), Pancreatic cancer:7.10e-4 (favourable) Expressed in all Expressed in all heart muscle: 42147.3 MT-CO3 CO3, COIII, COX3, MTCO3 ENSG00000198938 Mitochondrially encoded cytochrome c oxidase III MT 9207-9990 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042788 Approved Approved Nucleoplasm Pancreatic cancer:1.04e-4 (favourable), Liver cancer:2.01e-4 (favourable) Expressed in all Expressed in all heart muscle: 56545.8 MT-CYB COB, CYTB, MTCYB, UQCR3 ENSG00000198727 Mitochondrially encoded cytochrome b MT 14747-15887 Disease related genes, Predicted membrane proteins Evidence at protein level CAB032215, HPA068400 Approved Approved Mitochondria Liver cancer:5.96e-4 (favourable) Expressed in all Expressed in all heart muscle: 24037.9 MT-ND1 MTND1, NAD1, ND1 ENSG00000198888 Mitochondrially encoded NADH dehydrogenase 1 MT 3307-4262 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB033779 Approved Pancreatic cancer:3.26e-4 (favourable), Breast cancer:3.63e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 23823.0 MT-ND2 MTND2, NAD2, ND2 ENSG00000198763 Mitochondrially encoded NADH dehydrogenase 2 MT 4470-5511 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all heart muscle: 25403.8 MT-ND3 MTND3, NAD3, ND3 ENSG00000198840 Mitochondrially encoded NADH dehydrogenase 3 MT 10059-10404 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA063296 Supported Approved Cytosol Liver cancer:4.63e-5 (favourable) Expressed in all Expressed in all heart muscle: 30137.8 MT-ND4 LHON, MTND4, NAD4, ND4 ENSG00000198886 Mitochondrially encoded NADH dehydrogenase 4 MT 10760-12137 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA053928 Approved Ovarian cancer:1.76e-4 (favourable) Expressed in all Expressed in all heart muscle: 38133.1 MT-ND4L MTND4L, NAD4L, ND4L ENSG00000212907 Mitochondrially encoded NADH dehydrogenase 4L MT 10470-10766 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA075648 Approved Mitochondria Liver cancer:4.47e-4 (favourable) Expressed in all Expressed in all heart muscle: 23512.4 MT-ND5 MTND5, NAD5, ND5 ENSG00000198786 Mitochondrially encoded NADH dehydrogenase 5 MT 12337-14148 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Renal cancer:7.31e-5 (favourable) Expressed in all Expressed in all heart muscle: 13033.0 MT-ND6 MTND6, NAD6, ND6 ENSG00000198695 Mitochondrially encoded NADH dehydrogenase 6 MT 14149-14673 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level Renal cancer:8.91e-6 (favourable) Expressed in all Expressed in all heart muscle: 21512.1 MT1E MT1, MTD ENSG00000169715 Metallothionein 1E 16 56625475-56627112 Predicted intracellular proteins Evidence at protein level Renal cancer:5.06e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 418.9 MT1X MT-1l, MT1 ENSG00000187193 Metallothionein 1X 16 56682424-56684196 Predicted intracellular proteins Evidence at protein level Renal cancer:1.82e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 1345.5 MT2A MT2 ENSG00000125148 Metallothionein 2A 16 56608199-56609497 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:2.92e-9 (unfavourable), Lung cancer:5.74e-5 (unfavourable), Pancreatic cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 1206.6 MTA1 ENSG00000182979 Metastasis associated 1 14 105419820-105470729 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004508, HPA005544 Supported Validated Nucleoplasm
Cytosol Pancreatic cancer:9.48e-5 (favourable), Liver cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all testis: 35.8 MTA2 MTA1-L1, MTA1L1 ENSG00000149480 Metastasis associated 1 family, member 2 11 62593214-62601840 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005315, HPA006214, CAB017522 Supported Validated Nucleoplasm Liver cancer:4.82e-5 (unfavourable) Expressed in all Expressed in all skin: 88.6 MTA3 KIAA1266 ENSG00000057935 Metastasis associated 1 family, member 3 2 42494569-42756947 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039433 Approved Supported Nucleus
Vesicles Endometrial cancer:2.30e-4 (unfavourable), Liver cancer:4.69e-4 (unfavourable) Expressed in all Expressed in all testis: 52.2 MTAP c86fus, MSAP ENSG00000099810 Methylthioadenosine phosphorylase 9 21802543-21937651 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046915 Supported Cytosol Liver cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 16.1 MTCH1 CGI-64, PSAP, SLC25A49 ENSG00000137409 Mitochondrial carrier 1 6 36968141-36986298 Predicted membrane proteins, Transporters Evidence at protein level HPA015971 Approved Renal cancer:1.16e-7 (favourable), Liver cancer:1.17e-4 (unfavourable), Endometrial cancer:2.06e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 568.7 MTCH2 SLC25A50 ENSG00000109919 Mitochondrial carrier 2 11 47617315-47642623 Predicted membrane proteins, Transporters Evidence at protein level HPA038390 Approved Supported Mitochondria Renal cancer:9.05e-6 (favourable) Expressed in all Expressed in all testis: 137.7 MTDH 3D3, AEG-1, LYRIC ENSG00000147649 Metadherin 8 97644179-97728770 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010932, HPA015104, CAB068204, CAB068205 Supported Validated Endoplasmic reticulum Renal cancer:3.82e-4 (unfavourable), Pancreatic cancer:5.36e-4 (unfavourable), Lung cancer:7.76e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 104.0 MTERF1 MTERF ENSG00000127989 Mitochondrial transcription termination factor 1 7 91692008-91880720 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044894, HPA069560 Uncertain Supported Mitochondria Expressed in all Expressed in all lymph node: 16.6 MTERF2 FLJ14062, MTERFD3 ENSG00000120832 Mitochondrial transcription termination factor 2 12 106977291-106987166 Predicted intracellular proteins Evidence at protein level HPA003526 Approved Cervical cancer:8.50e-4 (favourable) Expressed in all Expressed in all adrenal gland: 29.3 MTERF3 CGI-12, FLJ10939, MTERFD1 ENSG00000156469 Mitochondrial transcription termination factor 3 8 96239398-96261610 Predicted intracellular proteins Evidence at protein level HPA002966 Supported Nucleoplasm
Mitochondria Renal cancer:5.88e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.8 MTERF4 MGC61716, MTERFD2 ENSG00000122085 Mitochondrial transcription termination factor 4 2 241072169-241102332 Predicted intracellular proteins Evidence at protein level HPA027097 Uncertain Supported Mitochondria
Cytosol Pancreatic cancer:3.48e-4 (favourable) Expressed in all Expressed in all thyroid gland: 58.8 MTFP1 HSPC242, MTP18 ENSG00000242114 Mitochondrial fission process 1 22 30425530-30429053 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA077396 Approved Mitochondria Expressed in all Expressed in all epididymis: 18.7 MTFR1 CHPPR, FAM54A2, KIAA0009 ENSG00000066855 Mitochondrial fission regulator 1 8 65644734-65771261 Predicted intracellular proteins Evidence at protein level HPA023152, HPA056120 Uncertain Supported Mitochondria
Cytosol Breast cancer:4.06e-4 (unfavourable), Thyroid cancer:5.21e-4 (unfavourable) Expressed in all Expressed in all testis: 34.9 MTFR1L FAM54B ENSG00000117640 Mitochondrial fission regulator 1-like 1 25818640-25832942 Predicted intracellular proteins Evidence at protein level HPA027124, HPA027130 Approved Approved Cell Junctions
Mitochondria Renal cancer:5.89e-12 (favourable), Endometrial cancer:6.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 155.3 MTG1 GTPBP7 ENSG00000148824 Mitochondrial ribosome-associated GTPase 1 10 133394094-133421307 Predicted intracellular proteins Evidence at protein level HPA037826, HPA037827 Approved Supported Mitochondria Renal cancer:6.79e-7 (unfavourable), Urothelial cancer:1.03e-5 (favourable), Pancreatic cancer:5.08e-4 (favourable) Expressed in all Expressed in all testis: 29.4 MTG2 dJ1005F21.2, FLJ10741, GTPBP5, ObgH1 ENSG00000101181 Mitochondrial ribosome-associated GTPase 2 20 62183029-62203568 Predicted intracellular proteins Evidence at protein level HPA047379 Approved Pancreatic cancer:6.31e-5 (favourable) Expressed in all Expressed in all adrenal gland: 15.9 MTHFD1 MTHFC, MTHFD ENSG00000100714 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 14 64388031-64463457 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000704, HPA001290, HPA015006, HPA050052 Approved Validated Cytosol Renal cancer:5.93e-5 (favourable), Pancreatic cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all liver: 198.3 MTHFD2 ENSG00000065911 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 74198562-74217565 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB003684, HPA049657 Approved Renal cancer:1.11e-16 (unfavourable), Endometrial cancer:2.07e-5 (unfavourable), Glioma:8.47e-5 (favourable) Expressed in all Expressed in all appendix: 40.7 MTHFR ENSG00000177000 Methylenetetrahydrofolate reductase (NAD(P)H) 1 11785723-11806920 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA063389 Approved Cell Junctions Head and neck cancer:3.97e-5 (favourable), Pancreatic cancer:4.81e-5 (favourable), Liver cancer:1.19e-4 (unfavourable), Renal cancer:2.12e-4 (favourable) Expressed in all Expressed in all epididymis: 65.3 MTHFS HsT19268 ENSG00000136371 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) 15 79833585-79897379 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008067, HPA054177 Approved Supported Cytosol Liver cancer:1.29e-6 (favourable), Renal cancer:2.04e-4 (favourable), Glioma:6.94e-4 (unfavourable) Expressed in all Expressed in all liver: 115.9 MTHFSD FLJ12998 ENSG00000103248 Methenyltetrahydrofolate synthetase domain containing 16 86530176-86555235 Predicted intracellular proteins Evidence at protein level HPA041333 Uncertain Approved Nucleus
Vesicles Colorectal cancer:9.88e-5 (unfavourable) Expressed in all Expressed in all testis: 33.1 MTIF2 IF-2mt ENSG00000085760 Mitochondrial translational initiation factor 2 2 55236595-55269347 Predicted intracellular proteins Evidence at protein level HPA006021, HPA061422 Uncertain Validated Mitochondria Expressed in all Expressed in all parathyroid gland: 39.8 MTIF3 IF-3mt, IF3(mt) ENSG00000122033 Mitochondrial translational initiation factor 3 13 27435643-27450591 Predicted intracellular proteins Evidence at protein level HPA039791 Approved Supported Nucleoplasm
Mitochondria Urothelial cancer:8.41e-4 (favourable) Expressed in all Expressed in all testis: 100.8 MTMR1 ENSG00000063601 Myotubularin related protein 1 X 150692971-150765103 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002977, HPA018502 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Expressed in all Expressed in all parathyroid gland: 26.3 MTMR10 FLJ20313 ENSG00000166912 Myotubularin related protein 10 15 30938941-30991607 Predicted intracellular proteins Evidence at protein level HPA006081 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:7.77e-12 (favourable) Expressed in all Expressed in all placenta: 35.5 MTMR12 3-PAP, 3PAP, FLJ20476, KIAA1682, PIP3AP ENSG00000150712 Myotubularin related protein 12 5 32226994-32313009 Predicted intracellular proteins Evidence at protein level HPA051333 Supported Renal cancer:1.29e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 41.8 MTMR14 C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy ENSG00000163719 Myotubularin related protein 14 3 9649433-9702394 Disease related genes, Predicted secreted proteins Evidence at protein level HPA054063 Approved Renal cancer:2.74e-4 (favourable), Liver cancer:3.95e-4 (unfavourable) Expressed in all Expressed in all lymph node: 42.4 MTMR2 CMT4B, KIAA1073 ENSG00000087053 Myotubularin related protein 2 11 95832882-95925315 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA049831 Approved Supported Vesicles Liver cancer:1.61e-8 (unfavourable), Pancreatic cancer:3.60e-4 (unfavourable) Expressed in all Expressed in all testis: 57.6 MTMR3 FYVE-DSP1, KIAA0371, ZFYVE10 ENSG00000100330 Myotubularin related protein 3 22 29883155-30030866 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034515, HPA034516, HPA061399 Uncertain Supported Nucleoplasm
Cytosol Mixed Expressed in all bone marrow: 52.4 MTMR4 KIAA0647, ZFYVE11 ENSG00000108389 Myotubularin related protein 4 17 58489529-58517905 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:1.53e-5 (unfavourable), Pancreatic cancer:5.09e-4 (favourable) Expressed in all Expressed in all testis: 35.5 MTMR6 ENSG00000139505 Myotubularin related protein 6 13 25246201-25288009 Plasma proteins, Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all testis: 30.5 MTO1 ENSG00000135297 Mitochondrial tRNA translation optimization 1 6 73461578-73509236 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030230, HPA030232 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 24.8 MTOR FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 ENSG00000198793 Mechanistic target of rapamycin (serine/threonine kinase) 1 11106535-11262507 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB069425, HPA071227 Approved Approved Vesicles
Cytosol Renal cancer:1.49e-5 (favourable) Expressed in all Expressed in all testis: 62.0 MTPAP FLJ10486, mtPAP, PAPD1, SPAX4 ENSG00000107951 Mitochondrial poly(A) polymerase 10 30309801-30374448 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038620, HPA058232 Approved Supported Mitochondria Liver cancer:4.20e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 22.7 MTPN GCDP, MYOTROPHIN, V-1 ENSG00000105887 Myotrophin 7 135926761-135977353 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019735 Approved Approved Plasma membrane
Cytosol Liver cancer:1.19e-4 (unfavourable), Pancreatic cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 194.2 MTR cblG ENSG00000116984 5-methyltetrahydrofolate-homocysteine methyltransferase 1 236795281-236903981 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA044474 Supported Cytosol Thyroid cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.4 MTRF1 MGC47721, MTTRF1, RF1 ENSG00000120662 Mitochondrial translational release factor 1 13 41216369-41263577 Predicted intracellular proteins Evidence at protein level HPA043316 Uncertain Expressed in all Expressed in all testis: 25.1 MTRF1L ENSG00000112031 Mitochondrial translational release factor 1-like 6 152987362-153002685 Predicted intracellular proteins Evidence at protein level HPA036367 Uncertain Breast cancer:4.82e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 13.2 MTRNR2L1 ENSG00000256618 MT-RNR2-like 1 17 22523111-22524663 Predicted intracellular proteins Evidence at transcript level Liver cancer:8.99e-4 (favourable) Expressed in all Expressed in all heart muscle: 1053.3 MTRNR2L11 ENSG00000270188 MT-RNR2-like 11 (pseudogene) 1 237943724-237945275 Predicted secreted proteins Evidence at transcript level Not detected Expressed in all skeletal muscle: 113.5 MTRNR2L12 ENSG00000269028 MT-RNR2-like 12 3 96617188-96618236 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all heart muscle: 14876.2 MTRNR2L4 ENSG00000232196 MT-RNR2-like 4 16 3370979-3372740 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all skeletal muscle: 98.2 MTRNR2L6 ENSG00000270672 MT-RNR2-like 6 7 142666272-142667718 Predicted intracellular proteins Evidence at transcript level Mixed Expressed in all skeletal muscle: 131.8 MTRNR2L8 ENSG00000255823 MT-RNR2-like 8 11 10507887-10509189 Predicted intracellular proteins Evidence at transcript level Mixed Expressed in all heart muscle: 1840.4 MTRR cblE ENSG00000124275 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 5 7851186-7906025 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038113 Supported Approved Nucleoplasm
Intermediate filaments
Cytosol Liver cancer:6.60e-4 (unfavourable) Expressed in all Expressed in all kidney: 20.4 MTSS1 KIAA0429, MIM, MIMA, MIMB ENSG00000170873 Metastasis suppressor 1 8 124550790-124728429 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA075540 Approved Renal cancer:2.11e-7 (favourable) Expressed in all Expressed in all placenta: 51.4 MTSS1L ABBA-1, LOC92154 ENSG00000132613 Metastasis suppressor 1-like 16 70661204-70686066 Predicted intracellular proteins Evidence at protein level HPA048531, HPA066469 Approved Supported Focal adhesion sites Breast cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 320.9 MTURN C7orf41, Ells1, FLJ25903 ENSG00000180354 Maturin, neural progenitor differentiation regulator homolog (Xenopus) 7 30134810-30162762 Predicted intracellular proteins Evidence at protein level HPA029507 Approved Approved Cytosol Renal cancer:7.64e-13 (favourable) Expressed in all Expressed in all cerebral cortex: 352.3 MTX1 MTX, MTXN ENSG00000173171 Metaxin 1 1 155208699-155213824 Predicted membrane proteins Evidence at protein level HPA011543 Uncertain Supported Mitochondria Renal cancer:3.39e-4 (unfavourable) Expressed in all Expressed in all testis: 71.3 MTX2 ENSG00000128654 Metaxin 2 2 176269395-176338025 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA031550, HPA031551, HPA031552 Approved Approved Supported Nucleoli
Mitochondria Endometrial cancer:5.06e-4 (unfavourable) Expressed in all Expressed in all testis: 115.8 MTX3 ENSG00000177034 Metaxin 3 5 79976731-79991262 Predicted intracellular proteins Evidence at protein level HPA047858, HPA062061 Approved Approved Mitochondria Liver cancer:5.08e-5 (unfavourable), Ovarian cancer:2.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.2 MUL1 C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218 ENSG00000090432 Mitochondrial E3 ubiquitin protein ligase 1 1 20499448-20508161 Predicted membrane proteins Evidence at protein level HPA026827 Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:6.15e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 39.0 MUM1 EXPAND1, MUM-1 ENSG00000160953 Melanoma associated antigen (mutated) 1 19 1285893-1378431 Predicted intracellular proteins Evidence at protein level HPA048063 Uncertain Approved Nucleus
Cytosol Pancreatic cancer:2.25e-6 (favourable), Endometrial cancer:4.82e-4 (favourable) Expressed in all Expressed in all testis: 60.9 MUS81 FLJ44872, SLX3 ENSG00000172732 MUS81 structure-specific endonuclease subunit 11 65857126-65867653 Predicted intracellular proteins Evidence at protein level HPA059530 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:6.05e-4 (unfavourable) Expressed in all Expressed in all endometrium: 25.2 MUT ENSG00000146085 Methylmalonyl CoA mutase 6 49430360-49463191 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035971, HPA035972 Supported Approved Mitochondria
Cytosol Renal cancer:8.71e-13 (favourable) Expressed in all Expressed in all liver: 104.1 MVB12A FAM125A, FLJ32495 ENSG00000141971 Multivesicular body subunit 12A 19 17405722-17433724 Predicted intracellular proteins Evidence at protein level HPA041885, HPA042231 Approved Supported Nucleoplasm
Golgi apparatus Cervical cancer:3.26e-4 (favourable) Expressed in all Expressed in all ovary: 38.0 MVD MPD ENSG00000167508 Mevalonate (diphospho) decarboxylase 16 88651935-88663161 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041404, HPA048250 Uncertain Approved Cell Junctions
Cytosol Endometrial cancer:2.17e-4 (favourable) Expressed in all Expressed in all duodenum: 34.8 MVK LRBP, MK ENSG00000110921 Mevalonate kinase 12 109573255-109598117 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016961 Approved Expressed in all Expressed in all testis: 29.5 MVP LRP, VAULT1 ENSG00000013364 Major vault protein 16 29820394-29848039 Cancer-related genes, Predicted intracellular proteins, Transporters Evidence at protein level HPA002321, CAB002752, CAB022717, HPA064740 Supported Validated Cytosol Renal cancer:5.49e-5 (favourable), Breast cancer:4.51e-4 (favourable) Expressed in all Expressed in all small intestine: 169.1 MX1 IFI-78K, MxA ENSG00000157601 MX dynamin-like GTPase 1 21 41420304-41459214 Predicted intracellular proteins Evidence at protein level HPA030917, HPA030918, HPA049724 Approved Approved Supported Nuclear membrane
Cytosol Renal cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 120.4 MXD4 bHLHc12, MAD4, MST149, MSTP149 ENSG00000123933 MAX dimerization protein 4 4 2247432-2262294 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053363 Supported Cytosol Pancreatic cancer:1.39e-5 (favourable), Head and neck cancer:2.21e-5 (favourable) Expressed in all Expressed in all spleen: 42.0 MXI1 bHLHc11, MAD2, MXD2, MXI ENSG00000119950 MAX interactor 1, dimerization protein 10 110207605-110287365 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035319, HPA056762 Approved Supported Nucleus
Nucleoli Renal cancer:1.02e-5 (unfavourable), Prostate cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 88.4 MXRA7 FLJ46603, PS1TP1, TMAP1 ENSG00000182534 Matrix-remodelling associated 7 17 76672551-76711016 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044819 Uncertain Approved Nucleus
Endoplasmic reticulum Urothelial cancer:1.80e-5 (unfavourable), Liver cancer:4.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 454.2 MYADM ENSG00000179820 Myeloid-associated differentiation marker 19 53866223-53876437 Predicted membrane proteins, Transporters Evidence at protein level HPA056301 Approved Nuclear speckles Renal cancer:7.71e-7 (unfavourable), Lung cancer:8.15e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 257.6 MYBBP1A FLJ37886, P160, PAP2 ENSG00000132382 MYB binding protein (P160) 1a 17 4538897-4555631 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005466 Supported Supported Nucleoli
Vesicles Pancreatic cancer:1.61e-4 (favourable), Renal cancer:5.95e-4 (unfavourable), Thyroid cancer:8.12e-4 (unfavourable), Melanoma:8.47e-4 (unfavourable) Expressed in all Expressed in all skin: 21.7 MYC bHLHe39, c-Myc, MYCC ENSG00000136997 V-myc avian myelocytomatosis viral oncogene homolog 8 127735434-127741434 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000084, CAB010307, HPA055893, HPA066556 Supported Validated Nucleoplasm Renal cancer:5.49e-8 (unfavourable), Urothelial cancer:4.96e-5 (unfavourable), Ovarian cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 144.4 MYCBP AMY-1 ENSG00000214114 MYC binding protein 1 38862964-38874105 Predicted intracellular proteins Evidence at protein level HPA041188, HPA078331 Supported Supported Mitochondria
Cytosol Liver cancer:6.03e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 38.6 MYCBP2 FLJ10106, KIAA0916, PAM ENSG00000005810 MYC binding protein 2, E3 ubiquitin protein ligase 13 77044655-77327050 Predicted intracellular proteins Evidence at protein level HPA039945 Uncertain Cytosol Renal cancer:5.01e-5 (favourable) Expressed in all Expressed in all skin: 82.8 MYDGF C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20 ENSG00000074842 Myeloid-derived growth factor 19 4641374-4670370 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041872, HPA046744 Approved Renal cancer:4.99e-12 (unfavourable), Endometrial cancer:6.50e-7 (favourable) Expressed in all Expressed in all epididymis: 132.3 MYEOV2 ENSG00000172428 Myeloma overexpressed 2 2 240126563-240136807 Predicted intracellular proteins Evidence at protein level HPA044845 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 192.6 MYH10 NMMHCB ENSG00000133026 Myosin, heavy chain 10, non-muscle 17 8474205-8630761 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017180, HPA047541, HPA057198 Supported Validated Actin filaments
Mitochondria
Cytosol Renal cancer:1.38e-4 (favourable), Urothelial cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all lung: 81.2 MYH9 DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA ENSG00000100345 Myosin, heavy chain 9, non-muscle 22 36281281-36388018 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001644, CAB015386 Supported Approved Plasma membrane
Actin filaments
Cytosol Expressed in all Expressed in all spleen: 313.7 MYL12A MLCB, MRCL3, MRLC3, MYL2B ENSG00000101608 Myosin, light chain 12A, regulatory, non-sarcomeric 18 3247481-3256236 Predicted intracellular proteins Evidence at protein level CAB004503, HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all heart muscle: 2307.5 MYL12B MRLC2 ENSG00000118680 Myosin, light chain 12B, regulatory 18 3261909-3278284 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Thyroid cancer:6.62e-6 (favourable), Renal cancer:8.17e-5 (favourable), Pancreatic cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all epididymis: 577.0 MYL5 ENSG00000215375 Myosin, light chain 5, regulatory 4 673580-682033 Predicted intracellular proteins Evidence at protein level HPA037381, HPA039262 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 30.3 MYL6 ESMLC, MLC1SM, MLC3NM ENSG00000092841 Myosin, light chain 6, alkali, smooth muscle and non-muscle 12 56158161-56163496 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046859, HPA063034 Approved Expressed in all Expressed in all smooth muscle: 5900.6 MYL6B MLC1SA ENSG00000196465 Myosin, light chain 6B, alkali, smooth muscle and non-muscle 12 56152256-56159647 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038887, HPA046859, HPA063034 Supported Approved Vesicles Liver cancer:2.87e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 149.7 MYL9 LC20, MLC2, MRLC1, MYRL2 ENSG00000101335 Myosin, light chain 9, regulatory 20 36541484-36551447 Predicted intracellular proteins Evidence at protein level HPA039262, HPA045244, HPA059197 Supported Approved Nucleus
Nucleoli fibrillar center Renal cancer:7.92e-7 (unfavourable) Expressed in all Expressed in all seminal vesicle: 3106.0 MYLIP IDOL, MIR ENSG00000007944 Myosin regulatory light chain interacting protein 6 16129125-16148248 Plasma proteins, Predicted intracellular proteins Evidence at protein level Lung cancer:6.44e-6 (favourable), Urothelial cancer:4.11e-5 (favourable), Renal cancer:3.67e-4 (favourable) Expressed in all Expressed in all placenta: 118.5 MYLK MLCK, MLCK1, MYLK1, smMLCK ENSG00000065534 Myosin light chain kinase 3 123610049-123884331 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB020789, HPA031677 Supported Supported Cytosol Renal cancer:2.04e-6 (unfavourable), Urothelial cancer:4.46e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 2971.5 MYNN SBBIZ1, ZBTB31, ZNF902 ENSG00000085274 Myoneurin 3 169772831-169789716 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045149 Approved Supported Nucleus Expressed in all Expressed in all testis: 18.2 MYO10 KIAA0799 ENSG00000145555 Myosin X 5 16661914-16936276 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015224, HPA024223 Supported Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:2.75e-4 (favourable), Cervical cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 68.5 MYO15B MYO15BP ENSG00000266714 Myosin XVB 17 75588058-75626501 Predicted intracellular proteins Evidence at transcript level HPA022857, HPA023105 Approved Cytosol Urothelial cancer:6.90e-5 (favourable), Breast cancer:9.34e-4 (favourable) Expressed in all Expressed in all duodenum: 152.7 MYO18A KIAA0216, MysPDZ ENSG00000196535 Myosin XVIIIA 17 29073517-29180412 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019646, HPA021121 Supported Renal cancer:3.18e-4 (favourable), Ovarian cancer:3.28e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 25.0 MYO19 FLJ22865, MYOHD1 ENSG00000278259 Myosin XIX 17 36495633-36543435 Predicted intracellular proteins Evidence at protein level HPA021415, HPA059715 Approved Validated Cytosol Liver cancer:8.33e-6 (unfavourable) Expressed in all Expressed in all skin: 14.5 MYO1C myr2 ENSG00000197879 Myosin IC 17 1464098-1492812 Predicted intracellular proteins, Transporters Evidence at protein level HPA001768, HPA005924, CAB037023 Supported Validated Nuclear bodies
Plasma membrane Lung cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 191.9 MYO1E HuncM-IC, MGC104638, MYO1C ENSG00000157483 Myosin IE 15 59132434-59372900 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023886 Approved Lung cancer:1.57e-6 (unfavourable), Endometrial cancer:4.19e-4 (favourable), Pancreatic cancer:7.99e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 66.8 MYO5A GS1, MYH12, MYO5, MYR12 ENSG00000197535 Myosin VA 15 52307283-52529050 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001356 Approved Approved Focal adhesion sites
Microtubule organizing center Urothelial cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 94.6 MYO9B CELIAC4 ENSG00000099331 Myosin IXB 19 17075781-17214537 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB037190, HPA042043 Approved Supported Cytosol Renal cancer:5.66e-6 (unfavourable), Ovarian cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all spleen: 100.6 MZF1 MZF-1, MZF1B, Zfp98, ZNF42, ZSCAN6 ENSG00000099326 Myeloid zinc finger 1 19 58561931-58573575 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001757 Approved Supported Nucleus Renal cancer:2.83e-8 (unfavourable), Urothelial cancer:4.09e-5 (favourable), Pancreatic cancer:7.97e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 14.7 MZT1 C13orf37, FLJ21869, LOC440145, MGC150539, MOZART1, RP11-11C5.2 ENSG00000204899 Mitotic spindle organizing protein 1 13 72708357-72727687 Predicted intracellular proteins Evidence at protein level HPA063299, HPA066715 Approved Renal cancer:1.01e-5 (unfavourable), Liver cancer:3.22e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.2 MZT2A FAM128A, MOZART2A ENSG00000173272 Mitotic spindle organizing protein 2A 2 131464900-131492743 Predicted intracellular proteins Evidence at protein level HPA051758, HPA052623 Approved Supported Centrosome
Cytosol Renal cancer:3.04e-11 (unfavourable), Breast cancer:3.04e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 40.6 MZT2B FAM128B, FLJ14346, MOZART2B ENSG00000152082 Mitotic spindle organizing protein 2B 2 130181737-130190729 Predicted intracellular proteins Evidence at protein level HPA051758, HPA052623 Approved Supported Centrosome
Cytosol Renal cancer:9.37e-8 (unfavourable), Liver cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all testis: 81.9 N4BP1 ENSG00000102921 NEDD4 binding protein 1 16 48538726-48620148 Predicted intracellular proteins Evidence at protein level HPA040849, HPA041080 Approved Approved Nucleoli fibrillar center Renal cancer:9.03e-8 (favourable) Expressed in all Expressed in all lung: 22.0 N4BP2L1 CG018 ENSG00000139597 NEDD4 binding protein 2-like 1 13 32400723-32428311 Predicted intracellular proteins Evidence at protein level HPA038971 Approved Uncertain Nucleoplasm
Cytosol Liver cancer:3.11e-4 (favourable) Expressed in all Expressed in all ovary: 47.6 N4BP2L2 CG005, PFAAP5 ENSG00000244754 NEDD4 binding protein 2-like 2 13 32432417-32538885 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039338, HPA039434, HPA059327 Approved Approved Nucleoplasm Expressed in all Expressed in all endometrium: 57.2 N6AMT2 ENSG00000150456 N-6 adenine-specific DNA methyltransferase 2 (putative) 13 20728731-20773958 Predicted intracellular proteins Evidence at protein level HPA040417, HPA042543 Uncertain Approved Plasma membrane
Cytosol Endometrial cancer:1.82e-4 (favourable) Expressed in all Expressed in all endometrium: 18.0 NAA10 ARD1, ARD1A, DXS707, TE2 ENSG00000102030 N(alpha)-acetyltransferase 10, NatA catalytic subunit X 153929242-153935223 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB006269, HPA030711 Supported Validated Nucleoli
Cytosol Renal cancer:3.29e-8 (unfavourable) Expressed in all Expressed in all smooth muscle: 25.3 NAA15 FLJ13340, NARG1, NATH, TBDN100 ENSG00000164134 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 4 139301455-139420033 Predicted intracellular proteins Evidence at protein level HPA023589, HPA050661 Approved Validated Cytosol Liver cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all testis: 24.1 NAA16 FLJ22054, MGC40612, NARG1L, PRO2435 ENSG00000172766 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 13 41311205-41377030 Predicted intracellular proteins Evidence at protein level HPA039761, HPA040157 Approved Validated Cytosol Expressed in all Expressed in all bone marrow: 14.5 NAA20 dJ1002M8.1, NAT3, NAT5 ENSG00000173418 N(alpha)-acetyltransferase 20, NatB catalytic subunit 20 20017116-20033655 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063344 Supported Cytosol Head and neck cancer:1.96e-4 (unfavourable) Expressed in all Expressed in all esophagus: 82.9 NAA25 C12orf30, FLJ13089 ENSG00000111300 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 12 112026689-112109022 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039322 Approved Supported Golgi apparatus
Cytosol Renal cancer:1.32e-8 (unfavourable), Liver cancer:5.53e-5 (unfavourable), Endometrial cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 9.4 NAA30 C14orf35, FLJ35355, MAK3, Mak3p, NAT12 ENSG00000139977 N(alpha)-acetyltransferase 30, NatC catalytic subunit 14 57390544-57415917 Enzymes, Predicted intracellular proteins Evidence at protein level HPA057824 Uncertain Supported Cytosol Renal cancer:1.25e-8 (favourable) Expressed in all Expressed in all testis: 34.2 NAA35 bA379P1.1, FLJ21613, FLJ22643, MAK10 ENSG00000135040 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 9 85941146-86022298 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021547, HPA051586 Approved Supported Vesicles Liver cancer:1.16e-7 (unfavourable) Expressed in all Expressed in all testis: 37.8 NAA38 LSMD1, MGC14151, PFAAP2 ENSG00000183011 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 17 7856685-7885238 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059189 Supported Nucleus Expressed in all Expressed in all testis: 78.6 NAA40 FLJ13848, NAT11 ENSG00000110583 N(alpha)-acetyltransferase 40, NatD catalytic subunit 11 63938959-63957328 Predicted intracellular proteins Evidence at protein level HPA037816 Uncertain Approved Nuclear bodies Liver cancer:1.43e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.2 NAA50 FLJ13194, MAK3, NAT13, NAT5, San ENSG00000121579 N(alpha)-acetyltransferase 50, NatE catalytic subunit 3 113716460-113746300 Predicted intracellular proteins Evidence at protein level Liver cancer:1.51e-5 (unfavourable), Pancreatic cancer:7.92e-5 (unfavourable), Endometrial cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 111.8 NAA60 FLJ14154, NAT15 ENSG00000122390 N(alpha)-acetyltransferase 60, NatF catalytic subunit 16 3443611-3486963 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040916 Approved Uncertain Actin filaments
Cytosol Endometrial cancer:3.14e-4 (favourable), Pancreatic cancer:4.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 84.6 NAAA ASAHL ENSG00000138744 N-acylethanolamine acid amidase 4 75913657-75941051 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026135 Approved Endometrial cancer:1.93e-4 (favourable), Pancreatic cancer:4.90e-4 (favourable) Expressed in all Expressed in all prostate: 112.5 NAB1 ENSG00000138386 NGFI-A binding protein 1 (EGR1 binding protein 1) 2 190646746-190692766 Predicted intracellular proteins Evidence at protein level HPA002738 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Pancreatic cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all skin: 80.7 NAB2 MADER ENSG00000166886 NGFI-A binding protein 2 (EGR1 binding protein 2) 12 57088894-57095476 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004510, HPA027464 Approved Approved Nucleus
Cytosol Renal cancer:9.38e-6 (unfavourable), Breast cancer:7.41e-4 (favourable) Expressed in all Expressed in all ovary: 39.3 NABP2 hSSB1, MGC2731, OBFC2B, SOSS-B1, SSB1 ENSG00000139579 Nucleic acid binding protein 2 12 56222015-56229854 Predicted intracellular proteins Evidence at protein level HPA044615, HPA057213 Supported Validated Nucleoplasm Liver cancer:7.44e-6 (unfavourable), Cervical cancer:8.35e-6 (favourable), Renal cancer:2.69e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 42.1 NACA NACA1 ENSG00000196531 Nascent polypeptide-associated complex alpha subunit 12 56712428-56731628 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA073152, HPA073648 Approved Cytosol Renal cancer:4.58e-11 (unfavourable) Expressed in all Expressed in all ovary: 2544.0 NACC1 BEND8, BTBD14B, BTBD30, NAC-1, NAC1 ENSG00000160877 Nucleus accumbens associated 1, BEN and BTB (POZ) domain containing 19 13118103-13141141 Predicted intracellular proteins Evidence at protein level HPA021238, HPA062245 Supported Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 37.2 NACC2 BEND9, BTBD14A, BTBD31, MGC23427 ENSG00000148411 NACC family member 2, BEN and BTB (POZ) domain containing 9 136006537-136095285 Predicted intracellular proteins Evidence at protein level HPA047924, HPA052962 Approved Approved Nucleoli
Mitochondria Renal cancer:8.28e-5 (favourable), Stomach cancer:8.63e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 46.9 NADK FLJ13052 ENSG00000008130 NAD kinase 1 1751232-1780457 Enzymes, Predicted intracellular proteins Evidence at protein level HPA048909, HPA053368 Uncertain Approved Nucleoplasm
Vesicles Expressed in all Expressed in all spleen: 78.8 NADK2 C5orf33, FLJ30596, MNADK, NADKD1 ENSG00000152620 NAD kinase 2, mitochondrial 5 36192592-36242279 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038366, HPA038367, HPA061492 Supported Expressed in all Expressed in all liver: 173.1 NADSYN1 FLJ10631 ENSG00000172890 NAD synthetase 1 11 71453109-71524107 Enzymes, Predicted intracellular proteins Evidence at protein level CAB017798, HPA038523, HPA038524 Approved Validated Cytosol Liver cancer:5.17e-6 (unfavourable), Renal cancer:8.72e-5 (unfavourable), Urothelial cancer:5.10e-4 (favourable) Expressed in all Expressed in all spleen: 42.1 NAE1 APPBP1, ula-1 ENSG00000159593 NEDD8 activating enzyme E1 subunit 1 16 66802875-66873256 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041178, HPA042041 Approved Approved Nucleus
Microtubules
Centrosome Liver cancer:3.92e-8 (unfavourable), Thyroid cancer:9.44e-5 (favourable) Expressed in all Expressed in all testis: 86.5 NAF1 ENSG00000145414 Nuclear assembly factor 1 ribonucleoprotein 4 163110073-163166921 Predicted intracellular proteins Evidence at protein level HPA036241, HPA036242, HPA066090 Approved Validated Nucleus
Cytosol Expressed in all Expressed in all testis: 33.2 NAGA D22S674 ENSG00000198951 N-acetylgalactosaminidase, alpha- 22 42058354-42070842 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA000649 Supported Expressed in all Expressed in all parathyroid gland: 62.5 NAGK GNK ENSG00000124357 N-acetylglucosamine kinase 2 71064344-71079805 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035206, HPA035207 Supported Approved Nucleus
Cytosol Renal cancer:4.35e-4 (unfavourable), Head and neck cancer:5.87e-4 (favourable), Endometrial cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all esophagus: 148.5 NAGLU NAG ENSG00000108784 N-acetylglucosaminidase, alpha 17 42536172-42544449 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038815 Supported Approved Renal cancer:2.58e-6 (favourable), Glioma:3.43e-4 (unfavourable), Endometrial cancer:4.17e-4 (favourable), Pancreatic cancer:6.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 47.4 NAMPT PBEF, PBEF1 ENSG00000105835 Nicotinamide phosphoribosyltransferase 7 106248285-106286326 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034349, HPA047776, HPA057722 Approved Approved Nuclear speckles
Cell Junctions Renal cancer:2.49e-6 (unfavourable), Pancreatic cancer:1.51e-4 (unfavourable), Cervical cancer:4.78e-4 (unfavourable), Head and neck cancer:8.81e-4 (unfavourable) Expressed in all Expressed in all appendix: 792.4 NANS SAS ENSG00000095380 N-acetylneuraminic acid synthase 9 98056739-98083075 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019223 Approved Approved Nucleoplasm Endometrial cancer:1.71e-4 (favourable), Liver cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all prostate: 149.7 NAP1L1 MGC23410, MGC8688, NAP1, NAP1L, NRP ENSG00000187109 Nucleosome assembly protein 1-like 1 12 76036587-76085033 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028861 Approved Uncertain Microtubules Renal cancer:6.14e-13 (unfavourable), Liver cancer:3.29e-9 (unfavourable) Expressed in all Expressed in all ovary: 740.7 NAP1L4 NAP2 ENSG00000205531 Nucleosome assembly protein 1-like 4 11 2944431-2992377 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011567 Approved Supported Nucleoplasm Liver cancer:1.68e-7 (unfavourable), Thyroid cancer:1.55e-4 (favourable), Cervical cancer:9.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 147.3 NAPA ENSG00000105402 N-ethylmaleimide-sensitive factor attachment protein, alpha 19 47487637-47515240 Predicted intracellular proteins Evidence at protein level CAB010100, HPA046149, HPA050196 Approved Uncertain Cytosol Renal cancer:4.26e-9 (favourable) Expressed in all Expressed in all prostate: 146.3 NAPG ENSG00000134265 N-ethylmaleimide-sensitive factor attachment protein, gamma 18 10525905-10552761 Predicted intracellular proteins Evidence at protein level HPA008208, HPA011389 Approved Approved Plasma membrane
Cytosol Renal cancer:8.14e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.6 NARF DKFZp434G0420, FLJ10067, IOP2 ENSG00000141562 Nuclear prelamin A recognition factor 17 82458180-82490537 Predicted intracellular proteins Evidence at protein level HPA053006 Supported Nucleus
Nucleoli Renal cancer:1.48e-10 (unfavourable), Cervical cancer:1.15e-4 (favourable) Expressed in all Expressed in all testis: 47.2 NARFL FLJ21988, HPRN, IOP1, PRN ENSG00000103245 Nuclear prelamin A recognition factor-like 16 729753-741329 Predicted intracellular proteins Evidence at protein level HPA040851 Approved Approved Plasma membrane
Cytosol Cervical cancer:1.32e-5 (favourable), Renal cancer:9.83e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 19.4 NARS NARS1 ENSG00000134440 Asparaginyl-tRNA synthetase 18 57600656-57622213 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034257, HPA040017 Supported Validated Cytosol Liver cancer:1.23e-7 (unfavourable), Renal cancer:1.73e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 151.7 NARS2 DFNB94, FLJ23441, SLM5 ENSG00000137513 Asparaginyl-tRNA synthetase 2, mitochondrial (putative) 11 78435961-78574874 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026793 Supported Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:1.22e-6 (favourable), Ovarian cancer:1.39e-5 (favourable) Expressed in all Expressed in all kidney: 19.7 NASP DKFZp547F162, FLB7527, FLJ31599, FLJ35510, MGC19722, MGC20372, MGC2297, PRO1999 ENSG00000132780 Nuclear autoantigenic sperm protein (histone-binding) 1 45583846-45618904 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028136, HPA030518, HPA030520 Supported Validated Nucleoplasm Renal cancer:1.91e-8 (unfavourable), Liver cancer:4.96e-6 (unfavourable), Melanoma:3.67e-4 (unfavourable) Expressed in all Expressed in all testis: 149.9 NAT10 FLJ10774, FLJ12179, hALP, KIAA1709, NET43 ENSG00000135372 N-acetyltransferase 10 (GCN5-related) 11 34105602-34147670 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB035546, HPA057576, HPA071628 Supported Validated Nucleoli
Midbody Liver cancer:9.61e-8 (unfavourable), Renal cancer:8.83e-5 (unfavourable), Head and neck cancer:1.07e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.0 NAT6 FUS2 ENSG00000243477 N-acetyltransferase 6 (GCN5-related) 3 50296402-50299421 Predicted intracellular proteins Evidence at protein level HPA039576 Approved Renal cancer:1.71e-4 (favourable), Breast cancer:3.62e-4 (favourable) Expressed in all Expressed in all testis: 45.8 NAT9 DKFZP564C103 ENSG00000109065 N-acetyltransferase 9 (GCN5-related, putative) 17 74770547-74776367 Predicted intracellular proteins Evidence at protein level HPA021820, HPA057149 Approved Approved Nucleoplasm Renal cancer:6.26e-6 (unfavourable), Pancreatic cancer:3.21e-5 (favourable), Liver cancer:3.25e-5 (unfavourable), Stomach cancer:7.80e-4 (favourable) Expressed in all Expressed in all adrenal gland: 39.3 NATD1 C17orf103, Gtlf3b, MGC33894 ENSG00000274180 N-acetyltransferase domain containing 1 17 21238870-21253410 Predicted intracellular proteins Evidence at protein level Renal cancer:3.55e-6 (favourable) Expressed in all Expressed in all thyroid gland: 16.9 NBAS NAG ENSG00000151779 Neuroblastoma amplified sequence 2 15166909-15561330 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036817 Approved Approved Nuclear membrane
Nucleoli
Golgi apparatus Urothelial cancer:5.84e-5 (unfavourable), Liver cancer:1.10e-4 (unfavourable) Expressed in all Expressed in all testis: 37.4 NBEAL2 KIAA0540 ENSG00000160796 Neurobeachin-like 2 3 46979683-47009703 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051969 Approved Head and neck cancer:4.60e-4 (favourable) Expressed in all Expressed in all bone marrow: 76.7 NBL1 D1S1733E, DAN, DAND1, NB, NO3 ENSG00000158747 Neuroblastoma 1, DAN family BMP antagonist 1 19640554-19658456 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA007394, CAB026132 Uncertain Expressed in all Expressed in all ovary: 551.6 NBN AT-V1, AT-V2, ATV, NBS, NBS1 ENSG00000104320 Nibrin 8 89933336-90003228 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001429, CAB003836 Supported Approved Nucleoplasm
Golgi apparatus Lung cancer:5.46e-5 (unfavourable), Pancreatic cancer:4.20e-4 (unfavourable) Expressed in all Expressed in all appendix: 38.1 NBPF10 AG1 ENSG00000271425 Neuroblastoma breakpoint family, member 10 1 146064699-146144942 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Not detected Expressed in all skin: 38.4 NBPF11 NBPF24 ENSG00000263956 Neuroblastoma breakpoint family, member 11 1 148102046-148152322 Predicted intracellular proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Urothelial cancer:3.20e-5 (favourable), Lung cancer:6.87e-4 (favourable) Mixed Expressed in all epididymis: 20.4 NBPF12 COAS1, KIAA1245 ENSG00000268043 Neuroblastoma breakpoint family, member 12 1 146938744-146996202 Predicted intracellular proteins Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Pancreatic cancer:9.01e-7 (favourable), Urothelial cancer:2.47e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 19.6 NBPF14 DJ328E19.C1.1 ENSG00000270629 Neuroblastoma breakpoint family, member 14 1 148531385-148679751 Predicted intracellular proteins Evidence at protein level HPA038748, HPA038752, HPA042595, HPA043105, HPA043692, HPA044023, HPA046392, HPA046971, HPA058050 Uncertain Approved Vesicles Mixed Expressed in all skin: 53.0 NBPF15 MGC8902, NBPF16 ENSG00000266338 Neuroblastoma breakpoint family, member 15 1 144421386-144461674 Predicted intracellular proteins Evidence at protein level HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Renal cancer:4.11e-5 (unfavourable) Expressed in all Expressed in all epididymis: 24.7 NBPF19 ENSG00000271383 Neuroblastoma breakpoint family, member 19 1 149390623-149556361 Predicted intracellular proteins Evidence at protein level HPA042595, HPA043105, HPA043692, HPA044023, HPA046392, HPA046971, HPA058050 Uncertain Approved Vesicles Mixed Expressed in all skin: 74.9 NBPF9 AE01 ENSG00000269713 Neuroblastoma breakpoint family, member 9 1 149054027-149103561 Predicted intracellular proteins Evidence at protein level HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050 Approved Approved Vesicles Mixed Expressed in all thyroid gland: 22.4 NBR1 1A1-3B, CA125, KIAA0049, M17S2 ENSG00000188554 Neighbor of BRCA1 gene 1 17 43170481-43211689 Predicted intracellular proteins Evidence at protein level HPA022944, HPA022999, HPA023999 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Renal cancer:2.00e-5 (favourable) Expressed in all Expressed in all testis: 259.1 NCALD ENSG00000104490 Neurocalcin delta 8 101686543-102124907 Predicted intracellular proteins Evidence at protein level HPA043245 Approved Pancreatic cancer:5.30e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 125.4 NCAPD2 CAP-D2, CNAP1, hCAP-D2, KIAA0159 ENSG00000010292 Non-SMC condensin I complex, subunit D2 12 6493356-6531955 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012423, HPA036947, HPA037363 Supported Supported Nucleus
Cytosol Liver cancer:1.79e-8 (unfavourable), Renal cancer:1.13e-7 (unfavourable) Expressed in all Expressed in all lymph node: 29.1 NCAPH2 384D8-2, CAP-H2, hCAP-H2 ENSG00000025770 Non-SMC condensin II complex, subunit H2 22 50508216-50523472 Predicted intracellular proteins Evidence at protein level HPA067932, HPA069056 Supported Validated Nucleoplasm
Cytokinetic bridge Cervical cancer:2.24e-8 (favourable), Liver cancer:8.25e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 49.6 NCBP1 CBP80, NCBP, Sto1 ENSG00000136937 Nuclear cap binding protein subunit 1, 80kDa 9 97633626-97673748 Predicted intracellular proteins, Transporters Evidence at protein level HPA042411, HPA049031 Supported Supported Nucleoplasm
Cytosol Prostate cancer:4.17e-4 (unfavourable), Colorectal cancer:5.28e-4 (favourable) Expressed in all Expressed in all testis: 32.3 NCBP2 Cbc2, CBP20, NIP1 ENSG00000114503 Nuclear cap binding protein subunit 2, 20kDa 3 196935402-196942597 Predicted intracellular proteins, Transporters Evidence at protein level HPA044850, HPA062483 Supported Validated Nucleoplasm Liver cancer:2.37e-7 (unfavourable), Prostate cancer:2.27e-4 (unfavourable), Pancreatic cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 79.5 NCBP2-AS2 ENSG00000270170 NCBP2 antisense RNA 2 (head to head) 3 196942623-196943540 Predicted secreted proteins Evidence at protein level Renal cancer:8.92e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 28.7 NCBP3 C17orf85, ELG, HSA277841 ENSG00000074356 Nuclear cap binding subunit 3 17 3802165-3846251 Predicted intracellular proteins Evidence at protein level HPA008959, HPA013195 Supported Approved Nuclear speckles Melanoma:4.68e-4 (unfavourable), Prostate cancer:4.90e-4 (unfavourable) Expressed in all Expressed in all testis: 16.4 NCK1 NCK, NCKalpha ENSG00000158092 NCK adaptor protein 1 3 136862208-136949823 Predicted intracellular proteins Evidence at protein level CAB005063, HPA030766 Supported Validated Plasma membrane
Cytosol Pancreatic cancer:9.14e-5 (unfavourable), Renal cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all lymph node: 49.5 NCK2 NCKbeta ENSG00000071051 NCK adaptor protein 2 2 105744897-105894274 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016116, HPA031004 Approved Expressed in all Expressed in all small intestine: 59.5 NCKAP5L KIAA1602 ENSG00000167566 NCK-associated protein 5-like 12 49791146-49828750 Predicted intracellular proteins Evidence at protein level HPA041034 Approved Approved Golgi apparatus Renal cancer:1.16e-5 (unfavourable), Liver cancer:2.07e-4 (unfavourable), Pancreatic cancer:4.87e-4 (favourable) Expressed in all Expressed in all placenta: 12.8 NCL C23 ENSG00000115053 Nucleolin 2 231453531-231483641 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004210, HPA023981 Supported Validated Nucleus
Nucleoli Liver cancer:1.41e-6 (unfavourable), Endometrial cancer:2.28e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 440.8 NCLN NET59, NICALIN ENSG00000125912 Nicalin 19 3185563-3209575 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006625 Approved Uncertain Nucleoplasm
Lipid droplets Renal cancer:8.37e-5 (unfavourable), Stomach cancer:8.82e-5 (favourable), Endometrial cancer:1.19e-4 (favourable), Liver cancer:2.15e-4 (unfavourable) Expressed in all Expressed in all duodenum: 34.8 NCOA1 bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1 ENSG00000084676 Nuclear receptor coactivator 1 2 24491914-24770702 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB019402, HPA070213, HPA070520 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 58.0 NCOA2 bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2 ENSG00000140396 Nuclear receptor coactivator 2 8 70109762-70403805 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060243 Supported Nucleoplasm
Nuclear bodies Renal cancer:5.08e-4 (favourable) Expressed in all Expressed in all epididymis: 35.4 NCOA3 ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1 ENSG00000124151 Nuclear receptor coactivator 3 20 47501902-47656877 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009800, HPA024210 Supported Supported Nucleoplasm
Cytosol Liver cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all lymph node: 45.3 NCOA4 ARA70, DKFZp762E1112, ELE1, PTC3, RFG ENSG00000266412 Nuclear receptor coactivator 4 10 46005088-46030714 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA051260, HPA065208 Uncertain Approved Nucleoli
Golgi apparatus
Cytosol Renal cancer:8.04e-6 (favourable), Glioma:2.88e-4 (favourable) Expressed in all Expressed in all duodenum: 253.9 NCOA5 bA465L10.6, CIA ENSG00000124160 Nuclear receptor coactivator 5 20 46060985-46089952 Predicted intracellular proteins Evidence at protein level HPA050231 Uncertain Supported Nucleus
Actin filaments Liver cancer:1.41e-5 (unfavourable), Pancreatic cancer:1.09e-4 (favourable), Lung cancer:8.07e-4 (favourable) Expressed in all Expressed in all testis: 47.8 NCOA6 AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP ENSG00000198646 Nuclear receptor coactivator 6 20 34689097-34825649 Predicted intracellular proteins Evidence at protein level HPA004198, HPA050211 Supported Supported Nucleoplasm Renal cancer:8.78e-5 (favourable), Liver cancer:4.65e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.8 NCOA7 dJ187J11.3, ERAP140, TLDC4 ENSG00000111912 Nuclear receptor coactivator 7 6 125781161-125932030 Predicted intracellular proteins Evidence at protein level HPA030289, HPA030290, HPA030291, HPA030292 Approved Approved Nuclear bodies
Golgi apparatus Renal cancer:1.78e-6 (favourable) Expressed in all Expressed in all urinary bladder: 91.4 NCOR1 hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1 ENSG00000141027 Nuclear receptor corepressor 1 17 16029157-16218185 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043246, HPA050288, HPA051168, CAB072830 Supported Validated Nucleoplasm
Cytosol Renal cancer:7.92e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 84.0 NCOR2 CTG26, SMRT, SMRTE, TNRC14, TRAC-1 ENSG00000196498 Nuclear receptor corepressor 2 12 124324415-124567589 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001928 Approved Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 81.4 NCSTN APH2, KIAA0253 ENSG00000162736 Nicastrin 1 160343272-160358952 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB021982, HPA054846, HPA070642 Approved Approved Cytosol Renal cancer:7.75e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 140.4 NDEL1 MITAP1, NDE1L1, NDE2, NUDEL ENSG00000166579 NudE neurodevelopment protein 1-like 1 17 8413131-8490411 Predicted intracellular proteins Evidence at protein level HPA017916 Approved Expressed in all Expressed in all adrenal gland: 81.9 NDFIP1 MGC10924, N4WBP5 ENSG00000131507 Nedd4 family interacting protein 1 5 142108505-142154443 Predicted membrane proteins Evidence at protein level HPA009682 Approved Head and neck cancer:2.33e-7 (unfavourable), Renal cancer:2.39e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 246.7 NDFIP2 KIAA1165, N4wbp5a ENSG00000102471 Nedd4 family interacting protein 2 13 79481124-79556075 Predicted membrane proteins Evidence at protein level HPA009160 Uncertain Validated Vesicles Renal cancer:4.18e-5 (favourable), Head and neck cancer:5.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 96.3 NDNL2 HCA4, MAGEG1, MAGEL3, NSE3, NSMCE3 ENSG00000185115 Necdin-like 2, SMC5-SMC6 complex component 15 29268149-29269829 Predicted intracellular proteins Evidence at protein level Head and neck cancer:1.94e-4 (unfavourable) Expressed in all Expressed in all testis: 18.8 NDRG1 CAP43, DRG1, NDR1, RTP, TDD5 ENSG00000104419 N-myc downstream regulated 1 8 133237171-133302022 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006881 Approved Supported Microtubules
Cytosol Liver cancer:1.47e-4 (unfavourable), Renal cancer:4.13e-4 (unfavourable), Glioma:7.24e-4 (unfavourable) Expressed in all Expressed in all prostate: 487.4 NDRG2 KIAA1248, SYLD ENSG00000165795 NDRG family member 2 14 21016763-21070872 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002896, HPA003590, CAB017491 Supported Approved Nucleoplasm
Microtubule organizing center
Cytosol Renal cancer:1.43e-12 (favourable), Liver cancer:6.71e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1032.4 NDRG3 ENSG00000101079 NDRG family member 3 20 36651766-36746078 Predicted intracellular proteins Evidence at protein level HPA017851, HPA018256 Approved Liver cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 124.8 NDST1 HSST, NST1 ENSG00000070614 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 5 150485818-150558211 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA060532 Approved Ovarian cancer:5.13e-4 (unfavourable), Endometrial cancer:6.99e-4 (unfavourable) Expressed in all Expressed in all spleen: 60.7 NDST2 HSST2, NST2 ENSG00000166507 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 10 73801911-73811798 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051515 Approved Approved Cytosol Mixed Expressed in all spleen: 44.9 NDUFA1 CI-MWFE, MWFE ENSG00000125356 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa X 119871487-119876662 Disease related genes, Predicted membrane proteins Evidence at protein level HPA029768, HPA054359 Supported Supported Mitochondria
Cytosol Renal cancer:3.48e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 224.9 NDUFA10 CI-42k ENSG00000130414 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2 239892450-240025402 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA059529 Supported Mitochondria Renal cancer:2.09e-7 (favourable), Melanoma:2.95e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 65.8 NDUFA11 B14.7 ENSG00000174886 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 19 5891276-5904006 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA072209 Uncertain Mitochondria Endometrial cancer:3.38e-5 (favourable), Cervical cancer:4.54e-5 (favourable) Expressed in all Expressed in all heart muscle: 298.5 NDUFA12 B17.2, DAP13 ENSG00000184752 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 12 94897055-95003770 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039903 Supported Supported Mitochondria Expressed in all Expressed in all heart muscle: 190.0 NDUFA13 B16.6, CDA016, CGI-39, GRIM-19, GRIM19 ENSG00000186010 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 19 19515736-19529054 Disease related genes, Predicted membrane proteins Evidence at protein level HPA041213 Supported Validated Mitochondria Expressed in all Expressed in all heart muscle: 220.4 NDUFA2 B8 ENSG00000131495 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 5 140638740-140647785 Predicted intracellular proteins Evidence at protein level HPA035933 Uncertain Cervical cancer:6.53e-4 (favourable) Expressed in all Expressed in all adrenal gland: 117.9 NDUFA3 B9 ENSG00000170906 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 19 54102728-54109257 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046976 Supported Urothelial cancer:4.80e-4 (favourable), Pancreatic cancer:9.65e-4 (favourable) Expressed in all Expressed in all skin: 16.0 NDUFA4 CI-9k, MLRQ ENSG00000189043 NDUFA4, mitochondrial complex associated 7 10931951-10940256 Disease related genes, Predicted membrane proteins Evidence at protein level HPA055323 Supported Mitochondria Renal cancer:4.61e-8 (favourable) Expressed in all Expressed in all heart muscle: 249.3 NDUFA5 B13, CI-13kB, CI-13KD-B, NUFM, UQOR13 ENSG00000128609 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 7 123536997-123558255 Predicted intracellular proteins Evidence at protein level HPA043175 Supported Renal cancer:3.99e-9 (favourable), Breast cancer:8.47e-5 (favourable) Expressed in all Expressed in all thyroid gland: 249.5 NDUFA6 B14, CI-B14, LYRM6, NADHB14 ENSG00000184983 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 22 42085525-42090955 Predicted intracellular proteins Evidence at protein level Renal cancer:1.05e-6 (favourable), Cervical cancer:3.87e-4 (favourable), Endometrial cancer:4.96e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.5 NDUFA7 B14.5a ENSG00000267855 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 19 8308768-8321396 Predicted intracellular proteins Evidence at protein level HPA059251, HPA071866 Supported Supported Mitochondria Expressed in all Expressed in all heart muscle: 67.3 NDUFA8 MGC793, PGIV ENSG00000119421 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 9 122144058-122159819 Predicted intracellular proteins Evidence at protein level HPA041510, HPA041600 Supported Validated Mitochondria Renal cancer:4.17e-6 (favourable) Expressed in all Expressed in all heart muscle: 226.6 NDUFA9 CI-39k, NDUFS2L, SDR22E1 ENSG00000139180 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 12 4649095-4694317 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042268, HPA073212 Supported Supported Nucleoplasm
Mitochondria Renal cancer:2.57e-7 (favourable), Urothelial cancer:5.75e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 38.4 NDUFAB1 ACP, FASN2A, SDAP ENSG00000004779 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 16 23581002-23596356 Predicted intracellular proteins Evidence at protein level HPA054364 Uncertain Supported Nucleoplasm
Mitochondria Renal cancer:1.94e-7 (favourable) Expressed in all Expressed in all heart muscle: 183.8 NDUFAF1 CGI-65, CIA30 ENSG00000137806 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 15 41387349-41402519 Predicted intracellular proteins Evidence at protein level HPA039933, HPA040064 Supported Validated Cytosol Renal cancer:3.34e-6 (favourable), Liver cancer:2.88e-5 (favourable) Expressed in all Expressed in all testis: 45.2 NDUFAF2 B17.2L, mimitin, MMTN, NDUFA12L ENSG00000164182 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 5 60945129-61153037 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048082, HPA054776 Supported Validated Mitochondria Renal cancer:2.49e-4 (unfavourable), Liver cancer:2.56e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 48.2 NDUFAF3 2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527 ENSG00000178057 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 3 49020459-49023495 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035376, HPA035377 Supported Renal cancer:1.86e-5 (favourable) Expressed in all Expressed in all testis: 287.4 NDUFAF4 bA22L21.1, C6orf66, HRPAP20, HSPC125, My013 ENSG00000123545 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 6 96889313-96897881 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046560 Uncertain Supported Mitochondria Breast cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 29.1 NDUFB1 CI-MNLL, MNLL ENSG00000183648 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 14 92116122-92121917 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA063737 Supported Nuclear speckles
Mitochondria Renal cancer:1.31e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 278.9 NDUFB10 PDSW ENSG00000140990 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 16 1959508-1961975 Predicted intracellular proteins Evidence at protein level HPA073189 Supported Renal cancer:9.43e-6 (favourable), Cervical cancer:7.38e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 449.7 NDUFB11 ESSS, Np15, NP17.3 ENSG00000147123 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa X 47142216-47145504 Disease related genes, Predicted membrane proteins Evidence at protein level HPA030367 Supported Validated Mitochondria Expressed in all Expressed in all skeletal muscle: 129.1 NDUFB2 AGGG, CI-AGGG ENSG00000090266 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 7 140690777-140722790 Predicted intracellular proteins Evidence at protein level HPA051377 Approved Renal cancer:7.60e-7 (favourable) Expressed in all Expressed in all thyroid gland: 495.8 NDUFB3 B12 ENSG00000119013 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 2 201071433-201085750 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034596 Approved Head and neck cancer:7.24e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 180.0 NDUFB4 B15 ENSG00000065518 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 3 120596309-120602500 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051739 Supported Supported Nuclear membrane
Mitochondria Urothelial cancer:1.79e-4 (favourable) Expressed in all Expressed in all adrenal gland: 365.9 NDUFB5 CI-SGDH, MGC12314, SGDH ENSG00000136521 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 3 179604690-179627647 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA005640 Supported Supported Nucleoplasm
Mitochondria Renal cancer:3.32e-5 (favourable) Expressed in all Expressed in all heart muscle: 133.4 NDUFB6 B17, CI ENSG00000165264 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 9 32552999-32573184 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044001, HPA053334 Supported Validated Mitochondria Renal cancer:7.47e-10 (favourable), Cervical cancer:3.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 70.5 NDUFB7 B18, CI-B18, MGC2480 ENSG00000099795 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 19 14566078-14572062 Predicted intracellular proteins Evidence at protein level HPA002817 Approved Renal cancer:2.41e-4 (favourable), Cervical cancer:3.54e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 248.7 NDUFB8 ASHI, CI-ASHI ENSG00000166136 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 10 100523740-100530000 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA003886 Supported Supported Mitochondria Expressed in all Expressed in all heart muscle: 292.4 NDUFB9 B22, LYRM3, UQOR22 ENSG00000147684 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 8 124539103-124568510 Predicted intracellular proteins Evidence at protein level HPA042768 Approved Supported Mitochondria Renal cancer:3.42e-5 (favourable) Expressed in all Expressed in all skeletal muscle: 443.2 NDUFC1 KFYI ENSG00000109390 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4 139266880-139302551 Predicted membrane proteins Evidence at protein level HPA044556 Approved Supported Mitochondria Endometrial cancer:8.23e-5 (favourable), Urothelial cancer:7.25e-4 (favourable), Renal cancer:9.96e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 86.7 NDUFC2 B14.5b, HLC-1 ENSG00000151366 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 11 78068304-78080219 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038873, HPA056195 Approved Supported Mitochondria Renal cancer:5.00e-5 (favourable) Expressed in all Expressed in all thyroid gland: 369.3 NDUFS1 CI-75k ENSG00000023228 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2 206114817-206159603 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA064605, CAB070844 Approved Supported Mitochondria Renal cancer:1.47e-12 (favourable), Breast cancer:3.85e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 141.0 NDUFS2 CI-49 ENSG00000158864 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1 161197104-161214395 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA055140, HPA061953 Supported Validated Nucleoplasm
Mitochondria Renal cancer:2.32e-4 (favourable) Expressed in all Expressed in all heart muscle: 126.4 NDUFS3 CI-30 ENSG00000213619 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 11 47565336-47584562 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004484 Approved Supported Nuclear bodies
Mitochondria Renal cancer:2.61e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 127.3 NDUFS4 AQDQ, CI-18 ENSG00000164258 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 5 53560633-53683340 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003884 Supported Supported Mitochondria Renal cancer:3.85e-6 (favourable) Expressed in all Expressed in all kidney: 138.5 NDUFS5 CI-15k ENSG00000168653 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 1 39026318-39034636 Predicted intracellular proteins Evidence at protein level HPA042582 Supported Approved Nucleus
Cytosol Ovarian cancer:3.54e-4 (favourable) Expressed in all Expressed in all epididymis: 631.1 NDUFS6 CI-13kA ENSG00000145494 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 5 1801400-1816605 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064221 Supported Expressed in all Expressed in all skeletal muscle: 112.0 NDUFS8 CI-23k, TYKY ENSG00000110717 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 11 68030617-68036644 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018524 Approved Supported Mitochondria Renal cancer:3.27e-8 (favourable) Expressed in all Expressed in all adrenal gland: 153.3 NDUFV1 CI-51K ENSG00000167792 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 11 67606852-67612535 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA045211, HPA075051 Approved Supported Mitochondria
Cytosol Renal cancer:7.49e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 218.0 NDUFV2 CI-24k ENSG00000178127 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 18 9102630-9134345 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003404, HPA077896 Supported Approved Supported Mitochondria Expressed in all Expressed in all skeletal muscle: 190.9 NDUFV3 CI-10k ENSG00000160194 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 21 42879644-42913304 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019791, HPA020463, HPA030427, CAB034142 Supported Validated Mitochondria Expressed in all Expressed in all skeletal muscle: 29.0 NECAP1 DKFZP566B183 ENSG00000089818 NECAP endocytosis associated 1 12 8082211-8097771 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053980, HPA063300 Uncertain Approved Vesicles
Cytosol Expressed in all Expressed in all cerebral cortex: 115.2 NECAP2 FLJ10420 ENSG00000157191 NECAP endocytosis associated 2 1 16440672-16460078 Predicted intracellular proteins Evidence at protein level HPA028077 Approved Approved Endoplasmic reticulum Liver cancer:6.13e-4 (unfavourable) Expressed in all Expressed in all spleen: 87.6 NEDD1 GCP-WD, TUBGCP7 ENSG00000139350 Neural precursor cell expressed, developmentally down-regulated 1 12 96907223-96953777 Predicted intracellular proteins Evidence at protein level HPA038591 Approved Liver cancer:1.94e-4 (unfavourable), Lung cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all testis: 42.6 NEDD4L KIAA0439, NEDD4-2, RSP5 ENSG00000049759 Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 18 58044367-58401540 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA024618, HPA064730 Approved Approved Focal adhesion sites Renal cancer:6.55e-15 (favourable) Expressed in all Expressed in all prostate: 69.9 NEDD8 Nedd-8 ENSG00000129559 Neural precursor cell expressed, developmentally down-regulated 8 14 24216852-24232454 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004082 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 548.6 NEDD9 CAS-L, CASS2, HEF1 ENSG00000111859 Neural precursor cell expressed, developmentally down-regulated 9 6 11183298-11382348 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009720, HPA038768, HPA039270 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all lung: 109.7 NEIL1 FLJ22402, FPG1, hFPG1, NEI1 ENSG00000140398 Nei-like DNA glycosylase 1 15 75346955-75357114 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054084 Approved Supported Nucleoplasm Pancreatic cancer:2.09e-4 (favourable) Expressed in all Expressed in all adrenal gland: 10.6 NEIL2 FLJ31644, MGC2832, MGC4505, NEH2 ENSG00000154328 Nei-like DNA glycosylase 2 8 11769639-11787346 Enzymes, Predicted intracellular proteins Evidence at protein level HPA064460 Supported Nucleus
Nucleoli Expressed in all Expressed in all testis: 46.1 NEK3 HSPK36, MGC29949 ENSG00000136098 NIMA-related kinase 3 13 52132639-52159861 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019062, HPA043230 Supported Approved Microtubules Expressed in all Expressed in all testis: 29.5 NEK4 NRK2, pp12301, STK2 ENSG00000114904 NIMA-related kinase 4 3 52708449-52770949 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015750 Approved Approved Nucleoplasm Colorectal cancer:2.69e-5 (favourable) Expressed in all Expressed in all testis: 83.9 NEK6 SID6-1512 ENSG00000119408 NIMA-related kinase 6 9 124257606-124353307 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level CAB045993, HPA056828 Approved Supported Nucleoplasm
Microtubule organizing center
Cytosol Testis cancer:7.66e-4 (unfavourable) Expressed in all Expressed in all appendix: 45.6 NEK7 ENSG00000151414 NIMA-related kinase 7 1 198156963-198322420 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA015520, HPA018193 Approved Supported Nucleoplasm Expressed in all Expressed in all heart muscle: 88.6 NEK9 DKFZp434D0935, MGC16714, Nek8, NERCC ENSG00000119638 NIMA-related kinase 9 14 75079353-75127344 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA001405 Approved Approved Mitochondria Pancreatic cancer:5.63e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.1 NELFA NELF-A, WHSC2 ENSG00000185049 Negative elongation factor complex member A 4 1982714-2041903 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009960, HPA039858, HPA043931 Supported Validated Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:4.35e-4 (unfavourable) Expressed in all Expressed in all testis: 31.9 NELFB COBRA1, KIAA1182, NELF-B ENSG00000188986 Negative elongation factor complex member B 9 137255173-137273547 Predicted intracellular proteins Evidence at protein level HPA020259 Supported Validated Nucleoplasm Renal cancer:4.31e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 40.6 NELFCD HSPC130, NELF-C, NELF-D, TH1, TH1L ENSG00000101158 Negative elongation factor complex member C/D 20 58981208-58995133 Predicted intracellular proteins Evidence at protein level HPA050641, HPA066262 Supported Nucleoplasm
Nuclear bodies
Vesicles
Cytosol Endometrial cancer:4.98e-5 (unfavourable), Liver cancer:1.90e-4 (unfavourable), Prostate cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 51.3 NELFE D6S45, NELF-E, RD, RDBP, RDP ENSG00000204356 Negative elongation factor complex member E 6 31952087-31959110 Predicted intracellular proteins Evidence at protein level HPA007187, HPA007594, HPA046502 Approved Validated Nucleoplasm
Nuclear bodies Renal cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all testis: 49.6 NEMF FLJ10051, NY-CO-1, SDCCAG1 ENSG00000165525 Nuclear export mediator factor 14 49782083-49853203 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004160 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:2.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 45.1 NENF CIR2, SCIRP10, SPUF ENSG00000117691 Neudesin neurotrophic factor 1 212432887-212446379 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA026763, HPA028488 Uncertain Validated Nucleus Renal cancer:1.54e-6 (unfavourable) Expressed in all Expressed in all cervix, uterine: 82.4 NET1 ARHGEF8, NET1A ENSG00000173848 Neuroepithelial cell transforming 1 10 5412551-5458463 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020068 Uncertain Approved Nucleus
Vesicles Liver cancer:3.87e-5 (unfavourable), Pancreatic cancer:8.27e-4 (unfavourable) Expressed in all Expressed in all rectum: 98.1 NEURL4 KIAA1787 ENSG00000215041 Neuralized E3 ubiquitin protein ligase 4 17 7315628-7329393 Predicted intracellular proteins Evidence at protein level HPA043678, HPA055314 Uncertain Pancreatic cancer:2.34e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 19.0 NF1 ENSG00000196712 Neurofibromin 1 17 31094927-31382116 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA045502 Uncertain Approved Mitochondria Expressed in all Expressed in all parathyroid gland: 31.9 NF2 merlin ENSG00000186575 Neurofibromin 2 (merlin) 22 29603556-29698598 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003097, CAB005385 Supported Validated Nucleus
Plasma membrane
Cytosol Renal cancer:2.89e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 57.6 NFAT5 KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP ENSG00000102908 Nuclear factor of activated T-cells 5, tonicity-responsive 16 69565094-69704666 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057304, HPA069711 Approved Supported Nucleus
Cytosol Renal cancer:1.08e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 37.6 NFATC2 NF-ATP, NFAT1, NFATp ENSG00000101096 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 20 51386957-51562831 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008789, CAB018567, HPA024369 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.57e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 26.8 NFATC2IP ESC2, FLJ14639, NIP45, RAD60 ENSG00000176953 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 16 28950807-28967097 Predicted intracellular proteins Evidence at protein level HPA053587 Approved Nucleus Renal cancer:1.03e-5 (unfavourable), Prostate cancer:5.23e-4 (unfavourable) Expressed in all Expressed in all lymph node: 43.2 NFATC3 NFAT4, NFATX ENSG00000072736 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 16 68084751-68229259 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004514, HPA023844, HPA050665 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 49.9 NFE2L1 FLJ00380, LCR-F1, NRF1, TCF11 ENSG00000082641 Nuclear factor, erythroid 2-like 1 17 48048329-48061487 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA063384, HPA065424 Approved Approved Nucleus
Cytosol Renal cancer:5.79e-6 (favourable), Endometrial cancer:8.20e-5 (favourable), Head and neck cancer:2.73e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 468.1 NFE2L2 NRF2 ENSG00000116044 Nuclear factor, erythroid 2-like 2 2 177227595-177392697 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002990, CAB020317, HPA043438 Supported Approved Nucleus
Plasma membrane
Cytosol Renal cancer:2.26e-4 (favourable) Expressed in all Expressed in all esophagus: 267.9 NFIA KIAA1439, NFI-L ENSG00000162599 Nuclear factor I/A 1 60865259-61462793 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006111, HPA008884 Supported Validated Nucleoplasm Urothelial cancer:2.03e-4 (unfavourable), Renal cancer:7.01e-4 (favourable), Head and neck cancer:7.30e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.5 NFIC CTF, CTF5, NF-I, NFI ENSG00000141905 Nuclear factor I/C (CCAAT-binding transcription factor) 19 3359563-3469217 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004300, CAB004674, HPA052625 Supported Validated Nucleus
Nucleoli fibrillar center Endometrial cancer:1.52e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 68.9 NFIL3 E4BP4, IL3BP1, NF-IL3A, NFIL3A ENSG00000165030 Nuclear factor, interleukin 3 regulated 9 91409045-91423862 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003261 Approved Approved Nuclear bodies Renal cancer:3.23e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 137.4 NFIX NF1A ENSG00000008441 Nuclear factor I/X (CCAAT-binding transcription factor) 19 12995608-13098796 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007533 Supported Supported Nucleoplasm Lung cancer:2.35e-4 (favourable), Liver cancer:4.66e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 192.0 NFKB1 KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50 ENSG00000109320 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4 102501329-102617302 Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB004031, HPA027305 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.76e-4 (favourable) Expressed in all Expressed in all bone marrow: 57.0 NFKB2 LYT-10, NF-kB2, p105, p52 ENSG00000077150 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 10 102394110-102402529 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA008422, CAB022098, HPA023900 Supported Approved Nucleoplasm
Cytosol Renal cancer:6.69e-12 (unfavourable), Melanoma:8.45e-5 (favourable), Colorectal cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all appendix: 72.8 NFKBIA IkappaBalpha, IKBA, MAD-3, NFKBI ENSG00000100906 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 14 35401511-35404749 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003815, HPA029207 Approved Validated Cytosol Breast cancer:1.33e-5 (favourable) Expressed in all Expressed in all bone marrow: 713.0 NFKBIZ FLJ34463, INAP, MAIL ENSG00000144802 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 3 101827991-101861022 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA010547, HPA075363 Supported Supported Nuclear speckles
Cytoplasmic bodies Renal cancer:4.30e-8 (unfavourable) Expressed in all Expressed in all bone marrow: 269.0 NFRKB DKFZp547B2013, INO80G ENSG00000170322 Nuclear factor related to kappaB binding protein 11 129863636-129895590 Predicted intracellular proteins Evidence at protein level HPA007082, HPA007128 Approved Validated Nucleus Liver cancer:5.78e-4 (unfavourable) Expressed in all Expressed in all testis: 38.0 NFS1 IscS, NifS ENSG00000244005 NFS1 cysteine desulfurase 20 35668055-35699359 Enzymes, Predicted intracellular proteins Evidence at protein level CAB034314, HPA051801, HPA054755 Supported Supported Nucleoplasm
Cytosol Renal cancer:4.72e-6 (favourable) Expressed in all Expressed in all kidney: 43.4 NFU1 CGI-33, HIRIP5, NifU, NIFUC ENSG00000169599 NFU1 iron-sulfur cluster scaffold 2 69395750-69437628 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035826 Uncertain Supported Nucleoplasm
Cytosol Expressed in all Expressed in all adipose tissue: 71.1 NFX1 MGC20369, NFX2, TEG-42, Tex42 ENSG00000086102 Nuclear transcription factor, X-box binding 1 9 33290511-33371157 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056310, HPA061382, HPA073519 Approved Validated Nucleus
Cytosol Ovarian cancer:3.75e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.6 NFYA CBF-B, HAP2, NF-YA ENSG00000001167 Nuclear transcription factor Y, alpha 6 41072945-41099976 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009250, HPA050779 Supported Supported Nucleoplasm Liver cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all testis: 71.0 NFYB CBF-A, HAP3, NF-YB ENSG00000120837 Nuclear transcription factor Y, beta 12 104117077-104138289 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004211 Supported Supported Nucleoplasm Renal cancer:9.28e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 122.9 NFYC CBF-C, NF-YC ENSG00000066136 Nuclear transcription factor Y, gamma 1 40691570-40771603 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055011 Supported Nucleoplasm Renal cancer:1.24e-4 (favourable), Liver cancer:7.24e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 60.0 NGDN C14orf120, DKFZP564O092, LCP5, lpd-2, NGD ENSG00000129460 Neuroguidin, EIF4E binding protein 14 23469688-23509862 Predicted intracellular proteins Evidence at protein level HPA000944 Approved Approved Nucleus
Nucleoli
Mitochondria Expressed in all Expressed in all endometrium: 54.8 NGFRAP1 Bex, BEX3, DXS6984E, HGR74, NADE ENSG00000166681 Nerve growth factor receptor (TNFRSF16) associated protein 1 X 103376340-103378077 Predicted intracellular proteins Evidence at protein level HPA018886 Approved Supported Cytosol Endometrial cancer:7.23e-5 (unfavourable), Renal cancer:1.28e-4 (favourable), Stomach cancer:3.48e-4 (unfavourable) Expressed in all Expressed in all epididymis: 599.3 NGLY1 FLJ11005, PNG1 ENSG00000151092 N-glycanase 1 3 25718944-25790039 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036825 Approved Liver cancer:1.96e-6 (unfavourable), Colorectal cancer:1.17e-5 (favourable) Expressed in all Expressed in all testis: 115.4 NHEJ1 Cernunnos, FLJ12610, XLF ENSG00000187736 Nonhomologous end-joining factor 1 2 219075317-219160865 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB012334, HPA043869 Approved Supported Nucleus
Nucleoli fibrillar center Mixed Expressed in all testis: 43.8 NHLRC2 DKFZp779F115, FLJ20147, FLJ25621, FLJ33312, MGC45492 ENSG00000196865 NHL repeat containing 2 10 113854661-113917194 Predicted intracellular proteins Evidence at protein level HPA038493, HPA057564 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 18.3 NHLRC3 ENSG00000188811 NHL repeat containing 3 13 39038306-39050109 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013738 Uncertain Expressed in all Expressed in all thyroid gland: 27.8 NHP2 FLJ20479, NOLA2 ENSG00000145912 NHP2 ribonucleoprotein 5 178149460-178153967 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA044171, HPA050400 Supported Supported Nucleoplasm
Cytosol Endometrial cancer:4.97e-4 (unfavourable), Liver cancer:5.24e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 115.1 NICN1 MGC12936 ENSG00000145029 Nicolin 1 3 49422946-49429326 Predicted intracellular proteins Evidence at protein level HPA037550, HPA058014 Uncertain Supported Nucleoplasm Renal cancer:8.81e-7 (favourable), Pancreatic cancer:1.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 32.0 NID1 entactin, NID ENSG00000116962 Nidogen 1 1 235975830-236065162 Plasma proteins, Predicted secreted proteins Evidence at protein level CAB010044 Approved Renal cancer:5.38e-8 (unfavourable) Expressed in all Expressed in all placenta: 323.7 NIF3L1 ALS2CR1, CALS-7, MDS015 ENSG00000196290 NIF3 NGG1 interacting factor 3-like 1 2 200889327-200903930 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036335, HPA036336, HPA061466 Supported Approved Vesicles Liver cancer:2.51e-6 (unfavourable), Endometrial cancer:9.52e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 39.8 NIFK hNIFK, MKI67IP, Nopp34 ENSG00000155438 Nucleolar protein interacting with the FHA domain of MKI67 2 121726945-121736923 Predicted intracellular proteins Evidence at protein level CAB015382, HPA035735, HPA035736, CAB075728, CAB075729 Supported Validated Nucleoli Renal cancer:5.01e-11 (unfavourable), Liver cancer:2.92e-6 (unfavourable), Endometrial cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all lymph node: 50.3 NINJ1 NIN1 ENSG00000131669 Ninjurin 1 9 93121489-93134288 Predicted membrane proteins Evidence at protein level HPA045063 Uncertain Expressed in all Expressed in all bone marrow: 158.5 NIP7 CGI-37, FLJ10296, HSPC031, KD93 ENSG00000132603 NIP7, nucleolar pre-rRNA processing protein 16 69339430-69343111 Predicted intracellular proteins Evidence at protein level HPA040856, HPA059850 Supported Supported Nucleus
Nucleoli Pancreatic cancer:6.69e-5 (unfavourable), Head and neck cancer:1.52e-4 (unfavourable) Expressed in all Expressed in all lymph node: 23.3 NIPA2 ENSG00000140157 Non imprinted in Prader-Willi/Angelman syndrome 2 15 22838641-22868384 Predicted membrane proteins, Transporters Evidence at protein level HPA067160, HPA071342 Approved Approved Golgi apparatus Expressed in all Expressed in all appendix: 45.7 NIPAL3 DJ462O23.2, NPAL3 ENSG00000001461 NIPA-like domain containing 3 1 24415794-24472976 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039978 Approved Approved Nucleoplasm Renal cancer:3.03e-7 (favourable), Thyroid cancer:3.95e-4 (favourable) Expressed in all Expressed in all prostate: 94.7 NIPBL DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2 ENSG00000164190 Nipped-B homolog (Drosophila) 5 36876759-37066413 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040834, HPA058239 Approved Supported Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 55.9 NIPSNAP1 ENSG00000184117 Nipsnap homolog 1 (C. elegans) 22 29554808-29581337 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059227 Uncertain Renal cancer:8.82e-6 (favourable) Expressed in all Expressed in all liver: 134.2 NIPSNAP3A DKFZp564D177, FLJ13953, HSPC299, MGC14553 ENSG00000136783 Nipsnap homolog 3A (C. elegans) 9 104747688-104760122 Predicted intracellular proteins Evidence at protein level HPA042491 Approved Expressed in all Expressed in all adrenal gland: 51.1 NISCH I-1, IRAS, KIAA0975 ENSG00000010322 Nischarin 3 52455118-52493071 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA023189 Approved Pancreatic cancer:1.91e-4 (favourable) Expressed in all Expressed in all testis: 96.0 NIT1 ENSG00000158793 Nitrilase 1 1 161118086-161125445 Predicted intracellular proteins Evidence at protein level HPA006657 Approved Renal cancer:4.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.7 NKIRAS1 kappaB-Ras1, KBRAS1 ENSG00000197885 NFKB inhibitor interacting Ras-like 1 3 23891660-23946591 Predicted intracellular proteins Evidence at protein level HPA062521 Approved Microtubules Renal cancer:7.71e-13 (favourable), Lung cancer:3.69e-4 (favourable), Endometrial cancer:8.31e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 50.5 NKIRAS2 DKFZP434N1526, kappaB-Ras2, KBRAS2 ENSG00000168256 NFKB inhibitor interacting Ras-like 2 17 42011382-42025644 Predicted intracellular proteins Evidence at protein level HPA062861 Approved Nucleus
Nucleoli Renal cancer:1.23e-4 (unfavourable), Liver cancer:5.56e-4 (unfavourable) Expressed in all Expressed in all placenta: 49.2 NKTR p104 ENSG00000114857 Natural killer cell triggering receptor 3 42600614-42648741 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022120, HPA051576 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:1.05e-5 (favourable), Head and neck cancer:1.26e-4 (favourable), Renal cancer:5.02e-4 (unfavourable), Prostate cancer:6.01e-4 (unfavourable) Expressed in all Expressed in all testis: 24.3 NLE1 FLJ10458 ENSG00000073536 Notchless homolog 1 (Drosophila) 17 35128753-35142315 Predicted intracellular proteins Evidence at protein level HPA018807 Approved Supported Nucleus
Nucleoli Liver cancer:8.64e-8 (unfavourable), Urothelial cancer:6.39e-4 (unfavourable) Expressed in all Expressed in all ovary: 15.8 NLK ENSG00000087095 Nemo-like kinase 17 28041737-28196381 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018192, HPA056511 Approved Supported Nucleus
Nucleoli
Cell Junctions Expressed in all Expressed in all cerebral cortex: 52.5 NLRX1 CLR11.3, NOD9 ENSG00000160703 NLR family member X1 11 119166568-119184016 Predicted intracellular proteins Evidence at protein level HPA061516 Supported Supported Plasma membrane
Cell Junctions
Mitochondria Renal cancer:2.59e-6 (favourable), Endometrial cancer:2.47e-5 (favourable) Expressed in all Expressed in all esophagus: 37.9 NMD3 CGI-07 ENSG00000169251 NMD3 ribosome export adaptor 3 161104696-161253532 Predicted intracellular proteins Evidence at protein level HPA035019 Supported Nucleus
Nucleoli Pancreatic cancer:2.03e-5 (unfavourable) Expressed in all Expressed in all prostate: 43.8 NME1 NDPKA, NM23, NM23-H1 ENSG00000239672 NME/NM23 nucleoside diphosphate kinase 1 17 51153536-51162428 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008467, CAB040571, HPA041113 Supported Validated Nucleoplasm
Cytosol Renal cancer:2.07e-9 (unfavourable), Liver cancer:2.60e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 89.5 NME1-NME2 NM23-LV, NMELV ENSG00000011052 NME1-NME2 readthrough 17 51153590-51171744 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002169, HPA008467, HPA041113 Approved Supported Cytosol Glioma:8.99e-4 (favourable) Expressed in all Expressed in all appendix: 50.0 NME2 NDPKB, NM23-H2 ENSG00000243678 NME/NM23 nucleoside diphosphate kinase 2 17 51165435-51171747 Predicted intracellular proteins Evidence at protein level HPA041113 Approved Renal cancer:1.55e-6 (unfavourable), Cervical cancer:4.74e-4 (unfavourable), Liver cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all breast: 509.0 NME3 DR-nm23, NDPKC, NM23-H3 ENSG00000103024 NME/NM23 nucleoside diphosphate kinase 3 16 1770286-1771730 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041113, HPA052733 Approved Approved Nucleoplasm
Cytosol Breast cancer:6.81e-5 (favourable) Expressed in all Expressed in all adrenal gland: 36.2 NME4 NDPKD, nm23-H4, NM23H4 ENSG00000103202 NME/NM23 nucleoside diphosphate kinase 4 16 396725-410367 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB045997, HPA072588 Approved Supported Mitochondria Renal cancer:1.61e-7 (unfavourable), Cervical cancer:6.53e-4 (unfavourable) Expressed in all Expressed in all prostate: 161.0 NME6 IPIA-ALPHA, NM23-H6 ENSG00000172113 NME/NM23 nucleoside diphosphate kinase 6 3 48293264-48301685 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017909 Approved Approved Vesicles Liver cancer:2.17e-7 (unfavourable), Renal cancer:3.18e-5 (favourable) Expressed in all Expressed in all fallopian tube: 27.5 NME7 CFAP67, FLJ37194, NM23-H7 ENSG00000143156 NME/NM23 family member 7 1 169132531-169367967 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038014, HPA054289 Uncertain Approved Mitochondria Liver cancer:3.24e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 38.6 NMI ENSG00000123609 N-myc (and STAT) interactor 2 151270465-151290057 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008588 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.57e-7 (unfavourable), Liver cancer:1.15e-4 (unfavourable), Pancreatic cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all spleen: 47.7 NMRK1 bA235O14.2, C9orf95, FLJ20559, NRK1 ENSG00000106733 Nicotinamide riboside kinase 1 9 75060573-75088217 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049795 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:3.70e-6 (favourable), Renal cancer:5.60e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 118.5 NMT1 NMT ENSG00000136448 N-myristoyltransferase 1 17 45051610-45109016 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022949, HPA022963 Supported Supported Plasma membrane
Cytosol Liver cancer:4.94e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 58.8 NMT2 ENSG00000152465 N-myristoyltransferase 2 10 15102584-15168693 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001303 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 39.2 NNT ENSG00000112992 Nicotinamide nucleotide transhydrogenase 5 43602692-43707405 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004829, CAB004975 Supported Validated Mitochondria Renal cancer:1.22e-15 (favourable) Expressed in all Expressed in all heart muscle: 139.6 NOA1 C4orf14, hAtNOS1, hNOA1, MGC3232, MTG3 ENSG00000084092 Nitric oxide associated 1 4 56963370-56978823 Predicted secreted proteins Evidence at protein level HPA035838, HPA035839 Approved Supported Mitochondria Renal cancer:2.38e-4 (favourable) Expressed in all Expressed in all fallopian tube: 16.8 NOB1 ART-4, MST158, NOB1P, PSMD8BP1 ENSG00000141101 NIN1/RPN12 binding protein 1 homolog 16 69741867-69754940 Predicted intracellular proteins Evidence at protein level HPA041522, HPA049430, HPA067411 Approved Approved Focal adhesion sites
Cytosol Head and neck cancer:4.21e-5 (unfavourable), Liver cancer:8.16e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 69.0 NOC2L DKFZP564C186, NET15, NET7, NIR, PPP1R112 ENSG00000188976 NOC2-like nucleolar associated transcriptional repressor 1 944204-959309 Predicted intracellular proteins Evidence at protein level HPA044258, HPA062195 Approved Validated Nucleoli Expressed in all Expressed in all skin: 42.1 NOC3L AD24, C10orf117, FAD24, FLJ12820 ENSG00000173145 NOC3-like DNA replication regulator 10 94333226-94362959 Predicted intracellular proteins Evidence at protein level HPA063958, HPA067638, HPA070981 Validated Nucleus
Nucleoli Expressed in all Expressed in all testis: 19.1 NOC4L MGC3162, NET49, UTP19 ENSG00000184967 Nucleolar complex associated 4 homolog 12 132144448-132152473 Predicted intracellular proteins Evidence at protein level HPA053424 Supported Nucleus
Nucleoli Expressed in all Expressed in all testis: 24.8 NOL10 FLJ14075, PQBP5 ENSG00000115761 Nucleolar protein 10 2 10570766-10689987 Predicted intracellular proteins Evidence at protein level HPA035286, HPA043075 Approved Supported Nucleoli Liver cancer:1.43e-7 (unfavourable), Endometrial cancer:2.92e-5 (unfavourable), Renal cancer:7.51e-5 (unfavourable) Expressed in all Expressed in all testis: 27.8 NOL11 DKFZP586L0724 ENSG00000130935 Nucleolar protein 11 17 67717833-67744531 Predicted intracellular proteins Evidence at protein level HPA022010 Approved Validated Nucleoli Colorectal cancer:1.00e-6 (favourable), Liver cancer:2.59e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.0 NOL12 MGC3731, Nop25, RRP17 ENSG00000273899 Nucleolar protein 12 22 37681673-37693478 Predicted intracellular proteins Evidence at protein level HPA003547 Uncertain Approved Nucleus
Nucleoli
Vesicles Renal cancer:2.56e-6 (unfavourable), Cervical cancer:6.80e-5 (favourable), Urothelial cancer:3.24e-4 (favourable), Lung cancer:9.41e-4 (favourable) Expressed in all Expressed in all adrenal gland: 25.2 NOL6 bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838, Nrap, UTP22 ENSG00000165271 Nucleolar protein 6 (RNA-associated) 9 33461441-33473930 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055891, HPA061002 Supported Validated Nucleus
Nucleoli
Mitochondria Liver cancer:4.83e-5 (unfavourable), Thyroid cancer:9.49e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.1 NOL7 C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1 ENSG00000225921 Nucleolar protein 7, 27kDa 6 13615327-13632739 Predicted intracellular proteins Evidence at protein level HPA029185, HPA049693 Supported Validated Nucleus
Nucleoli
Mitochondria Ovarian cancer:3.64e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 91.5 NOL8 C9orf34, FLJ20736, Nop132 ENSG00000198000 Nucleolar protein 8 9 92297358-92325636 Predicted intracellular proteins Evidence at protein level HPA044440, HPA062922 Uncertain Supported Nucleoli Renal cancer:1.02e-5 (unfavourable), Liver cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 24.0 NOLC1 KIAA0035, NOPP130, NOPP140, P130 ENSG00000166197 Nucleolar and coiled-body phosphoprotein 1 10 102152176-102163871 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032654, HPA037366, HPA050388 Supported Validated Nucleoli Thyroid cancer:8.25e-5 (unfavourable), Renal cancer:9.19e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 68.0 NOMO2 NOMO, PM5 ENSG00000185164 NODAL modulator 2 16 18417325-18562211 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046697, HPA061174 Approved Expressed in all Expressed in all parathyroid gland: 154.9 NONO NMT55, NRB54, P54, P54NRB, PPP1R114 ENSG00000147140 Non-POU domain containing, octamer-binding X 71283192-71301168 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB022069, HPA054094, HPA054559 Supported Validated Nucleoplasm Endometrial cancer:9.29e-4 (unfavourable) Expressed in all Expressed in all ovary: 245.1 NOP10 MGC70651, NOLA3, NOP10P ENSG00000182117 NOP10 ribonucleoprotein 15 34341713-34343177 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA059198 Supported Supported Nuclear bodies Endometrial cancer:1.48e-5 (favourable) Expressed in all Expressed in all epididymis: 284.1 NOP14 C4orf9, NOL14, RES4-25, UTP2 ENSG00000087269 NOP14 nucleolar protein 4 2937933-2963385 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039596, HPA055652 Approved Validated Nucleus
Nucleoli Colorectal cancer:3.93e-5 (favourable), Liver cancer:9.10e-4 (unfavourable) Expressed in all Expressed in all lymph node: 27.6 NOP16 HSPC111, HSPC185, LOC51491 ENSG00000048162 NOP16 nucleolar protein 5 176383938-176388975 Predicted intracellular proteins Evidence at protein level HPA036506, HPA058147 Approved Validated Nucleoli Renal cancer:5.75e-6 (unfavourable), Liver cancer:5.14e-4 (unfavourable) Expressed in all Expressed in all appendix: 26.8 NOP2 NOL1, NOP120, NSUN1, p120 ENSG00000111641 NOP2 nucleolar protein 12 6556863-6568691 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040119 Supported Supported Nucleoli Renal cancer:2.35e-10 (unfavourable), Liver cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all lymph node: 36.1 NOP56 NOL5A, SCA36 ENSG00000101361 NOP56 ribonucleoprotein 20 2652145-2658393 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049918, CAB075757 Supported Validated Nucleoli fibrillar center Renal cancer:2.22e-16 (unfavourable), Liver cancer:1.59e-7 (unfavourable), Endometrial cancer:1.24e-4 (unfavourable), Melanoma:6.77e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 59.6 NOP58 HSPC120, NOP5 ENSG00000055044 NOP58 ribonucleoprotein 2 202265716-202303666 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018472, HPA021062 Supported Validated Nucleus
Nucleoli fibrillar center Renal cancer:3.38e-9 (unfavourable), Liver cancer:1.97e-6 (unfavourable), Ovarian cancer:9.86e-4 (favourable) Expressed in all Expressed in all lymph node: 70.2 NOP9 C14orf21 ENSG00000196943 NOP9 nucleolar protein 14 24299862-24309124 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000850 Approved Nucleus
Nucleoli
Cytosol Renal cancer:9.39e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 28.8 NOSIP CGI-25 ENSG00000142546 Nitric oxide synthase interacting protein 19 49555711-49590262 Predicted intracellular proteins Evidence at protein level HPA043464, HPA062132 Approved Validated Nucleus Expressed in all Expressed in all testis: 97.8 NOTCH1 TAN1 ENSG00000148400 Notch 1 9 136494444-136545862 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB008112, CAB022466, HPA067168 Supported Approved Nucleoplasm Renal cancer:5.45e-4 (unfavourable) Expressed in all Expressed in all skin: 24.0 NOTCH2 ENSG00000134250 Notch 2 1 119911553-120069626 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046392, HPA048743 Uncertain Supported Nucleoplasm
Plasma membrane Ovarian cancer:5.24e-4 (unfavourable), Pancreatic cancer:9.48e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 46.5 NOTCH2NL N2N ENSG00000264343 Notch 2 N-terminal like 1 146146203-146229026 Predicted intracellular proteins Evidence at protein level CAB004669, HPA046392 Uncertain Not detected Expressed in all testis: 41.4 NOXA1 FLJ25475, NY-CO-31, SDCCAG31 ENSG00000188747 NADPH oxidase activator 1 9 137423350-137434406 Predicted intracellular proteins Evidence at protein level HPA044781 Uncertain Approved Vesicles Renal cancer:2.65e-4 (favourable) Expressed in all Expressed in all skin: 21.5 NPC1 ENSG00000141458 Niemann-Pick disease, type C1 18 23506184-23586898 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA026618, CAB070132 Approved Liver cancer:2.26e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 110.9 NPDC1 CAB-, CAB1, DKFZp586J0523 ENSG00000107281 Neural proliferation, differentiation and control, 1 9 137039470-137046203 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008189 Approved Approved Nucleus
Cytosol Colorectal cancer:2.01e-5 (unfavourable), Endometrial cancer:6.19e-5 (favourable), Pancreatic cancer:3.18e-4 (favourable) Expressed in all Expressed in all prostate: 108.1 NPEPL1 bA261P9.2, FLJ11583 ENSG00000215440 Aminopeptidase-like 1 20 58689131-58719238 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004986, CAB017025, HPA036356 Approved Approved Nucleoplasm Renal cancer:1.87e-9 (unfavourable), Urothelial cancer:5.73e-4 (favourable) Expressed in all Expressed in all spleen: 25.2 NPEPPS MP100, PSA ENSG00000141279 Aminopeptidase puromycin sensitive 17 47522942-47623276 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021453, HPA045649 Uncertain Supported Cytosol Colorectal cancer:3.39e-5 (favourable), Liver cancer:3.67e-5 (unfavourable) Expressed in all Expressed in all esophagus: 107.3 NPIPA7 ENSG00000214967 Nuclear pore complex interacting protein family, member A7 16 16379055-16393954 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Not detected Expressed in all parathyroid gland: 48.7 NPIPB3 KIAA0220, NPIPL3 ENSG00000169246 Nuclear pore complex interacting protein family, member B3 16 21402237-21448567 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Expressed in all skin: 229.8 NPIPB4 ENSG00000185864 Nuclear pore complex interacting protein family, member B4 16 21834569-21880827 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Expressed in all skin: 125.9 NPIPB5 ENSG00000243716 Nuclear pore complex interacting protein family, member B5 16 22479121-22536521 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Approved Nucleoplasm Mixed Expressed in all skin: 271.1 NPLOC4 FLJ20657, KIAA1499, NPL4 ENSG00000182446 NPL4 homolog, ubiquitin recognition factor 17 81556887-81648465 Predicted intracellular proteins, Transporters Evidence at protein level HPA021560, HPA023295 Supported Supported Nucleoplasm
Cytosol Renal cancer:6.95e-7 (unfavourable), Liver cancer:1.16e-5 (unfavourable) Expressed in all Expressed in all testis: 67.9 NPM1 B23, NPM ENSG00000181163 Nucleophosmin (nucleolar phosphoprotein B23, numatrin) 5 171387116-171411137 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA011384, CAB012983 Supported Validated Nucleus
Nucleoli Renal cancer:2.89e-6 (unfavourable), Liver cancer:4.82e-6 (unfavourable), Head and neck cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all ovary: 1797.0 NPM3 ENSG00000107833 Nucleophosmin/nucleoplasmin 3 10 101781325-101783413 Predicted intracellular proteins Evidence at protein level HPA036295, HPA036296 Approved Approved Nucleoli
Actin filaments
Cytosol Head and neck cancer:1.42e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 28.4 NPRL2 NPR2, NPR2L, TUSC4 ENSG00000114388 NPR2-like, GATOR1 complex subunit 3 50347330-50351091 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038196, HPA038197 Approved Supported Cytosol Lung cancer:1.59e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 13.5 NPRL3 C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11 ENSG00000103148 NPR3-like, GATOR1 complex subunit 16 84271-138860 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA011741 Uncertain Approved Cytosol Expressed in all Expressed in all parathyroid gland: 24.5 NPTN GP55, GP65, np55, np65, SDFR1, SDR1 ENSG00000156642 Neuroplastin 15 73560014-73634134 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051497, HPA072453 Approved Approved Cytokinetic bridge
Mitochondria Expressed in all Expressed in all smooth muscle: 428.0 NQO2 DHQV, DIA6, NMOR2, QR2 ENSG00000124588 NAD(P)H dehydrogenase, quinone 2 6 2987987-3028869 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021283, HPA021332 Supported Supported Nucleoplasm
Cytosol Liver cancer:8.40e-4 (unfavourable) Expressed in all Expressed in all kidney: 201.3 NR1D2 BD73, EAR-1r, Hs.37288, HZF2, RVR ENSG00000174738 Nuclear receptor subfamily 1, group D, member 2 3 23945260-23980618 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053868, HPA054798 Approved Approved Nucleoplasm Renal cancer:4.47e-7 (favourable) Expressed in all Expressed in all thyroid gland: 89.9 NR1H2 LXR-b, NER, NER-I, RIP15, UNR ENSG00000131408 Nuclear receptor subfamily 1, group H, member 2 19 50329653-50382982 Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056838, HPA070212 Uncertain Approved Nucleoplasm Colorectal cancer:9.86e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 87.8 NR1H3 LXR-a, RLD-1 ENSG00000025434 Nuclear receptor subfamily 1, group H, member 3 11 47248300-47269032 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA036443, CAB037109 Approved Renal cancer:1.40e-5 (unfavourable), Urothelial cancer:3.40e-4 (favourable), Endometrial cancer:5.05e-4 (favourable), Liver cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 55.1 NR2C2 hTAK1, TAK1, TR2R1, TR4 ENSG00000177463 Nuclear receptor subfamily 2, group C, member 2 3 14947584-15053600 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006313 Approved Validated Nucleoplasm Head and neck cancer:1.51e-5 (favourable) Expressed in all Expressed in all testis: 38.8 NR2C2AP TRA16 ENSG00000184162 Nuclear receptor 2C2-associated protein 19 19201416-19203424 Predicted intracellular proteins Evidence at protein level HPA042054, HPA055653 Approved Validated Nucleoplasm Liver cancer:5.63e-5 (unfavourable), Thyroid cancer:1.65e-4 (favourable), Colorectal cancer:8.53e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 23.9 NR3C1 GR, GRL ENSG00000113580 Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 5 143277931-143435512 Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004248, CAB010435 Supported Validated Nucleoplasm
Mitochondria
Cytosol Renal cancer:1.72e-6 (unfavourable), Endometrial cancer:3.64e-5 (unfavourable) Expressed in all Expressed in all placenta: 66.4 NR4A1 GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3 ENSG00000123358 Nuclear receptor subfamily 4, group A, member 1 12 52022832-52059507 Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059742 Supported Nucleus
Cytosol Renal cancer:6.99e-4 (favourable) Expressed in all Expressed in all adrenal gland: 753.5 NRAS N-ras ENSG00000213281 Neuroblastoma RAS viral (v-ras) oncogene homolog 1 114704469-114716894 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010157, HPA049830 Uncertain Liver cancer:3.03e-7 (unfavourable), Pancreatic cancer:1.36e-4 (unfavourable), Renal cancer:7.87e-4 (unfavourable) Expressed in all Expressed in all placenta: 39.1 NRBF2 COPR1, COPR2, DKFZp564C1664, FLJ30395 ENSG00000148572 Nuclear receptor binding factor 2 10 63133247-63155031 Predicted intracellular proteins Evidence at protein level HPA021670, HPA059477 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:2.36e-4 (unfavourable) Expressed in all Expressed in all spleen: 30.9 NRBP1 BCON3, MADM, MUDPNP, NRBP ENSG00000115216 Nuclear receptor binding protein 1 2 27427790-27442259 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029527, CAB033078 Supported Supported Cytosol Liver cancer:2.22e-5 (unfavourable), Renal cancer:5.84e-5 (unfavourable) Expressed in all Expressed in all testis: 125.5 NRBP2 DKFZp434P086 ENSG00000185189 Nuclear receptor binding protein 2 8 143833594-143840974 Enzymes, Predicted intracellular proteins Evidence at protein level CAB020944, HPA029051, HPA029052 Approved Approved Cytosol Renal cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 55.4 NRD1 hNRD1, hNRD2 ENSG00000078618 Nardilysin (N-arginine dibasic convertase) 1 51789191-51878937 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053661 Approved Nucleoplasm Renal cancer:2.12e-9 (unfavourable), Liver cancer:5.49e-6 (unfavourable) Expressed in all Expressed in all testis: 167.1 NREP C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17 ENSG00000134986 Neuronal regeneration related protein 5 111662621-111997464 Predicted intracellular proteins Evidence at protein level HPA000545 Approved Approved Vesicles Stomach cancer:3.09e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 175.6 NRF1 ALPHA-PAL, EWG ENSG00000106459 Nuclear respiratory factor 1 7 129611714-129757082 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029329 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.02e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 20.7 NRIP1 RIP140 ENSG00000180530 Nuclear receptor interacting protein 1 21 14961235-15065000 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046571, HPA060036 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all cervix, uterine: 38.8 NRP1 CD304, NRP, VEGF165R ENSG00000099250 Neuropilin 1 10 33177492-33336262 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB004511, HPA030278 Approved Uncertain Mitochondria Stomach cancer:1.22e-5 (unfavourable), Cervical cancer:7.10e-5 (unfavourable), Renal cancer:3.87e-4 (unfavourable), Glioma:7.78e-4 (unfavourable) Expressed in all Expressed in all placenta: 193.5 NSA2 FLJ94393, HCLG1, HUSSY-29, TINP1 ENSG00000164346 NSA2 ribosome biogenesis homolog 5 74766991-74780113 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043487 Approved Supported Nucleus
Nucleoli Expressed in all Expressed in all ovary: 74.4 NSD1 ARA267, FLJ22263, KMT3B, STO ENSG00000165671 Nuclear receptor binding SET domain protein 1 5 177133025-177300215 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA048431, HPA070333 Supported Nucleus
Plasma membrane Expressed in all Expressed in all testis: 43.2 NSDHL H105e3, SDR31E1, XAP104 ENSG00000147383 NAD(P) dependent steroid dehydrogenase-like X 152830967-152869729 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000248, HPA000571 Supported Validated Endoplasmic reticulum
Lipid droplets Renal cancer:6.09e-5 (favourable), Liver cancer:5.04e-4 (unfavourable), Cervical cancer:5.65e-4 (favourable) Expressed in all Expressed in all epididymis: 53.2 NSFL1C dJ776F14.1, p47, UBX1, UBXD10, UBXN2C ENSG00000088833 NSFL1 (p97) cofactor (p47) 20 1442162-1473842 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047108, HPA050628 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 35.2 NSL1 C1orf48, DC8, DKFZP566O1646, MIS14 ENSG00000117697 NSL1, MIS12 kinetochore complex component 1 212726153-212791782 Predicted intracellular proteins Evidence at protein level HPA045761, HPA053721 Supported Supported Nucleoplasm
Nuclear speckles
Cytosol Expressed in all Expressed in all cerebral cortex: 35.7 NSMAF FAN ENSG00000035681 Neutral sphingomyelinase (N-SMase) activation associated factor 8 58583504-58659844 Predicted intracellular proteins Evidence at protein level HPA023067, HPA023148, HPA023151 Uncertain Approved Nucleoli Renal cancer:4.61e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.0 NSMCE1 NSE1 ENSG00000169189 NSE1 homolog, SMC5-SMC6 complex component 16 27224991-27268794 Predicted intracellular proteins Evidence at protein level HPA041567, HPA043091 Supported Supported Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 121.1 NSMCE2 C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7 ENSG00000156831 NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase 8 125091679-125367120 Predicted intracellular proteins Evidence at protein level HPA051614, HPA065734 Supported Supported Nucleus
Nuclear bodies Liver cancer:7.54e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 29.9 NSMCE4A bA500G22.3, C10orf86, FLJ20003, NSE4A ENSG00000107672 NSE4 homolog A, SMC5-SMC6 complex component 10 121957088-121975217 Predicted intracellular proteins Evidence at protein level HPA037459, HPA038412, HPA044872 Approved Validated Nucleoplasm Lung cancer:2.72e-5 (favourable), Renal cancer:2.45e-4 (unfavourable) Expressed in all Expressed in all prostate: 35.0 NSMF NELF ENSG00000165802 NMDA receptor synaptonuclear signaling and neuronal migration factor 9 137447570-137459334 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044316 Approved Supported Nucleoplasm Renal cancer:1.85e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 195.4 NSRP1 CCDC55, DKFZP434K1421, NSrp70 ENSG00000126653 Nuclear speckle splicing regulatory protein 1 17 30115521-30186475 Predicted intracellular proteins Evidence at protein level HPA015593, HPA015603 Supported Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 45.1 NSUN2 FLJ20303, Misu, MRT5, TRM4 ENSG00000037474 NOP2/Sun RNA methyltransferase family, member 2 5 6599239-6633291 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037896 Supported Supported Nucleus Renal cancer:5.69e-5 (unfavourable) Expressed in all Expressed in all breast: 43.6 NSUN5 FLJ10267, NOL1R, NSUN5A, p120(NOL1), WBSCR20, WBSCR20A, Ynl022cL ENSG00000130305 NOP2/Sun domain family, member 5 7 73302517-73308867 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020536, HPA045590, HPA046867 Approved Validated Nucleus
Nucleoli Glioma:2.11e-4 (unfavourable), Liver cancer:3.96e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 26.0 NSUN6 ARL5B-AS1, FLJ23743, NOPD1 ENSG00000241058 NOP2/Sun domain family, member 6 10 18545561-18659285 Predicted intracellular proteins Evidence at protein level HPA045902 Approved Approved Golgi apparatus Renal cancer:5.55e-5 (unfavourable), Lung cancer:8.42e-4 (favourable) Expressed in all Expressed in all liver: 30.7 NT5C cdN, DNT-1, DNT1, PN-I, UMPH2 ENSG00000125458 5', 3'-nucleotidase, cytosolic 17 75130225-75131795 Predicted intracellular proteins Evidence at protein level HPA021581, HPA023632 Approved Supported Cytosol Liver cancer:3.05e-4 (unfavourable), Urothelial cancer:7.66e-4 (favourable) Expressed in all Expressed in all small intestine: 32.0 NT5C2 cN-II, GMP, NT5B, PNT5, SPG65 ENSG00000076685 5'-nucleotidase, cytosolic II 10 103088017-103193306 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003751 Approved Expressed in all Expressed in all thyroid gland: 118.9 NT5C3A cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1 ENSG00000122643 5'-nucleotidase, cytosolic IIIA 7 33014114-33062797 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA010630, HPA029058 Uncertain Renal cancer:1.70e-4 (unfavourable), Liver cancer:2.42e-4 (unfavourable) Expressed in all Expressed in all rectum: 47.0 NT5C3B MGC20781, NT5C3L ENSG00000141698 5'-nucleotidase, cytosolic IIIB 17 41825181-41836263 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030786, HPA057095 Approved Liver cancer:8.11e-5 (unfavourable), Pancreatic cancer:2.67e-4 (favourable) Expressed in all Expressed in all thyroid gland: 79.0 NT5DC1 dJ486I3.1, MGC24302, NT5C2L1 ENSG00000178425 5'-nucleotidase domain containing 1 6 116100849-116249497 Predicted intracellular proteins Evidence at protein level HPA030352 Uncertain Renal cancer:7.49e-7 (favourable), Colorectal cancer:2.61e-4 (favourable) Expressed in all Expressed in all thyroid gland: 47.1 NT5DC2 FLJ12442 ENSG00000168268 5'-nucleotidase domain containing 2 3 52524385-52535054 Predicted intracellular proteins Evidence at protein level HPA050683 Approved Liver cancer:2.16e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 96.5 NTAN1 ENSG00000157045 N-terminal asparagine amidase 16 15037853-15056079 Predicted intracellular proteins Evidence at protein level HPA051418 Approved Nucleoplasm
Golgi apparatus Glioma:8.85e-4 (unfavourable), Stomach cancer:9.07e-4 (unfavourable) Expressed in all Expressed in all epididymis: 19.9 NTHL1 NTH1, OCTS3 ENSG00000065057 Nth-like DNA glycosylase 1 16 2039815-2047866 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB025152 Supported Expressed in all Expressed in all fallopian tube: 21.1 NTMT1 AD-003, C9orf32, HOMT1A, METTL11A ENSG00000148335 N-terminal Xaa-Pro-Lys N-methyltransferase 1 9 129608884-129636131 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020092, HPA058420 Uncertain Validated Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 90.4 NUB1 BS4, NUB1L, NYREN18 ENSG00000013374 Negative regulator of ubiquitin-like proteins 1 7 151341699-151378449 Predicted intracellular proteins Evidence at protein level HPA021220, HPA050722, HPA053648 Approved Validated Nucleus
Nucleoli Liver cancer:8.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 106.8 NUBP1 NBP1, NBP35 ENSG00000103274 Nucleotide binding protein 1 16 10743786-10769351 Predicted intracellular proteins Evidence at protein level HPA041656, HPA041799 Supported Supported Cytosol Renal cancer:7.61e-8 (favourable), Cervical cancer:2.81e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 54.3 NUBP2 CFD1 ENSG00000095906 Nucleotide binding protein 2 16 1782901-1789191 Predicted intracellular proteins Evidence at protein level HPA041704 Uncertain Approved Nucleus
Cytosol Renal cancer:9.63e-5 (favourable) Expressed in all Expressed in all spleen: 17.8 NUBPL C14orf127, FLJ12660, huInd1, IND1 ENSG00000151413 Nucleotide binding protein-like 14 31489956-31861224 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029203 Approved Approved Mitochondria Renal cancer:3.64e-8 (favourable) Expressed in all Expressed in all breast: 30.3 NUCB1 Calnuc, NUC ENSG00000104805 Nucleobindin 1 19 48900050-48923372 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA008176 Supported Supported Golgi apparatus
Microtubules Expressed in all Expressed in all parathyroid gland: 224.3 NUCB2 NEFA ENSG00000070081 Nucleobindin 2 11 17208153-17349974 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008395, CAB015931 Approved Validated Golgi apparatus Endometrial cancer:8.27e-6 (favourable), Renal cancer:3.94e-5 (unfavourable), Ovarian cancer:1.98e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 719.8 NUCKS1 NUCKS ENSG00000069275 Nuclear casein kinase and cyclin-dependent kinase substrate 1 1 205712819-205750276 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062351, HPA063843 Supported Supported Nucleus
Nucleoli Endometrial cancer:1.41e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 179.8 NUDC NudC ENSG00000090273 NudC nuclear distribution protein 1 26900238-26946862 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027183, HPA028105 Supported Validated Cytosol Liver cancer:1.21e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 149.4 NUDCD2 DKFZp686E10109 ENSG00000170584 NudC domain containing 2 5 163446526-163460140 Predicted intracellular proteins Evidence at protein level HPA037384, HPA037385 Uncertain Supported Microtubules
Cytosol Colorectal cancer:2.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.7 NUDT1 MTH1 ENSG00000106268 Nudix (nucleoside diphosphate linked moiety X)-type motif 1 7 2242222-2251146 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA012636 Approved Approved Cytosol Renal cancer:1.30e-7 (unfavourable), Liver cancer:4.44e-4 (unfavourable) Expressed in all Expressed in all testis: 50.7 NUDT14 UGPP ENSG00000183828 Nudix (nucleoside diphosphate linked moiety X)-type motif 14 14 105172938-105181323 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046755, HPA058759 Approved Approved Nucleoli
Microtubules Renal cancer:1.18e-5 (favourable), Ovarian cancer:1.66e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.8 NUDT15 FLJ10956, MTH2 ENSG00000136159 Nudix (nucleoside diphosphate linked moiety X)-type motif 15 13 48037567-48047222 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038968, HPA038969 Approved Supported Nucleoplasm Melanoma:1.25e-5 (unfavourable) Expressed in all Expressed in all prostate: 23.9 NUDT16 FLJ31265 ENSG00000198585 Nudix (nucleoside diphosphate linked moiety X)-type motif 16 3 131381671-131388830 Enzymes, Predicted intracellular proteins Evidence at protein level HPA060452, HPA062492 Uncertain Supported Nucleus
Nucleoli Renal cancer:1.05e-7 (favourable), Cervical cancer:9.39e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 54.4 NUDT16L1 SDOS ENSG00000168101 Nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 16 4693694-4695859 Predicted intracellular proteins Evidence at protein level HPA044186, HPA063605 Approved Approved Plasma membrane
Cytosol Renal cancer:1.02e-6 (favourable), Lung cancer:2.79e-4 (favourable) Expressed in all Expressed in all prostate: 28.4 NUDT19 RP2 ENSG00000213965 Nudix (nucleoside diphosphate linked moiety X)-type motif 19 19 32691961-32713796 Predicted secreted proteins Evidence at protein level HPA042761 Uncertain Nucleus
Nucleoli
Cytosol Urothelial cancer:1.35e-4 (favourable) Expressed in all Expressed in all prostate: 12.4 NUDT2 APAH1 ENSG00000164978 Nudix (nucleoside diphosphate linked moiety X)-type motif 2 9 34329506-34343713 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004684, HPA044903, HPA058623, HPA067639 Uncertain Supported Nucleoplasm Expressed in all Expressed in all epididymis: 42.9 NUDT21 CFIM25, CPSF5 ENSG00000167005 Nudix (nucleoside diphosphate linked moiety X)-type motif 21 16 56429133-56452199 Predicted intracellular proteins Evidence at protein level HPA019863, HPA074228 Uncertain Supported Nuclear bodies
Microtubule organizing center Expressed in all Expressed in all testis: 128.2 NUDT22 MGC13045 ENSG00000149761 Nudix (nucleoside diphosphate linked moiety X)-type motif 22 11 64225941-64230686 Predicted intracellular proteins Evidence at protein level HPA039334, HPA053464 Approved Validated Nucleoplasm Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all duodenum: 32.0 NUDT3 DIPP ENSG00000272325 Nudix (nucleoside diphosphate linked moiety X)-type motif 3 6 34279679-34392674 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047027, HPA055953 Uncertain Approved Cytosol Cervical cancer:5.29e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 77.3 NUDT4 DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487 ENSG00000173598 Nudix (nucleoside diphosphate linked moiety X)-type motif 4 12 93377883-93408146 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017593, HPA047027, HPA057684 Uncertain Approved Cytosol Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all ovary: 191.7 NUDT5 hYSAH1, YSA1H ENSG00000165609 Nudix (nucleoside diphosphate linked moiety X)-type motif 5 10 12165325-12196144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019827 Approved Approved Nucleus
Vesicles
Centrosome Renal cancer:7.14e-12 (unfavourable) Expressed in all Expressed in all liver,thyroid gland: 45.5 NUDT7 ENSG00000140876 Nudix (nucleoside diphosphate linked moiety X)-type motif 7 16 77722492-77742260 Predicted intracellular proteins Evidence at protein level HPA042042 Supported Renal cancer:5.36e-11 (favourable), Head and neck cancer:1.84e-4 (unfavourable) Expressed in all Expressed in all liver: 35.7 NUDT8 FLJ41567 ENSG00000167799 Nudix (nucleoside diphosphate linked moiety X)-type motif 8 11 67627938-67629930 Predicted intracellular proteins Evidence at protein level HPA041252, HPA041466 Supported Approved Nucleoli
Cytosol Renal cancer:3.70e-4 (favourable) Expressed in all Expressed in all heart muscle: 21.0 NUDT9 MGC3037 ENSG00000170502 Nudix (nucleoside diphosphate linked moiety X)-type motif 9 4 87422582-87459454 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036917, HPA044866, HPA078535 Approved Supported Nuclear membrane
Cell Junctions
Mitochondria Renal cancer:8.00e-11 (favourable), Endometrial cancer:7.43e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 84.9 NUFIP2 182-FIP, 82-FIP, FIP-82, KIAA1321, MGC117262, PIG1 ENSG00000108256 Nuclear fragile X mental retardation protein interacting protein 2 17 29255836-29294118 Predicted intracellular proteins Evidence at protein level HPA067443 Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all bone marrow: 53.4 NUMA1 ENSG00000137497 Nuclear mitotic apparatus protein 1 11 72002864-72080693 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019841, HPA019859, HPA029912 Supported Validated Nucleoplasm Renal cancer:7.92e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 243.4 NUMB C14orf41 ENSG00000133961 Numb homolog (Drosophila) 14 73275107-73463642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011478 Approved Approved Cell Junctions
Cytosol Renal cancer:2.32e-6 (favourable) Expressed in all Expressed in all lung: 78.1 NUMBL CAG3A, CTG3a, NUMB-R, NUMBLIKE, NUMBR, TNRC23 ENSG00000105245 Numb homolog (Drosophila)-like 19 40665905-40690972 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058251, HPA058380 Approved Renal cancer:7.55e-15 (unfavourable), Ovarian cancer:1.52e-4 (unfavourable), Colorectal cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 41.8 NUP107 NUP84 ENSG00000111581 Nucleoporin 107kDa 12 68686734-68745809 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA024141, HPA031679 Uncertain Supported Nucleoplasm
Centrosome Liver cancer:3.12e-9 (unfavourable), Renal cancer:1.28e-6 (unfavourable) Expressed in all Expressed in all testis: 38.0 NUP133 FLJ10814 ENSG00000069248 Nucleoporin 133kDa 1 229440260-229508341 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA059767 Approved Supported Nuclear membrane Expressed in all Expressed in all parathyroid gland: 32.5 NUP153 HNUP153 ENSG00000124789 Nucleoporin 153kDa 6 17615035-17706834 Predicted intracellular proteins, Transporters Evidence at protein level HPA027896, HPA027897, HPA027898 Supported Validated Nuclear membrane Expressed in all Expressed in all testis: 53.3 NUP160 FLJ22583, KIAA0197 ENSG00000030066 Nucleoporin 160kDa 11 47778087-47848555 Predicted intracellular proteins, Transporters Evidence at protein level Expressed in all Expressed in all parathyroid gland: 38.8 NUP188 KIAA0169 ENSG00000095319 Nucleoporin 188kDa 9 128947699-129007096 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA061750, HPA063942 Approved Supported Nucleus Endometrial cancer:5.20e-5 (favourable) Expressed in all Expressed in all testis: 104.4 NUP205 C7orf14, KIAA0225 ENSG00000155561 Nucleoporin 205kDa 7 135557919-135648757 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA024574 Uncertain Liver cancer:1.90e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.7 NUP210 FLJ22389, GP210, KIAA0906, POM210 ENSG00000132182 Nucleoporin 210kDa 3 13316235-13420309 Predicted membrane proteins, Transporters Evidence at protein level HPA066888 Approved Liver cancer:6.03e-6 (unfavourable) Expressed in all Expressed in all lymph node: 49.2 NUP214 CAIN, CAN, D9S46E, N214 ENSG00000126883 Nucleoporin 214kDa 9 131125561-131234670 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA048789 Supported Nucleus
Vesicles
Focal adhesion sites Renal cancer:2.39e-5 (favourable) Expressed in all Expressed in all testis: 122.9 NUP35 MP44 ENSG00000163002 Nucleoporin 35kDa 2 183117513-183161680 Predicted intracellular proteins, Transporters Evidence at protein level HPA018401, HPA018410, HPA018441 Supported Supported Nucleoplasm
Nuclear membrane
Plasma membrane Ovarian cancer:3.45e-4 (favourable), Liver cancer:5.02e-4 (unfavourable) Expressed in all Expressed in all testis: 44.7 NUP37 FLJ22618, MGC5585 ENSG00000075188 Nucleoporin 37kDa 12 102073103-102120124 Predicted intracellular proteins, Transporters Evidence at protein level HPA056300, HPA073708 Supported Supported Nucleoplasm Liver cancer:7.70e-6 (unfavourable), Head and neck cancer:6.72e-4 (unfavourable) Expressed in all Expressed in all lymph node: 32.6 NUP43 bA350J20.1, FLJ13287 ENSG00000120253 Nucleoporin 43kDa 6 149724315-149749665 Predicted intracellular proteins, Transporters Evidence at protein level HPA027126, HPA027291, HPA028500 Approved Liver cancer:7.13e-7 (unfavourable), Breast cancer:2.08e-4 (unfavourable) Expressed in all Expressed in all lymph node,thyroid gland: 18.6 NUP50 NPAP60L ENSG00000093000 Nucleoporin 50kDa 22 45163841-45188015 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA047162, HPA048328 Supported Validated Nucleoplasm
Nuclear membrane Stomach cancer:4.06e-4 (favourable) Expressed in all Expressed in all testis: 54.5 NUP54 ENSG00000138750 Nucleoporin 54kDa 4 76114659-76148515 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA035929, HPA058122 Approved Approved Nucleoplasm Liver cancer:4.64e-4 (unfavourable), Colorectal cancer:8.80e-4 (favourable) Expressed in all Expressed in all testis: 38.9 NUP58 KIAA0410, NUP45, NUPL1 ENSG00000139496 Nucleoporin 58kDa 13 25301524-25349800 Predicted intracellular proteins, Transporters Evidence at protein level HPA039360 Approved Approved Plasma membrane
Mitochondria
Cytosol Cervical cancer:2.57e-4 (unfavourable), Liver cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all testis: 86.6 NUP62 DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, p62, SNDI ENSG00000213024 Nucleoporin 62kDa 19 49906825-49929763 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA005435, CAB020724 Supported Supported Nuclear membrane
Vesicles Renal cancer:5.71e-12 (unfavourable), Liver cancer:2.50e-7 (unfavourable) Expressed in all Expressed in all testis: 76.8 NUP85 FLJ12549, NUP75 ENSG00000125450 Nucleoporin 85kDa 17 75205659-75235758 Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA061910, HPA062595 Supported Supported Nucleus
Cytosol Liver cancer:1.73e-7 (unfavourable), Renal cancer:3.32e-6 (unfavourable) Expressed in all Expressed in all testis: 34.1 NUP88 MGC8530 ENSG00000108559 Nucleoporin 88kDa 17 5360963-5420160 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB002209, HPA021816 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 94.1 NUP93 KIAA0095 ENSG00000102900 Nucleoporin 93kDa 16 56730105-56850286 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA017937 Uncertain Liver cancer:1.72e-6 (unfavourable) Expressed in all Expressed in all testis: 74.3 NUP98 NUP96 ENSG00000110713 Nucleoporin 98kDa 11 3671083-3797792 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA074810 Supported Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 150.1 NUPL2 CG1, hCG1, H_RG271G13.9, NLP_1 ENSG00000136243 Nucleoporin like 2 7 23181827-23201011 Predicted intracellular proteins, Transporters Evidence at protein level HPA049036, HPA057251 Validated Nucleus Expressed in all Expressed in all testis: 32.6 NUS1 C6orf68, MGC7199, NgBR, TANGO14 ENSG00000153989 NUS1 dehydrodolichyl diphosphate synthase subunit 6 117675502-117710640 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA027504 Supported Approved Vesicles
Plasma membrane Cervical cancer:6.99e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 91.7 NUTF2 NTF2, PP15 ENSG00000102898 Nuclear transport factor 2 16 67846732-67872567 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040915, HPA040956 Supported Approved Microtubules Head and neck cancer:1.15e-4 (unfavourable), Renal cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 82.6 NUTM2D FAM22D ENSG00000214562 NUT family member 2D 10 87357668-87370695 Predicted intracellular proteins Evidence at protein level HPA064635 Uncertain Nuclear bodies Not detected Expressed in all cerebral cortex: 7.1 NVL ENSG00000143748 Nuclear VCP-like 1 224227334-224330387 Predicted intracellular proteins Evidence at protein level HPA028207, HPA028219, HPA028224, HPA028654 Supported Validated Nucleoli Renal cancer:4.10e-11 (unfavourable), Liver cancer:5.77e-5 (unfavourable), Lung cancer:2.95e-4 (favourable) Expressed in all Expressed in all skin: 18.7 NXF1 DKFZp667O0311, Mex67, TAP ENSG00000162231 Nuclear RNA export factor 1 11 62792123-62806302 Predicted intracellular proteins, Transporters Evidence at protein level CAB016327, HPA061593 Supported Supported Nucleoplasm Pancreatic cancer:4.08e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 144.9 NXT1 MTR2, P15 ENSG00000132661 Nuclear transport factor 2-like export factor 1 20 23350736-23354777 Predicted intracellular proteins Evidence at protein level HPA047471 Supported Nucleoplasm
Cytosol Renal cancer:1.15e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 26.7 OAF MGC52117 ENSG00000184232 Out at first homolog 11 120210767-120230332 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047412 Uncertain Approved Nucleus Head and neck cancer:5.71e-5 (unfavourable) Expressed in all Expressed in all liver: 80.2 OARD1 C6orf130, dJ34B21.3, MGC19570, TARG1 ENSG00000124596 O-acyl-ADP-ribose deacylase 1 6 41033627-41097787 Predicted intracellular proteins Evidence at protein level HPA029036 Approved Approved Nucleus
Nucleoli Renal cancer:1.13e-4 (favourable) Expressed in all Expressed in all testis: 109.9 OAS1 IFI-4, OIAS, OIASI ENSG00000089127 2'-5'-oligoadenylate synthetase 1, 40/46kDa 12 112906777-112933222 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003657, CAB021104 Uncertain Approved Cytosol Urothelial cancer:6.12e-6 (favourable), Pancreatic cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 91.9 OAT HOGA ENSG00000065154 Ornithine aminotransferase 10 124397303-124418976 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033576, HPA040098, HPA064742 Supported Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all small intestine: 877.2 OAZ1 AZI, MGC138338, OAZ ENSG00000104904 Ornithine decarboxylase antizyme 1 19 2269509-2273490 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA009291 Uncertain Approved Vesicles
Microtubule organizing center Pancreatic cancer:4.10e-5 (favourable), Liver cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all lymph node: 271.9 OAZ2 ENSG00000180304 Ornithine decarboxylase antizyme 2 15 64687573-64703281 Predicted intracellular proteins Evidence at protein level HPA047694 Uncertain Approved Golgi apparatus Colorectal cancer:9.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 115.7 OBFC1 bA541N10.2, FLJ22559 ENSG00000107960 Oligonucleotide/oligosaccharide-binding fold containing 1 10 103882542-103918205 Predicted intracellular proteins Evidence at protein level HPA037924, HPA037925 Supported Nucleus Renal cancer:1.12e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 48.8 OBSL1 KIAA0657 ENSG00000124006 Obscurin-like 1 2 219550729-219571859 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036404, HPA036405 Approved Approved Centrosome Glioma:8.52e-4 (unfavourable) Expressed in all Expressed in all ovary: 220.2 OCEL1 FLJ22709 ENSG00000099330 Occludin/ELL domain containing 1 19 17226204-17229219 Predicted intracellular proteins Evidence at protein level HPA042070, HPA043223 Uncertain Approved Golgi apparatus Expressed in all Expressed in all epididymis: 21.9 OCIAD1 Asrij, FLJ20455, OCIA, TPA018 ENSG00000109180 OCIA domain containing 1 4 48805212-48861817 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044803 Approved Approved Mitochondria Expressed in all Expressed in all cerebral cortex: 326.5 OCIAD2 MGC45416 ENSG00000145247 OCIA domain containing 2 4 48885019-48906937 Predicted intracellular proteins Evidence at protein level HPA040979, HPA041090 Supported Validated Mitochondria Renal cancer:2.67e-5 (favourable), Urothelial cancer:2.34e-4 (favourable), Ovarian cancer:6.56e-4 (favourable), Pancreatic cancer:6.89e-4 (unfavourable), Endometrial cancer:7.37e-4 (favourable) Expressed in all Expressed in all kidney: 150.6 OCRL OCRL1 ENSG00000122126 Oculocerebrorenal syndrome of Lowe X 129539849-129592561 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA012495 Approved Approved Microtubules
Cytosol Breast cancer:2.93e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 64.0 ODC1 ODC ENSG00000115758 Ornithine decarboxylase 1 2 10439968-10448504 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001536, CAB035996 Approved Approved Plasma membrane
Cytosol Liver cancer:3.07e-5 (unfavourable) Expressed in all Expressed in all testis: 240.7 ODF2L KIAA1229 ENSG00000122417 Outer dense fiber of sperm tails 2-like 1 86346824-86396342 Predicted intracellular proteins Evidence at protein level HPA028020, HPA028095, HPA028333 Uncertain Approved Mitochondria Renal cancer:4.69e-7 (unfavourable) Mixed Expressed in all fallopian tube: 34.0 OFD1 71-7A, CXorf5, JBTS10, RP23 ENSG00000046651 Oral-facial-digital syndrome 1 X 13734745-13769353 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031102, HPA031103, HPA031104 Approved Supported Microtubules Urothelial cancer:2.76e-7 (favourable), Renal cancer:1.63e-4 (unfavourable), Cervical cancer:9.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 34.2 OGDH E1k ENSG00000105953 Oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 7 44606572-44709066 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019514, HPA020347 Supported Validated Mitochondria Renal cancer:2.22e-14 (favourable) Expressed in all Expressed in all heart muscle: 146.5 OGFOD1 FLJ10826, KIAA1612, TPA1 ENSG00000087263 2-oxoglutarate and iron-dependent oxygenase domain containing 1 16 56451490-56479100 Predicted intracellular proteins Evidence at protein level HPA003215 Approved Approved Supported Nucleus
Cytosol Head and neck cancer:6.65e-4 (unfavourable), Liver cancer:7.02e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 21.5 OGFOD2 FLJ13491, FLJ37501 ENSG00000111325 2-oxoglutarate and iron-dependent oxygenase domain containing 2 12 122974580-122980043 Predicted intracellular proteins Evidence at protein level HPA039448, HPA040306 Approved Supported Nucleoplasm
Nuclear bodies Mixed Expressed in all testis: 23.0 OGFOD3 C17orf101, FLJ22222 ENSG00000181396 2-oxoglutarate and iron-dependent oxygenase domain containing 3 17 82389223-82418637 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052099 Uncertain Approved Nucleoplasm Renal cancer:5.72e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.3 OGFR 7-60 ENSG00000060491 Opioid growth factor receptor 20 62804835-62814000 Predicted intracellular proteins Evidence at protein level HPA017899 Supported Approved Nucleoplasm Urothelial cancer:5.19e-4 (favourable) Expressed in all Expressed in all spleen: 53.6 OGFRL1 dJ331H24.1 ENSG00000119900 Opioid growth factor receptor-like 1 6 71288803-71308950 Predicted intracellular proteins Evidence at protein level HPA027122 Approved Nucleoplasm
Golgi apparatus Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 70.6 OGG1 HMMH, HOGG1, MUTM, OGH1 ENSG00000114026 8-oxoguanine DNA glycosylase 3 9749944-9788219 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027514, CAB047301 Approved Validated Nucleoplasm Liver cancer:5.77e-5 (unfavourable), Renal cancer:2.65e-4 (favourable) Expressed in all Expressed in all lymph node: 31.0 OGT FLJ23071, HRNT1, MGC22921, O-GLCNAC ENSG00000147162 O-linked N-acetylglucosamine (GlcNAc) transferase X 71533083-71575897 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA030751, HPA030752, HPA030753, HPA030754, CAB034099 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Urothelial cancer:6.85e-7 (favourable), Renal cancer:2.36e-6 (unfavourable), Head and neck cancer:1.97e-4 (favourable), Endometrial cancer:8.33e-4 (unfavourable) Expressed in all Expressed in all spleen: 84.4 OLA1 GTPBP9, PTD004 ENSG00000138430 Obg-like ATPase 1 2 174072447-174248698 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035790, HPA041443 Approved Validated Cytosol Liver cancer:9.73e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 99.9 OMA1 FLJ33782, MPRP-1, YKR087C, ZMPOMA1 ENSG00000162600 OMA1 zinc metallopeptidase 1 58415384-58546802 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055120 Approved Approved Nucleoplasm
Mitochondria Breast cancer:1.63e-4 (favourable), Colorectal cancer:7.70e-4 (favourable), Lung cancer:8.52e-4 (favourable) Expressed in all Expressed in all prostate: 32.2 OPA1 FLJ12460, KIAA0567, MGM1, NPG, NTG ENSG00000198836 Optic atrophy 1 (autosomal dominant) 3 193593144-193697823 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA036926, HPA036927 Supported Supported Nucleoplasm
Mitochondria Pancreatic cancer:8.44e-5 (unfavourable), Renal cancer:1.84e-4 (favourable), Endometrial cancer:8.61e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 56.4 OPTN FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP ENSG00000123240 Optineurin 10 13099449-13138308 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003279, HPA003360, CAB019303 Supported Validated Cytosol Renal cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 300.2 OR2C3 OR2C4, OR2C5P, OST742 ENSG00000196242 Olfactory receptor, family 2, subfamily C, member 3 1 247530132-247533839 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA053920, HPA058578 Uncertain Supported Plasma membrane Not detected Expressed in all parathyroid gland: 26.6 ORAI1 CRACM1, FLJ14466, TMEM142A ENSG00000276045 ORAI calcium release-activated calcium modulator 1 12 121626550-121642677 Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA016583, HPA061823 Approved Supported Cytosol Ovarian cancer:4.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 48.9 ORAI3 MGC13024, TMEM142C ENSG00000175938 ORAI calcium release-activated calcium modulator 3 16 30949066-30956461 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA015022 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.87e-5 (unfavourable) Expressed in all Expressed in all prostate: 26.7 ORAOV1 TAOS1 ENSG00000149716 Oral cancer overexpressed 1 11 69653076-69675416 Predicted intracellular proteins Evidence at protein level HPA062696 Approved Nucleoplasm Renal cancer:1.51e-5 (unfavourable) Expressed in all Expressed in all epididymis: 21.5 ORC3 IMAGE50150, LATHEO, ORC3L ENSG00000135336 Origin recognition complex, subunit 3 6 87590067-87667453 Predicted intracellular proteins Evidence at protein level HPA039553, HPA053748 Supported Validated Nucleoplasm Endometrial cancer:2.89e-5 (unfavourable), Renal cancer:7.23e-4 (unfavourable) Expressed in all Expressed in all testis: 48.7 ORC4 HsORC4, ORC4L, Orc4p ENSG00000115947 Origin recognition complex, subunit 4 2 147930397-148021604 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015124, HPA064562 Approved Supported Nucleus
Nucleoli Liver cancer:4.98e-8 (unfavourable), Renal cancer:4.10e-6 (favourable), Endometrial cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all testis: 28.9 ORC5 ORC5L, Orc5p, ORC5T, PPP1R117 ENSG00000164815 Origin recognition complex, subunit 5 7 104126341-104208047 Predicted intracellular proteins Evidence at protein level HPA019730 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all testis: 34.2 ORMDL1 ENSG00000128699 ORMDL sphingolipid biosynthesis regulator 1 2 189770323-189784371 Predicted membrane proteins Evidence at protein level HPA065643 Supported Endoplasmic reticulum Renal cancer:5.84e-9 (unfavourable), Urothelial cancer:1.49e-5 (favourable), Ovarian cancer:3.04e-5 (favourable) Expressed in all Expressed in all epididymis: 153.1 ORMDL2 adoplin-2, HSPC160, MST095, MSTP095 ENSG00000123353 ORMDL sphingolipid biosynthesis regulator 2 12 55817919-55821879 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA065643 Supported Endoplasmic reticulum Endometrial cancer:3.30e-5 (favourable), Liver cancer:9.75e-4 (unfavourable) Expressed in all Expressed in all epididymis: 62.1 ORMDL3 ENSG00000172057 ORMDL sphingolipid biosynthesis regulator 3 17 39921041-39927601 Disease related genes, Predicted membrane proteins Evidence at protein level HPA065643 Supported Endoplasmic reticulum Urothelial cancer:5.18e-4 (favourable), Lung cancer:9.29e-4 (favourable) Expressed in all Expressed in all adipose tissue: 165.1 OS9 ERLEC2, OS-9 ENSG00000135506 Osteosarcoma amplified 9, endoplasmic reticulum lectin 12 57693955-57721557 Predicted secreted proteins, Transporters Evidence at protein level CAB011518, HPA013694 Supported Expressed in all Expressed in all parathyroid gland: 290.9 OSBP OSBP1 ENSG00000110048 Oxysterol binding protein 11 59574398-59616144 Predicted intracellular proteins Evidence at protein level HPA039227, HPA043625 Supported Validated Nucleus
Golgi apparatus
Cytosol Renal cancer:3.08e-7 (favourable), Colorectal cancer:2.08e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 72.8 OSBPL1A ORP-1, ORP1, OSBPL1B ENSG00000141447 Oxysterol binding protein-like 1A 18 24162044-24397880 Predicted intracellular proteins Evidence at protein level HPA040959, HPA043401 Supported Approved Nucleoplasm
Cytosol Renal cancer:4.98e-13 (favourable), Stomach cancer:1.86e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 130.4 OSBPL2 DFNA67, KIAA0772, ORP-2 ENSG00000130703 Oxysterol binding protein-like 2 20 62231922-62296213 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041127, HPA042659 Uncertain Approved Cytosol Renal cancer:4.20e-5 (favourable) Expressed in all Expressed in all skin: 49.8 OSBPL8 MST120, MSTP120, ORP8, OSBP10 ENSG00000091039 Oxysterol binding protein-like 8 12 76351797-76559809 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA001309 Uncertain Approved Vesicles
Cytosol Pancreatic cancer:9.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.6 OSBPL9 ENSG00000117859 Oxysterol binding protein-like 9 1 51577179-51798427 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027378, HPA027397 Supported Supported Golgi apparatus
Vesicles Expressed in all Expressed in all parathyroid gland: 96.5 OSCP1 C1orf102, NOR1 ENSG00000116885 Organic solute carrier partner 1 1 36415827-36450451 Predicted intracellular proteins, Transporters Evidence at protein level HPA028436, HPA052655 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Renal cancer:2.18e-6 (favourable), Endometrial cancer:6.88e-4 (favourable) Expressed in all Expressed in all testis: 126.0 OSER1 C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1 ENSG00000132823 Oxidative stress responsive serine-rich 1 20 44196496-44210791 Predicted intracellular proteins Evidence at protein level HPA045125 Approved Approved Nucleoli
Nuclear speckles Endometrial cancer:2.58e-5 (unfavourable) Expressed in all Expressed in all testis: 183.6 OSGIN2 C8orf1, hT41 ENSG00000164823 Oxidative stress induced growth inhibitor family member 2 8 89901859-89927888 Predicted intracellular proteins Evidence at transcript level HPA028515, HPA050595 Approved Approved Nucleoli Liver cancer:3.91e-6 (unfavourable), Lung cancer:2.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 88.4 OST4 ENSG00000228474 Oligosaccharyltransferase complex subunit 4 (non-catalytic) 2 27070472-27071773 Predicted membrane proteins Evidence at protein level Renal cancer:7.35e-5 (unfavourable), Liver cancer:5.11e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 341.9 OSTC DC2 ENSG00000198856 Oligosaccharyltransferase complex subunit (non-catalytic) 4 108650584-108667820 Predicted membrane proteins Evidence at protein level HPA065174 Approved Nucleoplasm Renal cancer:2.31e-8 (unfavourable), Endometrial cancer:1.44e-4 (favourable), Lung cancer:2.84e-4 (unfavourable), Head and neck cancer:6.66e-4 (unfavourable) Expressed in all Expressed in all epididymis: 211.5 OSTF1 bA235O14.1, OSF, SH3P2 ENSG00000134996 Osteoclast stimulating factor 1 9 75088543-75147265 Predicted intracellular proteins Evidence at protein level HPA020514 Approved Supported Cytosol Endometrial cancer:3.67e-5 (favourable) Expressed in all Expressed in all spleen: 124.6 OSTM1 GL, HSPC019 ENSG00000081087 Osteopetrosis associated transmembrane protein 1 6 108041409-108165854 Disease related genes, Predicted membrane proteins Evidence at protein level HPA010851 Uncertain Approved Nucleus
Vesicles
Cytosol Renal cancer:1.34e-6 (unfavourable), Stomach cancer:1.20e-4 (unfavourable), Liver cancer:4.26e-4 (unfavourable), Breast cancer:4.36e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 33.3 OTUB1 FLJ20113, FLJ40710 ENSG00000167770 OTU deubiquitinase, ubiquitin aldehyde binding 1 11 63985853-64001811 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039176, CAB072836 Approved Supported Approved Nucleus
Cytosol Head and neck cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 116.3 OTUD1 DUBA7, OTDC1 ENSG00000165312 OTU deubiquitinase 1 10 23439458-23442390 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038503, HPA038504 Uncertain Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Renal cancer:6.61e-7 (favourable), Endometrial cancer:4.59e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 43.4 OTUD4 DUBA6, HSHIN1, KIAA1046 ENSG00000164164 OTU deubiquitinase 4 4 145110838-145180161 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036623 Uncertain Approved Cytosol Expressed in all Expressed in all testis: 72.6 OTUD5 DKFZp761A052, DUBA ENSG00000068308 OTU deubiquitinase 5 X 48922028-48958386 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017375 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Lung cancer:1.48e-4 (favourable), Pancreatic cancer:8.20e-4 (favourable), Cervical cancer:9.57e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 70.1 OTULIN FAM105B, FLJ34884 ENSG00000154124 OTU deubiquitinase with linear linkage specificity 5 14664664-14699711 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051074 Uncertain Approved Plasma membrane
Mitochondria Renal cancer:2.59e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 17.2 OVCA2 ENSG00000262664 Ovarian tumor suppressor candidate 2 17 2041936-2043430 Predicted intracellular proteins Evidence at protein level HPA059002 Approved Nucleoplasm
Cytosol Not detected Expressed in all gallbladder: 34.3 OXA1L MGC133129, OXA1 ENSG00000155463 Oxidase (cytochrome c) assembly 1-like 14 22766522-22773041 Predicted membrane proteins, Transporters Evidence at protein level HPA003531 Approved Supported Mitochondria Renal cancer:4.82e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 139.8 OXR1 TLDC3 ENSG00000164830 Oxidation resistance 1 8 106270178-106752694 Predicted intracellular proteins Evidence at protein level HPA027375, HPA027380, HPA027395 Supported Supported Vesicles Renal cancer:5.82e-5 (favourable), Pancreatic cancer:3.85e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 111.1 OXSM FASN2D, FLJ20604, KS ENSG00000151093 3-oxoacyl-ACP synthase, mitochondrial 3 25782917-25794534 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021293, HPA021300, HPA021337 Supported Approved Mitochondria
Cytosol Renal cancer:4.18e-9 (favourable), Colorectal cancer:1.35e-4 (favourable), Endometrial cancer:5.51e-4 (favourable) Expressed in all Expressed in all testis: 17.3 OXSR1 KIAA1101, OSR1 ENSG00000172939 Oxidative stress responsive 1 3 38165089-38255488 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008237, CAB017181 Supported Validated Cytosol Expressed in all Expressed in all parathyroid gland: 42.3 P4HA1 C-P4Halpha(I), P4HA ENSG00000122884 Prolyl 4-hydroxylase, alpha polypeptide I 10 73007217-73096974 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA007599, HPA026593 Supported Supported Endoplasmic reticulum
Vesicles
Mitochondria Renal cancer:9.40e-9 (unfavourable), Head and neck cancer:1.19e-5 (unfavourable), Cervical cancer:3.19e-5 (unfavourable), Pancreatic cancer:2.85e-4 (unfavourable), Lung cancer:5.10e-4 (unfavourable), Breast cancer:9.01e-4 (unfavourable) Expressed in all Expressed in all placenta: 91.1 P4HA2 C-P4Halpha(II) ENSG00000072682 Prolyl 4-hydroxylase, alpha polypeptide II 5 132191838-132295315 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA016997, HPA027824, CAB062557 Supported Validated Endoplasmic reticulum
Vesicles Renal cancer:2.77e-7 (unfavourable), Cervical cancer:1.24e-5 (unfavourable), Urothelial cancer:3.12e-4 (unfavourable) Expressed in all Expressed in all epididymis: 93.7 P4HB DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB ENSG00000185624 Prolyl 4-hydroxylase, beta polypeptide 17 81843159-81860694 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB012463, HPA018884 Supported Supported Endoplasmic reticulum Renal cancer:2.30e-11 (unfavourable) Expressed in all Expressed in all small intestine: 515.3 P4HTM EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4 ENSG00000178467 Prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3 48989886-49007154 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007199 Supported Uncertain Vesicles
Cytosol Renal cancer:3.28e-5 (favourable), Endometrial cancer:8.18e-4 (favourable) Expressed in all Expressed in all fallopian tube: 49.9 PA2G4 ENSG00000170515 Proliferation-associated 2G4, 38kDa 12 56104319-56113907 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011711, CAB012428, HPA016484 Supported Approved Cytosol Renal cancer:4.59e-7 (unfavourable), Liver cancer:6.31e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 136.0 PAAF1 FLJ11848, Rpn14, WDR71 ENSG00000175575 Proteasomal ATPase-associated factor 1 11 73876699-73931124 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039952, HPA040020 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all testis: 58.0 PABPC1 PAB1, PABP1, PABPC2, PABPL1 ENSG00000070756 Poly(A) binding protein, cytoplasmic 1 8 100685816-100722809 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011536, HPA045423, HPA067156 Supported Supported Cytosol Renal cancer:5.70e-12 (unfavourable), Glioma:1.35e-4 (favourable), Liver cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all esophagus: 1155.5 PABPC4 APP-1, iPABP ENSG00000090621 Poly(A) binding protein, cytoplasmic 4 (inducible form) 1 39560816-39576790 Predicted intracellular proteins Evidence at protein level HPA027301, HPA056496 Approved Validated Cytosol Renal cancer:3.00e-10 (unfavourable), Liver cancer:1.14e-7 (unfavourable) Expressed in all Expressed in all skeletal muscle: 206.3 PABPN1 OPMD, PAB2, PABP2 ENSG00000100836 Poly(A) binding protein, nuclear 1 14 23321289-23326185 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000637 Supported Approved Renal cancer:2.41e-7 (unfavourable), Liver cancer:3.55e-4 (unfavourable), Pancreatic cancer:9.66e-4 (favourable) Expressed in all Expressed in all testis: 204.8 PACRGL C4orf28, MGC29898 ENSG00000163138 PARK2 co-regulated-like 4 20696282-20752907 Predicted intracellular proteins Evidence at protein level HPA054666 Approved Nucleoplasm
Vesicles Urothelial cancer:4.85e-4 (favourable) Expressed in all Expressed in all testis: 59.8 PACS1 FLJ10209, KIAA1175 ENSG00000175115 Phosphofurin acidic cluster sorting protein 1 11 66070363-66244747 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038914 Approved Approved Microtubules
Cytosol Expressed in all Expressed in all testis: 74.1 PACS2 KIAA0602, PACS1L ENSG00000179364 Phosphofurin acidic cluster sorting protein 2 14 105300563-105398147 Predicted intracellular proteins Evidence at protein level HPA001423, HPA077892 Approved Approved Mitochondria Liver cancer:3.11e-5 (unfavourable), Renal cancer:1.56e-4 (favourable), Pancreatic cancer:2.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 63.4 PACSIN2 SDPII ENSG00000100266 Protein kinase C and casein kinase substrate in neurons 2 22 42835412-43015145 Predicted intracellular proteins Evidence at protein level HPA049854, HPA056520 Supported Supported Nuclear speckles
Vesicles
Plasma membrane
Cytosol Renal cancer:1.09e-13 (favourable), Liver cancer:7.33e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 95.8 PAF1 F23149_1, FLJ11123, PD2 ENSG00000006712 PAF1 homolog, Paf1/RNA polymerase II complex component 19 39385852-39391195 Predicted intracellular proteins Evidence at protein level HPA041875, HPA043637 Approved Supported Nucleoplasm Pancreatic cancer:8.66e-4 (favourable), Liver cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all testis: 87.0 PAFAH1B1 LIS1, MDCR, MDS, PAFAH ENSG00000007168 Platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 17 2593210-2685615 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004489, HPA020036 Approved Validated Centrosome Renal cancer:3.16e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 179.2 PAFAH1B2 ENSG00000168092 Platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 11 117144267-117176894 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA051836 Approved Supported Nucleoli
Plasma membrane
Cytosol Pancreatic cancer:7.79e-5 (unfavourable), Lung cancer:3.07e-4 (unfavourable), Ovarian cancer:4.25e-4 (favourable), Liver cancer:9.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 68.4 PAFAH1B3 ENSG00000079462 Platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 19 42297033-42303546 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035639 Uncertain Approved Intermediate filaments Renal cancer:2.07e-4 (unfavourable), Liver cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 36.8 PAFAH2 HSD-PLA2 ENSG00000158006 Platelet-activating factor acetylhydrolase 2, 40kDa 1 25959767-25998157 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018157 Approved Renal cancer:0.00e+0 (favourable), Endometrial cancer:3.28e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 28.6 PAGR1 C16orf53, GAS, MGC4606, PA1 ENSG00000280789 PAXIP1 associated glutamate-rich protein 1 16 29815952-29820117 Predicted intracellular proteins Evidence at protein level HPA041440, HPA043608 Uncertain Expressed in all Expressed in all ovary: 60.4 PAICS ADE2H1, AIRC, PAIS ENSG00000128050 Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 4 56435741-56464579 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035895, HPA041538 Uncertain Approved Cytosol Renal cancer:5.85e-5 (unfavourable), Liver cancer:1.50e-4 (unfavourable), Thyroid cancer:2.41e-4 (unfavourable), Ovarian cancer:8.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 72.8 PAIP1 ENSG00000172239 Poly(A) binding protein interacting protein 1 5 43526267-43557758 Predicted intracellular proteins Evidence at protein level HPA076187 Approved Plasma membrane
Cytosol Pancreatic cancer:4.79e-4 (unfavourable) Expressed in all Expressed in all testis: 152.3 PAIP2 PAIP2A ENSG00000120727 Poly(A) binding protein interacting protein 2 5 139341587-139369720 Predicted intracellular proteins Evidence at protein level HPA035945, CAB037212, HPA056766 Approved Approved Vesicles Expressed in all Expressed in all testis: 305.1 PAK1 ENSG00000149269 P21 protein (Cdc42/Rac)-activated kinase 1 11 77321707-77474635 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003565, CAB005312 Supported Supported Validated Plasma membrane
Cytosol Glioma:9.48e-5 (unfavourable), Colorectal cancer:5.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 186.8 PAK1IP1 bA421M1.5, FLJ20624, hPIP1, MAK11, PIP1, WDR84 ENSG00000111845 PAK1 interacting protein 1 6 10694695-10709782 Predicted intracellular proteins Evidence at protein level HPA030112 Supported Uncertain Nucleoplasm Renal cancer:7.02e-8 (unfavourable), Liver cancer:1.35e-6 (unfavourable) Expressed in all Expressed in all prostate: 109.0 PAK2 PAK65, PAKgamma ENSG00000180370 P21 protein (Cdc42/Rac)-activated kinase 2 3 196739857-196832647 Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB007794 Approved Supported Nucleus
Vesicles Pancreatic cancer:3.36e-4 (unfavourable), Prostate cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all spleen: 61.0 PAK4 ENSG00000130669 P21 protein (Cdc42/Rac)-activated kinase 4 19 39125770-39182816 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB025747, CAB044670, HPA070175, HPA072220 Uncertain Supported Plasma membrane
Cell Junctions Renal cancer:5.29e-5 (favourable), Prostate cancer:9.85e-4 (unfavourable) Expressed in all Expressed in all prostate: 42.2 PAM PAL, PHM ENSG00000145730 Peptidylglycine alpha-amidating monooxygenase 5 102753981-103031105 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB026119, HPA042260 Supported Approved Golgi apparatus
Cytosol Endometrial cancer:1.63e-4 (favourable), Liver cancer:6.20e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 1092.7 PAM16 Magmas, Tim16, TIMM16 ENSG00000217930 Presequence translocase-associated motor 16 homolog (S. cerevisiae) 16 4331549-4355607 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA062721 Approved Nucleoplasm
Microtubules
Mitochondria Renal cancer:5.73e-5 (unfavourable), Urothelial cancer:1.33e-4 (favourable) Expressed in all Expressed in all testis: 15.2 PAN2 hPAN2, KIAA0710, USP52 ENSG00000135473 PAN2 poly(A) specific ribonuclease subunit 12 56316223-56334053 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 32.0 PAN3 ENSG00000152520 PAN3 poly(A) specific ribonuclease subunit 13 28138506-28295335 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028817 Approved Expressed in all Expressed in all spleen: 29.1 PANK2 C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN ENSG00000125779 Pantothenate kinase 2 20 3888839-3929882 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA008440 Approved Supported Cytosol Liver cancer:1.20e-5 (unfavourable) Expressed in all Expressed in all testis: 51.6 PANK3 FLJ12899 ENSG00000120137 Pantothenate kinase 3 5 168548495-168579600 Enzymes, Predicted intracellular proteins Evidence at protein level HPA062358 Approved Nucleoplasm
Golgi apparatus Colorectal cancer:3.94e-4 (favourable) Expressed in all Expressed in all duodenum: 41.9 PANX1 MRS1, PX1, UNQ2529 ENSG00000110218 Pannexin 1 11 94128928-94181972 Predicted membrane proteins, Transporters Evidence at protein level HPA016930 Uncertain Validated Plasma membrane Renal cancer:1.49e-7 (unfavourable), Lung cancer:7.09e-5 (unfavourable), Endometrial cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex,testis: 19.4 PAPD4 FLJ38499, GLD2, TUT2 ENSG00000164329 PAP associated domain containing 4 5 79612120-79686648 Enzymes, Predicted intracellular proteins Evidence at protein level HPA054468 Approved Cytosol Expressed in all Expressed in all spleen: 38.9 PAPD5 TRF4-2 ENSG00000121274 PAP associated domain containing 5 16 50152918-50235310 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042968, HPA048225 Uncertain Renal cancer:1.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.1 PAPD7 LAK-1, POLK, POLS, TRF4, TRF4-1 ENSG00000112941 PAP associated domain containing 7 5 6713007-6757048 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045487, HPA046742 Supported Supported Nucleoplasm
Nuclear membrane
Golgi apparatus Renal cancer:7.99e-5 (unfavourable), Urothelial cancer:8.55e-4 (favourable) Expressed in all Expressed in all ovary,testis: 19.0 PAPOLA PAP ENSG00000090060 Poly(A) polymerase alpha 14 96501433-96567111 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001788 Supported Validated Nucleoplasm Liver cancer:2.41e-5 (unfavourable) Expressed in all Expressed in all testis: 166.1 PAPSS1 ATPSK1, PAPSS ENSG00000138801 3'-phosphoadenosine 5'-phosphosulfate synthase 1 4 107590276-107720452 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049781 Approved Approved Nucleus
Nucleoli Liver cancer:2.70e-5 (unfavourable), Endometrial cancer:8.58e-4 (favourable), Colorectal cancer:9.14e-4 (favourable) Expressed in all Expressed in all endometrium: 73.3 PAPSS2 ATPSK2 ENSG00000198682 3'-phosphoadenosine 5'-phosphosulfate synthase 2 10 87659613-87747705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA071224 Approved Mitochondria Melanoma:1.33e-6 (unfavourable), Thyroid cancer:3.21e-5 (unfavourable), Pancreatic cancer:6.58e-4 (favourable) Expressed in all Expressed in all adrenal gland: 158.4 PARK7 DJ-1, DJ1 ENSG00000116288 Parkinson protein 7 1 7954291-7985505 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004190, CAB005870 Supported Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 505.2 PARL PRO2207, PSARL, PSARL1, RHBDS1 ENSG00000175193 Presenilin associated, rhomboid-like 3 183829385-183884933 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA019545 Approved Supported Mitochondria Urothelial cancer:9.11e-5 (favourable) Expressed in all Expressed in all epididymis: 71.5 PARN DAN ENSG00000140694 Poly(A)-specific ribonuclease 16 14435701-14632728 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006314, CAB011673, HPA012010 Supported Approved Nucleoli
Nuclear speckles Head and neck cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 27.6 PARP1 ADPRT, PARP, PPOL ENSG00000143799 Poly (ADP-ribose) polymerase 1 1 226360691-226408079 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727 Supported Validated Nucleus Renal cancer:1.35e-5 (unfavourable), Liver cancer:3.40e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 195.1 PARP10 FLJ14464 ENSG00000178685 Poly (ADP-ribose) polymerase family, member 10 8 143977153-144012772 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028122, HPA052427 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all spleen: 57.5 PARP14 KIAA1268, pART8 ENSG00000173193 Poly (ADP-ribose) polymerase family, member 14 3 122680618-122730840 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008846, HPA012063 Supported Validated Cytosol Renal cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all spleen: 51.9 PARP16 C15orf30, FLJ20509, FLJ25281, pART15 ENSG00000138617 Poly (ADP-ribose) polymerase family, member 16 15 65234460-65300618 Enzymes, Predicted membrane proteins Evidence at protein level HPA017081 Approved Expressed in all Expressed in all ovary: 13.0 PARP2 ADPRTL2 ENSG00000129484 Poly (ADP-ribose) polymerase 2 14 20343582-20357905 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA052003 Approved Approved Nucleus
Nucleoli Liver cancer:6.48e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 46.5 PARP4 ADPRTL1, p193, VAULT3, VPARP, VWA5C ENSG00000102699 Poly (ADP-ribose) polymerase family, member 4 13 24420926-24512810 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011739 Approved Supported Cytosol Renal cancer:1.21e-5 (favourable) Expressed in all Expressed in all gallbladder: 46.2 PARP6 pART17 ENSG00000137817 Poly (ADP-ribose) polymerase family, member 6 15 72241181-72272999 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026991 Approved Approved Plasma membrane Renal cancer:8.02e-8 (unfavourable), Cervical cancer:3.17e-5 (favourable), Colorectal cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all testis: 46.7 PARP8 FLJ21308, pART16 ENSG00000151883 Poly (ADP-ribose) polymerase family, member 8 5 50665899-50846522 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049183 Approved Approved Nucleoplasm
Cytosol Urothelial cancer:1.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 72.0 PARP9 BAL, BAL1 ENSG00000138496 Poly (ADP-ribose) polymerase family, member 9 3 122527924-122564577 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA066708 Supported Nucleoplasm
Mitochondria
Cytosol Ovarian cancer:6.65e-4 (favourable) Expressed in all Expressed in all spleen: 61.9 PARVB CGI-56 ENSG00000188677 Parvin, beta 22 43999211-44172949 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA062601 Approved Cytosol Expressed in all Expressed in all skeletal muscle: 68.6 PATL1 FLJ36874, Pat1b ENSG00000166889 Protein associated with topoisomerase II homolog 1 (yeast) 11 59636716-59668980 Predicted intracellular proteins Evidence at protein level HPA039030 Uncertain Supported Cytoplasmic bodies Pancreatic cancer:2.04e-4 (unfavourable), Colorectal cancer:4.56e-4 (favourable) Expressed in all Expressed in all bone marrow: 37.0 PATZ1 dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ENSG00000100105 POZ (BTB) and AT hook containing zinc finger 1 22 31325804-31346232 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047893, HPA048315 Approved Supported Nucleoplasm Renal cancer:8.54e-8 (favourable), Urothelial cancer:7.79e-6 (favourable), Glioma:6.53e-5 (favourable), Lung cancer:8.71e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 39.8 PAXBP1 C21orf66, fSAP105, GCFC, GCFC1 ENSG00000159086 PAX3 and PAX7 binding protein 1 21 32733899-32771858 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003757 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.50e-5 (unfavourable), Prostate cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 18.7 PBDC1 CXorf26, MGC874 ENSG00000102390 Polysaccharide biosynthesis domain containing 1 X 76172936-76178204 Predicted intracellular proteins Evidence at protein level HPA003155 Uncertain Approved Nucleus
Nucleoli
Cytosol Thyroid cancer:8.57e-4 (favourable) Expressed in all Expressed in all prostate: 41.0 PBLD FLJ14767, MAWBP, MAWDBP ENSG00000108187 Phenazine biosynthesis-like protein domain containing 10 68282660-68333049 Predicted intracellular proteins Evidence at protein level HPA038035, HPA038036 Supported Approved Vesicles Liver cancer:1.44e-4 (favourable) Expressed in all Expressed in all kidney: 276.9 PBRM1 BAF180, PB1 ENSG00000163939 Polybromo 1 3 52545352-52685917 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015629, HPA059373 Uncertain Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 44.5 PBX1 ENSG00000185630 Pre-B-cell leukemia homeobox 1 1 164555584-164899296 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003505, HPA003881, CAB018768 Supported Validated Nucleoplasm Mixed Expressed in all endometrium: 246.5 PBX2 G17, HOX12, PBX2MHC ENSG00000204304 Pre-B-cell leukemia homeobox 2 6 32184741-32190186 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061478 Supported Approved Nucleoplasm Endometrial cancer:8.90e-5 (unfavourable), Ovarian cancer:6.84e-4 (favourable) Expressed in all Expressed in all epididymis: 35.5 PBX3 ENSG00000167081 Pre-B-cell leukemia homeobox 3 9 125747345-125967377 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003881 Supported Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 334.1 PBXIP1 HPIP ENSG00000163346 Pre-B-cell leukemia homeobox interacting protein 1 1 154944076-154956123 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006949 Approved Approved Vesicles
Cytosol Renal cancer:9.22e-6 (favourable), Pancreatic cancer:2.64e-4 (favourable), Colorectal cancer:2.73e-4 (unfavourable), Head and neck cancer:7.19e-4 (favourable), Lung cancer:8.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 137.9 PC PCB ENSG00000173599 Pyruvate carboxylase 11 66848233-66958376 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033742, HPA043922, HPA058765 Uncertain Validated Mitochondria Ovarian cancer:7.86e-5 (unfavourable), Renal cancer:8.22e-5 (favourable) Expressed in all Expressed in all adipose tissue: 63.7 PCBD1 DCOH, PCBD, PCD ENSG00000166228 Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 10 70882280-70888784 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA037575, HPA061723 Approved Validated Nucleoplasm
Cytosol Expressed in all Expressed in all liver: 157.2 PCBD2 DCOH2, DCOHM ENSG00000132570 Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 5 134904906-135007959 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036428 Uncertain Approved Plasma membrane Expressed in all Expressed in all parathyroid gland: 16.0 PCBP1 hnRNP-E1, hnRNP-X, HNRPE1, HNRPX ENSG00000169564 Poly(rC) binding protein 1 2 70087454-70089203 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037113, HPA043803, HPA068497 Supported Validated Nuclear speckles
Cytoplasmic bodies Renal cancer:1.71e-5 (favourable) Expressed in all Expressed in all spleen: 288.8 PCBP2 hnRNP-E2, HNRNPE2, HNRPE2 ENSG00000197111 Poly(rC) binding protein 2 12 53452102-53481162 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038356 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:1.82e-5 (unfavourable), Ovarian cancer:8.23e-4 (favourable) Expressed in all Expressed in all thyroid gland: 742.9 PCBP4 LIP4, MCG10 ENSG00000090097 Poly(rC) binding protein 4 3 51957454-51974016 Predicted intracellular proteins Evidence at protein level HPA057754 Supported Cytosol Expressed in all Expressed in all cerebral cortex: 125.7 PCCA ENSG00000175198 Propionyl CoA carboxylase, alpha polypeptide 13 100089015-100530435 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041716, HPA047792 Supported Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all epididymis: 259.8 PCCB ENSG00000114054 Propionyl CoA carboxylase, beta polypeptide 3 136250306-136337896 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036939, HPA036940 Supported Renal cancer:6.47e-7 (favourable) Expressed in all Expressed in all liver: 102.6 PCED1A bA12M19.1, C20orf81, FAM113A, FLJ22376 ENSG00000132635 PC-esterase domain containing 1A 20 2835314-2841190 Predicted intracellular proteins Evidence at protein level HPA050816 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:5.96e-5 (favourable), Liver cancer:7.31e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 79.9 PCF11 KIAA0824 ENSG00000165494 PCF11 cleavage and polyadenylation factor subunit 11 83156988-83187451 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040779 Supported Nucleoplasm
Mitochondria Urothelial cancer:2.03e-5 (favourable), Head and neck cancer:1.34e-4 (favourable) Expressed in all Expressed in all testis: 44.2 PCGF3 DONG1, FLJ36550, MGC40413, RNF3, RNF3A ENSG00000185619 Polycomb group ring finger 3 4 705748-770640 Predicted intracellular proteins Evidence at protein level HPA061879 Supported Nucleoplasm Pancreatic cancer:1.44e-4 (favourable), Head and neck cancer:3.73e-4 (favourable), Urothelial cancer:5.25e-4 (favourable) Expressed in all Expressed in all skin: 79.4 PCGF5 MGC16202, RNF159 ENSG00000180628 Polycomb group ring finger 5 10 91163012-91284331 Predicted intracellular proteins Evidence at protein level HPA038349 Approved Supported Nucleoli Renal cancer:4.98e-4 (favourable), Urothelial cancer:6.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 40.3 PCGF6 MBLR, RNF134 ENSG00000156374 Polycomb group ring finger 6 10 103302796-103351134 Predicted intracellular proteins Evidence at protein level Renal cancer:4.54e-9 (unfavourable) Expressed in all Expressed in all testis: 16.2 PCID2 FLJ11305 ENSG00000126226 PCI domain containing 2 13 113177539-113208715 Predicted intracellular proteins Evidence at protein level HPA069107, HPA073074 Uncertain Approved Nucleus
Nucleoli Renal cancer:4.24e-6 (unfavourable), Head and neck cancer:7.80e-5 (unfavourable) Expressed in all Expressed in all testis: 81.5 PCIF1 bA465L10.1, C20orf67, PPP1R121 ENSG00000100982 PDX1 C-terminal inhibiting factor 1 20 45934628-45948023 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049517 Supported Supported Nucleoplasm
Microtubules
Cytokinetic bridge Renal cancer:1.50e-6 (favourable), Endometrial cancer:8.86e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 48.6 PCM1 PTC4 ENSG00000078674 Pericentriolar material 1 8 17922840-18029944 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA023370, HPA023374, CAB058695 Supported Validated Nuclear membrane
Centrosome
Cytosol Expressed in all Expressed in all testis: 275.8 PCMT1 ENSG00000120265 Protein-L-isoaspartate (D-aspartate) O-methyltransferase 6 149749443-149811420 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003239 Approved Supported Cytosol Breast cancer:4.02e-7 (unfavourable), Head and neck cancer:1.88e-4 (unfavourable), Liver cancer:2.58e-4 (unfavourable), Endometrial cancer:4.27e-4 (unfavourable), Urothelial cancer:6.38e-4 (unfavourable), Cervical cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 195.3 PCMTD1 FLJ10883 ENSG00000168300 Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 8 51817575-51899186 Predicted intracellular proteins Evidence at protein level HPA025696, HPA061444 Approved Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all parathyroid gland: 184.0 PCMTD2 C20orf36, FLJ10883 ENSG00000203880 Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 20 64255695-64287821 Predicted intracellular proteins Evidence at protein level HPA057849 Approved Approved Nucleoplasm
Mitochondria Lung cancer:2.13e-4 (favourable), Renal cancer:3.82e-4 (favourable) Expressed in all Expressed in all skin: 78.8 PCNA ENSG00000132646 Proliferating cell nuclear antigen 20 5114953-5126626 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000148, HPA030521, HPA030522, HPA030523 Supported Supported Nucleoplasm
Nuclear bodies Renal cancer:3.03e-6 (unfavourable), Cervical cancer:1.86e-5 (favourable), Liver cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 223.6 PCNP ENSG00000081154 PEST proteolytic signal containing nuclear protein 3 101574095-101594437 Predicted intracellular proteins Evidence at protein level HPA035011 Supported Supported Nucleus Liver cancer:6.00e-5 (unfavourable) Expressed in all Expressed in all endometrium: 80.2 PCNX KIAA0805, KIAA0995, PCNXL1, pecanex ENSG00000100731 Pecanex homolog (Drosophila) 14 70907405-71115382 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053532 Approved Nucleoplasm Renal cancer:4.05e-5 (favourable) Expressed in all Expressed in all testis: 38.1 PCNXL4 C14orf135 ENSG00000126773 Pecanex-like 4 (Drosophila) 14 60091911-60169133 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002076, HPA003390 Uncertain Approved Cytosol Renal cancer:6.84e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 31.6 PCSK7 LPC, PC7, PC8, SPC7 ENSG00000160613 Proprotein convertase subtilisin/kexin type 7 11 117204337-117232525 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043181, HPA052957 Uncertain Nucleus
Nuclear membrane
Nucleoli Expressed in all Expressed in all smooth muscle: 305.0 PCTP STARD2 ENSG00000141179 Phosphatidylcholine transfer protein 17 55750979-55842830 Predicted intracellular proteins Evidence at protein level HPA022979 Approved Approved Nucleus
Nucleoli Head and neck cancer:3.43e-6 (unfavourable) Expressed in all Expressed in all liver: 49.2 PCYOX1 KIAA0908, PCL1 ENSG00000116005 Prenylcysteine oxidase 1 2 70257386-70281191 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035193 Approved Renal cancer:1.89e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 138.9 PCYT1A CT, CTPCT, PCYT1 ENSG00000161217 Phosphate cytidylyltransferase 1, choline, alpha 3 196214222-196287957 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035428 Approved Approved Nucleus Liver cancer:8.65e-5 (unfavourable) Expressed in all Expressed in all duodenum: 69.0 PCYT2 ET ENSG00000185813 Phosphate cytidylyltransferase 2, ethanolamine 17 81900965-81911464 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023033, HPA023034 Supported Supported Intermediate filaments
Centrosome Renal cancer:4.29e-6 (favourable) Expressed in all Expressed in all testis: 241.0 PDAP1 HASPP28, PAP, PAP1 ENSG00000106244 PDGFA associated protein 1 7 99392048-99408829 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB021103, HPA050294, HPA060836 Approved Validated Plasma membrane
Cytosol Liver cancer:6.67e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 37.3 PDCD10 CCM3, TFAR15 ENSG00000114209 Programmed cell death 10 3 167683298-167734939 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA027095 Approved Pancreatic cancer:5.22e-5 (unfavourable), Liver cancer:2.30e-4 (unfavourable), Head and neck cancer:3.89e-4 (unfavourable), Renal cancer:5.88e-4 (favourable), Endometrial cancer:9.34e-4 (unfavourable) Expressed in all Expressed in all testis: 80.5 PDCD11 ALG-4, KIAA0185, RRP5 ENSG00000148843 Programmed cell death 11 10 103396648-103446292 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017924, CAB026472 Approved Supported Nucleoli
Vesicles Liver cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all testis: 27.9 PDCD2 RP8, ZMYND7 ENSG00000071994 Programmed cell death 2 6 170575295-170584692 Predicted intracellular proteins Evidence at protein level HPA026713, HPA075534 Uncertain Approved Nucleoplasm
Cytokinetic bridge Liver cancer:1.42e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 59.8 PDCD4 H731 ENSG00000150593 Programmed cell death 4 (neoplastic transformation inhibitor) 10 110871795-110900006 Predicted intracellular proteins Evidence at protein level HPA001032, HPA027214, CAB037024 Supported Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 458.8 PDCD5 MGC9294, TFAR19 ENSG00000105185 Programmed cell death 5 19 32581068-32587452 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018471 Supported Approved Nucleus
Cytosol Renal cancer:0.00e+0 (unfavourable), Endometrial cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all testis: 174.5 PDCD6 ALG-2, PEF1B ENSG00000249915 Programmed cell death 6 5 271621-353856 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA047221 Approved Cytosol Renal cancer:5.16e-6 (unfavourable), Liver cancer:5.47e-5 (unfavourable), Urothelial cancer:2.19e-4 (favourable) Expressed in all Expressed in all epididymis: 120.0 PDCD6IP AIP1, Alix, Hp95 ENSG00000170248 Programmed cell death 6 interacting protein 3 33798352-33869707 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA011905, CAB016212 Approved Validated Cytosol Renal cancer:3.90e-9 (favourable), Colorectal cancer:1.16e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 63.2 PDCD7 ES18, HES18 ENSG00000090470 Programmed cell death 7 15 65117379-65133836 Predicted intracellular proteins Evidence at protein level HPA049388 Approved Approved Nucleoli
Plasma membrane Renal cancer:1.00e-4 (unfavourable) Expressed in all Expressed in all testis: 30.7 PDCL DKFZp564M1863, PhLP ENSG00000136940 Phosducin-like 9 122798389-122828631 Predicted intracellular proteins Evidence at protein level HPA021571, HPA021647, CAB026473 Uncertain Supported Cytosol Renal cancer:7.00e-4 (favourable) Expressed in all Expressed in all endometrium: 23.8 PDCL3 VIAF1 ENSG00000115539 Phosducin-like 3 2 100562690-100576735 Predicted intracellular proteins Evidence at protein level HPA018469, HPA027094 Approved Validated Nucleus
Cytosol Renal cancer:2.55e-5 (unfavourable), Liver cancer:6.07e-5 (unfavourable), Urothelial cancer:4.23e-4 (favourable) Expressed in all Expressed in all smooth muscle: 39.8 PDDC1 FLJ34283 ENSG00000177225 Parkinson disease 7 domain containing 1 11 767220-777488 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008812 Uncertain Supported Nucleoplasm Renal cancer:3.79e-5 (favourable), Liver cancer:3.98e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 31.8 PDE12 2'-PDE, DKFZp667B1218 ENSG00000174840 Phosphodiesterase 12 3 57556276-57566844 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043171 Approved Renal cancer:3.63e-8 (favourable), Colorectal cancer:2.85e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 15.7 PDE4DIP CMYA2, KIAA0454, KIAA0477, MMGL ENSG00000178104 Phosphodiesterase 4D interacting protein 1 148808181-149048286 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA008162, HPA012678 Uncertain Supported Golgi apparatus Expressed in all Expressed in all skeletal muscle: 769.6 PDE5A ENSG00000138735 Phosphodiesterase 5A, cGMP-specific 4 119494395-119628991 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA004729, HPA012873 Approved Approved Cytosol Urothelial cancer:1.17e-4 (unfavourable), Cervical cancer:5.20e-4 (favourable) Expressed in all Expressed in all prostate: 90.8 PDE6D JBTS22 ENSG00000156973 Phosphodiesterase 6D, cGMP-specific, rod, delta 2 231732425-231786272 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037433, HPA037434 Uncertain Renal cancer:4.02e-5 (unfavourable), Urothelial cancer:4.97e-4 (favourable) Expressed in all Expressed in all testis: 48.0 PDE7A HCP1 ENSG00000205268 Phosphodiesterase 7A 8 65717510-65842322 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB018770, HPA027340 Approved Renal cancer:1.35e-4 (unfavourable), Liver cancer:5.64e-4 (unfavourable) Expressed in all Expressed in all lymph node: 69.7 PDE8A HsT19550 ENSG00000073417 Phosphodiesterase 8A 15 84980440-85139145 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA007722 Approved Approved Golgi apparatus Expressed in all Expressed in all parathyroid gland: 29.6 PDF ENSG00000258429 Peptide deformylase (mitochondrial) 16 69328621-69330595 Enzymes, Predicted secreted proteins Evidence at protein level HPA063409 Approved Approved Nucleoplasm
Mitochondria Head and neck cancer:2.73e-4 (unfavourable), Cervical cancer:4.63e-4 (unfavourable), Renal cancer:6.11e-4 (favourable), Lung cancer:7.35e-4 (unfavourable) Expressed in all Expressed in all kidney: 7.8 PDGFA PDGF-A, PDGF1 ENSG00000197461 Platelet-derived growth factor alpha polypeptide 7 497258-520296 Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB005579 Uncertain Approved Vesicles
Microtubule organizing center Glioma:1.51e-4 (unfavourable), Head and neck cancer:1.78e-4 (unfavourable), Urothelial cancer:8.67e-4 (unfavourable) Expressed in all Expressed in all placenta: 39.1 PDGFRA CD140a, GAS9, PDGFR2 ENSG00000134853 Platelet-derived growth factor receptor, alpha polypeptide 4 54229097-54298247 Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA004947, CAB018143 Supported Supported Nucleus
Plasma membrane
Cell Junctions Renal cancer:9.79e-6 (unfavourable), Head and neck cancer:9.33e-4 (favourable) Expressed in all Expressed in all ovary: 222.0 PDHA1 PDHA ENSG00000131828 Pyruvate dehydrogenase (lipoamide) alpha 1 X 19343893-19361705 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA047487, HPA047864, HPA063053 Approved Supported Mitochondria Renal cancer:1.13e-7 (favourable) Expressed in all Expressed in all heart muscle: 231.0 PDHB ENSG00000168291 Pyruvate dehydrogenase (lipoamide) beta 3 58427630-58433857 Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033794, HPA036744, HPA036745 Supported Supported Nucleoplasm
Mitochondria Renal cancer:2.79e-8 (favourable) Expressed in all Expressed in all heart muscle: 111.5 PDHX DLDBP, E3BP, OPDX, PDX1, proX ENSG00000110435 Pyruvate dehydrogenase complex, component X 11 34915829-35020591 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038484, HPA038485 Supported Approved Nucleus
Plasma membrane
Mitochondria Renal cancer:1.83e-5 (favourable) Expressed in all Expressed in all testis: 51.8 PDIA3 ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC ENSG00000167004 Protein disulfide isomerase family A, member 3 15 43746392-43773279 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA002645, HPA003230, CAB011199, CAB015181 Supported Validated Endoplasmic reticulum Renal cancer:2.11e-8 (unfavourable), Head and neck cancer:8.95e-5 (unfavourable), Endometrial cancer:2.05e-4 (favourable) Expressed in all Expressed in all thyroid gland: 91.1 PDIA4 ERP70, ERP72 ENSG00000155660 Protein disulfide isomerase family A, member 4 7 149003062-149028641 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA006139, HPA006140, CAB017368 Supported Supported Endoplasmic reticulum Renal cancer:5.20e-9 (unfavourable), Glioma:8.61e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 371.2 PDIA6 ERp5, P5, TXNDC7 ENSG00000143870 Protein disulfide isomerase family A, member 6 2 10783391-10837977 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB034347, HPA034652, HPA034653 Supported Supported Endoplasmic reticulum
Cytosol Renal cancer:2.51e-6 (unfavourable), Liver cancer:3.63e-5 (unfavourable), Head and neck cancer:1.20e-4 (unfavourable), Cervical cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 589.5 PDIK1L CLIK1L ENSG00000175087 PDLIM1 interacting kinase 1 like 1 26111165-26125543 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA064157 Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 27.3 PDK1 ENSG00000152256 Pyruvate dehydrogenase kinase, isozyme 1 2 172555373-172608669 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017554, HPA027376, HPA059083 Approved Approved Nucleoli
Mitochondria Renal cancer:1.10e-8 (unfavourable), Cervical cancer:7.30e-5 (unfavourable) Expressed in all Expressed in all testis: 22.3 PDK2 PDHK2 ENSG00000005882 Pyruvate dehydrogenase kinase, isozyme 2 17 50094737-50112152 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008287 Supported Supported Nucleoplasm
Mitochondria Renal cancer:9.59e-5 (favourable), Cervical cancer:5.87e-4 (favourable) Expressed in all Expressed in all epididymis: 149.0 PDK4 ENSG00000004799 Pyruvate dehydrogenase kinase, isozyme 4 7 95583499-95596491 Enzymes, Predicted intracellular proteins Evidence at protein level HPA056731 Approved Stomach cancer:1.80e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 756.5 PDLIM1 CLIM1, CLP-36, CLP36, hCLIM1 ENSG00000107438 PDZ and LIM domain 1 10 95237572-95291024 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017010, CAB072838, CAB072840 Approved Supported Plasma membrane
Cell Junctions
Actin filaments Endometrial cancer:1.14e-5 (favourable) Expressed in all Expressed in all small intestine: 278.6 PDLIM2 ENSG00000120913 PDZ and LIM domain 2 (mystique) 8 22578279-22598025 Predicted intracellular proteins Evidence at protein level HPA003880 Approved Approved Actin filaments
Focal adhesion sites Renal cancer:1.37e-7 (unfavourable), Glioma:7.23e-4 (unfavourable) Expressed in all Expressed in all spleen: 273.0 PDLIM5 Enh, LIM ENSG00000163110 PDZ and LIM domain 5 4 94451857-94668227 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013511, HPA016740, HPA020026 Approved Supported Nucleoplasm
Plasma membrane
Focal adhesion sites Tissue enriched Expressed in all skeletal muscle: 407.0 PDLIM7 ENIGMA ENSG00000196923 PDZ and LIM domain 7 (enigma) 5 177483394-177497606 Predicted intracellular proteins Evidence at protein level HPA018794, HPA048815 Approved Validated Actin filaments
Focal adhesion sites Renal cancer:6.19e-10 (unfavourable), Lung cancer:4.07e-4 (unfavourable), Endometrial cancer:5.45e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 285.6 PDP1 PDH, PDP, PPM2C ENSG00000164951 Pyruvate dehyrogenase phosphatase catalytic subunit 1 8 93857807-93926066 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA018483, HPA019081, HPA021152 Uncertain Supported Nucleoplasm
Mitochondria
Cytosol Renal cancer:8.42e-9 (favourable), Breast cancer:8.61e-5 (unfavourable), Ovarian cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 82.7 PDPK1 PDK1 ENSG00000140992 3-phosphoinositide dependent protein kinase 1 16 2537964-2603188 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004272, HPA035199, HPA068961 Supported Approved Vesicles Renal cancer:1.29e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 51.3 PDPR PDP3 ENSG00000090857 Pyruvate dehydrogenase phosphatase regulatory subunit 16 70113626-70162537 Predicted intracellular proteins Evidence at protein level HPA048092, HPA070386 Uncertain Approved Mitochondria Renal cancer:8.36e-4 (favourable) Expressed in all Expressed in all testis: 29.0 PDRG1 C20orf126, dJ310O13.3 ENSG00000088356 P53 and DNA-damage regulated 1 20 31944342-31952092 Predicted intracellular proteins Evidence at protein level HPA047084, HPA063542 Approved Approved Actin filaments Liver cancer:2.62e-5 (unfavourable), Endometrial cancer:1.69e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 63.6 PDS5A KIAA0648, PIG54, SCC-112 ENSG00000121892 PDS5 cohesin associated factor A 4 39822863-39977956 Predicted intracellular proteins Evidence at protein level HPA036661, HPA036662 Supported Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 56.3 PDS5B APRIN, AS3, CG008, FLJ23236, KIAA0979 ENSG00000083642 PDS5 cohesin associated factor B 13 32586427-32778019 Predicted intracellular proteins Evidence at protein level HPA039513, HPA040015 Supported Validated Nucleoplasm Expressed in all Expressed in all endometrium: 31.1 PDSS2 bA59I9.3, C6orf210 ENSG00000164494 Prenyl (decaprenyl) diphosphate synthase, subunit 2 6 107152557-107459564 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029685, HPA029686 Approved Validated Cytosol Renal cancer:3.75e-7 (favourable), Breast cancer:1.34e-5 (unfavourable), Colorectal cancer:5.74e-5 (favourable) Expressed in all Expressed in all prostate: 23.6 PDXDC1 KIAA0251 ENSG00000179889 Pyridoxal-dependent decarboxylase domain containing 1 16 14974591-15139339 Predicted intracellular proteins Evidence at protein level HPA047369, HPA049121, HPA051484 Approved Validated Golgi apparatus
Vesicles Renal cancer:3.13e-4 (favourable) Expressed in all Expressed in all testis: 105.9 PDXK C21orf124, C21orf97, FLJ21324, FLJ31940, MGC15873, PKH, PNK, PRED79 ENSG00000160209 Pyridoxal (pyridoxine, vitamin B6) kinase 21 43719094-43762307 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030196, HPA030197, HPA030198, CAB033918 Approved Validated Nucleus Expressed in all Expressed in all cerebral cortex: 47.6 PDZD11 PDZK11 ENSG00000120509 PDZ domain containing 11 X 70286595-70290514 Predicted intracellular proteins Evidence at protein level HPA003972 Approved Expressed in all Expressed in all cerebral cortex: 60.1 PDZD8 bA129M16.2, FLJ34427, PDZK8 ENSG00000165650 PDZ domain containing 8 10 117277274-117375467 Predicted secreted proteins Evidence at protein level HPA015716, HPA051610 Uncertain Approved Nucleoli fibrillar center
Plasma membrane Pancreatic cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 46.6 PEA15 HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED ENSG00000162734 Phosphoprotein enriched in astrocytes 15 1 160205337-160215376 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028356 Approved Nucleus
Cytosol Renal cancer:6.53e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1090.0 PEBP1 HCNP, PBP, PEBP, RKIP ENSG00000089220 Phosphatidylethanolamine binding protein 1 12 118135858-118145584 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008819, CAB009906, CAB013493 Supported Approved Plasma membrane
Cytosol Renal cancer:2.15e-13 (favourable), Pancreatic cancer:1.52e-4 (favourable) Expressed in all Expressed in all adrenal gland: 1649.3 PECAM1 CD31 ENSG00000261371 Platelet/endothelial cell adhesion molecule 1 17 64319415-64413776 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004690 Supported Renal cancer:8.98e-5 (unfavourable) Expressed in all Expressed in all placenta: 654.4 PECR HSA250303, SDR29C1, TERP ENSG00000115425 Peroxisomal trans-2-enoyl-CoA reductase 2 215996329-216082955 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021593, HPA022539 Approved Supported Peroxisomes Renal cancer:1.36e-5 (favourable) Expressed in all Expressed in all liver: 82.9 PEF1 PEF1A ENSG00000162517 Penta-EF-hand domain containing 1 1 31629862-31644896 Predicted intracellular proteins Evidence at protein level HPA061608 Approved Nucleoplasm
Vesicles
Cytosol Liver cancer:2.88e-4 (unfavourable), Cervical cancer:3.95e-4 (favourable) Expressed in all Expressed in all thyroid gland: 182.4 PELI1 ENSG00000197329 Pellino E3 ubiquitin protein ligase 1 2 64092652-64144454 Predicted intracellular proteins Evidence at protein level HPA053182 Uncertain Approved Nucleus
Nucleoli
Intermediate filaments Renal cancer:5.67e-6 (unfavourable), Endometrial cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 144.1 PELO ENSG00000152684 Pelota homolog (Drosophila) 5 52787940-52804046 Predicted intracellular proteins Evidence at protein level HPA031458 Approved Approved Nucleoli fibrillar center Breast cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 20.1 PELP1 MNAR ENSG00000141456 Proline, glutamate and leucine rich protein 1 17 4669774-4704337 Predicted intracellular proteins Evidence at protein level HPA053966, HPA056028, HPA060760 Supported Validated Nucleus
Nucleoli Pancreatic cancer:4.07e-5 (favourable), Liver cancer:6.44e-4 (unfavourable) Expressed in all Expressed in all testis: 35.4 PEMT PEMPT, PEMT2 ENSG00000133027 Phosphatidylethanolamine N-methyltransferase 17 17505563-17591708 Enzymes, Predicted membrane proteins Evidence at protein level HPA042375 Approved Approved Cytosol Endometrial cancer:6.77e-6 (favourable) Expressed in all Expressed in all epididymis: 205.4 PEPD ENSG00000124299 Peptidase D 19 33386950-33521794 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015599 Approved Approved Nucleoplasm Renal cancer:6.50e-9 (favourable) Expressed in all Expressed in all kidney: 341.0 PER1 PER, RIGUI ENSG00000179094 Period circadian clock 1 17 8140472-8156506 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA047947, HPA067064 Supported Nucleoplasm
Cytosol Stomach cancer:1.94e-4 (unfavourable), Liver cancer:2.56e-4 (favourable), Cervical cancer:3.89e-4 (favourable) Expressed in all Expressed in all thyroid gland: 70.1 PER2 KIAA0347 ENSG00000132326 Period circadian clock 2 2 238244038-238290102 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA060510 Supported Head and neck cancer:2.29e-4 (favourable) Expressed in all Expressed in all testis: 22.5 PES1 PES ENSG00000100029 Pescadillo ribosomal biogenesis factor 1 22 30576625-30607083 Predicted intracellular proteins Evidence at protein level HPA040210, HPA062439, HPA066670 Supported Validated Nucleus
Nucleoli Liver cancer:1.84e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 49.4 PET100 C19orf79 ENSG00000229833 PET100 homolog 19 7629737-7631956 Predicted intracellular proteins Evidence at protein level Urothelial cancer:2.44e-4 (favourable), Cervical cancer:6.81e-4 (favourable), Lung cancer:7.97e-4 (favourable) Expressed in all Expressed in all adrenal gland: 54.9 PET117 ENSG00000232838 PET117 homolog 20 18137873-18143169 Predicted secreted proteins Evidence at protein level HPA047716 Approved Liver cancer:4.76e-6 (unfavourable), Renal cancer:4.15e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 24.1 PEX1 ZWS, ZWS1 ENSG00000127980 Peroxisomal biogenesis factor 1 7 92487020-92528531 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA020235 Approved Supported Peroxisomes Expressed in all Expressed in all parathyroid gland: 22.2 PEX10 RNF69 ENSG00000157911 Peroxisomal biogenesis factor 10 1 2403964-2413797 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA049458, HPA049755 Approved Approved Nucleoplasm Renal cancer:4.16e-6 (favourable), Breast cancer:4.50e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 19.3 PEX11B ENSG00000131779 Peroxisomal biogenesis factor 11 beta 1 145911350-145918837 Disease related genes, Predicted membrane proteins Evidence at protein level HPA050104 Supported Liver cancer:2.67e-4 (unfavourable), Lung cancer:6.85e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 44.9 PEX13 ENSG00000162928 Peroxisomal biogenesis factor 13 2 61017225-61051990 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA032141, HPA032142, CAB032689 Supported Supported Vesicles Pancreatic cancer:8.07e-5 (unfavourable) Expressed in all Expressed in all testis: 27.4 PEX14 ENSG00000142655 Peroxisomal biogenesis factor 14 1 10472288-10630758 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA046104, HPA049231 Supported Supported Nucleoli fibrillar center
Peroxisomes Expressed in all Expressed in all seminal vesicle: 32.3 PEX16 ENSG00000121680 Peroxisomal biogenesis factor 16 11 45909669-45918812 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043286 Approved Urothelial cancer:9.06e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 27.5 PEX19 D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1 ENSG00000162735 Peroxisomal biogenesis factor 19 1 160276812-160286348 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA044837, HPA051966 Supported Validated Peroxisomes Renal cancer:2.92e-5 (favourable) Expressed in all Expressed in all adipose tissue: 85.8 PEX2 PAF-1, PMP35, PXMP3, RNF72, ZWS3 ENSG00000164751 Peroxisomal biogenesis factor 2 8 76980258-77001044 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA010983, HPA011410, HPA027729 Approved Supported Vesicles Expressed in all Expressed in all seminal vesicle: 111.4 PEX26 FLJ20695 ENSG00000215193 Peroxisomal biogenesis factor 26 22 18077920-18131138 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB070429 Approved Renal cancer:1.38e-4 (favourable), Liver cancer:3.10e-4 (unfavourable), Colorectal cancer:9.92e-4 (favourable) Expressed in all Expressed in all small intestine: 34.8 PEX3 ENSG00000034693 Peroxisomal biogenesis factor 3 6 143450807-143490010 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042830, HPA058006 Supported Supported Nucleoplasm
Peroxisomes Renal cancer:3.80e-4 (favourable) Expressed in all Expressed in all adrenal gland: 54.6 PEX5 PTS1R, PXR1 ENSG00000139197 Peroxisomal biogenesis factor 5 12 7188685-7218574 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039259, HPA039260 Supported Supported Golgi apparatus
Cytosol Expressed in all Expressed in all testis: 86.3 PEX6 PAF-2, PXAAA1 ENSG00000124587 Peroxisomal biogenesis factor 6 6 42963870-42979220 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA025924, HPA074179 Supported Approved Nucleoplasm
Vesicles Expressed in all Expressed in all fallopian tube: 36.4 PEX7 PTS2R, RD ENSG00000112357 Peroxisomal biogenesis factor 7 6 136822564-136913937 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA049202 Uncertain Renal cancer:1.85e-10 (favourable), Colorectal cancer:1.61e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.8 PFAS FGARAT, KIAA0361, PURL ENSG00000178921 Phosphoribosylformylglycinamidine synthase 17 8247618-8270491 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA022140, HPA022886 Supported Approved Nucleoplasm
Plasma membrane Liver cancer:9.19e-4 (unfavourable) Expressed in all Expressed in all lymph node: 11.8 PFDN1 PFD1 ENSG00000113068 Prefoldin subunit 1 5 140245039-140303121 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006499 Approved Approved Nucleoli
Plasma membrane
Cytosol Liver cancer:8.81e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 106.6 PFDN2 ENSG00000143256 Prefoldin subunit 2 1 161100556-161118111 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028700, HPA058304 Approved Validated Cytosol Renal cancer:4.39e-8 (unfavourable), Head and neck cancer:9.10e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 109.9 PFDN5 MM-1, PFD5 ENSG00000123349 Prefoldin subunit 5 12 53295291-53299450 Predicted intracellular proteins Evidence at protein level HPA008587 Approved Renal cancer:1.54e-6 (unfavourable), Pancreatic cancer:5.45e-4 (favourable) Expressed in all Expressed in all epididymis: 1060.5 PFDN6 H2-KE2, HKE2, KE-2, PFD6 ENSG00000204220 Prefoldin subunit 6 6 33289302-33298401 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043032, HPA048123 Supported Approved Nucleus
Golgi apparatus Ovarian cancer:1.01e-4 (favourable), Renal cancer:8.97e-4 (unfavourable) Expressed in all Expressed in all testis: 20.9 PFKFB2 ENSG00000123836 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1 207034366-207081024 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049975, HPA063575 Uncertain Validated Nucleus Renal cancer:3.23e-7 (favourable), Thyroid cancer:8.63e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 85.9 PFKFB3 ENSG00000170525 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 10 6144934-6235545 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008266, CAB020795, HPA043889 Uncertain Validated Nucleoplasm Renal cancer:1.87e-7 (unfavourable) Expressed in all Expressed in all adipose tissue: 343.9 PFKL ENSG00000141959 Phosphofructokinase, liver 21 44300051-44327376 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030047 Approved Approved Nucleoli
Mitochondria Ovarian cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all small intestine: 103.8 PFKM PFK-1, PFKX, PPP1R122 ENSG00000152556 Phosphofructokinase, muscle 12 48105139-48146404 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA002117 Approved Approved Endoplasmic reticulum Renal cancer:2.28e-7 (favourable), Endometrial cancer:5.85e-6 (unfavourable), Head and neck cancer:7.91e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 549.4 PFKP PFK-C, PFKF ENSG00000067057 Phosphofructokinase, platelet 10 3066333-3137712 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018257, HPA056484 Uncertain Supported Cytosol Liver cancer:8.72e-6 (unfavourable), Head and neck cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all testis: 286.0 PFN1 ENSG00000108518 Profilin 1 17 4945652-4949061 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB037134, CAB037140 Supported Supported Cytosol Renal cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all appendix: 919.1 PFN2 ENSG00000070087 Profilin 2 3 149964904-150050788 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035611, CAB037073 Supported Liver cancer:2.19e-7 (unfavourable), Endometrial cancer:2.93e-4 (unfavourable), Head and neck cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 420.7 PGAM1 PGAM-B, PGAMA ENSG00000171314 Phosphoglycerate mutase 1 (brain) 10 97426160-97433441 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042528, HPA049237, HPA060483 Approved Approved Nucleoplasm Breast cancer:2.04e-4 (unfavourable), Cervical cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 422.5 PGAM5 BXLBv68, MGC5352 ENSG00000247077 PGAM family member 5, serine/threonine protein phosphatase, mitochondrial 12 132710819-132722734 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036978, HPA036979, CAB068215 Supported Supported Mitochondria Liver cancer:1.13e-6 (unfavourable) Expressed in all Expressed in all testis: 28.3 PGAP2 CWH43-N, FRAG1, MRT21 ENSG00000148985 Post-GPI attachment to proteins 2 11 3797724-3826371 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA063099 Approved Approved Microtubules Liver cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all epididymis: 258.9 PGAP3 CAB2, MGC9753, PER1, PERLD1, PP1498 ENSG00000161395 Post-GPI attachment to proteins 3 17 39671122-39696797 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA016591 Approved Approved Plasma membrane
Cytosol Renal cancer:3.89e-4 (favourable), Liver cancer:3.94e-4 (favourable), Ovarian cancer:6.82e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 35.5 PGD ENSG00000142657 Phosphogluconate dehydrogenase 1 10398592-10420144 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031314, HPA031315 Approved Supported Approved Intermediate filaments
Cytosol Liver cancer:3.98e-4 (unfavourable) Expressed in all Expressed in all esophagus: 488.7 PGGT1B BGGI, GGTI ENSG00000164219 Protein geranylgeranyltransferase type I, beta subunit 5 115204012-115262872 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030646 Uncertain Approved Nucleoplasm
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all parathyroid gland: 18.6 PGK1 ENSG00000102144 Phosphoglycerate kinase 1 X 78065188-78129296 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB010065, HPA045385 Approved Breast cancer:7.05e-8 (unfavourable), Head and neck cancer:2.65e-6 (unfavourable), Cervical cancer:2.69e-5 (unfavourable), Liver cancer:2.74e-4 (unfavourable), Pancreatic cancer:8.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 116.6 PGLS 6PGL ENSG00000130313 6-phosphogluconolactonase 19 17511629-17521288 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040744, HPA042032 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all fallopian tube: 46.2 PGM1 ENSG00000079739 Phosphoglucomutase 1 1 63593276-63660245 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004666, HPA024190, HPA024637, HPA046329 Approved Validated Actin filaments Pancreatic cancer:8.74e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 513.0 PGM3 AGM1, DKFZP434B187, PAGM ENSG00000013375 Phosphoglucomutase 3 6 83161150-83193936 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004998, HPA029759, HPA029760 Supported Approved Nucleoplasm
Cytosol Renal cancer:2.39e-7 (unfavourable), Cervical cancer:5.67e-4 (unfavourable), Breast cancer:8.78e-4 (unfavourable), Ovarian cancer:9.96e-4 (favourable) Expressed in all Expressed in all prostate: 78.7 PGP ENSG00000184207 Phosphoglycolate phosphatase 16 2211997-2214807 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043096, HPA046739 Approved Approved Nuclear bodies Urothelial cancer:6.42e-4 (favourable), Renal cancer:7.05e-4 (favourable) Expressed in all Expressed in all testis: 28.2 PGPEP1 Pcp, PGP, PGP-I, PGPI ENSG00000130517 Pyroglutamyl-peptidase I 19 18340587-18369950 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035368, HPA055277 Approved Approved Golgi apparatus Renal cancer:3.71e-8 (favourable), Pancreatic cancer:1.71e-4 (favourable), Melanoma:6.80e-4 (favourable) Expressed in all Expressed in all kidney: 29.2 PGRMC1 HPR6.6 ENSG00000101856 Progesterone receptor membrane component 1 X 119236245-119244466 Predicted membrane proteins Evidence at protein level HPA002877 Supported Approved Nucleoli
Endoplasmic reticulum Head and neck cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all liver: 339.5 PGRMC2 DG6, PMBP ENSG00000164040 Progesterone receptor membrane component 2 4 128269237-128288829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041172, HPA058652 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Endometrial cancer:3.62e-4 (favourable), Renal cancer:9.60e-4 (favourable) Expressed in all Expressed in all small intestine: 136.2 PGS1 DKFZP762M186 ENSG00000087157 Phosphatidylglycerophosphate synthase 1 17 78378640-78425114 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022526 Approved Approved Vesicles
Cell Junctions
Intermediate filaments Renal cancer:1.16e-5 (unfavourable), Pancreatic cancer:7.33e-5 (favourable), Liver cancer:1.37e-4 (unfavourable), Prostate cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 26.5 PHACTR2 C6orf56, KIAA0680 ENSG00000112419 Phosphatase and actin regulator 2 6 143536845-143831185 Predicted intracellular proteins Evidence at protein level HPA031719, HPA031720, HPA031725 Approved Renal cancer:1.99e-4 (favourable) Expressed in all Expressed in all placenta: 119.1 PHACTR4 FLJ13171, PPP1R124 ENSG00000204138 Phosphatase and actin regulator 4 1 28369582-28500369 Predicted intracellular proteins Evidence at protein level HPA028985 Approved Approved Plasma membrane
Intermediate filaments
Cytosol Head and neck cancer:1.05e-4 (favourable) Expressed in all Expressed in all esophagus: 35.9 PHAX FLJ13193, RNUXA ENSG00000164902 Phosphorylated adaptor for RNA export 5 126600268-126627252 Predicted intracellular proteins, Transporters Evidence at protein level HPA059630, HPA070326 Supported Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 17.9 PHB PHB1 ENSG00000167085 Prohibitin 17 49404049-49414905 Plasma proteins, Predicted secreted proteins Evidence at protein level HPA003280 Supported Supported Vesicles
Mitochondria Head and neck cancer:1.58e-4 (unfavourable), Renal cancer:3.77e-4 (favourable), Liver cancer:9.91e-4 (unfavourable) Expressed in all Expressed in all kidney: 201.1 PHB2 Bap37, BCAP37, p22, REA ENSG00000215021 Prohibitin 2 12 6965327-6970825 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB014889, CAB026335, HPA039874 Supported Validated Mitochondria Endometrial cancer:3.80e-4 (unfavourable) Expressed in all Expressed in all ovary: 268.5 PHC1 EDR1, HPH1, RAE28 ENSG00000111752 Polyhomeotic homolog 1 (Drosophila) 12 8913896-8941467 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA006973 Approved Supported Nucleus Tissue enriched Expressed in all testis: 80.4 PHC2 EDR2, HPH2 ENSG00000134686 Polyhomeotic homolog 2 (Drosophila) 1 33323623-33431052 Predicted intracellular proteins Evidence at protein level HPA047403 Supported Supported Nucleoplasm Liver cancer:2.28e-6 (unfavourable), Renal cancer:2.35e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 86.6 PHC3 EDR3, FLJ12729, FLJ12967, HPH3 ENSG00000173889 Polyhomeotic homolog 3 (Drosophila) 3 170086732-170181749 Predicted intracellular proteins Evidence at protein level HPA039162, HPA062031 Approved Supported Nucleus Expressed in all Expressed in all parathyroid gland: 66.3 PHF10 BAF45a, FLJ10975, XAP135 ENSG00000130024 PHD finger protein 10 6 169703905-169725566 Predicted intracellular proteins Evidence at protein level HPA055649 Supported Supported Nucleus Pancreatic cancer:1.12e-5 (favourable), Renal cancer:1.56e-5 (unfavourable), Liver cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 106.6 PHF11 BCAP, IGER, NY-REN-34 ENSG00000136147 PHD finger protein 11 13 49495610-49528987 Predicted intracellular proteins Evidence at protein level HPA016566, HPA016708 Uncertain Supported Nucleoplasm
Nuclear membrane Renal cancer:4.46e-7 (unfavourable), Endometrial cancer:7.98e-6 (favourable), Urothelial cancer:3.46e-4 (favourable) Expressed in all Expressed in all thyroid gland: 57.4 PHF12 KIAA1523, PF1 ENSG00000109118 PHD finger protein 12 17 28905250-28951771 Predicted intracellular proteins Evidence at protein level HPA021410, HPA021452 Approved Validated Nucleoplasm Renal cancer:1.24e-5 (unfavourable) Expressed in all Expressed in all prostate: 26.7 PHF13 MGC43399 ENSG00000116273 PHD finger protein 13 1 6613685-6624033 Predicted intracellular proteins Evidence at protein level HPA026830 Uncertain Liver cancer:6.86e-4 (unfavourable) Expressed in all Expressed in all testis: 58.8 PHF14 KIAA0783 ENSG00000106443 PHD finger protein 14 7 10973872-11169630 Predicted intracellular proteins Evidence at protein level HPA000538 Supported Expressed in all Expressed in all parathyroid gland: 20.6 PHF2 CENP-35, JHDM1E, KIAA0662 ENSG00000197724 PHD finger protein 2 9 93576407-93679587 Predicted intracellular proteins Evidence at protein level HPA010831 Approved Supported Nucleus
Nucleoli
Cytosol Renal cancer:1.12e-5 (favourable), Colorectal cancer:9.34e-4 (unfavourable) Expressed in all Expressed in all endometrium: 30.6 PHF20 C20orf104, dJ1121G12.1, TDRD20A ENSG00000025293 PHD finger protein 20 20 35771974-35950381 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029619, HPA029620, HPA029621 Approved Supported Nucleoplasm
Nuclear membrane
Cytosol Liver cancer:2.49e-4 (unfavourable) Expressed in all Expressed in all testis: 26.0 PHF20L1 CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B ENSG00000129292 PHD finger protein 20-like 1 8 132775358-132848807 Predicted intracellular proteins Evidence at protein level HPA025060, HPA028417 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all thyroid gland: 37.9 PHF21A BHC80, BM-006, KIAA1696 ENSG00000135365 PHD finger protein 21A 11 45929323-46121178 Predicted intracellular proteins Evidence at protein level HPA023580 Uncertain Renal cancer:2.59e-8 (unfavourable), Liver cancer:1.66e-6 (unfavourable), Colorectal cancer:6.15e-4 (unfavourable) Expressed in all Expressed in all testis: 43.7 PHF23 FLJ16355, MGC2941 ENSG00000040633 PHD finger protein 23 17 7235028-7239722 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052410 Approved Validated Nucleoplasm Expressed in all Expressed in all testis: 41.7 PHF3 ENSG00000118482 PHD finger protein 3 6 63635820-63779336 Predicted intracellular proteins Evidence at protein level HPA024676, HPA025763 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 47.8 PHF5A bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7 ENSG00000100410 PHD finger protein 5A 22 41459717-41468725 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028885 Supported Validated Nucleoplasm Liver cancer:3.02e-8 (unfavourable) Expressed in all Expressed in all lymph node: 40.3 PHF6 BFLS, BORJ, CENP-31, KIAA1823, MGC14797 ENSG00000156531 PHD finger protein 6 X 134373253-134428791 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001023 Supported Validated Nucleus
Nucleoli Liver cancer:3.38e-4 (unfavourable), Pancreatic cancer:9.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.2 PHF8 JHDM1F, KIAA1111, ZNF422 ENSG00000172943 PHD finger protein 8 X 53936676-54048958 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038779, HPA062015 Approved Supported Nucleus Urothelial cancer:3.74e-5 (favourable) Expressed in all Expressed in all epididymis: 84.6 PHIP BRWD2, DCAF14, FLJ20705, ndrp, WDR11 ENSG00000146247 Pleckstrin homology domain interacting protein 6 78935867-79078236 Predicted intracellular proteins Evidence at protein level HPA019140, HPA019838 Approved Supported Nucleoplasm Renal cancer:1.71e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.9 PHKA2 PHK, PYK ENSG00000044446 Phosphorylase kinase, alpha 2 (liver) X 18892300-18984598 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA002912 Approved Approved Nucleoplasm Liver cancer:1.25e-5 (unfavourable), Renal cancer:1.55e-5 (unfavourable), Urothelial cancer:2.96e-5 (favourable), Pancreatic cancer:7.68e-4 (favourable) Expressed in all Expressed in all ovary: 18.5 PHKB ENSG00000102893 Phosphorylase kinase, beta 16 47461123-47701523 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA073380 Approved Golgi apparatus Renal cancer:3.89e-9 (favourable), Thyroid cancer:3.24e-4 (unfavourable), Colorectal cancer:3.69e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 97.5 PHKG2 ENSG00000156873 Phosphorylase kinase, gamma 2 (testis) 16 30748270-30761176 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065618, HPA068751 Supported Cytosol Lung cancer:1.90e-4 (favourable), Cervical cancer:7.90e-4 (favourable), Pancreatic cancer:8.02e-4 (favourable), Colorectal cancer:9.92e-4 (unfavourable) Expressed in all Expressed in all testis: 149.6 PHLDB3 FLJ40193 ENSG00000176531 Pleckstrin homology-like domain, family B, member 3 19 43474954-43504935 Predicted intracellular proteins Evidence at protein level HPA043425 Approved Approved Nuclear speckles
Plasma membrane
Cytosol Pancreatic cancer:6.36e-6 (favourable), Renal cancer:4.11e-5 (unfavourable), Stomach cancer:5.77e-4 (unfavourable) Expressed in all Expressed in all testis: 24.8 PHLPP1 KIAA0606, PHLPP, PLEKHE1, SCOP ENSG00000081913 PH domain and leucine rich repeat protein phosphatase 1 18 62715450-62980433 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020200 Uncertain Renal cancer:5.35e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 41.0 PHOSPHO2 MGC22679 ENSG00000144362 Phosphatase, orphan 2 2 169694454-169701708 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034726, HPA034727 Uncertain Approved Vesicles Liver cancer:3.82e-6 (unfavourable), Renal cancer:9.53e-4 (favourable) Expressed in all Expressed in all testis: 22.9 PHPT1 bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14 ENSG00000054148 Phosphohistidine phosphatase 1 9 136848724-136851027 Predicted intracellular proteins Evidence at protein level CAB013584, HPA020952 Approved Approved Nuclear bodies
Cytosol Expressed in all Expressed in all skeletal muscle: 71.6 PHYH PAHX, PHYH1, RD ENSG00000107537 Phytanoyl-CoA 2-hydroxylase 10 13277796-13302412 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007598, HPA011796 Approved Renal cancer:7.28e-12 (favourable) Expressed in all Expressed in all liver: 333.3 PHYHD1 MGC16638 ENSG00000175287 Phytanoyl-CoA dioxygenase domain containing 1 9 128920895-128942041 Predicted intracellular proteins Evidence at protein level HPA012115 Approved Nuclear speckles Renal cancer:6.38e-10 (favourable) Expressed in all Expressed in all cervix, uterine: 59.4 PHYKPL AGXT2L2, MGC15875 ENSG00000175309 5-phosphohydroxy-L-lysine phospho-lyase 5 178208497-178232791 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036461, HPA063608 Approved Approved Mitochondria Renal cancer:3.82e-5 (unfavourable) Expressed in all Expressed in all rectum: 35.8 PI4K2A DKFZP761G1923, PI4KII, PIK42A ENSG00000155252 Phosphatidylinositol 4-kinase type 2 alpha 10 97640686-97676434 Enzymes, Predicted intracellular proteins Evidence at protein level CAB030649, HPA076857 Approved Supported Plasma membrane Colorectal cancer:4.21e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.8 PI4KA PI4K-ALPHA, pi4K230, PIK4CA ENSG00000241973 Phosphatidylinositol 4-kinase, catalytic, alpha 22 20707691-20859417 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009092, HPA075515 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:7.22e-5 (favourable), Lung cancer:5.24e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 114.0 PI4KB PI4K-BETA, pi4K92, PIK4CB ENSG00000143393 Phosphatidylinositol 4-kinase, catalytic, beta 1 151291797-151327715 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006280, HPA006281, CAB022071 Approved Supported Golgi apparatus Pancreatic cancer:1.25e-5 (favourable), Liver cancer:2.97e-4 (unfavourable), Renal cancer:3.23e-4 (unfavourable), Thyroid cancer:6.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 101.2 PIAS1 DDXBP1, GBP, GU/RH-II, ZMIZ3 ENSG00000033800 Protein inhibitor of activated STAT, 1 15 68054179-68198603 Predicted intracellular proteins Evidence at protein level HPA005743, CAB012304 Supported Approved Microtubules Expressed in all Expressed in all testis: 37.6 PIAS3 FLJ14651, ZMIZ5 ENSG00000131788 Protein inhibitor of activated STAT, 3 1 145848522-145859836 Predicted intracellular proteins Evidence at protein level HPA006389, HPA067383 Approved Supported Nucleoplasm Renal cancer:1.21e-7 (unfavourable), Liver cancer:6.12e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 59.4 PIAS4 FLJ12419, Piasg, PIASY, ZMIZ6 ENSG00000105229 Protein inhibitor of activated STAT, 4 19 4007646-4039386 Predicted intracellular proteins Evidence at protein level HPA010598 Approved Approved Nucleoplasm Endometrial cancer:1.18e-5 (favourable), Pancreatic cancer:7.04e-4 (favourable) Expressed in all Expressed in all testis: 29.3 PIBF1 C13orf24, CEP90 ENSG00000083535 Progesterone immunomodulatory binding factor 1 13 72782059-73016461 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052269, HPA066120, HPA066125 Approved Supported Nucleoplasm
Microtubule organizing center Expressed in all Expressed in all testis: 25.7 PICALM CALM, CLTH ENSG00000073921 Phosphatidylinositol binding clathrin assembly protein 11 85957684-86069882 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019053, HPA019061 Supported Supported Vesicles Renal cancer:2.02e-6 (favourable), Pancreatic cancer:6.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 291.7 PICK1 dJ1039K5, MGC15204, PRKCABP ENSG00000100151 Protein interacting with PRKCA 1 22 38056311-38075701 Predicted intracellular proteins Evidence at protein level HPA067384, HPA072674 Approved Approved Mitochondria
Cytosol Stomach cancer:5.26e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 52.1 PID1 FLJ20701, NYGGF4 ENSG00000153823 Phosphotyrosine interaction domain containing 1 2 228850526-229271285 Predicted intracellular proteins Evidence at protein level HPA036103 Approved Approved Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 67.4 PIGBOS1 ENSG00000225973 PIGB opposite strand 1 15 55317184-55319161 Predicted intracellular proteins Evidence at transcript level Breast cancer:4.19e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.2 PIGC ENSG00000135845 Phosphatidylinositol glycan anchor biosynthesis, class C 1 172370189-172444086 Enzymes, Predicted membrane proteins Evidence at protein level HPA036663 Uncertain Renal cancer:1.43e-8 (unfavourable), Liver cancer:4.49e-4 (unfavourable) Expressed in all Expressed in all epididymis: 47.0 PIGF ENSG00000151665 Phosphatidylinositol glycan anchor biosynthesis, class F 2 46580937-46617119 Predicted membrane proteins Evidence at protein level HPA051389 Uncertain Liver cancer:1.39e-5 (unfavourable) Expressed in all Expressed in all testis: 47.8 PIGG FLJ20265, GPI7, LAS21 ENSG00000174227 Phosphatidylinositol glycan anchor biosynthesis, class G 4 499210-540196 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015997 Uncertain Uncertain Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 34.9 PIGH GPI-H ENSG00000100564 Phosphatidylinositol glycan anchor biosynthesis, class H 14 67581955-67600287 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031624 Approved Renal cancer:2.68e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 105.5 PIGK GPI8, hGPI8 ENSG00000142892 Phosphatidylinositol glycan anchor biosynthesis, class K 1 77088990-77219430 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA056383, HPA057040 Uncertain Liver cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.0 PIGL ENSG00000108474 Phosphatidylinositol glycan anchor biosynthesis, class L 17 16217191-16351797 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA012739 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.47e-4 (unfavourable), Prostate cancer:2.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 14.6 PIGN MDC4, PIG-N ENSG00000197563 Phosphatidylinositol glycan anchor biosynthesis, class N 18 62043567-62187118 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039922, HPA040374 Approved Supported Plasma membrane
Cytosol Colorectal cancer:6.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 31.3 PIGO DKFZp434M222, FLJ00135 ENSG00000165282 Phosphatidylinositol glycan anchor biosynthesis, class O 9 35088688-35096601 Disease related genes, Predicted membrane proteins Evidence at protein level HPA014905 Approved Nucleus
Nucleoli Renal cancer:3.05e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 73.2 PIGP DCRC, DSCR5, DSRC ENSG00000185808 Phosphatidylinositol glycan anchor biosynthesis, class P 21 37059170-37073170 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026921 Uncertain Approved Vesicles Expressed in all Expressed in all epididymis: 123.4 PIGQ GPI1, hGPI1 ENSG00000007541 Phosphatidylinositol glycan anchor biosynthesis, class Q 16 566995-584136 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039105, HPA039828, HPA061414 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:2.53e-6 (favourable) Expressed in all Expressed in all bone marrow: 24.2 PIGT ENSG00000124155 Phosphatidylinositol glycan anchor biosynthesis, class T 20 45416077-45426244 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Pancreatic cancer:2.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 158.8 PIGU bA346K17.2, CDC91L1, GAB1 ENSG00000101464 Phosphatidylinositol glycan anchor biosynthesis, class U 20 34560542-34698790 Predicted membrane proteins Evidence at protein level HPA041706, HPA046766 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:1.49e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 47.2 PIGV FLJ20477 ENSG00000060642 Phosphatidylinositol glycan anchor biosynthesis, class V 1 26787472-26798398 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054181 Approved Endoplasmic reticulum
Cytosol Renal cancer:7.60e-7 (favourable) Expressed in all Expressed in all testis: 83.5 PIGX FLJ20522 ENSG00000163964 Phosphatidylinositol glycan anchor biosynthesis, class X 3 196639775-196736007 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029409 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:7.45e-5 (unfavourable), Cervical cancer:2.12e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 28.0 PIH1D1 FLJ20643, NOP17 ENSG00000104872 PIH1 domain containing 1 19 49446298-49453497 Predicted intracellular proteins Evidence at protein level HPA047258 Approved Approved Cytosol Expressed in all Expressed in all fallopian tube: 64.2 PIK3C2A PI3K-C2alpha ENSG00000011405 Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 11 17077730-17207983 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037641, HPA037642 Uncertain Supported Nucleus Renal cancer:1.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 92.8 PIK3C3 Vps34 ENSG00000078142 Phosphatidylinositol 3-kinase, catalytic subunit type 3 18 41955206-42087830 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040718 Approved Renal cancer:4.97e-4 (favourable) Expressed in all Expressed in all testis: 33.0 PIK3CB PIK3C1 ENSG00000051382 Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 3 138652699-138834938 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB031938, HPA064207 Approved Supported Nucleoplasm
Nucleoli
Midbody Pancreatic cancer:3.99e-5 (unfavourable), Liver cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 88.7 PIK3IP1 HGFL, MGC17330 ENSG00000100100 Phosphoinositide-3-kinase interacting protein 1 22 31281593-31292534 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Urothelial cancer:3.80e-4 (favourable) Expressed in all Expressed in all lymph node: 122.7 PIK3R1 GRB1, p85, p85-ALPHA ENSG00000145675 Phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5 68215720-68301821 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001216, CAB004268 Approved Approved Cytosol Liver cancer:8.09e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 133.3 PIK3R2 p85, P85B ENSG00000105647 Phosphoinositide-3-kinase, regulatory subunit 2 (beta) 19 18153118-18170540 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA069291 Approved Approved Golgi apparatus Mixed Expressed in all cerebral cortex: 47.4 PIK3R4 p150, VPS15 ENSG00000196455 Phosphoinositide-3-kinase, regulatory subunit 4 3 130678935-130746829 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036032, HPA036033 Approved Approved Vesicles
Microtubules Renal cancer:4.40e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 45.7 PIKFYVE FAB1, KIAA0981, MGC40423, p235, PIKfyve, PIP5K, PIP5K3, ZFYVE29 ENSG00000115020 Phosphoinositide kinase, FYVE finger containing 2 208266267-208358751 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042604 Uncertain Uncertain Nuclear speckles Head and neck cancer:6.81e-4 (favourable) Expressed in all Expressed in all testis: 25.7 PILRB FDFACT1, FDFACT2 ENSG00000121716 Paired immunoglobin-like type 2 receptor beta 7 100352176-100367733 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026750 Approved Approved Mitochondria Renal cancer:1.42e-4 (unfavourable) Expressed in all Expressed in all testis: 167.1 PIM1 PIM ENSG00000137193 Pim-1 proto-oncogene, serine/threonine kinase 6 37170203-37175426 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA003941, CAB017040 Uncertain Supported Nucleoli
Cytosol Endometrial cancer:9.73e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 134.1 PIM3 ENSG00000198355 Pim-3 proto-oncogene, serine/threonine kinase 22 49960513-49964080 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA068758 Supported Cytosol Renal cancer:8.09e-4 (favourable), Ovarian cancer:9.68e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 61.3 PIN1 dod ENSG00000127445 Peptidylprolyl cis/trans isomerase, NIMA-interacting 1 19 9835257-9849682 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB004528, CAB009326, HPA068650 Approved Validated Nucleoplasm
Cytosol Renal cancer:7.80e-5 (favourable), Pancreatic cancer:3.25e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 137.3 PIN4 EPVH, PAR14, PAR17 ENSG00000102309 Peptidylprolyl cis/trans isomerase, NIMA-interacting 4 X 72181353-72302926 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054483, HPA064504 Approved Supported Nucleus
Nucleoli Testis cancer:2.58e-4 (favourable), Urothelial cancer:2.66e-4 (favourable), Lung cancer:6.37e-4 (favourable) Expressed in all Expressed in all epididymis: 24.0 PINK1 PARK6 ENSG00000158828 PTEN induced putative kinase 1 1 20633455-20651511 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001931, CAB026191 Uncertain Renal cancer:1.11e-16 (favourable) Expressed in all Expressed in all cerebral cortex: 145.9 PINX1 FLJ20565, LPTL, LPTS, MGC8850, PinX1 ENSG00000254093 PIN2/TERF1 interacting, telomerase inhibitor 1 8 10764963-10839884 Predicted intracellular proteins Evidence at protein level HPA023139 Uncertain Cervical cancer:2.45e-5 (favourable) Expressed in all Expressed in all testis: 16.0 PIP4K2A PIP5K2A, PIP5KIIA, PIP5KIIalpha ENSG00000150867 Phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 10 22534849-22714555 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA065440, HPA068771 Supported Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:1.46e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.6 PIP4K2B PIP5K2B, PIP5KIIB, PIP5KIIbeta ENSG00000276293 Phosphatidylinositol-5-phosphate 4-kinase, type II, beta 17 38765689-38800126 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA047875, HPA062220 Approved Supported Nucleoplasm Thyroid cancer:1.36e-4 (favourable), Liver cancer:4.54e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 51.8 PIP4K2C FLJ22055, PIP5K2C ENSG00000166908 Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 12 57591174-57603418 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028658, HPA058551 Approved Approved Vesicles Renal cancer:2.06e-6 (favourable), Liver cancer:7.98e-4 (unfavourable) Expressed in all Expressed in all epididymis: 107.2 PIP5K1A ENSG00000143398 Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1 151197949-151249536 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA029366 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:4.16e-7 (unfavourable) Expressed in all Expressed in all testis: 69.4 PIP5K1C KIAA0589, LCCS3, PIP5Kgamma ENSG00000186111 Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 19 3630183-3700479 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017168 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:7.28e-5 (favourable), Cervical cancer:1.79e-4 (favourable), Pancreatic cancer:2.32e-4 (favourable), Renal cancer:3.00e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 53.0 PISD dJ858B16.2, PSDC ENSG00000241878 Phosphatidylserine decarboxylase 22 31618491-31662432 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031090, HPA031091 Approved Approved Golgi apparatus
Cytosol Urothelial cancer:5.27e-5 (favourable) Expressed in all Expressed in all adipose tissue: 35.9 PITHD1 C1orf128, HT014, TXNL1CL ENSG00000057757 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 1 23778405-23788232 Predicted intracellular proteins Evidence at protein level HPA016936 Uncertain Expressed in all Expressed in all parathyroid gland: 205.1 PITPNA PITPN, VIB1A ENSG00000174238 Phosphatidylinositol transfer protein, alpha 17 1517718-1562816 Predicted intracellular proteins Evidence at protein level HPA000528 Uncertain Approved Vesicles
Cytosol Pancreatic cancer:1.80e-6 (favourable), Endometrial cancer:2.29e-4 (favourable), Renal cancer:9.35e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 118.3 PITPNB VIB1B ENSG00000180957 Phosphatidylinositol transfer protein, beta 22 27851669-27920134 Predicted intracellular proteins Evidence at protein level HPA000528 Uncertain Approved Vesicles
Cytosol Head and neck cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all placenta: 70.1 PITPNC1 RDGB-BETA, RDGBB, RDGBB1 ENSG00000154217 Phosphatidylinositol transfer protein, cytoplasmic 1 17 67377281-67697261 Predicted intracellular proteins Evidence at protein level HPA026563, HPA031250 Uncertain Approved Nucleoplasm
Cytosol Head and neck cancer:4.85e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 46.7 PITPNM1 DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1 ENSG00000110697 Phosphatidylinositol transfer protein, membrane-associated 1 11 67491768-67506263 Predicted intracellular proteins Evidence at protein level HPA060227, HPA062757 Approved Supported Cytosol
Cytoplasmic bodies Expressed in all Expressed in all fallopian tube: 36.7 PITRM1 hMP1, KIAA1104, MP1, PreP ENSG00000107959 Pitrilysin metallopeptidase 1 10 3137728-3172841 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006753, HPA006754 Supported Supported Mitochondria Expressed in all Expressed in all testis: 87.9 PJA1 FLJ11830, RNF70 ENSG00000181191 Praja ring finger 1, E3 ubiquitin protein ligase X 69160851-69165793 Predicted intracellular proteins Evidence at protein level HPA000595 Approved Approved Nucleus
Nucleoli Renal cancer:7.44e-5 (favourable) Expressed in all Expressed in all epididymis: 178.2 PJA2 KIAA0438, Neurodap1, RNF131 ENSG00000198961 Praja ring finger 2, E3 ubiquitin protein ligase 5 109334709-109409994 Predicted intracellular proteins Evidence at protein level HPA040347, HPA057636 Supported Supported Intermediate filaments Ovarian cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 255.1 PKD2 Pc-2, PC2, PKD4, TRPP2 ENSG00000118762 Polycystic kidney disease 2 (autosomal dominant) 4 88007668-88077777 Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level CAB004544, HPA015794 Approved Validated Endoplasmic reticulum Expressed in all Expressed in all endometrium: 100.4 PKIG ENSG00000168734 Protein kinase (cAMP-dependent, catalytic) inhibitor gamma 20 44531785-44624247 Predicted intracellular proteins Evidence at protein level HPA042703, HPA063690 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:4.90e-5 (favourable) Expressed in all Expressed in all heart muscle: 176.3 PKM OIP3, PK3, PKM2, THBP1 ENSG00000067225 Pyruvate kinase, muscle 15 72199029-72231822 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB019421, HPA029501 Uncertain Validated Cytosol Liver cancer:2.74e-6 (unfavourable), Pancreatic cancer:5.17e-5 (unfavourable), Head and neck cancer:1.30e-4 (unfavourable), Lung cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 1492.7 PKN1 DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1 ENSG00000123143 Protein kinase N1 19 14433053-14471867 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003982, CAB010278 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all Expressed in all spleen: 87.5 PKN2 Pak-2, PRK2, PRKCL2, STK7 ENSG00000065243 Protein kinase N2 1 88684222-88836255 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034861 Uncertain Colorectal cancer:5.67e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 48.2 PKP4 p0071 ENSG00000144283 Plakophilin 4 2 158456964-158682879 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037334, HPA066647, HPA070648 Approved Validated Plasma membrane
Cell Junctions Renal cancer:3.29e-7 (favourable), Endometrial cancer:5.80e-4 (favourable) Expressed in all Expressed in all kidney: 65.1 PLA2G12A PLA2G12 ENSG00000123739 Phospholipase A2, group XIIA 4 109709989-109730077 Enzymes, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level HPA035908, HPA035909 Approved Renal cancer:2.54e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 33.6 PLA2G15 GXVPLA2, LLPL, LYPLA3 ENSG00000103066 Phospholipase A2, group XV 16 68245304-68261062 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041702, HPA041727 Supported Approved Nucleoplasm
Vesicles Expressed in all Expressed in all placenta: 37.3 PLA2G16 AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754. ENSG00000176485 Phospholipase A2, group XVI 11 63573195-63616883 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA058997 Uncertain Approved Mitochondria Pancreatic cancer:5.58e-6 (unfavourable), Thyroid cancer:2.54e-5 (favourable) Expressed in all Expressed in all adipose tissue: 327.0 PLA2G6 iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9 ENSG00000184381 Phospholipase A2, group VI (cytosolic, calcium-independent) 22 38111495-38205690 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins Evidence at protein level HPA001171 Approved Approved Microtubule organizing center
Cytosol Urothelial cancer:1.55e-4 (favourable), Cervical cancer:7.29e-4 (favourable) Expressed in all Expressed in all testis: 60.3 PLAA DOA1, FLJ11281, FLJ12699, PLA2P, PLAP ENSG00000137055 Phospholipase A2-activating protein 9 26904083-26947463 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005035, HPA020994, HPA020996 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Ovarian cancer:7.87e-4 (favourable) Expressed in all Expressed in all testis: 37.8 PLAGL1 LOT1, ZAC ENSG00000118495 Pleiomorphic adenoma gene-like 1 6 143940300-144064599 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055706 Supported Nuclear bodies
Golgi apparatus
Vesicles Renal cancer:4.94e-6 (unfavourable), Stomach cancer:6.61e-4 (unfavourable) Mixed Expressed in all placenta: 362.2 PLAGL2 ZNF900 ENSG00000126003 Pleiomorphic adenoma gene-like 2 20 32192503-32207791 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005900 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 25.7 PLAU UPA, URK ENSG00000122861 Plasminogen activator, urokinase 10 73909177-73917497 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008719 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:1.32e-4 (unfavourable), Head and neck cancer:2.70e-4 (unfavourable), Endometrial cancer:3.38e-4 (favourable), Renal cancer:3.51e-4 (unfavourable), Lung cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all appendix: 61.3 PLAUR CD87, UPAR, URKR ENSG00000011422 Plasminogen activator, urokinase receptor 19 43646095-43670547 Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050843, CAB073533 Uncertain Supported Plasma membrane Renal cancer:7.83e-9 (unfavourable), Lung cancer:2.33e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 429.4 PLBD1 FLJ22662 ENSG00000121316 Phospholipase B domain containing 1 12 14503661-14568349 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040303 Approved Liver cancer:2.81e-5 (unfavourable), Pancreatic cancer:1.66e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 167.6 PLBD2 p76 ENSG00000151176 Phospholipase B domain containing 2 12 113358566-113391625 Predicted secreted proteins Evidence at protein level HPA017163 Approved Renal cancer:3.58e-11 (unfavourable) Expressed in all Expressed in all adrenal gland: 109.8 PLCB3 ENSG00000149782 Phospholipase C, beta 3 (phosphatidylinositol-specific) 11 64251523-64269150 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009257, HPA039279, HPA043907 Supported Validated Nucleoplasm Renal cancer:4.31e-5 (unfavourable), Liver cancer:1.39e-4 (unfavourable) Expressed in all Expressed in all duodenum: 118.1 PLCG1 NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1 ENSG00000124181 Phospholipase C, gamma 1 20 41136960-41196801 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004277, HPA036681, HPA036682 Approved Supported Cytosol Pancreatic cancer:4.72e-4 (favourable) Expressed in all Expressed in all endometrium: 47.4 PLCL2 KIAA1092, PLCE2 ENSG00000154822 Phospholipase C-like 2 3 16802651-17090594 Predicted intracellular proteins Evidence at protein level HPA047616 Uncertain Renal cancer:2.98e-10 (favourable) Expressed in all Expressed in all ovary: 30.4 PLCXD1 FLJ11323 ENSG00000182378 Phosphatidylinositol-specific phospholipase C, X domain containing 1 X 276322-303356 Predicted intracellular proteins Evidence at protein level HPA007721 Approved Approved Cytosol Renal cancer:7.82e-14 (unfavourable), Head and neck cancer:2.50e-4 (favourable), Endometrial cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all stomach: 26.3 PLD2 ENSG00000129219 Phospholipase D2 17 4807096-4823434 Enzymes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA013397 Approved Expressed in all Expressed in all esophagus: 42.6 PLD3 HU-K4 ENSG00000105223 Phospholipase D family, member 3 19 40348456-40380439 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012800, CAB020812 Approved Renal cancer:2.21e-4 (favourable), Pancreatic cancer:6.44e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 496.2 PLEC EBS1, PCN, PLEC1, PLTN ENSG00000178209 Plectin 8 143915147-143976734 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003847, HPA025967, HPA029906 Supported Validated Intermediate filaments
Focal adhesion sites
Cytosol Renal cancer:7.98e-6 (unfavourable), Colorectal cancer:4.29e-4 (unfavourable), Lung cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 94.9 PLEKHA1 TAPP1 ENSG00000107679 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 10 122374696-122442602 Predicted intracellular proteins Evidence at protein level HPA002043, HPA064795 Approved Validated Nucleus
Cytosol Expressed in all Expressed in all skin: 79.5 PLEKHA2 TAPP2 ENSG00000169499 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 8 38901235-38973909 Predicted intracellular proteins Evidence at protein level HPA004706 Approved Uncertain Nucleus
Nuclear bodies
Cytosol Renal cancer:1.95e-6 (unfavourable) Expressed in all Expressed in all lymph node: 92.9 PLEKHA5 FLJ10667, KIAA1686, PEPP2 ENSG00000052126 Pleckstrin homology domain containing, family A member 5 12 19129752-19376400 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035923, HPA035924, HPA041455 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:5.41e-5 (unfavourable), Renal cancer:7.42e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 54.4 PLEKHB2 EVT2, FLJ20783 ENSG00000115762 Pleckstrin homology domain containing, family B (evectins) member 2 2 131104847-131353709 Predicted intracellular proteins Evidence at protein level Renal cancer:1.72e-8 (favourable), Liver cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 125.6 PLEKHF2 FLJ13187, PHAFIN2, ZFYVE18 ENSG00000175895 Pleckstrin homology domain containing, family F (with FYVE domain) member 2 8 95133804-95156684 Predicted intracellular proteins Evidence at protein level HPA024829 Uncertain Renal cancer:1.49e-4 (favourable) Expressed in all Expressed in all lymph node: 63.4 PLEKHG2 ARHGEF42, CLG, FLJ00018 ENSG00000090924 Pleckstrin homology domain containing, family G (with RhoGef domain) member 2 19 39412585-39428415 Predicted intracellular proteins Evidence at protein level HPA017973, HPA048054 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.79e-8 (unfavourable), Colorectal cancer:3.53e-4 (unfavourable) Expressed in all Expressed in all placenta: 33.0 PLEKHG3 ARHGEF43, KIAA0599 ENSG00000126822 Pleckstrin homology domain containing, family G (with RhoGef domain) member 3 14 64704102-64750247 Predicted intracellular proteins Evidence at protein level HPA063455, HPA065323 Supported Nucleoplasm
Plasma membrane
Cytokinetic bridge
Centrosome
Cytosol Renal cancer:7.39e-8 (favourable) Expressed in all Expressed in all seminal vesicle: 52.5 PLEKHH3 FLJ21019 ENSG00000068137 Pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 17 42667914-42676994 Predicted intracellular proteins Evidence at protein level HPA046234 Uncertain Approved Golgi apparatus Renal cancer:9.62e-5 (unfavourable) Expressed in all Expressed in all skin: 11.6 PLEKHJ1 FLJ10297 ENSG00000104886 Pleckstrin homology domain containing, family J member 1 19 2230084-2237704 Predicted intracellular proteins Evidence at protein level HPA048989 Approved Approved Mitochondria Renal cancer:1.10e-5 (favourable), Stomach cancer:6.99e-4 (favourable) Expressed in all Expressed in all duodenum: 110.9 PLEKHM2 KIAA0842 ENSG00000116786 Pleckstrin homology domain containing, family M (with RUN domain) member 2 1 15684332-15734769 Predicted intracellular proteins Evidence at protein level HPA032304 Approved Liver cancer:1.36e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 50.1 PLEKHO2 DKFZp761K2312, PLEKHQ1, PP1628, pp9099 ENSG00000241839 Pleckstrin homology domain containing, family O member 2 15 64841883-64868007 Predicted intracellular proteins Evidence at protein level HPA040055 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all spleen: 121.4 PLGRKT AD025, C9orf46, FLJ14688, MDS030, Plg-RKT ENSG00000107020 Plasminogen receptor, C-terminal lysine transmembrane protein 9 5357973-5437878 Predicted intracellular proteins Evidence at protein level HPA008214, HPA011144 Approved Uncertain Mitochondria Renal cancer:5.09e-5 (favourable), Breast cancer:5.56e-4 (favourable) Expressed in all Expressed in all rectum: 56.0 PLIN2 ADFP, ADRP ENSG00000147872 Perilipin 2 9 19108375-19149290 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016607, CAB037331 Supported Supported Lipid droplets Thyroid cancer:2.16e-4 (favourable), Renal cancer:3.32e-4 (unfavourable) Group enriched Expressed in all liver: 450.0 PLIN3 M6PRBP1, PP17, TIP47 ENSG00000105355 Perilipin 3 19 4838341-4867768 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006427, HPA066538 Uncertain Validated Lipid droplets
Cytosol Renal cancer:9.15e-7 (unfavourable), Lung cancer:7.67e-6 (unfavourable), Liver cancer:3.27e-5 (unfavourable), Endometrial cancer:2.62e-4 (favourable) Expressed in all Expressed in all esophagus: 116.2 PLK2 SNK ENSG00000145632 Polo-like kinase 2 5 58453982-58460260 Enzymes, Predicted intracellular proteins Evidence at protein level CAB009624, HPA069329 Approved Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:2.08e-4 (unfavourable) Expressed in all Expressed in all spleen: 97.3 PLLP PMLP, TM4SF11 ENSG00000102934 Plasmolipin 16 57248547-57284687 Predicted membrane proteins Evidence at protein level HPA041862 Supported Renal cancer:6.21e-9 (favourable), Endometrial cancer:2.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 118.4 PLOD1 LH1, LLH, PLOD ENSG00000083444 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1 11934205-11975538 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA049137, HPA055799 Uncertain Uncertain Nucleoplasm
Vesicles Renal cancer:1.91e-12 (unfavourable), Urothelial cancer:2.43e-4 (unfavourable), Liver cancer:2.79e-4 (unfavourable) Expressed in all Expressed in all placenta: 121.3 PLOD3 LH3 ENSG00000106397 Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 7 101205977-101218420 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001236 Uncertain Cervical cancer:1.91e-5 (unfavourable), Colorectal cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all placenta: 48.0 PLP2 A4, A4-LSB, MGC126187 ENSG00000102007 Proteolipid protein 2 (colonic epithelium-enriched) X 49171926-49175239 Predicted membrane proteins, Transporters Evidence at protein level HPA042415 Approved Renal cancer:5.55e-10 (unfavourable), Endometrial cancer:3.32e-5 (unfavourable) Expressed in all Expressed in all skin: 480.7 PLPP3 LPP3, PAP-2b, PPAP2B ENSG00000162407 Phospholipid phosphatase 3 1 56494747-56645301 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA028892, HPA072751 Uncertain Supported Golgi apparatus Renal cancer:4.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 543.7 PLPP5 DPPL1, HTPAP, PPAPDC1B ENSG00000147535 Phospholipid phosphatase 5 8 38263130-38269243 Enzymes, Predicted membrane proteins Evidence at protein level HPA055777 Approved Vesicles Renal cancer:8.33e-10 (unfavourable), Endometrial cancer:1.48e-5 (favourable), Ovarian cancer:2.42e-5 (favourable), Lung cancer:8.72e-5 (favourable) Expressed in all Expressed in all prostate: 123.7 PLPPR2 LPPR2, PRG-4 ENSG00000105520 Phospholipid phosphatase related 2 19 11355386-11365698 Enzymes, Predicted membrane proteins Evidence at protein level HPA048973 Uncertain Approved Nucleoplasm Renal cancer:7.46e-11 (unfavourable), Colorectal cancer:6.45e-4 (unfavourable), Pancreatic cancer:6.82e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 77.4 PLRG1 Cwc1, PRL1, Prp46, PRPF46, TANGO4 ENSG00000171566 Pleiotropic regulator 1 4 154535006-154550435 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035931, HPA035932, HPA061486 Supported Validated Nuclear membrane
Nuclear speckles Renal cancer:8.20e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 65.7 PLSCR1 MMTRA1B ENSG00000188313 Phospholipid scramblase 1 3 146515180-146544864 Predicted intracellular proteins, Transporters Evidence at protein level HPA068923, CAB070421 Approved Approved Nucleus
Golgi apparatus
Plasma membrane Endometrial cancer:1.35e-4 (unfavourable) Expressed in all Expressed in all appendix: 117.3 PLSCR4 ENSG00000114698 Phospholipid scramblase 4 3 146192339-146251179 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002276 Approved Approved Nucleoplasm
Nuclear bodies Endometrial cancer:3.90e-4 (unfavourable), Renal cancer:4.13e-4 (unfavourable) Expressed in all Expressed in all placenta: 79.5 PLTP BPIFE ENSG00000100979 Phospholipid transfer protein 20 45898621-45912155 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB032873 Approved Renal cancer:9.52e-8 (unfavourable) Expressed in all Expressed in all placenta: 630.8 PLVAP FELS, gp68, PV-1, PV1 ENSG00000130300 Plasmalemma vesicle associated protein 19 17351448-17377350 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002279 Supported Uncertain Cytosol Expressed in all Expressed in all thyroid gland: 328.6 PLXNB2 KIAA0315, MM1, PLEXB2 ENSG00000196576 Plexin B2 22 50274979-50307627 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA003100 Uncertain Stomach cancer:4.75e-4 (favourable), Ovarian cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all spleen: 123.1 PLXND1 KIAA0620 ENSG00000004399 Plexin D1 3 129555175-129606818 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB020819 Approved Renal cancer:5.93e-7 (unfavourable) Expressed in all Expressed in all placenta: 159.8 PM20D2 ACY1L2, bA63L7.3 ENSG00000146281 Peptidase M20 domain containing 2 6 89146050-89165565 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030325, HPA030326, HPA030327 Approved Validated Nucleoplasm Expressed in all Expressed in all prostate: 39.3 PMF1 ENSG00000160783 Polyamine-modulated factor 1 1 156212993-156240042 Predicted intracellular proteins Evidence at protein level HPA034583, HPA071854 Supported Nucleoplasm
Vesicles Expressed in all Expressed in all thyroid gland: 68.4 PML MYL, RNF71, TRIM19 ENSG00000140464 Promyelocytic leukemia 15 73994673-74047812 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008312, CAB010194, CAB016304 Supported Validated Nuclear bodies Renal cancer:6.27e-8 (unfavourable), Breast cancer:3.24e-4 (favourable), Pancreatic cancer:3.29e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 45.0 PMM1 Sec53 ENSG00000100417 Phosphomannomutase 1 22 41576894-41589890 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030712 Uncertain Endometrial cancer:6.09e-6 (favourable), Pancreatic cancer:2.05e-4 (favourable), Cervical cancer:5.92e-4 (favourable) Expressed in all Expressed in all ovary: 54.9 PMM2 CDG1, CDG1a, CDGS, PMI, PMI1 ENSG00000140650 Phosphomannomutase 2 16 8788823-8849331 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040852, HPA063649 Approved Nucleus
Cytosol Renal cancer:8.97e-6 (unfavourable), Colorectal cancer:1.04e-4 (favourable) Expressed in all Expressed in all rectum: 28.8 PMP22 GAS3, HNPP, Sp110 ENSG00000109099 Peripheral myelin protein 22 17 15229777-15265326 Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all placenta,small intestine: 314.4 PMPCA Alpha-MPP, INPP5E, KIAA0123 ENSG00000165688 Peptidase (mitochondrial processing) alpha 9 136410570-136423761 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021648, HPA063735 Supported Validated Mitochondria Renal cancer:2.14e-6 (favourable), Pancreatic cancer:8.00e-5 (favourable) Expressed in all Expressed in all adrenal gland: 38.8 PMPCB MPPB, MPPP52 ENSG00000105819 Peptidase (mitochondrial processing) beta 7 103297422-103329511 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040674, HPA074168 Approved Supported Mitochondria Renal cancer:2.95e-8 (favourable), Breast cancer:2.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 68.9 PMS1 MLH2, PMSL1 ENSG00000064933 PMS1 homolog 1, mismatch repair system component 2 189784085-189877629 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010233, HPA031013 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:1.86e-6 (unfavourable), Liver cancer:2.38e-6 (unfavourable), Urothelial cancer:3.73e-4 (favourable) Expressed in all Expressed in all testis: 84.8 PMVK HUMPMKI, PMK, PMKA ENSG00000163344 Phosphomevalonate kinase 1 154924734-154936991 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029900 Approved Renal cancer:4.96e-4 (favourable), Ovarian cancer:9.70e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 55.4 PNISR bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130 ENSG00000132424 PNN-interacting serine/arginine-rich protein 6 99398051-99425331 Predicted intracellular proteins Evidence at protein level HPA038796 Uncertain Supported Nuclear speckles
Cytosol Urothelial cancer:1.09e-4 (favourable), Renal cancer:1.41e-4 (unfavourable), Pancreatic cancer:5.27e-4 (favourable) Expressed in all Expressed in all endometrium: 126.6 PNKD BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, PDC, PKND1, TAHCCP2 ENSG00000127838 Paroxysmal nonkinesigenic dyskinesia 2 218270392-218346793 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010134, HPA017068 Approved Validated Mitochondria Renal cancer:5.13e-5 (unfavourable) Expressed in all Expressed in all prostate: 117.3 PNKP PNK ENSG00000039650 Polynucleotide kinase 3'-phosphatase 19 49861204-49878351 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006782 Supported Supported Nucleus
Nucleoli Breast cancer:9.18e-4 (favourable) Expressed in all Expressed in all spleen: 30.5 PNMA1 MA1 ENSG00000176903 Paraneoplastic Ma antigen 1 14 73711783-73714372 Predicted intracellular proteins Evidence at protein level HPA003817, HPA015007 Supported Supported Focal adhesion sites
Cytosol Liver cancer:3.00e-5 (unfavourable), Urothelial cancer:4.51e-5 (unfavourable), Head and neck cancer:7.49e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 194.0 PNN memA ENSG00000100941 Pinin, desmosome associated protein 14 39175183-39183218 Predicted intracellular proteins, Transporters Evidence at protein level HPA001378 Supported Validated Nuclear speckles Prostate cancer:2.44e-4 (unfavourable), Liver cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all epididymis: 141.4 PNO1 KHRBP1, RRP20 ENSG00000115946 Partner of NOB1 homolog 2 68157844-68176238 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056928 Supported Nucleus
Nucleoli Liver cancer:3.04e-8 (unfavourable), Endometrial cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 20.7 PNP NP, PUNP ENSG00000198805 Purine nucleoside phosphorylase 14 20468954-20477094 Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001625 Supported Renal cancer:2.24e-4 (favourable), Liver cancer:4.43e-4 (unfavourable) Expressed in all Expressed in all epididymis: 686.0 PNPLA4 DXS1283E, GS2, iPLA2eta ENSG00000006757 Patatin-like phospholipase domain containing 4 X 7898247-7927739 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003656 Approved Renal cancer:2.23e-12 (favourable), Glioma:4.67e-4 (unfavourable), Head and neck cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.3 PNPLA6 iPLA2delta, NTE, SPG39, sws ENSG00000032444 Patatin-like phospholipase domain containing 6 19 7534004-7561764 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA007522 Uncertain Pancreatic cancer:3.51e-5 (favourable), Head and neck cancer:5.25e-4 (favourable), Renal cancer:7.53e-4 (favourable) Expressed in all Expressed in all testis: 49.2 PNPLA8 IPLA2-2, IPLA2G, iPLA2gamma ENSG00000135241 Patatin-like phospholipase domain containing 8 7 108470422-108569666 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020083 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:1.86e-6 (favourable) Expressed in all Expressed in all adrenal gland: 63.4 PNPO PDXPO ENSG00000108439 Pyridoxamine 5'-phosphate oxidase 17 47941506-47948288 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA023204, HPA027776 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all liver: 51.2 PNPT1 DFNB70, old-35, OLD35, PNPase ENSG00000138035 Polyribonucleotide nucleotidyltransferase 1 2 55634265-55693910 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033424, HPA034602, HPA034603 Supported Validated Mitochondria Liver cancer:1.95e-7 (unfavourable), Pancreatic cancer:5.44e-5 (unfavourable), Endometrial cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 10.0 PNRC1 B4-2, PROL2, PRR2 ENSG00000146278 Proline-rich nuclear receptor coactivator 1 6 89080751-89085160 Predicted intracellular proteins Evidence at protein level HPA029839, HPA066513 Approved Approved Nucleus
Nucleoli Renal cancer:6.88e-6 (unfavourable) Expressed in all Expressed in all ovary: 271.2 PNRC2 ENSG00000189266 Proline-rich nuclear receptor coactivator 2 1 23959109-23963462 Predicted intracellular proteins Evidence at protein level HPA027820, HPA045837 Uncertain Supported Nucleoplasm
Golgi apparatus Liver cancer:7.97e-5 (unfavourable), Melanoma:1.41e-4 (unfavourable), Urothelial cancer:4.05e-4 (favourable), Breast cancer:6.02e-4 (favourable) Expressed in all Expressed in all thyroid gland: 202.7 POC1B FLJ14923, TUWD12, WDR51B ENSG00000139323 POC1 centriolar protein B 12 89419718-89526024 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038841 Approved Renal cancer:3.45e-6 (favourable), Endometrial cancer:9.59e-5 (favourable) Expressed in all Expressed in all fallopian tube: 19.7 POFUT1 FUT12, KIAA0180, O-Fuc-T, O-FUT ENSG00000101346 Protein O-fucosyltransferase 1 20 32207880-32238667 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA054519, HPA059935 Approved Approved Centrosome Expressed in all Expressed in all parathyroid gland: 35.1 POFUT2 C21orf80, FUT13, KIAA0958 ENSG00000186866 Protein O-fucosyltransferase 2 21 45263928-45287898 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044297 Uncertain Renal cancer:8.66e-12 (unfavourable), Colorectal cancer:4.55e-7 (unfavourable), Liver cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all placenta: 24.2 POGK BASS2, KIAA15131, KRBOX2, LST003 ENSG00000143157 Pogo transposable element with KRAB domain 1 166839447-166856344 Predicted intracellular proteins Evidence at protein level HPA007838, HPA031630 Approved Supported Nucleoplasm
Vesicles Liver cancer:5.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.5 POGZ KIAA0461, ZNF280E, ZNF635m ENSG00000143442 Pogo transposable element with ZNF domain 1 151402724-151459465 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006800, HPA008781 Approved Validated Nucleoplasm Renal cancer:3.92e-5 (unfavourable), Urothelial cancer:4.40e-4 (favourable), Endometrial cancer:8.67e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.9 POLB ENSG00000070501 Polymerase (DNA directed), beta 8 42338454-42371808 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011616, HPA049104 Supported Approved Vesicles Renal cancer:2.15e-5 (unfavourable), Endometrial cancer:1.46e-4 (unfavourable), Urothelial cancer:5.65e-4 (favourable) Expressed in all Expressed in all testis: 92.3 POLD2 ENSG00000106628 Polymerase (DNA directed), delta 2, accessory subunit 7 44114681-44124358 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026745 Approved Validated Nucleoplasm Expressed in all Expressed in all fallopian tube: 121.0 POLD3 KIAA0039, P66, P68, PPP1R128 ENSG00000077514 Polymerase (DNA-directed), delta 3, accessory subunit 11 74493851-74669117 Predicted intracellular proteins Evidence at protein level HPA058846 Supported Supported Nucleus Renal cancer:7.90e-6 (unfavourable), Melanoma:5.48e-4 (unfavourable), Liver cancer:9.17e-4 (unfavourable) Expressed in all Expressed in all kidney: 45.2 POLD4 p12, POLDS ENSG00000175482 Polymerase (DNA-directed), delta 4, accessory subunit 11 67350777-67356972 Predicted intracellular proteins Evidence at protein level HPA071529 Uncertain Nucleus
Nucleoli
Mitochondria
Cytosol Expressed in all Expressed in all small intestine: 122.5 POLDIP2 DKFZP586F1524, PDIP38 ENSG00000004142 Polymerase (DNA-directed), delta interacting protein 2 17 28347177-28357522 Predicted intracellular proteins Evidence at protein level HPA007700 Approved Mitochondria Expressed in all Expressed in all kidney: 108.5 POLDIP3 KIAA1649, PDIP46 ENSG00000100227 Polymerase (DNA-directed), delta interacting protein 3 22 42583721-42614962 Predicted intracellular proteins Evidence at protein level HPA018419, HPA048790 Approved Validated Nuclear speckles
Cytoplasmic bodies Renal cancer:3.36e-4 (favourable), Glioma:6.67e-4 (favourable) Expressed in all Expressed in all ovary: 109.4 POLE POLE1 ENSG00000177084 Polymerase (DNA directed), epsilon, catalytic subunit 12 132623753-132687365 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058210, HPA067385 Validated Nucleus
Plasma membrane Renal cancer:3.19e-8 (unfavourable), Melanoma:1.44e-4 (unfavourable) Expressed in all Expressed in all testis: 22.0 POLE3 CHARAC17, CHRAC17, p17, Ybl1 ENSG00000148229 Polymerase (DNA directed), epsilon 3, accessory subunit 9 113407235-113410672 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA047945 Uncertain Approved Nucleus
Nucleoli Liver cancer:8.35e-4 (unfavourable) Expressed in all Expressed in all testis: 76.2 POLE4 p12 ENSG00000115350 Polymerase (DNA-directed), epsilon 4, accessory subunit 2 74958492-74970128 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA054979, HPA071815 Approved Approved Nucleus
Cytosol Liver cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 12.7 POLG POLG1, POLGA ENSG00000140521 Polymerase (DNA directed), gamma 15 89316305-89334861 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA056821 Approved Prostate cancer:5.73e-4 (unfavourable) Expressed in all Expressed in all spleen: 21.6 POLH RAD30A, XP-V ENSG00000170734 Polymerase (DNA directed), eta 6 43576150-43615660 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA006721, HPA026762 Approved Validated Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 21.0 POLI RAD30B, RAD3OB ENSG00000101751 Polymerase (DNA directed) iota 18 54269404-54321266 Enzymes, Predicted intracellular proteins Evidence at protein level HPA012000, HPA064696 Supported Supported Nuclear speckles
Cytoplasmic bodies Expressed in all Expressed in all testis: 69.3 POLL ENSG00000166169 Polymerase (DNA directed), lambda 10 101578882-101588270 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA066704 Approved Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 49.7 POLM Tdt-N ENSG00000122678 Polymerase (DNA directed), mu 7 44072247-44082540 Enzymes, Predicted intracellular proteins Evidence at protein level HPA058900, HPA066007 Supported Nucleus Expressed in all Expressed in all spleen: 11.1 POLR1A DKFZP586M0122, FLJ21915, RPA1, RPO1-4 ENSG00000068654 Polymerase (RNA) I polypeptide A, 194kDa 2 86020216-86106155 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level CAB010145, HPA031513, HPA049700 Supported Supported Nucleus
Nucleoli fibrillar center Liver cancer:3.70e-9 (unfavourable), Ovarian cancer:3.37e-4 (unfavourable), Thyroid cancer:8.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.1 POLR1B FLJ10816, FLJ21921, RPA2, Rpo1-2 ENSG00000125630 Polymerase (RNA) I polypeptide B, 128kDa 2 112541915-112577150 Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037528 Supported Nucleoli
Cytosol Endometrial cancer:2.71e-5 (unfavourable), Pancreatic cancer:5.52e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.6 POLR1C RPA39, RPA40, RPA5, RPAC1 ENSG00000171453 Polymerase (RNA) I polypeptide C, 30kDa 6 43509702-43529585 Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA031010 Supported Nucleus Renal cancer:4.17e-4 (unfavourable) Expressed in all Expressed in all testis: 34.4 POLR1D MGC9850, RPA16, RPA9, RPAC2, RPO1-3 ENSG00000186184 Polymerase (RNA) I polypeptide D, 16kDa 13 27620742-27667415 Disease related genes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA039337 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all testis: 107.5 POLR1E FLJ13390, FLJ13970, PAF53, PRAF1 ENSG00000137054 Polymerase (RNA) I polypeptide E, 53kDa 9 37485935-37503697 Predicted intracellular proteins, Predicted membrane proteins, RNA polymerase related proteins Evidence at protein level HPA022527, HPA052400 Supported Supported Nucleus
Nucleoli fibrillar center Breast cancer:2.27e-4 (favourable) Expressed in all Expressed in all ovary: 51.4 POLR2A POLR2, POLRA, RPB1 ENSG00000181222 Polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 17 7484366-7514618 Enzymes, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level CAB012226, CAB016388, HPA021563, CAB022311, HPA053012 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 117.8 POLR2B RPB2 ENSG00000047315 Polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 4 56977722-57031168 Enzymes, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037506 Supported Supported Nucleoplasm Renal cancer:7.17e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 82.8 POLR2C RPB3 ENSG00000102978 Polymerase (RNA) II (DNA directed) polypeptide C, 33kDa 16 57462387-57472010 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA040919, HPA041826 Approved Supported Nucleoplasm
Microtubules
Cytosol Renal cancer:3.03e-6 (favourable), Head and neck cancer:1.48e-4 (unfavourable) Expressed in all Expressed in all epididymis: 67.0 POLR2E hRPB25, hsRPB5, RPABC1, RPB5, XAP4 ENSG00000099817 Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 19 1086579-1095380 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA063030, HPA068992 Supported Supported Nucleoplasm Renal cancer:3.21e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 42.0 POLR2F HRBP14.4, RPB6 ENSG00000100142 Polymerase (RNA) II (DNA directed) polypeptide F 22 37952607-38041915 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA000827, CAB009882 Supported Validated Nucleus
Nucleoli fibrillar center Tissue enhanced Expressed in all cerebral cortex: 121.0 POLR2G hRPB19, hsRPB7, RPB7 ENSG00000168002 Polymerase (RNA) II (DNA directed) polypeptide G 11 62761544-62766710 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA053000 Approved Supported Nucleoplasm Liver cancer:6.02e-5 (unfavourable), Renal cancer:1.11e-4 (unfavourable), Endometrial cancer:8.23e-4 (favourable) Expressed in all Expressed in all fallopian tube: 98.6 POLR2H RPB8 ENSG00000163882 Polymerase (RNA) II (DNA directed) polypeptide H 3 184361718-184368596 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037745, HPA055813 Supported Supported Nucleus Renal cancer:1.65e-10 (unfavourable), Liver cancer:2.01e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 71.3 POLR2I hRPB14.5, RPB9 ENSG00000105258 Polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 19 36113710-36115346 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA035632, HPA045156 Uncertain Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 18.5 POLR2J hRPB14, POLR2J1, RPB11, RPB11A, RPB11m ENSG00000005075 Polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 7 102473118-102478907 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA042997, HPA044010, HPA046970 Approved Approved Nucleoplasm Expressed in all Expressed in all adrenal gland: 73.5 POLR2J3 ENSG00000168255 Polymerase (RNA) II (DNA directed) polypeptide J3 7 102537918-102572656 Predicted intracellular proteins, RNA polymerase related proteins Evidence at transcript level HPA011403, HPA042997, HPA044010, HPA046970 Approved Approved Nucleoplasm Mixed Expressed in all cerebral cortex: 58.6 POLR2K RPB10alpha ENSG00000147669 Polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 8 100150584-100154002 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA063185 Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all thyroid gland: 98.0 POLR2L hRPB7.6, hsRPB10b, RBP10, RPABC5, RPB10beta, RPB7.6 ENSG00000177700 Polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 11 837356-842545 Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level Liver cancer:2.37e-4 (unfavourable), Renal cancer:5.56e-4 (favourable) Expressed in all Expressed in all adipose tissue: 67.7 POLR2M GCOM1, Gdown, Gdown1, GRINL1A ENSG00000255529 Polymerase (RNA) II (DNA directed) polypeptide M 15 57706629-57782762 Predicted intracellular proteins Evidence at protein level HPA068141 Approved Nucleoplasm Expressed in all Expressed in all endometrium: 56.3 POLR3A hRPC155, RPC1, RPC155 ENSG00000148606 Polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 10 77969251-78029545 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA037926 Uncertain Supported Nucleoplasm Liver cancer:3.64e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 17.9 POLR3C RPC3, RPC62 ENSG00000186141 Polymerase (RNA) III (DNA directed) polypeptide C (62kD) 1 145824088-145842505 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA027508, HPA027516 Uncertain Validated Nucleoplasm Renal cancer:1.85e-5 (unfavourable), Melanoma:1.50e-4 (unfavourable), Endometrial cancer:1.56e-4 (unfavourable), Liver cancer:5.48e-4 (unfavourable) Expressed in all Expressed in all testis: 53.0 POLR3D BN51T, RPC4, TSBN51 ENSG00000168495 Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 8 22245104-22254600 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA061331, HPA067875, HPA068461, HPA069089 Supported Validated Nucleoplasm Renal cancer:9.15e-6 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Urothelial cancer:2.12e-4 (unfavourable) Expressed in all Expressed in all testis: 24.6 POLR3E FLJ10509, RPC5, SIN ENSG00000058600 Polymerase (RNA) III (DNA directed) polypeptide E (80kD) 16 22297375-22335103 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA041419, HPA041477 Approved Validated Nucleoplasm Prostate cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 17.5 POLR3GL flj32422, MGC3200 ENSG00000121851 Polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like 1 145964702-145978848 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA027288 Uncertain Approved Nucleoplasm
Golgi apparatus
Cytosol Endometrial cancer:6.52e-5 (favourable), Breast cancer:2.96e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 58.9 POLR3H KIAA1665, RPC8 ENSG00000100413 Polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 22 41525804-41544606 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA046787 Approved Supported Nucleoplasm
Vesicles
Centrosome Liver cancer:2.04e-4 (unfavourable), Pancreatic cancer:5.41e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 35.6 POLR3K RPC11 ENSG00000161980 Polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 16 46407-53628 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA005891 Approved Uncertain Nucleus
Cytosol Expressed in all Expressed in all lymph node: 20.8 POLRMT APOLMT, h-mtRPOL, MTRNAP, MTRPOL ENSG00000099821 Polymerase (RNA) mitochondrial (DNA directed) 19 617224-633604 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006366 Uncertain Supported Mitochondria Endometrial cancer:4.50e-4 (favourable) Expressed in all Expressed in all testis: 46.6 POM121 DKFZP586G1822, DKFZP586P2220, KIAA0618, POM121A ENSG00000196313 POM121 transmembrane nucleoporin 7 72879365-72951440 Predicted intracellular proteins, Transporters Evidence at protein level CAB003710, HPA043809, HPA049817 Approved Validated Nucleoplasm
Nuclear membrane Expressed in all Expressed in all cerebral cortex: 30.2 POM121C ENSG00000272391 POM121 transmembrane nucleoporin C 7 75416787-75486271 Predicted intracellular proteins Evidence at transcript level HPA043809, HPA049817 Approved Approved Nucleoplasm
Nuclear membrane Expressed in all Expressed in all thyroid gland: 27.8 POMGNT1 FLJ20277, LGMD2O, MEB, MGAT1.2 ENSG00000085998 Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1 46188682-46220305 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044518 Approved Liver cancer:3.52e-4 (unfavourable), Pancreatic cancer:4.27e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 121.6 POMGNT2 AGO61, C3orf39, FLJ14566, GTDC2 ENSG00000144647 Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 3 43079232-43106076 Disease related genes, Predicted secreted proteins Evidence at protein level HPA034870, HPA040989 Uncertain Renal cancer:4.00e-7 (favourable), Liver cancer:1.26e-5 (unfavourable), Colorectal cancer:8.13e-5 (favourable) Expressed in all Expressed in all endometrium: 35.6 POMP C13orf12, HSPC014, UMP1 ENSG00000132963 Proteasome maturation protein 13 28659104-28678925 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026995 Approved Supported Nuclear speckles Head and neck cancer:2.05e-5 (unfavourable) Expressed in all Expressed in all placenta: 143.9 POMT1 LGMD2K ENSG00000130714 Protein-O-mannosyltransferase 1 9 131502902-131523806 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA065252 Approved Golgi apparatus Pancreatic cancer:3.90e-5 (favourable), Renal cancer:4.68e-5 (favourable) Expressed in all Expressed in all testis: 62.7 POMT2 LGMD2N ENSG00000009830 Protein-O-mannosyltransferase 2 14 77274956-77320884 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA003663 Uncertain Liver cancer:2.40e-4 (unfavourable) Expressed in all Expressed in all testis: 28.8 PON2 ENSG00000105854 Paraoxonase 2 7 95404863-95435329 Candidate cardiovascular disease genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025430, HPA029193 Supported Renal cancer:4.30e-8 (unfavourable), Cervical cancer:1.43e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 226.9 POP4 RPP29 ENSG00000105171 POP4 homolog, ribonuclease P/MRP subunit 19 29604017-29617237 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042748 Approved Liver cancer:3.31e-4 (unfavourable) Expressed in all Expressed in all testis: 15.3 POP5 ENSG00000167272 POP5 homolog, ribonuclease P/MRP subunit 12 120578764-120581398 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047598, HPA069204 Approved Approved Nucleus
Nucleoli Cervical cancer:2.68e-5 (favourable), Renal cancer:4.85e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.8 POP7 RPP2, RPP20 ENSG00000172336 POP7 homolog, ribonuclease P/MRP subunit 7 100706053-100707495 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021007 Uncertain Supported Nucleoli
Vesicles Liver cancer:4.99e-5 (unfavourable), Renal cancer:6.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 41.2 POR CYPOR, FLJ26468 ENSG00000127948 P450 (cytochrome) oxidoreductase 7 75899200-75986855 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB004372, HPA010136 Supported Approved Nucleoplasm
Vesicles
Cytosol Glioma:5.23e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 219.8 PPA1 IOPPP, PP, PP1, Ppase, SID6-8061 ENSG00000180817 Pyrophosphatase (inorganic) 1 10 70202830-70233911 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019878, HPA020096 Supported Supported Vesicles Expressed in all Expressed in all breast: 225.4 PPA2 FLJ20459 ENSG00000138777 Pyrophosphatase (inorganic) 2 4 105369077-105474081 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030888, HPA031671, HPA031672 Supported Approved Nucleus
Mitochondria Renal cancer:1.27e-11 (favourable), Breast cancer:2.98e-4 (unfavourable), Colorectal cancer:6.60e-4 (favourable) Expressed in all Expressed in all kidney: 21.6 PPAN BXDC3, SSF, SSF1, SSF2 ENSG00000130810 Peter pan homolog (Drosophila) 19 10106289-10111634 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043265 Approved Expressed in all Expressed in all appendix: 20.7 PPARA hPPAR, NR1C1, PPAR ENSG00000186951 Peroxisome proliferator-activated receptor alpha 22 46150521-46243756 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058901, HPA067049 Supported Nucleus Renal cancer:4.39e-9 (favourable) Expressed in all Expressed in all kidney: 24.0 PPARD FAAR, NR1C2, NUC1, NUCII ENSG00000112033 Peroxisome proliferator-activated receptor delta 6 35342558-35428191 FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB017635 Approved Liver cancer:4.57e-4 (unfavourable) Expressed in all Expressed in all placenta: 40.1 PPCDC FLJ14585, MDS018 ENSG00000138621 Phosphopantothenoylcysteine decarboxylase 15 75023555-75117462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045667 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 21.9 PPCS FLJ11838 ENSG00000127125 Phosphopantothenoylcysteine synthetase 1 42456117-42473385 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031361, HPA031363 Approved Approved Nucleus
Nucleoli fibrillar center
Mitochondria Liver cancer:5.96e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 110.1 PPDPF C20orf149, dJ697K14.9, exdpf ENSG00000125534 Pancreatic progenitor cell differentiation and proliferation factor 20 63520724-63522206 Predicted intracellular proteins Evidence at protein level HPA040929 Approved Nucleoplasm
Nucleoli
Microtubules Renal cancer:3.91e-4 (favourable) Expressed in all Expressed in all stomach: 213.7 PPFIA1 LIP.1, LIPRIN ENSG00000131626 Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 11 70270700-70384403 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008272, CAB017032, HPA042271 Uncertain Validated Focal adhesion sites
Cytosol Renal cancer:3.76e-4 (favourable), Head and neck cancer:5.58e-4 (unfavourable), Pancreatic cancer:8.26e-4 (unfavourable) Expressed in all Expressed in all testis: 56.9 PPFIBP1 hSGT2, hSgt2p, L2, SGT2 ENSG00000110841 PTPRF interacting protein, binding protein 1 (liprin beta 1) 12 27523431-27695564 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001924 Uncertain Approved Plasma membrane
Cytosol Renal cancer:5.11e-7 (favourable), Pancreatic cancer:2.56e-4 (unfavourable), Lung cancer:5.11e-4 (unfavourable), Endometrial cancer:6.29e-4 (unfavourable) Expressed in all Expressed in all ovary: 106.2 PPFIBP2 Cclp1 ENSG00000166387 PTPRF interacting protein, binding protein 2 (liprin beta 2) 11 7513298-7657127 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001935, HPA003911 Approved Approved Mitochondria Renal cancer:5.39e-8 (favourable), Urothelial cancer:1.34e-5 (favourable), Lung cancer:2.26e-5 (favourable), Head and neck cancer:2.32e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 184.4 PPHLN1 ENSG00000134283 Periphilin 1 12 42238447-42459715 Predicted intracellular proteins Evidence at protein level HPA038902, HPA038903 Supported Validated Nucleoplasm
Golgi apparatus Liver cancer:1.28e-7 (unfavourable), Renal cancer:5.06e-5 (unfavourable) Expressed in all Expressed in all testis: 101.7 PPIA CYPA ENSG00000196262 Peptidylprolyl isomerase A (cyclophilin A) 7 44796680-44824564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004655, HPA058345 Uncertain Liver cancer:2.27e-6 (unfavourable) Expressed in all Expressed in all breast: 1666.2 PPIB CYPB, OI9 ENSG00000166794 Peptidylprolyl isomerase B (cyclophilin B) 15 64155812-64163205 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level CAB011487, HPA012720 Supported Supported Nucleus
Endoplasmic reticulum Renal cancer:2.02e-11 (unfavourable), Endometrial cancer:1.56e-5 (favourable) Expressed in all Expressed in all thyroid gland: 852.0 PPID CYP-40 ENSG00000171497 Peptidylprolyl isomerase D 4 158709134-158723396 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019520, HPA019692 Approved Supported Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all liver: 71.3 PPIE CyP-33, MGC111222, MGC3736 ENSG00000084072 Peptidylprolyl isomerase E (cyclophilin E) 1 39692182-39763914 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019357, HPA020131 Approved Supported Nuclear speckles Renal cancer:5.05e-5 (unfavourable), Liver cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 66.4 PPIF Cyp-D, hCyP3 ENSG00000108179 Peptidylprolyl isomerase F 10 79347469-79355337 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA077416 Supported Mitochondria Expressed in all Expressed in all adrenal gland: 189.4 PPIG CARS-Cyp, SCAF10, SRCyp ENSG00000138398 Peptidylprolyl isomerase G (cyclophilin G) 2 169584340-169641406 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021788, HPA057469 Supported Supported Nuclear speckles
Cytosol Renal cancer:4.56e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 85.0 PPIH CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP ENSG00000171960 Peptidylprolyl isomerase H (cyclophilin H) 1 42658425-42676758 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA059019 Approved Renal cancer:1.78e-9 (unfavourable), Liver cancer:1.55e-5 (unfavourable) Expressed in all Expressed in all testis: 67.6 PPIL1 CYPL1 ENSG00000137168 Peptidylprolyl isomerase (cyclophilin)-like 1 6 36854827-36875024 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA062916 Approved Nucleoli Liver cancer:1.28e-5 (unfavourable), Ovarian cancer:4.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.9 PPIL2 CYC4, Cyp-60, UBOX7 ENSG00000100023 Peptidylprolyl isomerase (cyclophilin)-like 2 22 21652270-21700015 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035344, HPA055637 Supported Validated Nucleoplasm Expressed in all Expressed in all thyroid gland: 31.5 PPIL3 CyPJ ENSG00000240344 Peptidylprolyl isomerase (cyclophilin)-like 3 2 200870907-200889303 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040765, HPA062187 Approved Supported Nucleus Ovarian cancer:1.19e-4 (favourable), Renal cancer:5.16e-4 (unfavourable) Expressed in all Expressed in all ovary: 45.4 PPIL4 ENSG00000131013 Peptidylprolyl isomerase (cyclophilin)-like 4 6 149504733-149546038 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031599, HPA031600 Approved Validated Nucleoplasm Expressed in all Expressed in all thyroid gland: 47.9 PPIP5K1 HISPPD2A, IPS1, KIAA0377, VIP1 ENSG00000168781 Diphosphoinositol pentakisphosphate kinase 1 15 43533462-43590253 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039380 Approved Supported Cytosol Renal cancer:7.14e-8 (favourable), Ovarian cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 52.1 PPIP5K2 CFAP160, HISPPD1, KIAA0433, VIP2 ENSG00000145725 Diphosphoinositol pentakisphosphate kinase 2 5 103120149-103212799 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037895, HPA038442 Approved Approved Vesicles Thyroid cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.6 PPM1A MGC9201, PP2CA, PP2Calpha ENSG00000100614 Protein phosphatase, Mg2+/Mn2+ dependent, 1A 14 60245752-60299087 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029209 Approved Supported Plasma membrane
Cytosol Renal cancer:1.57e-9 (favourable) Expressed in all Expressed in all testis: 99.7 PPM1B PP2CB, PP2CBETA, PPC2BETAX ENSG00000138032 Protein phosphatase, Mg2+/Mn2+ dependent, 1B 2 44167969-44244384 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016745 Approved Approved Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 80.9 PPM1F CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2 ENSG00000100034 Protein phosphatase, Mg2+/Mn2+ dependent, 1F 22 21919420-21952837 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030989, HPA030990 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:6.03e-5 (unfavourable) Expressed in all Expressed in all placenta: 39.4 PPM1G PP2CG, PP2Cgamma ENSG00000115241 Protein phosphatase, Mg2+/Mn2+ dependent, 1G 2 27381194-27409687 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035530, HPA035531 Supported Validated Nucleoplasm Liver cancer:3.14e-7 (unfavourable), Ovarian cancer:6.08e-5 (favourable) Expressed in all Expressed in all testis: 336.6 PPM1K BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm ENSG00000163644 Protein phosphatase, Mg2+/Mn2+ dependent, 1K 4 88257620-88284769 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020066, HPA020862, HPA023891 Approved Supported Mitochondria Expressed in all Expressed in all heart muscle: 60.5 PPM1M FLJ32332, PP2Ceta ENSG00000164088 Protein phosphatase, Mg2+/Mn2+ dependent, 1M 3 52245793-52250597 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036905, HPA062291 Uncertain Approved Nuclear bodies Renal cancer:1.61e-5 (unfavourable), Lung cancer:6.69e-4 (favourable), Cervical cancer:7.73e-4 (favourable) Expressed in all Expressed in all lung: 34.9 PPME1 PME-1 ENSG00000214517 Protein phosphatase methylesterase 1 11 74171099-74254703 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004541, HPA043900, HPA064396 Uncertain Supported Nucleus Liver cancer:4.45e-6 (unfavourable), Renal cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 153.8 PPOX PPO, VP ENSG00000143224 Protoporphyrinogen oxidase 1 161166410-161178013 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030123 Uncertain Approved Mitochondria
Cytosol Renal cancer:9.89e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 37.3 PPP1CA PP-1A, PP1A, PP1alpha, PPP1A ENSG00000172531 Protein phosphatase 1, catalytic subunit, alpha isozyme 11 67398183-67421183 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB004545, HPA046833 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Thyroid cancer:1.17e-4 (favourable) Expressed in all Expressed in all lymph node: 168.7 PPP1CB PP-1B, PP1B, PP1beta ENSG00000213639 Protein phosphatase 1, catalytic subunit, beta isozyme 2 28751640-28802940 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022558, HPA065425, CAB069426 Supported Supported Nucleus
Plasma membrane
Cytosol Liver cancer:6.52e-6 (unfavourable) Expressed in all Expressed in all esophagus: 274.9 PPP1CC PP1C, PP1gamma ENSG00000186298 Protein phosphatase 1, catalytic subunit, gamma isozyme 12 110719680-110742939 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022645 Uncertain Liver cancer:2.75e-6 (unfavourable), Cervical cancer:7.44e-4 (favourable) Expressed in all Expressed in all testis: 256.1 PPP1R12A M130, MBS, MYPT1 ENSG00000058272 Protein phosphatase 1, regulatory subunit 12A 12 79773563-79935460 Predicted intracellular proteins Evidence at protein level HPA041296, HPA071956 Validated Actin filaments
Cytosol Liver cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 120.1 PPP1R12B MGC131980, MGC87886, MYPT2, PP1bp55 ENSG00000077157 Protein phosphatase 1, regulatory subunit 12B 1 202348699-202592706 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024171, HPA024640 Supported Supported Plasma membrane
Actin filaments Expressed in all Expressed in all endometrium: 363.9 PPP1R12C DKFZP434D0412, LENG3, MBS85, p84, p85 ENSG00000125503 Protein phosphatase 1, regulatory subunit 12C 19 55090913-55117559 Predicted intracellular proteins Evidence at protein level HPA043532 Approved Pancreatic cancer:4.10e-5 (favourable) Expressed in all Expressed in all endometrium: 112.4 PPP1R14B PHI-1, PLCB3N, PNG, SOM172 ENSG00000173457 Protein phosphatase 1, regulatory (inhibitor) subunit 14B 11 64244480-64246941 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053882 Approved Liver cancer:1.75e-6 (unfavourable), Pancreatic cancer:6.77e-4 (unfavourable) Expressed in all Expressed in all skin: 87.4 PPP1R15A GADD34 ENSG00000087074 Protein phosphatase 1, regulatory subunit 15A 19 48872392-48876057 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB018395, HPA020240 Approved Uncertain Vesicles Liver cancer:1.95e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 358.8 PPP1R15B FLJ14744 ENSG00000158615 Protein phosphatase 1, regulatory subunit 15B 1 204403387-204411791 Predicted intracellular proteins Evidence at protein level HPA061088 Approved Golgi apparatus Renal cancer:8.74e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 81.7 PPP1R16A MGC14333, MYPT3 ENSG00000160972 Protein phosphatase 1, regulatory subunit 16A 8 144477969-144502121 Predicted intracellular proteins Evidence at protein level HPA023755 Uncertain Approved Plasma membrane Expressed in all Expressed in all duodenum: 27.9 PPP1R2 IPP2 ENSG00000184203 Protein phosphatase 1, regulatory (inhibitor) subunit 2 3 195514425-195543386 Predicted intracellular proteins Evidence at protein level HPA043729, HPA059420 Uncertain Validated Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 54.6 PPP1R21 CCDC128, FLJ16566, KLRAQ1 ENSG00000162869 Protein phosphatase 1, regulatory subunit 21 2 48440598-48515391 Predicted intracellular proteins Evidence at protein level HPA036791, HPA036792 Approved Approved Vesicles Renal cancer:4.59e-6 (favourable), Endometrial cancer:6.83e-4 (unfavourable), Pancreatic cancer:8.05e-4 (favourable), Thyroid cancer:9.87e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 61.0 PPP1R37 LRRC68 ENSG00000104866 Protein phosphatase 1, regulatory subunit 37 19 45091396-45148077 Predicted intracellular proteins Evidence at protein level HPA041500 Approved Approved Cytosol Urothelial cancer:2.04e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.4 PPP1R3B FLJ14005, GL, PPP1R4 ENSG00000173281 Protein phosphatase 1, regulatory subunit 3B 8 9136255-9151574 Predicted intracellular proteins Evidence at protein level HPA028731 Approved Approved Cytosol Renal cancer:4.08e-7 (unfavourable), Stomach cancer:6.03e-5 (unfavourable), Pancreatic cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 148.6 PPP1R7 sds22 ENSG00000115685 Protein phosphatase 1, regulatory subunit 7 2 241149576-241183652 Predicted intracellular proteins Evidence at protein level HPA034500, HPA034501 Approved Approved Nucleoli Expressed in all Expressed in all testis: 286.4 PPP1R8 ard-1, ARD1, NIPP-1, NIPP1, PRO2047 ENSG00000117751 Protein phosphatase 1, regulatory subunit 8 1 27830778-27851676 Predicted intracellular proteins Evidence at protein level HPA027406, HPA027417, HPA027452 Supported Validated Nucleoplasm
Nuclear speckles Liver cancer:2.19e-5 (unfavourable) Expressed in all Expressed in all endometrium: 46.5 PPP1R9B PPP1R6, PPP1R9, SPINO, Spn ENSG00000108819 Protein phosphatase 1, regulatory subunit 9B 17 50133735-50150630 Predicted intracellular proteins Evidence at protein level CAB022461 Approved Pancreatic cancer:3.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 76.5 PPP2CA PP2Calpha ENSG00000113575 Protein phosphatase 2, catalytic subunit, alpha isozyme 5 134194334-134226142 Enzymes, Predicted intracellular proteins Evidence at protein level CAB003848, HPA043236 Approved Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 127.0 PPP2CB PP2Abeta ENSG00000104695 Protein phosphatase 2, catalytic subunit, beta isozyme 8 30774457-30814314 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018600, HPA043236 Approved Supported Nucleoplasm Renal cancer:5.82e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 208.0 PPP2R1A PP2A-Aalpha, PR65A ENSG00000105568 Protein phosphatase 2, regulatory subunit A, alpha 19 52190039-52229533 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018599 Approved Cytosol Renal cancer:1.20e-4 (favourable), Liver cancer:1.76e-4 (unfavourable), Lung cancer:2.50e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 205.2 PPP2R1B PP2A-Abeta, PR65B ENSG00000137713 Protein phosphatase 2, regulatory subunit A, beta 11 111726908-111766427 Predicted intracellular proteins Evidence at protein level CAB004034, HPA018908 Approved Approved Nucleus
Plasma membrane
Centrosome
Cytosol Liver cancer:3.80e-4 (favourable) Expressed in all Expressed in all testis: 98.2 PPP2R2A B55A, PR52A, PR55A ENSG00000221914 Protein phosphatase 2, regulatory subunit B, alpha 8 26291491-26372680 Predicted intracellular proteins Evidence at protein level HPA042122, HPA042770, HPA059497 Approved Approved Cytosol Expressed in all Expressed in all placenta: 72.3 PPP2R3C C14orf10, FLJ20644, G4-1, G5PR ENSG00000092020 Protein phosphatase 2, regulatory subunit B'', gamma 14 35085467-35122517 Predicted intracellular proteins Evidence at protein level HPA040835, HPA058834 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all testis: 97.5 PPP2R4 PR53, PTPA ENSG00000119383 Protein phosphatase 2A activator, regulatory subunit 4 9 129110950-129148946 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005695, CAB022068, CAB035999 Approved Validated Nucleoplasm
Cytosol Endometrial cancer:6.50e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 221.8 PPP2R5A B56A, PR61A ENSG00000066027 Protein phosphatase 2, regulatory subunit B', alpha 1 212285537-212361863 Predicted intracellular proteins Evidence at protein level HPA059288 Supported Cytosol Expressed in all Expressed in all lung: 86.6 PPP2R5B B56B, FLJ35411, PR61B ENSG00000068971 Protein phosphatase 2, regulatory subunit B', beta 11 64917553-64934473 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036607 Approved Liver cancer:3.24e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 59.9 PPP2R5C B56G, PR61G ENSG00000078304 Protein phosphatase 2, regulatory subunit B', gamma 14 101761798-101927989 Predicted intracellular proteins Evidence at protein level HPA027553 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Expressed in all lymph node: 160.0 PPP2R5D B56D ENSG00000112640 Protein phosphatase 2, regulatory subunit B', delta 6 42984499-43012342 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029045, HPA029046 Approved Approved Nucleoplasm
Cytosol Liver cancer:3.89e-4 (unfavourable) Expressed in all Expressed in all testis: 43.2 PPP2R5E ENSG00000154001 Protein phosphatase 2, regulatory subunit B', epsilon isoform 14 63371357-63543374 Predicted intracellular proteins Evidence at protein level HPA006034 Approved Supported Cytosol Liver cancer:1.95e-4 (unfavourable), Renal cancer:4.16e-4 (favourable) Expressed in all Expressed in all thyroid gland: 33.7 PPP3CA CALN, CALNA, CNA1, PPP2B ENSG00000138814 Protein phosphatase 3, catalytic subunit, alpha isozyme 4 101023409-101348278 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012778, CAB018581 Supported Validated Nucleoplasm
Cytosol Pancreatic cancer:3.82e-4 (unfavourable) Tissue enriched Expressed in all cerebral cortex: 164.8 PPP3CB CALNA2, CALNB, CNA2, PP2Bbeta ENSG00000107758 Protein phosphatase 3, catalytic subunit, beta isozyme 10 73436428-73496024 Enzymes, Predicted intracellular proteins Evidence at protein level HPA008233, HPA008823 Uncertain Approved Mitochondria Pancreatic cancer:6.96e-5 (favourable), Liver cancer:9.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 153.6 PPP3CC CALNA3, PP2Bgamma ENSG00000120910 Protein phosphatase 3, catalytic subunit, gamma isozyme 8 22440819-22541142 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023396, CAB024950 Approved Approved Vesicles Lung cancer:6.80e-5 (favourable) Expressed in all Expressed in all testis: 101.2 PPP3R1 CALNB1, CNB, CNB1 ENSG00000221823 Protein phosphatase 3, regulatory subunit B, alpha 2 68178857-68256237 Predicted intracellular proteins Evidence at protein level CAB005610, HPA047157 Approved Approved Plasma membrane
Cytosol Endometrial cancer:9.08e-6 (unfavourable), Renal cancer:1.70e-5 (unfavourable), Liver cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 198.1 PPP4C PP4, PPX ENSG00000149923 Protein phosphatase 4, catalytic subunit 16 30075978-30085377 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043837 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 77.8 PPP4R1 PP4R1 ENSG00000154845 Protein phosphatase 4, regulatory subunit 1 18 9546791-9615240 Predicted intracellular proteins Evidence at protein level HPA040905, HPA041089 Uncertain Approved Nucleoplasm Expressed in all Expressed in all esophagus: 78.5 PPP4R2 ENSG00000163605 Protein phosphatase 4, regulatory subunit 2 3 72996785-73069199 Predicted intracellular proteins Evidence at protein level HPA034695, HPA039837, HPA073758 Supported Validated Nucleoplasm Expressed in all Expressed in all bone marrow: 66.8 PPP4R3A FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1 ENSG00000100796 Protein phosphatase 4, regulatory subunit 3A 14 91457611-91510554 Predicted intracellular proteins Evidence at protein level HPA002568, HPA063917 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 61.0 PPP4R3B FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2 ENSG00000275052 Protein phosphatase 4, regulatory subunit 3B 2 55547292-55618880 Predicted intracellular proteins Evidence at protein level HPA001233, CAB017185 Uncertain Supported Nucleoplasm
Nuclear speckles
Centrosome Renal cancer:6.03e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 57.8 PPP5C PP5, PPP5 ENSG00000011485 Protein phosphatase 5, catalytic subunit 19 46346994-46392981 Enzymes, Predicted intracellular proteins Evidence at protein level CAB022641, HPA029065, HPA056933 Approved Supported Vesicles
Cytosol Liver cancer:3.45e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 44.5 PPP6C PP6 ENSG00000119414 Protein phosphatase 6, catalytic subunit 9 125146573-125189939 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA050940 Uncertain Renal cancer:4.50e-6 (favourable) Expressed in all Expressed in all thyroid gland: 52.4 PPP6R1 KIAA1115, SAP190, SAPS1 ENSG00000105063 Protein phosphatase 6, regulatory subunit 1 19 55229780-55258995 Predicted intracellular proteins Evidence at protein level HPA043989, HPA063681 Approved Validated Cytosol Liver cancer:3.82e-6 (unfavourable) Expressed in all Expressed in all testis: 117.3 PPP6R2 dJ579N16.1, KIAA0685, SAP190, SAPS2 ENSG00000100239 Protein phosphatase 6, regulatory subunit 2 22 50343304-50445090 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030656, CAB034919 Uncertain Supported Vesicles
Cytosol Endometrial cancer:1.70e-5 (favourable), Pancreatic cancer:7.51e-4 (favourable) Expressed in all Expressed in all testis: 65.3 PPP6R3 C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3 ENSG00000110075 Protein phosphatase 6, regulatory subunit 3 11 68460731-68615334 Predicted intracellular proteins Evidence at protein level CAB017183, HPA038467, HPA038468 Supported Validated Nucleoplasm
Plasma membrane
Cytosol Testis cancer:8.23e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 92.1 PPRC1 KIAA0595, MGC74642, PRC ENSG00000148840 Peroxisome proliferator-activated receptor gamma, coactivator-related 1 10 102132994-102150331 Predicted intracellular proteins Evidence at protein level HPA038511, HPA057571 Approved Validated Nucleoplasm Renal cancer:6.71e-7 (unfavourable) Expressed in all Expressed in all skin: 20.7 PPT1 CLN1, INCL, PPT ENSG00000131238 Palmitoyl-protein thioesterase 1 1 40072705-40097703 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021546 Supported Liver cancer:6.98e-8 (unfavourable) Expressed in all Expressed in all spleen: 196.0 PPTC7 TA-PP2C ENSG00000196850 PTC7 protein phosphatase homolog 12 110533245-110583320 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039335, HPA040614 Approved Approved Plasma membrane
Cytosol Ovarian cancer:1.43e-5 (unfavourable), Renal cancer:4.48e-5 (favourable), Pancreatic cancer:6.76e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.7 PPWD1 KIAA0073 ENSG00000113593 Peptidylprolyl isomerase domain and WD repeat containing 1 5 65563236-65587549 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019353, HPA019360 Approved Supported Nuclear bodies Liver cancer:2.19e-4 (unfavourable), Renal cancer:6.72e-4 (unfavourable) Expressed in all Expressed in all lymph node: 32.0 PQBP1 MRX2, MRX55, MRXS8, RENS1, SHS ENSG00000102103 Polyglutamine binding protein 1 X 48897912-48903143 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001880 Supported Validated Nuclear speckles Renal cancer:2.68e-7 (unfavourable), Cervical cancer:1.48e-4 (favourable) Expressed in all Expressed in all ovary: 49.9 PQLC1 FLJ22378 ENSG00000122490 PQ loop repeat containing 1 18 79902420-79951664 Predicted membrane proteins Evidence at protein level HPA051666 Uncertain Approved Nucleoplasm Expressed in all Expressed in all adipose tissue: 40.5 PQLC2 FLJ20320 ENSG00000040487 PQ loop repeat containing 2 1 19312326-19329300 Predicted membrane proteins, Transporters Evidence at protein level HPA057810 Approved Validated Vesicles Liver cancer:2.64e-5 (unfavourable), Endometrial cancer:3.50e-4 (favourable) Expressed in all Expressed in all testis: 16.3 PQLC3 C2orf22, MGC33602 ENSG00000162976 PQ loop repeat containing 3 2 11155198-11178874 Predicted membrane proteins Evidence at protein level HPA061607 Approved Cytosol Expressed in all Expressed in all cervix, uterine: 54.2 PRADC1 C2orf7, hPAP21, MGC13004, PAP21 ENSG00000135617 Protease-associated domain containing 1 2 73228006-73233238 Predicted secreted proteins Evidence at protein level HPA051066 Approved Expressed in all Expressed in all heart muscle: 43.9 PRAF2 JM4 ENSG00000243279 PRA1 domain family, member 2 X 49071156-49074071 Predicted membrane proteins Evidence at protein level HPA002859, HPA005504, CAB011655 Supported Approved Endoplasmic reticulum
Vesicles Liver cancer:1.66e-6 (unfavourable), Pancreatic cancer:4.88e-6 (favourable), Renal cancer:5.83e-6 (unfavourable), Lung cancer:2.81e-4 (favourable), Cervical cancer:7.42e-4 (favourable) Expressed in all Expressed in all epididymis: 181.8 PRC1 ASE1 ENSG00000198901 Protein regulator of cytokinesis 1 15 90966038-90995629 Predicted intracellular proteins Evidence at protein level HPA034521 Supported Approved Nucleoplasm
Plasma membrane
Microtubules Renal cancer:0.00e+0 (unfavourable), Pancreatic cancer:2.76e-5 (unfavourable), Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all testis: 99.7 PRCC RCCP1 ENSG00000143294 Papillary renal cell carcinoma (translocation-associated) 1 156750610-156800817 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017151, HPA019463, HPA019481 Supported Validated Nuclear speckles Renal cancer:8.99e-15 (unfavourable), Thyroid cancer:3.72e-4 (unfavourable), Endometrial cancer:5.55e-4 (unfavourable), Liver cancer:8.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 54.7 PRCP HUMPCP, PCP ENSG00000137509 Prolylcarboxypeptidase (angiotensinase C) 11 82823502-82970584 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017065 Approved Renal cancer:2.65e-6 (favourable) Expressed in all Expressed in all placenta: 220.6 PRDM2 HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2 ENSG00000116731 PR domain containing 2, with ZNF domain 1 13700198-13825079 Enzymes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005809 Approved Approved Nucleus
Golgi apparatus Expressed in all Expressed in all bone marrow: 51.3 PRDM4 PFM1 ENSG00000110851 PR domain containing 4 12 107732866-107761272 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024322, HPA067437 Approved Supported Nucleoplasm Renal cancer:3.15e-7 (favourable), Liver cancer:1.86e-4 (unfavourable), Melanoma:7.66e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 88.4 PRDX1 NKEFA, PAGA ENSG00000117450 Peroxiredoxin 1 1 45511036-45523047 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004682, HPA007730 Approved Supported Mitochondria Liver cancer:1.17e-5 (unfavourable), Urothelial cancer:2.89e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 1203.6 PRDX2 MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA ENSG00000167815 Peroxiredoxin 2 19 12796820-12801859 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008713 Approved Renal cancer:5.66e-11 (favourable) Expressed in all Expressed in all adrenal gland: 471.1 PRDX3 AOP-1, AOP1, MER5, SP-22 ENSG00000165672 Peroxiredoxin 3 10 119167703-119178833 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008656, HPA041488 Supported Expressed in all Expressed in all adrenal gland: 431.2 PRDX4 AOE37-2 ENSG00000123131 Peroxiredoxin 4 X 23664262-23686399 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB008659, CAB027389, CAB047362 Supported Supported Endoplasmic reticulum
Cytosol Renal cancer:1.33e-6 (unfavourable) Expressed in all Expressed in all pancreas: 239.4 PRDX5 ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10 ENSG00000126432 Peroxiredoxin 5 11 64318088-64321811 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008661, HPA037915, HPA037916 Supported Validated Mitochondria
Cytosol Renal cancer:1.24e-5 (favourable) Expressed in all Expressed in all fallopian tube: 599.3 PRDX6 1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX ENSG00000117592 Peroxiredoxin 6 1 173477266-173488807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006983, CAB008663 Supported Supported Plasma membrane
Cytosol Head and neck cancer:1.23e-5 (unfavourable), Renal cancer:9.51e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 363.4 PREB SEC12 ENSG00000138073 Prolactin regulatory element binding 2 27130756-27134675 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013582, HPA014133 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all epididymis: 106.0 PRELID1 CGI-106, PRELI, PX19 ENSG00000169230 PRELI domain containing 1 5 177303774-177306959 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005701 Approved Supported Nucleoplasm
Mitochondria Renal cancer:2.89e-7 (unfavourable), Liver cancer:5.46e-5 (unfavourable) Expressed in all Expressed in all small intestine: 133.0 PRELID3B C20orf45, dJ543J19.5, SLMO2 ENSG00000101166 PRELI domain containing 3B 20 59033145-59042909 Predicted intracellular proteins Evidence at protein level HPA047721 Uncertain Approved Nucleus Liver cancer:6.96e-5 (unfavourable), Endometrial cancer:5.04e-4 (unfavourable) Expressed in all Expressed in all duodenum: 90.4 PREP ENSG00000085377 Prolyl endopeptidase 6 105277565-105403084 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025414, HPA031388, HPA031389, HPA031390 Supported Validated Cytosol Head and neck cancer:3.33e-4 (unfavourable) Expressed in all Expressed in all rectum: 54.6 PREPL KIAA0436 ENSG00000138078 Prolyl endopeptidase-like 2 44316281-44361862 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA063238 Approved Expressed in all Expressed in all cerebral cortex: 258.1 PREX1 KIAA1415, P-REX1 ENSG00000124126 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 20 48624252-48827883 Predicted intracellular proteins Evidence at protein level HPA001927 Supported Supported Vesicles
Cytosol Head and neck cancer:8.56e-4 (favourable) Expressed in all Expressed in all spleen: 61.8 PRIM1 ENSG00000198056 Primase, DNA, polypeptide 1 (49kDa) 12 56731596-56752373 Predicted intracellular proteins Evidence at protein level HPA040010 Uncertain Supported Vesicles Liver cancer:2.40e-8 (unfavourable) Expressed in all Expressed in all testis: 21.7 PRKAA1 AMPKa1 ENSG00000132356 Protein kinase, AMP-activated, alpha 1 catalytic subunit 5 40759379-40798374 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB005050, HPA035409, HPA064946 Supported Supported Nuclear speckles Expressed in all Expressed in all testis: 74.4 PRKAB1 ENSG00000111725 Protein kinase, AMP-activated, beta 1 non-catalytic subunit 12 119667753-119681630 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA004247, CAB005058 Supported Approved Nucleoplasm
Cytosol Renal cancer:5.40e-9 (favourable), Endometrial cancer:8.66e-4 (favourable) Expressed in all Expressed in all kidney: 53.7 PRKAB2 ENSG00000131791 Protein kinase, AMP-activated, beta 2 non-catalytic subunit 1 147155106-147172550 Predicted intracellular proteins Evidence at protein level HPA044342 Approved Approved Nucleoplasm Thyroid cancer:6.78e-7 (unfavourable), Breast cancer:4.55e-4 (unfavourable), Head and neck cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.8 PRKACA PKACa ENSG00000072062 Protein kinase, cAMP-dependent, catalytic, alpha 19 14091688-14118084 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010361, HPA071185 Approved Approved Cytosol Cervical cancer:6.28e-6 (favourable), Endometrial cancer:6.26e-5 (unfavourable), Pancreatic cancer:6.47e-4 (favourable) Expressed in all Expressed in all heart muscle: 203.1 PRKAG1 ENSG00000181929 Protein kinase, AMP-activated, gamma 1 non-catalytic subunit 12 49002274-49019197 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA077805 Approved Nucleoplasm
Cytosol Liver cancer:2.84e-7 (unfavourable), Renal cancer:1.83e-4 (favourable) Expressed in all Expressed in all breast: 57.0 PRKAG2 AAKG, AAKG2, CMH6, H91620p, WPWS ENSG00000106617 Protein kinase, AMP-activated, gamma 2 non-catalytic subunit 7 151556111-151877125 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004246, CAB018641 Uncertain Approved Nucleoplasm Expressed in all Expressed in all heart muscle: 94.9 PRKAR1A CNC1, PRKAR1, TSE1 ENSG00000108946 Protein kinase, cAMP-dependent, regulatory, type I, alpha 17 68511780-68551319 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB019378, HPA049979 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 555.0 PRKAR2A PRKAR2 ENSG00000114302 Protein kinase, cAMP-dependent, regulatory, type II, alpha 3 48744597-48847846 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005023, HPA038268 Uncertain Supported Golgi apparatus
Vesicles
Microtubule organizing center Colorectal cancer:4.27e-5 (favourable), Liver cancer:1.97e-4 (unfavourable), Renal cancer:2.07e-4 (favourable) Expressed in all Expressed in all testis: 123.7 PRKCH PKC-L, PKCL, PRKCL ENSG00000027075 Protein kinase C, eta 14 61187559-61550976 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA026294, HPA053709 Approved Approved Plasma membrane
Cytosol Head and neck cancer:8.55e-6 (favourable) Expressed in all Expressed in all lymph node: 62.3 PRKCI DXS1179E, PKCI ENSG00000163558 Protein kinase C, iota 3 170222365-170305981 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA026574, HPA038635 Approved Validated Microtubules
Cytokinetic bridge
Cytosol Endometrial cancer:3.93e-6 (unfavourable), Pancreatic cancer:1.22e-4 (unfavourable), Liver cancer:3.02e-4 (unfavourable), Renal cancer:3.10e-4 (favourable) Expressed in all Expressed in all thyroid gland: 39.6 PRKCSH G19P1, PCLD, PLD1 ENSG00000130175 Protein kinase C substrate 80K-H 19 11435288-11450968 Disease related genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB004465, HPA041940, HPA043560 Supported Validated Endoplasmic reticulum Renal cancer:7.69e-4 (unfavourable) Expressed in all Expressed in all ovary: 236.9 PRKD2 DKFZP586E0820, HSPC187, PKD2 ENSG00000105287 Protein kinase D2 19 46674275-46717127 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021490, HPA056727 Supported Supported Nucleoplasm
Cytosol Urothelial cancer:9.15e-4 (favourable) Expressed in all Expressed in all spleen: 61.4 PRKD3 EPK2, PRKCN ENSG00000115825 Protein kinase D3 2 37250502-37324808 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029529 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:3.47e-4 (unfavourable), Colorectal cancer:4.84e-4 (favourable) Expressed in all Expressed in all testis: 44.2 PRKDC DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7 ENSG00000253729 Protein kinase, DNA-activated, catalytic polypeptide 8 47773108-47960183 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB005167, HPA035174 Supported Validated Nucleoplasm Endometrial cancer:1.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.0 PRKRA DYT16, HSD14, PACT, RAX ENSG00000180228 Protein kinase, interferon-inducible double stranded RNA dependent activator 2 178431414-178451512 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004648, HPA034996, HPA034997 Approved Supported Nucleoplasm
Cytosol Liver cancer:8.33e-5 (unfavourable), Testis cancer:5.45e-4 (favourable) Expressed in all Expressed in all testis: 56.2 PRKRIP1 C114, FLJ13902, KRBOX3 ENSG00000128563 PRKR interacting protein 1 (IL11 inducible) 7 102363872-102426676 Predicted intracellular proteins Evidence at protein level HPA051146 Uncertain Supported Actin filaments
Cytosol Urothelial cancer:1.94e-4 (favourable), Colorectal cancer:3.65e-4 (unfavourable), Renal cancer:4.39e-4 (unfavourable) Expressed in all Expressed in all testis: 34.7 PRKRIR DAP4, P52rIPK, THAP12 ENSG00000137492 Protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 11 76349956-76380971 Plasma proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA008758 Approved Approved Nucleoplasm Expressed in all Expressed in all endometrium: 42.6 PRMT1 ANM1, HCP1, HRMT1L2 ENSG00000126457 Protein arginine methyltransferase 1 19 49675786-49689029 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022550, HPA069769, HPA072136 Supported Supported Nucleoplasm Liver cancer:8.04e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 178.9 PRMT2 HRMT1L1, MGC111373 ENSG00000160310 Protein arginine methyltransferase 2 21 46635167-46665124 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018976, HPA029591 Uncertain Validated Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 98.0 PRMT3 HRMT1L3 ENSG00000185238 Protein arginine methyltransferase 3 11 20387530-20509294 Predicted intracellular proteins Evidence at protein level HPA007832, CAB022083 Uncertain Liver cancer:2.81e-5 (unfavourable), Pancreatic cancer:3.17e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 27.4 PRMT5 HRMT1L5, SKB1, SKB1Hs ENSG00000100462 Protein arginine methyltransferase 5 14 22920511-22929585 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005525, CAB012459, HPA064708 Approved Approved Nucleus
Cytosol Liver cancer:4.77e-5 (unfavourable), Urothelial cancer:1.04e-4 (unfavourable), Head and neck cancer:1.82e-4 (unfavourable), Pancreatic cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 71.4 PRMT7 FLJ10640, KIAA1933 ENSG00000132600 Protein arginine methyltransferase 7 16 68310974-68358563 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044241 Supported Supported Nucleoplasm
Nucleoli fibrillar center Endometrial cancer:2.31e-5 (favourable) Expressed in all Expressed in all fallopian tube: 24.8 PRNP AltPrP, CD230, CJD, GSS, PRIP, PRP ENSG00000171867 Prion protein 20 4686236-4701590 CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA042754, HPA043398 Supported Approved Nuclear membrane
Vesicles
Cytosol Liver cancer:7.41e-5 (unfavourable), Glioma:1.99e-4 (unfavourable), Colorectal cancer:2.96e-4 (unfavourable), Endometrial cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 621.3 PROCR CCD41, CD201, EPCR ENSG00000101000 Protein C receptor, endothelial 20 35172073-35216240 Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039461 Supported Renal cancer:7.62e-6 (unfavourable) Expressed in all Expressed in all adipose tissue: 62.7 PROSC ENSG00000147471 Proline synthetase co-transcribed homolog (bacterial) 8 37762593-37779767 Predicted intracellular proteins Evidence at protein level CAB017033, HPA023646, HPA023733 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 58.4 PROSER1 bA50D16.2, C13orf23, FLJ12661 ENSG00000120685 Proline and serine rich 1 13 39009866-39038076 Predicted intracellular proteins Evidence at protein level CAB034225, HPA055687 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all placenta: 30.0 PRPF18 hPrp18 ENSG00000165630 Pre-mRNA processing factor 18 10 13586927-13630868 Predicted intracellular proteins Evidence at protein level HPA037599, HPA047950 Supported Approved Nuclear speckles
Cytosol Liver cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 38.3 PRPF19 hPSO4, NMP200, PRP19, PSO4, UBOX4 ENSG00000110107 Pre-mRNA processing factor 19 11 60890730-60906588 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012448, HPA038051, HPA059070 Supported Validated Nuclear speckles Liver cancer:4.11e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 129.3 PRPF3 hPrp3, Prp3, RP18, SNRNP90 ENSG00000117360 Pre-mRNA processing factor 3 1 150321476-150353195 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027226, HPA067116 Approved Validated Nucleoplasm Renal cancer:3.19e-5 (unfavourable), Liver cancer:6.59e-5 (unfavourable) Expressed in all Expressed in all endometrium: 40.4 PRPF31 hPrp31, NY-BR-99, PRP31, RP11, SNRNP61 ENSG00000105618 Pre-mRNA processing factor 31 19 54115410-54131719 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041939, HPA061873 Supported Supported Nucleus Liver cancer:7.33e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.9 PRPF38A FLJ14936, Prp38 ENSG00000134748 Pre-mRNA processing factor 38A 1 52404564-52420839 Predicted intracellular proteins Evidence at protein level HPA053099, HPA058407 Uncertain Validated Nucleus Liver cancer:3.83e-5 (unfavourable), Renal cancer:7.41e-5 (unfavourable), Colorectal cancer:7.16e-4 (favourable) Expressed in all Expressed in all endometrium: 23.0 PRPF38B FLJ10330, NET1 ENSG00000134186 Pre-mRNA processing factor 38B 1 108692323-108701803 Predicted intracellular proteins Evidence at protein level HPA053255 Approved Renal cancer:2.03e-4 (unfavourable), Liver cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all lymph node: 52.4 PRPF4 HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60 ENSG00000136875 Pre-mRNA processing factor 4 9 113275343-113292905 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021794, HPA022248 Supported Validated Nuclear speckles Liver cancer:9.35e-4 (unfavourable) Expressed in all Expressed in all epididymis: 24.0 PRPF40A FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40 ENSG00000196504 PRP40 pre-mRNA processing factor 40 homolog A 2 152651593-152717997 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038272, HPA038273 Approved Validated Nuclear speckles Pancreatic cancer:1.58e-5 (unfavourable), Liver cancer:1.68e-4 (unfavourable), Renal cancer:5.89e-4 (unfavourable) Expressed in all Expressed in all testis: 49.9 PRPF4B KIAA0536, PR4H, Prp4 ENSG00000112739 Pre-mRNA processing factor 4B 6 4021267-4064983 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020638 Approved Supported Nuclear speckles Urothelial cancer:6.82e-5 (favourable), Liver cancer:2.27e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 37.5 PRPF6 ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K ENSG00000101161 Pre-mRNA processing factor 6 20 63981135-64033100 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047106 Supported Validated Nuclear speckles Expressed in all Expressed in all fallopian tube: 79.5 PRPF8 hPrp8, Prp8, PRPC8, RP13, SNRNP220 ENSG00000174231 Pre-mRNA processing factor 8 17 1650629-1684882 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009941, CAB015457 Supported Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 92.7 PRPS1 CMTX5, DFN2, DFNX1 ENSG00000147224 Phosphoribosyl pyrophosphate synthetase 1 X 107628424-107651026 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA043760 Uncertain Approved Cytosol Expressed in all Expressed in all thyroid gland: 73.6 PRPSAP1 PAP39 ENSG00000161542 Phosphoribosyl pyrophosphate synthetase-associated protein 1 17 76309486-76384521 Predicted intracellular proteins Evidence at protein level HPA062396 Approved Cytosol Colorectal cancer:1.39e-5 (favourable) Expressed in all Expressed in all thyroid gland: 82.1 PRPSAP2 PAP41 ENSG00000141127 Phosphoribosyl pyrophosphate synthetase-associated protein 2 17 18840085-18931287 Predicted intracellular proteins Evidence at protein level HPA021881 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:3.71e-4 (favourable) Expressed in all Expressed in all lymph node: 62.0 PRR13 DKFZP564J157, FLJ23818 ENSG00000205352 Proline rich 13 12 53441605-53446645 Predicted intracellular proteins Evidence at protein level HPA039396, HPA046219 Uncertain Validated Nucleoplasm Urothelial cancer:7.55e-4 (favourable), Cervical cancer:9.08e-4 (favourable) Expressed in all Expressed in all small intestine: 525.8 PRR14 MGC3121 ENSG00000156858 Proline rich 14 16 30650717-30656440 Predicted intracellular proteins Evidence at protein level HPA052022, HPA060265 Uncertain Approved Nucleoplasm Cervical cancer:8.19e-5 (favourable) Expressed in all Expressed in all spleen: 20.3 PRRC1 FLJ32875 ENSG00000164244 Proline-rich coiled-coil 1 5 127517609-127555089 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039212 Approved Approved Vesicles Breast cancer:9.35e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 53.1 PRRC2B BAT2L, BAT2L1, KIAA0515, LQFBS-1, MGC10526 ENSG00000130723 Proline-rich coiled-coil 2B 9 131394093-131500197 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021022, HPA064301 Uncertain Approved Nuclear bodies
Cytosol Renal cancer:5.42e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 133.4 PRRC2C BAT2D1, BAT2L2, KIAA1096, XTP2 ENSG00000117523 Proline-rich coiled-coil 2C 1 171485551-171593511 Predicted intracellular proteins Evidence at protein level HPA025766, HPA028659 Approved Validated Cytosol Renal cancer:7.76e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.3 PRSS23 SIG13, SPUVE ENSG00000150687 Protease, serine, 23 11 86791059-86952910 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030591 Uncertain Head and neck cancer:2.12e-4 (unfavourable), Renal cancer:3.06e-4 (unfavourable), Pancreatic cancer:5.56e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 394.9 PRUNE DRES-17, HTCD37 ENSG00000143363 Prune exopolyphosphatase 1 151008420-151035713 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028411 Uncertain Supported Cytosol Renal cancer:3.48e-4 (unfavourable), Endometrial cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 53.7 PSAP GLBA, SAP1 ENSG00000197746 Prosaposin 10 71816298-71851375 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA004426, CAB004647 Supported Supported Vesicles Expressed in all Expressed in all cerebral cortex: 1917.1 PSEN1 AD3, FAD, PS1, S182 ENSG00000080815 Presenilin 1 14 73136418-73223691 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB006844, HPA030760, HPA067496 Approved Approved Nucleus
Golgi apparatus
Cell Junctions Renal cancer:1.52e-8 (favourable), Liver cancer:1.99e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 66.1 PSEN2 AD3L, AD4, PS2, STM2 ENSG00000143801 Presenilin 2 1 226870184-226896105 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB013634, HPA038005 Supported Nucleus Expressed in all Expressed in all parathyroid gland: 29.1 PSENEN PEN2 ENSG00000205155 Presenilin enhancer gamma secretase subunit 19 35745114-35747519 Disease related genes, Predicted membrane proteins Evidence at protein level HPA047435 Approved Renal cancer:8.70e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 369.9 PSIP1 LEDGF, p52, p75, PSIP2 ENSG00000164985 PC4 and SFRS1 interacting protein 1 9 15464066-15511019 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013718, HPA019697 Supported Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 161.8 PSKH1 ENSG00000159792 Protein serine kinase H1 16 67893272-67929678 Enzymes, Predicted membrane proteins Evidence at protein level HPA053927 Approved Approved Nucleoplasm Renal cancer:4.28e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 48.6 PSMA1 HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30 ENSG00000129084 Proteasome subunit alpha 1 11 14504874-14643635 Enzymes, Predicted intracellular proteins Evidence at protein level CAB033765, HPA037646, HPA043891 Supported Validated Nucleoplasm Renal cancer:4.03e-11 (unfavourable), Liver cancer:3.79e-5 (unfavourable) Expressed in all Expressed in all placenta: 120.0 PSMA2 HC3, MU, PMSA2 ENSG00000106588 Proteasome subunit alpha 2 7 42916857-42932223 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008188 Uncertain Ovarian cancer:6.73e-5 (favourable), Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all liver: 164.2 PSMA3 HC8 ENSG00000100567 Proteasome subunit alpha 3 14 58244831-58272012 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000905 Approved Thyroid cancer:2.91e-4 (favourable) Expressed in all Expressed in all epididymis: 149.3 PSMA4 HC9, HsT17706 ENSG00000041357 Proteasome subunit alpha 4 15 78540405-78552419 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004973, HPA055466, HPA060613 Supported Validated Nucleus
Vesicles
Cytosol Renal cancer:6.74e-10 (unfavourable) Expressed in all Expressed in all testis: 173.1 PSMA6 IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27 ENSG00000100902 Proteasome subunit alpha 6 14 35278633-35317493 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003049 Approved Supported Nucleoplasm
Cytosol Ovarian cancer:3.27e-4 (favourable) Expressed in all Expressed in all testis: 387.7 PSMA7 C6, HSPC, RC6-1, XAPC7 ENSG00000101182 Proteasome subunit alpha 7 20 62136735-62143440 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047266 Uncertain Liver cancer:2.54e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 207.7 PSMB1 HC5, PMSB1 ENSG00000008018 Proteasome subunit beta 1 6 170535117-170553341 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029635, HPA029637, CAB033911 Supported Supported Nucleus Renal cancer:3.76e-6 (unfavourable) Expressed in all Expressed in all epididymis: 314.7 PSMB10 beta2i, LMP10, MECL1, MGC1665 ENSG00000205220 Proteasome subunit beta 10 16 67934502-67937087 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030224, HPA030225, CAB034384 Supported Supported Vesicles
Cytosol Urothelial cancer:5.44e-4 (favourable) Expressed in all Expressed in all lymph node: 92.6 PSMB2 HC7-I ENSG00000126067 Proteasome subunit beta 2 1 35599544-35641844 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026322, HPA026324 Approved Validated Nucleoplasm Liver cancer:3.49e-7 (unfavourable), Renal cancer:2.80e-6 (unfavourable) Expressed in all Expressed in all placenta: 43.0 PSMB3 HC10-II, MGC4147 ENSG00000277791 Proteasome subunit beta 3 17 38752736-38764231 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042775, HPA048147 Supported Renal cancer:1.71e-6 (unfavourable) Expressed in all Expressed in all epididymis: 82.2 PSMB4 HN3, PROS26 ENSG00000159377 Proteasome subunit beta 4 1 151399534-151401944 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006700 Approved Renal cancer:2.90e-10 (unfavourable), Liver cancer:7.45e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 272.2 PSMB5 MB1, X ENSG00000100804 Proteasome subunit beta 5 14 23016543-23035230 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049518, HPA061796 Approved Supported Nucleus
Centrosome Liver cancer:2.90e-5 (unfavourable), Ovarian cancer:1.08e-4 (favourable), Head and neck cancer:2.85e-4 (unfavourable), Urothelial cancer:4.73e-4 (unfavourable) Expressed in all Expressed in all epididymis: 139.6 PSMB6 DELTA, Y ENSG00000142507 Proteasome subunit beta 6 17 4796144-4798503 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023312, HPA063656 Supported Supported Nucleoplasm
Cytosol Renal cancer:5.93e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 196.1 PSMB7 ENSG00000136930 Proteasome subunit beta 7 9 124353466-124415444 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA052408, HPA054902 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 236.6 PSMC1 p56, S4 ENSG00000100764 Proteasome 26S subunit, ATPase 1 14 90256495-90275429 Predicted intracellular proteins Evidence at protein level HPA000872 Approved Validated Nucleoplasm
Cytosol Head and neck cancer:1.78e-4 (unfavourable) Expressed in all Expressed in all testis: 139.5 PSMC2 MSS1, Nbla10058, S7 ENSG00000161057 Proteasome 26S subunit, ATPase 2 7 103344254-103369395 Predicted intracellular proteins Evidence at protein level HPA019238, HPA049621 Approved Supported Cytosol
Cytoplasmic bodies Expressed in all Expressed in all thyroid gland: 72.0 PSMC3 TBP-1, TBP1 ENSG00000165916 Proteasome 26S subunit, ATPase 3 11 47418769-47426473 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006065 Approved Supported Nucleus
Cytosol Renal cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 117.3 PSMC4 MGC13687, MGC23214, MGC8570, MIP224, S6, TBP-7, TBP7 ENSG00000013275 Proteasome 26S subunit, ATPase 4 19 39971005-39981441 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002044, HPA005471 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland,thyroid gland: 42.3 PSMC5 p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1 ENSG00000087191 Proteasome 26S subunit, ATPase 5 17 63827152-63832026 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017871, HPA064293 Uncertain Supported Plasma membrane
Cytosol Renal cancer:3.13e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 245.8 PSMC6 p42 ENSG00000100519 Proteasome 26S subunit, ATPase 6 14 52707172-52728587 Predicted intracellular proteins Evidence at protein level HPA042823 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 91.4 PSMD1 P112, Rpn2, S1 ENSG00000173692 Proteasome 26S subunit, non-ATPase 1 2 231056864-231172827 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB021092, HPA036736, HPA036737 Approved Approved Nucleoplasm
Actin filaments Liver cancer:8.63e-12 (unfavourable), Lung cancer:2.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 200.6 PSMD10 p28 ENSG00000101843 Proteasome 26S subunit, non-ATPase 10 X 108084207-108091618 Predicted intracellular proteins Evidence at protein level HPA002920, CAB010434 Approved Supported Intermediate filaments
Cytosol Expressed in all Expressed in all cerebral cortex: 70.2 PSMD11 MGC3844, p44.5, Rpn6, S9 ENSG00000108671 Proteasome 26S subunit, non-ATPase 11 17 32444261-32483318 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042275, HPA067433 Approved Approved Nucleus
Golgi apparatus Renal cancer:5.73e-6 (unfavourable), Liver cancer:6.33e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 61.7 PSMD12 p55, Rpn5 ENSG00000197170 Proteasome 26S subunit, non-ATPase 12 17 67337916-67366627 Predicted intracellular proteins Evidence at protein level HPA023119 Approved Approved Nucleus
Microtubules
Cytosol Renal cancer:4.73e-6 (unfavourable), Liver cancer:1.21e-4 (unfavourable), Colorectal cancer:4.39e-4 (favourable), Ovarian cancer:6.32e-4 (favourable) Expressed in all Expressed in all testis: 26.1 PSMD13 p40.5, Rpn9 ENSG00000185627 Proteasome 26S subunit, non-ATPase 13 11 236546-252984 Predicted intracellular proteins Evidence at protein level HPA038691, HPA038692 Approved Approved Nuclear speckles
Cytosol Renal cancer:1.52e-13 (unfavourable), Liver cancer:4.76e-5 (unfavourable), Endometrial cancer:5.74e-4 (favourable) Expressed in all Expressed in all thyroid gland: 41.6 PSMD14 pad1, POH1, Rpn11 ENSG00000115233 Proteasome 26S subunit, non-ATPase 14 2 161308038-161411717 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002114, HPA003828 Approved Supported Nucleoplasm Liver cancer:2.66e-8 (unfavourable), Renal cancer:3.10e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 56.3 PSMD2 MGC14274, P97, Rpn1, S2, TRAP2 ENSG00000175166 Proteasome 26S subunit, non-ATPase 2 3 184298709-184309054 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045192 Approved Liver cancer:6.63e-7 (unfavourable), Lung cancer:1.55e-4 (unfavourable), Head and neck cancer:9.98e-4 (unfavourable) Expressed in all Expressed in all testis: 163.1 PSMD3 P58, Rpn3, S3, TSTA2 ENSG00000108344 Proteasome 26S subunit, non-ATPase 3 17 39980797-39997960 Predicted intracellular proteins Evidence at protein level CAB017038, HPA048972 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.47e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 83.8 PSMD4 AF, AF-1, Rpn10, S5A ENSG00000159352 Proteasome 26S subunit, non-ATPase 4 1 151254703-151267479 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA038807, HPA039252, CAB047300 Supported Validated Nucleoplasm
Cytosol Renal cancer:6.66e-10 (unfavourable) Expressed in all Expressed in all testis: 173.5 PSMD5 KIAA0072, S5B ENSG00000095261 Proteasome 26S subunit, non-ATPase 5 9 120815496-120842984 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003216 Uncertain Approved Nucleus
Cytosol Expressed in all Expressed in all breast: 28.7 PSMD6 KIAA0107, p44S10, Rpn7, S10 ENSG00000163636 Proteasome 26S subunit, non-ATPase 6 3 64010549-64024010 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036921, HPA036922 Uncertain Supported Golgi apparatus
Vesicles Liver cancer:1.68e-4 (unfavourable) Expressed in all Expressed in all testis: 215.1 PSMD7 MOV34, P40, Rpn8, S12 ENSG00000103035 Proteasome 26S subunit, non-ATPase 7 16 74296775-74306288 Enzymes, Predicted intracellular proteins Evidence at protein level CAB019379, HPA049824, HPA056069 Approved Validated Nucleoplasm Liver cancer:7.71e-6 (unfavourable), Head and neck cancer:6.64e-5 (unfavourable) Expressed in all Expressed in all prostate: 109.5 PSMD8 HIP6, HYPF, Nin1p, p31, Rpn12, S14 ENSG00000099341 Proteasome 26S subunit, non-ATPase 8 19 38374536-38383824 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006702, CAB021101 Supported Approved Nuclear speckles
Cytosol Endometrial cancer:3.84e-4 (unfavourable), Renal cancer:4.66e-4 (unfavourable) Expressed in all Expressed in all testis: 194.6 PSMD9 p27, Rpn4 ENSG00000110801 Proteasome 26S subunit, non-ATPase 9 12 121888731-121918297 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040512, HPA044220 Supported Supported Plasma membrane
Cytosol Liver cancer:1.32e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 17.9 PSME1 IFI5111, PA28alpha ENSG00000092010 Proteasome activator subunit 1 14 24136158-24138967 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006632 Approved Breast cancer:8.87e-5 (favourable), Thyroid cancer:4.60e-4 (favourable) Expressed in all Expressed in all lymph node: 334.5 PSME2 PA28beta ENSG00000100911 Proteasome activator subunit 2 14 24143362-24147570 Predicted intracellular proteins Evidence at protein level HPA062661 Approved Nucleus Renal cancer:3.47e-5 (unfavourable), Breast cancer:1.27e-4 (favourable) Expressed in all Expressed in all duodenum: 296.0 PSME3 Ki, PA28-gamma, PA28G, REG-GAMMA ENSG00000131467 Proteasome activator subunit 3 17 42824385-42843758 Predicted intracellular proteins Evidence at protein level CAB008388, HPA012510 Supported Validated Nucleoplasm Liver cancer:5.41e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 104.4 PSME4 KIAA0077, PA200 ENSG00000068878 Proteasome activator subunit 4 2 53864067-53970840 Predicted intracellular proteins Evidence at protein level HPA060922 Approved Supported Nucleoplasm Liver cancer:4.84e-4 (unfavourable), Endometrial cancer:8.99e-4 (unfavourable) Expressed in all Expressed in all testis: 77.7 PSMF1 PI31 ENSG00000125818 Proteasome inhibitor subunit 1 20 1113263-1189415 Predicted intracellular proteins Evidence at protein level HPA041122, HPA041300 Approved Validated Cytosol Expressed in all Expressed in all testis: 135.7 PSMG1 c21-LRP, DSCR2, LRPC21, PAC1 ENSG00000183527 Proteasome (prosome, macropain) assembly chaperone 1 21 39174769-39183851 Predicted intracellular proteins Evidence at protein level HPA057193, HPA070225 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Renal cancer:3.58e-5 (unfavourable) Expressed in all Expressed in all testis: 68.5 PSMG2 CLAST3, HCCA3, HsT1707, MDS003, MGC15092, PAC2, TNFSF5IP1 ENSG00000128789 Proteasome (prosome, macropain) assembly chaperone 2 18 12658043-12725740 Predicted intracellular proteins Evidence at protein level HPA041517, HPA046741 Uncertain Approved Nucleus
Nuclear bodies Ovarian cancer:3.09e-4 (favourable) Expressed in all Expressed in all testis: 171.5 PSMG3 C7orf48, MGC10911, PAC3 ENSG00000157778 Proteasome (prosome, macropain) assembly chaperone 3 7 1567330-1571005 Predicted intracellular proteins Evidence at protein level HPA023876 Approved Liver cancer:2.40e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 46.9 PSMG4 C6orf86, PAC4 ENSG00000180822 Proteasome (prosome, macropain) assembly chaperone 4 6 3231403-3303373 Predicted intracellular proteins Evidence at protein level HPA067652 Approved Nucleus
Mitochondria Renal cancer:7.45e-4 (unfavourable) Expressed in all Expressed in all epididymis: 26.3 PSPC1 FLJ10955, PSP1 ENSG00000121390 Paraspeckle component 1 13 19674752-19783019 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA038904 Supported Approved Nucleoplasm
Nucleoli fibrillar center Thyroid cancer:1.46e-4 (favourable), Liver cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all testis: 45.2 PSPH PSP ENSG00000146733 Phosphoserine phosphatase 7 56011051-56051604 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA020376, HPA029515 Approved Approved Cytosol Liver cancer:2.75e-5 (unfavourable), Breast cancer:2.30e-4 (unfavourable), Pancreatic cancer:3.77e-4 (favourable) Expressed in all Expressed in all fallopian tube: 25.2 PTAR1 ENSG00000188647 Protein prenyltransferase alpha subunit repeat containing 1 9 69709522-69759959 Predicted intracellular proteins Evidence at protein level HPA021248 Uncertain Approved Microtubule organizing center
Rods & Rings Renal cancer:4.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 34.9 PTBP1 HNRNP-I, HNRPI, pPTB, PTB, PTB-1, PTB2, PTB3, PTB4 ENSG00000011304 Polypyrimidine tract binding protein 1 19 797075-812327 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013507 Supported Supported Nucleoplasm Liver cancer:2.71e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 169.8 PTBP3 DKFZp781I1117, ROD1 ENSG00000119314 Polypyrimidine tract binding protein 3 9 112217716-112333667 Predicted intracellular proteins Evidence at protein level HPA048374 Approved Nucleus Pancreatic cancer:1.22e-4 (unfavourable), Lung cancer:2.10e-4 (unfavourable), Renal cancer:2.51e-4 (favourable) Expressed in all Expressed in all testis: 43.9 PTCD3 DKFZp666K071, FLJ20758 ENSG00000132300 Pentatricopeptide repeat domain 3 2 86106182-86142157 Predicted intracellular proteins Evidence at protein level HPA041154, HPA041382 Supported Validated Mitochondria Stomach cancer:6.77e-4 (favourable), Urothelial cancer:6.86e-4 (favourable) Expressed in all Expressed in all testis: 31.2 PTDSS2 PSS2 ENSG00000174915 Phosphatidylserine synthase 2 11 448268-491399 Enzymes, Predicted membrane proteins Evidence at protein level HPA038928, HPA038929 Approved Liver cancer:5.12e-9 (unfavourable) Expressed in all Expressed in all testis: 25.4 PTER ENSG00000165983 Phosphotriesterase related 10 16436943-16513745 Predicted intracellular proteins Evidence at protein level HPA038044, HPA038045 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.52e-6 (favourable), Liver cancer:2.11e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 42.9 PTGDS L-PGDS, PGDS ENSG00000107317 Prostaglandin D2 synthase 21kDa (brain) 9 136977505-136985435 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA004938, CAB009916 Approved Renal cancer:1.19e-7 (unfavourable) Expressed in all Expressed in all testis: 2586.0 PTGER4 EP4 ENSG00000171522 Prostaglandin E receptor 4 (subtype EP4) 5 40679498-40693735 FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA011226, HPA012756 Approved Urothelial cancer:2.48e-4 (favourable) Expressed in all Expressed in all bone marrow: 48.1 PTGES2 C9orf15, FLJ14038 ENSG00000148334 Prostaglandin E synthase 2 9 128120693-128128462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020631, HPA020733 Approved Approved Mitochondria Renal cancer:5.83e-7 (favourable) Expressed in all Expressed in all skeletal muscle: 35.1 PTGES3 cPGES, p23, TEBP ENSG00000110958 Prostaglandin E synthase 3 (cytosolic) 12 56663341-56688408 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034319, HPA038672, HPA038673 Approved Supported Nucleoplasm
Cytosol Liver cancer:4.44e-6 (unfavourable), Breast cancer:2.15e-5 (unfavourable), Ovarian cancer:4.36e-4 (favourable) Expressed in all Expressed in all fallopian tube: 344.4 PTGR1 LTB4DH, ZADH3 ENSG00000106853 Prostaglandin reductase 1 9 111549722-111599855 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036724 Supported Renal cancer:5.53e-4 (favourable) Expressed in all Expressed in all small intestine: 321.1 PTK2 FADK, FAK, FAK1, PPP1R71 ENSG00000169398 Protein tyrosine kinase 2 8 140657900-141002216 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001842, CAB004036, HPA029671 Approved Supported Vesicles
Focal adhesion sites
Cytosol Breast cancer:3.21e-4 (unfavourable), Endometrial cancer:9.11e-4 (unfavourable) Expressed in all Expressed in all placenta: 106.5 PTK2B CADTK, CAKB, FAK2, PTK, PYK2, RAFTK ENSG00000120899 Protein tyrosine kinase 2 beta 8 27311482-27459391 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003850, HPA026091, HPA026276 Approved Validated Plasma membrane
Cytosol Cervical cancer:3.32e-4 (favourable), Thyroid cancer:5.11e-4 (favourable) Expressed in all Expressed in all lymph node: 100.2 PTMA TMSA ENSG00000187514 Prothymosin, alpha 2 231706895-231713541 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047183, HPA052651 Approved Validated Nucleus
Cytosol Renal cancer:1.99e-7 (unfavourable), Liver cancer:3.61e-4 (unfavourable), Cervical cancer:6.56e-4 (favourable) Expressed in all Expressed in all lymph node: 1641.4 PTMS ParaT ENSG00000159335 Parathymosin 12 6765516-6770952 Predicted intracellular proteins Evidence at protein level HPA038186 Approved Approved Nucleus
Nucleoli Renal cancer:6.18e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 130.9 PTOV1 ENSG00000104960 Prostate tumor overexpressed 1 19 49850735-49860744 Predicted intracellular proteins Evidence at protein level HPA051812 Supported Nucleus Colorectal cancer:6.64e-4 (unfavourable), Pancreatic cancer:9.20e-4 (favourable) Expressed in all Expressed in all adrenal gland: 62.2 PTP4A1 PRL-1, PTPCAAX1 ENSG00000112245 Protein tyrosine phosphatase type IVA, member 1 6 63521761-63583587 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003281 Approved Cervical cancer:5.53e-4 (unfavourable) Expressed in all Expressed in all liver: 354.2 PTP4A2 HU-PP-1, OV-1, PRL-2, ptp-IV1a, PTP4A, PTPCAAX2 ENSG00000184007 Protein tyrosine phosphatase type IVA, member 2 1 31906421-31944856 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003281, CAB011204 Uncertain Renal cancer:5.10e-11 (unfavourable), Liver cancer:2.62e-5 (unfavourable), Urothelial cancer:2.72e-5 (favourable) Expressed in all Expressed in all thyroid gland: 278.8 PTPMT1 DUSP23, MOSP, PLIP ENSG00000110536 Protein tyrosine phosphatase, mitochondrial 1 11 47565430-47573461 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040348, HPA043932 Approved Supported Mitochondria Liver cancer:3.04e-5 (unfavourable) Expressed in all Expressed in all testis: 89.5 PTPN1 PTP1B ENSG00000196396 Protein tyrosine phosphatase, non-receptor type 1 20 50510321-50585241 Enzymes, Predicted membrane proteins Evidence at protein level CAB009329, HPA012542, CAB015217 Approved Validated Endoplasmic reticulum Expressed in all Expressed in all appendix: 62.0 PTPN11 BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2 ENSG00000179295 Protein tyrosine phosphatase, non-receptor type 11 12 112418351-112509913 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB005377 Approved Supported Nucleus
Nucleoli
Actin filaments
Cytosol Expressed in all Expressed in all cerebral cortex: 124.6 PTPN12 PTP-PEST, PTPG1 ENSG00000127947 Protein tyrosine phosphatase, non-receptor type 12 7 77537275-77640071 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007097 Approved Approved Plasma membrane
Cytosol Renal cancer:7.27e-6 (unfavourable), Cervical cancer:1.15e-4 (unfavourable), Pancreatic cancer:2.01e-4 (unfavourable), Liver cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all placenta: 106.3 PTPN18 BDP1 ENSG00000072135 Protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 2 130356007-130375409 Enzymes, Predicted intracellular proteins Evidence at protein level CAB012174 Uncertain Expressed in all Expressed in all lymph node: 48.0 PTPN2 PTPT, TC-PTP, TCELLPTP, TCPTP ENSG00000175354 Protein tyrosine phosphatase, non-receptor type 2 18 12785478-12929643 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015004, HPA046176 Supported Validated Nucleoplasm Renal cancer:1.20e-8 (unfavourable), Ovarian cancer:1.37e-4 (favourable) Expressed in all Expressed in all lymph node: 53.2 PTPN23 DKFZP564F0923, HD-PTP, KIAA1471 ENSG00000076201 Protein tyrosine phosphatase, non-receptor type 23 3 47381011-47413441 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016845 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:1.82e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.0 PTPN9 MEG2 ENSG00000169410 Protein tyrosine phosphatase, non-receptor type 9 15 75463251-75579289 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041922 Approved Approved Vesicles Renal cancer:2.49e-6 (favourable) Expressed in all Expressed in all thyroid gland: 54.6 PTPRA HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA ENSG00000132670 Protein tyrosine phosphatase, receptor type, A 20 2864184-3039076 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA029412, CAB034366, HPA069480 Approved Approved Nucleus
Vesicles Renal cancer:3.29e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 167.8 PTPRC CD45, GP180, LCA, T200 ENSG00000081237 Protein tyrosine phosphatase, receptor type, C 1 198638671-198757283 Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB000052, HPA000440, CAB002800, CAB056154, CAB068221 Supported Renal cancer:2.42e-4 (unfavourable) Expressed in all Expressed in all lymph node: 378.0 PTPRS ENSG00000105426 Protein tyrosine phosphatase, receptor type, S 19 5158495-5340803 Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054747 Approved Plasma membrane
Cytosol Pancreatic cancer:1.07e-4 (favourable), Renal cancer:1.70e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 70.8 PTRF cavin-1, CAVIN1 ENSG00000177469 Polymerase I and transcript release factor 17 42402452-42423517 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049838, HPA074213 Supported Supported Vesicles
Plasma membrane Urothelial cancer:5.87e-4 (unfavourable), Ovarian cancer:5.92e-4 (unfavourable), Colorectal cancer:6.36e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 342.2 PTRH1 C9orf115, PTH1 ENSG00000187024 Peptidyl-tRNA hydrolase 1 homolog 9 127692978-127724873 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021223 Uncertain Not detected Expressed in all adipose tissue: 11.1 PTRH2 BIT1, CFAP37, CGI-147, PTH2 ENSG00000141378 Peptidyl-tRNA hydrolase 2 17 59674636-59707626 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA012897 Supported Supported Mitochondria Renal cancer:1.01e-8 (unfavourable), Liver cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all epididymis: 43.1 PTRHD1 C2orf79, LOC391356 ENSG00000184924 Peptidyl-tRNA hydrolase domain containing 1 2 24789734-24793382 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019951 Approved Approved Nucleoplasm Renal cancer:2.31e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 14.1 PTS PTPS ENSG00000150787 6-pyruvoyltetrahydropterin synthase 11 112226365-112269955 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001481 Uncertain Approved Cytosol Expressed in all Expressed in all adrenal gland: 67.2 PTTG1IP C21orf1, C21orf3, PBF ENSG00000183255 Pituitary tumor-transforming 1 interacting protein 21 44849585-44873903 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB034146, HPA061827 Uncertain Supported Nucleoplasm Pancreatic cancer:2.28e-4 (unfavourable), Stomach cancer:5.40e-4 (unfavourable), Cervical cancer:8.61e-4 (unfavourable) Expressed in all Expressed in all placenta: 241.9 PUDP DXF68S1E, FAM16AX, GS1, HDHD1, HDHD1A ENSG00000130021 Pseudouridine 5'-phosphatase X 7048920-7148190 Enzymes, Predicted intracellular proteins Evidence at protein level Thyroid cancer:4.80e-4 (favourable), Pancreatic cancer:7.27e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 31.1 PUF60 FIR, RoBPI, SIAHBP1 ENSG00000179950 Poly-U binding splicing factor 60KDa 8 143816344-143829859 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045733, HPA052096, HPA059714 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 26.2 PUM1 KIAA0099, PUMH1 ENSG00000134644 Pumilio RNA-binding family member 1 1 30931506-31065991 Predicted intracellular proteins Evidence at protein level HPA027424, HPA027449 Approved Supported Nucleus
Cytosol Renal cancer:7.62e-8 (favourable), Liver cancer:3.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 71.9 PUM2 KIAA0235, PUMH2 ENSG00000055917 Pumilio RNA-binding family member 2 2 20248691-20352234 Predicted intracellular proteins Evidence at protein level HPA030316, HPA049670 Approved Validated Cytosol Liver cancer:5.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 97.7 PUM3 HA-8, hPUF-A, KIAA0020, PEN, PUF6, XTP5 ENSG00000080608 Pumilio RNA-binding family member 3 9 2720469-2844241 Predicted intracellular proteins Evidence at protein level HPA002353 Approved Supported Nucleoli Liver cancer:4.89e-5 (unfavourable), Prostate cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all appendix: 29.3 PURB PURBETA ENSG00000146676 Purine-rich element binding protein B 7 44876293-44885361 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048766 Supported Nucleus Expressed in all Expressed in all cerebral cortex: 24.6 PUS1 ENSG00000177192 Pseudouridylate synthase 1 12 131929200-131945896 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA051636, HPA057593 Approved Supported Nucleus
Mitochondria Renal cancer:3.49e-8 (unfavourable) Expressed in all Expressed in all lymph node: 21.6 PUS3 FKSG32 ENSG00000110060 Pseudouridylate synthase 3 11 125893485-125903221 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038040, HPA063802 Uncertain Approved Nucleus
Cytosol Head and neck cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all liver: 16.9 PUSL1 FLJ90811 ENSG00000169972 Pseudouridylate synthase-like 1 1 1308567-1311677 Predicted intracellular proteins Evidence at protein level HPA032057, HPA039999 Uncertain Validated Vesicles Renal cancer:1.62e-5 (unfavourable), Liver cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all skin: 9.1 PVR CD155, HVED, Necl-5, NECL5, PVS, Tage4 ENSG00000073008 Poliovirus receptor 19 44643798-44663583 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012568 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Cervical cancer:1.29e-4 (unfavourable), Urothelial cancer:2.75e-4 (unfavourable), Lung cancer:9.30e-4 (unfavourable) Expressed in all Expressed in all placenta: 16.9 PVRL2 CD112, HVEB, PRR2, PVRR2 ENSG00000130202 Poliovirus receptor-related 2 (herpesvirus entry mediator B) 19 44846175-44889228 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012759, CAB026138, HPA073459 Supported Uncertain Nucleoli fibrillar center
Cell Junctions Expressed in all Expressed in all placenta: 111.0 PWP1 IEF-SSP-9502 ENSG00000136045 PWP1 homolog, endonuclein 12 107685732-107713167 Predicted intracellular proteins Evidence at protein level HPA038708 Approved Nucleoli
Golgi apparatus Liver cancer:1.40e-5 (unfavourable), Renal cancer:2.26e-4 (unfavourable), Head and neck cancer:9.65e-4 (unfavourable) Expressed in all Expressed in all testis: 55.1 PWWP2A KIAA1935 ENSG00000170234 PWWP domain containing 2A 5 160061801-160119423 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA046733, HPA058233 Uncertain Supported Nucleoplasm
Focal adhesion sites Urothelial cancer:3.51e-4 (favourable), Renal cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 15.4 PXK FLJ20335 ENSG00000168297 PX domain containing serine/threonine kinase 3 58332880-58426126 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024068 Supported Supported Plasma membrane
Microtubule organizing center
Cytosol Lung cancer:5.68e-4 (favourable) Expressed in all Expressed in all thyroid gland: 124.3 PXMP2 PMP22 ENSG00000176894 Peroxisomal membrane protein 2, 22kDa 12 132687606-132704991 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:2.75e-4 (favourable), Head and neck cancer:9.84e-4 (unfavourable) Expressed in all Expressed in all liver: 119.8 PXMP4 PMP24 ENSG00000101417 Peroxisomal membrane protein 4, 24kDa 20 33702754-33720319 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA050077 Approved Approved Nucleoli fibrillar center
Peroxisomes Renal cancer:4.03e-10 (favourable), Lung cancer:3.88e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 29.8 PXN ENSG00000089159 Paxillin 12 120210439-120265771 Predicted intracellular proteins Evidence at protein level CAB003841, HPA051309 Supported Validated Focal adhesion sites
Cytosol Head and neck cancer:3.72e-5 (unfavourable), Glioma:6.11e-5 (unfavourable), Liver cancer:7.12e-5 (unfavourable), Lung cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all placenta: 112.3 PXYLP1 ACPL2, FLJ23751 ENSG00000155893 2-phosphoxylose phosphatase 1 3 141228726-141294906 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017243 Approved Expressed in all Expressed in all epididymis: 178.7 PYCR2 P5CR2 ENSG00000143811 Pyrroline-5-carboxylate reductase family, member 2 1 225919877-225924340 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA056873 Approved Approved Mitochondria Renal cancer:1.42e-6 (unfavourable), Colorectal cancer:5.02e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 71.0 PYGB ENSG00000100994 Phosphorylase, glycogen; brain 20 25248069-25298014 Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031067 Approved Approved Cytosol Lung cancer:1.10e-4 (unfavourable), Urothelial cancer:1.43e-4 (unfavourable), Liver cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 148.6 PYGO2 ENSG00000163348 Pygopus family PHD finger 2 1 154957026-154963853 Predicted intracellular proteins Evidence at protein level HPA023689 Supported Approved Nucleoplasm Liver cancer:3.88e-6 (unfavourable), Urothelial cancer:1.76e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 50.7 PYM1 PYM, WIBG ENSG00000170473 PYM homolog 1, exon junction complex associated factor 12 55901413-55932618 Predicted intracellular proteins Evidence at protein level CAB012803, HPA039717, HPA046200 Supported Supported Nucleus
Nucleoli
Cell Junctions
Cytosol Urothelial cancer:1.34e-4 (favourable), Liver cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all esophagus: 50.5 PYROXD1 DKFZp762G094, FLJ22028 ENSG00000121350 Pyridine nucleotide-disulphide oxidoreductase domain 1 12 21437615-21471252 Predicted intracellular proteins Evidence at protein level HPA038319, HPA038320 Uncertain Approved Nuclear speckles Urothelial cancer:1.70e-4 (favourable) Expressed in all Expressed in all thyroid gland: 26.7 PYURF PreY ENSG00000145337 PIGY upstream reading frame 4 88520985-88523813 Predicted intracellular proteins Evidence at protein level HPA036455 Uncertain Approved Nucleoplasm Expressed in all Expressed in all epididymis: 93.7 QARS ENSG00000172053 Glutaminyl-tRNA synthetase 3 49095932-49105135 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036986, HPA036987 Supported Validated Cytosol Renal cancer:5.60e-6 (favourable), Breast cancer:1.43e-4 (favourable) Expressed in all Expressed in all rectum: 121.1 QDPR DHPR, PKU2, SDR33C1 ENSG00000151552 Quinoid dihydropteridine reductase 4 17460261-17512234 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA058951, HPA065649 Supported Approved Mitochondria Renal cancer:7.84e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 226.9 QKI QK3 ENSG00000112531 QKI, KH domain containing, RNA binding 6 163414000-163578596 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA019123, CAB022602 Supported Supported Supported Nucleoplasm Renal cancer:2.31e-5 (unfavourable), Liver cancer:1.27e-4 (unfavourable), Stomach cancer:3.69e-4 (unfavourable) Tissue enriched Expressed in all cerebral cortex: 360.6 QPRT QPRTase ENSG00000103485 Quinolinate phosphoribosyltransferase 16 29679008-29698699 Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA011887 Approved Breast cancer:5.10e-5 (unfavourable), Glioma:7.45e-4 (unfavourable) Expressed in all Expressed in all kidney: 111.8 QRICH1 FLJ20259 ENSG00000198218 Glutamine-rich 1 3 49029707-49094363 Predicted intracellular proteins Evidence at protein level HPA037677, HPA037678 Approved Validated Nucleoplasm Ovarian cancer:7.46e-4 (favourable) Expressed in all Expressed in all testis: 78.8 QRSL1 DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA ENSG00000130348 Glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 6 106629578-106668417 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029585, HPA029587 Approved Approved Vesicles
Centrosome Liver cancer:7.97e-5 (unfavourable), Renal cancer:3.83e-4 (favourable) Expressed in all Expressed in all lymph node: 18.9 QSER1 FLJ21924 ENSG00000060749 Glutamine and serine rich 1 11 32893178-32993316 Predicted intracellular proteins Evidence at protein level HPA005682 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:5.27e-5 (unfavourable), Liver cancer:7.94e-5 (unfavourable), Renal cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all testis: 17.6 QSOX1 QSCN6 ENSG00000116260 Quiescin Q6 sulfhydryl oxidase 1 1 180154834-180204030 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA042127, HPA056243 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:1.86e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 234.2 QSOX2 DKFZp762A2013, QSCN6L1, SOXN ENSG00000165661 Quiescin Q6 sulfhydryl oxidase 2 9 136206333-136245841 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012716, HPA017280 Uncertain Validated Nucleoplasm
Golgi apparatus Renal cancer:9.64e-6 (unfavourable) Expressed in all Expressed in all lymph node: 20.9 QTRT1 TGT ENSG00000213339 Queuine tRNA-ribosyltransferase 1 19 10701430-10713437 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042695, HPA048651, HPA049440 Approved Approved Mitochondria Renal cancer:1.13e-6 (unfavourable), Cervical cancer:7.63e-5 (favourable), Pancreatic cancer:2.13e-4 (favourable), Head and neck cancer:4.90e-4 (favourable) Expressed in all Expressed in all thyroid gland: 25.4 QTRTD1 FLJ12960 ENSG00000151576 Queuine tRNA-ribosyltransferase domain containing 1 3 114005833-114088422 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036827, HPA036828 Uncertain Approved Nucleoplasm
Intermediate filaments Prostate cancer:6.95e-4 (unfavourable) Expressed in all Expressed in all spleen: 16.6 R3HCC1 DKFZp564N123 ENSG00000104679 R3H domain and coiled-coil containing 1 8 23270120-23296279 Predicted intracellular proteins Evidence at protein level HPA023073, HPA023153 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:6.80e-5 (favourable), Colorectal cancer:4.08e-4 (favourable), Pancreatic cancer:8.66e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 43.1 R3HCC1L C10orf28, GIDRP86, PSORT ENSG00000166024 R3H domain and coiled-coil containing 1-like 10 98134624-98244897 Predicted intracellular proteins Evidence at protein level HPA037367 Approved Approved Nucleoplasm
Nuclear speckles Expressed in all Expressed in all testis: 38.7 R3HDM1 KIAA0029, R3HDM ENSG00000048991 R3H domain containing 1 2 135531455-135725270 Predicted intracellular proteins Evidence at protein level HPA030936 Approved Nucleoplasm
Cytosol Renal cancer:5.83e-7 (unfavourable), Lung cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 82.5 R3HDM2 KIAA1002 ENSG00000179912 R3H domain containing 2 12 57253762-57431005 Predicted intracellular proteins Evidence at protein level HPA038327, HPA038328 Approved Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 51.9 R3HDM4 C19orf22, MGC16353 ENSG00000198858 R3H domain containing 4 19 896503-913245 Predicted intracellular proteins Evidence at protein level HPA043025, HPA048638 Uncertain Approved Nucleus
Cytosol Endometrial cancer:7.33e-6 (favourable) Expressed in all Expressed in all appendix: 69.6 RAB10 ENSG00000084733 RAB10, member RAS oncogene family 2 26034107-26137454 Predicted intracellular proteins Evidence at protein level HPA045611 Approved Liver cancer:1.99e-5 (unfavourable), Pancreatic cancer:7.37e-5 (unfavourable), Endometrial cancer:7.40e-4 (unfavourable) Expressed in all Expressed in all esophagus: 186.4 RAB11A YL8 ENSG00000103769 RAB11A, member RAS oncogene family 15 65726054-65891991 Predicted intracellular proteins Evidence at protein level CAB013097, HPA051697, HPA060686 Approved Supported Microtubule organizing center Renal cancer:1.46e-5 (favourable), Pancreatic cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all esophagus: 526.8 RAB11B H-YPT3 ENSG00000185236 RAB11B, member RAS oncogene family 19 8389981-8404434 Predicted intracellular proteins Evidence at protein level HPA054396 Approved Vesicles
Microtubule organizing center Pancreatic cancer:7.58e-5 (favourable), Renal cancer:2.06e-4 (favourable), Cervical cancer:2.08e-4 (favourable) Expressed in all Expressed in all thyroid gland: 152.7 RAB11FIP1 FLJ22524, FLJ22622, Rab11-FIP1, RCP ENSG00000156675 RAB11 family interacting protein 1 (class I) 8 37858618-37899467 Predicted intracellular proteins Evidence at protein level CAB017037, HPA023904, HPA024010, HPA025960 Supported Validated Vesicles Renal cancer:1.14e-6 (favourable), Head and neck cancer:6.61e-4 (favourable) Mixed Expressed in all lung: 112.0 RAB11FIP2 KIAA0941, nRip11, Rab11-FIP2 ENSG00000107560 RAB11 family interacting protein 2 (class I) 10 118004916-118046603 Predicted intracellular proteins Evidence at protein level HPA037726 Approved Supported Nucleoplasm
Vesicles Renal cancer:9.69e-5 (favourable) Expressed in all Expressed in all seminal vesicle: 36.2 RAB11FIP3 eferin, KIAA0665, Rab11-FIP3 ENSG00000090565 RAB11 family interacting protein 3 (class II) 16 425619-523011 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA028088, HPA028631, HPA030086 Approved Supported Vesicles
Cytokinetic bridge
Microtubule organizing center Pancreatic cancer:3.16e-5 (favourable), Liver cancer:9.87e-5 (unfavourable), Endometrial cancer:1.22e-4 (favourable), Renal cancer:7.99e-4 (favourable) Expressed in all Expressed in all kidney: 56.8 RAB12 ENSG00000206418 RAB12, member RAS oncogene family 18 8609445-8639381 Predicted intracellular proteins Evidence at protein level HPA040727 Approved Approved Vesicles Expressed in all Expressed in all skeletal muscle: 67.4 RAB13 ENSG00000143545 RAB13, member RAS oncogene family 1 153981617-153986358 Predicted intracellular proteins Evidence at protein level HPA003996 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all prostate: 153.9 RAB14 FBP, RAB-14 ENSG00000119396 RAB14, member RAS oncogene family 9 121178137-121223014 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026419, CAB037066 Approved Supported Vesicles Renal cancer:1.79e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 83.6 RAB15 ENSG00000139998 RAB15, member RAS oncogene family 14 64945814-64972776 Predicted intracellular proteins Evidence at protein level HPA041177 Uncertain Approved Vesicles
Microtubule organizing center Liver cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 63.0 RAB18 ENSG00000099246 RAB18, member RAS oncogene family 10 27504174-27542237 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA025928 Uncertain Expressed in all Expressed in all cerebral cortex: 88.2 RAB1A RAB1, YPT1 ENSG00000138069 RAB1A, member RAS oncogene family 2 65070701-65130106 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005331, HPA056141 Approved Supported Endoplasmic reticulum
Cytosol Head and neck cancer:4.19e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 217.2 RAB1B ENSG00000174903 RAB1B, member RAS oncogene family 11 66268533-66277492 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010225, HPA056141 Approved Supported Endoplasmic reticulum
Golgi apparatus Renal cancer:1.09e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 181.5 RAB22A ENSG00000124209 RAB22A, member RAS oncogene family 20 58309696-58367507 Predicted intracellular proteins Evidence at protein level HPA058894, HPA066920 Approved Uncertain Centrosome Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.8 RAB24 ENSG00000169228 RAB24, member RAS oncogene family 5 177301198-177303744 Predicted intracellular proteins Evidence at protein level HPA034945 Uncertain Focal adhesion sites Renal cancer:2.54e-7 (unfavourable), Liver cancer:7.56e-5 (unfavourable), Head and neck cancer:6.22e-4 (favourable) Expressed in all Expressed in all spleen: 40.8 RAB28 ENSG00000157869 RAB28, member RAS oncogene family 4 13361354-13484365 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044575 Approved Urothelial cancer:1.61e-4 (favourable) Expressed in all Expressed in all testis: 67.4 RAB29 RAB7L, RAB7L1 ENSG00000117280 RAB29, member RAS oncogene family 1 205767986-205775460 Predicted intracellular proteins Evidence at protein level CAB020822, HPA026303 Approved Approved Nuclear membrane
Nucleoli Endometrial cancer:1.82e-5 (unfavourable), Liver cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all kidney: 75.6 RAB2A RAB2 ENSG00000104388 RAB2A, member RAS oncogene family 8 60516857-60623627 Predicted intracellular proteins Evidence at protein level CAB018781 Approved Breast cancer:8.22e-4 (unfavourable), Endometrial cancer:9.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 108.3 RAB2B FLJ14824 ENSG00000129472 RAB2B, member RAS oncogene family 14 21459020-21476973 Predicted intracellular proteins Evidence at protein level HPA050292 Uncertain Expressed in all Expressed in all epididymis: 22.5 RAB30 ENSG00000137502 RAB30, member RAS oncogene family 11 82973133-83071923 Predicted intracellular proteins Evidence at protein level HPA054514, HPA060565 Approved Validated Vesicles Expressed in all Expressed in all tonsil: 29.7 RAB31 Rab22B ENSG00000168461 RAB31, member RAS oncogene family 18 9708165-9862551 Predicted intracellular proteins Evidence at protein level HPA019717 Approved Expressed in all Expressed in all cerebral cortex: 170.3 RAB32 ENSG00000118508 RAB32, member RAS oncogene family 6 146543693-146554965 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025731 Approved Approved Cytosol Liver cancer:1.08e-7 (unfavourable), Colorectal cancer:1.56e-4 (favourable), Endometrial cancer:6.51e-4 (unfavourable), Renal cancer:8.62e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 92.1 RAB33B DKFZP434G099 ENSG00000172007 RAB33B, member RAS oncogene family 4 139453232-139476609 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA048367 Uncertain Urothelial cancer:9.19e-4 (favourable) Expressed in all Expressed in all endometrium: 13.0 RAB34 RAB39, RAH ENSG00000109113 RAB34, member RAS oncogene family 17 28714281-28718429 Predicted intracellular proteins Evidence at protein level HPA021366 Approved Renal cancer:1.64e-7 (unfavourable), Thyroid cancer:1.06e-5 (favourable) Expressed in all Expressed in all endometrium: 132.7 RAB35 H-ray ENSG00000111737 RAB35, member RAS oncogene family 12 120095095-120117502 Predicted intracellular proteins Evidence at protein level HPA054146 Approved Liver cancer:6.46e-6 (unfavourable), Lung cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all appendix: 39.1 RAB3GAP1 KIAA0066, RAB3GAP, RAB3GAP130, WARBM1 ENSG00000115839 RAB3 GTPase activating protein subunit 1 (catalytic) 2 135052265-135176394 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034494, HPA034495 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:2.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 55.8 RAB3GAP2 DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69 ENSG00000118873 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1 220148293-220272454 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026273, HPA027299 Approved Supported Plasma membrane
Cytosol Breast cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.7 RAB40C RARL, RASL8C ENSG00000197562 RAB40C, member RAS oncogene family 16 589357-629272 Predicted intracellular proteins Evidence at protein level Liver cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all skin: 26.6 RAB4A HRES-1/RAB4, RAB4 ENSG00000168118 RAB4A, member RAS oncogene family 1 229271062-229305894 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all prostate: 57.2 RAB4B FLJ78649, MGC52123 ENSG00000167578 RAB4B, member RAS oncogene family 19 40778216-40796938 Predicted intracellular proteins Evidence at protein level Urothelial cancer:1.99e-5 (favourable), Renal cancer:1.28e-4 (unfavourable), Pancreatic cancer:2.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 56.2 RAB5A RAB5 ENSG00000144566 RAB5A, member RAS oncogene family 3 19947079-19985175 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004567, HPA049354 Approved Expressed in all Expressed in all parathyroid gland: 78.1 RAB5B ENSG00000111540 RAB5B, member RAS oncogene family 12 55973913-55996683 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010224, HPA068337 Approved Supported Vesicles Breast cancer:2.24e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 172.6 RAB5C RAB5CL, RABL ENSG00000108774 RAB5C, member RAS oncogene family 17 42124976-42155044 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA003426, HPA004167 Approved Validated Endosomes Head and neck cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 179.8 RAB6A RAB6 ENSG00000175582 RAB6A, member RAS oncogene family 11 73675638-73761137 Predicted intracellular proteins Evidence at protein level CAB009936, HPA059131 Approved Supported Golgi apparatus Endometrial cancer:8.18e-5 (unfavourable), Liver cancer:1.34e-4 (unfavourable), Pancreatic cancer:2.24e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 269.8 RAB7A RAB7 ENSG00000075785 RAB7A, member RAS oncogene family 3 128726122-128814796 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006964, CAB037131 Supported Supported Lysosomes Liver cancer:9.89e-6 (unfavourable), Endometrial cancer:1.52e-4 (unfavourable), Pancreatic cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 271.1 RAB8A MEL, RAB8 ENSG00000167461 RAB8A, member RAS oncogene family 19 16111629-16134234 Predicted intracellular proteins Evidence at protein level HPA041945 Supported Nucleus
Plasma membrane Renal cancer:6.56e-5 (unfavourable), Thyroid cancer:1.71e-4 (favourable) Expressed in all Expressed in all small intestine: 65.9 RAB8B ENSG00000166128 RAB8B, member RAS oncogene family 15 63189469-63267782 Predicted intracellular proteins Evidence at protein level HPA074534 Supported Nucleoplasm
Vesicles Renal cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 50.7 RAB9A RAB9 ENSG00000123595 RAB9A, member RAS oncogene family X 13689121-13710506 Predicted intracellular proteins Evidence at protein level HPA003094, CAB016411 Supported Uncertain Nucleoplasm
Cytosol Renal cancer:3.35e-5 (favourable) Expressed in all Expressed in all adrenal gland: 63.9 RABAC1 PRA1, PRAF1, YIP3 ENSG00000105404 Rab acceptor 1 (prenylated) 19 41956681-41959390 Predicted membrane proteins Evidence at protein level CAB019320, HPA029171 Supported Approved Nuclear membrane
Nucleoli fibrillar center Expressed in all Expressed in all cerebral cortex: 107.6 RABEP1 neurocrescin, RAB5EP, rabaptin-5, RABPT5 ENSG00000029725 Rabaptin, RAB GTPase binding effector protein 1 17 5282265-5385812 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004549, HPA019669, HPA024235, HPA024691 Supported Validated Vesicles Pancreatic cancer:6.43e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 89.9 RABEP2 FLJ23282, FRA ENSG00000177548 Rabaptin, RAB GTPase binding effector protein 2 16 28904421-28936526 Predicted intracellular proteins Evidence at protein level HPA047641 Approved Supported Vesicles
Cytosol Renal cancer:1.24e-6 (favourable), Head and neck cancer:5.84e-4 (favourable) Expressed in all Expressed in all lymph node: 58.0 RABEPK bA65N13.1, RAB9P40 ENSG00000136933 Rab9 effector protein with kelch motifs 9 125200542-125234158 Predicted intracellular proteins Evidence at protein level HPA023920, HPA067106 Supported Uncertain Plasma membrane Expressed in all Expressed in all liver: 30.6 RABGAP1 GAPCenA, TBC1D11 ENSG00000011454 RAB GTPase activating protein 1 9 122940833-123104866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041651, HPA064860, HPA072273 Approved Validated Cytosol Renal cancer:6.06e-6 (favourable), Breast cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 66.1 RABGAP1L FLJ38519, HHL, KIAA0471, TBC1D18 ENSG00000152061 RAB GTPase activating protein 1-like 1 174159410-174995308 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054695 Uncertain Approved Nucleoli
Cytosol Lung cancer:1.16e-4 (favourable) Expressed in all Expressed in all heart muscle: 89.1 RABGEF1 rabex-5, RABEX5 ENSG00000154710 RAB guanine nucleotide exchange factor (GEF) 1 7 66682164-66811464 Predicted intracellular proteins Evidence at protein level HPA001407 Supported Nucleoli
Cytosol Glioma:2.90e-5 (unfavourable), Renal cancer:1.27e-4 (favourable) Expressed in all Expressed in all bone marrow: 54.0 RABGGTA PTAR3 ENSG00000100949 Rab geranylgeranyltransferase, alpha subunit 14 24265538-24271739 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043488 Approved Validated Nucleoplasm Thyroid cancer:1.51e-4 (favourable), Renal cancer:5.44e-4 (favourable) Expressed in all Expressed in all esophagus: 34.2 RABGGTB ENSG00000137955 Rab geranylgeranyltransferase, beta subunit 1 75786197-75795079 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026585, HPA027167, HPA030793 Approved Approved Supported Vesicles Renal cancer:1.12e-5 (unfavourable), Liver cancer:9.80e-5 (unfavourable) Expressed in all Expressed in all kidney: 68.8 RABL2B ENSG00000079974 RAB, member of RAS oncogene family-like 2B 22 50767501-50783663 Predicted intracellular proteins Evidence at protein level HPA042700, HPA044007 Approved Uncertain Plasma membrane
Cytosol Liver cancer:4.58e-5 (unfavourable), Endometrial cancer:5.58e-4 (favourable) Expressed in all Expressed in all epididymis: 109.0 RABL3 MGC23920 ENSG00000144840 RAB, member of RAS oncogene family-like 3 3 120686681-120742993 Predicted intracellular proteins Evidence at protein level HPA035150, HPA035151 Uncertain Approved Nucleoplasm Renal cancer:2.79e-5 (favourable) Expressed in all Expressed in all thyroid gland: 32.9 RABL6 bA216L13.9, C9orf86, FLJ10101, FLJ13045, Parf, pp8875, RBEL1 ENSG00000196642 RAB, member RAS oncogene family-like 6 9 136807943-136957733 Predicted intracellular proteins Evidence at protein level HPA044037, HPA050638 Uncertain Uncertain Nucleus
Centrosome
Cytosol Pancreatic cancer:1.46e-4 (favourable), Endometrial cancer:4.00e-4 (favourable), Stomach cancer:9.14e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 47.0 RABL6 ENSG00000282955 RAB, member RAS oncogene family-like 6 9 136808197-136840522 Predicted intracellular proteins Evidence at protein level HPA044037, HPA050638 Uncertain Uncertain Nucleus
Centrosome
Cytosol Expressed in all esophagus: 20.2 RAC1 p21-Rac1, Rac-1, TC-25 ENSG00000136238 Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 7 6374523-6403977 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB035994, HPA047820 Approved Approved Nucleus
Nucleoli
Cytosol Liver cancer:1.74e-5 (unfavourable), Pancreatic cancer:4.57e-5 (unfavourable), Renal cancer:2.11e-4 (unfavourable), Lung cancer:4.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 282.4 RAC2 EN-7 ENSG00000128340 Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 22 37225261-37244448 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB022946, HPA047820 Approved Renal cancer:1.06e-6 (unfavourable), Breast cancer:1.03e-5 (favourable) Expressed in all Expressed in all lymph node: 449.5 RAD17 CCYC, RAD17Sp, Rad24 ENSG00000152942 RAD17 checkpoint clamp loader component 5 69369293-69414801 Predicted intracellular proteins Evidence at protein level CAB004551, HPA005448 Approved Validated Nucleoplasm Renal cancer:5.79e-6 (favourable) Expressed in all Expressed in all testis: 39.2 RAD21 hHR21, KIAA0078, SCC1 ENSG00000164754 RAD21 cohesin complex component 8 116845935-116874866 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020044, CAB022065 Supported Validated Nucleoplasm Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all testis: 161.7 RAD23A HHR23A, MGC111083 ENSG00000179262 RAD23 homolog A, nucleotide excision repair protein 19 12945855-12953642 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA053901, HPA057003, HPA065599 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all skeletal muscle: 334.2 RAD23B HHR23B, HR23B, P58 ENSG00000119318 RAD23 homolog B, nucleotide excision repair protein 9 107283137-107332194 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029718, HPA029720, CAB033868 Supported Supported Nucleoplasm
Cytosol Head and neck cancer:2.58e-4 (unfavourable), Lung cancer:6.71e-4 (unfavourable) Expressed in all Expressed in all placenta: 110.0 RAD50 hRad50, RAD50-2 ENSG00000113522 RAD50 homolog, double strand break repair protein 5 132556019-132646344 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022103, CAB024979, HPA052291 Supported Validated Nucleoplasm Renal cancer:1.95e-4 (favourable), Cervical cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all epididymis: 21.2 RAD51C FANCO, RAD51L2 ENSG00000108384 RAD51 paralog C 17 58692573-58735611 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045198 Supported Nucleus
Vesicles
Cell Junctions
Mitochondria
Cytosol Liver cancer:8.68e-5 (unfavourable), Pancreatic cancer:5.33e-4 (favourable) Expressed in all Expressed in all testis: 37.1 RAD52 ENSG00000002016 RAD52 homolog, DNA repair protein 12 912077-990053 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA028957 Approved Nuclear speckles
Plasma membrane Renal cancer:2.22e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 13.5 RAD54L2 ARIP4, KIAA0809, SRISNF2L ENSG00000164080 RAD54-like 2 (S. cerevisiae) 3 51541144-51668667 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035004, HPA039992 Supported Nucleus
Cytosol Renal cancer:1.71e-5 (favourable) Expressed in all Expressed in all testis: 8.8 RAD9A RAD9 ENSG00000172613 RAD9 checkpoint clamp component A 11 67317871-67398410 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006725, HPA048155 Supported Validated Nucleoplasm Urothelial cancer:7.52e-6 (favourable), Renal cancer:2.82e-5 (unfavourable), Cervical cancer:6.95e-4 (favourable) Expressed in all Expressed in all fallopian tube: 14.9 RAF1 c-Raf, CRAF, Raf-1 ENSG00000132155 Raf-1 proto-oncogene, serine/threonine kinase 3 12583601-12664226 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA002640, CAB019291 Approved Approved Nuclear speckles Expressed in all Expressed in all parathyroid gland: 100.1 RAI1 DKFZP434A139, KIAA1820, MGC12824, SMCR, SMS ENSG00000108557 Retinoic acid induced 1 17 17681473-17811453 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023898, HPA054906 Validated Nucleoplasm Ovarian cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.3 RALA RAL ENSG00000006451 V-ral simian leukemia viral oncogene homolog A (ras related) 7 39623483-39708124 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA064515, HPA065232 Approved Supported Plasma membrane Liver cancer:5.32e-5 (unfavourable), Pancreatic cancer:6.30e-4 (unfavourable), Ovarian cancer:7.46e-4 (favourable) Expressed in all Expressed in all lung: 60.5 RALBP1 RIP, RIP1, RLIP76 ENSG00000017797 RalA binding protein 1 18 9475009-9538116 Predicted intracellular proteins, RAS pathway related proteins, Transporters Evidence at protein level CAB046010, HPA046651 Approved Approved Nuclear membrane
Vesicles
Cytosol Renal cancer:5.39e-6 (favourable), Ovarian cancer:8.47e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 69.8 RALGAPA1 DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1 ENSG00000174373 Ral GTPase activating protein, alpha subunit 1 (catalytic) 14 35538352-35809304 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000851 Approved Approved Mitochondria
Cytosol Renal cancer:9.76e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 50.5 RALGAPA2 AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2 ENSG00000188559 Ral GTPase activating protein, alpha subunit 2 (catalytic) 20 20389552-20712488 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042707, HPA043622 Uncertain Supported Plasma membrane
Cytosol Renal cancer:3.77e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.8 RALGAPB DKFZp781M2411, KIAA1219, RalGAPbeta ENSG00000170471 Ral GTPase activating protein, beta subunit (non-catalytic) 20 38472816-38578861 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051454 Approved Approved Nuclear speckles Renal cancer:7.25e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 45.4 RALGDS RalGEF, RGDS, RGF ENSG00000160271 Ral guanine nucleotide dissociation stimulator 9 133097720-133149334 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA025961, CAB032582 Approved Approved Nucleus Cervical cancer:4.19e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 53.0 RALGPS1 KIAA0351, RALGEF2, RALGPS1A ENSG00000136828 Ral GEF with PH domain and SH3 binding motif 1 9 126914774-127223166 Predicted intracellular proteins Evidence at protein level Renal cancer:6.20e-11 (favourable) Expressed in all Expressed in all small intestine: 32.7 RALY HNRPCL2, P542 ENSG00000125970 RALY heterogeneous nuclear ribonucleoprotein 20 33993646-34108308 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040971, HPA043614 Supported Validated Nucleoplasm Liver cancer:3.60e-4 (unfavourable) Expressed in all Expressed in all testis: 140.7 RAN ARA24, Gsp1, TC4 ENSG00000132341 RAN, member RAS oncogene family 12 130871879-130877678 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA063353 Uncertain Nucleus Liver cancer:9.99e-8 (unfavourable), Renal cancer:1.46e-7 (unfavourable), Prostate cancer:7.86e-5 (unfavourable) Expressed in all Expressed in all testis: 557.0 RANBP1 HTF9A ENSG00000099901 RAN binding protein 1 22 20115938-20127357 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB046463, HPA065868, HPA065931 Approved Supported Cytosol Renal cancer:1.16e-6 (unfavourable), Liver cancer:1.58e-6 (unfavourable) Expressed in all Expressed in all testis: 152.3 RANBP10 KIAA1464 ENSG00000141084 RAN binding protein 10 16 67723066-67806652 Predicted intracellular proteins Evidence at protein level Renal cancer:7.52e-4 (favourable) Expressed in all Expressed in all bone marrow: 26.8 RANBP2 ADANE, ANE1, NUP358 ENSG00000153201 RAN binding protein 2 2 108719481-108785811 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564 Supported Validated Nuclear membrane
Vesicles Expressed in all Expressed in all parathyroid gland: 73.6 RANBP3 ENSG00000031823 RAN binding protein 3 19 5916139-5978142 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA043375, HPA043389 Supported Validated Nucleoplasm Endometrial cancer:1.22e-5 (favourable), Pancreatic cancer:4.14e-4 (favourable), Thyroid cancer:8.14e-4 (favourable) Expressed in all Expressed in all testis: 60.1 RANBP6 ENSG00000137040 RAN binding protein 6 9 6011043-6015625 Predicted intracellular proteins Evidence at protein level HPA043748, HPA052684 Approved Supported Vesicles Renal cancer:1.34e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 26.3 RANBP9 RanBPM ENSG00000010017 RAN binding protein 9 6 13621498-13711564 Predicted intracellular proteins Evidence at protein level CAB033767, HPA050007 Approved Supported Nucleoplasm
Cytosol Ovarian cancer:2.47e-4 (favourable), Head and neck cancer:9.97e-4 (favourable) Expressed in all Expressed in all testis: 210.7 RANGAP1 Fug1, KIAA1835, SD ENSG00000100401 Ran GTPase activating protein 1 22 41245611-41286251 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004293, HPA050110, HPA062034 Supported Validated Nuclear membrane
Vesicles
Cytosol Liver cancer:1.08e-4 (unfavourable), Stomach cancer:5.39e-4 (favourable) Expressed in all Expressed in all testis: 205.5 RANGRF HSPC165, HSPC236, MOG1, RANGNRF ENSG00000108961 RAN guanine nucleotide release factor 17 8288497-8290092 Predicted intracellular proteins Evidence at protein level HPA057280, HPA057888 Approved Supported Nucleoplasm Endometrial cancer:1.65e-4 (favourable), Pancreatic cancer:4.39e-4 (favourable) Expressed in all Expressed in all testis: 71.8 RAP1A KREV-1, SMGP21 ENSG00000116473 RAP1A, member of RAS oncogene family 1 111542218-111716691 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Expressed in all Expressed in all parathyroid gland: 199.7 RAP1B DKFZp586H0723, K-REV, RAL1B ENSG00000127314 RAP1B, member of RAS oncogene family 12 68610839-68671901 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level Renal cancer:8.08e-4 (unfavourable) Expressed in all Expressed in all lymph node: 247.4 RAP1GDS1 SmgGDS ENSG00000138698 RAP1, GTP-GDP dissociation stimulator 1 4 98261384-98443861 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA019060 Approved Supported Cytosol Renal cancer:2.00e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 94.1 RAP2A K-REV, RAP2 ENSG00000125249 RAP2A, member of RAS oncogene family 13 97434222-97469128 Predicted intracellular proteins Evidence at protein level CAB018552 Uncertain Liver cancer:1.55e-4 (unfavourable), Renal cancer:8.06e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 75.1 RAP2C DKFZp313B211 ENSG00000123728 RAP2C, member of RAS oncogene family X 132203024-132219480 Predicted intracellular proteins Evidence at protein level Renal cancer:3.81e-5 (unfavourable) Expressed in all Expressed in all endometrium: 101.9 RAPGEF1 C3G, GRF2 ENSG00000107263 Rap guanine nucleotide exchange factor (GEF) 1 9 131576770-131740074 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006426, HPA075984 Approved Supported Vesicles Renal cancer:1.18e-5 (favourable) Expressed in all Expressed in all placenta: 80.2 RAPGEF2 DKFZP586O1422, KIAA0313, PDZ-GEF1, PDZGEF1, RA-GEF ENSG00000109756 Rap guanine nucleotide exchange factor (GEF) 2 4 159104178-159360169 Predicted intracellular proteins Evidence at protein level HPA057169 Approved Nucleoplasm
Centrosome Renal cancer:1.76e-7 (favourable) Expressed in all Expressed in all thyroid gland: 109.5 RAPH1 ALS2CR18, ALS2CR9, KIAA1681 ENSG00000173166 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 203394345-203535410 Predicted intracellular proteins Evidence at protein level HPA016744, HPA020027 Approved Approved Nuclear bodies
Plasma membrane
Cytosol Mixed Expressed in all thyroid gland: 49.6 RARA NR1B1, RAR ENSG00000131759 Retinoic acid receptor, alpha 17 40309192-40357643 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058282 Supported Nucleus
Cytosol Endometrial cancer:2.60e-4 (favourable) Expressed in all Expressed in all gallbladder: 68.9 RARRES3 HRASLS4, TIG3 ENSG00000133321 Retinoic acid receptor responder (tazarotene induced) 3 11 63536809-63546462 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Pancreatic cancer:6.26e-6 (unfavourable), Breast cancer:1.35e-5 (favourable), Cervical cancer:4.00e-4 (favourable) Expressed in all Expressed in all fallopian tube: 164.2 RARS DALRD1 ENSG00000113643 Arginyl-tRNA synthetase 5 168486445-168519299 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003979, HPA004130 Approved Validated Nucleoplasm
Cytosol Liver cancer:1.10e-8 (unfavourable), Head and neck cancer:7.59e-5 (unfavourable) Expressed in all Expressed in all duodenum: 55.9 RARS2 DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL ENSG00000146282 Arginyl-tRNA synthetase 2, mitochondrial 6 87514378-87590003 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039987, HPA042645 Uncertain Approved Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 56.7 RASA1 CM-AVM, GAP, p120GAP, p120RASGAP, RASA ENSG00000145715 RAS p21 protein activator (GTPase activating protein) 1 5 87267888-87391931 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB007789, HPA036393, HPA064556 Supported Expressed in all Expressed in all placenta: 136.1 RASA4 CAPRI, GAPL, KIAA0538 ENSG00000105808 RAS p21 protein activator 4 7 102573807-102616757 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at transcript level HPA043010 Uncertain Uncertain Vesicles Not detected Expressed in all skeletal muscle: 84.2 RASD1 AGS1, DEXRAS1 ENSG00000108551 RAS, dexamethasone-induced 1 17 17494437-17496395 Predicted intracellular proteins Evidence at protein level HPA047896 Uncertain Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all adipose tissue: 112.9 RASEF FLJ31614, RAB45 ENSG00000165105 RAS and EF-hand domain containing 9 82979585-83063177 Predicted intracellular proteins Evidence at protein level HPA021431 Approved Microtubules Mixed Expressed in all thyroid gland: 44.9 RASSF1 123F2, NORE2A, RDA32, REH3P21 ENSG00000068028 Ras association (RalGDS/AF-6) domain family member 1 3 50329782-50340980 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA040735 Approved Renal cancer:8.58e-5 (unfavourable), Head and neck cancer:2.60e-4 (favourable), Cervical cancer:2.64e-4 (favourable), Liver cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 51.9 RASSF3 ENSG00000153179 Ras association (RalGDS/AF-6) domain family member 3 12 64610513-64697567 Predicted intracellular proteins Evidence at protein level CAB022664, CAB034035, HPA038469 Supported Supported Plasma membrane
Cytosol Expressed in all Expressed in all smooth muscle: 85.0 RASSF4 AD037, MGC44914 ENSG00000107551 Ras association (RalGDS/AF-6) domain family member 4 10 44959407-44995891 Predicted intracellular proteins Evidence at protein level HPA038834 Approved Approved Nucleus
Nucleoli
Cell Junctions Expressed in all Expressed in all cerebral cortex: 71.6 RB1 OSRC, PPP1R130, RB ENSG00000139687 Retinoblastoma 1 13 48303751-48481986 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000095, CAB016687, HPA050082 Supported Validated Nucleoplasm Ovarian cancer:6.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.0 RB1CC1 ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131 ENSG00000023287 RB1-inducible coiled-coil 1 8 52622456-52745843 Predicted intracellular proteins Evidence at protein level HPA024391, HPA053049 Approved Supported Nuclear membrane
Cytosol Endometrial cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all testis: 63.1 RBAK ZNF769 ENSG00000146587 RB-associated KRAB zinc finger 7 5045821-5069488 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071231 Supported Nucleoplasm Expressed in all Expressed in all parathyroid gland: 14.6 RBBP4 lin-53, NURF55, RbAp48 ENSG00000162521 Retinoblastoma binding protein 4 1 32651142-32686211 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB006264, HPA060710, HPA060724 Supported Validated Nucleoplasm Liver cancer:1.89e-6 (unfavourable), Melanoma:6.45e-4 (unfavourable) Expressed in all Expressed in all testis: 138.1 RBBP5 RBQ3, SWD1 ENSG00000117222 Retinoblastoma binding protein 5 1 205086142-205122015 Predicted intracellular proteins Evidence at protein level HPA049042, HPA058085 Uncertain Validated Nucleus
Nucleoli Expressed in all Expressed in all thyroid gland: 16.3 RBBP6 P2P-R, PACT, SNAMA ENSG00000122257 Retinoblastoma binding protein 6 16 24537693-24572863 Predicted intracellular proteins Evidence at protein level CAB032866, HPA041725, HPA043544 Approved Validated Nuclear speckles Expressed in all Expressed in all bone marrow: 91.7 RBBP7 RbAp46 ENSG00000102054 Retinoblastoma binding protein 7 X 16839283-16870414 Predicted intracellular proteins Evidence at protein level CAB037084, HPA060710, HPA060724 Supported Supported Nucleoplasm Thyroid cancer:2.43e-4 (favourable), Liver cancer:5.55e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 377.8 RBBP9 Bog ENSG00000089050 Retinoblastoma binding protein 9 20 18486540-18497243 Predicted intracellular proteins Evidence at protein level HPA015830, HPA049005 Approved Supported Nucleoplasm Expressed in all Expressed in all thyroid gland: 40.6 RBCK1 C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4 ENSG00000125826 RanBP-type and C3HC4-type zinc finger containing 1 20 407498-430966 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024185 Uncertain Renal cancer:7.41e-9 (unfavourable) Expressed in all Expressed in all spleen: 49.1 RBFA C18orf22, FLJ21172, HsT169 ENSG00000101546 Ribosome binding factor A (putative) 18 80034358-80046397 Predicted intracellular proteins Evidence at protein level HPA040485, HPA041479 Approved Supported Mitochondria Liver cancer:2.06e-6 (unfavourable) Expressed in all Expressed in all adipose tissue: 20.3 RBL2 p130, Rb2 ENSG00000103479 Retinoblastoma-like 2 16 53433977-53491649 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016547, HPA019703 Supported Approved Nucleus
Nucleoli
Cytosol Renal cancer:3.57e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 158.3 RBM10 DXS8237E, GPATC9, GPATCH9, KIAA0122, ZRANB5 ENSG00000182872 RNA binding motif protein 10 X 47144869-47186813 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034972, HPA057372 Approved Validated Nuclear speckles Pancreatic cancer:2.86e-6 (favourable), Cervical cancer:6.71e-4 (favourable) Expressed in all Expressed in all ovary: 35.1 RBM12 HRIHFB2091, KIAA0765, SWAN ENSG00000244462 RNA binding motif protein 12 20 35648925-35664956 Predicted intracellular proteins Evidence at protein level HPA043258, HPA043621 Approved Validated Nucleoplasm Liver cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all lymph node: 47.9 RBM12B ENSG00000183808 RNA binding motif protein 12B 8 93729356-93741017 Predicted intracellular proteins Evidence at protein level HPA024398, HPA053050 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 33.1 RBM14 COAA, DKFZp779J0927, SIP, SYTIP1 ENSG00000239306 RNA binding motif protein 14 11 66616582-66627347 Predicted intracellular proteins Evidence at protein level HPA006628 Supported Supported Nuclear speckles Liver cancer:2.02e-7 (unfavourable), Pancreatic cancer:1.04e-4 (favourable) Expressed in all Expressed in all testis: 49.9 RBM15B HUMAGCGB, OTT3 ENSG00000259956 RNA binding motif protein 15B 3 51391268-51397908 Predicted intracellular proteins Evidence at protein level HPA036645, HPA058136 Approved Validated Nucleoplasm Renal cancer:1.84e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.2 RBM17 MGC14439, SPF45 ENSG00000134453 RNA binding motif protein 17 10 6088987-6117457 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037477, HPA037478 Supported Supported Nucleoplasm Liver cancer:4.57e-8 (unfavourable), Renal cancer:4.31e-5 (unfavourable) Expressed in all Expressed in all placenta: 103.9 RBM18 MGC2734 ENSG00000119446 RNA binding motif protein 18 9 122237624-122264839 Predicted intracellular proteins Evidence at protein level HPA057281 Uncertain Approved Nucleus
Nucleoli fibrillar center
Midbody Renal cancer:8.00e-7 (favourable) Expressed in all Expressed in all breast: 20.2 RBM19 DKFZp586F1023, KIAA0682 ENSG00000122965 RNA binding motif protein 19 12 113816738-113966371 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038860, HPA058732 Supported Supported Nucleoli Liver cancer:5.87e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.3 RBM22 Cwc2, FLJ10290, fSAP47, ZC3H16 ENSG00000086589 RNA binding motif protein 22 5 150690794-150701107 Predicted intracellular proteins Evidence at protein level HPA001634 Supported Validated Nucleus Liver cancer:5.50e-6 (unfavourable), Renal cancer:3.58e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 40.3 RBM23 CAPERbeta, FLJ10482, RNPC4 ENSG00000100461 RNA binding motif protein 23 14 22893206-22919184 Predicted intracellular proteins Evidence at protein level HPA004144 Uncertain Approved Nucleoplasm
Intermediate filaments Renal cancer:8.06e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 142.6 RBM25 fSAP94, NET52, RNPC7, S164, Snu71 ENSG00000119707 RNA binding motif protein 25 14 73058436-73123898 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003025, HPA070713 Supported Validated Nuclear speckles Liver cancer:1.42e-4 (unfavourable), Renal cancer:4.26e-4 (unfavourable), Prostate cancer:8.09e-4 (unfavourable) Expressed in all Expressed in all testis: 53.7 RBM26 ARRS2, C13orf10, FLJ20957, PPP1R132, PRO1777, SE70-2, ZC3H17 ENSG00000139746 RNA binding motif protein 26 13 79311824-79406477 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040252 Approved Approved Nuclear speckles Renal cancer:5.87e-6 (unfavourable), Prostate cancer:3.46e-4 (unfavourable), Urothelial cancer:8.20e-4 (favourable) Expressed in all Expressed in all testis: 55.8 RBM27 ARRS1, KIAA1311, Psc1, ZC3H20 ENSG00000091009 RNA binding motif protein 27 5 146203600-146289132 Predicted intracellular proteins Evidence at protein level HPA035944, HPA036422 Approved Approved Nuclear speckles Liver cancer:8.58e-4 (unfavourable) Expressed in all Expressed in all testis: 18.9 RBM28 FLJ10377 ENSG00000106344 RNA binding motif protein 28 7 128297685-128343908 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA019058, HPA026672, HPA031519 Supported Validated Nucleoli Liver cancer:2.72e-11 (unfavourable), Endometrial cancer:2.94e-4 (unfavourable), Melanoma:6.44e-4 (unfavourable) Expressed in all Expressed in all testis: 26.8 RBM3 IS1-RNPL ENSG00000102317 RNA binding motif (RNP1, RRM) protein 3 X 48574449-48579066 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003624, CAB062559 Approved Validated Nucleoplasm Colorectal cancer:3.07e-7 (favourable) Expressed in all Expressed in all breast: 235.9 RBM33 DKFZp434D1319, DKFZp686F102, MGC20460, PRR8 ENSG00000184863 RNA binding motif protein 33 7 155644451-155781485 Predicted intracellular proteins Evidence at protein level HPA019232, HPA021497, HPA021768 Approved Approved Nucleoplasm Head and neck cancer:9.63e-5 (favourable), Renal cancer:1.05e-4 (unfavourable), Urothelial cancer:4.29e-4 (favourable) Expressed in all Expressed in all bone marrow: 40.8 RBM34 KIAA0117 ENSG00000188739 RNA binding motif protein 34 1 235131183-235161457 Predicted intracellular proteins Evidence at protein level HPA028606 Approved Supported Nucleus
Nucleoli Mixed Expressed in all testis: 34.7 RBM38 dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D ENSG00000132819 RNA binding motif protein 38 20 57391407-57409333 Predicted intracellular proteins Evidence at protein level CAB017036 Approved Supported Nucleoplasm
Cytosol Cervical cancer:3.64e-7 (favourable), Renal cancer:1.05e-5 (unfavourable), Thyroid cancer:1.63e-4 (favourable) Expressed in all Expressed in all bone marrow: 86.9 RBM39 CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2 ENSG00000131051 RNA binding motif protein 39 20 35703609-35742312 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001591 Supported Supported Nucleoplasm
Nuclear speckles
Microtubules
Microtubule organizing center Renal cancer:2.78e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 124.6 RBM4 LARK, RBM4A, ZCCHC21, ZCRB3A ENSG00000173933 RNA binding motif protein 4 11 66638617-66666682 Predicted intracellular proteins Evidence at protein level HPA042174, HPA047849 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 136.8 RBM42 MGC10433 ENSG00000126254 RNA binding motif protein 42 19 35629030-35637686 Predicted intracellular proteins Evidence at protein level HPA043671 Supported Approved Nucleus
Cytosol Expressed in all Expressed in all spleen: 39.5 RBM45 DRB1, FLJ44612 ENSG00000155636 RNA binding motif protein 45 2 178112424-178139011 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020448 Approved Supported Nucleus Renal cancer:5.34e-9 (unfavourable), Liver cancer:5.74e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 12.1 RBM48 C7orf64, DKFZp564O0523, HSPC304 ENSG00000127993 RNA binding motif protein 48 7 92528773-92538005 Predicted intracellular proteins Evidence at protein level HPA021777, HPA025306 Uncertain Validated Nucleoplasm Liver cancer:3.17e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 21.8 RBM4B MGC10871, RBM30, RBM4L, ZCCHC15, ZCCHC21B, ZCRB3B ENSG00000173914 RNA binding motif protein 4B 11 66664998-66677921 Predicted intracellular proteins Evidence at protein level HPA042174, HPA047849 Uncertain Uncertain Nucleoplasm
Cytosol Renal cancer:1.02e-4 (unfavourable), Pancreatic cancer:2.10e-4 (favourable), Liver cancer:2.94e-4 (unfavourable) Expressed in all Expressed in all ovary: 36.2 RBM5 H37, LUCA15 ENSG00000003756 RNA binding motif protein 5 3 50088908-50119021 Predicted intracellular proteins Evidence at protein level HPA017335, HPA018011 Approved Validated Nucleoplasm Lung cancer:6.46e-4 (favourable), Pancreatic cancer:7.58e-4 (favourable), Liver cancer:9.77e-4 (unfavourable) Expressed in all Expressed in all endometrium: 112.1 RBM6 3G2, DEF-3, DEF3, g16, NY-LU-12 ENSG00000004534 RNA binding motif protein 6 3 49940007-50100045 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026272, HPA027164 Supported Approved Nuclear speckles
Cytoplasmic bodies Urothelial cancer:5.13e-5 (favourable), Pancreatic cancer:1.41e-4 (favourable), Renal cancer:8.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 82.3 RBM7 ENSG00000076053 RNA binding motif protein 7 11 114400030-114414203 Predicted intracellular proteins Evidence at protein level HPA013993, HPA048003 Supported Validated Nucleoplasm Pancreatic cancer:1.17e-4 (unfavourable), Colorectal cancer:6.14e-4 (favourable) Expressed in all Expressed in all bone marrow: 40.9 RBM8A BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP ENSG00000265241 RNA binding motif protein 8A 1 145917714-145927678 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA018403 Supported Validated Nuclear speckles Prostate cancer:1.55e-4 (unfavourable) Expressed in all Expressed in all esophagus: 162.1 RBMS1 C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1 ENSG00000153250 RNA binding motif, single stranded interacting protein 1 2 160272151-160493794 Predicted intracellular proteins Evidence at protein level HPA047943, HPA061791 Supported Cytosol Renal cancer:1.33e-7 (unfavourable), Liver cancer:4.45e-4 (unfavourable) Expressed in all Expressed in all placenta: 119.0 RBMS2 SCR3 ENSG00000076067 RNA binding motif, single stranded interacting protein 2 12 56521929-56596196 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039225, HPA058784 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Renal cancer:3.22e-4 (favourable) Expressed in all Expressed in all lung: 35.8 RBMX hnRNP-G, HNRNPG, RNMX ENSG00000147274 RNA binding motif protein, X-linked X 136848004-136880764 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA057707 Supported Approved Nucleoplasm Liver cancer:5.16e-6 (unfavourable) Expressed in all Expressed in all ovary: 296.1 RBMX2 CGI-79, Snu17 ENSG00000134597 RNA binding motif protein, X-linked 2 X 130401969-130413343 Predicted intracellular proteins Evidence at protein level HPA026609 Approved Approved Nuclear membrane
Nucleoli Renal cancer:8.44e-9 (unfavourable), Liver cancer:7.04e-4 (unfavourable), Lung cancer:9.15e-4 (favourable) Expressed in all Expressed in all endometrium: 29.2 RBMXL1 KAT3 ENSG00000213516 RNA binding motif protein, X-linked-like 1 1 88979456-88992960 Predicted intracellular proteins Evidence at protein level HPA057707 Supported Approved Nucleoplasm Pancreatic cancer:7.26e-4 (unfavourable), Breast cancer:7.60e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 18.7 RBPJ CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH ENSG00000168214 Recombination signal binding protein for immunoglobulin kappa J region 4 26163455-26435131 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA060647 Supported Nucleoplasm Endometrial cancer:2.98e-4 (favourable) Expressed in all Expressed in all placenta: 76.7 RBSN ZFYVE20 ENSG00000131381 Rabenosyn, RAB effector 3 15070073-15099163 Predicted intracellular proteins Evidence at protein level HPA044878 Approved Validated Vesicles Expressed in all Expressed in all cerebral cortex: 30.8 RBX1 BA554C12.1, RNF75, ROC1 ENSG00000100387 Ring-box 1, E3 ubiquitin protein ligase 22 40951347-40973309 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003038 Uncertain Supported Nucleoplasm Ovarian cancer:6.63e-4 (favourable) Expressed in all Expressed in all epididymis: 69.5 RC3H2 FLJ20301, FLJ20713, MNAB, RNF164 ENSG00000056586 Ring finger and CCCH-type domains 2 9 122844556-122905341 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042863 Approved Supported Cytosol Renal cancer:5.50e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 25.0 RCBTB1 CLLD7, CLLL7, FLJ10716 ENSG00000136144 Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 13 49531946-49585583 Predicted intracellular proteins Evidence at protein level HPA056783 Approved Nucleoplasm Ovarian cancer:1.21e-5 (unfavourable), Lung cancer:5.51e-5 (favourable), Renal cancer:1.75e-4 (favourable) Expressed in all Expressed in all thyroid gland: 73.7 RCBTB2 CHC1L ENSG00000136161 Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 13 48488959-48533256 Predicted intracellular proteins Evidence at protein level HPA040242 Approved Approved Nucleus
Golgi apparatus Renal cancer:2.45e-4 (favourable) Expressed in all Expressed in all thyroid gland: 44.8 RCC1 CHC1 ENSG00000180198 Regulator of chromosome condensation 1 1 28505943-28539300 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015413, HPA027573, HPA027574 Supported Supported Nucleus
Nuclear membrane Renal cancer:2.43e-11 (unfavourable), Liver cancer:1.91e-5 (unfavourable) Expressed in all Expressed in all testis: 63.6 RCHY1 ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363 ENSG00000163743 Ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 4 75479037-75514764 Predicted intracellular proteins Evidence at protein level HPA030339 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.62e-5 (favourable), Urothelial cancer:7.89e-5 (favourable), Colorectal cancer:9.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.5 RCL1 RNAC, RPCL1 ENSG00000120158 RNA terminal phosphate cyclase-like 1 9 4792869-4885917 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA071308 Approved Nucleoplasm Renal cancer:2.40e-7 (favourable), Breast cancer:5.48e-4 (favourable), Liver cancer:8.02e-4 (favourable) Expressed in all Expressed in all liver: 122.9 RCN1 FLJ37041, PIG20, Rcal, RCN ENSG00000049449 Reticulocalbin 1, EF-hand calcium binding domain 11 31812391-32105755 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038474, HPA062104 Approved Validated Endoplasmic reticulum Renal cancer:2.70e-13 (unfavourable), Lung cancer:7.13e-6 (unfavourable) Expressed in all Expressed in all epididymis: 464.4 RCN2 E6BP, ERC-55, ERC55, TCBP49 ENSG00000117906 Reticulocalbin 2, EF-hand calcium binding domain 15 76931619-76954392 Predicted secreted proteins Evidence at protein level HPA030694, HPA030695 Supported Supported Validated Endoplasmic reticulum Liver cancer:7.36e-5 (unfavourable) Expressed in all Expressed in all epididymis: 384.9 RCN3 RLP49 ENSG00000142552 Reticulocalbin 3, EF-hand calcium binding domain 19 49527618-49546962 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043134, HPA050402 Uncertain Approved Endoplasmic reticulum
Vesicles Renal cancer:5.80e-12 (unfavourable) Expressed in all Expressed in all small intestine: 46.0 RCOR1 COREST, KIAA0071, RCOR ENSG00000089902 REST corepressor 1 14 102592661-102730576 Predicted secreted proteins Evidence at protein level CAB001956, HPA049327, HPA054241 Supported Validated Nucleoplasm Urothelial cancer:3.72e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 29.7 RCOR3 FLJ10876 ENSG00000117625 REST corepressor 3 1 211258377-211316385 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007413 Supported Approved Nucleus
Nucleoli Glioma:1.92e-5 (favourable), Lung cancer:5.75e-5 (favourable) Expressed in all Expressed in all testis: 67.1 RDH10 SDR16C4 ENSG00000121039 Retinol dehydrogenase 10 (all-trans) 8 73294612-73325281 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049199 Approved Lipid droplets Expressed in all Expressed in all placenta: 51.3 RDH14 PAN2, SDR7C4 ENSG00000240857 Retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 2 18554723-18560680 Predicted intracellular proteins Evidence at protein level HPA056686 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 31.3 RDX DFNB24 ENSG00000137710 Radixin 11 110174880-110296722 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000263, HPA000763, CAB037312 Supported Validated Plasma membrane Expressed in all Expressed in all adrenal gland: 199.3 RECQL RecQ1, RecQL1 ENSG00000004700 RecQ helicase-like 12 21468911-21501669 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009743, HPA030960, HPA064259 Supported Validated Nucleoplasm Ovarian cancer:3.15e-4 (unfavourable) Expressed in all Expressed in all lymph node: 51.8 RECQL5 FLJ90603, RecQ5 ENSG00000108469 RecQ helicase-like 5 17 75626845-75667189 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029970, HPA029971 Uncertain Supported Nucleus
Cytosol Endometrial cancer:1.73e-6 (unfavourable), Pancreatic cancer:4.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 27.6 REEP3 C10orf74 ENSG00000165476 Receptor accessory protein 3 10 63521363-63625123 Predicted membrane proteins Evidence at protein level Pancreatic cancer:1.32e-4 (unfavourable), Liver cancer:3.19e-4 (unfavourable), Head and neck cancer:7.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 55.8 REEP4 C8orf20, FLJ22246, FLJ22277, PP432 ENSG00000168476 Receptor accessory protein 4 8 22138020-22141951 Predicted membrane proteins Evidence at protein level HPA042683 Approved Approved Cytosol Renal cancer:2.88e-5 (unfavourable), Liver cancer:4.14e-5 (unfavourable) Expressed in all Expressed in all skin: 66.5 REEP5 C5orf18, D5S346, DP1, TB2 ENSG00000129625 Receptor accessory protein 5 5 112876379-112922539 Predicted membrane proteins Evidence at protein level HPA003895, HPA069960 Approved Approved Endoplasmic reticulum Endometrial cancer:5.23e-6 (favourable), Renal cancer:2.05e-5 (favourable) Expressed in all Expressed in all thyroid gland: 341.6 RELA NFKB3, p65 ENSG00000173039 V-rel avian reticuloendotheliosis viral oncogene homolog A 11 65653596-65663094 Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors Evidence at protein level CAB004264, CAB005030, HPA063461 Supported Validated Cytosol Renal cancer:5.66e-4 (unfavourable), Liver cancer:9.18e-4 (unfavourable) Expressed in all Expressed in all endometrium: 62.1 RELB REL-B ENSG00000104856 V-rel avian reticuloendotheliosis viral oncogene homolog B 19 45001430-45038198 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB007753, HPA040506 Approved Supported Nucleoplasm
Cytosol Renal cancer:2.99e-6 (unfavourable), Breast cancer:1.55e-4 (favourable) Expressed in all Expressed in all appendix: 25.8 REPIN1 AP4, H_DJ0584D14.12, RIP60, Zfp464, ZNF464 ENSG00000214022 Replication initiator 1 7 150368189-150374044 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036022 Approved Validated Nucleus Pancreatic cancer:1.12e-4 (favourable), Stomach cancer:1.61e-4 (favourable), Renal cancer:5.56e-4 (favourable), Urothelial cancer:6.41e-4 (favourable) Expressed in all Expressed in all spleen: 49.2 REPS1 ENSG00000135597 RALBP1 associated Eps domain containing 1 6 138903493-138988261 Predicted intracellular proteins Evidence at protein level HPA029961, HPA029962 Approved Approved Vesicles
Plasma membrane
Cytosol Liver cancer:9.47e-4 (unfavourable) Expressed in all Expressed in all testis: 65.9 RER1 ENSG00000157916 Retention in endoplasmic reticulum sorting receptor 1 1 2391775-2405444 Predicted membrane proteins, Transporters Evidence at protein level CAB037240, HPA051400 Supported Validated Golgi apparatus Renal cancer:8.23e-8 (unfavourable) Expressed in all Expressed in all testis: 183.8 RERE ARG, ARP, ATN1L, DNB1, KIAA0458 ENSG00000142599 Arginine-glutamic acid dipeptide (RE) repeats 1 8352397-8817643 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024093 Uncertain Expressed in all Expressed in all endometrium: 93.0 REST NRSF, XBR ENSG00000084093 RE1-silencing transcription factor 4 56907876-56935844 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006079, CAB068222 Supported Approved Nucleoplasm
Cytosol Renal cancer:9.50e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 31.6 RETSAT FLJ20296 ENSG00000042445 Retinol saturase (all-trans-retinol 13,14-reductase) 2 85342088-85354620 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007961, HPA046513 Uncertain Approved Nucleoli Renal cancer:1.95e-10 (favourable), Liver cancer:4.23e-4 (favourable) Expressed in all Expressed in all adipose tissue: 264.9 REV1 REV1L ENSG00000135945 REV1, polymerase (DNA directed) 2 99400475-99490035 Predicted intracellular proteins Evidence at protein level HPA044534, HPA051036 Uncertain Approved Cytosol Prostate cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all endometrium: 22.2 REV3L POLZ, REV3 ENSG00000009413 REV3-like, polymerase (DNA directed), zeta, catalytic subunit 6 111299028-111483715 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064853, HPA069382 Uncertain Approved Nucleoplasm Expressed in all Expressed in all cervix, uterine: 44.3 REXO1 EloA-BP1, KIAA1138, TCEB3BP1 ENSG00000079313 REX1, RNA exonuclease 1 homolog 19 1815246-1848463 Predicted intracellular proteins Evidence at protein level HPA042155, HPA042552 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all testis: 35.5 REXO2 CGI-114, DKFZP566E144, SFN ENSG00000076043 RNA exonuclease 2 11 114439386-114450279 Predicted intracellular proteins Evidence at protein level HPA038450, HPA038451 Supported Supported Nucleoli
Focal adhesion sites
Mitochondria Colorectal cancer:6.51e-4 (favourable), Urothelial cancer:6.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 254.4 REXO4 hPMC2, XPMC2H ENSG00000148300 REX4 homolog, 3'-5' exonuclease 9 133406059-133418096 Predicted intracellular proteins Evidence at protein level HPA047006 Uncertain Supported Nucleus
Nucleoli Liver cancer:4.76e-6 (unfavourable), Renal cancer:2.65e-4 (favourable) Expressed in all Expressed in all testis: 11.3 RFC1 A1, MHCBFB, PO-GA, RFC140 ENSG00000035928 Replication factor C (activator 1) 1, 145kDa 4 39287456-39366375 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009520, HPA046116, HPA069306 Supported Validated Nucleus Colorectal cancer:4.43e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 65.4 RFC2 A1, RFC40 ENSG00000049541 Replication factor C (activator 1) 2, 40kDa 7 74231499-74254458 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029493 Approved Supported Nucleoplasm
Golgi apparatus Renal cancer:2.09e-7 (unfavourable), Liver cancer:6.35e-4 (unfavourable), Cervical cancer:9.91e-4 (favourable) Expressed in all Expressed in all tonsil: 29.3 RFC4 A1, RFC37 ENSG00000163918 Replication factor C (activator 1) 4, 37kDa 3 186789880-186807058 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004557, HPA049123, HPA058507 Supported Validated Nucleoplasm Renal cancer:2.22e-16 (unfavourable), Liver cancer:6.75e-7 (unfavourable), Cervical cancer:7.41e-5 (favourable), Pancreatic cancer:7.38e-4 (unfavourable) Expressed in all Expressed in all testis: 40.5 RFC5 RFC36 ENSG00000111445 Replication factor C (activator 1) 5, 36.5kDa 12 118013588-118033130 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041037 Supported Approved Nucleoplasm Cervical cancer:8.05e-5 (favourable), Renal cancer:2.30e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 22.2 RFFL fring, rififylin, RNF189, RNF34L ENSG00000092871 Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 17 35005990-35089319 Predicted intracellular proteins Evidence at protein level CAB008096, HPA017910, HPA019492 Approved Approved Vesicles Renal cancer:2.43e-5 (unfavourable), Colorectal cancer:4.92e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.9 RFK FLJ11149, RIFK ENSG00000135002 Riboflavin kinase 9 76385517-76394517 Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA023259, CAB033887, HPA057163 Approved Approved Golgi apparatus Expressed in all Expressed in all cerebral cortex: 37.9 RFNG ENSG00000169733 RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 17 82047902-82051831 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011564, HPA031673 Uncertain Supported Nucleus Pancreatic cancer:4.81e-4 (favourable) Expressed in all Expressed in all fallopian tube: 19.4 RFT1 CDG1N ENSG00000163933 RFT1 homolog 3 53088483-53130462 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA060327 Approved Vesicles Liver cancer:1.69e-4 (unfavourable) Expressed in all Expressed in all testis: 25.8 RFWD2 COP1, FLJ10416, RNF200 ENSG00000143207 Ring finger and WD repeat domain 2, E3 ubiquitin protein ligase 1 175944831-176207493 Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.96e-4 (unfavourable) Expressed in all Expressed in all testis: 41.9 RFX1 EF-C ENSG00000132005 Regulatory factor X, 1 (influences HLA class II expression) 19 13961538-14007039 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048722 Approved Supported Nucleoplasm Head and neck cancer:2.42e-4 (favourable), Pancreatic cancer:4.92e-4 (favourable) Expressed in all Expressed in all testis: 16.8 RFX5 ENSG00000143390 Regulatory factor X, 5 (influences HLA class II expression) 1 151340640-151347357 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA018519 Supported Expressed in all Expressed in all lymph node: 86.8 RFXANK ANKRA1, BLS, F14150_1, MGC138628, RFX-B ENSG00000064490 Regulatory factor X-associated ankyrin-containing protein 19 19192229-19201869 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049157, HPA053330 Approved Validated Nucleoplasm Expressed in all Expressed in all fallopian tube: 49.7 RGCC bA157L14.2, C13orf15, RGC-32, RGC32 ENSG00000102760 Regulator of cell cycle 13 41457559-41470882 Predicted secreted proteins Evidence at protein level HPA035638, HPA063701 Approved Supported Nucleus
Nucleoli Colorectal cancer:5.60e-4 (unfavourable) Expressed in all Expressed in all lung: 409.7 RGP1 KIAA0258 ENSG00000107185 RGP1 homolog, RAB6A GEF complex partner 1 9 35749287-35758575 Predicted intracellular proteins Evidence at protein level HPA020414, HPA021085 Approved Validated Plasma membrane
Cytosol Renal cancer:8.55e-13 (favourable), Liver cancer:7.09e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.4 RGPD6 RGP6 ENSG00000183054 RANBP2-like and GRIP domain containing 6 2 110513812-110577185 Predicted intracellular proteins Evidence at protein level HPA045704, HPA049497, HPA051675, HPA067564 Uncertain Uncertain Nuclear membrane
Vesicles Not detected Expressed in all testis: 82.8 RGS10 ENSG00000148908 Regulator of G-protein signaling 10 10 119499828-119542708 Predicted intracellular proteins Evidence at protein level CAB004559, HPA021305, HPA058485 Supported Supported Nucleus
Plasma membrane Renal cancer:4.20e-10 (unfavourable), Endometrial cancer:6.32e-4 (favourable), Cervical cancer:6.81e-4 (favourable) Expressed in all Expressed in all lymph node: 139.8 RGS2 G0S8 ENSG00000116741 Regulator of G-protein signaling 2 1 192809039-192812283 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA013385 Approved Cytosol Renal cancer:2.90e-5 (unfavourable), Breast cancer:2.43e-4 (favourable), Stomach cancer:3.56e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 739.2 RGS3 C2PA, FLJ20370, PDZ-RGS3 ENSG00000138835 Regulator of G-protein signaling 3 9 113444731-113597743 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032507, HPA041109 Validated Nucleoplasm
Mitochondria
Cytosol Liver cancer:6.62e-4 (unfavourable), Breast cancer:9.93e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 66.7 RHBDD1 DKFZp547E052 ENSG00000144468 Rhomboid domain containing 1 2 226835581-226999215 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA013972, HPA057125 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all testis: 32.2 RHBDD2 NPD007, RHBDL7 ENSG00000005486 Rhomboid domain containing 2 7 75842602-75888926 Enzymes, Predicted membrane proteins Evidence at protein level HPA045074, HPA051960 Uncertain Validated Golgi apparatus Renal cancer:8.68e-6 (favourable), Colorectal cancer:3.31e-5 (unfavourable), Glioma:1.25e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 253.1 RHBDF2 FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG ENSG00000129667 Rhomboid 5 homolog 2 (Drosophila) 17 76470891-76501790 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018080 Uncertain Renal cancer:3.96e-11 (unfavourable) Expressed in all Expressed in all appendix: 51.0 RHEB RHEB2 ENSG00000106615 Ras homolog enriched in brain 7 151466012-151520120 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB019436 Uncertain Liver cancer:9.08e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 207.8 RHNO1 C12orf32, HKMT1188, MGC13204, RHINO ENSG00000171792 RAD9-HUS1-RAD1 interacting nuclear orphan 1 12 2876258-2889523 Predicted intracellular proteins Evidence at protein level Renal cancer:5.74e-13 (unfavourable), Liver cancer:2.20e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 28.3 RHOA ARH12, ARHA, Rho12, RhoA, RHOH12 ENSG00000067560 Ras homolog family member A 3 49359145-49412998 Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB005052 Approved Supported Cytosol Renal cancer:3.21e-6 (favourable), Colorectal cancer:3.08e-4 (favourable), Liver cancer:9.15e-4 (unfavourable) Expressed in all Expressed in all lung: 592.9 RHOB ARH6, ARHB, MST081, RhoB, RHOH6 ENSG00000143878 Ras homolog family member B 2 20447074-20449445 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.23e-4 (favourable) Expressed in all Expressed in all adrenal gland: 714.3 RHOBTB3 KIAA0878 ENSG00000164292 Rho-related BTB domain containing 3 5 95713522-95824383 Predicted intracellular proteins Evidence at protein level HPA000265 Uncertain Vesicles Expressed in all Expressed in all ovary: 98.7 RHOC ARH9, ARHC, RhoC ENSG00000155366 Ras homolog family member C 1 112701106-112707434 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA051461 Uncertain Renal cancer:3.65e-5 (unfavourable), Liver cancer:2.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 685.6 RHOF ARHF, FLJ20247, RIF ENSG00000139725 Ras homolog family member F (in filopodia) 12 121777754-121803403 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045912 Uncertain Nucleus
Golgi apparatus Mixed Expressed in all lymph node: 46.8 RHOG ARHG, MGC125835, MGC125836, RhoG ENSG00000177105 Ras homolog family member G 11 3826978-3840983 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039871 Supported Renal cancer:9.49e-8 (unfavourable), Colorectal cancer:1.81e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 170.8 RHOQ ARHQ, RASL7A, TC10 ENSG00000119729 Ras homolog family member Q 2 46541806-46583121 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044938 Approved Vesicles
Cytosol Liver cancer:9.60e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 169.1 RHOT1 ARHT1, FLJ11040, MIRO-1 ENSG00000126858 Ras homolog family member T1 17 32142454-32253374 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010687, CAB068223, CAB068224 Supported Expressed in all Expressed in all parathyroid gland: 47.9 RHOT2 ARHT2, C16orf39, MIRO-2 ENSG00000140983 Ras homolog family member T2 16 668086-674174 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012624, HPA012895 Approved Supported Cytosol Head and neck cancer:5.01e-4 (favourable), Renal cancer:5.43e-4 (favourable) Expressed in all Expressed in all spleen: 31.7 RHOU ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1 ENSG00000116574 Ras homolog family member U 1 228735077-228746669 Predicted intracellular proteins Evidence at protein level HPA049592 Approved Renal cancer:3.56e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 62.3 RIC1 bA207C16.1, KIAA1432 ENSG00000107036 RIC1 homolog, RAB6A GEF complex partner 1 9 5629025-5776557 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051578 Supported Expressed in all Expressed in all parathyroid gland: 22.1 RIC8A synembryn, synembryn-A ENSG00000177963 RIC8 guanine nucleotide exchange factor A 11 207511-215113 Predicted intracellular proteins Evidence at protein level HPA041491, CAB046012 Approved Supported Cytosol Liver cancer:1.11e-6 (unfavourable), Endometrial cancer:8.60e-4 (favourable) Expressed in all Expressed in all smooth muscle: 71.5 RICTOR AVO3, KIAA1999, MGC39830, PIA ENSG00000164327 RPTOR independent companion of MTOR, complex 2 5 38937919-39074408 Predicted intracellular proteins Evidence at protein level HPA037802, HPA037803 Approved Approved Mitochondria Expressed in all Expressed in all testis: 17.2 RIF1 FLJ10599, FLJ12870 ENSG00000080345 Replication timing regulatory factor 1 2 151409883-151508013 Predicted intracellular proteins Evidence at protein level HPA036887, HPA036888 Supported Uncertain Nucleus
Nuclear bodies
Plasma membrane Expressed in all Expressed in all testis: 21.1 RIMKLB FAM80B, KIAA1238, NAAGS, NAAGS-I ENSG00000166532 Ribosomal modification protein rimK-like family member B 12 8681600-8783095 Enzymes, Predicted intracellular proteins Evidence at protein level HPA059552 Approved Nucleoplasm
Microtubule organizing center Mixed Expressed in all endometrium: 74.3 RIN2 RASSF4 ENSG00000132669 Ras and Rab interactor 2 20 19886521-20002457 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA034641 Approved Approved Nucleoli
Golgi apparatus
Cytosol Renal cancer:8.34e-6 (favourable) Expressed in all Expressed in all gallbladder: 29.0 RINT1 FLJ11785, RINT-1 ENSG00000135249 RAD50 interactor 1 7 105532085-105567677 Predicted intracellular proteins Evidence at protein level HPA019875, HPA031646 Approved Approved Golgi apparatus Thyroid cancer:2.39e-5 (unfavourable) Expressed in all Expressed in all testis: 18.9 RIOK1 AD034, bA288G3.1, FLJ30006, RRP10 ENSG00000124784 RIO kinase 1 6 7389496-7418037 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017866, HPA051446 Supported Approved Nucleoli
Nuclear speckles
Cytosol Liver cancer:3.41e-5 (unfavourable), Renal cancer:5.85e-5 (unfavourable), Melanoma:4.43e-4 (unfavourable) Expressed in all Expressed in all testis: 29.5 RIOK2 FLJ11159 ENSG00000058729 RIO kinase 2 5 97160867-97183260 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005681 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all testis: 22.0 RIOK3 SUDD ENSG00000101782 RIO kinase 3 18 23452823-23486603 Enzymes, Predicted intracellular proteins Evidence at protein level HPA001620, HPA024184 Approved Approved Golgi apparatus
Plasma membrane
Microtubule organizing center
Cytosol Pancreatic cancer:4.10e-4 (unfavourable), Prostate cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 75.0 RIPK1 RIP ENSG00000137275 Receptor (TNFRSF)-interacting serine-threonine kinase 1 6 3063991-3115187 Enzymes, Predicted intracellular proteins Evidence at protein level CAB010302, HPA015257 Supported Validated Plasma membrane
Cytosol Urothelial cancer:6.71e-4 (favourable) Expressed in all Expressed in all skin: 26.1 RIT1 MGC125864, MGC125865, RIBB, RIT, ROC1 ENSG00000143622 Ras-like without CAAX 1 1 155897808-155911404 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053249 Approved Liver cancer:8.64e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 50.6 RITA1 C12orf52, FLJ14827, RITA ENSG00000139405 RBPJ interacting and tubulin associated 1 12 113185526-113192368 Predicted intracellular proteins Evidence at protein level HPA039094, HPA039095, HPA061531 Supported Supported Nucleus Liver cancer:9.79e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 20.2 RLF Zn-15L, ZNF292L ENSG00000117000 Rearranged L-myc fusion 1 40161373-40240921 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054653, HPA057300 Uncertain Approved Nucleus Renal cancer:7.68e-6 (unfavourable), Liver cancer:1.75e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 20.8 RLIM MGC15161, NY-REN-43, RNF12 ENSG00000131263 Ring finger protein, LIM domain interacting X 74585217-74614617 Predicted intracellular proteins Evidence at protein level HPA018895 Approved Supported Nucleoplasm
Cytosol Thyroid cancer:6.04e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 29.1 RMDN1 CGI-90, FAM82B, FLJ20665, RMD1 ENSG00000176623 Regulator of microtubule dynamics 1 8 86468257-86514357 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA026495 Approved Supported Centrosome Renal cancer:8.51e-4 (favourable) Expressed in all Expressed in all thyroid gland: 83.9 RMDN2 FAM82A, FAM82A1, FLJ32954, RMD2 ENSG00000115841 Regulator of microtubule dynamics 2 2 37923187-38067142 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034705, HPA034706 Approved Supported Cytosol Lung cancer:2.63e-4 (favourable) Mixed Expressed in all adrenal gland: 69.2 RMDN3 FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3 ENSG00000137824 Regulator of microtubule dynamics 3 15 40735884-40755851 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009975 Supported Validated Mitochondria Renal cancer:6.70e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 58.3 RMI1 BLAP75, C9orf76, FLJ12888 ENSG00000178966 RecQ mediated genome instability 1 9 83980711-84004074 Predicted intracellular proteins Evidence at protein level HPA021661 Supported Nucleoplasm
Nuclear bodies Liver cancer:8.71e-4 (unfavourable) Expressed in all Expressed in all testis: 21.0 RMND1 bA351K16.3, C6orf96, FLJ20627, RMD1 ENSG00000155906 Required for meiotic nuclear division 1 homolog 6 151404763-151452181 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA031397, HPA031398, HPA031399 Approved Supported Mitochondria Head and neck cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all kidney: 43.8 RMND5A FLJ13910, GID2, GID2A, p44CTLH, RMD5 ENSG00000153561 Required for meiotic nuclear division 5 homolog A 2 86720173-86778041 Predicted intracellular proteins Evidence at protein level HPA046795, HPA060843 Uncertain Approved Nucleoplasm Endometrial cancer:3.03e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 38.5 RMND5B FLJ22318, GID2, GID2B ENSG00000145916 Required for meiotic nuclear division 5 homolog B 5 178130996-178150565 Predicted intracellular proteins Evidence at protein level HPA047778 Uncertain Approved Nucleoplasm Renal cancer:7.22e-8 (favourable), Pancreatic cancer:7.66e-4 (favourable) Expressed in all Expressed in all testis: 94.4 RNASE1 RAC1, RNS1 ENSG00000129538 Ribonuclease, RNase A family, 1 (pancreatic) 14 20801228-20803278 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001140 Supported Approved Nucleoplasm
Vesicles Expressed in all Expressed in all pancreas: 1947.0 RNASEH1 ENSG00000171865 Ribonuclease H1 2 3544793-3558616 Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA043037 Uncertain Liver cancer:7.83e-6 (unfavourable) Expressed in all Expressed in all smooth muscle: 10.9 RNASEH2A AGS4, RNASEHI, RNHIA, RNHL ENSG00000104889 Ribonuclease H2, subunit A 19 12806580-12813638 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042692 Validated Nucleus
Cytosol Renal cancer:6.29e-6 (unfavourable), Liver cancer:8.72e-5 (unfavourable), Cervical cancer:1.18e-4 (favourable), Ovarian cancer:1.22e-4 (favourable), Colorectal cancer:6.18e-4 (favourable) Expressed in all Expressed in all testis: 21.6 RNASEH2B AGS2, DLEU8, FLJ11712 ENSG00000136104 Ribonuclease H2, subunit B 13 50909678-50973745 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040084, HPA041469 Approved Validated Nucleus Renal cancer:2.54e-8 (unfavourable) Expressed in all Expressed in all lymph node: 27.4 RNASEH2C AGS3, AYP1 ENSG00000172922 Ribonuclease H2, subunit C 11 65714896-65720947 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065375 Approved Nucleus Pancreatic cancer:3.68e-5 (favourable), Renal cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.1 RNASEK MGC71993 ENSG00000219200 Ribonuclease, RNase K 17 7012417-7014532 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA044708 Uncertain Pancreatic cancer:1.92e-4 (favourable) Expressed in all Expressed in all adrenal gland: 470.3 RNASET2 bA514O12.3, FLJ10907, RNASE6PL ENSG00000026297 Ribonuclease T2 6 166929504-166957191 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029013, HPA066509 Approved Renal cancer:1.70e-14 (unfavourable) Expressed in all Expressed in all spleen: 284.2 RNF10 KIAA0262, RIE2 ENSG00000022840 Ring finger protein 10 12 120533480-120577594 Predicted intracellular proteins Evidence at protein level HPA052643 Approved Approved Nucleoplasm
Mitochondria Liver cancer:5.30e-5 (unfavourable) Expressed in all Expressed in all testis: 178.9 RNF103 hkf-1, KF1, ZFP103 ENSG00000239305 Ring finger protein 103 2 86603393-86623866 Predicted membrane proteins Evidence at protein level HPA057922 Approved Urothelial cancer:6.77e-5 (favourable) Expressed in all Expressed in all epididymis: 54.2 RNF11 CGI-123, MGC51169, Sid1669p ENSG00000123091 Ring finger protein 11 1 51236271-51273455 Predicted intracellular proteins Evidence at protein level HPA045781 Uncertain Renal cancer:3.14e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 151.9 RNF111 ARK, Arkadia, DKFZP761D081, FLJ38008 ENSG00000157450 Ring finger protein 111 15 58865175-59097419 Predicted intracellular proteins Evidence at protein level HPA038576, HPA038577 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 22.4 RNF113A Cwc24, RNF113, ZNF183 ENSG00000125352 Ring finger protein 113A X 119870475-119871827 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA000160 Approved Urothelial cancer:6.23e-4 (favourable), Renal cancer:7.93e-4 (unfavourable) Expressed in all Expressed in all lymph node: 24.9 RNF114 PSORS12, ZNF313 ENSG00000124226 Ring finger protein 114 20 49936336-49953892 Predicted intracellular proteins Evidence at protein level HPA021184 Approved Supported Plasma membrane
Cytosol Endometrial cancer:8.10e-6 (unfavourable), Thyroid cancer:3.01e-4 (favourable), Liver cancer:3.11e-4 (unfavourable) Expressed in all Expressed in all testis: 149.3 RNF121 FLJ11099 ENSG00000137522 Ring finger protein 121 11 71928701-71997597 Predicted membrane proteins Evidence at protein level HPA046041 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Renal cancer:2.72e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 27.9 RNF122 FLJ12526 ENSG00000133874 Ring finger protein 122 8 33547755-33567125 Predicted membrane proteins Evidence at transcript level HPA003888 Uncertain Renal cancer:4.50e-7 (unfavourable), Thyroid cancer:1.88e-4 (unfavourable), Prostate cancer:5.37e-4 (favourable) Expressed in all Expressed in all fallopian tube: 21.4 RNF123 FLJ12565 ENSG00000164068 Ring finger protein 123 3 49689499-49721529 Predicted intracellular proteins Evidence at protein level HPA065983, HPA071879 Approved Approved Cytosol Renal cancer:1.33e-8 (favourable) Expressed in all Expressed in all skeletal muscle: 53.3 RNF126 FLJ20552 ENSG00000070423 Ring finger protein 126 19 647526-663277 Predicted intracellular proteins Evidence at protein level HPA043050 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 38.3 RNF13 RZF ENSG00000082996 Ring finger protein 13 3 149812708-149962139 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA064784 Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:2.00e-8 (favourable) Expressed in all Expressed in all thyroid gland: 94.0 RNF130 G1RZFP, GOLIATH, GP ENSG00000113269 Ring finger protein 130 5 179911651-180072118 Predicted membrane proteins Evidence at protein level HPA014499 Approved Cervical cancer:6.32e-4 (favourable) Expressed in all Expressed in all adipose tissue: 74.3 RNF135 MGC13061 ENSG00000181481 Ring finger protein 135 17 30968785-30999911 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021576, HPA052404 Approved Approved Vesicles Renal cancer:7.51e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.1 RNF138 NARF, STRIN ENSG00000134758 Ring finger protein 138, E3 ubiquitin protein ligase 18 32091855-32131561 Predicted intracellular proteins Evidence at protein level HPA041101 Approved Mitochondria Expressed in all Expressed in all testis: 166.5 RNF139 HRCA1, RCA1, TRC8 ENSG00000170881 Ring finger protein 139 8 124474738-124487914 Disease related genes, Predicted membrane proteins Evidence at protein level HPA001202 Approved Pancreatic cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all testis: 114.1 RNF14 ARA54, HFB30, TRIAD2 ENSG00000013561 Ring finger protein 14 5 141958328-141990291 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008716 Approved Supported Cytosol Renal cancer:1.71e-4 (favourable), Thyroid cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all testis: 136.4 RNF141 ZFP26, ZNF230 ENSG00000110315 Ring finger protein 141 11 10511678-10541230 Predicted intracellular proteins Evidence at protein level HPA018133 Approved Approved Nucleoplasm
Microtubules Pancreatic cancer:1.14e-4 (unfavourable), Renal cancer:2.60e-4 (favourable) Expressed in all Expressed in all testis: 129.5 RNF145 FLJ31951 ENSG00000145860 Ring finger protein 145 5 159157409-159210053 Predicted membrane proteins Evidence at protein level HPA036562 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:1.64e-6 (unfavourable) Expressed in all Expressed in all lung: 109.1 RNF146 dactylidin, dJ351K20.1, DKFZp434O1427 ENSG00000118518 Ring finger protein 146 6 127266610-127288567 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027158, HPA027209 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:5.26e-5 (favourable), Renal cancer:7.32e-4 (favourable) Expressed in all Expressed in all endometrium: 94.0 RNF149 FLJ90504 ENSG00000163162 Ring finger protein 149 2 101271219-101308701 Predicted membrane proteins Evidence at protein level HPA011424 Approved Approved Vesicles
Plasma membrane Renal cancer:2.04e-8 (unfavourable), Urothelial cancer:2.91e-4 (favourable) Expressed in all Expressed in all appendix: 69.4 RNF166 MGC14381, MGC2647 ENSG00000158717 Ring finger protein 166 16 88696495-88706421 Predicted intracellular proteins Evidence at protein level HPA042970 Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:9.45e-6 (unfavourable), Pancreatic cancer:1.04e-4 (favourable) Expressed in all Expressed in all bone marrow: 57.2 RNF167 DKFZP566H073 ENSG00000108523 Ring finger protein 167 17 4940008-4945222 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA049810 Approved Approved Cytosol Pancreatic cancer:2.03e-6 (favourable), Renal cancer:4.47e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 114.7 RNF170 ADSA, DKFZP564A022, SNAX1 ENSG00000120925 Ring finger protein 170 8 42849637-42897290 Disease related genes, Predicted membrane proteins Evidence at protein level HPA050931, HPA054621 Uncertain Expressed in all Expressed in all thyroid gland: 47.6 RNF181 HSPC238 ENSG00000168894 Ring finger protein 181 2 85595725-85597613 Predicted intracellular proteins Evidence at protein level HPA046112, HPA062121 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.06e-6 (unfavourable), Thyroid cancer:4.59e-5 (favourable) Expressed in all Expressed in all thyroid gland: 171.1 RNF185 FLJ38628 ENSG00000138942 Ring finger protein 185 22 31160183-31207019 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:4.82e-5 (favourable) Expressed in all Expressed in all thyroid gland: 86.4 RNF187 ENSG00000168159 Ring finger protein 187 1 228487061-228495766 Predicted intracellular proteins Evidence at protein level HPA030098 Approved Supported Nucleoplasm
Cytosol Colorectal cancer:2.83e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 109.4 RNF19A DKFZp566B1346, dorfin, RNF19 ENSG00000034677 Ring finger protein 19A, RBR E3 ubiquitin protein ligase 8 100257059-100410015 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB011455, HPA023652 Approved Urothelial cancer:3.28e-5 (favourable), Renal cancer:7.99e-5 (unfavourable) Expressed in all Expressed in all testis: 98.8 RNF19B FLJ90005, IBRDC3 ENSG00000116514 Ring finger protein 19B 1 32936445-32964685 Predicted membrane proteins Evidence at protein level HPA049587 Approved Approved Cytosol Liver cancer:5.41e-6 (unfavourable), Renal cancer:4.39e-5 (favourable), Head and neck cancer:3.39e-4 (favourable) Expressed in all Expressed in all testis: 154.8 RNF2 BAP-1, BAP1, DING, HIPI3, RING1B, RING2 ENSG00000121481 Ring finger protein 2 1 185045364-185102608 Predicted intracellular proteins Evidence at protein level HPA026803 Uncertain Validated Nucleoplasm
Nuclear bodies Renal cancer:1.94e-7 (unfavourable), Liver cancer:1.08e-5 (unfavourable) Expressed in all Expressed in all testis: 42.0 RNF20 BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779 ENSG00000155827 Ring finger protein 20, E3 ubiquitin protein ligase 9 101533851-101563344 Predicted intracellular proteins Evidence at protein level CAB012478, HPA051773 Supported Validated Nucleoplasm Renal cancer:1.64e-6 (favourable) Expressed in all Expressed in all testis: 59.0 RNF213 C17orf27, KIAA1554, KIAA1618, MYMY2, NET57 ENSG00000173821 Ring finger protein 213 17 80260866-80398786 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003347, HPA026790 Approved Supported Cytosol Endometrial cancer:4.65e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 66.8 RNF214 DKFZp547C195 ENSG00000167257 Ring finger protein 214 11 117232625-117286445 Predicted intracellular proteins Evidence at protein level HPA039332 Approved Approved Golgi apparatus
Cytosol Liver cancer:6.03e-5 (unfavourable) Expressed in all Expressed in all testis: 33.1 RNF215 ENSG00000099999 Ring finger protein 215 22 30368811-30421771 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019262, HPA056498 Approved Approved Nucleoli
Microtubules Renal cancer:6.37e-10 (unfavourable) Expressed in all Expressed in all cerebral cortex: 19.3 RNF216 TRIAD3, UBCE7IP1, ZIN ENSG00000011275 Ring finger protein 216 7 5620047-5781739 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018955, HPA021123 Supported Supported Nucleoplasm
Cytosol Pancreatic cancer:6.24e-5 (favourable), Liver cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all testis: 49.9 RNF220 C1orf164, FLJ10597 ENSG00000187147 Ring finger protein 220 1 44405194-44651724 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA027577, HPA027578 Uncertain Approved Nucleus Liver cancer:2.35e-6 (unfavourable), Renal cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 48.0 RNF25 AO7, FLJ13906 ENSG00000163481 Ring finger protein 25 2 218663864-218672411 Predicted intracellular proteins Evidence at protein level HPA036420, HPA036421 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:6.58e-4 (unfavourable) Expressed in all Expressed in all testis: 14.5 RNF26 MGC2642 ENSG00000173456 Ring finger protein 26 11 119334527-119337313 Predicted membrane proteins Evidence at transcript level HPA027620 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:3.45e-6 (favourable), Liver cancer:3.19e-4 (unfavourable), Urothelial cancer:7.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.3 RNF31 FLJ10111, FLJ23501, HOIP, ZIBRA ENSG00000092098 Ring finger protein 31 14 24146683-24160661 Predicted intracellular proteins Evidence at protein level CAB009063, HPA048745 Approved Approved Cytosol Expressed in all Expressed in all skin: 44.4 RNF34 FLJ21786, RIF, RIFF ENSG00000170633 Ring finger protein 34, E3 ubiquitin protein ligase 12 121400041-121430623 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA074151 Supported Nucleoplasm
Nuclear bodies Liver cancer:6.72e-8 (unfavourable), Urothelial cancer:3.02e-4 (favourable), Renal cancer:4.63e-4 (unfavourable) Expressed in all Expressed in all testis: 45.8 RNF38 ENSG00000137075 Ring finger protein 38 9 36336396-36487548 Predicted intracellular proteins Evidence at protein level HPA015853 Approved Supported Nucleoplasm Renal cancer:2.90e-6 (favourable) Expressed in all Expressed in all testis: 116.2 RNF4 RES4-26, SLX5, SNURF ENSG00000063978 Ring finger protein 4 4 2462220-2625320 Predicted intracellular proteins Evidence at protein level HPA049356 Approved Lung cancer:6.38e-4 (unfavourable) Expressed in all Expressed in all testis: 56.5 RNF40 BRE1B, KIAA0661, RBP95, STARING ENSG00000103549 Ring finger protein 40, E3 ubiquitin protein ligase 16 30761745-30776307 Predicted intracellular proteins Evidence at protein level HPA041330, HPA054227 Approved Validated Nucleoplasm Renal cancer:8.11e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 77.4 RNF41 NRDP1, SBBI03 ENSG00000181852 Ring finger protein 41, E3 ubiquitin protein ligase 12 56202175-56221933 Predicted intracellular proteins Evidence at protein level HPA016812 Approved Approved Nucleus
Nuclear bodies
Midbody ring Renal cancer:2.52e-5 (favourable), Liver cancer:6.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 54.8 RNF44 KIAA1100 ENSG00000146083 Ring finger protein 44 5 176526697-176538025 Predicted intracellular proteins Evidence at protein level HPA038981 Uncertain Approved Nucleoplasm Endometrial cancer:2.57e-7 (unfavourable), Liver cancer:8.45e-4 (unfavourable) Expressed in all Expressed in all spleen: 51.0 RNF6 DKFZp686P0776 ENSG00000127870 Ring finger protein (C3H2C3 type) 6 13 26132115-26222493 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039343, HPA040048 Approved Supported Nuclear membrane Cervical cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all testis: 60.8 RNF7 CKBBP1, ROC2, SAG ENSG00000114125 Ring finger protein 7 3 141738204-141747560 Predicted intracellular proteins Evidence at protein level HPA036995 Approved Supported Nucleoplasm Renal cancer:1.54e-9 (unfavourable), Liver cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 84.7 RNH1 RAI, RNH ENSG00000023191 Ribonuclease/angiogenin inhibitor 1 11 494512-507300 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039223, HPA040781 Approved Validated Nucleoplasm
Cytosol Renal cancer:2.14e-5 (favourable) Expressed in all Expressed in all skin: 73.2 RNLS C10orf59, FLJ11218, renalase ENSG00000184719 Renalase, FAD-dependent amine oxidase 10 88273864-88584530 Enzymes, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all kidney: 26.6 RNMT RG7MT1 ENSG00000101654 RNA (guanine-7-) methyltransferase 18 13726660-13764558 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039409 Approved Validated Nucleoplasm
Nucleoli fibrillar center Expressed in all Expressed in all testis: 30.8 RNMTL1 FLJ10581, HC90, MRM3, RMTL1 ENSG00000171861 RNA methyltransferase like 1 17 782273-792509 Predicted intracellular proteins Evidence at protein level HPA022534, HPA023031, HPA023292 Supported Supported Mitochondria Endometrial cancer:2.81e-4 (favourable), Renal cancer:3.00e-4 (favourable) Expressed in all Expressed in all testis: 31.5 RNPC3 FLJ20008, KIAA1839, RBM40, SNRNP65 ENSG00000185946 RNA-binding region (RNP1, RRM) containing 3 1 103525691-103555239 Predicted intracellular proteins Evidence at protein level HPA052434 Supported Nucleoplasm Lung cancer:1.53e-4 (favourable), Urothelial cancer:5.25e-4 (favourable), Prostate cancer:7.70e-4 (unfavourable), Pancreatic cancer:7.82e-4 (favourable) Expressed in all Expressed in all epididymis: 65.9 RNPEP ENSG00000176393 Arginyl aminopeptidase (aminopeptidase B) 1 201982372-202006147 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA036074, HPA036075, HPA061487 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all duodenum: 68.3 RNPEPL1 ENSG00000142327 Arginyl aminopeptidase (aminopeptidase B)-like 1 2 240565804-240581372 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036772 Uncertain Approved Nucleus
Nucleoli Liver cancer:5.06e-4 (unfavourable), Head and neck cancer:7.43e-4 (favourable) Expressed in all Expressed in all skin: 29.4 RNPS1 ENSG00000205937 RNA binding protein S1, serine-rich domain 16 2253116-2268412 Predicted intracellular proteins, Transporters Evidence at protein level HPA044014 Approved Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 144.2 ROCK2 ENSG00000134318 Rho-associated, coiled-coil containing protein kinase 2 2 11179761-11348330 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007459, CAB008666, HPA044109 Approved Supported Cytosol Renal cancer:1.57e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 40.7 ROGDI FLJ22386 ENSG00000067836 Rogdi homolog 16 4796968-4802950 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041000 Uncertain Renal cancer:2.67e-5 (favourable), Pancreatic cancer:9.71e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 39.3 ROMO1 bA353C18.2, C20orf52, MTGMP ENSG00000125995 Reactive oxygen species modulator 1 20 35699272-35700984 Predicted intracellular proteins, Transporters Evidence at protein level HPA012782 Uncertain Expressed in all Expressed in all adrenal gland: 121.3 RORA NR1F1, ROR1, ROR2, ROR3, RZRA ENSG00000069667 RAR-related orphan receptor A 15 60488284-61229319 Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009861 Approved Renal cancer:5.42e-6 (favourable) Mixed Expressed in all skin: 76.4 RP11-1212A22.4 ENSG00000233024 16 18358086-18379331 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Uncertain Nucleoplasm Not detected Expressed in all parathyroid gland: 129.0 RP11-231C14.4 ENSG00000169203 16 29483642-29505999 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053611 Approved Uncertain Nucleoplasm Not detected Expressed in all skin: 135.7 RP11-343C2.11 ENSG00000260914 16 69299682-69322700 Predicted intracellular proteins Evidence at protein level HPA060092 Uncertain Midbody Not detected Expressed in all cerebral cortex: 85.5 RP11-345J4.5 ENSG00000261740 16 29443230-29454651 Predicted intracellular proteins Evidence at transcript level Expressed in all Expressed in all lymph node: 18.0 RP11-437B10.1 ENSG00000279765 15 92883413-92949230 Predicted intracellular proteins Evidence at transcript level Not detected Expressed in all bone marrow: 244.2 RP11-468E2.1 ENSG00000254692 14 24189157-24213473 Predicted membrane proteins Evidence at protein level HPA059249 Approved Approved Golgi apparatus Not detected Expressed in all parathyroid gland: 53.3 RP11-80H18.3 ENSG00000255154 Hydroxyacyl-thioester dehydratase type 2, mitochondrial 3 58306262-58318574 Predicted intracellular proteins Evidence at protein level HPA066812 Supported Nucleoli
Mitochondria Not detected Expressed in all thyroid gland: 14.6 RP9 PAP-1 ENSG00000164610 Retinitis pigmentosa 9 (autosomal dominant) 7 33094797-33109401 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031523, HPA050778 Uncertain Supported Nucleus
Cytosol Renal cancer:2.65e-5 (unfavourable), Liver cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all testis: 29.2 RPA1 HSSB, REPA1, RF-A, RP-A, RPA70 ENSG00000132383 Replication protein A1, 70kDa 17 1829702-1900082 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004563, HPA006914, HPA046497 Supported Validated Nucleoplasm Liver cancer:9.00e-9 (unfavourable) Expressed in all Expressed in all fallopian tube: 44.3 RPA2 ENSG00000117748 Replication protein A2, 32kDa 1 27891524-27914746 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016538, HPA026306, HPA026309 Supported Validated Nucleoplasm
Nuclear bodies Cervical cancer:4.33e-4 (favourable), Head and neck cancer:8.12e-4 (favourable) Expressed in all Expressed in all testis: 103.3 RPA3 REPA3 ENSG00000106399 Replication protein A3, 14kDa 7 7636518-7718607 Predicted intracellular proteins Evidence at protein level HPA005708 Approved Liver cancer:5.16e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 50.6 RPAIN hRIP, MGC4189, RIP ENSG00000129197 RPA interacting protein 17 5419641-5432876 Predicted intracellular proteins Evidence at protein level HPA023924, HPA031526 Approved Approved Nucleus
Nucleoli fibrillar center Prostate cancer:4.41e-5 (unfavourable), Pancreatic cancer:5.20e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 26.7 RPAP1 DKFZP727M111, FLJ12732, KIAA1403, MGC858 ENSG00000103932 RNA polymerase II associated protein 1 15 41517176-41544269 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041739 Approved Approved Nucleoplasm
Cytosol Thyroid cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 13.1 RPAP3 FLJ21908, spag ENSG00000005175 RNA polymerase II associated protein 3 12 47661249-47706061 Predicted intracellular proteins Evidence at protein level HPA038311, HPA038312 Approved Approved Cytosol Liver cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all lymph node: 34.9 RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase 2 210002565-210022259 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036498, HPA036499 Approved Liver cancer:1.42e-6 (unfavourable), Pancreatic cancer:7.00e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.3 RPF1 BXDC5 ENSG00000117133 Ribosome production factor 1 homolog 1 84479259-84497790 Predicted intracellular proteins Evidence at protein level HPA024642 Supported Validated Nucleoli Liver cancer:1.60e-5 (unfavourable) Expressed in all Expressed in all testis: 58.5 RPF2 bA397G5.4, BXDC1, FLJ21087 ENSG00000197498 Ribosome production factor 2 homolog 6 110982015-111028263 Predicted intracellular proteins Evidence at protein level HPA035475 Supported Supported Nucleus
Nucleoli Renal cancer:2.07e-6 (unfavourable), Head and neck cancer:2.04e-4 (unfavourable), Liver cancer:2.25e-4 (unfavourable) Expressed in all Expressed in all testis: 28.0 RPGR COD1, CORDX1, CRD, RP15, RP3 ENSG00000156313 Retinitis pigmentosa GTPase regulator X 38269163-38327564 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001593, HPA073455 Uncertain Supported Golgi apparatus Expressed in all Expressed in all fallopian tube: 23.0 RPIA ENSG00000153574 Ribose 5-phosphate isomerase A 2 88691644-88750935 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042620, HPA057954 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Renal cancer:8.53e-6 (unfavourable), Liver cancer:1.46e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 54.3 RPL10 DXS648, DXS648E, FLJ23544, L10, NOV, QM ENSG00000147403 Ribosomal protein L10 X 154389955-154409168 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB010339, HPA011311 Supported Validated Endoplasmic reticulum
Cytosol Renal cancer:7.67e-6 (unfavourable) Expressed in all Expressed in all ovary: 9655.2 RPL10A Csa-19, L10A, NEDD6 ENSG00000198755 Ribosomal protein L10a 6 35468408-35470785 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA053803 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:3.77e-4 (unfavourable) Expressed in all Expressed in all ovary: 3913.5 RPL11 L11 ENSG00000142676 Ribosomal protein L11 1 23691779-23696425 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA002734, HPA074839 Approved Approved Vesicles Renal cancer:5.93e-6 (unfavourable), Breast cancer:2.55e-4 (favourable) Expressed in all Expressed in all ovary: 4915.0 RPL12 L12 ENSG00000197958 Ribosomal protein L12 9 127447674-127451405 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003403 Approved Renal cancer:7.42e-7 (unfavourable), Head and neck cancer:5.66e-4 (unfavourable) Expressed in all Expressed in all ovary: 3666.1 RPL13 BBC1, D16S444E, L13 ENSG00000167526 Ribosomal protein L13 16 89560657-89566828 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051702 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Endometrial cancer:6.26e-4 (favourable), Renal cancer:6.64e-4 (unfavourable) Expressed in all Expressed in all ovary: 3867.8 RPL13A L13A, TSTA1 ENSG00000142541 Ribosomal protein L13a 19 49487554-49492308 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA038751 Approved Approved Nucleoli
Cytosol Renal cancer:1.44e-5 (unfavourable), Liver cancer:9.97e-4 (unfavourable) Expressed in all Expressed in all ovary: 4608.9 RPL14 CTG-B33, hRL14, L14, RL14 ENSG00000188846 Ribosomal protein L14 3 40457292-40468587 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA004136 Approved Supported Endoplasmic reticulum
Cytosol Expressed in all Expressed in all breast: 311.2 RPL15 EC45, L15, RPL10, RPLY10, RPYL10 ENSG00000174748 Ribosomal protein L15 3 23916545-23923692 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Expressed in all Expressed in all ovary: 3471.4 RPL17 L17, rpL23 ENSG00000265681 Ribosomal protein L17 18 49488453-49492523 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043724, HPA046385 Supported Supported Endoplasmic reticulum
Cytosol Liver cancer:3.60e-5 (unfavourable) Expressed in all Expressed in all ovary: 4386.6 RPL17-C18orf32 ENSG00000215472 RPL17-C18orf32 readthrough 18 49481681-49492479 Predicted intracellular proteins Evidence at protein level HPA043724, HPA046385 Approved Supported Endoplasmic reticulum
Cytosol Not detected Expressed in all cerebral cortex: 66.4 RPL18 L18 ENSG00000063177 Ribosomal protein L18 19 48615328-48619536 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046572 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:1.21e-4 (unfavourable) Expressed in all Expressed in all ovary: 2568.3 RPL18A L18A ENSG00000105640 Ribosomal protein L18a 19 17859876-17864153 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055259 Approved Approved Nucleoli
Cytosol Renal cancer:1.48e-4 (unfavourable) Expressed in all Expressed in all ovary: 3083.8 RPL19 DKFZp779D216, FLJ27452, L19, MGC71997 ENSG00000108298 Ribosomal protein L19 17 39200283-39204727 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043014, HPA051987 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:6.87e-5 (unfavourable) Expressed in all Expressed in all ovary: 4342.3 RPL21 DKFZp686C06101, FLJ27458, L21, MGC104274, MGC104275, MGC71252 ENSG00000122026 Ribosomal protein L21 13 27251309-27256691 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047252 Approved Supported Nucleoli fibrillar center
Endoplasmic reticulum
Cytosol Melanoma:6.66e-4 (unfavourable) Expressed in all Expressed in all ovary: 2378.0 RPL22 EAP, L22 ENSG00000116251 Ribosomal protein L22 1 6181269-6209389 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Expressed in all Expressed in all ovary: 1344.6 RPL22L1 ENSG00000163584 Ribosomal protein L22-like 1 3 170864875-170870483 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA056207 Uncertain Renal cancer:5.13e-12 (unfavourable), Ovarian cancer:8.60e-5 (favourable) Expressed in all Expressed in all appendix: 89.9 RPL23 L23, rpL17 ENSG00000125691 Ribosomal protein L23 17 38847865-38853843 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003373 Approved Supported Cytosol Renal cancer:4.19e-5 (unfavourable) Expressed in all Expressed in all ovary: 4483.4 RPL23A L23A ENSG00000198242 Ribosomal protein L23a 17 28719393-28724359 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051754, HPA077474 Approved Approved Nucleoli fibrillar center
Cytosol Renal cancer:5.16e-6 (unfavourable) Expressed in all Expressed in all ovary: 2748.3 RPL24 L24 ENSG00000114391 Ribosomal protein L24 3 101681091-101686782 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA051653 Approved Validated Endoplasmic reticulum
Cytosol Renal cancer:2.72e-5 (unfavourable), Thyroid cancer:8.25e-4 (favourable) Expressed in all Expressed in all ovary: 2886.8 RPL26 L26 ENSG00000161970 Ribosomal protein L26 17 8377520-8383213 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA030449, CAB037301 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all breast: 5169.8 RPL26L1 RPL26P1 ENSG00000037241 Ribosomal protein L26-like 1 5 172958729-172969771 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA030449 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Head and neck cancer:2.49e-4 (unfavourable) Expressed in all Expressed in all testis: 124.7 RPL27 L27 ENSG00000131469 Ribosomal protein L27 17 42998273-43002959 Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA002649 Approved Renal cancer:7.80e-8 (unfavourable) Expressed in all Expressed in all lymph node: 2459.3 RPL27A L27A ENSG00000166441 Ribosomal protein L27a 11 8682411-8714759 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA060776, HPA063379 Supported Supported Endoplasmic reticulum
Cytosol Renal cancer:2.83e-10 (unfavourable), Breast cancer:7.84e-5 (favourable) Expressed in all Expressed in all lymph node: 2865.3 RPL28 FLJ43307, L28 ENSG00000108107 Ribosomal protein L28 19 55385345-55403250 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050459 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:6.61e-5 (unfavourable) Expressed in all Expressed in all lymph node: 2004.1 RPL29 HIP, HUMRPL29, L29, RPL29P10 ENSG00000162244 Ribosomal protein L29 3 51993600-51995942 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA069064 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 2735.7 RPL3 L3 ENSG00000100316 Ribosomal protein L3 22 39312882-39320389 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA003365 Uncertain Supported Nucleoli
Cytosol Expressed in all Expressed in all ovary: 5662.0 RPL30 L30 ENSG00000156482 Ribosomal protein L30 8 98024851-98046469 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA002651 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:1.41e-9 (unfavourable) Expressed in all Expressed in all ovary: 5893.2 RPL31 L31 ENSG00000071082 Ribosomal protein L31 2 101001715-101024032 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA072263 Approved Renal cancer:8.08e-6 (unfavourable) Expressed in all Expressed in all ovary: 5517.7 RPL32 L32 ENSG00000144713 Ribosomal protein L32 3 12834485-12841588 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047501, HPA051994 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 4499.5 RPL34 L34 ENSG00000109475 Ribosomal protein L34 4 108620566-108630412 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA035139 Uncertain Supported Nucleoli
Endoplasmic reticulum
Cytosol Endometrial cancer:2.76e-5 (favourable) Expressed in all Expressed in all breast: 4590.2 RPL35 L35 ENSG00000136942 Ribosomal protein L35 9 124857880-124861981 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA006047 Approved Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 2745.4 RPL35A L35A ENSG00000182899 Ribosomal protein L35a 3 197949987-197956610 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Renal cancer:1.37e-6 (unfavourable), Pancreatic cancer:4.43e-4 (unfavourable), Liver cancer:9.89e-4 (unfavourable) Expressed in all Expressed in all ovary: 2038.5 RPL36 DKFZp566B023, L36 ENSG00000130255 Ribosomal protein L36 19 5674947-5691876 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047153 Supported Uncertain Endoplasmic reticulum
Cytosol Renal cancer:2.32e-4 (unfavourable) Expressed in all Expressed in all ovary: 2366.8 RPL36A L36A, RPL44 ENSG00000241343 Ribosomal protein L36a X 101390824-101396154 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA063979, HPA077586 Uncertain Supported Plasma membrane
Cytosol Renal cancer:8.81e-11 (unfavourable) Expressed in all Expressed in all ovary: 3443.9 RPL36AL RPL36A ENSG00000165502 Ribosomal protein L36a-like 14 49618519-49620685 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA077586 Approved Plasma membrane
Cytosol Thyroid cancer:2.83e-4 (favourable) Expressed in all Expressed in all ovary: 528.8 RPL37 L37 ENSG00000145592 Ribosomal protein L37 5 40825262-40835335 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Renal cancer:2.67e-6 (unfavourable), Urothelial cancer:6.34e-4 (favourable) Expressed in all Expressed in all breast: 920.6 RPL37A L37A ENSG00000197756 Ribosomal protein L37a 2 216498189-216579180 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA065327 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:1.14e-4 (unfavourable) Expressed in all Expressed in all ovary: 4507.8 RPL38 L38 ENSG00000172809 Ribosomal protein L38 17 74203582-74210655 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA052543 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:6.17e-8 (unfavourable), Head and neck cancer:2.51e-4 (unfavourable) Expressed in all Expressed in all ovary: 2575.5 RPL39 L39, RPL39P42 ENSG00000198918 Ribosomal protein L39 X 119786504-119791643 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047105 Uncertain Renal cancer:1.71e-9 (unfavourable) Expressed in all Expressed in all breast: 5335.3 RPL4 L4 ENSG00000174444 Ribosomal protein L4 15 66498015-66524532 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA034600 Uncertain Supported Nucleoli
Nuclear bodies
Endoplasmic reticulum
Cytosol Renal cancer:5.20e-5 (unfavourable) Expressed in all Expressed in all ovary: 3679.0 RPL41 L41 ENSG00000229117 Ribosomal protein L41 12 56116586-56117943 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA053169 Approved Expressed in all Expressed in all ovary: 10553.2 RPL5 L5, PPP1R135 ENSG00000122406 Ribosomal protein L5 1 92832025-92841924 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043717 Approved Renal cancer:6.81e-5 (unfavourable) Expressed in all Expressed in all ovary: 4031.6 RPL6 L6, TAXREB107, TXREB1 ENSG00000089009 Ribosomal protein L6 12 112405190-112418838 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA068418 Approved Renal cancer:6.95e-4 (unfavourable) Expressed in all Expressed in all ovary: 3211.7 RPL7 humL7-1, L7 ENSG00000147604 Ribosomal protein L7 8 73290267-73295789 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA058373 Approved Approved Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 5517.3 RPL7A L7A, SURF3, TRUP ENSG00000148303 Ribosomal protein L7a 9 133348214-133351426 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Ovarian cancer:3.60e-5 (unfavourable), Liver cancer:8.99e-4 (unfavourable) Expressed in all Expressed in all ovary: 2609.1 RPL7L1 dJ475N16.4 ENSG00000146223 Ribosomal protein L7-like 1 6 42879618-42889925 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA046049, HPA050478 Approved Nucleoli
Mitochondria Liver cancer:8.53e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 70.2 RPL8 L8 ENSG00000161016 Ribosomal protein L8 8 144789765-144792587 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA045095, HPA050165 Supported Validated Nucleoli
Endoplasmic reticulum
Cytosol Liver cancer:7.22e-4 (unfavourable) Expressed in all Expressed in all ovary: 954.9 RPL9 L9 ENSG00000163682 Ribosomal protein L9 4 39454124-39458948 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003372 Approved Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:7.34e-4 (unfavourable) Expressed in all Expressed in all epididymis: 2666.1 RPLP0 L10E, LP0, P0, PRLP0, RPP0 ENSG00000089157 Ribosomal protein, large, P0 12 120196686-120201235 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003512 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:7.66e-12 (unfavourable) Expressed in all Expressed in all breast: 2849.3 RPLP1 LP1 ENSG00000137818 Ribosomal protein, large, P1 15 69452784-69456194 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003368 Uncertain Validated Endoplasmic reticulum
Cytosol Renal cancer:2.30e-9 (unfavourable) Expressed in all Expressed in all ovary: 1839.8 RPLP2 D11S2243E, LP2, MGC71408, P2, RPP2 ENSG00000177600 Ribosomal protein, large, P2 11 809647-812880 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA053635 Approved Renal cancer:2.19e-6 (unfavourable), Liver cancer:9.14e-4 (unfavourable) Expressed in all Expressed in all ovary: 1165.2 RPN1 OST1 ENSG00000163902 Ribophorin I 3 128619970-128681075 Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB009748, HPA026828, HPA051520 Supported Validated Endoplasmic reticulum Liver cancer:4.80e-4 (unfavourable) Expressed in all Expressed in all epididymis: 416.3 RPN2 RIBIIR, RPN-II, RPNII, SWP1 ENSG00000118705 Ribophorin II 20 37178410-37241623 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008297, CAB019277, HPA025922 Supported Supported Endoplasmic reticulum Renal cancer:1.44e-10 (unfavourable), Liver cancer:1.38e-4 (unfavourable), Urothelial cancer:2.44e-4 (unfavourable) Expressed in all Expressed in all epididymis: 358.1 RPP14 P14 ENSG00000163684 Ribonuclease P/MRP 14kDa subunit 3 58306247-58324695 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036194 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.07e-10 (favourable), Thyroid cancer:2.96e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 21.1 RPP25L bA296L22.5, C9orf23, MGC29635 ENSG00000164967 Ribonuclease P/MRP 25kDa subunit-like 9 34610486-34612104 Predicted intracellular proteins Evidence at protein level HPA052187, HPA059698 Uncertain Supported Nucleus Renal cancer:3.01e-9 (favourable), Urothelial cancer:8.21e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 38.7 RPP30 TSG15 ENSG00000148688 Ribonuclease P/MRP 30kDa subunit 10 90871716-90908553 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037578 Approved Approved Nucleus
Nucleoli
Microtubule ends
Cytosol Renal cancer:1.01e-6 (unfavourable) Expressed in all Expressed in all testis: 50.4 RPP38 ENSG00000152464 Ribonuclease P/MRP 38kDa subunit 10 15097180-15139818 Enzymes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA045128 Supported Nucleoli Urothelial cancer:2.89e-6 (favourable), Liver cancer:1.46e-4 (unfavourable), Renal cancer:6.25e-4 (unfavourable) Expressed in all Expressed in all testis: 76.5 RPRD1A FLJ10656, HsT3101, P15RS ENSG00000141425 Regulation of nuclear pre-mRNA domain containing 1A 18 35984387-36067576 Predicted intracellular proteins Evidence at protein level HPA040602 Supported Supported Nucleus
Golgi apparatus Expressed in all Expressed in all epididymis: 138.0 RPRD1B C20orf77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, NET60 ENSG00000101413 Regulation of nuclear pre-mRNA domain containing 1B 20 38033546-38127780 Predicted intracellular proteins Evidence at protein level HPA066290 Supported Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all parathyroid gland: 29.0 RPRD2 FLJ32145, HSPC099, KIAA0460 ENSG00000163125 Regulation of nuclear pre-mRNA domain containing 2 1 150363091-150476566 Predicted intracellular proteins Evidence at protein level HPA061693 Approved Nucleoplasm
Vesicles Expressed in all Expressed in all thyroid gland: 38.2 RPS10 MGC88819, S10 ENSG00000124614 Ribosomal protein S10 6 34417454-34426125 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047268, HPA048084 Approved Supported Cytosol Renal cancer:2.57e-6 (unfavourable) Expressed in all Expressed in all ovary: 2696.6 RPS11 S11 ENSG00000142534 Ribosomal protein S11 19 49496365-49499689 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA049719 Uncertain Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:3.50e-7 (unfavourable) Expressed in all Expressed in all ovary: 6646.8 RPS12 S12 ENSG00000112306 Ribosomal protein S12 6 132814441-132817564 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA006124, HPA006365 Approved Supported Cytosol Renal cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all ovary: 3951.0 RPS13 S13 ENSG00000110700 Ribosomal protein S13 11 17074389-17077787 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA005985 Uncertain Approved Nuclear bodies Renal cancer:1.54e-4 (unfavourable) Expressed in all Expressed in all ovary: 2360.7 RPS14 EMTB, S14 ENSG00000164587 Ribosomal protein S14 5 150443190-150449756 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA018504 Uncertain Validated Endoplasmic reticulum
Cytosol Liver cancer:7.73e-4 (unfavourable), Renal cancer:8.69e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 1979.7 RPS15 MGC111130, RIG, S15 ENSG00000115268 Ribosomal protein S15 19 1438358-1440494 Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA054510, HPA057793 Supported Approved Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 1335.1 RPS15A S15A ENSG00000134419 Ribosomal protein S15a 16 18781295-18790383 Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins Evidence at protein level HPA047103 Supported Renal cancer:7.29e-7 (unfavourable) Expressed in all Expressed in all breast: 4769.2 RPS16 S16 ENSG00000105193 Ribosomal protein S16 19 39433207-39435948 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA064222 Approved Validated Endoplasmic reticulum
Cytosol Expressed in all Expressed in all ovary: 3699.3 RPS17 MGC72007, RPS17L, RPS17L1, RPS17L2, S17 ENSG00000182774 Ribosomal protein S17 15 82536753-82540564 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055060 Approved Supported Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:1.78e-4 (unfavourable) Expressed in all Expressed in all ovary: 1569.8 RPS18 D6S218E, HKE3, KE-3, KE3, S18 ENSG00000231500 Ribosomal protein S18 6 33272010-33276510 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA050159, HPA055007 Approved Supported Cytosol Renal cancer:1.15e-10 (unfavourable), Breast cancer:9.81e-4 (favourable) Expressed in all Expressed in all ovary: 1301.5 RPS19 DBA, S19 ENSG00000105372 Ribosomal protein S19 19 41859918-41872926 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level Renal cancer:2.32e-8 (unfavourable) Expressed in all Expressed in all ovary: 3245.6 RPS19BP1 FLJ21770, MGC52010 ENSG00000187051 Ribosomal protein S19 binding protein 1 22 39529093-39532855 Predicted intracellular proteins Evidence at protein level HPA042874 Uncertain Supported Nucleus
Nucleoli
Cytosol Liver cancer:3.71e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 57.5 RPS2 LLREP3, S2 ENSG00000140988 Ribosomal protein S2 16 1962052-1964860 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055133 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:3.04e-7 (unfavourable), Liver cancer:7.70e-4 (unfavourable) Expressed in all Expressed in all ovary: 3061.1 RPS20 S20 ENSG00000008988 Ribosomal protein S20 8 56067295-56074581 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003570 Approved Supported Endoplasmic reticulum
Cytosol Renal cancer:1.21e-8 (unfavourable) Expressed in all Expressed in all ovary: 4357.5 RPS21 S21 ENSG00000171858 Ribosomal protein S21 20 62387116-62388520 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003371 Approved Validated Endoplasmic reticulum
Cytosol Liver cancer:8.46e-4 (unfavourable) Expressed in all Expressed in all ovary: 2347.4 RPS23 S23 ENSG00000186468 Ribosomal protein S23 5 82273358-82278577 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA054853 Approved Validated Endoplasmic reticulum
Cytosol Renal cancer:2.17e-4 (unfavourable), Liver cancer:4.72e-4 (unfavourable) Expressed in all Expressed in all ovary: 4311.4 RPS24 S24 ENSG00000138326 Ribosomal protein S24 10 78033760-78056812 Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA003364 Approved Approved Nuclear bodies
Endoplasmic reticulum
Cytosol Renal cancer:1.10e-10 (unfavourable), Breast cancer:1.50e-4 (favourable) Expressed in all Expressed in all ovary: 6812.2 RPS25 S25 ENSG00000118181 Ribosomal protein S25 11 119015712-119018691 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA031801 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:3.00e-7 (unfavourable) Expressed in all Expressed in all ovary: 944.6 RPS26 S26 ENSG00000197728 Ribosomal protein S26 12 56041853-56044675 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043961, HPA055803 Uncertain Validated Nucleoli
Endoplasmic reticulum
Cytosol Expressed in all Expressed in all thyroid gland: 822.8 RPS27 MPS-1, MPS1, S27 ENSG00000177954 Ribosomal protein S27 1 153990759-153992150 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA066851 Approved Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:4.86e-7 (unfavourable), Breast cancer:9.69e-4 (favourable) Expressed in all Expressed in all ovary: 11931.0 RPS27A S27A, Uba80, UBCEP80 ENSG00000143947 Ribosomal protein S27a 2 55231903-55235853 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB033319, HPA041344, HPA049132, HPA054087 Supported Approved Nucleoli
Endoplasmic reticulum
Cytosol Renal cancer:2.60e-6 (unfavourable), Liver cancer:2.26e-4 (unfavourable) Expressed in all Expressed in all ovary: 3409.3 RPS27L ENSG00000185088 Ribosomal protein S27-like 15 63125872-63158021 Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins Evidence at protein level HPA066851 Supported Nucleoli
Endoplasmic reticulum
Cytosol Endometrial cancer:9.08e-6 (favourable) Expressed in all Expressed in all adrenal gland: 223.3 RPS28 S28 ENSG00000233927 Ribosomal protein S28 19 8321158-8323340 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047132 Approved Approved Cytosol Endometrial cancer:2.47e-4 (favourable) Expressed in all Expressed in all ovary: 306.8 RPS29 S29 ENSG00000213741 Ribosomal protein S29 14 49570984-49599164 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA004107 Approved Supported Endoplasmic reticulum
Cytosol Breast cancer:2.66e-4 (favourable) Expressed in all Expressed in all breast: 3614.6 RPS3 FLJ26283, FLJ27450, MGC87870, S3 ENSG00000149273 Ribosomal protein S3 11 75399486-75422280 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA063339 Uncertain Supported Endoplasmic reticulum
Cytosol Renal cancer:6.92e-6 (unfavourable) Expressed in all Expressed in all ovary: 3526.1 RPS3A MFTL, S3A ENSG00000145425 Ribosomal protein S3A 4 151099573-151104652 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA047100, HPA053454 Approved Validated Nucleoli
Endoplasmic reticulum
Cytosol Liver cancer:6.56e-4 (unfavourable) Expressed in all Expressed in all ovary: 5244.0 RPS4X CCG2, DXS306, FLJ40595, RPS4, S4, SCAR, SCR10 ENSG00000198034 Ribosomal protein S4, X-linked X 72255679-72277300 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA000857 Supported Renal cancer:4.50e-6 (unfavourable), Thyroid cancer:4.22e-4 (favourable) Expressed in all Expressed in all ovary: 1941.1 RPS5 S5 ENSG00000083845 Ribosomal protein S5 19 58386400-58394806 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA055878, HPA061979 Supported Supported Endoplasmic reticulum
Cytosol Liver cancer:1.12e-5 (unfavourable), Renal cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all ovary: 2644.2 RPS6 S6 ENSG00000137154 Ribosomal protein S6 9 19375715-19380254 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB004027, HPA031153 Supported Validated Endoplasmic reticulum
Cytosol Endometrial cancer:4.12e-4 (favourable) Expressed in all Expressed in all ovary: 4794.1 RPS6KA2 HU-2, RSK, RSK3 ENSG00000071242 Ribosomal protein S6 kinase, 90kDa, polypeptide 2 6 166409364-166906451 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB026243, HPA045061, HPA054237, CAB069428 Approved Supported Nucleoplasm Renal cancer:2.86e-5 (favourable), Ovarian cancer:8.63e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.0 RPS6KA3 CLS, HU-3, MRX19, RSK, RSK2 ENSG00000177189 Ribosomal protein S6 kinase, 90kDa, polypeptide 3 X 20149911-20267100 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003221, CAB003853, CAB013520 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 91.0 RPS6KA4 MSK2, RSK-B ENSG00000162302 Ribosomal protein S6 kinase, 90kDa, polypeptide 4 11 64359148-64372215 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008649, HPA023225 Approved Supported Nucleus
Cytosol Liver cancer:8.17e-4 (unfavourable), Lung cancer:9.27e-4 (unfavourable) Expressed in all Expressed in all spleen: 23.6 RPS6KB1 p70(S6K)-alpha, PS6K, S6K1, STK14A ENSG00000108443 Ribosomal protein S6 kinase, 70kDa, polypeptide 1 17 59893046-59950564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003838, CAB018346, HPA039442 Approved Supported Nucleoplasm Renal cancer:5.09e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.0 RPS6KB2 KLS, P70-BETA, p70S6Kb, STK14B ENSG00000175634 Ribosomal protein S6 kinase, 70kDa, polypeptide 2 11 67428460-67435408 Enzymes, Predicted intracellular proteins Evidence at protein level HPA010010, CAB019404 Approved Supported Cytosol Renal cancer:2.03e-7 (unfavourable) Expressed in all Expressed in all skin: 65.4 RPS6KC1 humS6PKh1 ENSG00000136643 Ribosomal protein S6 kinase, 52kDa, polypeptide 1 1 213051233-213274773 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026531, HPA031565 Approved Validated Endosomes
Lysosomes
Cytosol Renal cancer:2.70e-4 (unfavourable) Expressed in all Expressed in all testis: 35.2 RPS7 S7 ENSG00000171863 Ribosomal protein S7 2 3575205-3580919 Disease related genes, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA056586 Approved Approved Endoplasmic reticulum
Cytosol Renal cancer:1.34e-8 (unfavourable), Liver cancer:5.27e-4 (unfavourable) Expressed in all Expressed in all ovary: 2607.1 RPS8 S8 ENSG00000142937 Ribosomal protein S8 1 44775251-44778779 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029266 Supported Endoplasmic reticulum
Cytosol Renal cancer:9.05e-9 (unfavourable), Liver cancer:2.36e-5 (unfavourable) Expressed in all Expressed in all ovary: 5531.8 RPS9 S9 ENSG00000170889 Ribosomal protein S9 19 54200742-54249003 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA048746 Approved Renal cancer:1.63e-4 (unfavourable), Breast cancer:9.23e-4 (favourable) Expressed in all Expressed in all ovary: 112.5 RPSA 37LRP, LAMR1, LRP, p40, SA ENSG00000168028 Ribosomal protein SA 3 39406689-39412542 Plasma proteins, Predicted intracellular proteins, Ribosomal proteins Evidence at protein level CAB009561 Approved Supported Plasma membrane
Cytosol Expressed in all Expressed in all ovary: 2079.5 RPUSD1 C16orf40, MGC19600, RLUCL ENSG00000007376 RNA pseudouridylate synthase domain containing 1 16 784974-788397 Predicted intracellular proteins Evidence at protein level HPA041144, HPA041938 Approved Approved Nucleus
Golgi apparatus
Cell Junctions
Cytosol Expressed in all Expressed in all appendix: 13.4 RPUSD3 MGC29784 ENSG00000156990 RNA pseudouridylate synthase domain containing 3 3 9837849-9844602 Predicted intracellular proteins Evidence at protein level HPA037551, HPA037552 Uncertain Approved Nucleus Liver cancer:1.73e-5 (unfavourable) Expressed in all Expressed in all testis: 54.2 RPUSD4 FLJ14494 ENSG00000165526 RNA pseudouridylate synthase domain containing 4 11 126202094-126211692 Predicted intracellular proteins Evidence at protein level HPA039689 Approved Approved Nucleoplasm
Mitochondria Liver cancer:1.24e-4 (unfavourable), Colorectal cancer:6.14e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 44.9 RQCD1 CAF40, CNOT9, CT129, RCD1, RCD1+ ENSG00000144580 RCD1 required for cell differentiation1 homolog (S. pombe) 2 218568580-218597080 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046622 Approved Renal cancer:4.69e-9 (unfavourable), Liver cancer:8.41e-9 (unfavourable) Expressed in all Expressed in all testis: 48.8 RRAGA FIP-1, RAGA ENSG00000155876 Ras-related GTP binding A 9 19049395-19050983 Predicted intracellular proteins Evidence at protein level HPA003734 Supported Approved Golgi apparatus
Vesicles Head and neck cancer:7.43e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 128.4 RRAGB ENSG00000083750 Ras-related GTP binding B X 55717739-55758774 Predicted intracellular proteins Evidence at protein level HPA003734 Approved Approved Golgi apparatus
Vesicles Lung cancer:3.64e-6 (favourable), Glioma:5.36e-5 (favourable), Colorectal cancer:7.60e-4 (unfavourable) Expressed in all Expressed in all epididymis: 41.5 RRAGC FLJ13311, GTR2 ENSG00000116954 Ras-related GTP binding C 1 38838198-38859823 Predicted intracellular proteins Evidence at protein level HPA018247, HPA055489 Supported Supported Nucleus
Vesicles Liver cancer:9.97e-9 (unfavourable) Expressed in all Expressed in all adipose tissue: 40.3 RRAGD bA11D8.2.1, DKFZP761H171 ENSG00000025039 Ras-related GTP binding D 6 89364636-89412270 Predicted intracellular proteins Evidence at protein level HPA068664 Approved Approved Nucleoplasm
Centrosome Renal cancer:8.47e-8 (favourable), Liver cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 46.7 RRAS ENSG00000126458 Related RAS viral (r-ras) oncogene homolog 19 49635292-49640201 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010160, HPA060364, CAB069439 Uncertain Approved Vesicles Renal cancer:1.54e-9 (unfavourable), Glioma:6.03e-5 (unfavourable), Lung cancer:5.28e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 206.9 RRAS2 TC21 ENSG00000133818 Related RAS viral (r-ras) oncogene homolog 2 11 14277926-14364506 Disease related genes, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB010420, HPA050942 Approved Approved Nucleus
Cytosol Pancreatic cancer:2.44e-4 (unfavourable), Liver cancer:3.31e-4 (unfavourable), Head and neck cancer:7.80e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 63.8 RRBP1 ES/130, hES ENSG00000125844 Ribosome binding protein 1 20 17613678-17682295 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009026, HPA011924 Supported Validated Endoplasmic reticulum Endometrial cancer:1.41e-4 (favourable), Urothelial cancer:9.38e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 219.5 RREB1 HNT ENSG00000124782 Ras responsive element binding protein 1 6 7107597-7251980 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001756, HPA034843 Approved Supported Nucleoli fibrillar center
Nuclear speckles Renal cancer:1.41e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 22.9 RRM1 ENSG00000167325 Ribonucleotide reductase M1 11 4094707-4138876 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022093, HPA057265, HPA064297 Supported Validated Cytosol Liver cancer:1.53e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.5 RRM2B p53R2 ENSG00000048392 Ribonucleotide reductase M2 B (TP53 inducible) 8 102204502-102239118 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB006854, HPA028812 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 73.7 RRN3 DKFZp566E104, TIF-IA ENSG00000085721 RRN3 homolog, RNA polymerase I transcription factor 16 15060022-15094317 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049837 Supported Validated Nucleoli Expressed in all Expressed in all parathyroid gland: 21.9 RRNAD1 C1orf66, CGI-41 ENSG00000143303 Ribosomal RNA adenine dimethylase domain containing 1 1 156728442-156736960 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA047426 Approved Approved Nucleoli
Cytosol Colorectal cancer:5.60e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.0 RRP1 D21S2056E, NNP-1, Nop52, RRP1A ENSG00000160214 Ribosomal RNA processing 1 21 43789513-43805293 Predicted intracellular proteins Evidence at protein level HPA016818, HPA018166 Approved Validated Nucleoli Renal cancer:6.29e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 12.1 RRP12 KIAA0690 ENSG00000052749 Ribosomal RNA processing 12 homolog 10 97356358-97426076 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA049945 Supported Nucleoli Liver cancer:3.12e-8 (unfavourable), Renal cancer:2.54e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 58.3 RRP1B KIAA0179, Nnp1, PPP1R136, RRP1 ENSG00000160208 Ribosomal RNA processing 1B 21 43659548-43696079 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA017893, HPA020324 Supported Validated Nucleoli Renal cancer:2.95e-9 (unfavourable) Expressed in all Expressed in all testis: 21.7 RRP36 C6orf153, dJ20C7.4 ENSG00000124541 Ribosomal RNA processing 36 6 43021645-43034156 Predicted intracellular proteins Evidence at protein level HPA029904, HPA029905 Uncertain Supported Nucleus
Nucleoli Renal cancer:2.48e-5 (unfavourable), Liver cancer:5.95e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 60.2 RRP7A CGI-96 ENSG00000189306 Ribosomal RNA processing 7 homolog A 22 42509968-42519802 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001586, HPA046768 Approved Approved Nucleus
Nucleoli
Cell Junctions Liver cancer:1.21e-5 (unfavourable) Expressed in all Expressed in all epididymis: 49.0 RRP8 KIAA0409 ENSG00000132275 Ribosomal RNA processing 8, methyltransferase, homolog (yeast) 11 6595075-6603620 Predicted intracellular proteins Evidence at protein level HPA038487, HPA057562 Supported Supported Nucleus
Nucleoli
Cytosol Liver cancer:3.10e-7 (unfavourable) Expressed in all Expressed in all prostate,seminal vesicle: 12.2 RRP9 RNU3IP2, U3-55K ENSG00000114767 Ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 3 51933430-51941941 Predicted intracellular proteins Evidence at protein level HPA038798 Uncertain Supported Nucleus Liver cancer:2.90e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 18.7 RRS1 KIAA0112 ENSG00000179041 Ribosome biogenesis regulator homolog 8 66429028-66430733 Predicted intracellular proteins Evidence at protein level HPA055549, HPA060937 Approved Validated Nucleoli Expressed in all Expressed in all appendix: 16.8 RSAD1 FLJ11164 ENSG00000136444 Radical S-adenosyl methionine domain containing 1 17 50478800-50485975 Predicted intracellular proteins Evidence at protein level HPA022436, HPA022967 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Pancreatic cancer:5.04e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 36.0 RSBN1 FLJ11220, ROSBIN ENSG00000081019 Round spermatid basic protein 1 1 113761832-113812476 Predicted intracellular proteins Evidence at protein level HPA042124, HPA049484 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Expressed in all Expressed in all bone marrow: 21.9 RSBN1L FLJ42526, FLJ45813, MGC71764 ENSG00000187257 Round spermatid basic protein 1-like 7 77696443-77783022 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA020406, HPA020413 Approved Supported Nuclear speckles
Plasma membrane Lung cancer:3.74e-4 (favourable) Expressed in all Expressed in all testis: 47.0 RSF1 HBXAP, p325, RSF-1, XAP8 ENSG00000048649 Remodeling and spacing factor 1 11 77659996-77821017 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022626, HPA046129, HPA057547, HPA064567 Supported Validated Nucleoplasm Pancreatic cancer:1.61e-4 (unfavourable), Renal cancer:5.94e-4 (favourable) Expressed in all Expressed in all testis: 44.2 RSL1D1 CSIG, DKFZP564M182, L12, PBK1, UTP30 ENSG00000171490 Ribosomal L1 domain containing 1 16 11833850-11851585 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA043483 Supported Validated Nucleoli Liver cancer:1.38e-4 (unfavourable), Head and neck cancer:2.95e-4 (unfavourable), Renal cancer:3.24e-4 (unfavourable) Expressed in all Expressed in all ovary: 145.4 RSL24D1 C15orf15, HRP-L30-iso, L30, RPL24, RPL24L ENSG00000137876 Ribosomal L24 domain containing 1 15 55180806-55197067 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA062724, HPA063392 Supported Validated Nucleus
Nucleoli Expressed in all Expressed in all ovary: 124.1 RSPRY1 KIAA1972 ENSG00000159579 Ring finger and SPRY domain containing 1 16 57186137-57240475 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003729 Approved Head and neck cancer:8.21e-5 (unfavourable) Expressed in all Expressed in all testis: 39.4 RSRC1 BM-011, MGC12197, SFRS21, SRrp53 ENSG00000174891 Arginine/serine-rich coiled-coil 1 3 158105855-158545730 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044792 Supported Approved Nuclear speckles Endometrial cancer:7.40e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.1 RSRC2 FLJ11021 ENSG00000111011 Arginine/serine-rich coiled-coil 2 12 122503458-122527000 Predicted intracellular proteins Evidence at protein level HPA040070, HPA048183 Uncertain Validated Nucleoli fibrillar center
Nuclear speckles
Cytosol Liver cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 42.6 RSRP1 C1orf63, DJ465N24.2.1 ENSG00000117616 Arginine/serine-rich protein 1 1 25242237-25338213 Predicted intracellular proteins Evidence at protein level HPA058992, HPA067651 Uncertain Approved Nucleoplasm Urothelial cancer:2.91e-5 (favourable) Expressed in all Expressed in all adrenal gland: 34.5 RSU1 FLJ31034, RSP-1 ENSG00000148484 Ras suppressor protein 1 10 16590611-16817528 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA025927 Uncertain Approved Vesicles Renal cancer:9.32e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 58.1 RTCA RPC, RTC1, RTCD1 ENSG00000137996 RNA 3'-terminal phosphate cyclase 1 100266207-100292769 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027982, HPA027990, HPA028151 Uncertain Validated Nucleus Liver cancer:2.76e-5 (unfavourable) Expressed in all Expressed in all duodenum: 36.0 RTCB C22orf28, FAAP, HSPC117 ENSG00000100220 RNA 2',3'-cyclic phosphate and 5'-OH ligase 22 32387582-32412255 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000535, HPA001103 Supported Supported Nucleoplasm
Vesicles
Cytosol Renal cancer:4.25e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 102.3 RTEL1 bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL ENSG00000258366 Regulator of telomere elongation helicase 1 20 63657810-63696253 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA067329 Supported Nuclear bodies Not detected Expressed in all testis: 13.2 RTF1 KIAA0252 ENSG00000137815 RTF1 homolog, Paf1/RNA polymerase II complex component 15 41408408-41483563 Predicted intracellular proteins Evidence at protein level HPA006714 Approved Approved Nucleus
Cytosol Pancreatic cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 62.7 RTFDC1 C20orf43, CDAO5, HSPC164 ENSG00000022277 Replication termination factor 2 domain containing 1 20 56468585-56519449 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053986 Approved Approved Nucleus
Nucleoli Liver cancer:1.31e-4 (unfavourable), Endometrial cancer:6.35e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 140.7 RTN3 ASYIP, HAP, NSPL2, NSPLII, RTN3-A1 ENSG00000133318 Reticulon 3 11 63681446-63759891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015649, HPA015650 Supported Supported Endoplasmic reticulum Liver cancer:1.30e-6 (unfavourable), Renal cancer:9.87e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 1033.6 RTN4 ASY, KIAA0886, NOGO, NSP-CL ENSG00000115310 Reticulon 4 2 54972187-55112621 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB005388, HPA023977 Supported Validated Endoplasmic reticulum Head and neck cancer:1.00e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 638.6 RUBCN KIAA0226, rubicon, rundataxin ENSG00000145016 RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein 3 197671393-197749727 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050908, HPA054497 Approved Supported Vesicles
Cytosol Liver cancer:9.91e-5 (unfavourable), Prostate cancer:1.62e-4 (unfavourable), Colorectal cancer:6.65e-4 (unfavourable) Expressed in all Expressed in all spleen: 24.7 RUFY1 FLJ22251, RABIP4, ZFYVE12 ENSG00000176783 RUN and FYVE domain containing 1 5 179550558-179610026 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038804, HPA057614 Approved Supported Nucleus
Vesicles
Cytosol Expressed in all Expressed in all spleen: 41.4 RUFY2 FLJ10063, KIAA1537, RABIP4R, ZFYVE13 ENSG00000204130 RUN and FYVE domain containing 2 10 68341107-68407294 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039792 Approved Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 36.9 RUFY3 KIAA0871, RIPx, Singar1, ZFYVE30 ENSG00000018189 RUN and FYVE domain containing 3 4 70704204-70807315 Predicted intracellular proteins Evidence at protein level HPA022952, HPA022970 Approved Supported Cytosol Pancreatic cancer:8.02e-5 (favourable), Head and neck cancer:1.28e-4 (favourable), Liver cancer:8.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 143.4 RUNDC1 DKFZp761H0421 ENSG00000198863 RUN domain containing 1 17 42980565-42993690 Predicted intracellular proteins Evidence at protein level HPA023726 Uncertain Approved Nuclear speckles
Cytosol Endometrial cancer:6.93e-5 (favourable) Expressed in all Expressed in all fallopian tube: 23.3 RUSC1 NESCA ENSG00000160753 RUN and SH3 domain containing 1 1 155320896-155331114 Predicted intracellular proteins Evidence at protein level HPA028510, HPA029922, HPA029923 Approved Supported Cytosol Liver cancer:7.78e-6 (unfavourable), Renal cancer:9.24e-6 (unfavourable), Prostate cancer:2.65e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 38.6 RUSC2 KIAA0375 ENSG00000198853 RUN and SH3 domain containing 2 9 35490127-35561898 Predicted intracellular proteins Evidence at protein level HPA021297 Uncertain Expressed in all Expressed in all cerebral cortex: 48.7 RUVBL1 ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a ENSG00000175792 RuvB-like AAA ATPase 1 3 128064778-128153914 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019947, HPA019948 Supported Supported Nucleoplasm
Cytosol Liver cancer:1.21e-8 (unfavourable) Expressed in all Expressed in all fallopian tube: 80.9 RUVBL2 ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b ENSG00000183207 RuvB-like AAA ATPase 2 19 48993448-49015995 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012432, HPA042880, HPA067966 Supported Supported Nucleoplasm
Centrosome
Cytosol Liver cancer:9.28e-4 (unfavourable) Expressed in all Expressed in all testis: 71.6 RWDD1 PTD013 ENSG00000111832 RWD domain containing 1 6 116571367-116597675 Predicted intracellular proteins Evidence at protein level HPA028712, HPA028713 Approved Liver cancer:5.16e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 62.0 RWDD4 FAM28A, MGC10198, RWDD4A ENSG00000182552 RWD domain containing 4 4 183639635-183659225 Predicted intracellular proteins Evidence at protein level HPA036501, HPA036502 Approved Approved Intermediate filaments Renal cancer:1.01e-6 (favourable) Expressed in all Expressed in all adrenal gland: 68.5 RYK D3S3195, JTK5, JTK5A, RYK1 ENSG00000163785 Receptor-like tyrosine kinase 3 134065303-134250744 Predicted membrane proteins Evidence at protein level CAB034117, HPA045503 Uncertain Approved Nucleus
Nucleoli fibrillar center Liver cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all ovary: 100.7 S100A10 42C, ANX2LG, CAL1L, CLP11, P11 ENSG00000197747 S100 calcium binding protein A10 1 151982915-151994390 Predicted membrane proteins Evidence at protein level HPA003340, CAB025484 Supported Approved Mitochondria Renal cancer:3.80e-8 (unfavourable), Lung cancer:2.66e-5 (unfavourable), Liver cancer:1.00e-4 (unfavourable), Head and neck cancer:3.33e-4 (unfavourable), Urothelial cancer:3.84e-4 (unfavourable), Pancreatic cancer:3.88e-4 (unfavourable) Expressed in all Expressed in all esophagus: 978.3 S100A11 S100C ENSG00000163191 S100 calcium binding protein A11 1 152032506-152047907 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034320, HPA042745 Supported Renal cancer:3.24e-6 (unfavourable), Liver cancer:3.64e-5 (unfavourable) Expressed in all Expressed in all esophagus: 2733.4 S100A13 ENSG00000189171 S100 calcium binding protein A13 1 153618787-153631360 Predicted intracellular proteins Evidence at protein level HPA019592, CAB025494 Approved Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Renal cancer:1.97e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 330.1 S100A4 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98 ENSG00000196154 S100 calcium binding protein A4 1 153543613-153550136 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002618, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228 Supported Validated Plasma membrane Head and neck cancer:4.03e-5 (favourable), Renal cancer:2.90e-4 (unfavourable) Expressed in all Expressed in all lung: 990.8 S100A6 2A9, CABP, CACY, PRA ENSG00000197956 S100 calcium binding protein A6 1 153534599-153536244 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002601, HPA007575, CAB040549 Supported Validated Cytosol Urothelial cancer:7.56e-4 (favourable) Expressed in all Expressed in all lung: 1681.2 S100PBP FLJ12903, S100PBPR ENSG00000116497 S100P binding protein 1 32816767-32858879 Predicted intracellular proteins Evidence at protein level HPA027242, HPA027328 Approved Supported Nuclear speckles Liver cancer:1.26e-6 (unfavourable), Head and neck cancer:5.22e-5 (favourable), Renal cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all testis: 62.7 S1PR1 CD363, D1S3362, edg-1, EDG1 ENSG00000170989 Sphingosine-1-phosphate receptor 1 1 101236888-101241518 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level CAB010104, HPA075568 Supported Supported Vesicles Urothelial cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 86.5 SAAL1 FLJ41463 ENSG00000166788 Serum amyloid A-like 1 11 18069935-18106091 Predicted intracellular proteins Evidence at protein level HPA039003, HPA039004 Approved Supported Nucleoplasm Renal cancer:5.78e-5 (unfavourable) Expressed in all Expressed in all testis: 23.1 SACM1L KIAA0851, SAC1 ENSG00000211456 SAC1 suppressor of actin mutations 1-like (yeast) 3 45689056-45745424 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039573, HPA069869 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:5.47e-7 (favourable) Expressed in all Expressed in all thyroid gland: 67.2 SAE1 AOS1, FLJ3091, Sua1 ENSG00000142230 SUMO1 activating enzyme subunit 1 19 47113274-47210636 Predicted intracellular proteins Evidence at protein level HPA041906, HPA043552 Supported Liver cancer:5.49e-8 (unfavourable), Renal cancer:8.15e-5 (unfavourable), Thyroid cancer:2.76e-4 (unfavourable) Expressed in all Expressed in all testis: 145.1 SAFB HET, SAFB1 ENSG00000160633 Scaffold attachment factor B 19 5623035-5668478 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001969, HPA016832, HPA020076 Supported Validated Nucleoplasm Pancreatic cancer:9.75e-5 (favourable), Urothelial cancer:1.70e-4 (favourable) Expressed in all Expressed in all spleen: 54.9 SAFB2 KIAA0138 ENSG00000130254 Scaffold attachment factor B2 19 5586999-5624046 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050894 Approved Supported Nucleoplasm
Nuclear bodies
Vesicles Urothelial cancer:2.12e-4 (favourable), Pancreatic cancer:2.53e-4 (favourable), Endometrial cancer:7.10e-4 (favourable) Expressed in all Expressed in all ovary: 40.2 SAMD1 ENSG00000141858 Sterile alpha motif domain containing 1 19 14087840-14091036 Predicted intracellular proteins Evidence at protein level HPA041662, HPA049059 Uncertain Approved Mitochondria
Cytosol Liver cancer:1.96e-5 (unfavourable), Renal cancer:7.98e-5 (unfavourable), Cervical cancer:7.41e-4 (favourable), Stomach cancer:8.31e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 32.3 SAMD4B FLJ10211, hSmaug2, MGC99832, SMGB ENSG00000179134 Sterile alpha motif domain containing 4B 19 39342396-39385710 Predicted intracellular proteins Evidence at protein level HPA016800, HPA059385 Approved Validated Cytosol Endometrial cancer:2.17e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 67.0 SAMD8 FLJ25082, SMSr ENSG00000156671 Sterile alpha motif domain containing 8 10 75099586-75182123 Predicted membrane proteins Evidence at protein level HPA044402 Supported Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 43.2 SAMHD1 AGS5, HDDC1, Mg11, MOP-5, SBBI88 ENSG00000101347 SAM domain and HD domain 1 20 36890229-36951843 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047072 Supported Supported Nucleoplasm
Plasma membrane Renal cancer:5.12e-4 (unfavourable) Expressed in all Expressed in all spleen: 135.3 SAMM50 CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W ENSG00000100347 SAMM50 sorting and assembly machinery component 22 43955421-44010531 Predicted intracellular proteins, Transporters Evidence at protein level HPA034537 Supported Validated Mitochondria Renal cancer:4.43e-8 (favourable), Endometrial cancer:2.63e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 237.7 SAP130 FLJ12761 ENSG00000136715 Sin3A-associated protein, 130kDa 2 127941217-128028120 Predicted intracellular proteins Evidence at protein level HPA034664 Supported Nuclear speckles Liver cancer:7.89e-4 (unfavourable) Expressed in all Expressed in all testis: 86.7 SAP18 2HOR0202, MGC27131, SAP18p ENSG00000150459 Sin3A-associated protein, 18kDa 13 21140514-21149084 Predicted intracellular proteins, Transporters Evidence at protein level HPA011352, CAB012273 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 256.3 SAP30 ENSG00000164105 Sin3A-associated protein, 30kDa 4 173369969-173377532 Predicted secreted proteins Evidence at protein level CAB022627, HPA059012 Supported Supported Nucleoplasm Renal cancer:1.54e-7 (unfavourable), Liver cancer:1.24e-6 (unfavourable) Expressed in all Expressed in all testis: 34.7 SAP30BP HCNGP, HTRG, HTRP ENSG00000161526 SAP30 binding protein 17 75667116-75708062 Predicted intracellular proteins Evidence at protein level HPA042382, HPA052943 Supported Validated Nucleoplasm Liver cancer:4.71e-5 (unfavourable), Renal cancer:1.98e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.1 SAR1A SAR1, Sara, SARA1 ENSG00000079332 Secretion associated, Ras related GTPase 1A 10 70147289-70170523 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006923, CAB022545, HPA048368 Supported Supported Endoplasmic reticulum Head and neck cancer:7.00e-5 (unfavourable), Liver cancer:4.04e-4 (unfavourable) Expressed in all Expressed in all placenta: 115.5 SAR1B SARA2 ENSG00000152700 Secretion associated, Ras related GTPase 1B 5 134601144-134649271 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006923, HPA048368 Supported Approved Endoplasmic reticulum Liver cancer:6.59e-4 (favourable), Endometrial cancer:7.11e-4 (favourable) Expressed in all Expressed in all testis: 117.9 SARAF MGC8721, TMEM66 ENSG00000133872 Store-operated calcium entry-associated regulatory factor 8 30063012-30083208 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA040400 Supported Endoplasmic reticulum
Rods & Rings Lung cancer:5.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 287.8 SARNP CIP29, Hcc-1, THO1 ENSG00000205323 SAP domain containing ribonucleoprotein 12 55752463-55817756 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030902, HPA030903 Supported Supported Nuclear speckles Mixed Expressed in all testis: 91.7 SARS SERS ENSG00000031698 Seryl-tRNA synthetase 1 109213918-109238169 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA016939, HPA064668 Uncertain Validated Cytosol Liver cancer:6.13e-5 (unfavourable), Head and neck cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 240.2 SARS2 FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS ENSG00000104835 Seryl-tRNA synthetase 2, mitochondrial 19 38915266-38930896 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA052730, HPA056957 Approved Expressed in all Expressed in all thyroid gland: 8.9 SART1 Ara1, SNRNP110, Snu66 ENSG00000175467 Squamous cell carcinoma antigen recognized by T cells 1 11 65961689-65979828 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031188, HPA031189, HPA031190 Supported Validated Nuclear speckles
Golgi apparatus Expressed in all Expressed in all spleen: 32.9 SART3 KIAA0156, p110, RP11-13G14, TIP110 ENSG00000075856 Squamous cell carcinoma antigen recognized by T cells 3 12 108522580-108561400 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044322 Approved Liver cancer:6.32e-6 (unfavourable), Melanoma:8.74e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 33.3 SAT1 SAT, SSAT ENSG00000130066 Spermidine/spermine N1-acetyltransferase 1 X 23783173-23786226 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB047343, HPA055312 Approved Endometrial cancer:2.87e-4 (favourable) Expressed in all Expressed in all thyroid gland: 1264.0 SAT2 SSAT2 ENSG00000141504 Spermidine/spermine N1-acetyltransferase family member 2 17 7626234-7627876 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022136, HPA057096 Supported Endometrial cancer:8.76e-6 (favourable), Pancreatic cancer:6.05e-5 (favourable), Lung cancer:6.71e-4 (favourable) Expressed in all Expressed in all duodenum: 93.5 SATB1 ENSG00000182568 SATB homeobox 1 3 18345387-18445588 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA051769, CAB056144 Supported Supported Nucleoplasm
Nuclear bodies Renal cancer:1.96e-7 (favourable), Pancreatic cancer:8.97e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 75.1 SAV1 salvador, WW45, WWP4 ENSG00000151748 Salvador family WW domain containing protein 1 14 50632058-50668331 Predicted intracellular proteins Evidence at protein level HPA001808 Approved Supported Cytosol Renal cancer:3.83e-6 (favourable), Breast cancer:2.92e-5 (favourable) Expressed in all Expressed in all thyroid gland: 58.1 SBDS CGI-97, FLJ10917, SDS, SWDS ENSG00000126524 Shwachman-Bodian-Diamond syndrome 7 66987677-66995601 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028891 Approved Supported Nucleus
Cytosol Breast cancer:1.49e-4 (unfavourable), Head and neck cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 238.7 SBF1 DENND7A, MTMR5 ENSG00000100241 SET binding factor 1 22 50445000-50475024 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA065538 Approved Endoplasmic reticulum
Vesicles Head and neck cancer:3.46e-5 (favourable) Expressed in all Expressed in all testis: 84.3 SBF2 CMT4B2, DENND7B, KIAA1766, MTMR13 ENSG00000133812 SET binding factor 2 11 9778667-10294207 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050933 Uncertain Approved Nucleoplasm
Intermediate filaments
Cytosol Renal cancer:3.66e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 38.3 SBNO1 FLJ10701, FLJ10833, MOP3, Sno ENSG00000139697 Strawberry notch homolog 1 (Drosophila) 12 123289109-123364843 Predicted intracellular proteins Evidence at protein level HPA042388 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 125.8 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase 11 121292453-121308694 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA066283, HPA070248 Approved Approved Nucleoplasm
Endoplasmic reticulum
Plasma membrane
Cytosol Renal cancer:1.07e-7 (favourable), Head and neck cancer:3.30e-4 (unfavourable), Melanoma:3.98e-4 (unfavourable) Expressed in all Expressed in all liver: 193.1 SCAF1 FLJ00034, SR-A1 ENSG00000126461 SR-related CTD-associated factor 1 19 49642125-49658642 Predicted intracellular proteins Evidence at protein level HPA046828, HPA054593 Approved Approved Nucleoplasm
Cytosol Colorectal cancer:9.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 51.8 SCAF11 CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP ENSG00000139218 SR-related CTD-associated factor 11 12 45919131-45992120 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038862, HPA045456, HPA046345 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 85.0 SCAF4 DKFZp434E098, KIAA1172, SFRS15, SRA4 ENSG00000156304 SR-related CTD-associated factor 4 21 31671033-31732075 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018319, HPA018668, HPA021504, HPA028807 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 28.4 SCAF8 KIAA1116, RBM16 ENSG00000213079 SR-related CTD-associated factor 8 6 154733325-154834244 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035601, HPA035602 Supported Validated Nucleoplasm Ovarian cancer:6.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 44.4 SCAMP1 SCAMP37 ENSG00000085365 Secretory carrier membrane protein 1 5 78360583-78479071 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044753 Approved Nucleoplasm
Vesicles
Cell Junctions Renal cancer:1.92e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 69.4 SCAMP2 ENSG00000140497 Secretory carrier membrane protein 2 15 74843730-74873365 Predicted membrane proteins Evidence at protein level HPA014699, HPA019194 Approved Supported Golgi apparatus
Vesicles Renal cancer:1.12e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 126.3 SCAMP3 C1orf3 ENSG00000116521 Secretory carrier membrane protein 3 1 155255979-155262430 Predicted membrane proteins Evidence at protein level HPA071167 Supported Vesicles Liver cancer:2.92e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 46.1 SCAMP4 FLJ33847 ENSG00000227500 Secretory carrier membrane protein 4 19 1905214-1926013 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043284 Approved Approved Golgi apparatus
Vesicles
Lipid droplets
Plasma membrane Endometrial cancer:4.40e-6 (favourable), Liver cancer:1.92e-5 (unfavourable), Renal cancer:3.56e-4 (favourable) Expressed in all Expressed in all fallopian tube: 58.6 SCAND1 RAZ1, SDP1 ENSG00000171222 SCAN domain containing 1 20 35953617-35959472 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047138 Approved Nucleus
Actin filaments
Cytosol Expressed in all Expressed in all duodenum: 30.2 SCAP KIAA0199 ENSG00000114650 SREBF chaperone 3 47413694-47477126 Predicted membrane proteins Evidence at protein level HPA004713 Approved Renal cancer:4.33e-5 (favourable), Pancreatic cancer:7.14e-4 (favourable) Expressed in all Expressed in all adrenal gland: 67.3 SCAPER Zfp291, ZNF291 ENSG00000140386 S-phase cyclin A-associated protein in the ER 15 76347904-76905444 Predicted intracellular proteins Evidence at protein level HPA046253, HPA061180 Approved Supported Nucleus
Cytosol Renal cancer:2.69e-9 (favourable) Expressed in all Expressed in all testis: 38.2 SCARB2 CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII ENSG00000138760 Scavenger receptor class B, member 2 4 76158737-76213893 Disease related genes, Predicted membrane proteins Evidence at protein level CAB015415, HPA018014 Supported Approved Cytosol Breast cancer:2.82e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 180.4 SCCPDH CGI-49, NET11 ENSG00000143653 Saccharopine dehydrogenase (putative) 1 246724047-246768137 Predicted membrane proteins Evidence at protein level HPA050775 Uncertain Approved Vesicles Expressed in all Expressed in all testis: 240.1 SCD FADS5, SCDOS ENSG00000099194 Stearoyl-CoA desaturase (delta-9-desaturase) 10 100347124-100364834 Enzymes, Predicted membrane proteins Evidence at protein level HPA012107, HPA063921 Uncertain Validated Endoplasmic reticulum Renal cancer:7.56e-5 (unfavourable), Urothelial cancer:7.79e-5 (unfavourable) Expressed in all Expressed in all adipose tissue: 1252.9 SCFD1 C14orf163, KIAA0917, RA410, SLY1, STXBP1L2 ENSG00000092108 Sec1 family domain containing 1 14 30622112-30735812 Predicted intracellular proteins Evidence at protein level HPA003579 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 72.8 SCFD2 FLJ39514, STXBP1L1 ENSG00000184178 Sec1 family domain containing 2 4 52872982-53366075 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036526, HPA036527 Supported Approved Nucleus Renal cancer:3.81e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 14.7 SCLY SCL ENSG00000132330 Selenocysteine lyase 2 238060889-238099413 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055760 Uncertain Approved Golgi apparatus Not detected Expressed in all testis: 12.8 SCMH1 Scml3 ENSG00000010803 Sex comb on midleg homolog 1 (Drosophila) 1 41027200-41242154 Predicted intracellular proteins Evidence at protein level HPA048898, HPA053292 Supported Nucleoplasm
Nuclear bodies Liver cancer:3.82e-4 (unfavourable), Urothelial cancer:5.80e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 55.0 SCML1 ENSG00000047634 Sex comb on midleg-like 1 (Drosophila) X 17737449-17754988 Predicted intracellular proteins Evidence at protein level HPA035270, HPA035271, HPA061397 Supported Approved Nucleus Expressed in all Expressed in all testis: 54.0 SCNM1 MGC3180 ENSG00000163156 Sodium channel modifier 1 1 151156664-151170297 Predicted intracellular proteins Evidence at protein level HPA052439, HPA054324 Uncertain Approved Nucleus Renal cancer:2.17e-13 (unfavourable), Ovarian cancer:1.23e-4 (favourable) Expressed in all Expressed in all lymph node: 45.9 SCO1 SCOD1 ENSG00000133028 SCO1 cytochrome c oxidase assembly protein 17 10672474-10698375 Disease related genes, Predicted membrane proteins Evidence at protein level HPA021565, HPA021579 Approved Renal cancer:9.69e-7 (favourable), Thyroid cancer:7.44e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 22.5 SCO2 MYP6, SCO1L ENSG00000130489 SCO2 cytochrome c oxidase assembly protein 22 50523568-50526439 Disease related genes, Predicted membrane proteins Evidence at protein level HPA056254 Approved Supported Nucleoplasm
Mitochondria Renal cancer:1.67e-4 (unfavourable) Expressed in all Expressed in all appendix: 50.4 SCOC HRIHFB2072, SCOCO ENSG00000153130 Short coiled-coil protein 4 140257286-140385726 Predicted intracellular proteins Evidence at protein level HPA061198, HPA070321 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:4.82e-12 (favourable) Expressed in all Expressed in all cerebral cortex: 188.5 SCP2 ENSG00000116171 Sterol carrier protein 2 1 52927229-53051703 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027101, HPA027135, HPA027317 Supported Validated Peroxisomes Renal cancer:7.85e-8 (favourable), Colorectal cancer:7.05e-5 (favourable) Expressed in all Expressed in all liver: 569.5 SCPEP1 RISC ENSG00000121064 Serine carboxypeptidase 1 17 56978105-57006768 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039102, HPA057200 Approved Approved Golgi apparatus Liver cancer:1.96e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 610.1 SCRIB KIAA0147, SCRB1, Vartul ENSG00000180900 Scribbled planar cell polarity protein 8 143790920-143815379 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB015463, CAB022081, HPA023557, HPA064312 Supported Validated Nucleoplasm
Plasma membrane
Cell Junctions
Rods & Rings Expressed in all Expressed in all skin: 22.0 SCRN2 ENSG00000141295 Secernin 2 17 47837692-47841333 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022934, HPA023434 Supported Supported Nucleoplasm
Golgi apparatus Liver cancer:3.86e-4 (favourable), Urothelial cancer:5.83e-4 (favourable) Expressed in all Expressed in all adipose tissue: 84.2 SCRN3 FLJ23142 ENSG00000144306 Secernin 3 2 174395730-174429575 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034689, HPA034690 Approved Approved Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 47.7 SCYL1 GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP ENSG00000142186 SCY1-like, kinase-like 1 11 65525077-65538704 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015015 Uncertain Supported Cytosol Expressed in all Expressed in all thyroid gland: 55.0 SCYL2 CVAK104, KIAA1360 ENSG00000136021 SCY1-like, kinase-like 2 12 100267140-100341724 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021050 Approved Expressed in all Expressed in all parathyroid gland: 41.1 SCYL3 PACE-1, PACE1 ENSG00000000457 SCY1-like, kinase-like 3 1 169849631-169894267 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005624 Approved Uncertain Nuclear bodies
Microtubules Urothelial cancer:8.85e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 44.0 SDAD1 FLJ10498 ENSG00000198301 SDA1 domain containing 1 4 75940950-75990962 Predicted intracellular proteins Evidence at protein level HPA035949 Uncertain Supported Nucleus
Nucleoli Liver cancer:1.32e-4 (unfavourable), Renal cancer:2.13e-4 (favourable) Expressed in all Expressed in all testis: 37.9 SDC2 CD362, fibroglycan, HSPG, HSPG1, SYND2 ENSG00000169439 Syndecan 2 8 96493351-96611780 CD markers, Predicted membrane proteins Evidence at protein level CAB025123, HPA044416 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 708.5 SDC3 N-syndecan, SYND3 ENSG00000162512 Syndecan 3 1 30869467-30908761 Predicted membrane proteins Evidence at protein level HPA017087, CAB025786, HPA048085 Approved Approved Nucleoplasm
Mitochondria Renal cancer:1.71e-4 (unfavourable), Melanoma:2.36e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 136.8 SDC4 amphiglycan, ryudocan, SYND4 ENSG00000124145 Syndecan 4 20 45325288-45348424 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level HPA005716, CAB013240 Supported Approved Golgi apparatus
Plasma membrane Renal cancer:2.44e-7 (favourable), Thyroid cancer:2.67e-4 (favourable), Pancreatic cancer:4.20e-4 (unfavourable) Expressed in all Expressed in all lung: 250.5 SDCBP SYCL ENSG00000137575 Syndecan binding protein (syntenin) 8 58552924-58582860 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012245, HPA023840 Approved Approved Nucleoplasm
Nuclear membrane
Cytosol Expressed in all Expressed in all placenta: 362.0 SDCCAG3 NY-CO-3 ENSG00000165689 Serologically defined colon cancer antigen 3 9 136401922-136410609 Predicted intracellular proteins Evidence at protein level HPA029303 Approved Renal cancer:8.50e-5 (unfavourable) Expressed in all Expressed in all testis: 36.3 SDCCAG8 BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7 ENSG00000054282 Serologically defined colon cancer antigen 8 1 243256034-243500092 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA025737, HPA044477, HPA072495 Approved Validated Centrosome Expressed in all Expressed in all thyroid gland: 23.9 SDE2 C1orf55, FLJ35382 ENSG00000143751 SDE2 telomere maintenance homolog (S. pombe) 1 225982702-225999331 Predicted intracellular proteins Evidence at protein level HPA028467, HPA031255, HPA031256 Approved Approved Nuclear speckles
Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all thyroid gland: 21.0 SDF2 ENSG00000132581 Stromal cell-derived factor 2 17 28648356-28662189 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042799 Approved Vesicles Liver cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 27.9 SDF2L1 AP000553.C22.4, OTTHUMT00000075032 ENSG00000128228 Stromal cell-derived factor 2-like 1 22 21642261-21644298 Predicted secreted proteins Evidence at protein level HPA005638 Approved Endometrial cancer:4.98e-5 (favourable) Expressed in all Expressed in all thyroid gland: 45.2 SDF4 Cab45 ENSG00000078808 Stromal cell derived factor 4 1 1216908-1232031 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011249, CAB015227 Supported Validated Golgi apparatus Cervical cancer:5.89e-4 (unfavourable) Expressed in all Expressed in all small intestine: 131.3 SDHA FP, SDH2, SDHF ENSG00000073578 Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 5 218241-256700 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB034929, HPA041981, HPA064582 Supported Validated Mitochondria Renal cancer:9.53e-8 (favourable), Breast cancer:6.00e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 249.5 SDHAF1 LYRM8 ENSG00000205138 Succinate dehydrogenase complex assembly factor 1 19 35995199-35996315 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064277 Approved Mitochondria Renal cancer:2.11e-4 (favourable) Expressed in all Expressed in all duodenum: 14.2 SDHAF2 C11orf79, FLJ20487, PGL2, SDH5 ENSG00000167985 Succinate dehydrogenase complex assembly factor 2 11 61430042-61447529 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039464, HPA039732 Supported Supported Nucleoli
Mitochondria
Cytosol Expressed in all Expressed in all fallopian tube: 35.7 SDHAF3 ACN9, DC11, Sdh7 ENSG00000196636 Succinate dehydrogenase complex assembly factor 3 7 97116590-97181763 Predicted intracellular proteins Evidence at protein level HPA020523 Approved Approved Microtubules
Mitochondria Expressed in all Expressed in all testis: 15.1 SDHAF4 C6orf57, Sdh8 ENSG00000154079 Succinate dehydrogenase complex assembly factor 4 6 70566917-70589569 Predicted secreted proteins Evidence at protein level HPA031824 Supported Approved Nucleus
Mitochondria Renal cancer:1.95e-5 (favourable) Expressed in all Expressed in all fallopian tube: 17.2 SDHB SDH, SDH1 ENSG00000117118 Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1 17018722-17054170 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002868, CAB009822, CAB068233, CAB068234, CAB068235 Supported Supported Nucleoplasm
Plasma membrane
Mitochondria Renal cancer:2.93e-7 (favourable) Expressed in all Expressed in all kidney: 213.3 SDHC CYB560, PGL3 ENSG00000143252 Succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1 161314257-161375340 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.20e-4 (favourable) Expressed in all Expressed in all kidney: 187.3 SDHD PGL, PGL1 ENSG00000204370 Succinate dehydrogenase complex, subunit D, integral membrane protein 11 112086773-112120013 Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA045727 Approved Renal cancer:1.99e-10 (favourable) Expressed in all Expressed in all kidney: 303.5 SDPR cavin-2, CAVIN2, PS-p68, SDR ENSG00000168497 Serum deprivation response 2 191834302-191847255 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039325, HPA062122 Supported Supported Plasma membrane
Cytosol Renal cancer:8.45e-5 (favourable), Stomach cancer:3.69e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 165.5 SDR39U1 C14orf124, HCDI ENSG00000100445 Short chain dehydrogenase/reductase family 39U, member 1 14 24439766-24442905 Predicted intracellular proteins Evidence at protein level HPA044294 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:2.34e-4 (favourable) Expressed in all Expressed in all adrenal gland: 43.0 SEC11A SEC11L1, sid2895, SPC18, SPCS4A ENSG00000140612 SEC11 homolog A, signal peptidase complex subunit 15 84669538-84716716 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047533 Approved Nuclear membrane
Golgi apparatus Endometrial cancer:1.94e-5 (favourable), Head and neck cancer:5.99e-5 (unfavourable), Thyroid cancer:2.95e-4 (favourable) Expressed in all Expressed in all thyroid gland: 211.4 SEC11C SEC11L3, SPC21, SPCS4C ENSG00000166562 SEC11 homolog C, signal peptidase complex subunit 18 59139477-59158836 Enzymes, Predicted membrane proteins Evidence at protein level HPA026816, HPA047533 Approved Approved Nuclear membrane
Golgi apparatus Expressed in all Expressed in all prostate: 275.4 SEC13 D3S1231E, npp-20, SEC13L1, SEC13R ENSG00000157020 SEC13 homolog, nuclear pore and COPII coat complex component 3 10293131-10321178 Predicted intracellular proteins, Transporters Evidence at protein level HPA035292, HPA057943 Approved Supported Nucleoplasm
Vesicles Liver cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 119.1 SEC14L1 PRELID4A, SEC14L ENSG00000129657 SEC14-like lipid binding 1 17 77086716-77217101 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021463, HPA028703 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all placenta: 118.5 SEC16A KIAA0310, p250, Sec16L ENSG00000148396 SEC16 homolog A, endoplasmic reticulum export factor 9 136440096-136483759 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005684 Supported Supported Endoplasmic reticulum
Golgi apparatus Endometrial cancer:1.30e-6 (favourable), Renal cancer:4.47e-4 (favourable) Expressed in all Expressed in all stomach: 26.6 SEC22A SEC22L2 ENSG00000121542 SEC22 homolog A, vesicle trafficking protein 3 123201927-123274130 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all testis: 48.4 SEC22B ERS-24, sec22b, SEC22L1 ENSG00000265808 SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) 1 120150898-120176515 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:3.34e-4 (unfavourable), Ovarian cancer:4.58e-4 (favourable) Expressed in all Expressed in all epididymis: 42.7 SEC22C MGC13261, MGC5373, SEC22L3 ENSG00000093183 SEC22 homolog C, vesicle trafficking protein 3 42547969-42601080 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA055594 Approved Golgi apparatus Renal cancer:1.35e-7 (favourable), Liver cancer:3.04e-5 (unfavourable) Expressed in all Expressed in all prostate: 66.4 SEC23A ENSG00000100934 Sec23 homolog A, COPII coat complex component 14 39031919-39109646 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043806, HPA069974 Uncertain Approved Nucleoplasm
Vesicles Renal cancer:1.69e-4 (unfavourable), Stomach cancer:2.94e-4 (unfavourable), Colorectal cancer:3.56e-4 (favourable), Cervical cancer:5.75e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 139.3 SEC23B CDA-II, CDAII, CDAN2, HEMPAS ENSG00000101310 Sec23 homolog B, COPII coat complex component 20 18507493-18561415 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008216, HPA069974 Uncertain Supported Vesicles Endometrial cancer:8.25e-4 (favourable) Expressed in all Expressed in all thyroid gland: 85.5 SEC23IP p125 ENSG00000107651 SEC23 interacting protein 10 119892711-119944658 Predicted intracellular proteins Evidence at protein level HPA038403, HPA043305 Approved Validated Vesicles Expressed in all Expressed in all smooth muscle: 30.1 SEC24A ENSG00000113615 SEC24 homolog A, COPII coat complex component 5 134648789-134727823 Predicted intracellular proteins Evidence at protein level HPA038901, HPA056825 Approved Approved Nucleoli fibrillar center
Vesicles Cervical cancer:3.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.3 SEC24B ENSG00000138802 SEC24 homolog B, COPII coat complex component 4 109433772-109540896 Predicted intracellular proteins Evidence at protein level HPA038181 Approved Approved Nucleus
Vesicles Renal cancer:2.33e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 42.0 SEC24C KIAA0079 ENSG00000176986 SEC24 homolog C, COPII coat complex component 10 73744384-73772161 Predicted intracellular proteins Evidence at protein level HPA040196, HPA040213 Supported Supported Vesicles Expressed in all Expressed in all parathyroid gland: 82.7 SEC31A ABP125, ABP130, KIAA0905, SEC31L1 ENSG00000138674 SEC31 homolog A, COPII coat complex component 4 82818661-82901166 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA005457 Approved Supported Vesicles
Cytosol Urothelial cancer:2.69e-4 (unfavourable), Liver cancer:3.32e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 279.9 SEC61A1 ENSG00000058262 Sec61 translocon alpha 1 subunit 3 128051641-128071683 Predicted membrane proteins, Transporters Evidence at protein level CAB022076 Supported Endoplasmic reticulum Renal cancer:6.84e-9 (unfavourable), Liver cancer:1.07e-6 (unfavourable), Endometrial cancer:7.82e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 217.0 SEC61B ENSG00000106803 Sec61 translocon beta subunit 9 99222064-99230615 Predicted membrane proteins, Transporters Evidence at protein level HPA049407 Approved Validated Endoplasmic reticulum Endometrial cancer:1.26e-5 (favourable) Expressed in all Expressed in all epididymis: 333.0 SEC61G SSS1 ENSG00000132432 Sec61 translocon gamma subunit 7 54752250-54759974 Predicted membrane proteins, Transporters Evidence at protein level HPA053196 Uncertain Renal cancer:6.60e-8 (unfavourable), Head and neck cancer:4.64e-7 (unfavourable), Liver cancer:3.85e-6 (unfavourable) Expressed in all Expressed in all epididymis: 401.2 SEC62 Dtrp1, HTP1, TLOC1 ENSG00000008952 SEC62 homolog, preprotein translocation factor 3 169966635-169998373 Predicted membrane proteins Evidence at protein level HPA014059, HPA061450 Approved Approved Endoplasmic reticulum
Intermediate filaments Expressed in all Expressed in all thyroid gland: 202.4 SEC63 DNAJC23, ERdj2, PRO2507, SEC63L ENSG00000025796 SEC63 homolog, protein translocation regulator 6 107867756-107958189 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA053295, HPA060535 Supported Supported Endoplasmic reticulum Breast cancer:3.32e-4 (unfavourable), Cervical cancer:4.01e-4 (unfavourable), Renal cancer:6.16e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 87.1 SECISBP2 ENSG00000187742 SECIS binding protein 2 9 89318506-89359662 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA044314, HPA054905 Approved Supported Nucleoplasm Renal cancer:8.98e-9 (favourable) Expressed in all Expressed in all testis: 127.2 SECISBP2L KIAA0256 ENSG00000138593 SECIS binding protein 2-like 15 48988476-49046563 Predicted intracellular proteins Evidence at protein level HPA039875 Approved Approved Nucleoplasm Renal cancer:5.65e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 83.3 SEH1L SEC13L, Seh1, SEH1A, SEH1B ENSG00000085415 SEH1-like nucleoporin 18 12947133-12987536 Predicted intracellular proteins, Transporters Evidence at protein level HPA039964 Uncertain Expressed in all Expressed in all cerebral cortex: 34.0 SEL1L IBD2, SEL1L1 ENSG00000071537 Sel-1 suppressor of lin-12-like (C. elegans) 14 81471549-81533861 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA024267 Approved Expressed in all Expressed in all thyroid gland: 90.3 SEL1L3 KIAA0746 ENSG00000091490 Sel-1 suppressor of lin-12-like 3 (C. elegans) 4 25747427-25863760 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040045, HPA058792 Approved Validated Nucleus Urothelial cancer:4.33e-4 (favourable) Expressed in all Expressed in all lymph node: 148.5 SELENBP1 hSBP, hSP56, LPSB ENSG00000143416 Selenium binding protein 1 1 151364302-151372733 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005741, CAB008366, HPA011731 Supported Supported Nucleoli Head and neck cancer:6.63e-4 (favourable) Expressed in all Expressed in all rectum: 496.0 SELK ENSG00000113811 Selenoprotein K 3 53884410-53891988 Predicted membrane proteins Evidence at protein level HPA008196 Uncertain Approved Nucleoplasm
Cytosol Lung cancer:3.76e-4 (favourable), Endometrial cancer:7.18e-4 (favourable) Expressed in all Expressed in all epididymis: 74.5 SELM ENSG00000198832 Selenoprotein M 22 31104772-31120069 Predicted secreted proteins Evidence at protein level CAB008667, HPA019601 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.55e-6 (unfavourable) Expressed in all Expressed in all seminal vesicle: 198.4 SELO ENSG00000073169 Selenoprotein O 22 50200979-50217616 Predicted secreted proteins Evidence at protein level Urothelial cancer:8.32e-4 (favourable) Expressed in all Expressed in all skin: 9.3 SELT ENSG00000198843 Selenoprotein T 3 150602875-150630445 Predicted membrane proteins Evidence at protein level HPA039780 Approved Expressed in all Expressed in all thyroid gland: 108.8 SEMA3F Sema4, SEMAK ENSG00000001617 Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 3 50155045-50189075 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA035008 Approved Liver cancer:5.15e-4 (unfavourable) Expressed in all Expressed in all skin: 89.3 SEMA4B KIAA1745, MGC131831, SEMAC, SemC ENSG00000185033 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 15 90160604-90229679 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013372 Approved Renal cancer:3.33e-8 (unfavourable), Lung cancer:1.25e-4 (unfavourable) Expressed in all Expressed in all esophagus: 49.5 SEMA4C Semacl1, Semaf, SEMAI ENSG00000168758 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 2 96859716-96870757 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA011090 Approved Renal cancer:9.50e-7 (unfavourable), Colorectal cancer:3.53e-5 (unfavourable) Expressed in all Expressed in all placenta: 63.0 SEMA4D C9orf164, CD100, coll-4, FLJ39737, SEMAJ ENSG00000187764 Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 9 89360787-89498130 CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015662, HPA023277 Approved Supported Endoplasmic reticulum
Vesicles Urothelial cancer:4.06e-5 (favourable), Cervical cancer:4.17e-4 (favourable) Expressed in all Expressed in all lymph node: 73.3 SEMA6A HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ ENSG00000092421 Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 5 116443616-116574934 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA031265, HPA031267 Approved Supported Nucleus
Intermediate filaments Liver cancer:4.39e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 49.3 SENP2 AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2 ENSG00000163904 SUMO1/sentrin/SMT3 specific peptidase 2 3 185582496-185633551 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA029247, HPA029248 Approved Supported Cytosol Endometrial cancer:7.98e-5 (unfavourable) Expressed in all Expressed in all testis: 26.8 SENP3 DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1 ENSG00000161956 SUMO1/sentrin/SMT3 specific peptidase 3 17 7561875-7571969 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060290 Supported Supported Nucleus
Nucleoli Pancreatic cancer:6.22e-5 (favourable) Expressed in all Expressed in all testis: 57.1 SENP5 MGC27076 ENSG00000119231 SUMO1/sentrin specific peptidase 5 3 196867856-196934714 Enzymes, Predicted intracellular proteins Evidence at protein level Renal cancer:2.14e-5 (unfavourable), Endometrial cancer:4.04e-4 (unfavourable), Liver cancer:4.15e-4 (unfavourable) Expressed in all Expressed in all testis: 37.5 SENP6 KIAA0797, SUSP1 ENSG00000112701 SUMO1/sentrin specific peptidase 6 6 75601509-75718278 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024376 Approved Supported Nucleoplasm
Cytosol Thyroid cancer:2.83e-5 (unfavourable), Renal cancer:6.09e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.9 SENP7 ENSG00000138468 SUMO1/sentrin specific peptidase 7 3 101324205-101513241 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027259 Approved Approved Nucleoplasm
Cytosol Head and neck cancer:4.23e-4 (favourable) Expressed in all Expressed in all endometrium: 44.0 SEP15 ENSG00000183291 15 kDa selenoprotein 1 86862445-86914424 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA054937 Approved Nucleoli
Cytosol Liver cancer:1.98e-5 (unfavourable), Colorectal cancer:6.53e-4 (favourable), Head and neck cancer:8.17e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 360.2 SEPHS1 SPS, SPS1 ENSG00000086475 Selenophosphate synthetase 1 10 13317424-13348298 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037645 Uncertain Uncertain Nucleoplasm Liver cancer:2.16e-7 (unfavourable), Pancreatic cancer:3.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 92.5 SEPHS2 SPS2, SPS2b ENSG00000179918 Selenophosphate synthetase 2 16 30444381-30446181 Predicted intracellular proteins Evidence at protein level HPA047931 Approved Approved Nucleoplasm Renal cancer:4.35e-8 (favourable) Expressed in all Expressed in all liver: 164.0 SEPN1 MDRS1, RSMD1, RSS, selN ENSG00000162430 Selenoprotein N, 1 1 25800176-25818224 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA058076 Approved Supported Cytosol Liver cancer:3.40e-5 (unfavourable), Endometrial cancer:2.23e-4 (favourable) Expressed in all Expressed in all smooth muscle: 80.2 SEPP1 SelP, SeP, SEPP ENSG00000250722 Selenoprotein P, plasma, 1 5 42799880-42887392 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA036287 Approved Approved Nucleus
Golgi apparatus Renal cancer:6.97e-6 (favourable) Expressed in all Expressed in all liver: 2937.1 SEPSECS SLA, SLA/LP ENSG00000109618 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 4 25120014-25160442 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA070409 Approved Vesicles Expressed in all Expressed in all liver: 16.7 SEPT11 FLJ10849 ENSG00000138758 Septin 11 4 76949703-77040384 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003459, HPA005665 Approved Liver cancer:1.70e-5 (unfavourable), Renal cancer:2.40e-4 (favourable) Expressed in all Expressed in all placenta: 119.4 SEPT2 DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3 ENSG00000168385 Septin 2 2 241315100-241354027 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017190, HPA018481 Supported Supported Nucleus
Actin filaments
Cytosol Liver cancer:3.66e-4 (unfavourable), Glioma:4.32e-4 (favourable) Expressed in all Expressed in all thyroid gland: 368.1 SEPT5 H5, HCDCREL-1, PNUTL1 ENSG00000184702 Septin 5 22 19714464-19724772 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB016120, HPA029095, HPA063885 Supported Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:6.87e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 378.7 SEPT7 CDC10, CDC3, SEPT7A ENSG00000122545 Septin 7 7 35800932-35907105 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023309, HPA029524 Supported Approved Actin filaments
Microtubules Liver cancer:2.37e-4 (unfavourable), Renal cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 431.7 SEPT8 KIAA0202, SEP2 ENSG00000164402 Septin 8 5 132750817-132807241 Predicted intracellular proteins Evidence at protein level HPA005665, HPA036534 Approved Uncertain Actin filaments
Cytosol Renal cancer:6.98e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 281.0 SEPT9 AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SeptD1 ENSG00000184640 Septin 9 17 77280569-77500596 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042564, HPA050627 Approved Validated Actin filaments Liver cancer:1.61e-5 (unfavourable) Expressed in all Expressed in all lymph node: 272.5 SEPW1 selW ENSG00000178980 Selenoprotein W, 1 19 47778572-47784686 Predicted intracellular proteins Evidence at protein level Lung cancer:5.44e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 442.1 SERAC1 FLJ14917 ENSG00000122335 Serine active site containing 1 6 158109515-158168270 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA025715, HPA025716 Approved Expressed in all Expressed in all testis: 16.5 SERBP1 CGI-55, CHD3IP, DKFZP564M2423, HABP4L, PAI-RBP1, PAIRBP1 ENSG00000142864 SERPINE1 mRNA binding protein 1 1 67407810-67430415 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020559, CAB026297 Supported Validated Cytosol Liver cancer:1.36e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 290.1 SERF2 4F5REL, FAM2C, H4F5rel, HsT17089 ENSG00000140264 Small EDRK-rich factor 2 15 43777087-43802589 Predicted intracellular proteins Evidence at protein level HPA056613 Uncertain Nucleus
Nucleoli Endometrial cancer:5.33e-4 (favourable) Expressed in all Expressed in all epididymis: 896.5 SERGEF DelGEF, Gnefr ENSG00000129158 Secretion regulating guanine nucleotide exchange factor 11 17788048-18013162 Predicted intracellular proteins Evidence at protein level HPA037811, HPA037812, HPA074086 Supported Validated Nucleoplasm
Vesicles
Cytosol Glioma:7.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 52.7 SERINC1 KIAA1253, TDE1L, TDE2, TMS-2 ENSG00000111897 Serine incorporator 1 6 122443354-122471822 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA035738, HPA035739 Uncertain Approved Cytosol Expressed in all Expressed in all cerebral cortex: 617.2 SERINC3 AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1 ENSG00000132824 Serine incorporator 3 20 44496221-44522109 Predicted membrane proteins Evidence at protein level HPA048116 Uncertain Cervical cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all testis: 200.8 SERP1 FLJ43424, RAMP4 ENSG00000120742 Stress-associated endoplasmic reticulum protein 1 3 150541994-150603228 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038970 Approved Approved Endoplasmic reticulum Pancreatic cancer:1.03e-5 (unfavourable) Expressed in all Expressed in all epididymis: 179.5 SERPINB1 anti-elastase, EI, ELANH2, PI2 ENSG00000021355 Serpin peptidase inhibitor, clade B (ovalbumin), member 1 6 2832332-2842006 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018871, HPA052642 Supported Expressed in all Expressed in all esophagus: 466.2 SERPINB6 CAP, DFNB91, PI6, PTI ENSG00000124570 Serpin peptidase inhibitor, clade B (ovalbumin), member 6 6 2948159-2972165 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA009668, HPA012736 Supported Approved Centrosome Renal cancer:2.21e-4 (unfavourable), Ovarian cancer:4.81e-4 (favourable) Expressed in all Expressed in all testis: 254.5 SERPINF1 EPC-1, PEDF, PIG35 ENSG00000132386 Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 17 1761959-1777574 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA005825 Approved Renal cancer:1.40e-8 (unfavourable), Cervical cancer:5.49e-4 (favourable) Expressed in all Expressed in all gallbladder: 742.8 SERPING1 C1-INH, C1IN, C1NH, HAE1, HAE2 ENSG00000149131 Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 11 57597387-57614853 Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB026161, HPA048738 Supported Renal cancer:1.55e-4 (unfavourable), Ovarian cancer:8.03e-4 (favourable), Colorectal cancer:9.96e-4 (unfavourable) Expressed in all Expressed in all liver: 1365.4 SERPINH1 CBP1, CBP2, colligen, HSP47, SERPINH2 ENSG00000149257 Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 11 75562056-75572783 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB004441, HPA029198 Supported Validated Endoplasmic reticulum Renal cancer:3.22e-15 (unfavourable), Head and neck cancer:1.85e-4 (unfavourable), Cervical cancer:2.10e-4 (unfavourable) Expressed in all Expressed in all placenta: 327.0 SERTAD1 SEI1, TRIP-Br1 ENSG00000197019 SERTA domain containing 1 19 40421592-40426025 Predicted intracellular proteins Evidence at protein level HPA063323 Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all gallbladder: 19.7 SERTAD2 KIAA0127, Sei-2, TRIP-Br2 ENSG00000179833 SERTA domain containing 2 2 64631621-64751005 Predicted intracellular proteins Evidence at protein level HPA019021, HPA020904 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.70e-4 (unfavourable), Endometrial cancer:4.03e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 54.0 SERTAD3 RBT1 ENSG00000167565 SERTA domain containing 3 19 40440844-40444705 Predicted intracellular proteins Evidence at protein level HPA068262 Supported Nucleoli Expressed in all Expressed in all prostate: 39.5 SESN1 PA26, SEST1 ENSG00000080546 Sestrin 1 6 108986437-109094819 Predicted intracellular proteins Evidence at protein level HPA073659 Supported Nucleus
Nucleoli fibrillar center Head and neck cancer:6.47e-5 (favourable), Prostate cancer:2.07e-4 (favourable) Expressed in all Expressed in all testis: 78.5 SET 2PP2A, IPP2A2, PHAPII ENSG00000119335 SET nuclear proto-oncogene 9 128683424-128696400 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005232, HPA063683 Supported Supported Nucleoplasm
Lipid droplets Liver cancer:9.41e-7 (unfavourable) Expressed in all Expressed in all lymph node: 366.1 SETBP1 KIAA0437, SEB ENSG00000152217 SET binding protein 1 18 44680173-45068510 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA049022, HPA057259 Uncertain Supported Nucleus
Nuclear bodies
Cytosol Renal cancer:6.34e-8 (favourable) Mixed Expressed in all seminal vesicle: 13.8 SETD1A KIAA0339, KMT2F, Set1 ENSG00000099381 SET domain containing 1A 16 30957294-30985116 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020646, HPA058376 Supported Supported Nuclear speckles Liver cancer:8.47e-4 (unfavourable) Expressed in all Expressed in all testis: 24.7 SETD1B KIAA1076, KMT2G, Set1B ENSG00000139718 SET domain containing 1B 12 121804180-121832584 Enzymes, Predicted intracellular proteins Evidence at protein level HPA021667, HPA059412 Approved Validated Nucleoplasm Expressed in all Expressed in all endometrium: 19.0 SETD2 FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A ENSG00000181555 SET domain containing 2 3 47016429-47163967 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA042451 Approved Approved Nuclear speckles
Cytosol Renal cancer:7.99e-6 (favourable), Melanoma:8.19e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 30.5 SETD3 C14orf154, FLJ23027 ENSG00000183576 SET domain containing 3 14 99397746-99480889 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003591, HPA003639 Approved Approved Mitochondria Renal cancer:1.89e-15 (favourable), Head and neck cancer:6.46e-4 (unfavourable) Expressed in all Expressed in all testis: 153.6 SETD4 C21orf18, C21orf27 ENSG00000185917 SET domain containing 4 21 36034541-36079389 Predicted intracellular proteins Evidence at protein level HPA024073, HPA035405 Approved Approved Nuclear speckles Expressed in all Expressed in all testis: 41.7 SETD5 FLJ10707 ENSG00000168137 SET domain containing 5 3 9397615-9479240 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB017093, HPA035574 Approved Validated Nucleus
Cytosol Renal cancer:4.27e-4 (unfavourable), Liver cancer:6.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.0 SETD6 FLJ21148 ENSG00000103037 SET domain containing 6 16 58515479-58521181 Predicted intracellular proteins Evidence at protein level HPA041481, HPA053546 Uncertain Supported Nucleus
Cytosol Prostate cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.3 SETD7 KIAA1717, KMT7, SET7, SET7/9, Set9 ENSG00000145391 SET domain containing (lysine methyltransferase) 7 4 139495941-139606699 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA058111 Approved Supported Nucleoli Breast cancer:8.28e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.7 SETD8 KMT5A, PR-Set7, SET07, SET8 ENSG00000183955 SET domain containing (lysine methyltransferase) 8 12 123383773-123409358 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA064495 Supported Nucleus Liver cancer:6.21e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.1 SETDB1 ESET, KG1T, KIAA0067, KMT1E, TDRD21 ENSG00000143379 SET domain, bifurcated 1 1 150926263-150964744 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018142, HPA058484 Uncertain Validated Nucleoplasm
Cytosol Renal cancer:4.25e-4 (unfavourable), Liver cancer:8.88e-4 (unfavourable) Expressed in all Expressed in all testis: 46.1 SETMAR metnase ENSG00000170364 SET domain and mariner transposase fusion gene 3 4303304-4317567 Enzymes, Predicted intracellular proteins Evidence at protein level HPA057999 Supported Nucleoli Renal cancer:6.61e-6 (favourable), Liver cancer:2.85e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 15.9 SETX ALS4, AOA2, KIAA0625, SCAR1 ENSG00000107290 Senataxin 9 132261356-132354985 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024105, HPA057269 Approved Supported Nucleus
Cytokinetic bridge Expressed in all Expressed in all testis: 58.1 SF1 ZCCHC25, ZFM1, ZNF162 ENSG00000168066 Splicing factor 1 11 64764606-64778786 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018883 Supported Validated Nucleoplasm Liver cancer:4.85e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 146.1 SF3A1 Prp21, PRPF21, SAP114, SF3a120 ENSG00000099995 Splicing factor 3a, subunit 1, 120kDa 22 30331988-30356947 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000690, HPA030083 Supported Validated Nuclear speckles Renal cancer:1.16e-4 (favourable) Expressed in all Expressed in all testis: 88.7 SF3A2 Prp11, PRPF11, SAP62, SF3a66 ENSG00000104897 Splicing factor 3a, subunit 2, 66kDa 19 2236504-2248679 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA042843, HPA049439 Supported Approved Nucleoplasm Liver cancer:3.23e-5 (unfavourable), Renal cancer:2.07e-4 (unfavourable), Cervical cancer:7.16e-4 (favourable), Colorectal cancer:8.64e-4 (unfavourable) Expressed in all Expressed in all testis: 50.5 SF3A3 PRP9, PRPF9, SAP61, SF3a60 ENSG00000183431 Splicing factor 3a, subunit 3, 60kDa 1 37956975-37990921 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA032054, HPA032055 Supported Validated Nucleoplasm Liver cancer:2.11e-8 (unfavourable) Expressed in all Expressed in all endometrium: 35.1 SF3B1 Hsh155, Prp10, PRPF10, SAP155, SF3b155 ENSG00000115524 Splicing factor 3b, subunit 1, 155kDa 2 197389784-197435091 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA050275 Approved Validated Nuclear speckles Expressed in all Expressed in all endometrium: 345.5 SF3B2 Cus1, SAP145, SF3b1, SF3b145 ENSG00000087365 Splicing factor 3b, subunit 2, 145kDa 11 66050729-66069308 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045028 Supported Validated Nuclear speckles Renal cancer:3.51e-5 (favourable), Liver cancer:6.43e-5 (unfavourable) Expressed in all Expressed in all testis: 192.8 SF3B3 KIAA0017, RSE1, SAP130, SF3b130 ENSG00000189091 Splicing factor 3b, subunit 3, 130kDa 16 70523788-70577670 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041134, HPA042986 Supported Supported Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 40.9 SF3B4 Hsh49, SAP49, SF3b49 ENSG00000143368 Splicing factor 3b, subunit 4, 49kDa 1 149923317-149928344 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028578, HPA064660 Approved Approved Nuclear speckles Renal cancer:1.74e-7 (unfavourable), Liver cancer:1.54e-5 (unfavourable) Expressed in all Expressed in all testis: 71.6 SF3B5 MGC3133, SF3b10, Ysf3 ENSG00000169976 Splicing factor 3b, subunit 5, 10kDa 6 144094881-144095573 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054408 Approved Validated Nucleoplasm Expressed in all Expressed in all fallopian tube: 201.6 SF3B6 CGI-110, Ht006, P14, SAP14a, SF3B14a ENSG00000115128 Splicing factor 3b, subunit 6, 14kDa 2 24067584-24076443 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034829, HPA034830 Supported Supported Nucleoplasm Liver cancer:5.57e-5 (unfavourable), Renal cancer:1.74e-4 (unfavourable), Pancreatic cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 152.6 SFPQ PPP1R140, PSF ENSG00000116560 Splicing factor proline/glutamine-rich 1 35176378-35193148 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009886, HPA047513, HPA054689 Supported Validated Nucleoplasm Liver cancer:7.91e-13 (unfavourable), Breast cancer:9.56e-5 (favourable) Expressed in all Expressed in all bone marrow: 135.7 SFR1 bA373N18.1, C10orf78, FLJ41960, MEI5, MEIR5 ENSG00000156384 SWI5-dependent homologous recombination repair protein 1 10 104122058-104126385 Predicted intracellular proteins Evidence at protein level HPA039617 Uncertain Liver cancer:2.59e-5 (unfavourable), Renal cancer:2.23e-4 (unfavourable) Expressed in all Expressed in all testis: 32.9 SFSWAP SFRS8, SWAP ENSG00000061936 Splicing factor, suppressor of white-apricot family 12 131711081-131799737 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039362, HPA040063 Approved Approved Nucleus
Plasma membrane
Cytosol Renal cancer:3.33e-8 (unfavourable), Melanoma:1.10e-4 (unfavourable) Expressed in all Expressed in all skin: 18.1 SFT2D1 C6orf83, MGC19825, pRGR1 ENSG00000198818 SFT2 domain containing 1 6 166319728-166342591 Predicted membrane proteins Evidence at protein level HPA014677 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:2.19e-5 (unfavourable), Renal cancer:3.59e-4 (unfavourable), Thyroid cancer:5.90e-4 (favourable), Head and neck cancer:7.47e-4 (unfavourable) Expressed in all Expressed in all prostate: 77.5 SFXN1 FLJ12876 ENSG00000164466 Sideroflexin 1 5 175477062-175529742 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019543, HPA063745 Uncertain Validated Mitochondria Expressed in all Expressed in all liver: 51.5 SFXN3 SFX3 ENSG00000107819 Sideroflexin 3 10 101031234-101041244 Predicted membrane proteins Evidence at protein level HPA008028, HPA048105 Approved Validated Mitochondria Head and neck cancer:3.79e-4 (unfavourable), Renal cancer:4.94e-4 (unfavourable) Expressed in all Expressed in all small intestine: 42.2 SFXN4 ENSG00000183605 Sideroflexin 4 10 119140767-119165667 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018028, HPA020872 Approved Supported Vesicles Expressed in all Expressed in all thyroid gland: 47.1 SGF29 CCDC101, FLJ32446, TDRD29 ENSG00000176476 SAGA complex associated factor 29 16 28553915-28591790 Predicted intracellular proteins Evidence at protein level HPA052590, HPA053608 Supported Approved Nucleus
Nucleoli Pancreatic cancer:2.99e-4 (favourable), Lung cancer:3.37e-4 (favourable), Cervical cancer:4.77e-4 (favourable) Expressed in all Expressed in all testis: 41.7 SGK1 SGK ENSG00000118515 Serum/glucocorticoid regulated kinase 1 6 134169246-134318112 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB022085, CAB025148, HPA051251 Approved Supported Nuclear speckles
Cytosol Cervical cancer:5.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 778.6 SGK3 SGK2, SGKL ENSG00000104205 Serum/glucocorticoid regulated kinase family, member 3 8 66712418-66862022 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027146 Supported Breast cancer:5.52e-6 (favourable), Cervical cancer:8.28e-4 (favourable), Pancreatic cancer:9.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 47.7 SGMS1 MGC17342, MOB, SMS1, TMEM23 ENSG00000198964 Sphingomyelin synthase 1 10 50305586-50625163 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045191 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.95e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 114.4 SGPL1 SPL ENSG00000166224 Sphingosine-1-phosphate lyase 1 10 70815961-70881173 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA021125, HPA023086 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all skin: 34.6 SGPP1 ENSG00000126821 Sphingosine-1-phosphate phosphatase 1 14 63684214-63728039 Predicted membrane proteins Evidence at protein level HPA053149, HPA064908 Approved Supported Nucleus Expressed in all Expressed in all placenta: 34.5 SGSH HSS, MPS3A, SFMD ENSG00000181523 N-sulfoglucosamine sulfohydrolase 17 80206716-80220923 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023436, HPA023451 Supported Renal cancer:2.66e-4 (unfavourable), Lung cancer:2.72e-4 (favourable), Pancreatic cancer:3.10e-4 (favourable), Testis cancer:5.37e-4 (unfavourable), Liver cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 36.5 SGSM2 KIAA0397, RUTBC1 ENSG00000141258 Small G protein signaling modulator 2 17 2337498-2381058 Predicted intracellular proteins Evidence at protein level HPA021641, HPA024553 Approved Approved Nucleoplasm
Cytosol Pancreatic cancer:9.00e-6 (favourable), Head and neck cancer:3.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 78.2 SGSM3 DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3 ENSG00000100359 Small G protein signaling modulator 3 22 40370591-40410289 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048980 Approved Supported Golgi apparatus Endometrial cancer:4.47e-5 (favourable) Expressed in all Expressed in all stomach: 76.7 SGTA SGT ENSG00000104969 Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 19 2754714-2783371 Predicted intracellular proteins Evidence at protein level HPA056309 Approved Approved Nucleoplasm Endometrial cancer:1.04e-4 (favourable), Renal cancer:2.35e-4 (favourable), Cervical cancer:9.70e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 64.8 SH2B1 FLJ30542, SH2B ENSG00000178188 SH2B adaptor protein 1 16 28846600-28874212 Predicted intracellular proteins Evidence at protein level HPA076175 Approved Vesicles Renal cancer:2.81e-6 (favourable), Urothelial cancer:1.60e-4 (favourable), Pancreatic cancer:4.38e-4 (favourable), Lung cancer:9.40e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 103.5 SH2B3 IDDM20, LNK ENSG00000111252 SH2B adaptor protein 3 12 111405948-111451623 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA005483 Approved Approved Nucleoplasm Renal cancer:6.20e-4 (unfavourable) Expressed in all Expressed in all spleen: 51.9 SH3BGRL MGC117402 ENSG00000131171 SH3 domain binding glutamate-rich protein like X 81201943-81298547 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA051248 Approved Approved Vesicles Stomach cancer:4.08e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 356.7 SH3BGRL2 ENSG00000198478 SH3 domain binding glutamate-rich protein like 2 6 79631283-79703659 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047486 Approved Supported Nucleoplasm Renal cancer:2.24e-4 (favourable) Expressed in all Expressed in all thyroid gland: 97.9 SH3BGRL3 ENSG00000142669 SH3 domain binding glutamate-rich protein like 3 1 26279176-26281522 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030848, HPA076219 Approved Approved Nuclear bodies Renal cancer:2.17e-10 (unfavourable) Expressed in all Expressed in all epididymis: 444.6 SH3BP2 CRBM, RES4-23 ENSG00000087266 SH3-domain binding protein 2 4 2793023-2841098 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036790 Approved Approved Nucleus
Actin filaments Endometrial cancer:5.42e-6 (unfavourable), Head and neck cancer:1.57e-5 (favourable), Urothelial cancer:2.67e-4 (favourable) Expressed in all Expressed in all spleen: 62.0 SH3BP5 Sab ENSG00000131370 SH3-domain binding protein 5 (BTK-associated) 3 15254853-15341368 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036445, HPA057988 Uncertain Supported Nucleoplasm
Nuclear bodies Renal cancer:8.17e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 222.2 SH3BP5L KIAA1720 ENSG00000175137 SH3-binding domain protein 5-like 1 248810446-248826633 Predicted intracellular proteins Evidence at protein level HPA038067, HPA038068 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Expressed in all cerebral cortex: 19.8 SH3GL1 CNSA1, EEN, MGC111371, SH3D2B, SH3P8 ENSG00000141985 SH3-domain GRB2-like 1 19 4360370-4400547 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021485 Approved Validated Cytosol Renal cancer:9.36e-8 (unfavourable), Liver cancer:1.10e-4 (unfavourable), Cervical cancer:1.50e-4 (favourable), Endometrial cancer:1.86e-4 (favourable) Expressed in all Expressed in all esophagus: 115.0 SH3GLB1 Bif-1, CGI-61, KIAA0491, PPP1R70 ENSG00000097033 SH3-domain GRB2-like endophilin B1 1 86704570-86748184 Predicted intracellular proteins Evidence at protein level CAB004650, HPA015608, HPA019900 Supported Supported Cytosol Liver cancer:2.90e-5 (unfavourable), Pancreatic cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all testis: 197.5 SH3GLB2 KIAA1848 ENSG00000148341 SH3-domain GRB2-like endophilin B2 9 129007036-129028303 Predicted intracellular proteins Evidence at protein level HPA021438, HPA024734 Approved Supported Nucleoplasm
Cytosol Cervical cancer:1.56e-6 (favourable), Renal cancer:2.32e-4 (favourable), Urothelial cancer:4.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 92.4 SH3KBP1 CIN85 ENSG00000147010 SH3-domain kinase binding protein 1 X 19533975-19887601 Predicted intracellular proteins Evidence at protein level HPA003351, HPA003355, CAB021892 Supported Supported Cytosol Renal cancer:2.10e-6 (unfavourable) Expressed in all Expressed in all lymph node: 80.5 SH3RF1 KIAA1494, POSH, RNF142, SH3MD2 ENSG00000154447 SH3 domain containing ring finger 1 4 169094256-169271105 Predicted intracellular proteins Evidence at protein level HPA074783 Uncertain Vesicles
Intermediate filaments Renal cancer:5.51e-8 (favourable) Expressed in all Expressed in all thyroid gland: 32.0 SH3YL1 DKFZP586F1318, Ray ENSG00000035115 SH3 and SYLF domain containing 1 2 217730-266398 Predicted intracellular proteins Evidence at protein level HPA030926, HPA030927 Approved Approved Nucleus Renal cancer:7.70e-4 (favourable) Expressed in all Expressed in all kidney: 149.0 SHARPIN DKFZP434N1923, SIPL1 ENSG00000179526 SHANK-associated RH domain interactor 8 144098633-144108124 Predicted intracellular proteins Evidence at protein level HPA044453 Approved Supported Nucleus
Cytosol Expressed in all Expressed in all testis: 66.1 SHB ENSG00000107338 Src homology 2 domain containing adaptor protein B 9 37919134-38069211 Predicted intracellular proteins Evidence at protein level CAB010161, HPA049911, HPA052108 Uncertain Validated Nucleoplasm
Cytosol
Cytoplasmic bodies Expressed in all Expressed in all parathyroid gland: 15.9 SHC1 p66, SHC, ShcA ENSG00000160691 SHC (Src homology 2 domain containing) transforming protein 1 1 154962298-154974395 Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA001844, CAB005374, CAB016305 Supported Validated Cytosol Renal cancer:2.22e-16 (unfavourable), Lung cancer:1.92e-4 (unfavourable), Cervical cancer:6.74e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 161.1 SHFM1 DSS1, ECD, SEM1, SHFD1, Shfdg1, SHSF1 ENSG00000127922 Split hand/foot malformation (ectrodactyly) type 1 7 96481626-96709891 Predicted intracellular proteins Evidence at protein level HPA020429, HPA072648 Uncertain Approved Cytosol Urothelial cancer:8.00e-5 (favourable), Ovarian cancer:2.52e-4 (favourable), Renal cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all testis: 222.1 SHISA5 hShisa5, SCOTIN ENSG00000164054 Shisa family member 5 3 48467798-48504826 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042295 Approved Liver cancer:3.72e-6 (unfavourable), Renal cancer:8.64e-5 (unfavourable) Expressed in all Expressed in all placenta: 197.8 SHKBP1 PP203, Sb1 ENSG00000160410 SH3KBP1 binding protein 1 19 40576851-40591399 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA041887 Uncertain Approved Cell Junctions Expressed in all Expressed in all spleen: 54.3 SHMT1 CSHMT, MGC15229, MGC24556, SHMT ENSG00000176974 Serine hydroxymethyltransferase 1 (soluble) 17 18327860-18363563 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA023314 Approved Supported Nucleus
Cytosol Renal cancer:8.54e-6 (favourable), Liver cancer:2.52e-4 (favourable) Expressed in all Expressed in all kidney: 270.2 SHMT2 SHMT ENSG00000182199 Serine hydroxymethyltransferase 2 (mitochondrial) 12 57229327-57234935 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020543, HPA020549 Supported Validated Microtubules
Mitochondria Renal cancer:4.84e-8 (unfavourable), Breast cancer:8.37e-5 (unfavourable) Expressed in all Expressed in all liver: 74.8 SHOC2 KIAA0862, SOC-2, SOC2, SUR-8, SUR8 ENSG00000108061 SHOC2 leucine-rich repeat scaffold protein 10 110919547-111013667 Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA009164 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 65.0 SHQ1 FLJ10539, Shq1p ENSG00000144736 SHQ1, H/ACA ribonucleoprotein assembly factor 3 72749277-72861914 Predicted intracellular proteins Evidence at protein level HPA042792 Uncertain Supported Nucleoplasm Colorectal cancer:2.83e-4 (favourable), Endometrial cancer:6.49e-4 (favourable) Expressed in all Expressed in all testis: 18.0 SIAE CSE-C, LSE, MGC87009, YSG2 ENSG00000110013 Sialic acid acetylesterase 11 124633113-124695707 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038052, HPA038053 Approved Renal cancer:4.42e-11 (favourable), Endometrial cancer:4.66e-5 (favourable) Expressed in all Expressed in all rectum: 116.8 SIAH1 hSIAH1 ENSG00000196470 Siah E3 ubiquitin protein ligase 1 16 48356364-48448402 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018724 Supported Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all placenta: 70.8 SIAH2 ENSG00000181788 Siah E3 ubiquitin protein ligase 2 3 150741127-150763477 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA061293, CAB069930 Approved Supported Nucleoplasm
Vesicles Pancreatic cancer:8.21e-5 (unfavourable), Breast cancer:1.17e-4 (favourable) Expressed in all Expressed in all adrenal gland: 95.8 SIDT2 CGI-40 ENSG00000149577 SID1 transmembrane family, member 2 11 117178733-117197445 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA052352 Approved Renal cancer:4.18e-5 (unfavourable) Expressed in all Expressed in all prostate: 59.7 SIGIRR TIR8 ENSG00000185187 Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 11 405716-417455 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023188 Approved Approved Nucleoli fibrillar center
Cytosol Renal cancer:7.61e-6 (favourable), Endometrial cancer:1.34e-5 (favourable), Urothelial cancer:1.54e-5 (favourable), Cervical cancer:7.44e-5 (favourable), Head and neck cancer:9.08e-4 (favourable) Expressed in all Expressed in all spleen: 65.9 SIGMAR1 OPRS1, SR-BP1 ENSG00000147955 Sigma non-opioid intracellular receptor 1 9 34634722-34637809 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level CAB013470, HPA018002, HPA024071 Approved Urothelial cancer:3.42e-4 (unfavourable) Expressed in all Expressed in all liver: 67.8 SIK2 DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2 ENSG00000170145 Salt-inducible kinase 2 11 111602391-111730853 Enzymes, Predicted membrane proteins Evidence at protein level HPA016026 Approved Approved Golgi apparatus Renal cancer:1.17e-9 (favourable), Liver cancer:4.93e-4 (favourable) Expressed in all Expressed in all adipose tissue: 32.3 SIK3 FLJ12240, KIAA0999, L19, QSK ENSG00000160584 SIK family kinase 3 11 116843402-117098437 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045245, HPA048161 Approved Approved Nucleoplasm Renal cancer:1.12e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 43.0 SIKE1 FLJ21168, SIKE ENSG00000052723 Suppressor of IKBKE 1 1 114769479-114780685 Predicted intracellular proteins Evidence at protein level HPA024177, HPA025726 Supported Approved Vesicles
Focal adhesion sites Expressed in all Expressed in all thyroid gland: 19.3 SIL1 BAP, MSS, ULG5 ENSG00000120725 SIL1 nucleotide exchange factor 5 138946720-139293557 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA011949 Supported Glioma:3.77e-4 (unfavourable), Endometrial cancer:4.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 59.8 SIN3A DKFZP434K2235, KIAA0700 ENSG00000169375 SIN3 transcription regulator family member A 15 75369379-75455842 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004506, HPA047213, HPA062123 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 55.4 SIN3B KIAA0700 ENSG00000127511 SIN3 transcription regulator family member B 19 16829400-16880353 Predicted intracellular proteins Evidence at protein level HPA050329 Uncertain Approved Nucleoplasm
Plasma membrane Prostate cancer:3.58e-4 (unfavourable), Pancreatic cancer:4.37e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 110.4 SIPA1L1 E6TP1, KIAA0440 ENSG00000197555 Signal-induced proliferation-associated 1 like 1 14 71320449-71741229 Predicted intracellular proteins Evidence at protein level HPA002875 Approved Approved Plasma membrane
Actin filaments Renal cancer:6.80e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 46.2 SIRPA BIT, CD172a, MFR, MYD-1, P84, PTPNS1, SHPS-1, SHPS1, SIRP, SIRP-ALPHA-1, SIRPalpha, SIRPalpha2 ENSG00000198053 Signal-regulatory protein alpha 20 1894167-1940592 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB002776, CAB015122, HPA054437, HPA058511 Approved Expressed in all Expressed in all cerebral cortex: 208.5 SIRT1 SIR2L1 ENSG00000096717 Sirtuin 1 10 67884669-67918390 Predicted intracellular proteins Evidence at protein level CAB003855, HPA006295, HPA052351 Approved Validated Nucleus
Mitochondria
Cytosol Expressed in all Expressed in all testis: 48.8 SIRT2 SIR2L ENSG00000068903 Sirtuin 2 19 38878555-38899862 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB004573, HPA011165 Approved Approved Nucleus
Nucleoli
Cytosol Endometrial cancer:7.20e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 84.2 SIRT3 SIR2L3 ENSG00000142082 Sirtuin 3 11 215458-236931 Predicted intracellular proteins Evidence at protein level HPA026809, CAB037142 Approved Renal cancer:4.85e-9 (favourable), Endometrial cancer:8.51e-5 (favourable), Pancreatic cancer:4.45e-4 (favourable), Glioma:9.21e-4 (unfavourable) Expressed in all Expressed in all epididymis: 49.8 SIRT5 ENSG00000124523 Sirtuin 5 6 13574529-13615158 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA021798, HPA022002, HPA022992 Approved Validated Mitochondria Renal cancer:8.76e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 20.2 SIRT6 ENSG00000077463 Sirtuin 6 19 4174109-4182604 Predicted intracellular proteins Evidence at protein level HPA049729, HPA071776 Supported Supported Nucleoplasm Urothelial cancer:2.58e-4 (favourable), Endometrial cancer:2.85e-4 (favourable), Stomach cancer:9.13e-4 (favourable) Expressed in all Expressed in all colon: 13.5 SIVA1 CD27BP, SIVA, Siva-1, Siva-2 ENSG00000184990 SIVA1, apoptosis-inducing factor 14 104753100-104768494 Predicted intracellular proteins Evidence at protein level HPA065398, HPA066693 Supported Nucleoplasm Cervical cancer:5.95e-4 (favourable) Expressed in all Expressed in all bone marrow: 62.2 SKA2 FAM33A, FLJ12758 ENSG00000182628 Spindle and kinetochore associated complex subunit 2 17 59109951-59155269 Predicted intracellular proteins Evidence at protein level HPA059235 Uncertain Renal cancer:2.90e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.1 SKAP2 RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R ENSG00000005020 Src kinase associated phosphoprotein 2 7 26667062-26995239 Predicted intracellular proteins Evidence at protein level HPA005560, HPA024045 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 53.7 SKI ENSG00000157933 SKI proto-oncogene 1 2228695-2310119 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010449, HPA066567 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all endometrium: 36.1 SKIL SNO, SnoA, SnoN ENSG00000136603 SKI-like proto-oncogene 3 170357678-170396835 Predicted intracellular proteins Evidence at protein level HPA008472 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.19e-7 (unfavourable) Expressed in all Expressed in all gallbladder: 37.0 SKIV2L2 Dob1, fSAP118, KIAA0052, Mtr4 ENSG00000039123 Superkiller viralicidic activity 2-like 2 (S. cerevisiae) 5 55307760-55425581 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037379 Supported Supported Nucleus Expressed in all Expressed in all parathyroid gland: 42.3 SKP1 EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L ENSG00000113558 S-phase kinase-associated protein 1 5 134148935-134177038 Predicted intracellular proteins Evidence at protein level CAB012982, HPA053745, HPA058134 Approved Supported Nucleus
Cytosol Renal cancer:5.20e-4 (favourable), Liver cancer:5.72e-4 (unfavourable), Breast cancer:7.53e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 932.4 SLAIN1 C13orf32, FLJ30046 ENSG00000139737 SLAIN motif family, member 1 13 77697854-77764242 Predicted intracellular proteins Evidence at protein level HPA040798 Approved Nucleoplasm
Intermediate filaments
Cytosol Ovarian cancer:9.07e-4 (favourable) Tissue enhanced Expressed in all cerebral cortex: 217.7 SLAIN2 FLJ21611, KIAA1458 ENSG00000109171 SLAIN motif family, member 2 4 48341322-48426212 Predicted intracellular proteins Evidence at protein level HPA035824, HPA063599 Approved Validated Centrosome
Cytosol Renal cancer:1.50e-4 (favourable), Colorectal cancer:5.77e-4 (favourable), Pancreatic cancer:6.71e-4 (unfavourable), Endometrial cancer:7.98e-4 (favourable) Expressed in all Expressed in all testis: 72.6 SLBP HBP ENSG00000163950 Stem-loop binding protein 4 1692800-1712555 Predicted intracellular proteins Evidence at protein level HPA019254, HPA061670 Supported Supported Nucleus
Nucleoli
Cytosol Liver cancer:2.29e-5 (unfavourable) Expressed in all Expressed in all testis: 130.2 SLC10A3 DXS253E, P3 ENSG00000126903 Solute carrier family 10, member 3 X 154487306-154490690 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA021656 Approved Approved Intermediate filaments Colorectal cancer:4.15e-5 (unfavourable), Cervical cancer:4.53e-4 (favourable), Pancreatic cancer:7.22e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 33.2 SLC11A2 DCT1, DMT1, NRAMP2 ENSG00000110911 Solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 12 50979401-51028566 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA032139, HPA032140 Uncertain Supported Mitochondria Lung cancer:3.07e-6 (favourable) Expressed in all Expressed in all thyroid gland: 74.8 SLC12A2 BSC, BSC2, NKCC1, PPP1R141 ENSG00000064651 Solute carrier family 12 (sodium/potassium/chloride transporter), member 2 5 128083766-128189688 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA020130, HPA063697 Approved Approved Vesicles
Plasma membrane Renal cancer:7.09e-4 (favourable), Endometrial cancer:8.60e-4 (favourable) Expressed in all Expressed in all rectum: 66.4 SLC12A4 KCC1 ENSG00000124067 Solute carrier family 12 (potassium/chloride transporter), member 4 16 67943474-67969601 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA041138 Approved Approved Endosomes Renal cancer:2.25e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 62.5 SLC15A3 hPTR3, PHT2 ENSG00000110446 Solute carrier family 15 (oligopeptide transporter), member 3 11 60937083-60952530 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA047880, HPA057642 Approved Supported Vesicles Cervical cancer:4.07e-5 (favourable) Expressed in all Expressed in all lung: 102.3 SLC15A4 PHT1, PTR4 ENSG00000139370 Solute carrier family 15 (oligopeptide transporter), member 4 12 128793191-128823983 Predicted membrane proteins, Transporters Evidence at protein level HPA016713 Approved Renal cancer:7.56e-6 (unfavourable), Liver cancer:6.78e-4 (unfavourable), Head and neck cancer:8.45e-4 (unfavourable) Expressed in all Expressed in all lymph node: 27.7 SLC16A3 MCT3, MCT4 ENSG00000141526 Solute carrier family 16 (monocarboxylate transporter), member 3 17 82228397-82261129 Predicted membrane proteins, Transporters Evidence at protein level CAB017490, HPA021451 Approved Supported Nuclear membrane
Plasma membrane Liver cancer:1.19e-7 (unfavourable), Renal cancer:3.71e-7 (unfavourable), Lung cancer:2.02e-5 (unfavourable), Cervical cancer:6.07e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 74.4 SLC18B1 C6orf192, dJ55C23.6 ENSG00000146409 Solute carrier family 18, subfamily B, member 1 6 132769370-132798553 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029747, HPA049659 Approved Supported Golgi apparatus
Cytosol Head and neck cancer:3.55e-4 (favourable), Liver cancer:7.90e-4 (unfavourable), Renal cancer:9.24e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 37.6 SLC19A2 THTR1, TRMA ENSG00000117479 Solute carrier family 19 (thiamine transporter), member 2 1 169463909-169486003 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA006119, HPA016599 Uncertain Approved Cytosol Renal cancer:2.70e-5 (favourable), Glioma:2.11e-4 (favourable), Breast cancer:8.41e-4 (favourable) Expressed in all Expressed in all gallbladder: 49.3 SLC1A4 ASCT1, SATT ENSG00000115902 Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2 64988477-65023865 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA034963, HPA034964 Approved Validated Microtubule organizing center
Centrosome Liver cancer:4.23e-5 (unfavourable), Cervical cancer:3.59e-4 (favourable), Renal cancer:4.87e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 79.3 SLC1A5 AAAT, ASCT2, M7V1, RDRC ENSG00000105281 Solute carrier family 1 (neutral amino acid transporter), member 5 19 46774883-46788594 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035239, HPA035240 Supported Validated Plasma membrane Liver cancer:1.66e-8 (unfavourable), Renal cancer:1.18e-7 (unfavourable) Expressed in all Expressed in all epididymis: 117.4 SLC20A1 Glvr-1, GLVR1, PiT-1 ENSG00000144136 Solute carrier family 20 (phosphate transporter), member 1 2 112645857-112663827 Predicted membrane proteins, Transporters Evidence at protein level CAB019279, HPA035834 Approved Approved Vesicles Renal cancer:3.44e-5 (unfavourable), Head and neck cancer:6.56e-5 (unfavourable) Expressed in all Expressed in all colon: 51.9 SLC20A2 Glvr-2, GLVR2, MLVAR, PiT-2 ENSG00000168575 Solute carrier family 20 (phosphate transporter), member 2 8 42416475-42541926 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA026540 Approved Renal cancer:1.01e-4 (favourable), Breast cancer:7.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 137.7 SLC22A23 C6orf85, FLJ22174 ENSG00000137266 Solute carrier family 22, member 23 6 3268962-3457022 Predicted membrane proteins, Transporters Evidence at protein level HPA014697 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:2.39e-4 (unfavourable), Endometrial cancer:6.57e-4 (favourable) Expressed in all Expressed in all stomach: 28.2 SLC23A2 KIAA0238, SLC23A1, SVCT2, YSPL2 ENSG00000089057 Solute carrier family 23 (ascorbic acid transporter), member 2 20 4852356-5010293 Predicted membrane proteins, Transporters Evidence at protein level HPA052825, HPA059314 Approved Supported Golgi apparatus
Vesicles Urothelial cancer:6.08e-5 (favourable), Pancreatic cancer:7.14e-5 (favourable), Liver cancer:3.35e-4 (favourable) Expressed in all Expressed in all adrenal gland: 98.6 SLC25A1 CTP, SLC20A3 ENSG00000100075 Solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 22 19175575-19178830 Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level Expressed in all Expressed in all duodenum: 115.9 SLC25A11 OGC, SLC20A4 ENSG00000108528 Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 17 4937130-4940251 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA021167 Approved Renal cancer:2.84e-9 (favourable), Pancreatic cancer:6.41e-6 (favourable) Expressed in all Expressed in all heart muscle: 148.2 SLC25A13 ARALAR2, CITRIN, CTLN2 ENSG00000004864 Solute carrier family 25 (aspartate/glutamate carrier), member 13 7 96120220-96322147 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA018997 Approved Supported Mitochondria Renal cancer:9.14e-4 (favourable) Expressed in all Expressed in all liver: 77.3 SLC25A15 D13S327, HHH, ORC1, ORNT1 ENSG00000102743 Solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 13 40789412-40810111 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA042146 Approved Renal cancer:1.74e-4 (favourable), Liver cancer:2.16e-4 (favourable), Urothelial cancer:5.46e-4 (unfavourable) Expressed in all Expressed in all liver: 49.6 SLC25A17 PMP34 ENSG00000100372 Solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 22 40769630-40819399 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA052708, HPA060972 Approved Supported Peroxisomes Expressed in all Expressed in all ovary: 24.0 SLC25A19 DNC, MCPHA, MUP1, TPC ENSG00000125454 Solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 17 75272981-75289510 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level Liver cancer:1.21e-7 (unfavourable), Endometrial cancer:8.72e-5 (unfavourable) Expressed in all Expressed in all testis: 49.5 SLC25A20 CAC, CACT ENSG00000178537 Solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 3 48856931-48898993 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016862, HPA029863 Approved Supported Mitochondria
Cytosol Expressed in all Expressed in all liver: 70.8 SLC25A24 APC1, DKFZp586G0123 ENSG00000085491 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1 108134036-108200849 Predicted intracellular proteins, Transporters Evidence at protein level HPA028519, HPA063636 Supported Validated Mitochondria Colorectal cancer:1.01e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 44.3 SLC25A25 KIAA1896, MCSC, PCSCL ENSG00000148339 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 9 128068201-128109245 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA020381 Uncertain Supported Vesicles
Mitochondria Renal cancer:4.65e-6 (favourable), Liver cancer:1.01e-4 (favourable) Expressed in all Expressed in all gallbladder: 63.1 SLC25A26 ENSG00000144741 Solute carrier family 25 (S-adenosylmethionine carrier), member 26 3 66133610-66388116 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA026887 Supported Supported Mitochondria Renal cancer:1.73e-5 (favourable) Expressed in all Expressed in all thyroid gland: 17.4 SLC25A28 MRS3/4, MRS4L ENSG00000155287 Solute carrier family 25 (mitochondrial iron transporter), member 28 10 99610522-99620609 Predicted intracellular proteins, Transporters Evidence at protein level Cervical cancer:2.18e-6 (favourable), Renal cancer:7.28e-5 (unfavourable) Expressed in all Expressed in all testis: 93.2 SLC25A29 C14orf69, FLJ38975 ENSG00000197119 Solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 14 100291111-100306547 Predicted intracellular proteins, Transporters Evidence at protein level HPA030781 Uncertain Pancreatic cancer:2.90e-4 (favourable), Urothelial cancer:5.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 158.5 SLC25A3 PHC ENSG00000075415 Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 12 98593591-98606379 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA045709 Supported Mitochondria Renal cancer:8.11e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 583.9 SLC25A30 ENSG00000174032 Solute carrier family 25, member 30 13 45393316-45418455 Predicted intracellular proteins, Transporters Evidence at protein level HPA045260 Approved Nucleoplasm Renal cancer:9.91e-8 (favourable), Ovarian cancer:3.32e-4 (unfavourable) Expressed in all Expressed in all kidney: 43.2 SLC25A32 MFTC ENSG00000164933 Solute carrier family 25 (mitochondrial folate carrier), member 32 8 103398635-103415189 Predicted intracellular proteins, Transporters Evidence at protein level HPA024763, HPA047402 Uncertain Supported Mitochondria Renal cancer:1.53e-6 (unfavourable), Lung cancer:2.09e-4 (unfavourable), Endometrial cancer:7.23e-4 (unfavourable) Expressed in all Expressed in all lymph node: 21.3 SLC25A36 FLJ10618, PNC2 ENSG00000114120 Solute carrier family 25 (pyrimidine nucleotide carrier), member 36 3 140941830-140979933 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA027036 Approved Approved Nucleus
Mitochondria
Cytosol Urothelial cancer:1.55e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 68.3 SLC25A37 MFRN, MFRN1, MSCP ENSG00000147454 Solute carrier family 25 (mitochondrial iron transporter), member 37 8 23528805-23575463 Predicted intracellular proteins, Transporters Evidence at protein level HPA045680 Uncertain Renal cancer:4.37e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 80.2 SLC25A38 FLJ20551 ENSG00000144659 Solute carrier family 25, member 38 3 39383348-39397351 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA041027 Approved Renal cancer:1.58e-5 (favourable), Urothelial cancer:7.29e-4 (favourable) Expressed in all Expressed in all thyroid gland: 65.8 SLC25A39 CGI-69, FLJ22407 ENSG00000013306 Solute carrier family 25, member 39 17 44319625-44324870 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level HPA026785 Approved Renal cancer:3.58e-5 (favourable), Liver cancer:5.90e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 181.5 SLC25A42 MGC26694 ENSG00000181035 Solute carrier family 25, member 42 19 19063999-19112888 Predicted membrane proteins, Transporters Evidence at protein level HPA049449 Approved Supported Mitochondria Lung cancer:4.11e-4 (favourable), Cervical cancer:5.04e-4 (favourable) Expressed in all Expressed in all kidney: 28.7 SLC25A44 FLJ90431, KIAA0446 ENSG00000160785 Solute carrier family 25, member 44 1 156193932-156212796 Predicted membrane proteins, Transporters Evidence at protein level HPA065411 Approved Nucleus
Mitochondria Pancreatic cancer:2.49e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 43.1 SLC25A45 ENSG00000162241 Solute carrier family 25, member 45 11 65375192-65383701 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA050821 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:2.83e-4 (favourable) Expressed in all Expressed in all spleen: 12.6 SLC25A46 ENSG00000164209 Solute carrier family 25, member 46 5 110738136-110765161 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039601, HPA071582 Approved Supported Mitochondria Thyroid cancer:2.52e-4 (unfavourable), Colorectal cancer:8.41e-4 (favourable) Expressed in all Expressed in all testis: 37.3 SLC25A5 2F1, ANT2, T2, T3 ENSG00000005022 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 X 119468400-119471319 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA046835, HPA071684 Approved Supported Mitochondria Renal cancer:8.06e-6 (favourable), Cervical cancer:7.35e-4 (favourable), Colorectal cancer:7.47e-4 (favourable) Expressed in all Expressed in all duodenum: 791.0 SLC25A51 CG7943, MCART1, MGC14836 ENSG00000122696 Solute carrier family 25, member 51 9 37879400-37904353 Predicted membrane proteins, Transporters Evidence at protein level HPA046388, HPA058261 Uncertain Approved Mitochondria Liver cancer:5.67e-5 (unfavourable), Renal cancer:1.52e-4 (favourable), Thyroid cancer:2.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 16.4 SLC25A6 ANT3, ANT3Y, MGC17525 ENSG00000169100 Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 X 1386152-1392724 FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA046835, HPA071684 Approved Supported Mitochondria Expressed in all Expressed in all duodenum: 294.5 SLC26A11 ENSG00000181045 Solute carrier family 26 (anion exchanger), member 11 17 80219699-80253500 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA029893 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Liver cancer:1.82e-6 (unfavourable), Pancreatic cancer:1.43e-5 (favourable), Endometrial cancer:1.55e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 34.5 SLC26A6 DKFZp586E1422 ENSG00000225697 Solute carrier family 26 (anion exchanger), member 6 3 48625723-48635493 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA048363 Approved Uncertain Cytosol Renal cancer:1.53e-5 (unfavourable), Liver cancer:3.92e-4 (unfavourable) Expressed in all Expressed in all rectum: 24.3 SLC27A4 ACSVL4, FATP4 ENSG00000167114 Solute carrier family 27 (fatty acid transporter), member 4 9 128340646-128361470 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA007293, CAB009771 Approved Supported Vesicles Renal cancer:2.61e-5 (favourable) Expressed in all Expressed in all duodenum: 74.1 SLC29A1 ENT1 ENSG00000112759 Solute carrier family 29 (equilibrative nucleoside transporter), member 1 6 44219505-44234151 Predicted membrane proteins, Transporters Evidence at protein level HPA012384 Approved Renal cancer:2.96e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 125.1 SLC2A4RG GEF, HDBP1, Si-1-2, Si-1-2-19 ENSG00000125520 SLC2A4 regulator 20 63739861-63743505 Predicted intracellular proteins, Transporters Evidence at protein level HPA063050 Supported Nuclear speckles Expressed in all Expressed in all adipose tissue: 53.6 SLC2A8 GLUT8, GLUTX1 ENSG00000136856 Solute carrier family 2 (facilitated glucose transporter), member 8 9 127397138-127408424 Predicted membrane proteins, Transporters Evidence at protein level HPA011935 Uncertain Approved Vesicles Cervical cancer:2.57e-6 (favourable), Renal cancer:6.55e-6 (favourable), Pancreatic cancer:9.86e-6 (favourable) Expressed in all Expressed in all testis: 50.1 SLC30A5 FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1 ENSG00000145740 Solute carrier family 30 (zinc transporter), member 5 5 69093646-69131069 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA035373 Approved Supported Nucleus
Golgi apparatus Expressed in all Expressed in all thyroid gland: 61.6 SLC30A6 FLJ31101, ZNT6 ENSG00000152683 Solute carrier family 30 (zinc transporter), member 6 2 32165841-32224379 Predicted membrane proteins, Transporters Evidence at protein level HPA055032, HPA057328 Uncertain Validated Golgi apparatus Liver cancer:9.58e-6 (unfavourable), Endometrial cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.7 SLC30A9 C4orf1, GAC63, HUEL, ZNT9 ENSG00000014824 Solute carrier family 30 (zinc transporter), member 9 4 41990472-42090457 Predicted membrane proteins, Transporters Evidence at protein level HPA004014 Approved Renal cancer:2.86e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 35.7 SLC31A1 COPT1, CTR1, hCTR1 ENSG00000136868 Solute carrier family 31 (copper transporter), member 1 9 113221562-113264492 Predicted membrane proteins, Transporters Evidence at protein level HPA013810 Approved Renal cancer:2.20e-6 (favourable), Thyroid cancer:2.03e-4 (unfavourable) Expressed in all Expressed in all liver: 56.5 SLC31A2 COPT2, CTR2, hCTR2 ENSG00000136867 Solute carrier family 31 (copper transporter), member 2 9 113150942-113164137 Predicted membrane proteins, Transporters Evidence at protein level HPA014861 Approved Approved Nuclear speckles
Plasma membrane
Intermediate filaments Mixed Expressed in all salivary gland: 170.9 SLC33A1 ACATN, AT-1, AT1, SPG42 ENSG00000169359 Solute carrier family 33 (acetyl-CoA transporter), member 1 3 155821024-155854429 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA042430 Uncertain Expressed in all Expressed in all thyroid gland: 67.1 SLC35A1 CMPST, hCST ENSG00000164414 Solute carrier family 35 (CMP-sialic acid transporter), member A1 6 87470623-87512336 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Renal cancer:2.70e-6 (unfavourable) Expressed in all Expressed in all prostate: 59.9 SLC35A2 UGALT, UGAT, UGT, UGT1, UGT2, UGTL ENSG00000102100 Solute carrier family 35 (UDP-galactose transporter), member A2 X 48903180-48911958 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036087 Approved Supported Golgi apparatus Liver cancer:9.64e-5 (unfavourable), Breast cancer:3.16e-4 (unfavourable), Stomach cancer:8.23e-4 (favourable) Expressed in all Expressed in all fallopian tube: 44.1 SLC35A3 ENSG00000117620 Solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1 99969789-100026979 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA015253 Uncertain Expressed in all Expressed in all rectum: 47.2 SLC35A4 ENSG00000176087 Solute carrier family 35, member A4 5 140564456-140569103 Predicted membrane proteins, Transporters Evidence at protein level HPA062210 Approved Nucleoplasm Renal cancer:4.56e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 110.8 SLC35A5 FLJ20730 ENSG00000138459 Solute carrier family 35, member A5 3 112561709-112585577 Predicted membrane proteins, Transporters Evidence at protein level HPA035519, HPA057964 Uncertain Approved Golgi apparatus Renal cancer:4.10e-5 (favourable) Expressed in all Expressed in all thyroid gland: 43.7 SLC35B1 UGTREL1 ENSG00000121073 Solute carrier family 35, member B1 17 49700943-49709014 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA048655, HPA057418 Approved Approved Nucleus
Endoplasmic reticulum
Vesicles Renal cancer:5.69e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 52.0 SLC35B2 UGTrel4 ENSG00000157593 Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 6 44254096-44257890 Predicted membrane proteins, Transporters Evidence at protein level HPA029638 Approved Approved Vesicles Liver cancer:8.59e-5 (unfavourable), Prostate cancer:6.07e-4 (favourable), Breast cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.0 SLC35B3 C6orf196, CGI-19, dJ453H5.1, PAPST2 ENSG00000124786 Solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 6 8413068-8435483 Predicted membrane proteins, Transporters Evidence at protein level HPA054661, HPA057801 Approved Expressed in all Expressed in all epididymis: 62.2 SLC35C1 FLJ11320, FUCT1 ENSG00000181830 Solute carrier family 35 (GDP-fucose transporter), member C1 11 45804072-45813015 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA064001 Supported Supported Golgi apparatus Thyroid cancer:3.64e-4 (favourable) Expressed in all Expressed in all esophagus: 29.5 SLC35C2 bA394O2.1, C20orf5, CGI-15, OVCOV1 ENSG00000080189 Solute carrier family 35 (GDP-fucose transporter), member C2 20 46345980-46364458 Predicted membrane proteins, Transporters Evidence at protein level HPA027011 Approved Supported Nucleoplasm
Golgi apparatus Liver cancer:1.08e-4 (unfavourable), Renal cancer:8.68e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 36.6 SLC35D1 KIAA0260, UGTREL7 ENSG00000116704 Solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1 66999332-67054099 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level Lung cancer:6.55e-4 (unfavourable), Endometrial cancer:7.47e-4 (unfavourable) Expressed in all Expressed in all liver: 38.5 SLC35D2 SQV7L, UGTrel8 ENSG00000130958 Solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 9 96320706-96383710 Predicted membrane proteins, Transporters Evidence at protein level HPA064047 Approved Validated Golgi apparatus Expressed in all Expressed in all small intestine: 73.8 SLC35E1 FLJ14251 ENSG00000127526 Solute carrier family 35, member E1 19 16549831-16572382 Predicted membrane proteins, Transporters Evidence at protein level HPA016570, HPA062214 Approved Validated Golgi apparatus Expressed in all Expressed in all parathyroid gland: 29.2 SLC35E2B ENSG00000189339 Solute carrier family 35, member E2B 1 1659529-1692728 Predicted membrane proteins, Transporters Evidence at protein level HPA045641, HPA062711 Uncertain Uncertain Nucleus Urothelial cancer:5.15e-4 (favourable), Head and neck cancer:7.64e-4 (favourable) Expressed in all Expressed in all smooth muscle: 47.0 SLC35F5 FLJ22004 ENSG00000115084 Solute carrier family 35, member F5 2 113705011-113756823 Predicted membrane proteins, Transporters Evidence at transcript level HPA034828, HPA049229 Uncertain Uncertain Plasma membrane Renal cancer:1.71e-5 (favourable), Cervical cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 65.7 SLC35F6 ANT2BP, C2orf18, FLJ20555, TANGO9 ENSG00000213699 Solute carrier family 35, member F6 2 26764284-26781231 Predicted membrane proteins, Transporters Evidence at protein level HPA034655 Approved Approved Nucleoplasm
Vesicles
Cytosol Liver cancer:1.11e-4 (unfavourable), Lung cancer:3.71e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 26.2 SLC37A3 DKFZp761N0624 ENSG00000157800 Solute carrier family 37, member 3 7 140293693-140404433 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014713, HPA061841 Supported Cytosol Liver cancer:4.78e-5 (unfavourable), Cervical cancer:9.54e-4 (unfavourable) Expressed in all Expressed in all endometrium: 72.5 SLC38A1 ATA1, NAT2, SAT1 ENSG00000111371 Solute carrier family 38, member 1 12 46183063-46270017 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA039460, HPA052272 Uncertain Supported Liver cancer:6.95e-8 (unfavourable), Endometrial cancer:4.76e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 153.2 SLC38A10 MGC15523, PP1744 ENSG00000157637 Solute carrier family 38, member 10 17 81245000-81295547 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA021374, HPA023161, HPA024631 Supported Validated Golgi apparatus Renal cancer:5.34e-7 (unfavourable), Pancreatic cancer:2.92e-4 (favourable) Expressed in all Expressed in all thyroid gland: 44.6 SLC38A2 ATA2, KIAA1382, SAT2, SNAT2 ENSG00000134294 Solute carrier family 38, member 2 12 46358189-46372867 Predicted membrane proteins Evidence at protein level HPA035180 Approved Approved Vesicles Expressed in all Expressed in all skin: 239.3 SLC38A9 FLJ90709 ENSG00000177058 Solute carrier family 38, member 9 5 55625845-55773194 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043785 Uncertain Approved Nucleoplasm
Vesicles Endometrial cancer:7.24e-5 (unfavourable) Expressed in all Expressed in all placenta: 79.8 SLC39A1 ZIP1, ZIRTL ENSG00000143570 Solute carrier family 39 (zinc transporter), member 1 1 153959099-153968184 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016506 Uncertain Cytosol Liver cancer:4.12e-7 (unfavourable), Head and neck cancer:5.26e-5 (unfavourable), Cervical cancer:4.83e-4 (unfavourable) Expressed in all Expressed in all placenta: 133.4 SLC39A11 C17orf26 ENSG00000133195 Solute carrier family 39, member 11 17 72645949-73092712 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA021455 Approved Nucleoplasm Expressed in all Expressed in all thyroid gland: 60.0 SLC39A13 FLJ25785 ENSG00000165915 Solute carrier family 39 (zinc transporter), member 13 11 47407132-47416501 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA043971 Approved Uncertain Cytosol Ovarian cancer:2.73e-5 (unfavourable), Renal cancer:1.96e-4 (favourable), Colorectal cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all placenta: 58.0 SLC39A3 ZIP3 ENSG00000141873 Solute carrier family 39 (zinc transporter), member 3 19 2732204-2740152 Predicted membrane proteins, Transporters Evidence at protein level HPA042139, HPA058526 Uncertain Approved Vesicles Endometrial cancer:9.76e-5 (favourable) Expressed in all Expressed in all testis: 109.9 SLC39A6 LIV-1 ENSG00000141424 Solute carrier family 39 (zinc transporter), member 6 18 36108532-36129385 Predicted membrane proteins, Transporters Evidence at protein level HPA042377 Approved Liver cancer:5.33e-4 (unfavourable) Expressed in all Expressed in all prostate: 209.0 SLC39A7 D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7 ENSG00000112473 Solute carrier family 39 (zinc transporter), member 7 6 33200445-33204439 Predicted membrane proteins, Transporters Evidence at protein level HPA053999 Approved Supported Endoplasmic reticulum Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 40.2 SLC39A9 FLJ11274 ENSG00000029364 Solute carrier family 39, member 9 14 69398015-69462388 Predicted membrane proteins, Transporters Evidence at protein level HPA007921, HPA075390 Approved Approved Endoplasmic reticulum Renal cancer:1.05e-6 (favourable) Expressed in all Expressed in all parathyroid gland,thyroid gland: 44.1 SLC3A2 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE ENSG00000168003 Solute carrier family 3 (amino acid transporter heavy chain), member 2 11 62856102-62888875 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB010455, HPA017980 Supported Supported Nucleus
Plasma membrane
Cytosol Urothelial cancer:1.48e-4 (unfavourable), Liver cancer:8.17e-4 (unfavourable), Renal cancer:8.22e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 424.3 SLC40A1 FPN1, HFE4, IREG1, MTP1, SLC11A3 ENSG00000138449 Solute carrier family 40 (iron-regulated transporter), member 1 2 189560579-189583758 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA065634 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Renal cancer:8.55e-5 (favourable) Expressed in all Expressed in all spleen: 496.0 SLC41A3 FLJ20473 ENSG00000114544 Solute carrier family 41, member 3 3 126006355-126101561 Predicted membrane proteins, Transporters Evidence at protein level HPA045847 Approved Supported Plasma membrane Liver cancer:1.49e-7 (unfavourable), Renal cancer:6.04e-7 (favourable) Expressed in all Expressed in all testis: 79.0 SLC43A1 PB39, POV1, R00504 ENSG00000149150 Solute carrier family 43 (amino acid system L transporter), member 1 11 57484534-57515786 Predicted membrane proteins, Transporters Evidence at protein level HPA018813, HPA018826 Supported Approved Golgi apparatus
Vesicles
Plasma membrane Renal cancer:2.97e-5 (unfavourable), Endometrial cancer:3.19e-4 (favourable), Thyroid cancer:5.27e-4 (unfavourable) Expressed in all Expressed in all liver: 50.0 SLC43A3 DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1 ENSG00000134802 Solute carrier family 43, member 3 11 57406954-57427580 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA030551 Approved Renal cancer:3.97e-13 (unfavourable) Expressed in all Expressed in all thyroid gland: 121.6 SLC44A1 CD92, CDW92, CHTL1, CTL1 ENSG00000070214 Solute carrier family 44 (choline transporter), member 1 9 105244622-105439171 CD markers, Predicted membrane proteins, Transporters Evidence at protein level HPA064714 Supported Nucleoplasm
Mitochondria Renal cancer:1.85e-4 (favourable), Lung cancer:4.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 107.8 SLC44A2 CTL2 ENSG00000129353 Solute carrier family 44 (choline transporter), member 2 19 10602457-10644559 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA003228, HPA070799 Approved Approved Vesicles
Cell Junctions Renal cancer:1.71e-5 (favourable), Pancreatic cancer:6.01e-4 (unfavourable) Expressed in all Expressed in all placenta: 224.3 SLC46A1 HCP1, MGC9564, PCFT ENSG00000076351 Solute carrier family 46 (folate transporter), member 1 17 28394756-28407197 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB011614 Approved Supported Plasma membrane
Cytosol Glioma:3.90e-4 (unfavourable) Expressed in all Expressed in all duodenum: 97.7 SLC46A3 DKFZp686A1775, FLJ42613 ENSG00000139508 Solute carrier family 46, member 3 13 28700064-28718970 Predicted membrane proteins, Transporters Evidence at protein level HPA039930 Uncertain Approved Plasma membrane
Actin filaments
Cytosol Lung cancer:7.09e-4 (favourable) Expressed in all Expressed in all small intestine: 89.4 SLC48A1 FLJ20489, hHRG-1, HRG1 ENSG00000211584 Solute carrier family 48 (heme transporter), member 1 12 47753916-47782753 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA073994 Supported Vesicles Renal cancer:1.34e-6 (favourable), Liver cancer:9.39e-5 (unfavourable), Cervical cancer:4.27e-4 (favourable) Expressed in all Expressed in all thyroid gland: 79.4 SLC4A1AP HLC3, kanadaptin ENSG00000163798 Solute carrier family 4 (anion exchanger), member 1, adaptor protein 2 27663471-27694976 Predicted intracellular proteins, Transporters Evidence at protein level HPA036679 Approved Supported Nucleoplasm
Vesicles Liver cancer:3.76e-7 (unfavourable), Endometrial cancer:1.49e-4 (unfavourable), Urothelial cancer:1.79e-4 (unfavourable) Expressed in all Expressed in all testis: 61.8 SLC4A2 AE2, BND3L, EPB3L1, HKB3, NBND3 ENSG00000164889 Solute carrier family 4 (anion exchanger), member 2 7 151057210-151076527 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA019339 Supported Approved Nuclear speckles
Plasma membrane
Cytosol Liver cancer:9.04e-6 (unfavourable), Renal cancer:1.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 87.8 SLC50A1 HsSWEET1, RAG1AP1, RP11-540D14.5, RZPDo834D038D, SCP, slv, SWEET1 ENSG00000169241 Solute carrier family 50 (sugar efflux transporter), member 1 1 155135344-155138857 Predicted membrane proteins, Transporters Evidence at protein level HPA018095 Approved Renal cancer:3.88e-7 (unfavourable) Expressed in all Expressed in all epididymis: 133.2 SLC52A2 D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2 ENSG00000185803 Solute carrier family 52 (riboflavin transporter), member 2 8 144354135-144361272 Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA063036 Approved Liver cancer:2.04e-6 (unfavourable), Renal cancer:1.23e-4 (unfavourable), Cervical cancer:7.55e-4 (unfavourable) Expressed in all Expressed in all placenta: 24.0 SLC5A6 SMVT ENSG00000138074 Solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2 27199587-27212958 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA036958 Approved Approved Cell Junctions Renal cancer:3.60e-7 (unfavourable) Expressed in all Expressed in all epididymis: 82.1 SLC7A6OS FLJ13291 ENSG00000103061 Solute carrier family 7, member 6 opposite strand 16 68284503-68310951 Predicted intracellular proteins Evidence at protein level HPA041533 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.35e-4 (favourable) Mixed Expressed in all lymph node: 19.3 SLC8B1 FLJ22233, NCKX6, NCLX, SLC24A6 ENSG00000089060 Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 12 113298759-113359493 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA040668 Approved Urothelial cancer:5.02e-4 (favourable), Breast cancer:9.52e-4 (favourable) Expressed in all Expressed in all adrenal gland: 48.6 SLC9A1 APNH, NHE1, PPP1R143 ENSG00000090020 Solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1 27098815-27166981 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB022371, HPA048532, HPA052891 Supported Supported Plasma membrane Glioma:6.32e-4 (unfavourable), Ovarian cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all stomach: 66.4 SLC9A3R1 EBP50, NHERF ENSG00000109062 Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 17 74748652-74769353 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB001962, HPA009672, HPA027247 Supported Approved Vesicles
Plasma membrane
Microtubule organizing center Liver cancer:9.83e-5 (unfavourable) Expressed in all Expressed in all small intestine: 308.5 SLC9A8 KIAA0939, NHE8 ENSG00000197818 Solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 20 49812713-49892242 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level CAB033682 Approved Expressed in all Expressed in all bone marrow: 13.2 SLCO2B1 OATP-B, OATP2B1, SLC21A9 ENSG00000137491 Solute carrier organic anion transporter family, member 2B1 11 75100563-75206549 FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA020659 Uncertain Expressed in all Expressed in all liver: 123.0 SLF2 C10orf6, FAM178A, FLJ10512, FLJ25012 ENSG00000119906 SMC5-SMC6 complex localization factor 2 10 100912569-100965136 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038499, HPA057568 Approved Supported Nucleus
Vesicles Expressed in all Expressed in all epididymis: 56.6 SLFN11 FLJ34922 ENSG00000172716 Schlafen family member 11 17 35350305-35373701 Predicted intracellular proteins Evidence at protein level HPA023030, HPA062062 Uncertain Validated Nucleoplasm Renal cancer:9.93e-10 (unfavourable) Expressed in all Expressed in all lung: 56.1 SLIRP C14orf156, DC50 ENSG00000119705 SRA stem-loop interacting RNA binding protein 14 77708071-77761104 Predicted intracellular proteins Evidence at protein level HPA020291 Approved Supported Mitochondria Head and neck cancer:4.88e-4 (unfavourable) Expressed in all Expressed in all epididymis: 202.0 SLK KIAA0204, se20-9, STK2 ENSG00000065613 STE20-like kinase 10 103967201-104029233 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015757 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:2.77e-5 (unfavourable), Renal cancer:3.95e-5 (favourable) Expressed in all Expressed in all esophagus: 61.2 SLMAP KIAA1601, SLAP ENSG00000163681 Sarcolemma associated protein 3 57755450-57929168 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002357, HPA002358 Supported Approved Endoplasmic reticulum Renal cancer:1.58e-6 (favourable), Lung cancer:7.98e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 262.4 SLTM FLJ13213, Met ENSG00000137776 SAFB-like, transcription modulator 15 58879045-58933653 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040256, HPA040381 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 65.6 SLU7 9G8 ENSG00000164609 SLU7 homolog, splicing factor 5 160401641-160421711 Predicted intracellular proteins Evidence at protein level HPA035907, HPA058120 Uncertain Validated Nucleoplasm
Nuclear speckles Renal cancer:1.98e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 50.3 SLX1A GIYD1 ENSG00000132207 SLX1 homolog A, structure-specific endonuclease subunit 16 30193887-30197561 Predicted intracellular proteins Evidence at protein level HPA047038 Uncertain Approved Nucleoplasm Not detected Expressed in all duodenum: 51.8 SMAD1 JV4-1, MADH1, MADR1 ENSG00000170365 SMAD family member 1 4 145481194-145558079 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005389 Approved Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 69.4 SMAD2 JV18-1, MADH2, MADR2 ENSG00000175387 SMAD family member 2 18 47808957-47931146 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB025507, HPA067203, CAB073546 Approved Supported Nucleus
Nucleoli
Cytosol Liver cancer:9.44e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 126.1 SMAD3 HsT17436, JV15-2, MADH3 ENSG00000166949 SMAD family member 3 15 67063763-67195195 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB008094, HPA046386, HPA067203, CAB069409 Approved Validated Nucleoplasm
Cytosol Pancreatic cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all esophagus: 54.4 SMAD4 DPC4, MADH4 ENSG00000141646 SMAD family member 4 18 51028394-51085045 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019154 Approved Supported Nucleoplasm
Centrosome
Cytosol Renal cancer:1.92e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 38.7 SMAD5 Dwfc, JV5-1, MADH5 ENSG00000113658 SMAD family member 5 5 136132845-136188747 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA058931 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all endometrium: 42.9 SMAD7 MADH7, MADH8 ENSG00000101665 SMAD family member 7 18 48919853-48950711 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB026212, HPA028897 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:5.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.1 SMAP1 FLJ13159, SMAP-1 ENSG00000112305 Small ArfGAP 1 6 70667776-70862015 Predicted intracellular proteins Evidence at protein level HPA030574 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 51.1 SMAP2 SMAP1L ENSG00000084070 Small ArfGAP2 1 40344850-40423326 Predicted intracellular proteins Evidence at protein level HPA021466, HPA024424 Approved Head and neck cancer:5.34e-5 (favourable), Liver cancer:2.53e-4 (unfavourable), Cervical cancer:6.55e-4 (favourable) Expressed in all Expressed in all lymph node: 235.7 SMARCA2 BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2 ENSG00000080503 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 9 2015219-2193624 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA029981, CAB037276 Supported Approved Nucleoplasm
Vesicles
Intermediate filaments Renal cancer:1.26e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 353.9 SMARCA4 BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2 ENSG00000127616 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 19 10961001-11065395 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004208 Supported Supported Nucleoplasm Liver cancer:1.11e-4 (unfavourable) Expressed in all Expressed in all testis: 39.5 SMARCA5 hISWI, hSNF2H, ISWI ENSG00000153147 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 4 143513463-143557486 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005227, HPA008751 Supported Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all testis: 59.0 SMARCAD1 DKFZP762K2015, ETL1, KIAA1122 ENSG00000163104 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 4 94207611-94291292 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA016737 Approved Validated Nucleoplasm Liver cancer:3.22e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.5 SMARCAL1 HARP, HHARP ENSG00000138375 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2 216412414-216483053 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020337 Uncertain Supported Nucleoplasm Liver cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all ovary: 19.7 SMARCB1 BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1 ENSG00000099956 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 22 23786963-23834516 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009196, HPA018248, HPA019127 Supported Supported Nucleoplasm
Nucleoli fibrillar center Renal cancer:1.14e-6 (favourable), Liver cancer:6.52e-4 (unfavourable) Expressed in all Expressed in all testis: 51.2 SMARCC1 BAF155, CRACC1, Rsc8, SRG3 ENSG00000173473 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 3 47585272-47782106 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB011576, CAB016336, HPA024352, HPA026853 Supported Validated Nucleoplasm Colorectal cancer:3.34e-4 (favourable), Liver cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all prostate: 35.6 SMARCC2 BAF170, CRACC2, Rsc8 ENSG00000139613 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 12 56162983-56189567 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004321, HPA021213, HPA061788 Supported Validated Nucleoplasm Expressed in all Expressed in all cerebral cortex: 77.0 SMARCD1 BAF60A, CRACD1, Rsc6p ENSG00000066117 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 12 50084972-50100712 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA004101 Supported Approved Nucleoplasm
Vesicles Liver cancer:2.53e-8 (unfavourable) Expressed in all Expressed in all parathyroid gland: 84.7 SMARCD2 BAF60B, CRACD2, PRO2451, Rsc6p ENSG00000108604 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 17 63832081-63843065 Predicted intracellular proteins Evidence at protein level HPA059934, HPA061348 Validated Nucleoplasm Melanoma:3.51e-4 (unfavourable), Renal cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all skin: 104.9 SMARCE1 BAF57 ENSG00000073584 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 17 40624962-40648508 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003916, CAB037318 Supported Supported Nucleoplasm Expressed in all Expressed in all endometrium: 72.9 SMC1A DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb ENSG00000072501 Structural maintenance of chromosomes 1A X 53374149-53422728 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005499, CAB025404 Supported Validated Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 51.8 SMC3 BAM, bamacan, CSPG6, HCAP, SMC3L1 ENSG00000108055 Structural maintenance of chromosomes 3 10 110567691-110604636 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037411, HPA043206 Uncertain Supported Nucleoplasm Expressed in all Expressed in all testis: 94.5 SMC5 KIAA0594, SMC5L1 ENSG00000198887 Structural maintenance of chromosomes 5 9 70258962-70354888 Predicted intracellular proteins Evidence at protein level HPA054900 Supported Supported Nuclear speckles Expressed in all Expressed in all ovary: 30.8 SMC6 FLJ22116, SMC6L1 ENSG00000163029 Structural maintenance of chromosomes 6 2 17663812-17800242 Predicted intracellular proteins Evidence at protein level HPA035057, CAB037186, HPA042733 Uncertain Supported Nucleoplasm Renal cancer:3.15e-4 (unfavourable) Expressed in all Expressed in all testis: 64.5 SMCHD1 KIAA0650 ENSG00000101596 Structural maintenance of chromosomes flexible hinge domain containing 1 18 2655738-2805017 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039441 Approved Approved Nucleoplasm
Nuclear bodies Renal cancer:1.40e-4 (unfavourable), Liver cancer:5.39e-4 (unfavourable) Expressed in all Expressed in all spleen: 41.1 SMCO4 C11orf75, FN5 ENSG00000166002 Single-pass membrane protein with coiled-coil domains 4 11 93478472-93543508 Predicted membrane proteins Evidence at protein level HPA041120 Uncertain Renal cancer:5.81e-7 (unfavourable) Expressed in all Expressed in all salivary gland: 98.0 SMCR8 FLJ34716 ENSG00000176994 Smith-Magenis syndrome chromosome region, candidate 8 17 18315310-18328055 Predicted intracellular proteins Evidence at protein level HPA021557, HPA024646 Uncertain Validated Nucleoplasm Renal cancer:1.35e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.8 SMDT1 C22orf32, DDDD, dJ186O1.1, EMRE ENSG00000183172 Single-pass membrane protein with aspartate-rich tail 1 22 42079691-42084284 Predicted membrane proteins, Transporters Evidence at protein level HPA032117, HPA060340 Uncertain Supported Nucleus
Mitochondria Renal cancer:2.36e-9 (favourable), Endometrial cancer:5.32e-8 (favourable), Pancreatic cancer:5.87e-4 (favourable) Expressed in all Expressed in all thyroid gland: 7.8 SMG1 ATX, KIAA0421, LIP ENSG00000157106 SMG1 phosphatidylinositol 3-kinase-related kinase 16 18804853-18926454 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006870, HPA031623, HPA073972 Approved Supported Nucleoplasm Expressed in all Expressed in all skin: 50.3 SMG5 EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5 ENSG00000198952 SMG5 nonsense mediated mRNA decay factor 1 156249224-156282825 Predicted membrane proteins Evidence at protein level HPA072651 Supported Cytoplasmic bodies Liver cancer:6.70e-9 (unfavourable), Endometrial cancer:3.39e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 74.7 SMG6 C17orf31, EST1A, KIAA0732, SMG-6 ENSG00000070366 SMG6 nonsense mediated mRNA decay factor 17 2059839-2303771 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042932 Approved Supported Nucleoli
Cytosol Renal cancer:1.30e-6 (favourable) Expressed in all Expressed in all ovary: 47.4 SMG7 C1orf16, EST1C, KIAA0250, SGA56M, SMG-7 ENSG00000116698 SMG7 nonsense mediated mRNA decay factor 1 183472216-183598246 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029350 Supported Supported Intermediate filaments
Cytosol Expressed in all Expressed in all testis: 122.5 SMG8 C17orf71, FLJ10587, FLJ23205 ENSG00000167447 SMG8 nonsense mediated mRNA decay factor 17 59209400-59215247 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024841 Approved Approved Nucleoplasm Liver cancer:3.72e-5 (unfavourable) Expressed in all Expressed in all testis: 13.9 SMIM11B ENSG00000273590 Small integral membrane protein 11B 21 7744962-7777853 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA051321 Uncertain Approved Focal adhesion sites Not detected Expressed in all epididymis: 25.9 SMIM12 C1orf212, FLJ90372 ENSG00000163866 Small integral membrane protein 12 1 34712737-34859816 Predicted membrane proteins Evidence at protein level HPA065331 Approved Approved Mitochondria Renal cancer:1.15e-5 (favourable), Liver cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 44.8 SMIM14 C4orf34, FLJ13289 ENSG00000163683 Small integral membrane protein 14 4 39546330-39639090 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051299 Uncertain Approved Mitochondria Head and neck cancer:3.00e-6 (favourable), Renal cancer:2.07e-4 (favourable), Endometrial cancer:2.63e-4 (favourable), Liver cancer:3.47e-4 (favourable) Expressed in all Expressed in all liver: 54.1 SMIM15 C5orf43, DKFZP686E2158 ENSG00000188725 Small integral membrane protein 15 5 61157709-61162474 Predicted intracellular proteins Evidence at protein level Urothelial cancer:9.23e-4 (favourable) Expressed in all Expressed in all thyroid gland: 59.7 SMIM19 C8orf40 ENSG00000176209 Small integral membrane protein 19 8 42541155-42555193 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA011145 Uncertain Renal cancer:1.74e-6 (favourable) Expressed in all Expressed in all thyroid gland: 122.6 SMIM20 C4orf52 ENSG00000250317 Small integral membrane protein 20 4 25861830-25929874 Predicted membrane proteins Evidence at protein level HPA016552 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:8.97e-5 (favourable) Expressed in all Expressed in all epididymis: 86.3 SMIM3 C5orf62, MSTP150, NID67 ENSG00000256235 Small integral membrane protein 3 5 150777946-150796734 Predicted membrane proteins Evidence at protein level HPA075345 Approved Vesicles Renal cancer:1.15e-8 (unfavourable) Expressed in all Expressed in all adipose tissue: 108.7 SMIM4 C3orf78 ENSG00000168273 Small integral membrane protein 4 3 52534013-52579237 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047771 Uncertain Approved Nucleoplasm
Mitochondria Lung cancer:1.78e-5 (favourable), Renal cancer:1.63e-4 (favourable), Pancreatic cancer:5.00e-4 (favourable) Expressed in all Expressed in all adrenal gland: 102.7 SMIM7 C19orf42, MGC2747 ENSG00000214046 Small integral membrane protein 7 19 16630751-16660442 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA043127 Uncertain Approved Golgi apparatus Expressed in all Expressed in all epididymis: 55.0 SMNDC1 SMNR, SPF30, TDRD16C ENSG00000119953 Survival motor neuron domain containing 1 10 110290730-110304951 Predicted intracellular proteins Evidence at protein level HPA061214 Supported Nucleus
Nuclear bodies Liver cancer:8.08e-6 (unfavourable), Pancreatic cancer:7.20e-4 (unfavourable) Expressed in all Expressed in all placenta: 26.1 SMPD1 ASM ENSG00000166311 Sphingomyelin phosphodiesterase 1, acid lysosomal 11 6390431-6394998 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level Renal cancer:4.57e-6 (favourable), Glioma:1.09e-4 (unfavourable), Pancreatic cancer:7.47e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 62.3 SMPD4 FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3 ENSG00000136699 Sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2 130151392-130182750 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA046279, HPA049426 Approved Approved Nuclear membrane
Cytosol Renal cancer:8.16e-8 (unfavourable), Liver cancer:8.37e-6 (unfavourable), Endometrial cancer:7.47e-5 (unfavourable), Prostate cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all testis: 36.3 SMPDL3A ASM3A, ASML3a, FLJ20177, yR36GH4.1 ENSG00000172594 Sphingomyelin phosphodiesterase, acid-like 3A 6 122789049-122809720 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA030148 Uncertain Approved Nucleus
Nucleoli
Mitochondria Colorectal cancer:6.11e-4 (favourable) Expressed in all Expressed in all small intestine: 83.5 SMS MRSR, SPMSY, SpS, SRS ENSG00000102172 Spermine synthase X 21940573-21994835 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA029849, HPA029852 Approved Approved Nuclear bodies
Cytosol Liver cancer:7.79e-8 (unfavourable), Renal cancer:7.85e-5 (unfavourable), Head and neck cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all prostate: 214.9 SMTN ENSG00000183963 Smoothelin 22 31064105-31104757 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001721, HPA051778, HPA058590 Supported Validated Nucleoplasm
Actin filaments Renal cancer:2.73e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 252.4 SMU1 BWD, FLJ10805, fSAP57, SMU-1 ENSG00000122692 Smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 9 33041764-33076659 Predicted intracellular proteins Evidence at protein level HPA019228, HPA019708 Supported Approved Vesicles Renal cancer:1.67e-5 (favourable), Ovarian cancer:1.25e-4 (favourable), Cervical cancer:2.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.1 SMUG1 FDG, HMUDG, UNG3 ENSG00000123415 Single-strand-selective monofunctional uracil-DNA glycosylase 1 12 54121277-54189008 Predicted intracellular proteins Evidence at protein level HPA051149, HPA071486 Approved Vesicles
Centrosome Ovarian cancer:1.31e-4 (favourable), Liver cancer:6.96e-4 (unfavourable) Expressed in all Expressed in all epididymis: 47.9 SMURF1 KIAA1625 ENSG00000198742 SMAD specific E3 ubiquitin protein ligase 1 7 99027438-99144100 Predicted intracellular proteins Evidence at protein level HPA055245 Approved Expressed in all Expressed in all testis: 45.9 SMYD2 HSKM-B, KMT3C, ZMYND14 ENSG00000143499 SET and MYND domain containing 2 1 214281102-214337131 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029023 Uncertain Approved Intermediate filaments
Mitochondria
Cytosol Cervical cancer:1.53e-5 (unfavourable), Renal cancer:8.68e-4 (favourable) Expressed in all Expressed in all heart muscle: 126.2 SMYD3 KMT3E, ZMYND1, ZNFN3A1 ENSG00000185420 SET and MYND domain containing 3 1 245749342-246507312 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB012229, HPA045821, HPA054352 Approved Approved Golgi apparatus
Vesicles Expressed in all Expressed in all thyroid gland: 26.9 SMYD4 KIAA1936, ZMYND21 ENSG00000186532 SET and MYND domain containing 4 17 1779485-1830634 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030059 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles
Cytosol Expressed in all Expressed in all testis: 10.9 SMYD5 NN8-4AG, RAI15, RRG1, ZMYND23 ENSG00000135632 SMYD family member 5 2 73214222-73227237 Predicted intracellular proteins Evidence at protein level HPA015514, HPA049002 Uncertain Approved Mitochondria Liver cancer:6.58e-7 (unfavourable) Expressed in all Expressed in all ovary: 34.1 SNAP23 HsT17016, SNAP23A, SNAP23B ENSG00000092531 Synaptosomal-associated protein, 23kDa 15 42491233-42545356 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA001214, CAB037083, CAB037317 Approved Supported Plasma membrane Expressed in all Expressed in all spleen: 88.1 SNAP29 CEDNIK, SNAP-29 ENSG00000099940 Synaptosomal-associated protein, 29kDa 22 20858983-20891218 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031823, CAB037092, HPA056492 Supported Supported Nucleoplasm
Cytosol Cervical cancer:6.99e-4 (favourable) Expressed in all Expressed in all testis: 74.3 SNAP47 C1orf142, SNAP-47, SVAP1 ENSG00000143740 Synaptosomal-associated protein, 47kDa 1 227728539-227781231 Predicted intracellular proteins Evidence at protein level HPA028167 Supported Approved Cytosol Expressed in all Expressed in all testis: 56.5 SNAPC2 PTFdelta, SNAP45 ENSG00000104976 Small nuclear RNA activating complex, polypeptide 2, 45kDa 19 7920316-7923250 Predicted intracellular proteins Evidence at protein level HPA049843 Supported Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:4.89e-5 (unfavourable) Expressed in all Expressed in all endometrium: 30.8 SNAPC4 FLJ13451, PTFalpha, SNAP190 ENSG00000165684 Small nuclear RNA activating complex, polypeptide 4, 190kDa 9 136375577-136398797 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046627, HPA073243 Uncertain Approved Nucleoplasm
Nuclear membrane Pancreatic cancer:4.52e-5 (favourable) Expressed in all Expressed in all testis: 14.1 SNAPC5 SNAP19 ENSG00000174446 Small nuclear RNA activating complex, polypeptide 5, 19kDa 15 66490135-66497813 Predicted intracellular proteins Evidence at protein level HPA024379 Uncertain Supported Nucleus Expressed in all Expressed in all testis: 63.6 SNAPIN BLOC1S7, BORCS3, SNAPAP ENSG00000143553 SNAP-associated protein 1 153658654-153661830 Predicted intracellular proteins, Transporters Evidence at protein level HPA046974 Approved Approved Nucleoli
Golgi apparatus Renal cancer:5.42e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 41.8 SND1 p100, TDRD11 ENSG00000197157 Staphylococcal nuclease and tudor domain containing 1 7 127652180-128092609 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002529, HPA002632, CAB019323 Supported Validated Cytosol Endometrial cancer:1.95e-4 (favourable) Expressed in all Expressed in all placenta: 121.5 SNF8 Dot3, EAP30, VPS22 ENSG00000159210 SNF8, ESCRT-II complex subunit 17 48929316-48945117 Predicted intracellular proteins Evidence at protein level HPA059320 Approved Supported Nucleoplasm
Cytosol Renal cancer:2.81e-7 (unfavourable), Liver cancer:7.64e-4 (unfavourable) Expressed in all Expressed in all epididymis: 42.7 SNN ENSG00000184602 Stannin 16 11668414-11679159 Predicted membrane proteins Evidence at protein level HPA011055 Approved Approved Cytosol Liver cancer:1.85e-6 (unfavourable), Renal cancer:1.83e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 151.1 SNRK FLJ20224, HSNFRK, KIAA0096 ENSG00000163788 SNF related kinase 3 43286512-43424764 Enzymes, Predicted intracellular proteins Evidence at protein level HPA042163 Uncertain Approved Nucleus
Vesicles
Plasma membrane
Cell Junctions Renal cancer:9.41e-5 (favourable), Breast cancer:9.28e-4 (favourable) Expressed in all Expressed in all placenta: 47.5 SNRNP200 ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD ENSG00000144028 Small nuclear ribonucleoprotein 200kDa (U5) 2 96274336-96305515 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA029321 Approved Supported Nucleoplasm Endometrial cancer:3.89e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 114.3 SNRNP25 C16orf33 ENSG00000161981 Small nuclear ribonucleoprotein 25kDa (U11/U12) 16 53010-57669 Predicted intracellular proteins Evidence at protein level HPA041183, HPA044248 Uncertain Supported Nucleoplasm
Cytokinetic bridge
Cytosol Renal cancer:1.16e-5 (favourable), Cervical cancer:1.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 55.6 SNRNP27 RY1 ENSG00000124380 Small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2 69893560-69905575 Predicted intracellular proteins Evidence at protein level HPA034541 Approved Approved Nucleoplasm Endometrial cancer:2.33e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.5 SNRNP35 U1SNRNPBP ENSG00000184209 Small nuclear ribonucleoprotein 35kDa (U11/U12) 12 123457641-123473154 Predicted intracellular proteins Evidence at protein level HPA059145, HPA067031 Supported Supported Nucleoli Expressed in all Expressed in all parathyroid gland: 33.9 SNRNP40 HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57 ENSG00000060688 Small nuclear ribonucleoprotein 40kDa (U5) 1 31259568-31296782 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026527, HPA027345 Supported Supported Nuclear speckles Liver cancer:4.73e-6 (unfavourable), Glioma:9.74e-4 (favourable) Expressed in all Expressed in all lymph node: 41.5 SNRNP70 RNPU1Z, RPU1, Snp1, SNRP70, U1-70K ENSG00000104852 Small nuclear ribonucleoprotein 70kDa (U1) 19 49085419-49108605 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001718, HPA042050, HPA043516 Supported Validated Nucleoplasm Pancreatic cancer:4.59e-5 (favourable), Urothelial cancer:5.35e-5 (favourable), Renal cancer:6.12e-5 (unfavourable) Expressed in all Expressed in all endometrium: 59.8 SNRPA Mud1, U1-A, U1A ENSG00000077312 Small nuclear ribonucleoprotein polypeptide A 19 40750637-40765389 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004652, HPA046440, HPA054834 Supported Validated Nucleoplasm Renal cancer:2.96e-9 (unfavourable), Liver cancer:1.34e-5 (unfavourable), Cervical cancer:2.50e-4 (favourable) Expressed in all Expressed in all lymph node: 61.5 SNRPA1 Lea1 ENSG00000131876 Small nuclear ribonucleoprotein polypeptide A' 15 101281510-101295282 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045622, HPA048499 Supported Validated Nuclear speckles Renal cancer:0.00e+0 (unfavourable), Liver cancer:8.56e-5 (unfavourable), Ovarian cancer:8.83e-5 (favourable) Expressed in all Expressed in all testis: 68.2 SNRPB COD, Sm-B/B', SmB/SmB', snRNP-B, SNRPB1 ENSG00000125835 Small nuclear ribonucleoprotein polypeptides B and B1 20 2461634-2470853 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003482, CAB009610, HPA067842 Approved Supported Nucleoplasm Liver cancer:1.07e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 202.5 SNRPB2 Msl1 ENSG00000125870 Small nuclear ribonucleoprotein polypeptide B 20 16729961-16742563 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050814 Supported Nuclear speckles Liver cancer:6.03e-7 (unfavourable), Renal cancer:2.79e-4 (unfavourable), Endometrial cancer:7.57e-4 (unfavourable) Expressed in all Expressed in all lymph node: 50.5 SNRPC U1-C, Yhc1 ENSG00000124562 Small nuclear ribonucleoprotein polypeptide C 6 34757406-34773794 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034338, HPA042419, HPA055490 Supported Validated Nucleoplasm Renal cancer:8.20e-5 (unfavourable), Liver cancer:5.65e-4 (unfavourable) Expressed in all Expressed in all testis: 150.7 SNRPD1 HsT2456, Sm-D1, SNRPD ENSG00000167088 Small nuclear ribonucleoprotein D1 polypeptide 16kDa 18 21612267-21633524 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040516 Supported Ovarian cancer:7.90e-6 (favourable), Liver cancer:1.82e-5 (unfavourable) Expressed in all Expressed in all lymph node: 82.3 SNRPD2 Sm-D2, SNRPD1 ENSG00000125743 Small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 19 45687454-45692569 Predicted intracellular proteins Evidence at protein level HPA041437 Supported Uncertain Cytosol Renal cancer:8.58e-5 (unfavourable) Expressed in all Expressed in all ovary: 334.1 SNRPD3 Sm-D3, SMD3 ENSG00000100028 Small nuclear ribonucleoprotein D3 polypeptide 18kDa 22 24555503-24609980 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001170 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all thyroid gland: 77.8 SNRPE Sm-E ENSG00000182004 Small nuclear ribonucleoprotein polypeptide E 1 203861603-203870550 Disease related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.38e-5 (unfavourable), Ovarian cancer:3.95e-4 (favourable) Expressed in all Expressed in all breast: 96.4 SNRPF Sm-F ENSG00000139343 Small nuclear ribonucleoprotein polypeptide F 12 95858928-95903828 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.11e-6 (unfavourable) Expressed in all Expressed in all appendix: 38.1 SNRPG Sm-G ENSG00000143977 Small nuclear ribonucleoprotein polypeptide G 2 70281362-70293771 Predicted intracellular proteins Evidence at protein level HPA064152, HPA067814 Supported Approved Nucleoplasm Renal cancer:1.08e-6 (unfavourable) Expressed in all Expressed in all epididymis: 114.2 SNRPN HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN ENSG00000128739 Small nuclear ribonucleoprotein polypeptide N 15 24823637-24978723 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003482, HPA067842 Approved Supported Nucleoplasm Renal cancer:8.93e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 516.6 SNTA1 LQT12, SNT1, TACIP1 ENSG00000101400 Syntrophin, alpha 1 20 33407955-33443892 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB037059 Approved Endometrial cancer:9.60e-6 (unfavourable), Pancreatic cancer:3.72e-4 (favourable), Melanoma:7.08e-4 (favourable) Expressed in all Expressed in all thyroid gland: 101.8 SNU13 15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1 ENSG00000100138 SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) 22 41673930-41690504 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA029199 Uncertain Expressed in all Expressed in all adrenal gland: 168.4 SNUPN RNUT1, SNURPORTIN-1, Snurportin1 ENSG00000169371 Snurportin 1 15 75598083-75626469 Predicted intracellular proteins Evidence at protein level CAB005004 Approved Supported Nuclear membrane Expressed in all Expressed in all testis: 54.0 SNURF ENSG00000273173 SNRPN upstream reading frame 15 24954986-24977850 Predicted intracellular proteins Evidence at protein level HPA065733 Approved Nuclear speckles Mixed Expressed in all cerebral cortex: 197.2 SNW1 Bx42, NCoA-62, Prp45, PRPF45, SKIIP, SKIP ENSG00000100603 SNW domain containing 1 14 77717599-77761207 Predicted intracellular proteins Evidence at protein level HPA002457, CAB009931, HPA017370 Supported Validated Nucleoplasm Liver cancer:1.96e-4 (unfavourable) Expressed in all Expressed in all testis: 84.7 SNX1 HsT17379, MGC8664, SNX1A, Vps5 ENSG00000028528 Sorting nexin 1 15 64094123-64146090 Predicted intracellular proteins Evidence at protein level HPA047373, HPA052761 Approved Validated Endosomes
Lysosomes Renal cancer:9.88e-6 (favourable) Expressed in all Expressed in all thyroid gland: 162.7 SNX11 ENSG00000002919 Sorting nexin 11 17 48103357-48123074 Predicted intracellular proteins Evidence at protein level HPA044787, HPA054660 Approved Approved Cytosol Expressed in all Expressed in all thyroid gland: 32.0 SNX12 ENSG00000147164 Sorting nexin 12 X 71056332-71073426 Predicted intracellular proteins Evidence at protein level CAB070423 Approved Renal cancer:1.51e-7 (favourable), Endometrial cancer:1.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.0 SNX13 KIAA0713, RGS-PX1 ENSG00000071189 Sorting nexin 13 7 17790761-17940501 Predicted membrane proteins Evidence at protein level Renal cancer:5.98e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 31.7 SNX14 RGS-PX2 ENSG00000135317 Sorting nexin 14 6 85505496-85594156 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017639 Approved Supported Cytosol Head and neck cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all testis: 154.6 SNX15 ENSG00000110025 Sorting nexin 15 11 65027408-65040572 Predicted intracellular proteins Evidence at protein level HPA038955 Approved Supported Nucleoli
Cytosol Not detected Expressed in all cerebral cortex: 24.8 SNX17 KIAA0064 ENSG00000115234 Sorting nexin 17 2 27370496-27377533 Predicted intracellular proteins Evidence at protein level HPA043867 Supported Supported Vesicles Expressed in all Expressed in all fallopian tube: 96.8 SNX18 SH3PX2, SH3PXD3B, SNAG1 ENSG00000178996 Sorting nexin 18 5 54517759-54546585 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037800 Approved Approved Cytosol Renal cancer:1.58e-4 (favourable) Expressed in all Expressed in all bone marrow: 42.9 SNX19 CHET8, KIAA0254 ENSG00000120451 Sorting nexin 19 11 130875436-130916509 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013447 Uncertain Supported Mitochondria Renal cancer:3.56e-5 (favourable) Expressed in all Expressed in all testis: 51.6 SNX2 ENSG00000205302 Sorting nexin 2 5 122774996-122830108 Predicted intracellular proteins Evidence at protein level HPA037400 Approved Validated Endosomes
Lysosomes Renal cancer:8.76e-7 (favourable), Liver cancer:7.90e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 123.8 SNX24 SBBI31 ENSG00000064652 Sorting nexin 24 5 122843439-123029354 Predicted intracellular proteins Evidence at protein level HPA044566, HPA073934 Approved Approved Vesicles Endometrial cancer:7.93e-6 (unfavourable), Renal cancer:1.28e-4 (favourable), Liver cancer:8.88e-4 (unfavourable) Expressed in all Expressed in all esophagus: 39.5 SNX25 SBBI31 ENSG00000109762 Sorting nexin 25 4 185204237-185370185 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA036928 Uncertain Approved Vesicles Expressed in all Expressed in all lung: 42.7 SNX27 KIAA0488, MGC20471, MY014 ENSG00000143376 Sorting nexin family member 27 1 151612065-151699091 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA045816 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 18.8 SNX3 Grd19 ENSG00000112335 Sorting nexin 3 6 108211222-108261260 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Breast cancer:4.37e-5 (unfavourable), Renal cancer:2.30e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 290.0 SNX4 ATG24B ENSG00000114520 Sorting nexin 4 3 125446644-125520197 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005709 Uncertain Renal cancer:5.01e-5 (favourable), Endometrial cancer:6.10e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 75.1 SNX5 ENSG00000089006 Sorting nexin 5 20 17941597-17968980 Predicted intracellular proteins Evidence at protein level CAB020679, HPA051187 Approved Approved Nucleoli
Cytosol Liver cancer:2.30e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 132.0 SNX6 ENSG00000129515 Sorting nexin 6 14 34561094-34630183 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049374 Approved Supported Endosomes
Lysosomes Liver cancer:1.25e-4 (unfavourable), Pancreatic cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 216.6 SNX8 Mvp1 ENSG00000106266 Sorting nexin 8 7 2251770-2354318 Predicted intracellular proteins Evidence at protein level HPA057296, HPA060194 Approved Supported Vesicles Liver cancer:8.47e-6 (unfavourable) Expressed in all Expressed in all spleen: 38.7 SNX9 SDP1, SH3PX1, SH3PXD3A ENSG00000130340 Sorting nexin 9 6 157700387-157945077 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031410, HPA057203 Approved Validated Plasma membrane
Cytosol Lung cancer:3.77e-4 (unfavourable), Cervical cancer:5.95e-4 (unfavourable), Renal cancer:9.95e-4 (favourable) Expressed in all Expressed in all gallbladder: 71.1 SOCS2 CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2 ENSG00000120833 Suppressor of cytokine signaling 2 12 93569814-93583487 Predicted intracellular proteins Evidence at protein level CAB010356 Approved Approved Endoplasmic reticulum Pancreatic cancer:8.17e-7 (favourable), Liver cancer:1.09e-6 (favourable) Expressed in all Expressed in all smooth muscle: 129.0 SOCS5 CIS6, Cish5, CISH6, KIAA0671, SOCS-5 ENSG00000171150 Suppressor of cytokine signaling 5 2 46698952-46763129 Predicted intracellular proteins Evidence at protein level HPA020884, CAB025510 Approved Approved Nucleoplasm
Plasma membrane
Cytosol Liver cancer:7.28e-4 (unfavourable), Ovarian cancer:7.53e-4 (unfavourable) Expressed in all Expressed in all ovary: 31.0 SOCS6 CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4 ENSG00000170677 Suppressor of cytokine signaling 6 18 70288901-70330200 Predicted intracellular proteins Evidence at protein level CAB010189 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:1.02e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 29.4 SOD1 ALS, ALS1, IPOA ENSG00000142168 Superoxide dismutase 1, soluble 21 31659622-31668931 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001401, CAB008670 Supported Supported Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all liver: 767.7 SOD2 ENSG00000112096 Superoxide dismutase 2, mitochondrial 6 159669057-159762529 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001814, CAB002013 Supported Renal cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all appendix: 750.9 SON BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP ENSG00000159140 SON DNA binding protein 21 33542618-33577481 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA023535, HPA031755, HPA031756 Supported Validated Nuclear speckles Expressed in all Expressed in all parathyroid gland: 220.0 SORBS1 CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12 ENSG00000095637 Sorbin and SH3 domain containing 1 10 95311771-95561414 Predicted intracellular proteins Evidence at protein level HPA027559, HPA043084 Approved Supported Plasma membrane
Focal adhesion sites
Centrosome Breast cancer:2.84e-4 (favourable) Expressed in all Expressed in all adipose tissue: 318.9 SORBS3 SCAM-1, SH3D4, vinexin ENSG00000120896 Sorbin and SH3 domain containing 3 8 22544986-22575788 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015849, HPA048034 Approved Approved Nucleoplasm
Focal adhesion sites Urothelial cancer:1.53e-5 (unfavourable), Pancreatic cancer:4.88e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 95.0 SORD ENSG00000140263 Sorbitol dehydrogenase 15 45023104-45077185 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040260, HPA040621 Supported Approved Cytosol Liver cancer:6.14e-5 (favourable) Expressed in all Expressed in all cervix, uterine: 401.6 SORT1 Gp95, NT3 ENSG00000134243 Sortilin 1 1 109309568-109397951 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA006889, CAB011498 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Colorectal cancer:7.74e-6 (favourable), Liver cancer:1.23e-4 (unfavourable) Expressed in all Expressed in all epididymis: 166.9 SOS1 GF1, GINGF, HGF ENSG00000115904 Son of sevenless homolog 1 (Drosophila) 2 38981396-39124345 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB005396, HPA012613 Uncertain Uncertain Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all parathyroid gland: 40.3 SOS2 ENSG00000100485 Son of sevenless homolog 2 (Drosophila) 14 50117120-50231558 Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004577, HPA047368, HPA052689 Approved Approved Nucleoplasm
Vesicles Renal cancer:8.48e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 79.3 SOX4 ENSG00000124766 SRY (sex determining region Y)-box 4 6 21592769-21598619 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029901 Approved Supported Nucleoplasm
Mitochondria Liver cancer:2.57e-5 (unfavourable) Expressed in all Expressed in all endometrium: 80.4 SP1 ENSG00000185591 Sp1 transcription factor 12 53380176-53416446 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB000330, HPA001853, HPA012292 Supported Validated Nucleoplasm Pancreatic cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all endometrium: 53.9 SP100 ENSG00000067066 SP100 nuclear antigen 2 230415942-230544090 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016707, HPA017384 Supported Supported Nucleus
Nuclear bodies Renal cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 139.9 SP110 IFI41, IFI75 ENSG00000135899 SP110 nuclear body protein 2 230167293-230225729 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA047036, HPA058554 Approved Supported Nucleus Renal cancer:1.17e-5 (unfavourable) Expressed in all Expressed in all spleen: 64.1 SP2 KIAA0048 ENSG00000167182 Sp2 transcription factor 17 47896150-47928957 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003357, CAB010245 Supported Validated Nucleoplasm
Vesicles Renal cancer:1.82e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 31.3 SP3 SPR-2 ENSG00000172845 Sp3 transcription factor 2 173906459-173965702 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004580, HPA032145 Approved Supported Renal cancer:2.46e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 79.3 SPAG16 DKFZp666P1710, FLJ22724, PF20, WDR29 ENSG00000144451 Sperm associated antigen 16 2 213284379-214410501 Predicted intracellular proteins Evidence at protein level HPA037542 Uncertain Approved Plasma membrane
Cytosol Renal cancer:3.82e-4 (favourable), Prostate cancer:4.90e-4 (unfavourable) Expressed in all Expressed in all testis: 83.8 SPAG7 ACRP, FSA-1, MGC20134 ENSG00000091640 Sperm associated antigen 7 17 4959226-4967872 Predicted intracellular proteins Evidence at protein level HPA024032, HPA052394 Uncertain Supported Nucleus Renal cancer:5.79e-5 (favourable) Expressed in all Expressed in all fallopian tube: 102.0 SPAG9 CT89, FLJ13450, FLJ14006, FLJ26141, FLJ34602, HLC4, HSS, JLP, KIAA0516, MGC117291, MGC14967, MGC74461, PHET, PIG6, SYD1 ENSG00000008294 Sperm associated antigen 9 17 50962174-51120865 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040446, HPA061458 Approved Validated Microtubule organizing center
Cytosol Urothelial cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 106.4 SPARC ON ENSG00000113140 Secreted protein, acidic, cysteine-rich (osteonectin) 5 151661096-151687165 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002306, HPA002989, HPA003020 Supported Renal cancer:3.53e-5 (unfavourable) Expressed in all Expressed in all placenta: 3224.6 SPATA2 KIAA0757, PD1, PPP1R145, tamo ENSG00000158480 Spermatogenesis associated 2 20 49903391-49915508 Predicted intracellular proteins Evidence at protein level HPA048581, HPA052224 Uncertain Approved Nucleus
Nucleoli fibrillar center Endometrial cancer:1.87e-4 (unfavourable), Thyroid cancer:4.53e-4 (unfavourable), Melanoma:9.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.4 SPATA20 FLJ21347, SSP411, Tisp78 ENSG00000006282 Spermatogenesis associated 20 17 50543058-50555852 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA022023, HPA027144, HPA031442 Approved Approved Nucleoplasm Urothelial cancer:9.69e-5 (favourable) Expressed in all Expressed in all testis: 97.7 SPATA7 HSD3, LCA3 ENSG00000042317 Spermatogenesis associated 7 14 88384924-88470350 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA038082, HPA038083 Supported Approved Nucleoplasm
Mitochondria
Cytosol Renal cancer:2.50e-5 (favourable), Pancreatic cancer:4.16e-5 (favourable) Expressed in all Expressed in all testis: 102.2 SPATS2 FLJ13117, SCR59, SPATA10 ENSG00000123352 Spermatogenesis associated, serine-rich 2 12 49366584-49527424 Predicted intracellular proteins Evidence at protein level HPA038642, HPA038643, HPA066105 Uncertain Validated Cytosol Liver cancer:9.57e-8 (unfavourable), Ovarian cancer:1.44e-4 (favourable), Renal cancer:5.20e-4 (unfavourable) Expressed in all Expressed in all testis: 49.5 SPATS2L DNAPTP6 ENSG00000196141 Spermatogenesis associated, serine-rich 2-like 2 200305881-200482263 Predicted intracellular proteins Evidence at protein level HPA055427, HPA066310 Uncertain Validated Nucleoli
Cytosol Pancreatic cancer:7.43e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 168.1 SPCS1 HSPC033, SPC1, SPC12, YJR010C-A ENSG00000114902 Signal peptidase complex subunit 1 3 52704955-52711146 Predicted membrane proteins Evidence at protein level HPA046091, HPA055273 Supported Approved Golgi apparatus
Vesicles Renal cancer:2.90e-4 (favourable), Colorectal cancer:9.28e-4 (favourable) Expressed in all Expressed in all testis: 215.4 SPCS2 KIAA0102 ENSG00000118363 Signal peptidase complex subunit 2 11 74949247-74979031 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013386 Approved Approved Nucleus Expressed in all Expressed in all epididymis: 264.2 SPCS3 FLJ22649, PRO3567, SPC22/23, SPC3, YLR066W ENSG00000129128 Signal peptidase complex subunit 3 4 176319964-176332245 Predicted intracellular proteins Evidence at protein level HPA053180 Approved Endometrial cancer:8.89e-6 (favourable), Pancreatic cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 103.8 SPECC1 CYTSB, FLJ36955, HCMOGT-1, NSP ENSG00000128487 Sperm antigen with calponin homology and coiled-coil domains 1 17 20009344-20319026 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021421, HPA021430 Approved Lung cancer:1.06e-5 (unfavourable) Expressed in all Expressed in all testis: 67.2 SPECC1L CYTSA, KIAA0376 ENSG00000100014 Sperm antigen with calponin homology and coiled-coil domains 1-like 22 24270817-24417740 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA070614 Uncertain Supported Actin filaments Pancreatic cancer:7.92e-4 (favourable) Expressed in all Expressed in all testis: 58.3 SPEN KIAA0929, MINT, RBM15C, SHARP ENSG00000065526 Spen family transcriptional repressor 1 15847864-15940460 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015825, HPA050257 Supported Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 38.3 SPG11 FLJ21439, KIAA1840 ENSG00000104133 Spastic paraplegia 11 (autosomal recessive) 15 44562696-44663678 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040412, HPA040947 Approved Supported Nucleoli
Plasma membrane
Cytosol Renal cancer:6.28e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 49.0 SPG20 KIAA0610, TAHCCP1 ENSG00000133104 Spastic paraplegia 20 (Troyer syndrome) 13 36301638-36370180 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039053, HPA039054, HPA061519 Approved Validated Plasma membrane
Cytosol Expressed in all Expressed in all epididymis: 80.0 SPG21 ACP33, BM-019, GL010, MAST ENSG00000090487 Spastic paraplegia 21 (autosomal recessive, Mast syndrome) 15 64963021-64990310 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040407, HPA040436 Approved Supported Vesicles
Cytosol Expressed in all Expressed in all epididymis: 179.9 SPG7 CAR, CMAR, SPG5C ENSG00000197912 Spastic paraplegia 7 (pure and complicated autosomal recessive) 16 89490917-89557768 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Endometrial cancer:2.22e-4 (favourable), Urothelial cancer:4.25e-4 (favourable), Pancreatic cancer:4.91e-4 (favourable) Expressed in all Expressed in all thyroid gland: 52.3 SPI1 OF, PU.1, SFPI1, SPI-1, SPI-A ENSG00000066336 Spi-1 proto-oncogene 11 47354860-47378576 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB004079, HPA044653 Supported Supported Nucleoplasm Renal cancer:2.07e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 212.9 SPIDR KIAA0146 ENSG00000164808 Scaffolding protein involved in DNA repair 8 47260575-47736306 Predicted intracellular proteins Evidence at protein level HPA027201, HPA041582 Approved Supported Nucleoplasm Renal cancer:2.04e-6 (unfavourable), Ovarian cancer:8.91e-4 (unfavourable) Expressed in all Expressed in all placenta: 32.4 SPIN1 SPIN, TDRD24 ENSG00000106723 Spindlin 1 9 88388419-88478694 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA000162, HPA068784 Uncertain Supported Nucleoplasm Renal cancer:8.69e-6 (favourable) Expressed in all Expressed in all endometrium: 101.1 SPIN2B SPIN-2, TDRD26 ENSG00000186787 Spindlin family, member 2B X 57118551-57121547 Predicted intracellular proteins Evidence at transcript level HPA000162, HPA069835 Uncertain Approved Nucleoplasm Renal cancer:1.78e-5 (favourable), Pancreatic cancer:3.39e-4 (favourable), Ovarian cancer:3.43e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 14.9 SPNS1 HSpin1, LAT, nrs, PP2030, SPIN1, SPINL ENSG00000169682 Spinster homolog 1 (Drosophila) 16 28974221-28984548 Predicted membrane proteins, Transporters Evidence at protein level HPA041995, HPA042988 Supported Approved Nucleoli fibrillar center
Golgi apparatus
Vesicles
Cytosol Mixed Expressed in all parathyroid gland: 36.3 SPOP BTBD32, TEF2 ENSG00000121067 Speckle-type POZ protein 17 49598884-49678234 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Liver cancer:6.88e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 120.3 SPOPL BTBD33 ENSG00000144228 Speckle-type POZ protein-like 2 138501801-138573547 Predicted intracellular proteins Evidence at protein level HPA034687 Uncertain Approved Vesicles Renal cancer:3.63e-4 (favourable) Expressed in all Expressed in all breast: 16.0 SPPL2A IMP3, PSL2 ENSG00000138600 Signal peptide peptidase like 2A 15 50702266-50765808 Enzymes, Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036062, HPA067304 Supported Supported Vesicles Expressed in all Expressed in all parathyroid gland: 285.5 SPPL2B IMP4, KIAA1532, PSL1 ENSG00000005206 Signal peptide peptidase like 2B 19 2328615-2354806 Enzymes, Predicted membrane proteins Evidence at protein level HPA039292 Approved Nucleoplasm
Plasma membrane
Centrosome Endometrial cancer:5.00e-5 (favourable), Pancreatic cancer:1.33e-4 (favourable), Renal cancer:6.45e-4 (unfavourable) Expressed in all Expressed in all testis: 49.2 SPPL3 DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4 ENSG00000157837 Signal peptide peptidase like 3 12 120762510-120904371 Enzymes, Predicted membrane proteins Evidence at protein level HPA004194, HPA059958 Uncertain Supported Vesicles
Plasma membrane Liver cancer:1.29e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 82.3 SPRED2 FLJ21897, FLJ31917, Spred-2 ENSG00000198369 Sprouty-related, EVH1 domain containing 2 2 65310851-65432637 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038256 Uncertain Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 44.1 SPRY1 hSPRY1 ENSG00000164056 Sprouty RTK signaling antagonist 1 4 123396795-123403760 Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB013538, HPA051369, HPA070554 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Expressed in all Expressed in all gallbladder: 132.5 SPRY2 hSPRY2 ENSG00000136158 Sprouty RTK signaling antagonist 2 13 80335976-80340951 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB037205, HPA042198 Approved Supported Microtubules Expressed in all Expressed in all adipose tissue: 69.8 SPRYD3 FLJ14800 ENSG00000167778 SPRY domain containing 3 12 53064316-53079420 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039426, HPA039685 Supported Approved Nucleoplasm
Actin filaments
Cytosol Renal cancer:1.78e-15 (favourable), Head and neck cancer:9.46e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 145.4 SPRYD4 DKFZp686N0877 ENSG00000176422 SPRY domain containing 4 12 56468567-56479707 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053469 Approved Approved Nucleoplasm Endometrial cancer:8.85e-5 (unfavourable), Lung cancer:4.52e-4 (favourable) Expressed in all Expressed in all liver: 35.4 SPRYD7 C13orf1, CLLD6 ENSG00000123178 SPRY domain containing 7 13 49912706-49936490 Predicted intracellular proteins Evidence at protein level HPA043934 Approved Approved Vesicles Cervical cancer:8.48e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 18.8 SPSB2 GRCC9, SSB-2 ENSG00000111671 SplA/ryanodine receptor domain and SOCS box containing 2 12 6870935-6889358 Predicted intracellular proteins Evidence at protein level HPA055225 Approved Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all lung: 12.8 SPSB3 C16orf31, SSB-3 ENSG00000162032 SplA/ryanodine receptor domain and SOCS box containing 3 16 1776712-1793700 Predicted intracellular proteins Evidence at protein level HPA046602 Approved Approved Mitochondria Mixed Expressed in all adrenal gland: 29.2 SPTAN1 ENSG00000197694 Spectrin, alpha, non-erythrocytic 1 9 128552558-128633662 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004581, HPA007927 Supported Approved Vesicles
Microtubules Renal cancer:1.84e-12 (favourable) Expressed in all Expressed in all cerebral cortex: 202.6 SPTBN1 ENSG00000115306 Spectrin, beta, non-erythrocytic 1 2 54456285-54671445 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012685, HPA013149 Supported Approved Golgi apparatus Renal cancer:2.59e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 369.9 SPTLC1 hLCB1, HSAN1, HSN1, LCB1, SPTI ENSG00000090054 Serine palmitoyltransferase, long chain base subunit 1 9 92031999-92115384 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA010860, CAB018747, HPA063907 Supported Supported Endoplasmic reticulum Renal cancer:1.36e-6 (favourable) Expressed in all Expressed in all thyroid gland: 108.0 SPTLC2 hLCB2a, KIAA0526, LCB2, LCB2A ENSG00000100596 Serine palmitoyltransferase, long chain base subunit 2 14 77505997-77616773 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA027552 Approved Mitochondria Renal cancer:6.69e-8 (favourable), Liver cancer:3.62e-4 (unfavourable) Expressed in all Expressed in all placenta: 29.0 SPTSSA C14orf147, ssSPTa ENSG00000165389 Serine palmitoyltransferase, small subunit A 14 34432789-34462356 Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all adrenal gland: 90.6 SPTY2D1 DKFZp686I068, FLJ39441, Spt2 ENSG00000179119 SPT2 chromatin protein domain containing 1 11 18606401-18634791 Predicted intracellular proteins Evidence at protein level HPA039372, HPA047957 Approved Approved Nucleus
Nucleoli Renal cancer:2.07e-4 (favourable), Pancreatic cancer:2.59e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 21.4 SQRDL CGI-44 ENSG00000137767 Sulfide quinone reductase-like (yeast) 15 45631148-45691294 Predicted intracellular proteins Evidence at protein level HPA017079, HPA041589 Supported Validated Mitochondria Endometrial cancer:2.57e-4 (favourable), Lung cancer:8.80e-4 (unfavourable) Expressed in all Expressed in all colon: 196.9 SQSTM1 A170, OSIL, p60, p62, p62B, PDB3 ENSG00000161011 Sequestosome 1 5 179806398-179838078 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004587, HPA064165 Approved Validated Vesicles
Cytosol Liver cancer:2.31e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 376.5 SRCAP DOMO1, EAF1, KIAA0309, SWR1 ENSG00000080603 Snf2-related CREBBP activator protein 16 30698209-30741409 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA028929 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 54.9 SRD5A3 FLJ13352, SRD5A2L, SRD5A2L1 ENSG00000128039 Steroid 5 alpha-reductase 3 4 55346109-55373096 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA027006 Uncertain Approved Plasma membrane
Cytosol Renal cancer:4.85e-10 (unfavourable), Liver cancer:1.80e-6 (unfavourable), Endometrial cancer:9.39e-4 (favourable) Expressed in all Expressed in all gallbladder: 28.3 SREBF1 bHLHd1, SREBP-1c, SREBP1 ENSG00000072310 Sterol regulatory element binding transcription factor 1 17 17810399-17837002 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level CAB005406, HPA043343, HPA043878 Uncertain Supported Golgi apparatus
Cytosol Endometrial cancer:2.66e-4 (favourable), Pancreatic cancer:9.05e-4 (favourable) Expressed in all Expressed in all adrenal gland: 92.9 SREBF2 bHLHd2, SREBP2 ENSG00000198911 Sterol regulatory element binding transcription factor 2 22 41833079-41907308 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA031962, HPA031963 Approved Supported Nucleoplasm
Vesicles
Mitochondria Renal cancer:1.37e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 118.8 SREK1IP1 FLJ36754, P18SRP, SFRS12IP1 ENSG00000153006 SREK1-interacting protein 1 5 64718144-64768685 Predicted intracellular proteins Evidence at protein level HPA045677, HPA062853 Approved Approved Nucleus
Nucleoli Liver cancer:9.03e-4 (unfavourable), Renal cancer:9.68e-4 (unfavourable) Expressed in all Expressed in all placenta: 15.6 SRF MCM1 ENSG00000112658 Serum response factor 6 43171299-43181507 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001819, CAB005416 Supported Supported Nucleus Renal cancer:2.01e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 69.3 SRGAP2 ARHGAP34, FNBP2, KIAA0456, SRGAP2A ENSG00000266028 SLIT-ROBO Rho GTPase activating protein 2 1 206203345-206464443 Predicted intracellular proteins Evidence at protein level HPA028191, HPA028196 Approved Supported Nucleoplasm
Cytosol Renal cancer:4.61e-7 (unfavourable), Liver cancer:9.61e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 54.3 SRI ENSG00000075142 Sorcin 7 88205118-88226993 Predicted intracellular proteins Evidence at protein level HPA019004, HPA073666 Supported Supported Nucleoplasm
Cytosol Lung cancer:3.08e-4 (favourable), Pancreatic cancer:9.03e-4 (unfavourable) Expressed in all Expressed in all colon: 572.6 SRM SPS1, SRML1 ENSG00000116649 Spermidine synthase 1 11054584-11060024 Enzymes, Predicted intracellular proteins Evidence at protein level HPA015746 Approved Approved Nucleoplasm
Cytosol Renal cancer:3.80e-8 (unfavourable), Liver cancer:2.25e-5 (unfavourable) Expressed in all Expressed in all appendix: 75.6 SRP14 ALURBP, MGC14326 ENSG00000140319 Signal recognition particle 14kDa (homologous Alu RNA binding protein) 15 40035739-40039188 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA053738, HPA065118 Approved Nucleus
Nucleoli Renal cancer:5.31e-4 (favourable) Expressed in all Expressed in all thyroid gland: 372.6 SRP19 ENSG00000153037 Signal recognition particle 19kDa 5 112861222-112869788 Predicted intracellular proteins, Transporters Evidence at protein level HPA029272 Approved Renal cancer:3.72e-10 (unfavourable) Expressed in all Expressed in all thyroid gland: 64.7 SRP54 ENSG00000100883 Signal recognition particle 54kDa 14 34981957-35029567 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA048977, HPA062044 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all testis: 89.5 SRP68 ENSG00000167881 Signal recognition particle 68kDa 17 76038775-76072653 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA023303, HPA055617 Approved Validated Focal adhesion sites
Cytosol Liver cancer:4.28e-5 (unfavourable), Head and neck cancer:2.18e-4 (unfavourable), Thyroid cancer:2.65e-4 (favourable) Expressed in all Expressed in all thyroid gland: 71.7 SRP72 ENSG00000174780 Signal recognition particle 72kDa 4 56466915-56503680 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA034621 Approved Liver cancer:3.25e-6 (unfavourable), Colorectal cancer:3.83e-4 (favourable) Expressed in all Expressed in all thyroid gland: 88.8 SRP9 ENSG00000143742 Signal recognition particle 9kDa 1 225777813-225790466 Predicted intracellular proteins, Transporters Evidence at protein level Expressed in all Expressed in all cerebral cortex: 341.1 SRPK1 SFRSK1 ENSG00000096063 SRSF protein kinase 1 6 35832966-35921342 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016431, HPA056486 Approved Supported Nucleus
Plasma membrane
Cytosol Liver cancer:7.90e-6 (unfavourable), Pancreatic cancer:6.53e-5 (unfavourable) Expressed in all Expressed in all testis: 81.8 SRPR Sralpha, SRP-alpha ENSG00000182934 Signal recognition particle receptor (docking protein) 11 126262919-126269144 Plasma proteins, Predicted intracellular proteins Evidence at protein level Endometrial cancer:8.56e-4 (favourable) Expressed in all Expressed in all epididymis: 167.7 SRPRB APMCF1 ENSG00000144867 Signal recognition particle receptor, B subunit 3 133784033-133825772 Predicted membrane proteins Evidence at protein level HPA011173 Approved Approved Plasma membrane Liver cancer:3.12e-5 (unfavourable) Expressed in all Expressed in all epididymis: 51.1 SRR ILV1, ISO1 ENSG00000167720 Serine racemase 17 2303383-2325260 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007529, CAB015343 Approved Approved Vesicles Renal cancer:2.45e-6 (favourable), Endometrial cancer:6.20e-5 (favourable), Pancreatic cancer:8.16e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 25.6 SRRD HC/HCC, SRR1L ENSG00000100104 SRR1 domain containing 22 26483877-26494658 Predicted intracellular proteins Evidence at protein level HPA002945 Uncertain Approved Cytosol Liver cancer:2.16e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 29.9 SRRM1 MGC39488, POP101, SRM160 ENSG00000133226 Serine/arginine repetitive matrix 1 1 24631716-24673267 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA049941, HPA058612 Supported Validated Nuclear speckles Liver cancer:1.08e-4 (unfavourable) Expressed in all Expressed in all epididymis: 96.3 SRRM2 Cwc21, KIAA0324, SRL300, SRm300 ENSG00000167978 Serine/arginine repetitive matrix 2 16 2752329-2772538 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041411, HPA066181 Supported Validated Nuclear speckles Renal cancer:4.82e-4 (unfavourable), Liver cancer:5.08e-4 (unfavourable), Head and neck cancer:6.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 283.6 SRRT ARS2, Asr2, serrate ENSG00000087087 Serrate, RNA effector molecule 7 100875111-100888664 Predicted intracellular proteins Evidence at protein level HPA042858, HPA058379 Supported Validated Nucleoplasm Renal cancer:1.01e-6 (unfavourable), Liver cancer:1.90e-5 (unfavourable) Expressed in all Expressed in all testis: 203.7 SRSF1 ASF, MGC5228, SF2, SF2p33, SFRS1, SRp30a ENSG00000136450 Serine/arginine-rich splicing factor 1 17 58003360-58007346 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013073, HPA061301 Supported Validated Nucleoplasm Liver cancer:1.64e-6 (unfavourable), Renal cancer:2.95e-5 (unfavourable), Colorectal cancer:4.56e-5 (favourable), Cervical cancer:7.00e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 153.4 SRSF10 FUSIP1, FUSIP2, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR1, TASR2 ENSG00000188529 Serine/arginine-rich splicing factor 10 1 23964804-23980927 Predicted intracellular proteins Evidence at protein level HPA053805, HPA053831 Uncertain Supported Nucleoplasm Liver cancer:1.18e-6 (unfavourable), Renal cancer:1.01e-5 (unfavourable), Prostate cancer:1.74e-4 (unfavourable) Expressed in all Expressed in all endometrium: 100.3 SRSF11 NET2, p54, SFRS11 ENSG00000116754 Serine/arginine-rich splicing factor 11 1 70205682-70253052 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008762 Supported Supported Nuclear speckles Renal cancer:6.53e-6 (unfavourable), Liver cancer:3.91e-4 (unfavourable) Expressed in all Expressed in all endometrium: 96.2 SRSF2 PR264, SC-35, SC35, SFRS2, SFRS2A ENSG00000161547 Serine/arginine-rich splicing factor 2 17 76734115-76737374 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA049905 Supported Approved Nucleus
Cytosol Liver cancer:3.53e-8 (unfavourable), Renal cancer:1.05e-7 (unfavourable), Endometrial cancer:8.73e-4 (unfavourable), Urothelial cancer:9.87e-4 (favourable) Expressed in all Expressed in all lymph node: 128.8 SRSF3 SFRS3, SRp20 ENSG00000112081 Serine/arginine-rich splicing factor 3 6 36594353-36605600 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012986, HPA056981 Supported Supported Nucleoplasm Liver cancer:6.22e-5 (unfavourable), Ovarian cancer:1.37e-4 (favourable), Melanoma:1.95e-4 (unfavourable), Renal cancer:2.02e-4 (unfavourable), Colorectal cancer:2.56e-4 (favourable) Expressed in all Expressed in all lymph node: 141.5 SRSF4 SFRS4, SRP75 ENSG00000116350 Serine/arginine-rich splicing factor 4 1 29147743-29181987 Predicted intracellular proteins Evidence at protein level HPA050975 Supported Supported Nuclear speckles Melanoma:3.27e-4 (unfavourable), Prostate cancer:4.26e-4 (unfavourable), Renal cancer:4.30e-4 (unfavourable) Expressed in all Expressed in all placenta: 78.8 SRSF5 HRS, SFRS5, SRP40 ENSG00000100650 Serine/arginine-rich splicing factor 5 14 69726900-69772005 Predicted intracellular proteins Evidence at protein level HPA043484, HPA056523 Approved Validated Nucleus
Nucleoli Cervical cancer:7.91e-4 (favourable) Expressed in all Expressed in all fallopian tube: 313.9 SRSF6 B52, SFRS6, SRP55 ENSG00000124193 Serine/arginine-rich splicing factor 6 20 43457928-43464247 Predicted intracellular proteins Evidence at protein level HPA029005, CAB034889 Supported Supported Nuclear speckles Renal cancer:2.82e-4 (unfavourable), Liver cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all endometrium: 82.9 SRSF7 9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2 ENSG00000115875 Serine/arginine-rich splicing factor 7 2 38743599-38751494 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043850, HPA056926 Supported Validated Nucleoplasm Renal cancer:3.18e-8 (unfavourable), Liver cancer:2.90e-5 (unfavourable) Expressed in all Expressed in all testis: 99.3 SRSF8 SFRS2B, SRP46 ENSG00000263465 Serine/arginine-rich splicing factor 8 11 95067197-95071224 Predicted intracellular proteins Evidence at protein level HPA049905 Supported Supported Nucleus
Cytosol Renal cancer:9.99e-7 (favourable) Expressed in all Expressed in all thyroid gland: 44.5 SRSF9 SFRS9, SRp30c ENSG00000111786 Serine/arginine-rich splicing factor 9 12 120461668-120469793 Predicted intracellular proteins Evidence at protein level HPA049849 Supported Approved Nucleoplasm Liver cancer:9.85e-7 (unfavourable), Melanoma:7.80e-4 (unfavourable) Expressed in all Expressed in all testis: 138.5 SRXN1 C20orf139, dJ850E9.2, Npn3, SRX1, YKL086W ENSG00000271303 Sulfiredoxin 1 20 646615-653370 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:6.22e-5 (unfavourable) Mixed Expressed in all adrenal gland: 44.7 SS18 SSXT, SYT ENSG00000141380 Synovial sarcoma translocation, chromosome 18 18 26016253-26091217 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA055741, HPA059539 Supported Approved Nucleoplasm
Cytosol Renal cancer:4.86e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 74.4 SS18L1 KIAA0693 ENSG00000184402 Synovial sarcoma translocation gene on chromosome 18-like 1 20 62143795-62182484 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB011827, HPA059046 Approved Supported Nucleoplasm
Cytosol Head and neck cancer:8.00e-5 (favourable), Lung cancer:3.74e-4 (favourable) Expressed in all Expressed in all skin: 23.7 SS18L2 KIAA-iso ENSG00000008324 Synovial sarcoma translocation gene on chromosome 18-like 2 3 42581840-42595114 Predicted intracellular proteins Evidence at protein level HPA047377 Uncertain Approved Nucleus
Nucleoli
Mitochondria Lung cancer:7.03e-4 (favourable) Expressed in all Expressed in all lymph node: 58.8 SSB La, La/SSB, LARP3 ENSG00000138385 Sjogren syndrome antigen B (autoantigen La) 2 169791933-169812064 Predicted intracellular proteins Evidence at protein level CAB004643, HPA017287 Supported Approved Nucleoplasm Liver cancer:8.30e-8 (unfavourable), Renal cancer:6.17e-6 (unfavourable), Head and neck cancer:5.99e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 130.8 SSBP1 mtSSB, SSBP ENSG00000106028 Single-stranded DNA binding protein 1, mitochondrial 7 141738321-141787922 Predicted intracellular proteins Evidence at protein level HPA002866 Supported Supported Mitochondria Ovarian cancer:3.40e-4 (favourable), Liver cancer:4.42e-4 (unfavourable) Expressed in all Expressed in all testis: 147.1 SSBP2 HSPC116 ENSG00000145687 Single-stranded DNA binding protein 2 5 81413021-81751797 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB020834 Approved Approved Nucleoplasm Mixed Expressed in all parathyroid gland: 84.2 SSBP3 CSDP, FLJ10355, SSDP, SSDP1 ENSG00000157216 Single stranded DNA binding protein 3 1 54225432-54413479 Predicted intracellular proteins Evidence at protein level Cervical cancer:2.48e-9 (favourable), Endometrial cancer:2.10e-4 (unfavourable) Expressed in all Expressed in all ovary: 117.3 SSBP4 ENSG00000130511 Single stranded DNA binding protein 4 19 18418864-18434562 Predicted intracellular proteins Evidence at protein level Renal cancer:2.04e-10 (unfavourable), Pancreatic cancer:1.01e-4 (favourable) Expressed in all Expressed in all spleen: 52.1 SSFA2 CS-1, KIAA1927, KRAP, SPAG13 ENSG00000138434 Sperm specific antigen 2 2 181891833-181930738 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034665, HPA039989 Uncertain Supported Nucleus
Plasma membrane
Cytosol Renal cancer:2.91e-5 (favourable), Urothelial cancer:5.79e-5 (unfavourable), Pancreatic cancer:8.19e-4 (unfavourable) Expressed in all Expressed in all skin: 137.4 SSH2 KIAA1725 ENSG00000141298 Slingshot protein phosphatase 2 17 29625938-29930276 Enzymes, Predicted intracellular proteins Evidence at protein level CAB017189, HPA057099 Approved Expressed in all Expressed in all bone marrow: 35.8 SSH3 FLJ10928, FLJ20515 ENSG00000172830 Slingshot protein phosphatase 3 11 67303448-67312607 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019949, HPA019957 Approved Approved Nuclear speckles
Plasma membrane
Actin filaments
Cytosol Pancreatic cancer:2.89e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 37.1 SSNA1 N14, NA14 ENSG00000176101 Sjogren syndrome nuclear autoantigen 1 9 137188647-137190370 Predicted intracellular proteins Evidence at protein level Endometrial cancer:8.94e-4 (favourable) Expressed in all Expressed in all testis: 101.3 SSR1 TRAPA ENSG00000124783 Signal sequence receptor, alpha 6 7268306-7347446 Predicted membrane proteins Evidence at protein level HPA011276, HPA017062 Supported Supported Endoplasmic reticulum Renal cancer:5.79e-6 (unfavourable), Liver cancer:4.92e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 140.5 SSR2 TLAP, TRAPB ENSG00000163479 Signal sequence receptor, beta (translocon-associated protein beta) 1 156009048-156020959 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.00e-7 (unfavourable), Liver cancer:2.86e-4 (unfavourable) Expressed in all Expressed in all epididymis: 541.4 SSR3 TRAPG ENSG00000114850 Signal sequence receptor, gamma (translocon-associated protein gamma) 3 156540140-156555184 Predicted membrane proteins Evidence at protein level HPA014906 Approved Approved Uncertain Cytosol Liver cancer:4.46e-7 (unfavourable), Renal cancer:2.84e-4 (unfavourable), Head and neck cancer:3.43e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 203.5 SSR4 TRAPD ENSG00000180879 Signal sequence receptor, delta X 153793516-153798505 Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA045209 Supported Renal cancer:5.51e-6 (unfavourable), Endometrial cancer:1.76e-4 (favourable) Expressed in all Expressed in all epididymis: 962.9 SSRP1 FACT80 ENSG00000149136 Structure specific recognition protein 1 11 57325985-57335877 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002697 Approved Approved Nucleus
Cytosol Liver cancer:4.03e-7 (unfavourable), Pancreatic cancer:1.40e-4 (unfavourable), Renal cancer:5.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 122.9 SSSCA1 p27 ENSG00000173465 Sjogren syndrome/scleroderma autoantigen 1 11 65570430-65573942 Predicted intracellular proteins Evidence at protein level HPA039789 Uncertain Approved Cytosol Expressed in all Expressed in all cerebral cortex: 52.8 SSU72 HSPC182 ENSG00000160075 SSU72 homolog, RNA polymerase II CTD phosphatase 1 1541673-1574869 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069290, HPA070604 Supported Approved Nucleoplasm
Cytosol Expressed in all Expressed in all thyroid gland: 148.9 ST13 FAM10A1, HIP, HSPABP1, P48, SNC6 ENSG00000100380 Suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 22 40824535-40857022 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043233, HPA046412, HPA047114, HPA047116 Supported Validated Cytosol Renal cancer:3.10e-4 (favourable), Head and neck cancer:5.23e-4 (unfavourable) Expressed in all Expressed in all ovary: 778.9 ST3GAL1 SIAT4A, SIATFL, ST3GalA.1, ST3O ENSG00000008513 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 8 133454848-133571940 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA040466 Approved Expressed in all Expressed in all thyroid gland: 115.4 ST3GAL3 MRT12, SIAT6 ENSG00000126091 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 1 43705824-43931165 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051102 Uncertain Expressed in all Expressed in all skeletal muscle: 30.5 ST5 DENND2B, HTS1, p126 ENSG00000166444 Suppression of tumorigenicity 5 11 8693351-8910951 Predicted intracellular proteins Evidence at protein level HPA046796 Approved Approved Nucleoplasm Expressed in all Expressed in all endometrium: 190.3 ST6GAL1 SIAT1 ENSG00000073849 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 3 186930485-187078553 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB015018, CAB016122 Supported Expressed in all Expressed in all liver: 271.6 ST6GALNAC2 SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM ENSG00000070731 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 17 76563710-76586956 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048849 Uncertain Pancreatic cancer:6.48e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 77.3 ST6GALNAC6 SIAT7F, ST6GALNACVI ENSG00000160408 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 9 127885321-127905408 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018890 Approved Approved Nucleus Expressed in all Expressed in all rectum: 156.5 ST7 ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7 ENSG00000004866 Suppression of tumorigenicity 7 7 116953238-117230103 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038325, HPA038326 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.39e-5 (favourable) Expressed in all Expressed in all thyroid gland: 50.9 STAB1 CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, STAB-1 ENSG00000010327 Stabilin 1 3 52495338-52524495 Predicted membrane proteins Evidence at protein level HPA005434 Approved Renal cancer:3.88e-7 (unfavourable), Colorectal cancer:7.59e-4 (unfavourable) Expressed in all Expressed in all spleen: 125.2 STAG1 SA-1, SA1, SCC3A ENSG00000118007 Stromal antigen 1 3 136336233-136752403 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035015, HPA058653 Supported Validated Nucleus
Nuclear bodies Expressed in all Expressed in all endometrium: 31.7 STAG2 SA-2, SA2, SCC3B ENSG00000101972 Stromal antigen 2 X 123960212-124422664 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002857 Supported Expressed in all Expressed in all parathyroid gland: 110.6 STAM STAM1 ENSG00000136738 Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 10 17644125-17715914 Predicted intracellular proteins Evidence at protein level CAB034399, HPA043882 Supported Supported Vesicles Liver cancer:3.44e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 41.9 STAM2 Hbp ENSG00000115145 Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 2 152116801-152175992 Predicted intracellular proteins Evidence at protein level HPA035528, HPA035529 Supported Supported Nucleoplasm
Vesicles
Cytosol Expressed in all Expressed in all thyroid gland: 22.7 STAMBP AMSH ENSG00000124356 STAM binding protein 2 73828916-73873659 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA035800 Uncertain Supported Nucleoplasm
Plasma membrane
Cytosol Endometrial cancer:4.70e-5 (unfavourable), Pancreatic cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 39.2 STARD10 CGI-52, NY-CO-28, PCTP2, SDCCAG28 ENSG00000214530 StAR-related lipid transfer (START) domain containing 10 11 72754729-72794168 Predicted intracellular proteins Evidence at protein level HPA026661 Uncertain Breast cancer:6.92e-4 (favourable) Expressed in all Expressed in all rectum: 209.4 STARD3 es64, MLN64 ENSG00000131748 StAR-related lipid transfer (START) domain containing 3 17 39637065-39663484 Cancer-related genes, Predicted membrane proteins, Transporters Evidence at protein level CAB017021 Uncertain Liver cancer:3.60e-5 (unfavourable), Renal cancer:7.70e-4 (unfavourable) Expressed in all Expressed in all testis: 33.3 STARD3NL MENTHO, MGC3251 ENSG00000010270 STARD3 N-terminal like 7 38178222-38230671 Predicted membrane proteins Evidence at protein level HPA019204 Supported Supported Vesicles Liver cancer:1.44e-5 (unfavourable), Head and neck cancer:2.20e-4 (unfavourable), Pancreatic cancer:8.48e-4 (favourable) Expressed in all Expressed in all placenta: 69.9 STARD7 GTT1 ENSG00000084090 StAR-related lipid transfer (START) domain containing 7 2 96184859-96208825 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB033965, HPA064958, HPA064978 Supported Approved Mitochondria Renal cancer:4.38e-6 (favourable), Glioma:5.94e-6 (favourable), Endometrial cancer:8.56e-5 (unfavourable), Liver cancer:2.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 106.6 STAT1 ISGF-3, STAT91 ENSG00000115415 Signal transducer and activator of transcription 1, 91kDa 2 190964358-191020960 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000931, HPA000982, CAB004049 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.22e-5 (unfavourable), Ovarian cancer:1.75e-4 (favourable), Pancreatic cancer:4.23e-4 (unfavourable) Expressed in all Expressed in all lymph node: 196.3 STAT2 STAT113 ENSG00000170581 Signal transducer and activator of transcription 2, 113kDa 12 56341597-56360155 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003858, HPA018888 Approved Supported Plasma membrane
Cytosol Renal cancer:4.78e-13 (unfavourable), Endometrial cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all spleen: 48.7 STAT3 APRF ENSG00000168610 Signal transducer and activator of transcription 3 (acute-phase response factor) 17 42313324-42388568 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001671, CAB003859, HPA058603, CAB068241, CAB068242 Supported Supported Nucleoplasm
Cytosol Expressed in all Expressed in all gallbladder: 127.9 STAT5A MGF, STAT5 ENSG00000126561 Signal transducer and activator of transcription 5A 17 42287547-42311943 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB003860, HPA027873, HPA042128, HPA049883, HPA051156 Approved Validated Nucleoplasm
Cytosol Breast cancer:5.87e-4 (favourable) Expressed in all Expressed in all adipose tissue: 90.2 STAT5B ENSG00000173757 Signal transducer and activator of transcription 5B 17 42199168-42276707 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004298, HPA042128, HPA049883, HPA051156 Approved Renal cancer:2.39e-5 (favourable), Pancreatic cancer:1.63e-4 (favourable), Endometrial cancer:9.37e-4 (favourable) Expressed in all Expressed in all endometrium: 70.8 STAT6 D12S1644, IL-4-STAT ENSG00000166888 Signal transducer and activator of transcription 6, interleukin-4 induced 12 57095408-57132139 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001861 Approved Validated Nucleoplasm
Cytosol Urothelial cancer:1.14e-4 (favourable), Endometrial cancer:1.69e-4 (favourable), Thyroid cancer:7.76e-4 (favourable) Expressed in all Expressed in all skin: 164.0 STAU1 PPP1R150, STAU ENSG00000124214 Staufen double-stranded RNA binding protein 1 20 49113339-49188367 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB020839, HPA049892 Approved Supported Cytosol Prostate cancer:4.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 138.2 STAU2 39K2 ENSG00000040341 Staufen double-stranded RNA binding protein 2 8 73420369-73747708 Predicted intracellular proteins Evidence at protein level HPA019155, CAB020836 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 74.3 STEAP4 FLJ23153, STAMP2, TIARP, TNFAIP9 ENSG00000127954 STEAP family member 4 7 88270892-88306891 Predicted membrane proteins, Transporters Evidence at protein level HPA075871 Supported Golgi apparatus Liver cancer:2.97e-4 (favourable), Stomach cancer:5.77e-4 (unfavourable) Tissue enhanced Expressed in all adipose tissue: 129.9 STIM1 D11S4896E, GOK ENSG00000167323 Stromal interaction molecule 1 11 3854527-4093210 Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA011088, HPA012123, CAB037128, CAB037288 Supported Validated Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 86.3 STIM2 ENSG00000109689 Stromal interaction molecule 2 4 26857678-27025381 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA036933, CAB037196, HPA057511 Supported Approved Vesicles Liver cancer:3.97e-5 (unfavourable), Pancreatic cancer:5.01e-4 (favourable) Expressed in all Expressed in all gallbladder: 44.5 STIP1 HOP, STI1 ENSG00000168439 Stress-induced phosphoprotein 1 11 64185272-64204543 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017448, HPA039291, HPA044062 Supported Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:6.18e-8 (unfavourable), Head and neck cancer:1.23e-4 (unfavourable) Expressed in all Expressed in all testis: 219.7 STK10 LOK, PRO2729 ENSG00000072786 Serine/threonine kinase 10 5 172042073-172188386 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA015083, CAB020840 Supported Renal cancer:1.63e-4 (unfavourable), Colorectal cancer:2.76e-4 (favourable) Expressed in all Expressed in all spleen: 62.1 STK11 LKB1, PJS ENSG00000118046 Serine/threonine kinase 11 19 1177558-1228435 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB016231, HPA017254, CAB022105, HPA067481 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:3.69e-5 (favourable), Head and neck cancer:1.96e-4 (favourable) Expressed in all Expressed in all testis: 70.3 STK11IP KIAA1898, LIP1, LKB1IP, STK11IP1 ENSG00000144589 Serine/threonine kinase 11 interacting protein 2 219597860-219616451 Predicted intracellular proteins Evidence at protein level HPA036837, HPA036838, HPA053192 Approved Validated Vesicles Pancreatic cancer:1.63e-4 (favourable) Expressed in all Expressed in all testis: 39.7 STK16 MPSK, PKL12 ENSG00000115661 Serine/threonine kinase 16 2 219245455-219250337 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029450 Approved Approved Cytosol Endometrial cancer:6.09e-4 (favourable) Expressed in all Expressed in all testis,thyroid gland: 28.6 STK17A DRAK1 ENSG00000164543 Serine/threonine kinase 17a 7 43582758-43626786 Enzymes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA018138, HPA037979 Uncertain Approved Nuclear speckles
Plasma membrane Expressed in all Expressed in all lymph node: 49.9 STK24 MST-3, MST3, MST3B, STE20, STK3 ENSG00000102572 Serine/threonine kinase 24 13 98445185-98577940 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026435, HPA026502 Supported Supported Nucleoli
Cytosol Lung cancer:6.23e-6 (unfavourable), Renal cancer:6.91e-5 (favourable), Pancreatic cancer:5.81e-4 (unfavourable) Expressed in all Expressed in all esophagus: 170.1 STK25 SOK1, YSK1 ENSG00000115694 Serine/threonine kinase 25 2 241492674-241509730 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047147 Uncertain Liver cancer:3.91e-8 (unfavourable), Colorectal cancer:6.03e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 168.2 STK3 KRS1, MST2 ENSG00000104375 Serine/threonine kinase 3 8 98401403-98942827 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007120, CAB025316 Uncertain Approved Intermediate filaments
Cytosol
Rods & Rings Pancreatic cancer:9.21e-5 (unfavourable), Endometrial cancer:1.53e-4 (unfavourable), Lung cancer:4.25e-4 (unfavourable) Expressed in all Expressed in all endometrium: 48.3 STK32C MGC23665, PKE, YANK3 ENSG00000165752 Serine/threonine kinase 32C 10 132207492-132331847 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017894 Uncertain Liver cancer:1.68e-6 (unfavourable), Renal cancer:5.31e-6 (unfavourable), Endometrial cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all testis: 52.8 STK35 bA550O8.2, CLIK1 ENSG00000125834 Serine/threonine kinase 35 20 2101611-2177038 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026452, HPA051673 Uncertain Supported Nucleus
Nuclear bodies Liver cancer:9.46e-6 (unfavourable) Expressed in all Expressed in all testis: 25.2 STK36 FU, KIAA1278 ENSG00000163482 Serine/threonine kinase 36 2 218672026-218702716 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027409, HPA027453, HPA030058 Approved Supported Cytosol Liver cancer:5.20e-4 (unfavourable) Expressed in all Expressed in all testis: 58.8 STK38 NDR ENSG00000112079 Serine/threonine kinase 38 6 36493892-36547470 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004673, HPA038623, HPA051324 Uncertain Approved Cytosol Melanoma:9.44e-5 (unfavourable) Expressed in all Expressed in all rectum: 40.9 STK38L KIAA0965, NDR2 ENSG00000211455 Serine/threonine kinase 38 like 12 27243968-27325959 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038623, HPA051324 Approved Approved Cytosol Pancreatic cancer:5.82e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 64.3 STK4 KRS2, MST1, YSK3 ENSG00000101109 Serine/threonine kinase 4 20 44966474-45079959 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level CAB004038, HPA015270 Approved Validated Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.84e-5 (unfavourable), Liver cancer:8.04e-4 (unfavourable) Expressed in all Expressed in all lymph node: 51.4 STK40 MGC4796, SgK495 ENSG00000196182 Serine/threonine kinase 40 1 36339624-36385896 Enzymes, Predicted membrane proteins Evidence at protein level HPA008026 Uncertain Supported Nucleoplasm
Cytosol Pancreatic cancer:5.59e-4 (favourable) Expressed in all Expressed in all testis: 57.0 STMN1 C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN ENSG00000117632 Stathmin 1 1 25884181-25906991 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB010107 Approved Supported Cytosol Liver cancer:9.90e-7 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1042.5 STOM BND7, EPB7, EPB72 ENSG00000148175 Stomatin 9 121338988-121370304 Plasma proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA010961, HPA011419 Approved Validated Cytosol Expressed in all Expressed in all adipose tissue: 461.2 STOML1 FLJ36370, hUNC-24, SLP-1, STORP ENSG00000067221 Stomatin (EPB72)-like 1 15 73978923-73994622 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042353 Approved Approved Cytosol Expressed in all Expressed in all cerebral cortex: 43.8 STOML2 HSPC108, SLP-2 ENSG00000165283 Stomatin (EPB72)-like 2 9 35099776-35103195 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB015944, HPA062016 Approved Supported Plasma membrane
Cytosol Renal cancer:3.00e-5 (favourable), Liver cancer:4.77e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 97.5 STRA13 FAAP10, MGC14480, MHF2 ENSG00000169689 Stimulated by retinoic acid 13 17 82018702-82024107 Predicted intracellular proteins Evidence at protein level Renal cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all prostate: 67.4 STRADA LYK5, NY-BR-96, Stlk, STRAD ENSG00000266173 STE20-related kinase adaptor alpha 17 63702832-63741970 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA031637 Approved Supported Nucleoplasm
Cytosol Renal cancer:6.08e-7 (unfavourable), Pancreatic cancer:5.34e-5 (favourable), Urothelial cancer:6.43e-4 (favourable) Expressed in all Expressed in all testis: 68.8 STRADB ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK ENSG00000082146 STE20-related kinase adaptor beta 2 201387858-201480846 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026549, HPA028520 Approved Supported Aggresome
Cytosol Renal cancer:1.35e-4 (unfavourable), Thyroid cancer:4.45e-4 (favourable) Expressed in all Expressed in all kidney: 72.8 STRAP MAWD, pt-wd, UNRIP ENSG00000023734 Serine/threonine kinase receptor associated protein 12 15882391-15903478 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027320, HPA055557, HPA073876 Approved Validated Nucleoplasm
Cytosol Liver cancer:6.83e-6 (unfavourable), Urothelial cancer:5.10e-4 (unfavourable), Thyroid cancer:9.07e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 144.6 STRBP FLJ11307, ILF3L, SPNR ENSG00000165209 Spermatid perinuclear RNA binding protein 9 123109500-123268576 Predicted intracellular proteins Evidence at protein level HPA020651 Approved Renal cancer:1.70e-10 (favourable), Liver cancer:8.18e-4 (unfavourable) Expressed in all Expressed in all testis: 78.6 STRIP1 FAM40A, FAR11A, FLJ14743, KIAA1761 ENSG00000143093 Striatin interacting protein 1 1 110031577-110074641 Predicted intracellular proteins Evidence at protein level HPA060302, HPA060498 Approved Supported Cytosol Expressed in all Expressed in all parathyroid gland: 34.1 STRN SG2NA ENSG00000115808 Striatin, calmodulin binding protein 2 36843640-36966472 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA017286 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.27e-4 (favourable) Expressed in all Expressed in all esophagus: 23.9 STRN3 SG2NA ENSG00000196792 Striatin, calmodulin binding protein 3 14 30893799-31026401 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003392, HPA004636, CAB069925 Approved Supported Nucleoplasm
Actin filaments
Cytosol Renal cancer:9.66e-4 (favourable) Expressed in all Expressed in all testis: 44.4 STRN4 ZIN, zinedin ENSG00000090372 Striatin, calmodulin binding protein 4 19 46719507-46746994 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043051, HPA043527, HPA056706 Supported Approved Cytosol Liver cancer:6.06e-8 (unfavourable), Ovarian cancer:2.98e-4 (unfavourable) Expressed in all Expressed in all testis: 105.0 STT3B FLJ90106, SIMP, STT3-B ENSG00000163527 STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 3 31532638-31637622 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA036448, HPA036646 Approved Supported Endoplasmic reticulum Colorectal cancer:7.91e-5 (favourable) Expressed in all Expressed in all testis: 164.6 STUB1 CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1 ENSG00000103266 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 16 680224-682870 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB037202, CAB037209, HPA041222, HPA043531 Approved Supported Nucleoplasm
Cytosol Renal cancer:6.49e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 138.1 STX10 hsyn10, SYN10 ENSG00000104915 Syntaxin 10 19 13144058-13150383 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035303, HPA056439 Approved Approved Golgi apparatus Renal cancer:1.69e-7 (unfavourable), Lung cancer:8.26e-4 (favourable) Expressed in all Expressed in all skin: 57.0 STX12 STX13, STX14 ENSG00000117758 Syntaxin 12 1 27773183-27824452 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041038, HPA055300 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Expressed in all thyroid gland: 155.4 STX16 hsyn16, SYN16 ENSG00000124222 Syntaxin 16 20 58651253-58679526 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041019, HPA042033 Uncertain Validated Vesicles Renal cancer:1.11e-16 (unfavourable), Liver cancer:4.18e-4 (unfavourable) Expressed in all Expressed in all skin: 64.0 STX17 FLJ20651 ENSG00000136874 Syntaxin 17 9 99906633-99970341 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001204 Approved Uncertain Nucleoli
Cytosol Renal cancer:1.62e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 36.1 STX18 Ufe1 ENSG00000168818 Syntaxin 18 4 4415742-4542346 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003019 Approved Approved Plasma membrane Endometrial cancer:6.33e-8 (favourable), Colorectal cancer:2.84e-4 (favourable), Urothelial cancer:4.69e-4 (favourable), Renal cancer:7.03e-4 (favourable) Expressed in all Expressed in all cervix, uterine: 181.9 STX2 EPIM, EPM, STX2A, STX2B, STX2C ENSG00000111450 Syntaxin 2 12 130789600-130839266 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA038189, HPA069176 Uncertain Approved Nucleus
Cytosol Renal cancer:5.15e-5 (unfavourable) Expressed in all Expressed in all testis: 35.1 STX3 STX3A ENSG00000166900 Syntaxin 3 11 59713456-59805882 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA002191, HPA069176 Approved Supported Nucleus
Nuclear bodies
Cytosol Liver cancer:8.41e-7 (unfavourable), Renal cancer:1.14e-6 (favourable) Expressed in all Expressed in all placenta: 71.8 STX4 p35-2, STX4A ENSG00000103496 Syntaxin 4 16 31032889-31042975 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA001330 Approved Validated Plasma membrane Renal cancer:2.88e-9 (unfavourable), Cervical cancer:3.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 63.4 STX5 SED5, STX5A ENSG00000162236 Syntaxin 5 11 62806897-62832088 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001358 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all thyroid gland: 58.9 STX7 ENSG00000079950 Syntaxin 7 6 132445867-132513198 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001467, CAB062564 Supported Validated Lysosomes Liver cancer:1.60e-4 (unfavourable) Expressed in all Expressed in all lymph node: 92.5 STX8 CARB ENSG00000170310 Syntaxin 8 17 9250471-9576591 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001540 Approved Uncertain Nuclear bodies
Golgi apparatus
Actin filaments
Cytosol Expressed in all Expressed in all testis: 96.0 STXBP3 UNC-18C ENSG00000116266 Syntaxin binding protein 3 1 108746674-108809526 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027225 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 64.7 STYX ENSG00000198252 Serine/threonine/tyrosine interacting protein 14 52730180-52774998 Predicted intracellular proteins Evidence at protein level HPA040290 Uncertain Approved Nucleoplasm Expressed in all Expressed in all testis: 20.5 STYXL1 DUSP24, MK-STYX ENSG00000127952 Serine/threonine/tyrosine interacting-like 1 7 75996338-76048004 Predicted intracellular proteins Evidence at transcript level HPA050261 Uncertain Approved Nuclear speckles Urothelial cancer:8.22e-4 (favourable) Expressed in all Expressed in all fallopian tube: 45.5 SUB1 p14, p15, PC4 ENSG00000113387 SUB1 homolog, transcriptional regulator 5 32531633-32604079 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001311, CAB015351 Supported Supported Nucleus
Nucleoli Liver cancer:5.25e-6 (unfavourable), Melanoma:2.79e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 235.1 SUCLA2 ENSG00000136143 Succinate-CoA ligase, ADP-forming, beta subunit 13 47936491-48001354 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039435, HPA039536, HPA061528 Supported Supported Validated Mitochondria Renal cancer:7.59e-14 (favourable), Urothelial cancer:1.22e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 78.8 SUCLG1 ENSG00000163541 Succinate-CoA ligase, alpha subunit 2 84423523-84460045 Citric acid cycle related proteins, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins Evidence at protein level HPA036683, HPA036684 Supported Supported Plasma membrane
Mitochondria Renal cancer:2.21e-8 (favourable), Endometrial cancer:5.23e-4 (unfavourable) Expressed in all Expressed in all kidney: 467.4 SUCLG2 ENSG00000172340 Succinate-CoA ligase, GDP-forming, beta subunit 3 67360460-67654614 Citric acid cycle related proteins, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA046705, HPA051998 Supported Supported Plasma membrane
Mitochondria Renal cancer:2.79e-10 (favourable), Colorectal cancer:1.08e-4 (favourable) Expressed in all Expressed in all colon: 171.4 SUDS3 FLJ00052, SAP45, SDS3 ENSG00000111707 SDS3 homolog, SIN3A corepressor complex component 12 118376380-118418031 Predicted secreted proteins Evidence at protein level HPA040402, HPA041972 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all parathyroid gland: 35.6 SUGP2 KIAA0365, SFRS14 ENSG00000064607 SURP and G patch domain containing 2 19 18990888-19034023 Predicted intracellular proteins Evidence at protein level HPA041557, HPA061111 Supported Validated Nucleoplasm
Nuclear bodies Liver cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all testis: 161.3 SUGT1 SGT1 ENSG00000165416 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 13 52652709-52700909 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB015942, HPA043949 Uncertain Approved Nucleoplasm
Plasma membrane
Cytosol Head and neck cancer:8.69e-4 (unfavourable) Expressed in all Expressed in all testis: 63.2 SULF2 HSULF-2, KIAA1247, SULF-2 ENSG00000196562 Sulfatase 2 20 47656348-47786616 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA002325 Approved Cervical cancer:6.43e-5 (unfavourable), Renal cancer:4.02e-4 (unfavourable) Expressed in all Expressed in all endometrium: 166.1 SULT1A1 P-PST, STP, STP1 ENSG00000196502 Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 16 28605196-28623625 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049500, HPA051051 Supported Lung cancer:7.02e-4 (favourable) Expressed in all Expressed in all duodenum: 140.4 SULT1A3 STM, TL-PST ENSG00000261052 Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 16 30199228-30204310 Enzymes, Predicted intracellular proteins Evidence at protein level HPA049500, HPA051051 Supported Not detected Expressed in all duodenum: 109.2 SUMF1 FGE, UNQ3037 ENSG00000144455 Sulfatase modifying factor 1 3 3700814-4467281 Disease related genes, Predicted secreted proteins Evidence at protein level HPA038025 Uncertain Renal cancer:4.79e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 71.1 SUMF2 DKFZp566I1024 ENSG00000129103 Sulfatase modifying factor 2 7 56064002-56080670 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA024040, CAB025743, HPA074892 Supported Uncertain Vesicles
Plasma membrane Cervical cancer:6.58e-6 (unfavourable), Endometrial cancer:3.96e-4 (favourable), Urothelial cancer:7.71e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 159.3 SUMO1 GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1 ENSG00000116030 Small ubiquitin-like modifier 1 2 202206180-202238608 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004269, HPA056956 Supported Supported Nucleus
Nuclear membrane
Nucleoli
Nuclear bodies Ovarian cancer:7.93e-4 (favourable) Expressed in all Expressed in all thyroid gland: 170.7 SUMO2 SMT3B, SMT3H2 ENSG00000188612 Small ubiquitin-like modifier 2 17 75165586-75182983 Predicted intracellular proteins Evidence at protein level CAB037314, HPA042123, HPA048064 Supported Approved Nucleoplasm
Nuclear bodies Renal cancer:5.23e-6 (unfavourable), Endometrial cancer:1.88e-5 (unfavourable), Liver cancer:2.12e-4 (unfavourable) Expressed in all Expressed in all endometrium: 342.0 SUMO3 SMT3A, SMT3H1 ENSG00000184900 Small ubiquitin-like modifier 3 21 44805617-44818779 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012180, HPA042123, HPA048064 Supported Validated Nucleoplasm
Nuclear bodies Endometrial cancer:7.88e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 81.1 SUN1 FLJ12407, KIAA0810, UNC84A ENSG00000164828 Sad1 and UNC84 domain containing 1 7 816615-896435 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA008346, HPA008461 Supported Validated Nuclear membrane Expressed in all Expressed in all endometrium: 120.0 SUN2 UNC84B ENSG00000100242 Sad1 and UNC84 domain containing 2 22 38734725-38794143 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA001209 Supported Supported Nuclear membrane Expressed in all Expressed in all lymph node: 120.6 SUOX ENSG00000139531 Sulfite oxidase 12 55997180-56006641 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA038208, HPA038209 Approved Renal cancer:4.77e-7 (favourable), Urothelial cancer:8.32e-5 (favourable), Pancreatic cancer:6.28e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 106.1 SUPT16H CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68 ENSG00000092201 SPT16 homolog, facilitates chromatin remodeling subunit 14 21351472-21384266 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB022551, HPA049787 Supported Supported Nucleus
Nucleoli fibrillar center Expressed in all Expressed in all parathyroid gland: 94.3 SUPT20H bA421P11.4, C13orf19, FAM48A, P38IP, SPT20 ENSG00000102710 SPT20 homolog, SAGA complex component 13 37009312-37059713 Predicted intracellular proteins Evidence at protein level HPA038906, HPA038907 Uncertain Supported Nucleoli fibrillar center Expressed in all Expressed in all testis: 99.5 SUPT4H1 Spt4, SPT4H, Supt4a, SUPT4H ENSG00000213246 SPT4 homolog, DSIF elongation factor subunit 17 58345175-58353093 Predicted intracellular proteins Evidence at protein level HPA059748 Approved Nucleus Liver cancer:7.69e-5 (unfavourable) Expressed in all Expressed in all lymph node: 83.7 SUPT5H FLJ34157, SPT5, SPT5H ENSG00000196235 SPT5 homolog, DSIF elongation factor subunit 19 39436156-39476670 Predicted intracellular proteins Evidence at protein level HPA029273, CAB034370 Supported Validated Nucleoplasm Liver cancer:7.00e-5 (unfavourable) Expressed in all Expressed in all testis: 169.9 SUPT6H KIAA0162, SPT6H ENSG00000109111 SPT6 homolog, histone chaperone 17 28662091-28702684 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012416, HPA036382 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Liver cancer:3.68e-5 (unfavourable), Renal cancer:4.36e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 61.1 SUPT7L KIAA0764, SPT7L, STAF65, STAF65gamma ENSG00000119760 SPT7-like STAGA complex gamma subunit 2 27650812-27663840 Predicted intracellular proteins Evidence at protein level HPA039565, HPA063643 Uncertain Approved Nucleoplasm Liver cancer:4.46e-7 (unfavourable), Renal cancer:1.53e-4 (unfavourable), Endometrial cancer:2.28e-4 (unfavourable) Expressed in all Expressed in all endometrium: 45.3 SUPV3L1 SUV3 ENSG00000156502 SUV3-like helicase 10 69180232-69209099 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038380, HPA038405 Supported Supported Mitochondria Expressed in all Expressed in all testis: 28.9 SURF1 ENSG00000148290 Surfeit 1 9 133351755-133356676 Disease related genes, Predicted membrane proteins Evidence at protein level CAB033946 Uncertain Renal cancer:6.92e-9 (favourable) Expressed in all Expressed in all epididymis: 46.0 SURF2 ENSG00000148291 Surfeit 2 9 133356552-133361169 Predicted intracellular proteins Evidence at protein level HPA044340, HPA052213 Approved Validated Nucleus
Nucleoli Expressed in all Expressed in all testis: 39.1 SURF4 ERV29, FLJ22993, MGC102753 ENSG00000148248 Surfeit 4 9 133361449-133376166 Predicted membrane proteins Evidence at protein level HPA064613 Approved Head and neck cancer:1.47e-5 (unfavourable), Breast cancer:5.85e-4 (unfavourable), Liver cancer:8.11e-4 (unfavourable) Expressed in all Expressed in all small intestine: 84.4 SUSD6 KIAA0247 ENSG00000100647 Sushi domain containing 6 14 69611596-69715142 Predicted membrane proteins Evidence at protein level HPA030464 Uncertain Approved Nucleoplasm
Intermediate filaments Renal cancer:2.16e-4 (favourable) Expressed in all Expressed in all epididymis: 51.6 SUV420H1 CGI-85, KMT5B ENSG00000110066 Suppressor of variegation 4-20 homolog 1 (Drosophila) 11 68154863-68213828 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063648 Supported Nucleus Urothelial cancer:9.30e-4 (favourable) Expressed in all Expressed in all thyroid gland: 51.9 SUZ12 CHET9, JJAZ1, KIAA0160 ENSG00000178691 SUZ12 polycomb repressive complex 2 subunit 17 31937018-32001045 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA057436 Approved Approved Nucleus
Nucleoli
Nuclear bodies Expressed in all Expressed in all testis: 50.5 SVBP CCDC23, MGC45441 ENSG00000177868 Small vasohibin binding protein 1 42807052-42817252 Predicted intracellular proteins Evidence at protein level HPA008507 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Liver cancer:1.18e-4 (unfavourable), Breast cancer:6.33e-4 (favourable) Expressed in all Expressed in all testis: 82.8 SVIL ENSG00000197321 Supervillin 10 29457338-29736781 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010878, HPA020095, HPA020138 Approved Supported Plasma membrane
Actin filaments
Cytosol Urothelial cancer:5.70e-5 (unfavourable) Expressed in all Expressed in all skeletal muscle: 279.8 SVIP DKFZp313A2432 ENSG00000198168 Small VCP/p97-interacting protein 11 22813799-22830299 Predicted intracellular proteins Evidence at protein level HPA039807 Uncertain Renal cancer:1.77e-8 (favourable) Expressed in all Expressed in all thyroid gland: 39.0 SWAP70 KIAA0640, SWAP-70 ENSG00000133789 SWAP switching B-cell complex 70kDa subunit 11 9664077-9752991 Predicted intracellular proteins Evidence at protein level HPA006810 Supported Expressed in all Expressed in all spleen: 83.4 SWI5 bA395P17.9, C9orf119, SAE3 ENSG00000175854 SWI5 homologous recombination repair protein 9 128275379-128288990 Predicted intracellular proteins Evidence at protein level HPA052032, HPA055472 Approved Supported Nucleoplasm
Cytosol Liver cancer:6.78e-4 (unfavourable), Renal cancer:9.39e-4 (favourable) Expressed in all Expressed in all testis: 128.7 SYAP1 FLJ14495, PRO3113 ENSG00000169895 Synapse associated protein 1 X 16719632-16765336 Predicted secreted proteins Evidence at protein level HPA000175, HPA000882, HPA048047 Approved Validated Nucleoplasm
Golgi apparatus
Cytosol Ovarian cancer:3.18e-4 (favourable) Expressed in all Expressed in all adrenal gland: 33.7 SYF2 CBPIN, DKFZp564O2082, fSAP29, NTC31, p29 ENSG00000117614 SYF2 pre-mRNA-splicing factor 1 25222679-25232502 Predicted intracellular proteins Evidence at protein level HPA018265, HPA070710 Approved Supported Nuclear speckles Urothelial cancer:5.72e-4 (favourable) Expressed in all Expressed in all ovary: 136.1 SYMPK SPK, SYM ENSG00000125755 Symplekin 19 45815410-45863290 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041756, HPA042449 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Expressed in all Expressed in all testis: 74.6 SYNCRIP dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1 ENSG00000135316 Synaptotagmin binding, cytoplasmic RNA interacting protein 6 85607785-85643792 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010895, HPA041275 Supported Supported Nucleoplasm
Cytosol Liver cancer:6.28e-5 (unfavourable), Ovarian cancer:5.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 131.5 SYNE1 8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B ENSG00000131018 Spectrin repeat containing, nuclear envelope 1 6 152121684-152637801 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019113 Approved Supported Nucleoplasm
Nuclear membrane Mixed Expressed in all parathyroid gland: 58.0 SYNE2 DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2 ENSG00000054654 Spectrin repeat containing, nuclear envelope 2 14 63852983-64226433 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003435, HPA050204 Supported Validated Nuclear membrane Renal cancer:3.56e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 187.4 SYNGR1 ENSG00000100321 Synaptogyrin 1 22 39349925-39385588 Predicted membrane proteins Evidence at protein level HPA029673, CAB034277 Supported Supported Cytosol Renal cancer:4.98e-7 (favourable), Pancreatic cancer:2.41e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 175.9 SYNGR2 ENSG00000108639 Synaptogyrin 2 17 78168558-78173527 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014742 Approved Approved Golgi apparatus Renal cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all lung: 155.0 SYNJ2 INPP5H ENSG00000078269 Synaptojanin 2 6 157981887-158099176 Enzymes, Predicted intracellular proteins Evidence at protein level HPA031575 Approved Approved Microtubules
Cytosol Renal cancer:4.02e-6 (unfavourable), Breast cancer:2.63e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 35.6 SYNRG AP1GBP1, MGC104959, SYNG ENSG00000275066 Synergin, gamma 17 37514797-37609496 Predicted intracellular proteins Evidence at protein level HPA023554, HPA023555 Approved Approved Cytosol Urothelial cancer:3.96e-4 (favourable) Expressed in all Expressed in all testis: 20.3 SYPL1 SYPL ENSG00000008282 Synaptophysin-like 1 7 106090503-106112576 Predicted membrane proteins Evidence at protein level HPA014141 Approved Renal cancer:1.25e-9 (favourable) Expressed in all Expressed in all thyroid gland: 194.0 SYS1 C20orf169, dJ453C12.4 ENSG00000204070 Sys1 golgi trafficking protein 20 45361937-45376798 Predicted membrane proteins Evidence at protein level HPA046716 Approved Liver cancer:4.62e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 51.3 SYVN1 DER3, HRD1 ENSG00000162298 Synovial apoptosis inhibitor 1, synoviolin 11 65121780-65134533 Predicted membrane proteins Evidence at protein level HPA005480, HPA024300, CAB037030 Supported Supported Nucleoplasm
Endoplasmic reticulum
Plasma membrane Head and neck cancer:6.88e-4 (favourable) Expressed in all Expressed in all tonsil: 76.7 SZRD1 C1orf144, DKFZp566C0424 ENSG00000055070 SUZ RNA binding domain containing 1 1 16352575-16398145 Predicted intracellular proteins Evidence at protein level HPA024221 Uncertain Approved Nucleoplasm
Cytosol Liver cancer:5.98e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 90.0 SZT2 C1orf84, FLJ10387, FLJ34502, KIAA0467, RP11-506B15.1, SZT2A, SZT2B ENSG00000198198 Seizure threshold 2 homolog (mouse) 1 43389882-43452650 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA029012 Approved Approved Nucleoplasm
Vesicles
Actin filaments Head and neck cancer:1.47e-7 (favourable), Liver cancer:2.53e-4 (unfavourable), Lung cancer:6.20e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.0 TAB1 MAP3K7IP1 ENSG00000100324 TGF-beta activated kinase 1/MAP3K7 binding protein 1 22 39399741-39437060 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB032328, HPA039988, HPA057104 Approved Validated Nuclear speckles
Cytosol Expressed in all Expressed in all cerebral cortex: 23.2 TAB2 KIAA0733, MAP3K7IP2 ENSG00000055208 TGF-beta activated kinase 1/MAP3K7 binding protein 2 6 149218641-149411613 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA071215 Supported Cytosol Expressed in all Expressed in all parathyroid gland: 66.5 TAB3 MAP3K7IP3 ENSG00000157625 TGF-beta activated kinase 1/MAP3K7 binding protein 3 X 30827442-30975084 Predicted intracellular proteins Evidence at protein level HPA034980, HPA034981 Approved Approved Nuclear speckles
Cytosol Renal cancer:8.45e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 52.6 TACC1 ENSG00000147526 Transforming, acidic coiled-coil containing protein 1 8 38728186-38853028 Predicted intracellular proteins Evidence at protein level CAB017041, HPA024702 Approved Approved Intermediate filaments
Microtubules Renal cancer:1.06e-5 (favourable) Expressed in all Expressed in all adipose tissue: 166.0 TACO1 CCDC44 ENSG00000136463 Translational activator of mitochondrially encoded cytochrome c oxidase I 17 63600872-63608365 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021626, HPA021643, HPA024294 Supported Validated Mitochondria Pancreatic cancer:3.73e-4 (favourable) Expressed in all Expressed in all kidney: 30.5 TADA1 ADA1, hADA1, HFI1, STAF42, TADA1L ENSG00000152382 Transcriptional adaptor 1 1 166856510-166876327 Predicted intracellular proteins Evidence at protein level HPA028651 Approved Supported Nucleoplasm
Focal adhesion sites
Cytosol Expressed in all Expressed in all cerebral cortex: 23.9 TADA2B MGC21874 ENSG00000173011 Transcriptional adaptor 2B 4 7041899-7057952 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035770 Approved Approved Nuclear speckles Renal cancer:7.17e-11 (favourable), Urothelial cancer:1.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 27.4 TADA3 ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L ENSG00000171148 Transcriptional adaptor 3 3 9779860-9793011 Predicted intracellular proteins Evidence at protein level HPA042250 Approved Supported Nucleoplasm Renal cancer:5.47e-5 (favourable) Expressed in all Expressed in all testis: 71.9 TAF1 BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250 ENSG00000147133 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa X 71366239-71532374 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001075, CAB016283 Supported Validated Nucleoplasm Renal cancer:6.03e-4 (unfavourable), Lung cancer:6.54e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 25.7 TAF10 TAF2A, TAF2H, TAFII30 ENSG00000166337 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 11 6606296-6612667 Predicted intracellular proteins Evidence at protein level HPA004148, CAB022405 Supported Supported Nucleus Renal cancer:1.84e-5 (unfavourable) Expressed in all Expressed in all testis: 132.4 TAF11 TAF2I, TAFII28 ENSG00000064995 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 6 34877778-34888089 Predicted intracellular proteins Evidence at protein level HPA029326, HPA049127 Supported Nucleoplasm
Golgi apparatus Ovarian cancer:5.87e-4 (favourable) Expressed in all Expressed in all testis: 54.9 TAF12 TAF2J, TAFII20 ENSG00000120656 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 1 28589323-28643085 Predicted intracellular proteins Evidence at protein level HPA008519 Approved Renal cancer:1.36e-7 (unfavourable), Liver cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all testis: 36.9 TAF13 TAF2K, TAFII18 ENSG00000197780 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 1 109062486-109076002 Predicted intracellular proteins Evidence at protein level HPA044492 Approved Validated Nucleus
Nucleoli Liver cancer:8.74e-6 (unfavourable), Ovarian cancer:2.42e-5 (favourable) Expressed in all Expressed in all smooth muscle: 50.0 TAF15 hTAFII68, Npl3, RBP56, TAF2N ENSG00000270647 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 17 35713791-35864615 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA052059, HPA063647 Supported Validated Nucleoplasm Expressed in all Expressed in all lymph node: 61.9 TAF1C MGC:39976, SL1, TAFI110, TAFI95 ENSG00000103168 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 16 84177847-84187070 Predicted intracellular proteins Evidence at protein level HPA072229 Supported Nucleoli fibrillar center Renal cancer:8.08e-6 (unfavourable), Pancreatic cancer:1.76e-4 (favourable), Urothelial cancer:3.22e-4 (favourable) Expressed in all Expressed in all gallbladder,spleen: 15.6 TAF1D JOSD3, MGC5306, TAF(I)41 ENSG00000166012 TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 11 93729948-93784391 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA055935, HPA060385 Uncertain Supported Nucleoplasm
Microtubule organizing center Renal cancer:3.17e-7 (unfavourable) Expressed in all Expressed in all placenta: 14.0 TAF2 CIF150, TAF2B, TAFII150 ENSG00000064313 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 8 119730775-119832863 Disease related genes, Predicted intracellular proteins Evidence at protein level Endometrial cancer:2.45e-4 (unfavourable), Liver cancer:9.58e-4 (unfavourable) Expressed in all Expressed in all testis: 25.4 TAF5L PAF65B ENSG00000135801 TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 1 229593111-229626047 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA067941 Supported Nuclear speckles
Cytoplasmic bodies Expressed in all Expressed in all placenta: 20.4 TAF6 MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85 ENSG00000106290 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 7 100107070-100119841 Predicted intracellular proteins Evidence at protein level HPA006566 Uncertain Supported Nucleus
Cytosol Liver cancer:6.06e-5 (unfavourable) Expressed in all Expressed in all testis: 62.7 TAF6L PAF65A ENSG00000162227 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 11 62771303-62787342 Predicted intracellular proteins Evidence at protein level HPA067239 Approved Supported Nucleoplasm Head and neck cancer:8.98e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 12.0 TAF7 TAF2F, TAFII55 ENSG00000178913 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 5 141260225-141320821 Predicted intracellular proteins Evidence at protein level HPA006429 Approved Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all testis: 138.1 TAF8 FLJ32821, TAF(II)43, TBN ENSG00000137413 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 6 42050513-42087461 Predicted intracellular proteins Evidence at protein level HPA031730, HPA031731, HPA031734 Supported Validated Nucleus Expressed in all Expressed in all parathyroid gland: 24.9 TAF9 AD-004, CGI-137, MGC1603, MGC3647, MGC5067, TAF2G, TAFII31, TAFII32, TAFIID32 ENSG00000273841 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 5 69364743-69370013 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028930, HPA053429, HPA058961 Validated Nucleoplasm Liver cancer:1.48e-5 (unfavourable), Renal cancer:9.20e-4 (unfavourable) Expressed in all Expressed in all testis: 144.9 TAF9B DN-7, DN7, TAF9L, TAFII31L, TFIID-31 ENSG00000187325 TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa X 78129748-78139706 Predicted intracellular proteins Evidence at protein level HPA045275, HPA058961 Approved Supported Nucleoplasm Cervical cancer:5.40e-5 (favourable) Expressed in all Expressed in all smooth muscle: 44.5 TAGLN DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10 ENSG00000149591 Transgelin 11 117199321-117204782 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB001447, HPA019467 Supported Approved Microtubules
Mitochondria
Cytosol Renal cancer:2.12e-7 (unfavourable) Expressed in all Expressed in all smooth muscle: 11751.0 TAGLN2 HA1756, KIAA0120 ENSG00000158710 Transgelin 2 1 159918107-159925732 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001925 Approved Approved Actin filaments
Cytosol Renal cancer:1.92e-10 (unfavourable), Breast cancer:2.06e-5 (unfavourable), Liver cancer:7.07e-5 (unfavourable) Expressed in all Expressed in all lung: 904.3 TALDO1 ENSG00000177156 Transaldolase 1 11 747329-765024 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040373, HPA048089 Validated Nucleoplasm
Cytosol Liver cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all esophagus: 263.9 TANGO2 C22orf25, DKFZp761P1121 ENSG00000183597 Transport and golgi organization 2 homolog 22 20017014-20065926 Predicted intracellular proteins Evidence at protein level HPA003080 Approved Approved Pancreatic cancer:3.01e-4 (favourable) Expressed in all Expressed in all heart muscle: 46.6 TANK I-TRAF, TRAF2 ENSG00000136560 TRAF family member-associated NFKB activator 2 161136908-161236221 Predicted intracellular proteins Evidence at protein level CAB010345, HPA037675, HPA037676 Approved Supported Nucleoli
Cytosol Renal cancer:2.78e-6 (unfavourable), Liver cancer:2.90e-4 (unfavourable) Expressed in all Expressed in all breast: 67.9 TAOK1 FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1 ENSG00000160551 TAO kinase 1 17 29390464-29551904 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007669 Approved Expressed in all Expressed in all parathyroid gland: 40.8 TAOK2 KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2 ENSG00000149930 TAO kinase 2 16 29973641-29992261 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA010650 Approved Supported Nucleus
Nucleoli
Cytosol Endometrial cancer:3.87e-5 (favourable), Colorectal cancer:2.51e-4 (unfavourable), Renal cancer:3.66e-4 (favourable), Pancreatic cancer:4.78e-4 (favourable) Expressed in all Expressed in all testis: 36.9 TAOK3 DPK, JIK, MAP3K18 ENSG00000135090 TAO kinase 3 12 118149801-118372945 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017160 Approved Approved Mitochondria Expressed in all Expressed in all cerebral cortex: 49.0 TAPBP TAPA ENSG00000231925 TAP binding protein (tapasin) 6 33299694-33314387 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007066 Approved Breast cancer:2.76e-4 (favourable), Melanoma:6.29e-4 (favourable) Expressed in all Expressed in all spleen: 31.4 TAPBPL FLJ10143, TAPBP-R, TAPBPR ENSG00000139192 TAP binding protein-like 12 6451690-6466517 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA039545 Uncertain Renal cancer:6.04e-5 (favourable), Breast cancer:1.98e-4 (favourable), Urothelial cancer:7.86e-4 (favourable) Expressed in all Expressed in all thyroid gland: 39.0 TAPT1 FLJ90013 ENSG00000169762 Transmembrane anterior posterior transformation 1 4 16160505-16227410 Predicted membrane proteins Evidence at protein level HPA042567, HPA048658 Approved Approved Vesicles Urothelial cancer:4.18e-4 (favourable), Pancreatic cancer:5.34e-4 (favourable), Renal cancer:8.52e-4 (favourable), Endometrial cancer:9.75e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 21.6 TARBP1 TRM3, TRP-185 ENSG00000059588 TAR (HIV-1) RNA binding protein 1 1 234391313-234479103 Predicted intracellular proteins Evidence at protein level CAB020810, HPA024632 Uncertain Approved Nuclear speckles Renal cancer:5.14e-10 (unfavourable) Expressed in all Expressed in all parathyroid gland: 15.8 TARBP2 ENSG00000139546 TAR (HIV-1) RNA binding protein 2 12 53500921-53506431 Predicted intracellular proteins Evidence at protein level HPA051181, HPA061454, CAB069406 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:4.75e-6 (unfavourable), Liver cancer:3.09e-4 (unfavourable) Expressed in all Expressed in all placenta: 18.6 TARDBP ALS10, TDP-43 ENSG00000120948 TAR DNA binding protein 1 11012344-11026420 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003703, HPA017284 Supported Validated Nucleoplasm Liver cancer:1.20e-7 (unfavourable), Cervical cancer:1.15e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 129.0 TARS ENSG00000113407 Threonyl-tRNA synthetase 5 33440696-33469539 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037425 Approved Supported Actin filaments
Cytosol Liver cancer:9.88e-7 (unfavourable), Breast cancer:6.14e-5 (unfavourable), Endometrial cancer:5.17e-4 (unfavourable), Renal cancer:9.63e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 44.3 TARS2 FLJ12528, TARSL1 ENSG00000143374 Threonyl-tRNA synthetase 2, mitochondrial (putative) 1 150487364-150507609 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA028626 Approved Approved Nucleoplasm
Intermediate filaments
Cytosol Expressed in all Expressed in all parathyroid gland: 28.8 TARSL2 FLJ25005 ENSG00000185418 Threonyl-tRNA synthetase-like 2 15 101653598-101724604 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063963, HPA066697 Uncertain Approved Cytosol Expressed in all Expressed in all cerebral cortex: 15.7 TATDN1 CDA11 ENSG00000147687 TatD DNase domain containing 1 8 124488485-124539458 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023634, HPA053045 Uncertain Supported Nucleoplasm Pancreatic cancer:2.53e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.9 TATDN2 KIAA0218 ENSG00000157014 TatD DNase domain containing 2 3 10248023-10281218 Predicted intracellular proteins Evidence at protein level HPA036822, HPA058001 Approved Supported Nucleus
Nuclear speckles
Cytosol Pancreatic cancer:4.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 37.6 TATDN3 ENSG00000203705 TatD DNase domain containing 3 1 212791828-212816626 Predicted intracellular proteins Evidence at protein level HPA032092 Approved Approved Nucleoplasm
Golgi apparatus
Focal adhesion sites Renal cancer:1.59e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 22.2 TAX1BP1 CALCOCO3, TXBP151 ENSG00000106052 Tax1 (human T-cell leukemia virus type I) binding protein 1 7 27739331-27844564 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA024432 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:2.80e-6 (favourable), Pancreatic cancer:1.06e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 181.0 TAX1BP3 TIP-1 ENSG00000213977 Tax1 (human T-cell leukemia virus type I) binding protein 3 17 3662896-3668682 Predicted intracellular proteins Evidence at protein level HPA046410, HPA063078 Approved Approved Nucleoli fibrillar center
Vesicles
Actin filaments Glioma:1.66e-4 (unfavourable), Lung cancer:1.76e-4 (unfavourable), Renal cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 226.7 TAZ BTHS, CMD3A, EFE, EFE2, G4.5, XAP-2 ENSG00000102125 Tafazzin X 154411518-154421726 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039557 Approved Approved Plasma membrane Renal cancer:1.22e-7 (unfavourable), Cervical cancer:5.70e-4 (favourable) Expressed in all Expressed in all spleen: 21.2 TBC1D1 KIAA1108, TBC, TBC1 ENSG00000065882 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 4 37891087-38139175 Predicted intracellular proteins Evidence at protein level HPA041816, HPA058158 Approved Uncertain Nucleoli Renal cancer:1.47e-8 (favourable), Lung cancer:5.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 247.3 TBC1D10B DKFZP434P1750, EPI64B, FLJ13130, Rab27A-GAPbeta ENSG00000169221 TBC1 domain family, member 10B 16 30357102-30370264 Predicted intracellular proteins Evidence at protein level HPA048894 Uncertain Liver cancer:8.94e-5 (unfavourable), Colorectal cancer:1.35e-4 (unfavourable) Expressed in all Expressed in all testis: 36.0 TBC1D13 FLJ10743 ENSG00000107021 TBC1 domain family, member 13 9 128787204-128810432 Predicted intracellular proteins Evidence at protein level HPA045865 Approved Approved Nucleoli Renal cancer:1.58e-7 (favourable), Pancreatic cancer:3.14e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 46.3 TBC1D14 KIAA1322 ENSG00000132405 TBC1 domain family, member 14 4 6909242-7033118 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036930, HPA067398 Approved Supported Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:5.28e-10 (favourable) Expressed in all Expressed in all cerebral cortex: 67.7 TBC1D15 DKFZp761D0223, FLJ12085 ENSG00000121749 TBC1 domain family, member 15 12 71839707-71927248 Predicted intracellular proteins Evidence at protein level HPA013388, HPA015592 Supported Supported Mitochondria
Cytosol Renal cancer:5.34e-4 (favourable), Cervical cancer:7.06e-4 (favourable) Expressed in all Expressed in all thyroid gland: 50.8 TBC1D17 FLJ12168 ENSG00000104946 TBC1 domain family, member 17 19 49877425-49888749 Predicted intracellular proteins Evidence at protein level HPA068119 Uncertain Pancreatic cancer:4.02e-4 (favourable), Head and neck cancer:7.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 29.9 TBC1D20 C20orf140, dJ852M4.2 ENSG00000125875 TBC1 domain family, member 20 20 435480-462553 Disease related genes, Predicted membrane proteins Evidence at protein level HPA043613 Approved Expressed in all Expressed in all parathyroid gland: 30.7 TBC1D22A C22orf4 ENSG00000054611 TBC1 domain family, member 22A 22 46762617-47175699 Predicted intracellular proteins Evidence at protein level HPA001173 Uncertain Approved Nucleoplasm
Golgi apparatus
Vesicles Liver cancer:2.42e-4 (unfavourable), Ovarian cancer:6.94e-4 (unfavourable) Expressed in all Expressed in all spleen: 22.4 TBC1D22B C6orf197, dJ744I24.2, FLJ20337 ENSG00000065491 TBC1 domain family, member 22B 6 37257772-37332970 Predicted intracellular proteins Evidence at protein level HPA027908, HPA027909, HPA027910 Uncertain Uncertain Nucleoplasm
Cytosol Endometrial cancer:8.15e-5 (unfavourable) Expressed in all Expressed in all testis: 18.7 TBC1D23 FLJ11046 ENSG00000036054 TBC1 domain family, member 23 3 100261000-100325251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038151, HPA038152 Approved Validated Golgi apparatus Endometrial cancer:5.37e-4 (unfavourable) Expressed in all Expressed in all testis: 32.8 TBC1D24 DFNA65, DFNB86, KIAA1171, TLDC6 ENSG00000162065 TBC1 domain family, member 24 16 2475118-2505734 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA044712, HPA068080 Uncertain Supported Plasma membrane
Cell Junctions Breast cancer:3.22e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 23.4 TBC1D25 OATL1 ENSG00000068354 TBC1 domain family, member 25 X 48539457-48562609 Predicted intracellular proteins Evidence at protein level HPA029197 Approved Expressed in all Expressed in all parathyroid gland: 12.7 TBC1D2B KIAA1055 ENSG00000167202 TBC1 domain family, member 2B 15 77984036-78077724 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048174, HPA052663 Approved Approved Vesicles Expressed in all Expressed in all lung: 57.6 TBC1D4 AS160, DKFZp779C0666, KIAA0603 ENSG00000136111 TBC1 domain family, member 4 13 75284665-75482114 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040145, HPA059885 Approved Supported Cytosol Renal cancer:1.07e-11 (favourable) Expressed in all Expressed in all adrenal gland: 83.2 TBC1D5 KIAA0210 ENSG00000131374 TBC1 domain family, member 5 3 17157162-18444817 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA035125, HPA035126 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:1.75e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 55.9 TBC1D7 dJ257A7.3, FLJ32666 ENSG00000145979 TBC1 domain family, member 7 6 13266542-13328583 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034748 Approved Renal cancer:2.03e-7 (unfavourable), Ovarian cancer:4.98e-5 (favourable) Expressed in all Expressed in all testis: 24.4 TBC1D8 AD3, HBLP1, VRP ENSG00000204634 TBC1 domain family, member 8 (with GRAM domain) 2 101007617-101252866 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB015211, HPA037496 Uncertain Supported Nucleus Colorectal cancer:6.73e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 44.7 TBC1D8B FLJ20298, RP11-321G1.1 ENSG00000133138 TBC1 domain family, member 8B (with GRAM domain) X 106802680-106876145 Predicted intracellular proteins Evidence at protein level HPA023883, HPA027527 Approved Supported Approved Cytosol Mixed Expressed in all adrenal gland: 26.6 TBC1D9B KIAA0676 ENSG00000197226 TBC1 domain family, member 9B (with GRAM domain) 5 179862066-179907859 Predicted intracellular proteins Evidence at protein level HPA038350 Approved Approved Nucleus
Nucleoli fibrillar center
Plasma membrane Thyroid cancer:3.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 60.9 TBCA ENSG00000171530 Tubulin folding cofactor A 5 77691166-77868780 Predicted intracellular proteins Evidence at protein level HPA036487 Approved Supported Nucleoli
Microtubules Expressed in all Expressed in all adrenal gland: 307.1 TBCB CG22, CKAP1, CKAPI ENSG00000105254 Tubulin folding cofactor B 19 36114289-36125947 Predicted intracellular proteins Evidence at protein level HPA041428, HPA041722 Approved Supported Cytosol Liver cancer:2.09e-4 (unfavourable), Pancreatic cancer:3.11e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 250.6 TBCC CFC ENSG00000124659 Tubulin folding cofactor C 6 42744481-42746096 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA035073, HPA035074 Approved Validated Cytosol Expressed in all Expressed in all lymph node: 33.2 TBCCD1 FLJ10560 ENSG00000113838 TBCC domain containing 1 3 186546073-186570543 Predicted intracellular proteins Evidence at protein level Liver cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all testis: 35.4 TBCD ENSG00000141556 Tubulin folding cofactor D 17 82752064-82945922 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA045200 Approved Liver cancer:2.39e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 58.5 TBCE HRD, KCS, KCS1, pac2 ENSG00000116957 Tubulin folding cofactor E 1 235367360-235448968 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026552, HPA026557 Uncertain Renal cancer:7.87e-13 (unfavourable), Head and neck cancer:7.90e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.1 TBCEL LRRC35, MGC10233 ENSG00000154114 Tubulin folding cofactor E-like 11 121024072-121090775 Predicted intracellular proteins Evidence at protein level HPA038593, HPA038594 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 35.1 TBK1 NAK ENSG00000183735 TANK-binding kinase 1 12 64451880-64502108 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins Evidence at protein level HPA045797, HPA060211 Uncertain Supported Nucleoplasm Renal cancer:4.20e-6 (unfavourable), Liver cancer:3.30e-4 (unfavourable), Melanoma:3.48e-4 (unfavourable) Expressed in all Expressed in all testis: 49.2 TBKBP1 KIAA0775, ProSAPiP2 ENSG00000198933 TBK1 binding protein 1 17 47694081-47712050 Predicted intracellular proteins Evidence at protein level HPA062347, HPA064856 Approved Approved Nucleoplasm Pancreatic cancer:8.14e-6 (favourable), Urothelial cancer:1.59e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 33.0 TBL1X EBI, TBL1 ENSG00000101849 Transducin (beta)-like 1X-linked X 9463295-9719743 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005363, HPA067703 Approved Approved Nucleus
Nucleoli Pancreatic cancer:1.32e-4 (favourable), Renal cancer:4.58e-4 (favourable), Breast cancer:8.50e-4 (unfavourable) Expressed in all Expressed in all endometrium: 63.5 TBL1XR1 C21, DC42, FLJ12894, IRA1, TBLR1 ENSG00000177565 Transducin (beta)-like 1 X-linked receptor 1 3 177019355-177197396 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019182 Supported Approved Nucleoplasm Liver cancer:1.08e-7 (unfavourable), Renal cancer:4.25e-5 (unfavourable), Glioma:7.23e-5 (favourable) Expressed in all Expressed in all thyroid gland: 61.2 TBP GTF2D1, SCA17, TFIID ENSG00000112592 TATA box binding protein 6 170554302-170572870 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB009442, HPA049805 Approved Supported Nucleoplasm Liver cancer:1.51e-7 (unfavourable) Expressed in all Expressed in all testis: 65.3 TBRG1 FLJ14621, NIAM, TB-5 ENSG00000154144 Transforming growth factor beta regulator 1 11 124622836-124635398 Predicted intracellular proteins Evidence at protein level HPA055645, HPA068022 Validated Nucleus Expressed in all Expressed in all spleen: 16.3 TBRG4 Cpr2, FASTKD4, H_TD2522F11.8, KIAA0948 ENSG00000136270 Transforming growth factor beta regulator 4 7 45100100-45112047 Predicted intracellular proteins Evidence at protein level HPA020582, HPA050430 Approved Validated Mitochondria Liver cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all testis: 41.8 TCAF1 FAM115A, KIAA0738 ENSG00000198420 TRPM8 channel-associated factor 1 7 143851375-143902198 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011732, HPA061989 Approved Supported Nucleoplasm
Mitochondria Ovarian cancer:5.93e-4 (favourable) Expressed in all Expressed in all placenta: 115.3 TCAIM C3orf23, DKFZp313N0621, TOAG-1 ENSG00000179152 T cell activation inhibitor, mitochondrial 3 44338119-44409451 Predicted intracellular proteins Evidence at transcript level Renal cancer:2.19e-7 (favourable), Urothelial cancer:2.81e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 22.6 TCEA1 GTF2S, SII, TCEA, TF2S, TFIIS ENSG00000187735 Transcription elongation factor A (SII), 1 8 53966552-54022529 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043786 Approved Supported Nucleus
Nucleoli Renal cancer:3.75e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 199.1 TCEA2 TFIIS ENSG00000171703 Transcription elongation factor A (SII), 2 20 64049836-64072347 Predicted intracellular proteins Evidence at protein level HPA043836 Approved Supported Nucleoplasm
Centrosome Expressed in all Expressed in all cerebral cortex: 74.0 TCEAL1 p21, pp21, SIIR, WEX9 ENSG00000172465 Transcription elongation factor A (SII)-like 1 X 103628704-103630953 Predicted intracellular proteins Evidence at protein level HPA057345 Supported Nucleoplasm Expressed in all Expressed in all ovary: 146.1 TCEAL3 MGC15737, WEX8 ENSG00000196507 Transcription elongation factor A (SII)-like 3 X 103607451-103629690 Predicted intracellular proteins Evidence at protein level HPA045564, HPA058982 Uncertain Lung cancer:4.05e-4 (favourable), Ovarian cancer:8.33e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 98.2 TCEAL4 FLJ21174, WEX7 ENSG00000133142 Transcription elongation factor A (SII)-like 4 X 103576231-103587736 Predicted intracellular proteins Evidence at protein level Head and neck cancer:3.11e-5 (unfavourable), Lung cancer:2.75e-4 (favourable) Expressed in all Expressed in all ovary: 557.2 TCEAL8 MGC45400, WEX3 ENSG00000180964 Transcription elongation factor A (SII)-like 8 X 103252995-103255203 Predicted intracellular proteins Evidence at protein level HPA059115 Uncertain Approved Nucleoplasm Head and neck cancer:8.53e-6 (unfavourable) Expressed in all Expressed in all epididymis: 147.2 TCEB1 SIII ENSG00000154582 Transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8 73939169-73972287 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA078113 Approved Cell Junctions Breast cancer:6.48e-4 (unfavourable) Expressed in all Expressed in all testis: 162.2 TCEB2 SIII ENSG00000103363 Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 16 2771414-2777297 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all fallopian tube: 350.8 TCEB3 SIII, TCEB3A ENSG00000011007 Transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 1 23743155-23762059 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005910 Approved Approved Nuclear speckles
Cytosol Liver cancer:1.44e-5 (unfavourable) Expressed in all Expressed in all lung: 38.6 TCERG1 CA150, TAF2S, Urn1 ENSG00000113649 Transcription elongation regulator 1 5 146447311-146511961 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA064854, HPA069752, HPA069808 Supported Validated Nucleoplasm Renal cancer:4.70e-11 (unfavourable), Liver cancer:5.34e-5 (unfavourable) Expressed in all Expressed in all appendix,lymph node: 21.0 TCF12 bHLHb20, HEB, HsT17266, HTF4 ENSG00000140262 Transcription factor 12 15 56918623-57299281 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level CAB004432, HPA065827 Approved Supported Nucleoplasm
Nuclear speckles Renal cancer:5.24e-5 (unfavourable), Melanoma:8.89e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 115.4 TCF25 KIAA1049, Nulp1 ENSG00000141002 Transcription factor 25 (basic helix-loop-helix) 16 89873586-89911384 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041699, HPA041786 Uncertain Endometrial cancer:6.95e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 124.9 TCF3 bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, VDIR ENSG00000071564 Transcription factor 3 19 1609290-1652605 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB018351, HPA049808, HPA062476 Approved Validated Nucleoplasm Renal cancer:1.53e-4 (unfavourable), Liver cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all lymph node: 104.6 TCF4 bHLHb19, E2-2, ITF2, SEF2-1B ENSG00000196628 Transcription factor 4 18 55222331-55664787 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB020722, HPA025958 Approved Approved Nucleoplasm
Cytosol Renal cancer:7.24e-5 (unfavourable), Urothelial cancer:9.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 90.8 TCF7L2 TCF-4, TCF4 ENSG00000148737 Transcription factor 7-like 2 (T-cell specific, HMG-box) 10 112950250-113167678 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB013535, HPA038800 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all endometrium: 33.6 TCFL5 bHLHe82, CHA, E2BP-1, Figlb ENSG00000101190 Transcription factor-like 5 (basic helix-loop-helix) 20 62841115-62861763 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055223 Approved Supported Nucleoplasm Endometrial cancer:3.24e-4 (unfavourable) Expressed in all Expressed in all testis: 143.8 TCHP MGC10854, TpMs ENSG00000139437 Trichoplein, keratin filament binding 12 109900264-109983841 Predicted intracellular proteins Evidence at protein level HPA038638, HPA061543 Supported Supported Plasma membrane
Centrosome
Cytosol Stomach cancer:5.52e-4 (favourable) Expressed in all Expressed in all skin: 32.7 TCIRG1 a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7 ENSG00000110719 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 11 68039016-68050895 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038742 Approved Approved Mitochondria Renal cancer:1.50e-11 (unfavourable), Urothelial cancer:9.45e-6 (favourable) Expressed in all Expressed in all spleen: 83.5 TCN2 D22S676, D22S750, TC2 ENSG00000185339 Transcobalamin II 22 30606838-30627278 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000837 Approved Cytosol Liver cancer:2.64e-4 (unfavourable), Cervical cancer:3.47e-4 (favourable) Expressed in all Expressed in all kidney: 121.6 TCOF1 TCS, treacle ENSG00000070814 Treacher Collins-Franceschetti syndrome 1 5 150357639-150400308 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033199, HPA038237, HPA038238 Supported Validated Nucleus
Nucleoli fibrillar center Liver cancer:2.26e-8 (unfavourable), Renal cancer:2.62e-5 (unfavourable) Expressed in all Expressed in all lymph node: 22.3 TCP1 CCT1, Ccta, D6S230E ENSG00000120438 T-complex 1 6 159778498-159789749 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB017460, HPA027337, HPA031082 Approved Liver cancer:1.49e-5 (unfavourable), Breast cancer:8.88e-5 (unfavourable) Expressed in all Expressed in all testis: 323.1 TCP11L2 MGC40368 ENSG00000166046 T-complex 11, testis-specific-like 2 12 106301929-106347015 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039483, HPA042188 Uncertain Supported Nuclear speckles Head and neck cancer:9.52e-4 (favourable) Mixed Expressed in all fallopian tube: 26.2 TCTA ENSG00000145022 T-cell leukemia translocation altered 3 49412206-49416475 Disease related genes, Predicted membrane proteins Evidence at protein level HPA007342 Approved Approved Cytosol Renal cancer:5.00e-15 (favourable), Lung cancer:6.76e-4 (favourable) Expressed in all Expressed in all thyroid gland: 75.9 TCTN3 C10orf61, DKFZP564D116, JBTS18, TECT3 ENSG00000119977 Tectonic family member 3 10 95663396-95694143 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA026987 Approved Approved Microtubules Endometrial cancer:5.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 135.3 TDG ENSG00000139372 Thymine DNA glycosylase 12 103965804-103988874 Enzymes, Predicted intracellular proteins Evidence at protein level HPA052263 Supported Supported Nucleoplasm Renal cancer:1.90e-10 (unfavourable), Liver cancer:6.27e-5 (unfavourable), Melanoma:6.90e-5 (unfavourable) Expressed in all Expressed in all placenta: 23.6 TDP2 TTRAP ENSG00000111802 Tyrosyl-DNA phosphodiesterase 2 6 24649977-24667033 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB073398, HPA074011 Supported Supported Nucleoplasm
Nuclear bodies Ovarian cancer:2.53e-7 (favourable), Urothelial cancer:1.47e-5 (favourable), Prostate cancer:1.86e-4 (unfavourable) Expressed in all Expressed in all small intestine: 193.0 TDRD3 FLJ21007 ENSG00000083544 Tudor domain containing 3 13 60396457-60573878 Predicted intracellular proteins Evidence at protein level CAB034925 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:2.77e-4 (favourable) Expressed in all Expressed in all testis: 22.7 TDRD7 PCTAIRE2BP ENSG00000196116 Tudor domain containing 7 9 97411950-97496125 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB020800, HPA024529 Approved Renal cancer:4.76e-5 (favourable), Liver cancer:5.91e-4 (unfavourable) Expressed in all Expressed in all testis: 63.8 TECPR1 DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358 ENSG00000205356 Tectonin beta-propeller repeat containing 1 7 98214624-98252251 Predicted intracellular proteins Evidence at protein level HPA021061 Approved Supported Vesicles Pancreatic cancer:8.12e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 19.2 TECR GPSN2, MRT14, SC2, TER ENSG00000099797 Trans-2,3-enoyl-CoA reductase 19 14517085-14565980 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029780, HPA056488 Supported Supported Endoplasmic reticulum Urothelial cancer:2.60e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 397.0 TELO2 hCLK2, KIAA0683, TEL2 ENSG00000100726 Telomere maintenance 2 16 1493344-1510457 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041348, HPA041473 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all spleen: 15.8 TEN1 C17orf106, FLJ39785 ENSG00000257949 TEN1 CST complex subunit 17 75979220-76000586 Predicted intracellular proteins Evidence at protein level HPA065069 Supported Nucleus Not detected Expressed in all skin: 29.9 TERF1 PIN2, TRBF1, TRF, TRF1 ENSG00000147601 Telomeric repeat binding factor (NIMA-interacting) 1 8 73008864-73048122 Predicted intracellular proteins Evidence at protein level HPA048379 Supported Nucleoli fibrillar center
Nuclear bodies Renal cancer:6.68e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 45.9 TERF2 TRBF2, TRF2 ENSG00000132604 Telomeric repeat binding factor 2 16 69355561-69408571 Predicted intracellular proteins Evidence at protein level HPA001907, HPA002735, CAB010451 Supported Supported Nuclear bodies Expressed in all Expressed in all lymph node: 42.7 TERF2IP RAP1 ENSG00000166848 Telomeric repeat binding factor 2, interacting protein 16 75647786-75761872 Predicted intracellular proteins Evidence at protein level HPA006719, CAB018660, CAB018749 Supported Supported Nucleoplasm
Nuclear bodies Renal cancer:2.15e-5 (favourable), Ovarian cancer:6.14e-5 (favourable), Pancreatic cancer:1.46e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 221.9 TES DKFZP586B2022, TESS-2, TESTIN ENSG00000135269 Testin LIM domain protein 7 116210493-116258783 Predicted intracellular proteins Evidence at protein level HPA015269, HPA018123 Approved Supported Plasma membrane
Cell Junctions
Focal adhesion sites
Cytosol Pancreatic cancer:1.20e-5 (unfavourable), Renal cancer:8.71e-5 (favourable) Expressed in all Expressed in all seminal vesicle: 269.2 TESK1 ENSG00000107140 Testis-specific kinase 1 9 35605305-35610041 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:9.68e-4 (unfavourable) Expressed in all Expressed in all testis: 46.2 TEX10 bA208F1.2, FLJ20287, Ipi1 ENSG00000136891 Testis expressed 10 9 100302077-100352939 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Liver cancer:4.46e-5 (unfavourable) Expressed in all Expressed in all testis: 41.6 TEX2 HT008, KIAA1738, TMEM96 ENSG00000136478 Testis expressed 2 17 64147227-64263301 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020648, HPA057116 Approved Approved Nucleus Colorectal cancer:3.90e-6 (favourable) Expressed in all Expressed in all testis: 99.2 TEX261 MGC32043, TEG-261 ENSG00000144043 Testis expressed 261 2 70985938-70994945 Predicted membrane proteins Evidence at transcript level HPA016631 Approved Approved Nucleoplasm
Cytosol Liver cancer:4.23e-4 (unfavourable), Endometrial cancer:6.17e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 91.4 TEX264 FLJ13935, ZSIG11 ENSG00000164081 Testis expressed 264 3 51662693-51704323 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB005002, HPA017739 Supported Supported Nucleoli
Cytosol Renal cancer:7.95e-9 (favourable), Pancreatic cancer:5.67e-4 (favourable) Expressed in all Expressed in all testis: 112.9 TFAM TCF6, TCF6L2 ENSG00000108064 Transcription factor A, mitochondrial 10 58385022-58399221 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA040648, HPA063684 Supported Validated Mitochondria Renal cancer:2.22e-5 (favourable), Ovarian cancer:2.74e-4 (favourable), Endometrial cancer:8.73e-4 (unfavourable) Expressed in all Expressed in all testis: 62.0 TFB2M FLJ22661, FLJ23182, Hkp1 ENSG00000162851 Transcription factor B2, mitochondrial 1 246540560-246566324 Predicted intracellular proteins Evidence at protein level HPA028482, HPA030265, HPA061095 Approved Validated Mitochondria Expressed in all Expressed in all adrenal gland: 29.7 TFCP2 CP2, LBP-1C, LSF, TFCP2C ENSG00000135457 Transcription factor CP2 12 51093663-51173134 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA070247 Supported Nucleoplasm
Cytosol Melanoma:1.18e-4 (unfavourable), Liver cancer:1.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 43.6 TFDP1 Dp-1, DP1, DRTF1 ENSG00000198176 Transcription factor Dp-1 13 113584721-113641470 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB033605, HPA044754, HPA068909 Supported Validated Nucleoplasm Liver cancer:1.03e-4 (unfavourable), Stomach cancer:6.17e-4 (favourable), Renal cancer:7.57e-4 (favourable) Expressed in all Expressed in all bone marrow: 100.1 TFDP2 Dp-2 ENSG00000114126 Transcription factor Dp-2 (E2F dimerization partner 2) 3 141944428-142149544 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB018396 Supported Supported Nucleus
Vesicles Cervical cancer:6.32e-4 (favourable), Renal cancer:9.84e-4 (favourable) Expressed in all Expressed in all testis: 127.0 TFE3 bHLHe33, TFEA ENSG00000068323 Transcription factor binding to IGHM enhancer 3 X 49028726-49043486 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023881 Approved Supported Nucleoplasm
Cytosol Renal cancer:2.19e-8 (unfavourable), Liver cancer:6.03e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 24.2 TFEB bHLHe35, TCFEB ENSG00000112561 Transcription factor EB 6 41683978-41736259 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049532 Supported Nucleoplasm Renal cancer:1.06e-5 (favourable), Pancreatic cancer:4.77e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 53.4 TFG FLJ36137, SPG57, TF6 ENSG00000114354 TRK-fused gene 3 100709331-100748966 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019473, HPA052206 Approved Approved Vesicles
Cytosol Pancreatic cancer:1.50e-4 (unfavourable), Liver cancer:5.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 161.6 TFIP11 DKFZP434B194, Spp382, TIP39 ENSG00000100109 Tuftelin interacting protein 11 22 26491225-26512505 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027085 Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 50.8 TFPI EPI, LACI, TFI, TFPI1 ENSG00000003436 Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2 187464230-187565760 Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins Evidence at protein level HPA005575, CAB020842 Supported Approved Intermediate filaments
Cytosol Cervical cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all placenta: 340.4 TFRC CD71, p90, TFR1 ENSG00000072274 Transferrin receptor 3 196027183-196082189 Cancer-related genes, CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB000153, HPA028598 Supported Supported Endosomes
Lysosomes Liver cancer:1.15e-4 (unfavourable), Thyroid cancer:2.96e-4 (unfavourable), Cervical cancer:3.67e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 157.6 TGDS SDR2E1, TDPGD ENSG00000088451 TDP-glucose 4,6-dehydratase 13 94574051-94596257 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039927, HPA040857 Approved Approved Nucleus
Nucleoli
Intermediate filaments Prostate cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 21.6 TGFB1 CED, DPD1, TGFB, TGFbeta ENSG00000105329 Transforming growth factor, beta 1 19 41301587-41353911 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000361, CAB073543 Approved Uncertain Cytosol Renal cancer:1.19e-8 (unfavourable), Head and neck cancer:3.38e-4 (unfavourable) Expressed in all Expressed in all spleen: 86.1 TGFBI BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1 ENSG00000120708 Transforming growth factor, beta-induced, 68kDa 5 136028895-136063818 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008612, HPA017019 Supported Approved Cytosol Renal cancer:7.82e-10 (unfavourable), Cervical cancer:1.03e-5 (unfavourable), Ovarian cancer:1.14e-5 (unfavourable), Endometrial cancer:1.17e-4 (favourable) Expressed in all Expressed in all placenta: 606.0 TGFBR1 ACVRLK4, ALK-5, ESS1, MSSE ENSG00000106799 Transforming growth factor, beta receptor 1 9 99104038-99154192 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level CAB002441, CAB031481, HPA056473 Uncertain Supported Vesicles
Plasma membrane Expressed in all Expressed in all placenta: 69.3 TGFBR2 MFS2 ENSG00000163513 Transforming growth factor, beta receptor II (70/80kDa) 3 30606502-30694142 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins Evidence at protein level CAB073537 Supported Plasma membrane Expressed in all Expressed in all adipose tissue: 290.3 TGFBR3 betaglycan, BGCAN ENSG00000069702 Transforming growth factor, beta receptor III 1 91680343-91906335 Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008257, CAB018971 Supported Approved Cytosol Thyroid cancer:3.14e-4 (unfavourable), Endometrial cancer:3.36e-4 (unfavourable), Head and neck cancer:4.84e-4 (favourable), Renal cancer:4.99e-4 (favourable) Expressed in all Expressed in all ovary: 99.5 TGFBRAP1 TRAP-1, TRAP1 ENSG00000135966 Transforming growth factor, beta receptor associated protein 1 2 105264391-105330034 Predicted intracellular proteins Evidence at protein level HPA037672, HPA038397 Approved Approved Vesicles Expressed in all Expressed in all parathyroid gland: 20.5 TGIF1 HPE4, TGIF ENSG00000177426 TGFB-induced factor homeobox 1 18 3411608-3459978 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062160 Supported Nucleoplasm Pancreatic cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all epididymis: 159.9 TGOLN2 TGN38, TGN46, TGN48, TGN51, TTGN2 ENSG00000152291 Trans-golgi network protein 2 2 85318020-85328425 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011489, HPA012609, HPA012723 Supported Validated Nucleoplasm
Golgi apparatus Expressed in all Expressed in all thyroid gland: 145.8 THADA FLJ21877, GITA, KIAA1767 ENSG00000115970 Thyroid adenoma associated 2 43230836-43596046 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035191, HPA035192 Uncertain Approved Cytosol Liver cancer:6.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 26.4 THAP11 CTG-B43a, CTG-B45d, HRIHFB2206 ENSG00000168286 THAP domain containing 11 16 67842082-67844195 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041434, HPA042189 Supported Validated Nucleoplasm
Cytokinetic bridge Expressed in all Expressed in all fallopian tube: 25.1 THAP3 ENSG00000041988 THAP domain containing, apoptosis associated protein 3 1 6624866-6635586 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA067114 Approved Approved Nucleus Colorectal cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all ovary: 17.8 THAP4 CGI-36 ENSG00000176946 THAP domain containing 4 2 241584405-241637449 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA044982, HPA053448 Uncertain Approved Nucleoplasm
Nuclear speckles Renal cancer:1.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 81.6 THAP5 DKFZp313O1132 ENSG00000177683 THAP domain containing 5 7 108554543-108569750 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043170, HPA051488 Approved Validated Nucleus Renal cancer:8.99e-4 (favourable) Expressed in all Expressed in all testis: 46.5 THAP6 MGC30052 ENSG00000174796 THAP domain containing 6 4 75513946-75550473 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035767 Uncertain Approved Nucleus
Centrosome Expressed in all Expressed in all testis: 44.1 THAP7 MGC10963 ENSG00000184436 THAP domain containing 7 22 20999104-21002196 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003083 Approved Approved Nucleus
Vesicles Expressed in all Expressed in all testis: 20.4 THBD CD141 ENSG00000178726 Thrombomodulin 20 23045633-23049741 Candidate cardiovascular disease genes, CD markers, Disease related genes, Predicted membrane proteins Evidence at protein level CAB002425, HPA002982 Supported Approved Nucleoplasm
Cytosol Expressed in all Expressed in all lung: 73.4 THBS1 THBS, THBS-1, TSP, TSP-1, TSP1 ENSG00000137801 Thrombospondin 1 15 39581079-39599466 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB033678, HPA059756 Approved Approved Plasma membrane Renal cancer:8.47e-5 (unfavourable), Stomach cancer:8.50e-4 (unfavourable) Expressed in all Expressed in all appendix: 585.7 THBS3 ENSG00000169231 Thrombospondin 3 1 155195588-155209051 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA006293 Approved Renal cancer:2.38e-12 (unfavourable), Endometrial cancer:1.44e-4 (unfavourable), Colorectal cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 41.6 THEM4 CTMP ENSG00000159445 Thioesterase superfamily member 4 1 151873584-151909808 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028161 Approved Liver cancer:1.38e-4 (unfavourable), Pancreatic cancer:2.51e-4 (favourable) Expressed in all Expressed in all kidney: 11.6 THEM6 C8orf55, DSCD75 ENSG00000130193 Thioesterase superfamily member 6 8 142727203-142736927 Predicted intracellular proteins Evidence at protein level HPA023255 Uncertain Approved Nuclear speckles
Cytosol Renal cancer:6.66e-7 (favourable), Urothelial cancer:4.49e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.4 THOC2 CXorf3, dJ506G2.1, MRX12, MRX35, THO2 ENSG00000125676 THO complex 2 X 123600561-123733056 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047921 Supported Approved Nucleoplasm Liver cancer:5.77e-5 (unfavourable) Expressed in all Expressed in all epididymis: 45.9 THOC3 MGC5469, TEX1 ENSG00000051596 THO complex 3 5 175917873-176034680 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA042764, HPA044009, HPA045071 Approved Validated Nucleoplasm Expressed in all Expressed in all epididymis: 76.5 THOC5 C22orf19, Fmip, fSAP79, KIAA0983, PK1.3 ENSG00000100296 THO complex 5 22 29505879-29555216 Predicted intracellular proteins Evidence at protein level HPA048402 Supported Nucleoplasm Liver cancer:3.76e-6 (unfavourable), Renal cancer:3.65e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 42.7 THOC6 fSAP35, MGC2655, WDR58 ENSG00000131652 THO complex 6 16 3024027-3027755 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA052953 Uncertain Supported Nucleoplasm
Nuclear speckles Renal cancer:4.40e-4 (unfavourable) Expressed in all Expressed in all skin: 29.3 THOC7 FLJ23445, fSAP24, NIF3L1BP1 ENSG00000163634 THO complex 7 3 63833870-63863903 Predicted intracellular proteins Evidence at protein level HPA044143 Approved Supported Nuclear speckles
Cytosol Expressed in all Expressed in all breast: 83.8 THOP1 ENSG00000172009 Thimet oligopeptidase 1 19 2785460-2815807 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB025497, HPA035262 Uncertain Supported Cytosol Endometrial cancer:2.35e-4 (favourable), Stomach cancer:5.90e-4 (favourable) Expressed in all Expressed in all testis: 36.2 THRA AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3 ENSG00000126351 Thyroid hormone receptor, alpha 17 40058290-40093867 Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009654, CAB023349 Uncertain Supported Cytosol Renal cancer:6.05e-8 (favourable), Lung cancer:1.84e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 239.6 THRAP3 TRAP150 ENSG00000054118 Thyroid hormone receptor associated protein 3 1 36224416-36305357 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012041, CAB017472, HPA063765 Supported Validated Nuclear speckles Stomach cancer:5.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 97.5 THTPA THTPASE ENSG00000259431 Thiamine triphosphatase 14 23555988-23560271 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028876 Approved Uncertain Nucleus
Nucleoli Renal cancer:1.70e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 32.8 THUMPD1 FLJ20274, Tan1 ENSG00000066654 THUMP domain containing 1 16 20733664-20742084 Predicted intracellular proteins Evidence at protein level HPA027851 Approved Approved Cytosol Renal cancer:8.52e-8 (favourable), Colorectal cancer:2.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 67.5 THUMPD3 DKFZP434F091 ENSG00000134077 THUMP domain containing 3 3 9362842-9386791 Predicted intracellular proteins Evidence at protein level HPA036170, HPA036171 Approved Approved Nucleoli
Cytosol Liver cancer:1.25e-7 (unfavourable), Renal cancer:1.03e-4 (favourable) Expressed in all Expressed in all testis: 107.0 THYN1 THY28 ENSG00000151500 Thymocyte nuclear protein 1 11 134248279-134253370 Predicted intracellular proteins Evidence at protein level HPA038732, HPA038733 Supported Supported Nucleus
Nucleoli fibrillar center
Cytosol Lung cancer:1.01e-5 (favourable) Expressed in all Expressed in all epididymis: 90.7 TIA1 ENSG00000116001 TIA1 cytotoxic granule-associated RNA binding protein 2 70209444-70248660 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA056961 Supported Nucleoplasm
Cytosol Renal cancer:8.05e-7 (unfavourable), Urothelial cancer:1.02e-5 (favourable), Lung cancer:6.79e-5 (favourable) Expressed in all Expressed in all endometrium: 112.3 TIAL1 TIAR ENSG00000151923 TIA1 cytotoxic granule-associated RNA binding protein-like 1 10 119571802-119597029 Predicted intracellular proteins Evidence at protein level HPA060962 Approved Nucleus
Vesicles Liver cancer:7.81e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 84.9 TICAM1 MGC35334, PRVTIRB, TICAM-1, TRIF ENSG00000127666 Toll-like receptor adaptor molecule 1 19 4815932-4831704 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA042460 Uncertain Approved Nucleus
Nucleoli
Plasma membrane Lung cancer:3.48e-4 (unfavourable), Endometrial cancer:4.81e-4 (favourable) Expressed in all Expressed in all esophagus: 22.1 TIFA MGC20791, T2BP, T6BP, TIFAA ENSG00000145365 TRAF-interacting protein with forkhead-associated domain 4 112274542-112285903 Predicted intracellular proteins Evidence at protein level HPA045889 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 38.1 TIGD1 EEYORE ENSG00000221944 Tigger transposable element derived 1 2 232547968-232550592 Predicted intracellular proteins Evidence at protein level HPA041717 Approved Supported Nucleus
Nucleoli
Nuclear bodies Renal cancer:4.41e-5 (unfavourable) Expressed in all Expressed in all testis: 18.1 TIMM10 TIM10, TIM10A ENSG00000134809 Translocase of inner mitochondrial membrane 10 homolog (yeast) 11 57528463-57530803 Predicted intracellular proteins Evidence at protein level HPA039946 Supported Validated Mitochondria Expressed in all Expressed in all epididymis: 52.0 TIMM10B FXC1, TIM10B, Tim9b ENSG00000132286 Translocase of inner mitochondrial membrane 10 homolog B (yeast) 11 6481447-6484679 Predicted intracellular proteins Evidence at protein level HPA052265 Approved Renal cancer:3.19e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 52.0 TIMM13 Tim13, TIMM13B ENSG00000099800 Translocase of inner mitochondrial membrane 13 homolog (yeast) 19 2425624-2427894 Predicted intracellular proteins Evidence at protein level HPA048985 Uncertain Supported Nucleoli fibrillar center
Mitochondria Renal cancer:3.88e-5 (favourable), Endometrial cancer:4.68e-5 (favourable), Pancreatic cancer:9.77e-4 (favourable) Expressed in all Expressed in all adrenal gland: 53.3 TIMM17A TIM17, TIM17A ENSG00000134375 Translocase of inner mitochondrial membrane 17 homolog A (yeast) 1 201955491-201970661 Cancer-related genes, Predicted membrane proteins Evidence at protein level HPA010083 Approved Supported Nucleoplasm
Mitochondria Breast cancer:1.98e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 62.9 TIMM17B DXS9822, JM3 ENSG00000126768 Translocase of inner mitochondrial membrane 17 homolog B (yeast) X 48893447-48898143 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029093 Approved Approved Microtubules
Mitochondria Cervical cancer:6.63e-4 (favourable), Urothelial cancer:7.88e-4 (favourable) Expressed in all Expressed in all fallopian tube: 43.4 TIMM21 C18orf55, HSPC154, TIM21 ENSG00000075336 Translocase of inner mitochondrial membrane 21 homolog (yeast) 18 74148511-74160530 Predicted membrane proteins Evidence at protein level HPA010587, HPA051543 Uncertain Approved Nucleoplasm Renal cancer:1.38e-9 (favourable), Liver cancer:9.22e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 25.7 TIMM23 TIM23 ENSG00000265354 Translocase of inner mitochondrial membrane 23 homolog (yeast) 10 45972449-46003734 Predicted membrane proteins Evidence at protein level HPA031408 Approved Supported Mitochondria Liver cancer:2.77e-5 (unfavourable), Ovarian cancer:6.79e-4 (favourable) Expressed in all Expressed in all testis: 141.6 TIMM44 TIM44 ENSG00000104980 Translocase of inner mitochondrial membrane 44 homolog (yeast) 19 7926718-7943920 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043052 Supported Validated Mitochondria Expressed in all Expressed in all heart muscle: 18.5 TIMM50 TIM50L ENSG00000105197 Translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 19 39480412-39493785 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048843, HPA056448 Supported Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 80.4 TIMM8B DDP2, FLJ21744, MGC102866, MGC117373, TIM8B ENSG00000150779 Translocase of inner mitochondrial membrane 8 homolog B (yeast) 11 112084800-112086798 Predicted intracellular proteins Evidence at protein level HPA041173 Supported Expressed in all Expressed in all adrenal gland: 39.5 TIMM9 TIM9A ENSG00000100575 Translocase of inner mitochondrial membrane 9 homolog (yeast) 14 58408494-58427614 Predicted intracellular proteins Evidence at protein level HPA002932 Approved Validated Mitochondria Ovarian cancer:6.39e-5 (favourable), Liver cancer:9.89e-5 (unfavourable), Breast cancer:8.04e-4 (favourable) Expressed in all Expressed in all thyroid gland: 48.2 TIMMDC1 C3orf1, FLJ22597 ENSG00000113845 Translocase of inner mitochondrial membrane domain containing 1 3 119498532-119525090 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA053214, HPA055846 Uncertain Validated Nucleus
Mitochondria Liver cancer:1.12e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 31.5 TIMP1 CLGI, EPO, TIMP ENSG00000102265 TIMP metallopeptidase inhibitor 1 X 47582313-47586789 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB022360, HPA053417 Approved Approved Golgi apparatus Renal cancer:2.90e-11 (unfavourable), Colorectal cancer:2.09e-4 (unfavourable) Expressed in all Expressed in all appendix: 2083.7 TIMP2 CSC-21K ENSG00000035862 TIMP metallopeptidase inhibitor 2 17 78852977-78925387 Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010203 Approved Expressed in all Expressed in all ovary: 1176.3 TIPARP DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1 ENSG00000163659 TCDD-inducible poly(ADP-ribose) polymerase 3 156673235-156706770 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA036796, HPA049230 Uncertain Uncertain Nucleoplasm
Microtubules
Microtubule organizing center Breast cancer:2.00e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 228.1 TIPRL dJ69E11.3, MGC3794, TIP41 ENSG00000143155 TOR signaling pathway regulator 1 168178933-168202114 Predicted intracellular proteins Evidence at protein level HPA027995, HPA054282 Approved Supported Vesicles
Cytosol Renal cancer:1.45e-8 (unfavourable), Liver cancer:1.60e-4 (unfavourable) Expressed in all Expressed in all endometrium: 38.5 TJAP1 PILT, TJP4 ENSG00000137221 Tight junction associated protein 1 (peripheral) 6 43477523-43506556 Predicted intracellular proteins Evidence at protein level HPA030164, HPA030165, HPA030166 Supported Approved Golgi apparatus Liver cancer:9.02e-6 (unfavourable), Renal cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all endometrium: 33.7 TJP2 DFNA51, X104, ZO-2, ZO2 ENSG00000119139 Tight junction protein 2 9 69121264-69255208 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001813, CAB009228 Supported Validated Plasma membrane
Cell Junctions
Cytosol Renal cancer:1.78e-14 (favourable) Expressed in all Expressed in all parathyroid gland: 136.2 TK2 SCA31 ENSG00000166548 Thymidine kinase 2, mitochondrial 16 66508003-66552544 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA041162 Uncertain Renal cancer:2.18e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 88.2 TKFC DAK, DKFZP586B1621, NET45 ENSG00000149476 Triokinase/FMN cyclase 11 61333210-61353295 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039486, HPA048186 Supported Approved Nucleus
Cytosol Endometrial cancer:1.32e-5 (favourable), Renal cancer:8.38e-5 (favourable) Expressed in all Expressed in all duodenum: 205.9 TKT ENSG00000163931 Transketolase 3 53224707-53256052 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA029480, HPA029481 Supported Validated Nucleoplasm Liver cancer:7.21e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 432.0 TLE1 ESG, ESG1, GRG1 ENSG00000196781 Transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 9 81583683-81689305 Predicted intracellular proteins Evidence at protein level CAB011482, HPA071396 Supported Supported Nucleoplasm Thyroid cancer:7.60e-4 (unfavourable), Renal cancer:8.07e-4 (favourable) Expressed in all Expressed in all endometrium: 52.1 TLE4 E(spI), ESG, GRG4 ENSG00000106829 Transducin-like enhancer of split 4 9 79571773-79726882 Predicted intracellular proteins Evidence at protein level HPA065357 Supported Nucleus Renal cancer:6.94e-4 (favourable) Expressed in all Expressed in all testis: 201.5 TLK1 KIAA0137, PKU-BETA ENSG00000198586 Tousled-like kinase 1 2 170990823-171231314 Enzymes, Predicted intracellular proteins Evidence at protein level HPA016043 Approved Validated Nucleus Expressed in all Expressed in all parathyroid gland: 40.0 TLK2 MGC44450, PKU-ALPHA ENSG00000146872 Tousled-like kinase 2 17 62458658-62615481 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level Liver cancer:9.40e-4 (unfavourable) Expressed in all Expressed in all testis: 104.1 TLN1 ILWEQ, TLN ENSG00000137076 Talin 1 9 35696948-35732395 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB002006, HPA004748 Supported Supported Plasma membrane
Focal adhesion sites
Microtubule organizing center
Cytosol Colorectal cancer:5.56e-4 (unfavourable), Renal cancer:7.21e-4 (favourable) Expressed in all Expressed in all smooth muscle: 202.0 TM2D1 BBP ENSG00000162604 TM2 domain containing 1 1 61681046-61725423 Predicted membrane proteins Evidence at protein level HPA046058, HPA055621 Approved Validated Nucleoplasm Liver cancer:2.02e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 67.8 TM2D2 BLP1 ENSG00000169490 TM2 domain containing 2 8 38988808-38996824 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA047152, HPA050547 Approved Approved Nucleoplasm
Vesicles
Plasma membrane Colorectal cancer:1.71e-4 (favourable), Breast cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all testis: 51.1 TM2D3 BLP2, FLJ22604 ENSG00000184277 TM2 domain containing 3 15 101621444-101652391 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA054064 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 97.5 TM4SF1 L6, M3S1 ENSG00000169908 Transmembrane 4 L six family member 1 3 149369022-149377865 Predicted membrane proteins Evidence at protein level CAB002760, HPA002823 Uncertain Urothelial cancer:3.43e-6 (unfavourable), Renal cancer:2.24e-4 (unfavourable), Pancreatic cancer:4.01e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 328.4 TM7SF2 ANG1, DHCR14A, NET47 ENSG00000149809 Transmembrane 7 superfamily member 2 11 65111845-65116384 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030691, HPA072704 Approved Supported Endoplasmic reticulum
Vesicles Renal cancer:8.49e-8 (favourable) Expressed in all Expressed in all adrenal gland: 161.3 TM7SF3 ENSG00000064115 Transmembrane 7 superfamily member 3 12 26973195-27014434 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA041097, HPA057640 Uncertain Approved Nucleus
Cytosol Renal cancer:1.32e-4 (favourable) Expressed in all Expressed in all kidney: 189.4 TM9SF1 HMP70, MP70 ENSG00000100926 Transmembrane 9 superfamily member 1 14 24189143-24195687 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA059249 Supported Approved Golgi apparatus Lung cancer:2.04e-4 (unfavourable), Cervical cancer:8.94e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 71.2 TM9SF2 P76 ENSG00000125304 Transmembrane 9 superfamily member 2 13 99501417-99564006 Predicted membrane proteins, Transporters Evidence at protein level HPA005657 Supported Renal cancer:5.21e-7 (favourable), Head and neck cancer:6.40e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 201.3 TM9SF3 SMBP ENSG00000077147 Transmembrane 9 superfamily member 3 10 96518109-96587452 Predicted membrane proteins Evidence at protein level HPA039609 Approved Approved Golgi apparatus
Vesicles Expressed in all Expressed in all stomach: 182.0 TM9SF4 dJ836N17.2, KIAA0255 ENSG00000101337 Transmembrane 9 superfamily protein member 4 20 32109506-32167258 Predicted membrane proteins, Transporters Evidence at protein level HPA064099 Approved Approved Mitochondria Endometrial cancer:6.37e-6 (unfavourable), Liver cancer:2.15e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 91.3 TMA16 C4orf43, FLJ11184 ENSG00000198498 Translation machinery associated 16 homolog 4 163494442-163520539 Predicted intracellular proteins Evidence at protein level HPA041571, HPA052688 Uncertain Validated Nucleoli Liver cancer:2.70e-5 (unfavourable), Lung cancer:4.40e-4 (unfavourable), Renal cancer:7.70e-4 (unfavourable) Expressed in all Expressed in all testis: 43.5 TMA7 CCDC72, HSPC016 ENSG00000232112 Translation machinery associated 7 homolog 3 48440257-48444208 Predicted intracellular proteins Evidence at protein level HPA047397 Approved Approved Nucleus
Nucleoli
Nuclear bodies Lung cancer:8.33e-4 (favourable) Expressed in all Expressed in all epididymis: 420.8 TMBIM1 LFG3, PP1201, RECS1 ENSG00000135926 Transmembrane BAX inhibitor motif containing 1 2 218274192-218292586 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA012093, HPA070824 Approved Supported Vesicles Renal cancer:3.38e-4 (favourable), Pancreatic cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all esophagus: 270.8 TMBIM4 CGI-119, GAAP, LFG4, S1R, ZPRO ENSG00000155957 Transmembrane BAX inhibitor motif containing 4 12 66135846-66170072 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA077642 Supported Golgi apparatus Expressed in all Expressed in all thyroid gland: 164.8 TMBIM4 ENSG00000282031 Transmembrane BAX inhibitor motif containing 4 12 66137960-66169896 Predicted membrane proteins Evidence at transcript level Expressed in all epididymis: 77.8 TMBIM6 BAXI1, BI-1, TEGT ENSG00000139644 Transmembrane BAX inhibitor motif containing 6 12 49707725-49764934 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA017378 Approved Renal cancer:1.00e-5 (favourable), Head and neck cancer:1.91e-4 (unfavourable), Breast cancer:3.54e-4 (unfavourable) Expressed in all Expressed in all kidney: 1179.3 TMC6 EVER1, EVIN1, LAK-4P ENSG00000141524 Transmembrane channel-like 6 17 78110458-78132407 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA051430 Uncertain Stomach cancer:1.82e-4 (favourable), Urothelial cancer:3.20e-4 (favourable) Expressed in all Expressed in all spleen: 84.5 TMCC1 KIAA0779 ENSG00000172765 Transmembrane and coiled-coil domain family 1 3 129647792-129893576 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA053894 Uncertain Renal cancer:1.77e-6 (unfavourable), Pancreatic cancer:1.87e-4 (unfavourable), Liver cancer:9.15e-4 (unfavourable) Expressed in all Expressed in all testis: 25.1 TMCO1 HP10122, TMCC4 ENSG00000143183 Transmembrane and coiled-coil domains 1 1 165724293-165827755 Disease related genes, Predicted membrane proteins Evidence at protein level HPA054768 Supported Endoplasmic reticulum Head and neck cancer:5.17e-7 (unfavourable), Renal cancer:1.25e-4 (unfavourable), Liver cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 157.3 TMCO3 C13orf11, FLJ20623 ENSG00000150403 Transmembrane and coiled-coil domains 3 13 113490995-113554590 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039561, HPA048126 Uncertain Approved Cytosol Liver cancer:1.14e-5 (unfavourable), Urothelial cancer:4.10e-4 (unfavourable), Cervical cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 49.2 TMED1 Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L ENSG00000099203 Transmembrane p24 trafficking protein 1 19 10832438-10836318 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA018507, HPA078574 Uncertain Supported Vesicles Renal cancer:8.66e-5 (favourable) Expressed in all Expressed in all thyroid gland: 47.6 TMED10 p23, P24(DELTA), p24d1, p24delta1, TMP21 ENSG00000170348 Transmembrane p24 trafficking protein 10 14 75131470-75176631 Predicted membrane proteins Evidence at protein level CAB034442, CAB037251, HPA047139, HPA050539 Supported Supported Golgi apparatus Thyroid cancer:8.67e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 243.4 TMED2 P24A, p24b1, p24beta1, RNP24 ENSG00000086598 Transmembrane p24 trafficking protein 2 12 123584531-123598577 Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA014060 Approved Supported Vesicles Renal cancer:2.35e-7 (unfavourable), Head and neck cancer:3.36e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 327.0 TMED4 HNLF, p24a3, p24alpha3 ENSG00000158604 Transmembrane p24 trafficking protein 4 7 44577894-44582287 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014650 Approved Renal cancer:1.37e-4 (favourable), Endometrial cancer:7.37e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 190.1 TMED5 CGI-100, p24g2, p24gamma2 ENSG00000117500 Transmembrane p24 trafficking protein 5 1 93149742-93180728 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050289 Approved Expressed in all Expressed in all kidney: 28.0 TMED7 CGI-109, FLJ90481, p24g3, p24gamma3 ENSG00000134970 Transmembrane p24 trafficking protein 7 5 115613508-115632992 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008960, CAB025883 Supported Expressed in all Expressed in all thyroid gland: 138.5 TMED9 HSGP25L2G, p24a2, p24alpha2 ENSG00000184840 Transmembrane p24 trafficking protein 9 5 177592158-177596124 Predicted membrane proteins Evidence at protein level HPA014650 Approved Renal cancer:5.88e-5 (unfavourable) Expressed in all Expressed in all placenta: 211.2 TMEM101 FLJ23987, MGC4251 ENSG00000091947 Transmembrane protein 101 17 44011188-44023946 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039739 Approved Nucleoplasm
Plasma membrane Renal cancer:4.10e-5 (favourable), Endometrial cancer:4.29e-4 (favourable), Liver cancer:7.10e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 156.9 TMEM104 FLJ00021, FLJ20255 ENSG00000109066 Transmembrane protein 104 17 74776483-74839779 Predicted membrane proteins, Transporters Evidence at protein level HPA044330 Approved Approved Nucleoplasm
Golgi apparatus Pancreatic cancer:1.97e-5 (favourable), Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.7 TMEM106B FLJ11273, MGC33727 ENSG00000106460 Transmembrane protein 106B 7 12211241-12243367 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA058342 Approved Supported Endosomes
Lysosomes Expressed in all Expressed in all thyroid gland: 64.7 TMEM106C MGC5576 ENSG00000134291 Transmembrane protein 106C 12 47963569-47968878 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047204 Supported Liver cancer:5.27e-8 (unfavourable), Renal cancer:4.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 165.9 TMEM109 MGC5508 ENSG00000110108 Transmembrane protein 109 11 60913874-60923443 Predicted membrane proteins, Transporters Evidence at protein level HPA011785 Approved Approved Nuclear membrane
Cytosol Urothelial cancer:2.68e-4 (unfavourable) Expressed in all Expressed in all endometrium: 94.2 TMEM110 MGC52022 ENSG00000213533 Transmembrane protein 110 3 52836219-52897596 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA051855 Uncertain Approved Cytosol Mixed Expressed in all fallopian tube: 20.8 TMEM115 PL6 ENSG00000126062 Transmembrane protein 115 3 50354749-50359610 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB006319, HPA015497 Supported Supported Golgi apparatus Renal cancer:1.04e-7 (favourable), Liver cancer:3.73e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 36.8 TMEM120A NET29, TMPIT ENSG00000189077 Transmembrane protein 120A 7 75986837-75994659 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all small intestine: 73.9 TMEM123 KCT3, PORIMIN ENSG00000152558 Transmembrane protein 123 11 102396332-102470384 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB026001 Approved Cytosol Pancreatic cancer:2.66e-4 (unfavourable), Melanoma:5.36e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 573.7 TMEM126A DKFZp586C1924, OPA7 ENSG00000171202 Transmembrane protein 126A 11 85647967-85656547 Disease related genes, Predicted membrane proteins Evidence at protein level HPA046648 Approved Approved Nucleus
Cytosol Liver cancer:8.60e-5 (unfavourable) Expressed in all Expressed in all testis: 66.9 TMEM126B HT007 ENSG00000171204 Transmembrane protein 126B 11 85628573-85636539 Predicted membrane proteins Evidence at protein level HPA014480, HPA019186 Uncertain Supported Mitochondria Expressed in all Expressed in all epididymis: 39.2 TMEM127 FLJ20507, FLJ22257 ENSG00000135956 Transmembrane protein 127 2 96248516-96265994 Disease related genes, Predicted membrane proteins Evidence at protein level Renal cancer:6.69e-5 (favourable), Liver cancer:6.59e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 110.4 TMEM128 MGC13159 ENSG00000132406 Transmembrane protein 128 4 4235542-4248212 Predicted membrane proteins Evidence at protein level HPA044809 Uncertain Expressed in all Expressed in all thyroid gland: 63.7 TMEM129 D4S2561E ENSG00000168936 Transmembrane protein 129, E3 ubiquitin protein ligase 4 1715952-1721358 Predicted membrane proteins Evidence at protein level HPA060920 Approved Vesicles Renal cancer:9.64e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 35.6 TMEM131 CC28, KIAA0257, PRO1048, RW1, YR-23 ENSG00000075568 Transmembrane protein 131 2 97756333-97995891 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017678, HPA017682 Approved Uncertain Vesicles
Intermediate filaments Expressed in all Expressed in all parathyroid gland: 46.7 TMEM134 FLJ21749 ENSG00000172663 Transmembrane protein 134 11 67461710-67469272 Predicted membrane proteins Evidence at protein level HPA043744 Approved Supported Cytosol Expressed in all Expressed in all skin: 38.4 TMEM135 FLJ22104 ENSG00000166575 Transmembrane protein 135 11 87037844-87323758 Predicted membrane proteins Evidence at protein level HPA056685, HPA069473 Uncertain Supported Vesicles Renal cancer:9.02e-4 (favourable) Expressed in all Expressed in all adipose tissue: 31.8 TMEM138 HSPC196, JBTS16 ENSG00000149483 Transmembrane protein 138 11 61362001-61369509 Disease related genes, Predicted membrane proteins Evidence at protein level HPA042373 Approved Approved Microtubules Renal cancer:4.12e-6 (unfavourable), Liver cancer:7.90e-4 (unfavourable) Expressed in all Expressed in all epididymis: 24.8 TMEM140 FLJ11000 ENSG00000146859 Transmembrane protein 140 7 135148072-135166215 Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all spleen: 40.1 TMEM141 MGC14141 ENSG00000244187 Transmembrane protein 141 9 136791355-136793257 Predicted membrane proteins Evidence at protein level HPA014615, HPA050244 Approved Supported Cell Junctions
Mitochondria Renal cancer:6.63e-4 (favourable) Expressed in all Expressed in all prostate: 214.3 TMEM147 MGC1936, NIFIE14 ENSG00000105677 Transmembrane protein 147 19 35545595-35547526 Predicted membrane proteins Evidence at protein level HPA067837 Uncertain Golgi apparatus
Actin filaments
Cytosol Liver cancer:4.98e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 120.1 TMEM14A C6orf73, PTD011 ENSG00000096092 Transmembrane protein 14A 6 52671109-52686588 Predicted membrane proteins Evidence at protein level HPA072536 Approved Nucleoplasm
Endoplasmic reticulum Expressed in all Expressed in all cerebral cortex: 88.4 TMEM14B MGC1223 ENSG00000137210 Transmembrane protein 14B 6 10747759-10852753 Predicted membrane proteins Evidence at protein level Liver cancer:9.35e-5 (unfavourable), Endometrial cancer:6.51e-4 (unfavourable), Ovarian cancer:7.41e-4 (favourable) Expressed in all Expressed in all thyroid gland: 204.2 TMEM14C bA421M1.6, C6orf53, HSPC194, NET26 ENSG00000111843 Transmembrane protein 14C 6 10722915-10731129 Predicted membrane proteins Evidence at protein level Liver cancer:3.66e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 138.2 TMEM159 promethin ENSG00000011638 Transmembrane protein 159 16 21158377-21180616 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018033, HPA063509 Approved Approved Vesicles Renal cancer:8.11e-5 (favourable), Pancreatic cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all skin: 90.6 TMEM161A FLJ20422, FLJ39645 ENSG00000064545 Transmembrane protein 161A 19 19119169-19138513 Predicted membrane proteins Evidence at protein level HPA043365 Approved Approved Cytosol Stomach cancer:2.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 20.9 TMEM161B MGC33214 ENSG00000164180 Transmembrane protein 161B 5 88189633-88269476 Predicted membrane proteins Evidence at protein level HPA044562 Uncertain Expressed in all Expressed in all parathyroid gland: 58.9 TMEM164 FLJ22679, RP13-360B22.2 ENSG00000157600 Transmembrane protein 164 X 110002631-110182734 Predicted membrane proteins Evidence at protein level HPA038784 Approved Approved Vesicles
Cell Junctions Liver cancer:8.17e-6 (unfavourable), Stomach cancer:3.14e-4 (favourable) Expressed in all Expressed in all lung: 26.7 TMEM165 GDT1, TMPT27, TPARL ENSG00000134851 Transmembrane protein 165 4 55395957-55453397 Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA038299 Supported Supported Golgi apparatus
Vesicles Renal cancer:1.18e-8 (unfavourable), Liver cancer:2.08e-5 (unfavourable) Expressed in all Expressed in all placenta: 86.4 TMEM167A FLJ30508, MGC23909, TMEM167 ENSG00000174695 Transmembrane protein 167A 5 83052846-83077863 Predicted membrane proteins Evidence at protein level Expressed in all Expressed in all adrenal gland: 62.2 TMEM167B AD-020, C1orf119, FLJ90710 ENSG00000215717 Transmembrane protein 167B 1 109089803-109096934 Predicted membrane proteins Evidence at transcript level Endometrial cancer:8.86e-4 (favourable) Expressed in all Expressed in all thyroid gland: 49.3 TMEM168 DKFZp564C012, FLJ13576 ENSG00000146802 Transmembrane protein 168 7 112762382-112790592 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA020389 Approved Lung cancer:4.07e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 43.5 TMEM170A FLJ37611, TMEM170 ENSG00000166822 Transmembrane protein 170A 16 75443054-75465497 Predicted membrane proteins Evidence at transcript level HPA055071 Uncertain Renal cancer:2.36e-9 (favourable) Expressed in all Expressed in all testis: 32.6 TMEM173 FLJ38577, NET23 ENSG00000184584 Transmembrane protein 173 5 139475534-139482935 Disease related genes, Predicted membrane proteins Evidence at protein level HPA038116, HPA038534 Supported Supported Cytosol Renal cancer:3.59e-8 (unfavourable) Expressed in all Expressed in all lung: 70.2 TMEM175 MGC4618 ENSG00000127419 Transmembrane protein 175 4 932387-958656 Predicted membrane proteins, Transporters Evidence at protein level HPA057160 Approved Approved Nucleus
Nuclear membrane Pancreatic cancer:9.85e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 20.8 TMEM176A HCA112, MS4B1 ENSG00000002933 Transmembrane protein 176A 7 150800403-150805120 Predicted membrane proteins Evidence at protein level HPA008770 Approved Approved Mitochondria Expressed in all Expressed in all liver: 579.4 TMEM176B LR8, MS4B2 ENSG00000106565 Transmembrane protein 176B 7 150791285-150801360 Predicted membrane proteins Evidence at protein level HPA047509 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane Expressed in all Expressed in all liver: 842.9 TMEM179B ENSG00000185475 Transmembrane protein 179B 11 62787415-62790405 Predicted membrane proteins Evidence at protein level HPA016585, HPA062068 Validated Nuclear speckles Expressed in all Expressed in all epididymis: 86.2 TMEM18 DKFZp434C1714 ENSG00000151353 Transmembrane protein 18 2 667335-677439 Predicted membrane proteins Evidence at protein level HPA040233 Approved Approved Mitochondria Melanoma:3.21e-4 (unfavourable) Expressed in all Expressed in all ovary: 43.9 TMEM181 GPR178, KIAA1423 ENSG00000146433 Transmembrane protein 181 6 158536436-158635428 Predicted membrane proteins Evidence at protein level HPA040189 Approved Approved Golgi apparatus
Vesicles Ovarian cancer:1.09e-4 (unfavourable), Cervical cancer:7.26e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 41.5 TMEM183A C1orf37 ENSG00000163444 Transmembrane protein 183A 1 203007386-203024848 Predicted membrane proteins Evidence at protein level HPA072607 Approved Nucleus
Plasma membrane
Cell Junctions Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all testis: 58.5 TMEM184B C22orf5, DKFZP586A1024, FM08, HS5O6A ENSG00000198792 Transmembrane protein 184B 22 38219291-38273034 Predicted membrane proteins, Transporters Evidence at protein level HPA024076 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:5.94e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 57.5 TMEM185A CXorf13, FAM11A, FRAXF ENSG00000269556 Transmembrane protein 185A X 149596556-149631912 Predicted membrane proteins Evidence at protein level HPA048295, HPA071744 Uncertain Approved Endoplasmic reticulum Expressed in all Expressed in all ovary: 36.3 TMEM185B FAM11B, FLJ20979 ENSG00000226479 Transmembrane protein 185B 2 120221278-120223408 Predicted membrane proteins Evidence at protein level HPA048295, HPA071744 Uncertain Approved Endoplasmic reticulum Liver cancer:5.71e-7 (unfavourable), Endometrial cancer:4.96e-6 (unfavourable), Colorectal cancer:5.44e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 61.4 TMEM186 C16orf51, DKFZP564K2062 ENSG00000184857 Transmembrane protein 186 16 8780384-8797648 Predicted membrane proteins Evidence at protein level HPA018226, HPA063559 Uncertain Approved Cell Junctions Renal cancer:1.93e-8 (favourable) Expressed in all Expressed in all parathyroid gland: 22.5 TMEM187 CXorf12, DXS9878E, ITBA1 ENSG00000177854 Transmembrane protein 187 X 153972327-153983195 Predicted membrane proteins Evidence at transcript level HPA038134 Uncertain Approved Nucleoli
Cytosol Renal cancer:9.14e-8 (favourable) Expressed in all Expressed in all fallopian tube: 11.2 TMEM189 Kua ENSG00000240849 Transmembrane protein 189 20 50118254-50153734 Predicted membrane proteins Evidence at protein level HPA059549 Approved Supported Endoplasmic reticulum Renal cancer:5.79e-11 (unfavourable), Endometrial cancer:7.51e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 31.1 TMEM19 FLJ10936 ENSG00000139291 Transmembrane protein 19 12 71686087-71705046 Predicted membrane proteins Evidence at protein level HPA016830 Approved Expressed in all Expressed in all kidney: 40.5 TMEM192 FLJ38482 ENSG00000170088 Transmembrane protein 192 4 165070608-165208549 Predicted membrane proteins, Transporters Evidence at protein level HPA014717, HPA024110 Supported Validated Nucleoplasm
Endosomes
Lysosomes Renal cancer:2.33e-14 (favourable), Breast cancer:9.52e-4 (unfavourable) Expressed in all Expressed in all kidney: 50.6 TMEM199 C17orf32, MGC45714 ENSG00000244045 Transmembrane protein 199 17 28357581-28363683 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA027051 Uncertain Liver cancer:1.54e-4 (unfavourable), Endometrial cancer:5.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 19.1 TMEM2 ENSG00000135048 Transmembrane protein 2 9 71683366-71816690 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044889 Approved Approved Vesicles
Cytosol Renal cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all placenta: 93.9 TMEM203 HBEBP1, MGC14327 ENSG00000187713 Transmembrane protein 203 9 137204082-137205638 Predicted membrane proteins Evidence at protein level Pancreatic cancer:4.78e-6 (favourable), Renal cancer:1.50e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 39.9 TMEM205 MBC3205, UNQ501 ENSG00000105518 Transmembrane protein 205 19 11342776-11346518 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA041504 Approved Approved Nucleoplasm
Nuclear membrane
Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 253.1 TMEM208 HSPC171 ENSG00000168701 Transmembrane protein 208 16 67227103-67229278 Predicted membrane proteins, Transporters Evidence at protein level HPA041868, HPA041949 Supported Head and neck cancer:9.63e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 88.4 TMEM209 FLJ14803, NET31 ENSG00000146842 Transmembrane protein 209 7 130164715-130207770 Predicted membrane proteins Evidence at protein level HPA031678 Uncertain Approved Nuclear membrane
Nuclear speckles
Vesicles Expressed in all Expressed in all testis: 27.7 TMEM214 FLJ20254 ENSG00000119777 Transmembrane protein 214 2 27032910-27041695 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034551 Supported Endoplasmic reticulum
Golgi apparatus
Cytosol Renal cancer:2.39e-10 (unfavourable), Liver cancer:4.96e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 89.8 TMEM218 ENSG00000150433 Transmembrane protein 218 11 125096545-125111763 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA038489 Uncertain Approved Plasma membrane
Cytosol Liver cancer:1.93e-5 (unfavourable), Stomach cancer:5.50e-4 (favourable) Expressed in all Expressed in all fallopian tube: 21.7 TMEM219 ENSG00000149932 Transmembrane protein 219 16 29940885-29973052 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059185 Approved Endometrial cancer:5.79e-4 (favourable) Expressed in all Expressed in all fallopian tube: 196.0 TMEM220 ENSG00000187824 Transmembrane protein 220 17 10699015-10730316 Predicted membrane proteins Evidence at protein level Liver cancer:2.23e-5 (favourable), Pancreatic cancer:1.72e-4 (favourable), Glioma:9.39e-4 (unfavourable) Expressed in all Expressed in all liver: 53.9 TMEM222 C1orf160, DKFZP564D0478 ENSG00000186501 Transmembrane protein 222 1 27322145-27336400 Predicted membrane proteins Evidence at protein level HPA016579, HPA059374 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all fallopian tube: 47.4 TMEM223 MGC3196 ENSG00000168569 Transmembrane protein 223 11 62771629-62792021 Predicted membrane proteins Evidence at protein level HPA014504 Approved Approved Nucleus
Nuclear membrane
Mitochondria Expressed in all Expressed in all prostate: 16.9 TMEM230 C20orf30, HSPC274 ENSG00000089063 Transmembrane protein 230 20 5068232-5113103 Predicted membrane proteins Evidence at protein level HPA009078, HPA061421 Uncertain Validated Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 226.3 TMEM242 BM033, C6orf35 ENSG00000215712 Transmembrane protein 242 6 157289386-157323601 Predicted membrane proteins Evidence at protein level HPA025764 Approved Expressed in all Expressed in all cerebral cortex: 17.0 TMEM243 C7orf23, MGC4175, MM-TRAG ENSG00000135185 Transmembrane protein 243, mitochondrial 7 87196160-87220587 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014918 Uncertain Lung cancer:5.45e-4 (favourable), Melanoma:6.84e-4 (unfavourable), Urothelial cancer:9.13e-4 (favourable) Expressed in all Expressed in all thyroid gland: 103.3 TMEM245 C9orf5, CG-2 ENSG00000106771 Transmembrane protein 245 9 109015152-109119945 Predicted membrane proteins Evidence at protein level HPA023892 Approved Approved Plasma membrane
Cytosol Renal cancer:4.46e-9 (favourable) Expressed in all Expressed in all thyroid gland: 123.5 TMEM248 C7orf42, FLJ10099, FLJ13090 ENSG00000106609 Transmembrane protein 248 7 66921225-66958551 Predicted membrane proteins Evidence at protein level HPA016495 Uncertain Approved Vesicles Expressed in all Expressed in all parathyroid gland: 92.0 TMEM25 FLJ14399 ENSG00000149582 Transmembrane protein 25 11 118531041-118547280 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA012163, HPA051562 Approved Approved Golgi apparatus
Vesicles Renal cancer:0.00e+0 (favourable) Expressed in all Expressed in all duodenum: 48.3 TMEM251 C14orf109, DKFZP564F1123 ENSG00000153485 Transmembrane protein 251 14 93184951-93187089 Predicted membrane proteins Evidence at transcript level HPA048559 Uncertain Approved Golgi apparatus
Cell Junctions Liver cancer:6.14e-7 (unfavourable), Renal cancer:1.10e-4 (favourable) Expressed in all Expressed in all prostate: 27.9 TMEM254 bA369J21.6, C10orf57, FLJ13263 ENSG00000133678 Transmembrane protein 254 10 80078646-80092557 Predicted membrane proteins Evidence at protein level HPA029105 Approved Nucleoplasm
Plasma membrane Expressed in all Expressed in all skin: 85.9 TMEM256 C17orf61, MGC40107 ENSG00000205544 Transmembrane protein 256 17 7402975-7404137 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA062732 Approved Vesicles Renal cancer:9.36e-4 (unfavourable) Expressed in all Expressed in all duodenum: 140.8 TMEM256-PLSCR3 ENSG00000187838 TMEM256-PLSCR3 readthrough (NMD candidate) 17 7389727-7394843 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048387, HPA068609 Supported Supported Mitochondria Mixed Expressed in all smooth muscle: 38.5 TMEM258 C11orf10 ENSG00000134825 Transmembrane protein 258 11 61768501-61792802 Predicted membrane proteins Evidence at protein level HPA044602 Approved Approved Plasma membrane
Cytosol Ovarian cancer:4.37e-4 (favourable) Expressed in all Expressed in all epididymis: 429.6 TMEM259 ASBABP1, C19orf6, MBRL, MGC4022 ENSG00000182087 Transmembrane protein 259 19 1009648-1021179 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA042669, HPA054801 Approved Approved Nuclear speckles
Endoplasmic reticulum Stomach cancer:8.92e-6 (favourable), Endometrial cancer:1.01e-4 (favourable) Expressed in all Expressed in all spleen: 132.3 TMEM261 C9orf123, MGC4730 ENSG00000137038 Transmembrane protein 261 9 7796490-7888380 Predicted membrane proteins Evidence at protein level HPA014585 Approved Renal cancer:1.96e-11 (favourable), Endometrial cancer:4.15e-4 (favourable) Expressed in all Expressed in all thyroid gland: 17.3 TMEM263 C12orf23, MGC17943 ENSG00000151135 Transmembrane protein 263 12 106955719-106978778 Predicted intracellular proteins Evidence at protein level HPA042339 Uncertain Thyroid cancer:1.83e-4 (unfavourable), Liver cancer:7.84e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 63.4 TMEM30A C6orf67, CDC50A, FLJ10856 ENSG00000112697 Transmembrane protein 30A 6 75252924-75284968 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014561 Approved Supported Mitochondria Expressed in all Expressed in all cerebral cortex: 167.9 TMEM33 FLJ10525 ENSG00000109133 Transmembrane protein 33 4 41935120-41960572 Predicted membrane proteins Evidence at protein level Renal cancer:1.35e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.8 TMEM38B bA219P18.1, C9orf87, D4Ertd89e, FLJ10493, TRIC-B ENSG00000095209 Transmembrane protein 38B 9 105694544-105776612 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018465 Uncertain Renal cancer:7.96e-4 (favourable) Expressed in all Expressed in all testis: 51.9 TMEM39A FLJ10902 ENSG00000176142 Transmembrane protein 39A 3 119429500-119468830 Predicted membrane proteins Evidence at protein level HPA039140 Approved Approved Nucleoplasm
Vesicles Renal cancer:1.00e-5 (unfavourable), Liver cancer:3.26e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 32.9 TMEM41A MGC15397 ENSG00000163900 Transmembrane protein 41A 3 185476496-185499057 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059101, HPA059790 Approved Approved Nucleoplasm
Golgi apparatus
Cytosol Endometrial cancer:6.70e-6 (unfavourable), Liver cancer:1.04e-4 (unfavourable), Pancreatic cancer:4.72e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 28.3 TMEM42 MGC29956 ENSG00000169964 Transmembrane protein 42 3 44861869-44865670 Predicted membrane proteins Evidence at transcript level HPA052569 Uncertain Renal cancer:1.10e-5 (favourable), Breast cancer:5.23e-4 (favourable) Expressed in all Expressed in all epididymis: 12.5 TMEM43 ARVD5, DKFZp586G1919, LUMA, MGC3222 ENSG00000170876 Transmembrane protein 43 3 14124940-14143679 Disease related genes, Predicted membrane proteins Evidence at protein level HPA019198 Approved Pancreatic cancer:4.38e-4 (unfavourable) Expressed in all Expressed in all skin: 124.7 TMEM5 HP10481 ENSG00000118600 Transmembrane protein 5 12 63779803-63809558 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA064014 Approved Nucleoplasm
Golgi apparatus Liver cancer:5.24e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.1 TMEM50A SMP1 ENSG00000183726 Transmembrane protein 50A 1 25337917-25362361 Predicted membrane proteins Evidence at protein level HPA065192 Approved Plasma membrane
Actin filaments
Cytosol Endometrial cancer:8.64e-5 (favourable), Liver cancer:3.34e-4 (unfavourable) Expressed in all Expressed in all prostate: 71.1 TMEM50B C21orf4 ENSG00000142188 Transmembrane protein 50B 21 33432485-33480011 Predicted membrane proteins Evidence at protein level CAB034199, HPA068995 Approved Approved Nucleoli fibrillar center Head and neck cancer:3.00e-4 (favourable), Lung cancer:3.33e-4 (favourable) Expressed in all Expressed in all thyroid gland: 74.3 TMEM55B C14orf9, MGC26684 ENSG00000165782 Transmembrane protein 55B 14 20457719-20461612 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA048528 Approved Renal cancer:1.01e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 41.2 TMEM57 FLJ10747 ENSG00000204178 Transmembrane protein 57 1 25430858-25500209 Predicted membrane proteins, Transporters Evidence at protein level HPA019680 Approved Cytosol Renal cancer:7.13e-4 (favourable) Expressed in all Expressed in all testis: 36.0 TMEM59 C1orf8, HSPC001 ENSG00000116209 Transmembrane protein 59 1 54026681-54053504 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Expressed in all Expressed in all fallopian tube: 642.0 TMEM60 C7orf35, DC32 ENSG00000135211 Transmembrane protein 60 7 77793728-77798580 Predicted membrane proteins Evidence at transcript level HPA062625 Approved Breast cancer:3.09e-4 (favourable), Glioma:8.70e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 55.3 TMEM62 FLJ23375 ENSG00000137842 Transmembrane protein 62 15 43123279-43185146 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044461, HPA062359 Approved Approved Nucleus
Nucleoli fibrillar center
Nuclear bodies
Cytoplasmic bodies Endometrial cancer:9.72e-7 (favourable) Expressed in all Expressed in all breast: 27.2 TMEM63A KIAA0792 ENSG00000196187 Transmembrane protein 63A 1 225845536-225882369 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066504, HPA066936, HPA068918 Validated Vesicles
Microtubule organizing center Endometrial cancer:8.79e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 77.4 TMEM63B C6orf110, dJ421H19.2, DKFZp434P0531 ENSG00000137216 Transmembrane protein 63B 6 44126914-44155519 Predicted membrane proteins, Transporters Evidence at protein level HPA029249, HPA029250, HPA029251 Uncertain Validated Plasma membrane
Actin filaments Expressed in all Expressed in all lung: 59.2 TMEM64 DKFZp762C1112 ENSG00000180694 Transmembrane protein 64 8 90621995-90791632 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at transcript level CAB034221 Uncertain Expressed in all Expressed in all epididymis: 173.0 TMEM68 FLJ32370 ENSG00000167904 Transmembrane protein 68 8 55696424-55773407 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA018216, HPA019173 Uncertain Approved Vesicles Expressed in all Expressed in all fallopian tube: 36.6 TMEM69 C1orf154, FLJ21029 ENSG00000159596 Transmembrane protein 69 1 45687214-45694443 Predicted membrane proteins Evidence at transcript level HPA026993 Approved Approved Nucleoplasm Liver cancer:3.66e-8 (unfavourable), Breast cancer:2.24e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.9 TMEM70 FLJ20533 ENSG00000175606 Transmembrane protein 70 8 73972437-73982783 Disease related genes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA023187, CAB034226 Uncertain Supported Nucleoplasm
Mitochondria Expressed in all Expressed in all skeletal muscle: 30.2 TMEM80 FLJ38216 ENSG00000177042 Transmembrane protein 80 11 695428-705028 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA059592, HPA067046 Uncertain Approved Golgi apparatus Renal cancer:2.47e-4 (favourable) Expressed in all Expressed in all thyroid gland: 43.4 TMEM87A DKFZP564G2022 ENSG00000103978 Transmembrane protein 87A 15 42210452-42273663 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA018104, HPA018189 Supported Supported Golgi apparatus Expressed in all Expressed in all prostate: 122.4 TMEM8A M83, TMEM6, TMEM8 ENSG00000129925 Transmembrane protein 8A 16 370773-387113 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051281, HPA064673 Approved Supported Nucleoplasm
Cytokinetic bridge Renal cancer:1.29e-5 (favourable) Expressed in all Expressed in all testis: 57.6 TMEM8B C9orf127, NAG-5, NGX6 ENSG00000137103 Transmembrane protein 8B 9 35814451-35854847 Predicted membrane proteins Evidence at protein level HPA052130, HPA062701 Approved Approved Vesicles Renal cancer:1.89e-15 (favourable), Pancreatic cancer:3.14e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.7 TMEM9 TMEM9A ENSG00000116857 Transmembrane protein 9 1 201134772-201171574 Predicted membrane proteins Evidence at protein level Head and neck cancer:3.93e-4 (unfavourable), Cervical cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 122.6 TMEM91 FLJ27310, IFITMD6 ENSG00000142046 Transmembrane protein 91 19 41350911-41384083 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA053240 Uncertain Renal cancer:3.52e-7 (unfavourable), Pancreatic cancer:3.54e-5 (favourable) Expressed in all Expressed in all skin: 31.0 TMEM94 KIAA0195 ENSG00000177728 Transmembrane protein 94 17 75441159-75500090 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA008423, HPA050660 Approved Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:2.26e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 54.3 TMEM97 MAC30 ENSG00000109084 Transmembrane protein 97 17 28319095-28328685 Predicted membrane proteins Evidence at protein level HPA044795 Approved Approved Nuclear membrane
Plasma membrane
Cytosol Renal cancer:1.24e-4 (unfavourable) Expressed in all Expressed in all testis: 109.7 TMEM98 DKFZP564K1964 ENSG00000006042 Transmembrane protein 98 17 32927910-32945106 Disease related genes, Predicted membrane proteins Evidence at protein level HPA040473, HPA053385 Uncertain Supported Nucleoplasm Renal cancer:3.85e-4 (favourable), Lung cancer:7.10e-4 (favourable), Liver cancer:8.14e-4 (unfavourable) Expressed in all Expressed in all ovary: 237.4 TMEM9B C11orf15 ENSG00000175348 TMEM9 domain family, member B 11 8947294-8965011 Predicted membrane proteins Evidence at protein level HPA037784 Uncertain Renal cancer:4.26e-5 (favourable) Expressed in all Expressed in all thyroid gland: 129.2 TMF1 ARA160, TMF ENSG00000144747 TATA element modulatory factor 1 3 69019827-69052303 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008729 Approved Supported Golgi apparatus Expressed in all Expressed in all testis: 59.3 TMLHE BBOX2, FLJ10727, TMLH, XAP130 ENSG00000185973 Trimethyllysine hydroxylase, epsilon X 155490115-155669944 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA034589, HPA040331 Approved Supported Mitochondria Renal cancer:3.68e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 30.8 TMOD3 UTMOD ENSG00000138594 Tropomodulin 3 (ubiquitous) 15 51829628-51947295 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001849 Approved Approved Actin filaments
Cytosol Pancreatic cancer:3.38e-5 (unfavourable), Cervical cancer:3.25e-4 (unfavourable), Lung cancer:6.25e-4 (unfavourable) Expressed in all Expressed in all esophagus: 86.7 TMPO LAP2, LEMD4, TP ENSG00000120802 Thymopoietin 12 98515512-98550379 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA008150, CAB009847 Supported Validated Nuclear membrane Renal cancer:9.34e-4 (unfavourable) Expressed in all Expressed in all lymph node: 92.4 TMSB10 TB10 ENSG00000034510 Thymosin beta 10 2 84905625-84906675 Plasma proteins, Predicted intracellular proteins Evidence at protein level Renal cancer:8.49e-7 (unfavourable), Thyroid cancer:4.97e-5 (favourable) Expressed in all Expressed in all epididymis: 3641.5 TMSB4X TB4X, TMSB4 ENSG00000205542 Thymosin beta 4, X-linked X 12975108-12977227 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB033806 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:6.20e-4 (unfavourable) Expressed in all Expressed in all lymph node: 11737.0 TMTC4 FLJ14624, FLJ22153 ENSG00000125247 Transmembrane and tetratricopeptide repeat containing 4 13 100603927-100675093 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016489 Uncertain Approved Vesicles Expressed in all Expressed in all cerebral cortex: 26.5 TMUB1 C7orf21, SB144 ENSG00000164897 Transmembrane and ubiquitin-like domain containing 1 7 151081080-151083546 Predicted membrane proteins, Predicted secreted proteins, Transporters Evidence at protein level HPA029429 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all small intestine: 53.3 TMUB2 MGC3123 ENSG00000168591 Transmembrane and ubiquitin-like domain containing 2 17 44186970-44191731 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA043137 Approved Approved Vesicles
Cytosol Expressed in all Expressed in all testis: 48.5 TMX1 PDIA11, TMX, TXNDC, TXNDC1 ENSG00000139921 Thioredoxin-related transmembrane protein 1 14 51240162-51257546 Predicted membrane proteins Evidence at protein level HPA003085 Approved Supported Nucleoli
Endoplasmic reticulum Liver cancer:1.29e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 19.8 TMX2 PDIA12, TXNDC14 ENSG00000213593 Thioredoxin-related transmembrane protein 2 11 57712600-57740973 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA040282, HPA063763 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.55e-5 (favourable), Urothelial cancer:3.37e-4 (unfavourable), Head and neck cancer:3.64e-4 (unfavourable), Liver cancer:4.11e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 129.2 TMX3 FLJ20793, KIAA1830, PDIA13, TXNDC10 ENSG00000166479 Thioredoxin-related transmembrane protein 3 18 68673688-68715298 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA014157 Uncertain Renal cancer:2.87e-4 (unfavourable) Expressed in all Expressed in all appendix: 32.3 TMX4 DJ971N18.2, KIAA1162, PDIA14, TXNDC13 ENSG00000125827 Thioredoxin-related transmembrane protein 4 20 7977348-8019829 Predicted membrane proteins Evidence at protein level HPA000399, HPA015752 Supported Supported Nuclear membrane Renal cancer:2.60e-5 (favourable) Expressed in all Expressed in all testis: 117.9 TNFAIP1 B12, B61, BTBD34, EDP1, MGC2317 ENSG00000109079 Tumor necrosis factor, alpha-induced protein 1 (endothelial) 17 28335602-28347009 Predicted intracellular proteins Evidence at protein level HPA013333, HPA014641 Uncertain Validated Nucleoli Endometrial cancer:7.48e-5 (unfavourable) Expressed in all Expressed in all spleen: 70.2 TNFAIP2 B94, EXOC3L3 ENSG00000185215 Tumor necrosis factor, alpha-induced protein 2 14 103123442-103137439 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB004598, HPA030624 Supported Approved Nucleus
Nuclear membrane
Golgi apparatus
Cytosol Stomach cancer:2.79e-5 (favourable), Urothelial cancer:7.17e-5 (favourable), Renal cancer:4.10e-4 (unfavourable) Expressed in all Expressed in all urinary bladder: 211.4 TNFAIP3 A20, OTUD7C ENSG00000118503 Tumor necrosis factor, alpha-induced protein 3 6 137867188-137883312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002116 Approved Approved Centrosome
Cytosol Renal cancer:6.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 345.8 TNFAIP8 GG2-1, MDC-3.13, SCC-S2 ENSG00000145779 Tumor necrosis factor, alpha-induced protein 8 5 119268692-119399688 Predicted intracellular proteins Evidence at protein level HPA054434, HPA057089 Uncertain Supported Nucleoplasm Breast cancer:2.45e-4 (favourable) Expressed in all Expressed in all lymph node: 136.2 TNFRSF10B CD262, DR5, KILLER, TRAIL-R2, TRICK2A, TRICKB ENSG00000120889 Tumor necrosis factor receptor superfamily, member 10b 8 23020133-23069179 Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA023625 Approved Renal cancer:1.76e-4 (unfavourable) Expressed in all Expressed in all gallbladder: 33.4 TNFRSF12A CD266, FN14, TweakR ENSG00000006327 Tumor necrosis factor receptor superfamily, member 12A 16 3018445-3022383 Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA007853 Approved Approved Plasma membrane
Cytosol Head and neck cancer:5.50e-4 (unfavourable), Renal cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 195.6 TNFRSF14 ATAR, CD270, HVEA, HVEM, LIGHTR, TR2 ENSG00000157873 Tumor necrosis factor receptor superfamily, member 14 1 2555639-2565382 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA006404, CAB026150, CAB030007 Approved Approved Cytosol
Rods & Rings Urothelial cancer:7.79e-6 (favourable), Endometrial cancer:8.01e-6 (favourable), Breast cancer:4.39e-5 (favourable) Expressed in all Expressed in all duodenum: 46.7 TNFRSF1A CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60 ENSG00000067182 Tumor necrosis factor receptor superfamily, member 1A 12 6328757-6342114 Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA004102, CAB010309 Approved Renal cancer:2.70e-7 (unfavourable), Head and neck cancer:3.68e-4 (unfavourable), Endometrial cancer:8.22e-4 (favourable) Expressed in all Expressed in all gallbladder: 140.8 TNFRSF21 CD358, DR6 ENSG00000146072 Tumor necrosis factor receptor superfamily, member 21 6 47231532-47309905 CD markers, Plasma proteins, Predicted membrane proteins Evidence at protein level HPA006746, CAB009805 Approved Renal cancer:7.23e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 103.4 TNFSF10 Apo-2L, CD253, TL2, TRAIL ENSG00000121858 Tumor necrosis factor (ligand) superfamily, member 10 3 172505508-172523507 Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054938 Uncertain Approved Microtubules Pancreatic cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all lung: 260.2 TNFSF13 APRIL, CD256 ENSG00000161955 Tumor necrosis factor (ligand) superfamily, member 13 17 7558292-7561608 Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004863 Uncertain Renal cancer:1.30e-9 (favourable), Glioma:8.28e-4 (unfavourable) Expressed in all Expressed in all lung: 150.0 TNIP1 ABIN-1, KIAA0113, NAF1, VAN ENSG00000145901 TNFAIP3 interacting protein 1 5 151029945-151093577 Predicted intracellular proteins Evidence at protein level HPA037893, HPA037894, HPA071950 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:6.86e-5 (favourable), Breast cancer:5.69e-4 (favourable) Expressed in all Expressed in all adipose tissue: 132.2 TNIP2 ABIN-2, FLIP1, KLIP, MGC4289 ENSG00000168884 TNFAIP3 interacting protein 2 4 2741648-2756376 Predicted intracellular proteins Evidence at protein level CAB020818, HPA049886, HPA063197 Supported Validated Nucleoplasm
Cytosol Renal cancer:2.94e-5 (unfavourable), Endometrial cancer:1.13e-4 (favourable), Lung cancer:5.73e-4 (unfavourable) Expressed in all Expressed in all appendix: 22.2 TNK2 ACK, ACK1, p21cdc42Hs ENSG00000061938 Tyrosine kinase, non-receptor, 2 3 195863364-195911945 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041954 Approved Approved Cytosol Urothelial cancer:1.00e-4 (favourable), Renal cancer:1.30e-4 (unfavourable), Endometrial cancer:8.96e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 109.8 TNKS PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1 ENSG00000173273 Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 8 9555914-9782346 Enzymes, Predicted intracellular proteins, Transporters Evidence at protein level HPA025690 Approved Approved Nucleoplasm
Nuclear membrane Expressed in all Expressed in all testis: 52.7 TNKS1BP1 FLJ45975, KIAA1741, TAB182 ENSG00000149115 Tankyrase 1 binding protein 1, 182kDa 11 57299638-57324952 Predicted intracellular proteins Evidence at protein level HPA037929, HPA037930 Supported Renal cancer:2.11e-8 (unfavourable) Expressed in all Expressed in all skin: 79.3 TNKS2 PARP-5b, PARP-5c, PARP5B, PARP5C, pART6, TANK2, TNKL ENSG00000107854 Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 10 91798312-91865276 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036606 Approved Microtubules Expressed in all Expressed in all thyroid gland: 50.1 TNPO1 IPO2, KPNB2, MIP, MIP1, TRN ENSG00000083312 Transportin 1 5 72816312-72916733 Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB016325 Approved Supported Nucleoplasm
Cytosol
Cytoplasmic bodies Liver cancer:6.55e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 108.4 TNPO2 FLJ12155, IPO3, KPNB2B, TRN2 ENSG00000105576 Transportin 2 19 12699194-12724011 Predicted intracellular proteins, Transporters Evidence at protein level CAB046446, HPA071498 Approved Approved Nucleus
Nucleoli Endometrial cancer:7.16e-5 (unfavourable), Renal cancer:8.18e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 91.2 TNPO3 IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2 ENSG00000064419 Transportin 3 7 128954180-129055173 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039555, HPA041537 Approved Validated Vesicles Liver cancer:3.29e-5 (unfavourable) Expressed in all Expressed in all testis: 48.3 TNRC18 CAGL79, KIAA1856, TNRC18A ENSG00000182095 Trinucleotide repeat containing 18 7 5306790-5425414 Predicted intracellular proteins Evidence at protein level HPA020730, HPA024251 Uncertain Supported Nucleoplasm
Nuclear membrane
Mitochondria
Cytosol Expressed in all Expressed in all parathyroid gland: 86.2 TNRC6A CAGH26, GW182, KIAA1460, TNRC6 ENSG00000090905 Trinucleotide repeat containing 6A 16 24729695-24827632 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA015305, HPA017869 Approved Approved Nucleoplasm
Golgi apparatus
Vesicles Expressed in all Expressed in all parathyroid gland: 66.9 TNS1 DKFZp586K0617, MXRA6, PPP1R155, TNS ENSG00000079308 Tensin 1 2 217799789-218002995 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB018774, HPA036089, HPA036090 Approved Validated Focal adhesion sites Colorectal cancer:2.41e-4 (unfavourable), Urothelial cancer:5.19e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 316.2 TNS3 FLJ13732, H_NH0549I23.2, TEM6, TENS1 ENSG00000136205 Tensin 3 7 47275154-47582558 Predicted intracellular proteins Evidence at protein level HPA055338, HPA056015 Approved Validated Focal adhesion sites Renal cancer:5.21e-4 (favourable) Expressed in all Expressed in all placenta: 80.9 TOB1 TOB, TROB, TROB1 ENSG00000141232 Transducer of ERBB2, 1 17 50862223-50867978 Predicted intracellular proteins Evidence at protein level HPA047839 Approved Approved Nucleoplasm
Vesicles Pancreatic cancer:5.04e-5 (unfavourable), Prostate cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 280.3 TOB2 bK223H9, TOB4, TOBL, TROB2 ENSG00000183864 Transducer of ERBB2, 2 22 41433492-41447023 Predicted intracellular proteins Evidence at protein level HPA016603, HPA054112 Approved Approved Cytosol Renal cancer:1.18e-6 (favourable), Endometrial cancer:3.08e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 59.1 TOLLIP IL-1RAcPIP ENSG00000078902 Toll interacting protein 11 1274371-1309654 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038621, HPA038622 Supported Approved Plasma membrane
Cytosol Renal cancer:1.11e-16 (favourable), Glioma:4.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 132.7 TOM1 ENSG00000100284 Target of myb1 membrane trafficking protein 22 35299275-35347994 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA000818, HPA001749 Approved Approved Plasma membrane
Microtubule organizing center
Cytosol Endometrial cancer:2.20e-5 (favourable), Renal cancer:3.72e-5 (favourable) Expressed in all Expressed in all esophagus: 54.8 TOM1L2 ENSG00000175662 Target of myb1 like 2 membrane trafficking protein 17 17843511-17972422 Predicted intracellular proteins Evidence at protein level HPA022541, HPA023304 Supported Supported Golgi apparatus
Intermediate filaments Renal cancer:6.21e-9 (favourable), Head and neck cancer:1.24e-4 (favourable), Pancreatic cancer:1.92e-4 (favourable), Ovarian cancer:2.58e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 110.9 TOMM20 KIAA0016, MAS20, MOM19, TOM20 ENSG00000173726 Translocase of outer mitochondrial membrane 20 homolog (yeast) 1 235109336-235128936 Predicted membrane proteins Evidence at protein level CAB005585, HPA011562 Supported Validated Mitochondria Expressed in all Expressed in all cerebral cortex,thyroid gland: 230.5 TOMM22 TOM22 ENSG00000100216 Translocase of outer mitochondrial membrane 22 homolog (yeast) 22 38681948-38685421 Predicted membrane proteins Evidence at protein level HPA003037 Supported Validated Mitochondria Liver cancer:2.90e-5 (unfavourable) Expressed in all Expressed in all fallopian tube: 32.4 TOMM34 HTOM34P, TOM34 ENSG00000025772 Translocase of outer mitochondrial membrane 34 20 44942130-44960486 Predicted intracellular proteins Evidence at protein level HPA018845, HPA056875 Supported Validated Cytosol Liver cancer:8.71e-6 (unfavourable), Head and neck cancer:4.47e-5 (unfavourable), Thyroid cancer:5.45e-4 (favourable) Expressed in all Expressed in all testis: 181.6 TOMM40 C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40 ENSG00000130204 Translocase of outer mitochondrial membrane 40 homolog (yeast) 19 44890569-44903689 Predicted intracellular proteins, Transporters Evidence at protein level HPA036231, HPA036232 Supported Validated Mitochondria
Cytosol Expressed in all Expressed in all appendix: 35.2 TOMM5 bA613M10.3, C9orf105 ENSG00000175768 Translocase of outer mitochondrial membrane 5 homolog (yeast) 9 37582646-37592642 Predicted intracellular proteins Evidence at protein level HPA048712 Approved Supported Mitochondria Liver cancer:2.09e-4 (unfavourable), Ovarian cancer:2.37e-4 (favourable), Melanoma:5.49e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 98.1 TOMM6 OBTP ENSG00000214736 Translocase of outer mitochondrial membrane 6 homolog (yeast) 6 41787662-41789898 Predicted intracellular proteins Evidence at protein level HPA004801 Approved Supported Mitochondria Not detected Expressed in all epididymis: 316.2 TOMM7 ENSG00000196683 Translocase of outer mitochondrial membrane 7 homolog (yeast) 7 22812628-22822852 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level Head and neck cancer:6.30e-4 (unfavourable) Expressed in all Expressed in all ovary: 673.7 TOMM70A KIAA0719 ENSG00000154174 Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 3 100363431-100401398 Predicted membrane proteins Evidence at protein level HPA014589, CAB017156, HPA048020 Supported Validated Mitochondria Expressed in all Expressed in all cerebral cortex: 52.9 TOP1 ENSG00000198900 Topoisomerase (DNA) I 20 41028818-41124487 Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB009058, HPA019039 Supported Supported Nucleus
Nucleoli fibrillar center Liver cancer:6.42e-4 (unfavourable) Expressed in all Expressed in all lymph node: 71.8 TOP1MT ENSG00000184428 Topoisomerase (DNA) I, mitochondrial 8 143304384-143359979 Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001915, HPA021542 Approved Supported Mitochondria Renal cancer:1.52e-7 (unfavourable) Expressed in all Expressed in all testis: 41.2 TOP2B ENSG00000077097 Topoisomerase (DNA) II beta 3 25597905-25664907 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004601, HPA024120, HPA050441 Supported Validated Nucleus Liver cancer:1.86e-7 (unfavourable), Renal cancer:2.43e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 105.5 TOP3A TOP3, ZGRF7 ENSG00000177302 Topoisomerase (DNA) III alpha 17 18271428-18315007 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002449 Approved Pancreatic cancer:1.39e-4 (favourable), Prostate cancer:4.59e-4 (unfavourable) Expressed in all Expressed in all testis: 24.9 TOPBP1 KIAA0259, TOP2BP1 ENSG00000163781 Topoisomerase (DNA) II binding protein 1 3 133598175-133661893 Predicted intracellular proteins Evidence at protein level CAB022451, HPA036738, HPA036739 Approved Validated Nucleus Liver cancer:4.66e-5 (unfavourable), Endometrial cancer:5.76e-5 (unfavourable), Pancreatic cancer:1.88e-4 (unfavourable) Expressed in all Expressed in all testis: 54.0 TOPORS LUN, RP31, TP53BPL ENSG00000197579 Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 9 32540544-32552553 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA060640, HPA065661 Supported Supported Nucleoplasm Renal cancer:6.64e-6 (favourable), Ovarian cancer:7.07e-4 (favourable) Expressed in all Expressed in all parathyroid gland,testis: 27.3 TOR1A DQ2, DYT1 ENSG00000136827 Torsin family 1, member A (torsin A) 9 129812944-129824134 Disease related genes, Predicted secreted proteins Evidence at protein level CAB012473, HPA051195 Approved Supported Nuclear membrane
Vesicles Lung cancer:5.45e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 39.8 TOR1AIP1 FLJ13142, LAP1B ENSG00000143337 Torsin A interacting protein 1 1 179882042-179925000 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA047151, HPA050546 Supported Validated Nuclear membrane Expressed in all Expressed in all thyroid gland: 78.9 TOR1AIP2 IFRG15, LULL1, NET9 ENSG00000169905 Torsin A interacting protein 2 1 179839967-179877803 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA051849, HPA058348, HPA070542 Uncertain Validated Endoplasmic reticulum Renal cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all placenta: 33.9 TOR1B DQ1, MGC4386 ENSG00000136816 Torsin family 1, member B (torsin B) 9 129803153-129811281 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA013403, HPA013697, CAB022709 Approved Approved Nuclear speckles
Cytosol Expressed in all Expressed in all rectum: 25.2 TOR3A ADIR, ADIR2, FLJ22345 ENSG00000186283 Torsin family 3, member A 1 179081377-179098023 Predicted secreted proteins Evidence at protein level HPA028766 Approved Renal cancer:4.78e-8 (unfavourable) Expressed in all Expressed in all lymph node: 42.8 TOX4 C14orf92, KIAA0737, LCP1 ENSG00000092203 TOX high mobility group box family member 4 14 21476597-21499175 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017880, HPA027551 Approved Approved Nucleus
Nucleoli
Vesicles Renal cancer:8.38e-5 (favourable), Liver cancer:3.46e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 34.8 TP53 LFS1, p53 ENSG00000141510 Tumor protein p53 17 7661779-7687550 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters Evidence at protein level CAB002973, CAB039238, CAB039239, HPA051244, CAB072876 Supported Validated Nucleoplasm Endometrial cancer:1.35e-4 (favourable), Prostate cancer:5.01e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 50.3 TP53BP1 53BP1, p202, TDRD30 ENSG00000067369 Tumor protein p53 binding protein 1 15 43403061-43510728 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004083, HPA008788, HPA022133 Supported Validated Nucleoplasm
Nuclear bodies Expressed in all Expressed in all parathyroid gland: 49.6 TP53BP2 53BP2, ASPP2, PPP1R13A ENSG00000143514 Tumor protein p53 binding protein 2 1 223779899-223845972 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA021603, HPA050429 Supported Validated Cell Junctions
Cytosol Expressed in all Expressed in all thyroid gland: 34.4 TP53I11 PIG11 ENSG00000175274 Tumor protein p53 inducible protein 11 11 44885903-44951306 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059727, HPA061276 Uncertain Supported Endoplasmic reticulum
Golgi apparatus Breast cancer:7.33e-5 (unfavourable), Renal cancer:4.65e-4 (unfavourable), Melanoma:6.12e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 58.0 TP53I13 DSCP1 ENSG00000167543 Tumor protein p53 inducible protein 13 17 29566052-29573157 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level Renal cancer:2.10e-6 (unfavourable), Pancreatic cancer:3.13e-5 (favourable) Expressed in all Expressed in all spleen: 54.3 TP53I3 PIG3 ENSG00000115129 Tumor protein p53 inducible protein 3 2 24077433-24085861 Predicted intracellular proteins Evidence at protein level CAB017479, HPA022012, HPA028742 Supported Supported Vesicles Expressed in all Expressed in all esophagus: 97.5 TP53INP1 DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B ENSG00000164938 Tumor protein p53 inducible nuclear protein 1 8 94925972-94949411 Predicted intracellular proteins Evidence at protein level HPA005856 Uncertain Supported Cytosol Urothelial cancer:5.45e-5 (favourable), Head and neck cancer:1.11e-4 (favourable) Expressed in all Expressed in all testis: 52.5 TP53INP2 C20orf110, dJ1181N3.1, DKFZp434B2411, DKFZp434O0827, DOR, FLJ21759, FLJ23500, PINH ENSG00000078804 Tumor protein p53 inducible nuclear protein 2 20 34704290-34713439 Predicted intracellular proteins Evidence at protein level Renal cancer:1.26e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 87.1 TP53RK BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk ENSG00000172315 TP53 regulating kinase 20 46684365-46689779 Enzymes, Predicted intracellular proteins Evidence at protein level CAB004688, HPA015837 Approved Liver cancer:6.27e-5 (unfavourable), Endometrial cancer:6.70e-5 (unfavourable) Expressed in all Expressed in all testis: 16.5 TPCN1 FLJ20612, KIAA1169, TPC1 ENSG00000186815 Two pore segment channel 1 12 113221050-113298585 Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels Evidence at protein level HPA039757 Approved Expressed in all Expressed in all thyroid gland: 53.3 TPD52 D52, hD52, N8L ENSG00000076554 Tumor protein D52 8 80034745-80231232 Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA028427, HPA062167 Supported Approved Golgi apparatus
Cytosol Renal cancer:4.77e-6 (unfavourable), Breast cancer:1.11e-5 (unfavourable) Expressed in all Expressed in all prostate: 173.6 TPD52L2 D54, hD54 ENSG00000101150 Tumor protein D52-like 2 20 63865228-63891545 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047489 Approved Approved Vesicles
Cytosol Renal cancer:1.74e-8 (unfavourable), Liver cancer:1.39e-5 (unfavourable) Expressed in all Expressed in all smooth muscle: 103.8 TPGS2 C18orf10, DKFZP586M1523, HsT3006 ENSG00000134779 Tubulin polyglutamylase complex subunit 2 18 36777647-36829216 Predicted intracellular proteins Evidence at protein level HPA040596, HPA040617, HPA061753 Uncertain Supported Nucleoli Liver cancer:1.24e-5 (unfavourable), Ovarian cancer:1.93e-5 (favourable), Cervical cancer:4.09e-4 (favourable), Testis cancer:7.74e-4 (favourable) Expressed in all Expressed in all testis: 364.7 TPI1 ENSG00000111669 Triosephosphate isomerase 1 12 6867119-6870948 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA050924, HPA053568 Uncertain Validated Nucleoplasm Liver cancer:1.04e-5 (unfavourable), Renal cancer:6.54e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 942.9 TPM1 C15orf13, CMH3 ENSG00000140416 Tropomyosin 1 (alpha) 15 63042632-63071915 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000261, HPA009066, CAB017698, HPA047089, HPA053624 Supported Approved Actin filaments
Cytosol Urothelial cancer:7.30e-4 (unfavourable) Expressed in all Expressed in all heart muscle: 6465.2 TPM4 ENSG00000167460 Tropomyosin 4 19 16067021-16103005 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004685, HPA047089, HPA053624 Approved Approved Actin filaments
Cytosol Renal cancer:1.26e-10 (unfavourable), Pancreatic cancer:3.07e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 808.6 TPMT ENSG00000137364 Thiopurine S-methyltransferase 6 18128311-18155074 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA019851 Approved Endometrial cancer:8.45e-5 (unfavourable), Renal cancer:1.10e-4 (favourable), Ovarian cancer:1.41e-4 (favourable) Expressed in all Expressed in all thyroid gland: 129.4 TPP1 CLN2, SCAR7 ENSG00000166340 Tripeptidyl peptidase I 11 6612763-6619461 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA037709, HPA044868 Supported Liver cancer:1.11e-4 (unfavourable), Head and neck cancer:4.31e-4 (unfavourable), Stomach cancer:4.46e-4 (unfavourable) Expressed in all Expressed in all spleen: 210.1 TPP2 TPPII ENSG00000134900 Tripeptidyl peptidase II 13 102597003-102679958 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021069, HPA049630 Approved Supported Nuclear bodies
Cytosol Expressed in all Expressed in all testis: 66.5 TPR ENSG00000047410 Translocated promoter region, nuclear basket protein 1 186311652-186375693 Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level HPA019661, HPA019663, HPA024336 Supported Validated Nuclear membrane Liver cancer:1.06e-4 (unfavourable), Head and neck cancer:4.71e-4 (favourable) Expressed in all Expressed in all testis: 78.8 TPRA1 FLJ32197, GPR175, TMEM227, TPRA40 ENSG00000163870 Transmembrane protein, adipocyte asscociated 1 3 127573069-127598251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019784 Approved Approved Vesicles Liver cancer:6.46e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 38.1 TPRG1L FAM79A, FLJ21811, RP11-46F15.3 ENSG00000158109 Tumor protein p63 regulated 1-like 1 3625002-3630127 Predicted intracellular proteins Evidence at protein level HPA063163 Approved Vesicles
Cytosol Renal cancer:1.76e-9 (favourable) Expressed in all Expressed in all cerebral cortex: 102.5 TPRKB CGI-121 ENSG00000144034 TP53RK binding protein 2 73729104-73737400 Predicted intracellular proteins Evidence at protein level HPA035712 Approved Supported Cytosol Expressed in all Expressed in all testis: 79.3 TPRN C9orf75, DFNB79, FLJ90254 ENSG00000176058 Taperin 9 137191617-137204193 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020899 Uncertain Approved Plasma membrane Renal cancer:5.16e-9 (favourable), Cervical cancer:2.13e-4 (favourable) Expressed in all Expressed in all small intestine: 28.9 TPST2 TANGO13B ENSG00000128294 Tyrosylprotein sulfotransferase 2 22 26521983-26596717 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021054 Approved Renal cancer:2.34e-6 (unfavourable), Endometrial cancer:8.08e-5 (favourable) Expressed in all Expressed in all epididymis: 133.6 TPT1 fortilin, TCTP ENSG00000133112 Tumor protein, translationally-controlled 1 13 45333471-45341370 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008364, HPA039437 Approved Supported Cytosol Renal cancer:2.54e-5 (unfavourable), Thyroid cancer:4.31e-5 (favourable), Breast cancer:5.90e-5 (favourable), Endometrial cancer:2.35e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 8105.5 TRA2A AWMS1, htra-2-alpha, tra2a ENSG00000164548 Transformer 2 alpha homolog (Drosophila) 7 23504780-23532041 Predicted intracellular proteins Evidence at protein level HPA054018 Uncertain Supported Nucleoli
Vesicles Renal cancer:1.79e-6 (unfavourable), Liver cancer:2.07e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 65.5 TRA2B Htra2-beta, PPP1R156, SFRS10 ENSG00000136527 Transformer 2 beta homolog (Drosophila) 3 185915906-185938136 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011692, HPA063597, HPA064972 Supported Validated Nucleoplasm Ovarian cancer:2.15e-4 (favourable), Liver cancer:8.51e-4 (unfavourable) Expressed in all Expressed in all appendix: 58.5 TRABD PP2447 ENSG00000170638 TraB domain containing 22 50185915-50199598 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA000822 Approved Approved Nucleus
Mitochondria Endometrial cancer:1.19e-5 (favourable), Renal cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 38.6 TRAF2 TRAP3 ENSG00000127191 TNF receptor-associated factor 2 9 136881912-136926607 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004603, HPA009972, HPA010634 Uncertain Validated Cytosol Renal cancer:2.09e-4 (unfavourable), Liver cancer:3.06e-4 (unfavourable), Colorectal cancer:9.32e-4 (unfavourable) Expressed in all Expressed in all lymph node: 23.1 TRAF3IP1 DKFZP434F124, IFT54, MIP-T3, MIPT3 ENSG00000204104 TNF receptor-associated factor 3 interacting protein 1 2 238320441-238400900 Predicted intracellular proteins Evidence at protein level HPA037857, HPA037858 Approved Melanoma:2.19e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 30.9 TRAF3IP2 ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZP586G0522 ENSG00000056972 TRAF3 interacting protein 2 6 111556454-111606278 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA036352 Approved Approved Golgi apparatus
Vesicles Endometrial cancer:4.73e-5 (favourable), Renal cancer:5.16e-5 (unfavourable), Cervical cancer:3.21e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 49.4 TRAF6 RNF85 ENSG00000175104 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 11 36487027-36510272 Predicted intracellular proteins Evidence at protein level CAB004605, HPA019805, HPA020599 Approved Supported Nucleoli
Mitochondria Renal cancer:1.36e-4 (favourable) Expressed in all Expressed in all thyroid gland: 16.2 TRAF7 DKFZp586I021, MGC7807, RFWD1, RNF119 ENSG00000131653 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 16 2155698-2178129 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA041229 Approved Supported Vesicles
Plasma membrane Expressed in all Expressed in all duodenum: 41.1 TRAFD1 FLN29 ENSG00000135148 TRAF-type zinc finger domain containing 1 12 112125501-112153609 Predicted intracellular proteins Evidence at protein level HPA039254, HPA039266 Supported Approved Nucleoplasm
Cytosol Renal cancer:9.26e-6 (unfavourable), Urothelial cancer:3.92e-5 (favourable), Liver cancer:4.87e-4 (unfavourable), Cervical cancer:5.73e-4 (favourable) Expressed in all Expressed in all testis: 53.6 TRAK1 KIAA1042, MILT1, OIP106 ENSG00000182606 Trafficking protein, kinesin binding 1 3 42013802-42225889 Predicted intracellular proteins Evidence at protein level HPA005853, HPA011367 Approved Approved Nucleoplasm
Endoplasmic reticulum Renal cancer:4.84e-8 (favourable) Expressed in all Expressed in all heart muscle: 111.9 TRAK2 ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98 ENSG00000115993 Trafficking protein, kinesin binding 2 2 201377207-201451611 Predicted intracellular proteins Evidence at protein level HPA015827, HPA062163 Uncertain Approved Nucleoplasm
Nuclear bodies
Vesicles Renal cancer:7.42e-5 (favourable) Expressed in all Expressed in all thyroid gland: 55.7 TRAM1 TRAM, TRAMP ENSG00000067167 Translocation associated membrane protein 1 8 70573442-70608387 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA023929 Approved Cervical cancer:2.06e-4 (unfavourable), Renal cancer:7.79e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 316.6 TRAM2 KIAA0057 ENSG00000065308 Translocation associated membrane protein 2 6 52497402-52576915 Predicted membrane proteins Evidence at protein level HPA035092, HPA057925 Approved Approved Cytosol Renal cancer:1.41e-9 (unfavourable), Endometrial cancer:1.88e-4 (unfavourable) Expressed in all Expressed in all placenta: 51.8 TRAP1 HSP75, HSP90L ENSG00000126602 TNF receptor-associated protein 1 16 3651639-3717597 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041082, HPA044227 Supported Validated Mitochondria Colorectal cancer:1.80e-4 (favourable) Expressed in all Expressed in all fallopian tube: 94.4 TRAPPC1 BET5, MUM2 ENSG00000170043 Trafficking protein particle complex 1 17 7930345-7932123 Predicted intracellular proteins Evidence at protein level HPA052398 Approved Expressed in all Expressed in all placenta: 163.9 TRAPPC10 EHOC-1, TMEM1, TRS130 ENSG00000160218 Trafficking protein particle complex 10 21 44012319-44106552 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050423 Supported Expressed in all Expressed in all parathyroid gland: 14.1 TRAPPC11 C4orf41, FLJ12716, foigr, gry ENSG00000168538 Trafficking protein particle complex 11 4 183659267-183713594 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA045427 Approved Nucleoplasm
Nuclear membrane Renal cancer:2.66e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 36.6 TRAPPC12 CGI-87, TTC-15, TTC15 ENSG00000171853 Trafficking protein particle complex 12 2 3379675-3485094 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA034799 Uncertain Breast cancer:1.80e-5 (favourable), Renal cancer:2.44e-4 (unfavourable), Pancreatic cancer:9.15e-4 (favourable) Expressed in all Expressed in all testis: 48.8 TRAPPC13 C5orf44, FLJ13611, FLJ26957, MGC48585 ENSG00000113597 Trafficking protein particle complex 13 5 65624716-65666233 Predicted intracellular proteins Evidence at protein level HPA037777 Approved Approved Nucleus
Plasma membrane Renal cancer:8.66e-4 (favourable) Expressed in all Expressed in all prostate: 30.0 TRAPPC2 hYP38334, MIP-2A, SEDL, SEDT, TRAPPC2, TRS20, ZNF547L ENSG00000196459 Trafficking protein particle complex 2 X 13712244-13734635 Disease related genes, Predicted intracellular proteins Evidence at protein level CAB004665, HPA063308 Approved Approved Nucleoplasm
Endoplasmic reticulum
Vesicles Urothelial cancer:7.89e-5 (favourable), Ovarian cancer:6.35e-4 (favourable), Cervical cancer:8.09e-4 (favourable) Expressed in all Expressed in all cerebral cortex,lymph node: 16.6 TRAPPC2L HSPC176 ENSG00000167515 Trafficking protein particle complex 2-like 16 88856220-88862686 Predicted intracellular proteins Evidence at protein level HPA041714 Approved Supported Vesicles
Cytosol Endometrial cancer:3.75e-4 (favourable) Expressed in all Expressed in all adrenal gland: 91.9 TRAPPC2P1 ENSG00000256060 Trafficking protein particle complex subunit 2B 19 57363511-57365353 Predicted intracellular proteins Evidence at protein level HPA063308 Approved Nucleoplasm
Endoplasmic reticulum
Vesicles Renal cancer:1.28e-4 (favourable) Expressed in all Expressed in all testis: 28.7 TRAPPC3 BET3 ENSG00000054116 Trafficking protein particle complex 3 1 36136570-36156053 Predicted intracellular proteins Evidence at protein level HPA028408 Approved Approved Golgi apparatus
Cytosol Liver cancer:2.70e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 101.6 TRAPPC4 PTD009, SBDN, TRS23 ENSG00000196655 Trafficking protein particle complex 4 11 119018432-119025454 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039752, HPA041371 Approved Approved Cytosol Liver cancer:2.03e-5 (unfavourable) Expressed in all Expressed in all testis: 14.8 TRAPPC5 MGC52424, TRS31 ENSG00000181029 Trafficking protein particle complex 5 19 7680843-7687703 Predicted intracellular proteins Evidence at protein level HPA042221, HPA049064 Uncertain Approved Vesicles Mixed Expressed in all testis: 70.0 TRAPPC6A HSPC289, MGC2650, TRS33 ENSG00000007255 Trafficking protein particle complex 6A 19 45162928-45178237 Predicted intracellular proteins Evidence at protein level HPA043043 Approved Renal cancer:2.23e-6 (favourable) Expressed in all Expressed in all thyroid gland: 47.4 TRAPPC6B ENSG00000182400 Trafficking protein particle complex 6B 14 39147811-39170532 Predicted intracellular proteins Evidence at protein level HPA047928 Uncertain Approved Endoplasmic reticulum Renal cancer:1.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 45.9 TRAPPC8 GSG1, HsT2706, KIAA1012, TRS85 ENSG00000153339 Trafficking protein particle complex 8 18 31829173-31953136 Predicted intracellular proteins Evidence at protein level HPA041107 Approved Approved Microtubules
Cytosol Renal cancer:1.85e-9 (favourable) Expressed in all Expressed in all testis: 53.9 TRAPPC9 IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120 ENSG00000167632 Trafficking protein particle complex 9 8 139730343-140458579 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026579 Approved Nucleoplasm
Golgi apparatus
Vesicles Renal cancer:5.11e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 48.7 TREX1 AGS1, DRN3 ENSG00000213689 Three prime repair exonuclease 1 3 48465811-48467645 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA035437 Supported Not detected Expressed in all spleen: 28.4 TRIAP1 HSPC132, MDM35, P53CSV, WF-1 ENSG00000170855 TP53 regulated inhibitor of apoptosis 1 12 120443961-120446412 Predicted intracellular proteins, Transporters Evidence at protein level HPA053640 Approved Approved Nucleoplasm
Mitochondria Melanoma:2.22e-4 (unfavourable), Renal cancer:8.77e-4 (unfavourable) Expressed in all Expressed in all placenta: 40.0 TRIB1 C8FW, GIG2, TRB1 ENSG00000173334 Tribbles pseudokinase 1 8 125430321-125438405 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063982 Approved Plasma membrane Expressed in all Expressed in all bone marrow: 244.0 TRIB2 GS3955, TRB2 ENSG00000071575 Tribbles pseudokinase 2 2 12716889-12742734 Enzymes, Predicted membrane proteins Evidence at protein level HPA001305 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 116.8 TRIM13 DLEU5, Leu5, RFP2, RNF77 ENSG00000204977 Tripartite motif containing 13 13 49995888-50020481 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000367 Approved Expressed in all Expressed in all testis: 140.9 TRIM16 EBBP ENSG00000221926 Tripartite motif containing 16 17 15627960-15684311 Predicted intracellular proteins Evidence at protein level HPA023623, HPA066431 Uncertain Supported Plasma membrane
Cytosol Liver cancer:3.94e-4 (unfavourable), Urothelial cancer:6.71e-4 (unfavourable) Expressed in all Expressed in all esophagus: 118.3 TRIM21 RNF81, Ro/SSA, RO52, SSA1 ENSG00000132109 Tripartite motif containing 21 11 4384897-4393696 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004566, HPA005673 Approved Approved Nucleoplasm Thyroid cancer:2.26e-6 (favourable), Breast cancer:4.83e-5 (favourable), Liver cancer:1.87e-4 (unfavourable) Expressed in all Expressed in all spleen: 41.8 TRIM22 GPSTAF50, RNF94, STAF50 ENSG00000132274 Tripartite motif containing 22 11 5689689-5737089 Predicted intracellular proteins Evidence at protein level HPA003307, HPA003575 Approved Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all spleen: 181.2 TRIM23 ARD1, ARFD1, RNF46 ENSG00000113595 Tripartite motif containing 23 5 65589680-65625975 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA039605 Approved Expressed in all Expressed in all cerebral cortex: 47.0 TRIM24 hTIF1, RNF82, TIF1, Tif1a ENSG00000122779 Tripartite motif containing 24 7 138460334-138589993 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA043495, HPA061717 Approved Validated Nucleoplasm Lung cancer:6.57e-4 (favourable), Liver cancer:9.94e-4 (unfavourable) Expressed in all Expressed in all testis: 49.5 TRIM25 EFP, RNF147, ZNF147 ENSG00000121060 Tripartite motif containing 25 17 56887909-56914038 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005909 Approved Approved Nucleoplasm
Nuclear bodies
Cytosol Pancreatic cancer:3.36e-4 (favourable), Stomach cancer:9.35e-4 (favourable), Liver cancer:9.37e-4 (unfavourable) Expressed in all Expressed in all skin: 34.9 TRIM28 KAP1, PPP1R157, RNF96, TF1B, TIF1B ENSG00000130726 Tripartite motif containing 28 19 58544091-58550722 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB010066, HPA064033 Supported Validated Nucleoplasm Liver cancer:1.85e-6 (unfavourable) Expressed in all Expressed in all ovary: 215.6 TRIM33 FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA ENSG00000197323 Tripartite motif containing 33 1 114392777-114511160 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA004345 Supported Approved Nucleoplasm
Vesicles Colorectal cancer:6.20e-4 (favourable), Head and neck cancer:8.93e-4 (favourable) Expressed in all Expressed in all testis: 46.0 TRIM35 HLS5, KIAA1098, MAIR ENSG00000104228 Tripartite motif containing 35 8 27284887-27311319 Predicted intracellular proteins Evidence at protein level HPA019647 Uncertain Approved Nucleoplasm Renal cancer:5.59e-7 (favourable), Head and neck cancer:1.38e-4 (favourable) Expressed in all Expressed in all skin: 14.6 TRIM37 KIAA0898, MUL, POB1, TEF3 ENSG00000108395 Tripartite motif containing 37 17 58982638-59106921 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021911 Uncertain Liver cancer:4.99e-6 (unfavourable) Expressed in all Expressed in all testis: 117.1 TRIM4 RNF87 ENSG00000146833 Tripartite motif containing 4 7 99876958-99919600 Predicted intracellular proteins Evidence at protein level HPA019356, HPA029461 Approved Supported Plasma membrane
Cytosol Renal cancer:7.36e-6 (favourable) Expressed in all Expressed in all ovary: 50.7 TRIM41 MGC1127, RINCK ENSG00000146063 Tripartite motif containing 41 5 181222499-181235809 Predicted intracellular proteins Evidence at protein level HPA024204 Approved Supported Nucleoli
Nuclear bodies Thyroid cancer:4.22e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.5 TRIM44 DIPB, MC7 ENSG00000166326 Tripartite motif containing 44 11 35662805-35818007 Predicted intracellular proteins Evidence at protein level HPA049053, HPA057633 Approved Approved Vesicles
Plasma membrane Liver cancer:5.24e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.8 TRIM52 RNF102 ENSG00000183718 Tripartite motif containing 52 5 181254417-181261139 Predicted intracellular proteins Evidence at protein level HPA054565, HPA056819 Uncertain Supported Nucleoli
Intermediate filaments Renal cancer:3.46e-4 (unfavourable), Urothelial cancer:4.07e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 17.9 TRIM56 RNF109 ENSG00000169871 Tripartite motif containing 56 7 101085439-101097967 Predicted intracellular proteins Evidence at protein level HPA024358 Approved Approved Nucleoplasm
Cytosol Urothelial cancer:2.13e-4 (favourable), Liver cancer:3.87e-4 (unfavourable) Expressed in all Expressed in all spleen: 30.1 TRIM65 ENSG00000141569 Tripartite motif containing 65 17 75880335-75897003 Predicted intracellular proteins Evidence at protein level HPA021575, HPA021578, HPA064820 Approved Supported Nucleoplasm
Vesicles
Cytosol Liver cancer:4.74e-6 (unfavourable), Renal cancer:1.82e-5 (unfavourable) Expressed in all Expressed in all skin: 20.4 TRIM68 FLJ10369, RNF137, SS-56 ENSG00000167333 Tripartite motif containing 68 11 4598672-4608259 Predicted intracellular proteins Evidence at protein level HPA023455 Uncertain Supported Nucleus
Cytosol Renal cancer:4.14e-6 (favourable) Expressed in all Expressed in all thyroid gland: 16.0 TRIM8 GERP, RNF27 ENSG00000171206 Tripartite motif containing 8 10 102644496-102658407 Predicted intracellular proteins Evidence at protein level HPA023560, HPA023561 Approved Validated Nucleoplasm
Vesicles
Cytosol Expressed in all Expressed in all adipose tissue: 60.7 TRIO ARHGEF23 ENSG00000038382 Trio Rho guanine nucleotide exchange factor 5 14143702-14532128 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008157, HPA064664 Supported Approved Vesicles
Cytosol Renal cancer:3.11e-5 (unfavourable), Endometrial cancer:1.90e-4 (unfavourable) Expressed in all Expressed in all breast: 30.8 TRIOBP DFNB28, HRIHFB2122, KIAA1662, TAP68, Tara ENSG00000100106 TRIO and F-actin binding protein 22 37697004-37776556 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003747, HPA019769 Supported Uncertain Cytosol Cervical cancer:4.29e-4 (favourable) Expressed in all Expressed in all spleen: 67.1 TRIP10 CIP4, HSTP, STOT, STP ENSG00000125733 Thyroid hormone receptor interactor 10 19 6737925-6751526 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041934 Supported Nucleoplasm
Vesicles Head and neck cancer:1.76e-4 (favourable), Colorectal cancer:3.61e-4 (unfavourable), Renal cancer:4.66e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 129.1 TRIP11 CEV14, GMAP-210, GMAP210, Trip230 ENSG00000100815 Thyroid hormone receptor interactor 11 14 91965991-92040896 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002570, HPA070684 Supported Validated Nucleus
Golgi apparatus Renal cancer:1.78e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 37.7 TRIP12 KIAA0045 ENSG00000153827 Thyroid hormone receptor interactor 12 2 229763838-229923239 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036835, HPA045893 Supported Approved Nuclear speckles Liver cancer:3.60e-4 (unfavourable) Expressed in all Expressed in all testis: 271.5 TRIP4 HsT17391, ZC2HC5 ENSG00000103671 Thyroid hormone receptor interactor 4 15 64387748-64455303 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA016605, HPA050666 Approved Supported Nucleoplasm
Nuclear bodies Renal cancer:6.34e-6 (favourable) Expressed in all Expressed in all thyroid gland: 42.0 TRIP6 MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1 ENSG00000087077 Thyroid hormone receptor interactor 6 7 100867138-100873454 Predicted intracellular proteins Evidence at protein level CAB046454, CAB046460, HPA052813 Approved Supported Plasma membrane
Focal adhesion sites
Cytosol Expressed in all Expressed in all parathyroid gland: 84.3 TRIT1 FLJ20061, IPT ENSG00000043514 TRNA isopentenyltransferase 1 1 39841022-39883511 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024174 Approved Approved Nucleoplasm
Cytosol Renal cancer:7.08e-8 (unfavourable), Liver cancer:5.34e-6 (unfavourable), Endometrial cancer:8.80e-4 (unfavourable) Expressed in all Expressed in all endometrium: 24.9 TRMO C9orf156, HSPC219 ENSG00000136932 TRNA methyltransferase O 9 97904489-97922570 Predicted intracellular proteins Evidence at protein level HPA021281, HPA052197 Approved Approved Nucleoplasm Renal cancer:4.81e-10 (favourable) Expressed in all Expressed in all thyroid gland: 29.5 TRMT1 FLJ20244, TRM1 ENSG00000104907 TRNA methyltransferase 1 19 13104902-13117567 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041130, HPA041380 Approved Approved Nucleus
Plasma membrane
Cytosol Renal cancer:9.87e-7 (unfavourable) Expressed in all Expressed in all lymph node: 27.0 TRMT10A MGC27034, RG9MTD2, TRM10 ENSG00000145331 TRNA methyltransferase 10A 4 99546709-99564032 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047601, HPA058241 Uncertain Approved Nucleoplasm
Nucleoli
Actin filaments
Cytosol Thyroid cancer:2.14e-4 (unfavourable) Expressed in all Expressed in all testis: 21.1 TRMT10C FLJ20432, MRPP1, RG9MTD1 ENSG00000174173 TRNA methyltransferase 10C, mitochondrial RNase P subunit 3 101561862-101566446 Predicted intracellular proteins Evidence at protein level HPA036671 Approved Supported Nucleoplasm
Mitochondria Renal cancer:3.32e-5 (favourable), Liver cancer:6.56e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.7 TRMT11 C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1 ENSG00000066651 TRNA methyltransferase 11 homolog 6 125986430-126039276 Predicted intracellular proteins Evidence at protein level HPA030473 Approved Nuclear bodies Expressed in all Expressed in all endometrium: 23.3 TRMT112 HSPC152, HSPC170, hTrm112, TRM112, TRMT11-2 ENSG00000173113 TRNA methyltransferase 11-2 homolog (S. cerevisiae) 11 64316460-64318084 Predicted intracellular proteins Evidence at protein level HPA039901, HPA040006 Uncertain Approved Nucleus
Microtubules Head and neck cancer:1.62e-4 (unfavourable), Renal cancer:2.78e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 305.2 TRMT13 CCDC76, FLJ10287, FLJ11219 ENSG00000122435 TRNA methyltransferase 13 homolog (S. cerevisiae) 1 100133150-100150497 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028494 Approved Approved Nucleoplasm
Nuclear bodies
Plasma membrane
Cytosol Renal cancer:6.89e-6 (unfavourable), Liver cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.8 TRMT2A HTF9C ENSG00000099899 TRNA methyltransferase 2 homolog A 22 20111866-20117392 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001077 Approved Approved Nucleus
Cytosol Renal cancer:2.99e-8 (unfavourable) Expressed in all Expressed in all spleen: 16.9 TRMT2B CXorf34, FLJ12687 ENSG00000188917 TRNA methyltransferase 2 homolog B X 101009346-101052116 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003745, HPA035120, HPA040814 Uncertain Approved Nucleoplasm
Nuclear bodies Renal cancer:2.30e-7 (favourable), Breast cancer:1.58e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.0 TRMT5 KIAA1393, TRM5 ENSG00000126814 TRNA methyltransferase 5 14 60971451-60981358 Enzymes, Predicted intracellular proteins Evidence at protein level HPA000943 Supported Approved Nucleus
Nucleoli Expressed in all Expressed in all testis: 31.1 TRMT6 CGI-09, GCD10, Gcd10p, MGC5029 ENSG00000089195 TRNA methyltransferase 6 20 5937235-5950558 Predicted intracellular proteins Evidence at protein level HPA047032, HPA050408 Approved Supported Nucleus Liver cancer:4.70e-12 (unfavourable) Expressed in all Expressed in all testis: 25.3 TRMT61A C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61 ENSG00000166166 TRNA methyltransferase 61A 14 103529184-103537073 Enzymes, Predicted intracellular proteins Evidence at protein level Liver cancer:1.60e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 10.0 TRMT61B FLJ20628 ENSG00000171103 TRNA methyltransferase 61B 2 28849821-28870301 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026747, HPA026751 Supported Uncertain Cytosol Renal cancer:9.61e-5 (favourable), Liver cancer:3.61e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.0 TRMU FLJ10140, MTO2, TRMT ENSG00000100416 TRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 22 46330875-46357340 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035273, HPA043300 Uncertain Supported Nucleoplasm
Mitochondria Renal cancer:5.63e-6 (unfavourable), Liver cancer:3.04e-5 (unfavourable), Pancreatic cancer:6.86e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 16.6 TRNT1 CCA1, CGI-47, MtCCA ENSG00000072756 TRNA nucleotidyl transferase, CCA-adding, 1 3 3126916-3150879 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA036938 Uncertain Validated Mitochondria Expressed in all Expressed in all prostate: 26.1 TROVE2 Ro60, SSA2 ENSG00000116747 TROVE domain family, member 2 1 193059422-193091777 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002835, HPA005142 Uncertain Approved Nucleoplasm
Cytosol Thyroid cancer:3.31e-4 (unfavourable) Expressed in all Expressed in all prostate: 28.6 TRPC4AP C20orf188, dJ756N5.2, DKFZp586C1223, DKFZP727M231, PPP1R158, TRRP4AP ENSG00000100991 Transient receptor potential cation channel, subfamily C, member 4 associated protein 20 35002404-35092871 Predicted intracellular proteins Evidence at protein level HPA051197, HPA065061 Uncertain Approved Cytosol Liver cancer:6.25e-8 (unfavourable), Renal cancer:1.17e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 71.2 TRPT1 MGC11134 ENSG00000149743 TRNA phosphotransferase 1 11 64223799-64226254 Enzymes, Predicted intracellular proteins Evidence at protein level HPA038705, HPA038706 Uncertain Approved Mitochondria Expressed in all Expressed in all testis: 44.8 TRRAP PAF400, TR-AP, Tra1 ENSG00000196367 Transformation/transcription domain-associated protein 7 98877933-99013243 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA054376 Supported Nucleoplasm
Golgi apparatus Liver cancer:8.77e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.2 TRUB1 PUS4 ENSG00000165832 TruB pseudouridine (psi) synthase family member 1 10 114938193-114977676 Predicted intracellular proteins Evidence at protein level HPA037914, HPA057552 Approved Supported Vesicles
Actin filaments Expressed in all Expressed in all adrenal gland: 38.7 TSC1 hamartin, KIAA0243, LAM, TSC ENSG00000165699 Tuberous sclerosis 1 9 132891348-132944633 Cancer-related genes, Disease related genes, Plasma proteins, Predicted membrane proteins Evidence at protein level CAB011568, CAB012481, HPA074132 Supported Validated Cytosol Liver cancer:6.03e-6 (unfavourable), Renal cancer:7.91e-4 (favourable), Pancreatic cancer:8.01e-4 (favourable) Expressed in all Expressed in all testis: 34.3 TSC2 LAM, PPP1R160, TSC4, tuberin ENSG00000103197 Tuberous sclerosis 2 16 2047465-2088720 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB002225, HPA030409, HPA049679 Approved Validated Cytosol Pancreatic cancer:5.06e-4 (favourable) Expressed in all Expressed in all seminal vesicle: 35.7 TSC22D1 MGC17597, TGFB1I4, TSC22 ENSG00000102804 TSC22 domain family, member 1 13 44432143-44577147 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077414 Approved Nucleoplasm
Nuclear bodies Renal cancer:4.54e-4 (favourable), Ovarian cancer:7.97e-4 (unfavourable) Expressed in all Expressed in all prostate: 263.0 TSC22D2 KIAA0669, TILZ4a, TILZ4b, TILZ4c ENSG00000196428 TSC22 domain family, member 2 3 150408335-150466431 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004926 Approved Approved Cytosol Endometrial cancer:2.74e-4 (unfavourable), Renal cancer:5.80e-4 (unfavourable) Expressed in all Expressed in all endometrium: 37.8 TSC22D3 DIP, DSIPI, GILZ, hDIP, TSC-22R ENSG00000157514 TSC22 domain family, member 3 X 107713221-107777342 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001916 Approved Nuclear speckles
Golgi apparatus
Cytosol Endometrial cancer:2.43e-4 (unfavourable) Expressed in all Expressed in all appendix: 554.1 TSC22D4 THG-1, TILZ2 ENSG00000166925 TSC22 domain family, member 4 7 100463359-100479279 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA006757 Uncertain Approved Cytosol Colorectal cancer:2.66e-4 (unfavourable), Liver cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 278.9 TSEN15 C1orf19 ENSG00000198860 TSEN15 tRNA splicing endonuclease subunit 1 184051677-184074212 Predicted intracellular proteins Evidence at protein level HPA029237 Approved Approved Nucleus
Nucleoli Renal cancer:3.66e-10 (unfavourable), Liver cancer:2.07e-5 (unfavourable), Ovarian cancer:4.59e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.7 TSEN2 MGC2776, SEN2, SEN2L ENSG00000154743 TSEN2 tRNA splicing endonuclease subunit 3 12484432-12539623 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027120, HPA027125, HPA027268 Approved Validated Nucleoplasm
Cytosol Liver cancer:1.13e-5 (unfavourable), Urothelial cancer:3.49e-4 (favourable) Expressed in all Expressed in all endometrium: 14.2 TSEN54 SEN54, SEN54L ENSG00000182173 TSEN54 tRNA splicing endonuclease subunit 17 75516060-75524739 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA053097 Uncertain Liver cancer:8.06e-6 (unfavourable), Pancreatic cancer:2.62e-5 (favourable), Stomach cancer:7.78e-5 (favourable), Urothelial cancer:8.54e-4 (favourable) Expressed in all Expressed in all skin: 20.4 TSFM EF-TS, EF-Tsmt ENSG00000123297 Ts translation elongation factor, mitochondrial 12 57782589-57808071 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA006204 Supported Nucleus
Mitochondria Renal cancer:8.82e-4 (favourable) Expressed in all Expressed in all adrenal gland: 64.0 TSG101 TSG10, VPS23 ENSG00000074319 Tumor susceptibility 101 11 18468336-18527232 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004283, HPA006161 Approved Supported Nucleoli
Plasma membrane
Cytosol Liver cancer:3.74e-6 (unfavourable), Renal cancer:5.52e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 80.4 TSHZ1 NY-CO-33, SDCCAG33, TSH1 ENSG00000179981 Teashirt zinc finger homeobox 1 18 75210755-75289950 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006982 Approved Approved Nucleoplasm Thyroid cancer:1.71e-5 (unfavourable) Expressed in all Expressed in all ovary: 46.3 TSKU E2IG4, LRRC54, TSK ENSG00000182704 Tsukushi, small leucine rich proteoglycan 11 76782251-76798154 Predicted secreted proteins Evidence at protein level HPA008164 Approved Approved Nucleus
Nuclear bodies Renal cancer:2.80e-8 (unfavourable), Prostate cancer:1.66e-4 (favourable), Pancreatic cancer:2.87e-4 (unfavourable), Endometrial cancer:3.66e-4 (favourable) Expressed in all Expressed in all liver: 114.5 TSN BCLF-1, REHF-1, TRSLN ENSG00000211460 Translin 2 121737103-121767853 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA059561 Uncertain Liver cancer:3.06e-4 (unfavourable), Endometrial cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all testis: 40.9 TSNARE1 FLJ31164 ENSG00000171045 T-SNARE domain containing 1 8 142212080-142403240 Predicted intracellular proteins, Predicted membrane proteins Evidence at transcript level HPA015890 Approved Nucleus Urothelial cancer:7.33e-4 (favourable) Expressed in all Expressed in all skin: 29.2 TSNAX TRAX ENSG00000116918 Translin-associated factor X 1 231528653-231566524 Predicted intracellular proteins Evidence at protein level HPA031054, HPA031055, CAB034263 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 53.4 TSPAN13 NET-6, TM4SF13 ENSG00000106537 Tetraspanin 13 7 16753535-16784536 Predicted membrane proteins Evidence at protein level HPA007426 Uncertain Approved Nucleus Glioma:5.27e-5 (unfavourable), Ovarian cancer:2.20e-4 (favourable), Renal cancer:2.43e-4 (unfavourable), Liver cancer:2.94e-4 (unfavourable) Expressed in all Expressed in all lung: 246.3 TSPAN14 DC-TM4F2, MGC11352, TM4SF14 ENSG00000108219 Tetraspanin 14 10 80454166-80533123 Predicted membrane proteins Evidence at protein level HPA014773, HPA057174 Uncertain Supported Vesicles Cervical cancer:3.56e-4 (favourable), Renal cancer:4.20e-4 (favourable) Expressed in all Expressed in all placenta: 128.3 TSPAN17 FBX23, FBXO23, TM4SF17 ENSG00000048140 Tetraspanin 17 5 176647387-176659054 Predicted membrane proteins Evidence at transcript level HPA030447 Approved Nucleoplasm Expressed in all Expressed in all bone marrow: 34.8 TSPAN3 TM4-A, TM4SF8, TSPAN-3 ENSG00000140391 Tetraspanin 3 15 77041404-77083984 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015996 Uncertain Approved Nucleoplasm
Golgi apparatus Expressed in all Expressed in all epididymis: 519.8 TSPAN31 SAS ENSG00000135452 Tetraspanin 31 12 57738013-57750211 Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA057489 Approved Renal cancer:9.91e-5 (favourable), Head and neck cancer:1.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 73.1 TSPAN33 MGC50844, Penumbra ENSG00000158457 Tetraspanin 33 7 129144892-129169697 Predicted membrane proteins, Transporters Evidence at protein level HPA020357 Approved Approved Microtubules Renal cancer:8.74e-5 (favourable), Pancreatic cancer:8.88e-4 (favourable) Expressed in all Expressed in all kidney: 126.4 TSPAN4 NAG-2, TETRASPAN, TM4SF7, TSPAN-4 ENSG00000214063 Tetraspanin 4 11 842808-867116 Predicted membrane proteins Evidence at protein level Liver cancer:1.02e-4 (unfavourable), Glioma:2.57e-4 (unfavourable) Expressed in all Expressed in all spleen: 107.3 TSPO BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS ENSG00000100300 Translocator protein (18kDa) 22 43151514-43163242 Cancer-related genes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB011232, HPA046260 Uncertain Approved Vesicles
Mitochondria
Cytosol Liver cancer:1.61e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 301.2 TSPYL1 TSPYL ENSG00000189241 TSPY-like 1 6 116276578-116279903 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031970, HPA031971 Approved Supported Nucleus
Nucleoli Renal cancer:1.48e-13 (favourable), Pancreatic cancer:5.40e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 192.5 TSPYL2 CDA1, CINAP, CTCL, DENTT, HRIHFB2216, SE20-4, TSPX ENSG00000184205 TSPY-like 2 X 53082367-53088540 Predicted intracellular proteins Evidence at protein level HPA044133 Approved Pancreatic cancer:6.74e-8 (favourable), Renal cancer:8.16e-7 (unfavourable), Colorectal cancer:3.23e-4 (unfavourable) Expressed in all Expressed in all ovary: 144.1 TSPYL4 dJ486I3.2, KIAA0721 ENSG00000187189 TSPY-like 4 6 116249961-116254140 Predicted intracellular proteins Evidence at protein level HPA044863 Approved Renal cancer:5.13e-7 (favourable), Pancreatic cancer:8.46e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 121.1 TSR1 FLJ10534 ENSG00000167721 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 17 2322503-2337507 Predicted intracellular proteins Evidence at protein level HPA024434, HPA053087 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 28.7 TSR2 DT1P1A10, RP1-112K5.2, WGG1 ENSG00000158526 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) X 54440401-54445487 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA030514 Approved Approved Nucleus
Nucleoli
Cell Junctions
Cytosol Renal cancer:1.21e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 88.7 TSR3 C16orf42, MGC24381 ENSG00000007520 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) 16 1349240-1351911 Predicted intracellular proteins Evidence at protein level HPA040760, HPA046265 Uncertain Approved Golgi apparatus
Cytosol Expressed in all Expressed in all cerebral cortex: 36.8 TSSC1 ENSG00000032389 Tumor suppressing subtransferable candidate 1 2 3188925-3377882 Predicted intracellular proteins Evidence at protein level HPA031231, HPA031232, HPA031233, HPA031234 Approved Supported Nucleus
Nucleoli
Intermediate filaments Liver cancer:3.67e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 34.7 TSSC4 ENSG00000184281 Tumor suppressing subtransferable candidate 4 11 2400488-2403878 Predicted intracellular proteins Evidence at protein level HPA041801, HPA058763 Approved Approved Nucleoplasm
Cytosol Liver cancer:9.91e-4 (unfavourable) Expressed in all Expressed in all testis: 56.6 TST RDS ENSG00000128311 Thiosulfate sulfurtransferase (rhodanese) 22 37010859-37020183 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003044, HPA003643, CAB009546 Supported Supported Mitochondria Renal cancer:7.59e-6 (favourable), Urothelial cancer:1.04e-4 (favourable) Expressed in all Expressed in all colon: 146.0 TSTA3 FX, P35B, SDR4E1 ENSG00000104522 Tissue specific transplantation antigen P35B 8 143612618-143618048 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023361 Approved Approved Nucleoplasm
Cytosol Renal cancer:1.59e-4 (unfavourable), Ovarian cancer:2.41e-4 (favourable) Expressed in all Expressed in all stomach: 50.8 TSTD1 KAT ENSG00000215845 Thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 1 161037631-161038990 Predicted intracellular proteins Evidence at protein level HPA006518, HPA006655 Approved Approved Cytosol
Cytoplasmic bodies Expressed in all Expressed in all thyroid gland: 146.2 TSTD2 C9orf97, PP4189 ENSG00000136925 Thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 9 97600080-97633575 Predicted intracellular proteins Evidence at protein level HPA022537, HPA024241, HPA064304 Uncertain Approved Nucleoplasm Renal cancer:5.75e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 15.6 TTC1 TPR1 ENSG00000113312 Tetratricopeptide repeat domain 1 5 160009113-160065543 Predicted intracellular proteins Evidence at protein level HPA036557, HPA057502 Approved Validated Cytosol Liver cancer:1.71e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 80.6 TTC12 FLJ13859, FLJ20535, TPARM ENSG00000149292 Tetratricopeptide repeat domain 12 11 113314529-113383544 Predicted intracellular proteins Evidence at protein level HPA038542, HPA038543, HPA061364 Approved Approved Nucleoplasm Endometrial cancer:2.48e-5 (favourable), Renal cancer:5.95e-5 (favourable), Colorectal cancer:3.14e-4 (favourable) Expressed in all Expressed in all testis: 91.9 TTC13 FLJ22584 ENSG00000143643 Tetratricopeptide repeat domain 13 1 230906243-230978875 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA018022, HPA051558 Uncertain Approved Nucleoplasm Renal cancer:1.60e-11 (unfavourable), Pancreatic cancer:4.59e-5 (favourable), Head and neck cancer:7.66e-4 (favourable) Expressed in all Expressed in all lymph node: 23.3 TTC14 FLJ00166, KIAA1980 ENSG00000163728 Tetratricopeptide repeat domain 14 3 180602130-180617828 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA009295 Uncertain Supported Nucleus Expressed in all Expressed in all parathyroid gland: 59.7 TTC17 FLJ10890 ENSG00000052841 Tetratricopeptide repeat domain 17 11 43358932-43494933 Predicted intracellular proteins Evidence at protein level HPA038508 Approved Supported Plasma membrane
Cytosol Renal cancer:4.75e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.6 TTC19 FLJ20343, MGC19520 ENSG00000011295 Tetratricopeptide repeat domain 19 17 15999380-16045015 Disease related genes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA023010, HPA052380 Approved Validated Mitochondria Renal cancer:5.67e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.8 TTC21B FLJ11457, IFT139B, JBTS11, NPHP12, THM1 ENSG00000123607 Tetratricopeptide repeat domain 21B 2 165857475-165953843 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA035494, HPA035495 Uncertain Supported Mitochondria Renal cancer:1.36e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 14.3 TTC27 FLJ20272 ENSG00000018699 Tetratricopeptide repeat domain 27 2 32628032-32821051 Predicted intracellular proteins Evidence at protein level HPA031246 Approved Approved Nucleoli
Mitochondria Liver cancer:1.42e-5 (unfavourable), Renal cancer:7.32e-4 (unfavourable) Expressed in all Expressed in all testis: 24.9 TTC3 DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII ENSG00000182670 Tetratricopeptide repeat domain 3 21 37073226-37203112 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016810, HPA023964, HPA036304 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all thyroid gland: 107.0 TTC32 ENSG00000183891 Tetratricopeptide repeat domain 32 2 19896643-19901986 Predicted intracellular proteins Evidence at protein level HPA036024 Approved Approved Nucleoplasm
Mitochondria Renal cancer:5.45e-6 (unfavourable), Lung cancer:9.44e-4 (favourable) Expressed in all Expressed in all epididymis: 36.4 TTC37 KIAA0372, THES ENSG00000198677 Tetratricopeptide repeat domain 37 5 95463895-95555007 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037905 Approved Supported Nucleoplasm
Cytosol Colorectal cancer:2.62e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 80.8 TTC38 FLJ20699 ENSG00000075234 Tetratricopeptide repeat domain 38 22 46267961-46294008 Predicted intracellular proteins Evidence at protein level HPA029302 Approved Approved Cytosol Endometrial cancer:3.21e-6 (favourable) Expressed in all Expressed in all small intestine: 90.1 TTC39C C18orf17, FLJ33761, HsT2697 ENSG00000168234 Tetratricopeptide repeat domain 39C 18 23992773-24135610 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA065705, HPA065713 Approved Approved Nucleoplasm Renal cancer:2.60e-5 (unfavourable), Breast cancer:1.48e-4 (favourable) Expressed in all Expressed in all liver: 47.6 TTC4 FLJ41930, MGC5097 ENSG00000243725 Tetratricopeptide repeat domain 4 1 54715822-54742657 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA041608, HPA042459 Approved Uncertain Nuclear speckles
Cytoplasmic bodies Expressed in all Expressed in all cervix, uterine: 13.2 TTC7B TTC7L1 ENSG00000165914 Tetratricopeptide repeat domain 7B 14 90524564-90816479 Predicted intracellular proteins Evidence at protein level HPA058363, HPA059577 Supported Supported Plasma membrane Renal cancer:3.20e-6 (favourable) Mixed Expressed in all cerebral cortex: 72.8 TTC8 BBS8, RP51 ENSG00000165533 Tetratricopeptide repeat domain 8 14 88824153-88881078 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA003310 Uncertain Endometrial cancer:1.69e-5 (favourable), Renal cancer:4.89e-4 (favourable), Ovarian cancer:7.77e-4 (favourable) Expressed in all Expressed in all ovary: 90.7 TTC9C MGC29649 ENSG00000162222 Tetratricopeptide repeat domain 9C 11 62728069-62740293 Predicted intracellular proteins Evidence at protein level HPA055169 Approved Approved Nucleoplasm Renal cancer:4.67e-7 (unfavourable), Stomach cancer:4.15e-5 (favourable) Expressed in all Expressed in all thyroid gland: 30.9 TTF1 ENSG00000125482 Transcription termination factor, RNA polymerase I 9 132375548-132406851 Predicted intracellular proteins Evidence at protein level HPA054837 Supported Supported Nucleus
Nucleoli Liver cancer:1.40e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 18.2 TTI1 KIAA0406, smg-10 ENSG00000101407 TELO2 interacting protein 1 20 37983007-38033468 Predicted intracellular proteins Evidence at protein level CAB034230, HPA068338 Uncertain Approved Nucleoplasm
Vesicles Liver cancer:2.40e-7 (unfavourable), Endometrial cancer:3.30e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 20.6 TTLL12 KIAA0153 ENSG00000100304 Tubulin tyrosine ligase-like family member 12 22 43166622-43187133 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003054, CAB046029 Approved Approved Plasma membrane
Cytosol Liver cancer:2.84e-4 (unfavourable) Expressed in all Expressed in all esophagus: 74.6 TTLL3 DKFZP434B103, HOTTL ENSG00000214021 Tubulin tyrosine ligase-like family member 3 3 9808086-9855138 Predicted intracellular proteins Evidence at protein level HPA051413 Approved Renal cancer:6.45e-6 (unfavourable), Urothelial cancer:9.51e-6 (favourable) Mixed Expressed in all testis: 53.2 TTLL4 KIAA0173 ENSG00000135912 Tubulin tyrosine ligase-like family member 4 2 218710845-218755416 Predicted intracellular proteins Evidence at protein level HPA027091, HPA050252 Approved Approved Mitochondria Renal cancer:6.63e-12 (unfavourable), Liver cancer:2.95e-5 (unfavourable) Expressed in all Expressed in all testis: 46.7 TTYH3 KIAA1691 ENSG00000136295 Tweety family member 3 7 2631951-2664802 Predicted membrane proteins Evidence at protein level HPA053520 Uncertain Liver cancer:2.53e-5 (unfavourable), Renal cancer:2.58e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 62.4 TUBA1A B-ALPHA-1, FLJ25113, TUBA3 ENSG00000167552 Tubulin, alpha 1a 12 49184796-49189324 Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB008686, HPA039247, HPA043684, HPA063394 Supported Validated Microtubules Renal cancer:2.90e-4 (unfavourable) Tissue enriched Expressed in all cerebral cortex: 1377.5 TUBA1B K-ALPHA-1 ENSG00000123416 Tubulin, alpha 1b 12 49127782-49131397 Predicted intracellular proteins Evidence at protein level CAB011513, HPA039247, HPA043684, HPA063394 Supported Supported Microtubules Renal cancer:2.85e-12 (unfavourable), Liver cancer:1.68e-7 (unfavourable), Breast cancer:5.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 1417.8 TUBA1C bcm948, MGC10851, MGC14580, TUBA6 ENSG00000167553 Tubulin, alpha 1c 12 49188736-49274603 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039247, HPA043684, HPA063394 Supported Supported Microtubules Liver cancer:8.48e-8 (unfavourable), Renal cancer:6.26e-7 (unfavourable), Pancreatic cancer:5.64e-6 (unfavourable), Colorectal cancer:7.37e-5 (favourable), Breast cancer:2.90e-4 (unfavourable), Lung cancer:6.85e-4 (unfavourable) Expressed in all Expressed in all esophagus: 312.5 TUBA4A FLJ30169, H2-ALPHA, TUBA1 ENSG00000127824 Tubulin, alpha 4a 2 219249711-219278170 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004621, CAB005887, HPA039247, HPA043684, HPA063394 Approved Validated Microtubules Liver cancer:4.54e-6 (unfavourable) Expressed in all Expressed in all skin: 181.9 TUBB M40, MGC16435, OK/SW-cl.56, Tubb5 ENSG00000196230 Tubulin, beta class I 6 30720201-30725426 Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005417, CAB012406, HPA043640, HPA046280 Supported Validated Microtubules Renal cancer:2.62e-8 (unfavourable), Liver cancer:5.97e-4 (unfavourable) Expressed in all Expressed in all ovary: 71.9 TUBB4B Beta2, TUBB2C ENSG00000188229 Tubulin, beta 4B class IVb 9 137241213-137243707 FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010880, HPA043640, HPA046280 Supported Validated Microtubules Thyroid cancer:6.36e-6 (favourable), Endometrial cancer:4.91e-4 (favourable), Liver cancer:9.98e-4 (unfavourable) Expressed in all Expressed in all testis: 787.0 TUBB6 HsT1601, MGC4083 ENSG00000176014 Tubulin, beta 6 class V 18 12307669-12344320 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA043640, HPA046280 Approved Approved Microtubules Renal cancer:1.22e-7 (unfavourable), Urothelial cancer:9.69e-4 (unfavourable) Expressed in all Expressed in all esophagus: 215.2 TUBD1 FLJ12709, TUBD ENSG00000108423 Tubulin, delta 1 17 59859482-59892945 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level CAB004609, HPA023980, HPA027090 Approved Validated Nucleoplasm
Cytosol Liver cancer:1.00e-5 (unfavourable), Colorectal cancer:2.04e-4 (favourable), Renal cancer:6.06e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 12.7 TUBE1 dJ142L7.2, FLJ22589, TUBE ENSG00000074935 Tubulin, epsilon 1 6 112070777-112087529 FDA approved drug targets, Predicted intracellular proteins Evidence at protein level HPA032073, HPA032074 Approved Expressed in all Expressed in all testis: 54.9 TUBG2 ENSG00000037042 Tubulin, gamma 2 17 42659305-42667006 Predicted intracellular proteins Evidence at protein level CAB011495 Approved Supported Microtubule organizing center Liver cancer:4.68e-5 (unfavourable), Renal cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 77.6 TUBGCP2 GCP2, SPBC97, Spc97p ENSG00000130640 Tubulin, gamma complex associated protein 2 10 133278630-133312337 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA037885 Approved Supported Nucleoplasm
Centrosome Expressed in all Expressed in all fallopian tube: 31.8 TUBGCP3 GCP3, SPBC98, Spc98p ENSG00000126216 Tubulin, gamma complex associated protein 3 13 112485005-112588167 Predicted intracellular proteins Evidence at protein level HPA043913 Approved Expressed in all Expressed in all testis: 33.1 TUBGCP4 76P, FLJ14797 ENSG00000137822 Tubulin, gamma complex associated protein 4 15 43369221-43409771 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043212 Approved Supported Centrosome Expressed in all Expressed in all parathyroid gland: 12.2 TUBGCP5 GCP5, KIAA1899 ENSG00000275835 Tubulin, gamma complex associated protein 5 15 22983192-23039673 Predicted intracellular proteins Evidence at protein level HPA039366, HPA040366 Supported Supported Centrosome
Cytosol Expressed in all Expressed in all testis: 24.5 TUBGCP6 DJ402G11.6, GCP6, KIAA1669 ENSG00000128159 Tubulin, gamma complex associated protein 6 22 50217689-50244992 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043928 Approved Urothelial cancer:3.18e-5 (favourable), Pancreatic cancer:5.75e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.6 TUFM EF-TuMT, EFTu ENSG00000178952 Tu translation elongation factor, mitochondrial 16 28842411-28846408 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018991, HPA024087, CAB075730, CAB075731 Supported Validated Mitochondria Renal cancer:2.69e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 160.0 TULP3 TUBL3 ENSG00000078246 Tubby like protein 3 12 2877223-2941140 Predicted intracellular proteins Evidence at protein level HPA015285, HPA018496 Uncertain Supported Nucleus
Nucleoli
Plasma membrane Liver cancer:7.97e-5 (unfavourable), Endometrial cancer:2.99e-4 (favourable), Renal cancer:7.18e-4 (unfavourable) Expressed in all Expressed in all ovary: 46.4 TUSC1 TSG-9 ENSG00000198680 Tumor suppressor candidate 1 9 25676389-25678440 Predicted intracellular proteins Evidence at protein level HPA051426 Approved Approved Nucleus
Vesicles Expressed in all Expressed in all testis: 16.5 TUSC2 C3orf11, FUS1, PAP, PDAP2 ENSG00000114383 Tumor suppressor candidate 2 3 50320027-50328251 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA030116 Approved Vesicles
Cytosol Renal cancer:8.70e-7 (favourable), Liver cancer:2.84e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 42.2 TUT1 FLJ21850, FLJ22267, FLJ22347, PAPD2, RBM21, TUTase ENSG00000149016 Terminal uridylyl transferase 1, U6 snRNA-specific 11 62575045-62592177 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069055, HPA071838 Supported Nucleus
Cytosol Colorectal cancer:9.51e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 17.3 TVP23B CGI-148, FAM18B, FAM18B1, YDR084C ENSG00000171928 Trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 17 18780995-18806714 Predicted membrane proteins Evidence at protein level HPA019585, HPA065603 Uncertain Approved Golgi apparatus Expressed in all Expressed in all thyroid gland: 78.3 TWF1 A6, PTK9 ENSG00000151239 Twinfilin actin binding protein 1 12 43793723-43806375 Predicted intracellular proteins Evidence at protein level HPA018116 Approved Validated Cytosol Liver cancer:1.53e-4 (unfavourable), Colorectal cancer:8.29e-4 (favourable) Expressed in all Expressed in all thyroid gland: 119.1 TWF2 A6r, A6RP, PTK9L ENSG00000247596 Twinfilin actin binding protein 2 3 52228610-52239260 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053874 Uncertain Supported Plasma membrane Expressed in all Expressed in all lymph node: 62.1 TWISTNB ENSG00000105849 TWIST neighbor 7 19695462-19709087 Predicted intracellular proteins, RNA polymerase related proteins Evidence at protein level HPA019071, HPA022416 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:1.85e-4 (unfavourable) Expressed in all Expressed in all endometrium: 19.6 TWSG1 TSG ENSG00000128791 Twisted gastrulation BMP signaling modulator 1 18 9334767-9402420 Predicted secreted proteins Evidence at protein level HPA014898 Uncertain Approved Centrosome
Cytosol Expressed in all Expressed in all smooth muscle: 115.0 TXLNA DKFZp451J0118 ENSG00000084652 Taxilin alpha 1 32179686-32198285 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA045383, HPA072477 Supported Approved Nucleoplasm
Centrosome
Cytosol Renal cancer:7.21e-7 (unfavourable), Liver cancer:1.57e-6 (unfavourable), Pancreatic cancer:8.69e-5 (favourable), Head and neck cancer:5.53e-4 (favourable), Breast cancer:6.24e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 48.0 TXLNG CXorf15, FIAT, FLJ11209, LSR5, MGC126621, MGC126625, TXLNGX ENSG00000086712 Taxilin gamma X 16786427-16844519 Predicted intracellular proteins Evidence at protein level HPA000297, HPA000841 Approved Approved Cytosol Liver cancer:6.33e-6 (unfavourable) Expressed in all Expressed in all adrenal gland: 20.9 TXN TRX ENSG00000136810 Thioredoxin 9 110243811-110256640 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB008678, HPA047478, HPA055752 Supported Validated Nucleus
Nucleoli
Cytosol Endometrial cancer:3.40e-6 (favourable) Expressed in all Expressed in all esophagus: 705.8 TXN2 MT-TRX ENSG00000100348 Thioredoxin 2 22 36467036-36482030 Predicted intracellular proteins Evidence at protein level HPA000994, CAB008681 Approved Validated Mitochondria Renal cancer:1.17e-6 (favourable), Prostate cancer:2.04e-4 (favourable) Expressed in all Expressed in all adrenal gland: 145.4 TXNDC11 EFP1 ENSG00000153066 Thioredoxin domain containing 11 16 11679080-11742878 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041174, HPA041390 Supported Supported Plasma membrane
Cytosol Endometrial cancer:2.12e-5 (favourable), Glioma:8.01e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 83.0 TXNDC12 AGR1, ERP18, ERP19, hAG-1, PDIA16, TLP19 ENSG00000117862 Thioredoxin domain containing 12 (endoplasmic reticulum) 1 52020131-52056171 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level Renal cancer:1.40e-12 (unfavourable), Liver cancer:1.28e-5 (unfavourable), Head and neck cancer:2.61e-4 (unfavourable), Colorectal cancer:4.44e-4 (favourable) Expressed in all Expressed in all fallopian tube: 49.3 TXNDC15 2310047H23Rik, C5orf14, FLJ22625 ENSG00000113621 Thioredoxin domain containing 15 5 134873803-134901525 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA015483 Approved Approved Golgi apparatus Renal cancer:1.44e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 83.7 TXNDC17 MGC14353, TRP14, TXNL5 ENSG00000129235 Thioredoxin domain containing 17 17 6640758-6644541 Predicted intracellular proteins Evidence at protein level HPA022931 Approved Renal cancer:1.15e-5 (unfavourable) Expressed in all Expressed in all esophagus: 70.2 TXNDC5 EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15 ENSG00000239264 Thioredoxin domain containing 5 (endoplasmic reticulum) 6 7881517-7910814 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA034677, HPA034678 Supported Approved Endoplasmic reticulum Renal cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all urinary bladder: 323.2 TXNDC9 APACD ENSG00000115514 Thioredoxin domain containing 9 2 99318982-99340702 Predicted intracellular proteins Evidence at protein level HPA031844, HPA031845, HPA031846 Approved Validated Cytosol Liver cancer:9.63e-7 (unfavourable), Head and neck cancer:4.31e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 36.2 TXNIP EST01027, HHCPA78, THIF, VDUP1 ENSG00000265972 Thioredoxin interacting protein 1 145992435-145996600 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA031085, HPA053694 Approved Approved Plasma membrane
Cytosol Expressed in all Expressed in all adipose tissue: 1573.3 TXNL1 TRP32, Txl, TXNL ENSG00000091164 Thioredoxin-like 1 18 56597208-56651600 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002828, HPA002829, CAB016446 Supported Supported Validated Cytosol Liver cancer:9.62e-6 (unfavourable), Ovarian cancer:6.26e-5 (favourable) Expressed in all Expressed in all thyroid gland: 333.1 TXNL4A DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD ENSG00000141759 Thioredoxin-like 4A 18 79970811-80033949 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041324 Approved Nucleus
Nuclear membrane
Cytosol Liver cancer:3.38e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 82.7 TXNL4B Dim2, DLP, FLJ20511 ENSG00000140830 Thioredoxin-like 4B 16 72044289-72094431 Predicted intracellular proteins Evidence at protein level HPA065865 Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 28.8 TXNRD1 GRIM-12, Trxr1, TXNR ENSG00000198431 Thioredoxin reductase 1 12 104215779-104350305 Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001395, CAB004607, CAB015834, HPA043871 Approved Supported Nucleus Liver cancer:1.12e-5 (unfavourable), Renal cancer:1.20e-5 (unfavourable) Expressed in all Expressed in all adrenal gland: 109.8 TXNRD2 TR, TR3, TRXR2 ENSG00000184470 Thioredoxin reductase 2 22 19875517-19941992 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002007, HPA003323 Supported Supported Mitochondria
Cytosol Renal cancer:1.10e-7 (favourable) Expressed in all Expressed in all adrenal gland: 34.4 TYK2 JTK1 ENSG00000105397 Tyrosine kinase 2 19 10350529-10380676 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005157 Uncertain Approved Cytosol Head and neck cancer:1.05e-5 (favourable), Pancreatic cancer:1.02e-4 (favourable), Urothelial cancer:4.16e-4 (favourable), Renal cancer:4.43e-4 (unfavourable), Endometrial cancer:9.62e-4 (favourable) Expressed in all Expressed in all spleen: 101.6 TYROBP DAP12, KARAP, PLO-SL, PLOSL ENSG00000011600 TYRO protein tyrosine kinase binding protein 19 35904401-35908295 Disease related genes, Predicted membrane proteins Evidence at protein level CAB009493, HPA041899 Supported Renal cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 387.8 TYW1 FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W ENSG00000198874 TRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 7 66995173-67239519 Enzymes, Predicted membrane proteins Evidence at protein level HPA013568, HPA014118, HPA015535, HPA043136, HPA047029, HPA047052, HPA052097 Approved Approved Nucleus
Nucleoli Ovarian cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 22.9 TYW3 C1orf171, FLJ40918 ENSG00000162623 TRNA-yW synthesizing protein 3 homolog (S. cerevisiae) 1 74733152-74766678 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029641 Approved Approved Plasma membrane
Cytosol Liver cancer:1.49e-7 (unfavourable) Expressed in all Expressed in all ovary: 32.6 U2AF1 RN, RNU2AF1, U2AF35, U2AFBP ENSG00000160201 U2 small nuclear RNA auxiliary factor 1 21 43092956-43107587 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044833, HPA052083 Supported Validated Nucleoplasm Not detected Expressed in all thyroid gland: 71.4 U2AF1L5 ENSG00000275895 U2 small nuclear RNA auxiliary factor 1-like 5 21 6484623-6499261 Predicted intracellular proteins Evidence at protein level HPA044833, HPA052083 Supported Uncertain Nucleoplasm Not detected Expressed in all tonsil: 103.0 U2AF2 U2AF65 ENSG00000063244 U2 small nuclear RNA auxiliary factor 2 19 55654146-55674715 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010910, HPA041943, HPA043562 Supported Validated Nucleoplasm
Nuclear speckles Liver cancer:1.54e-6 (unfavourable) Expressed in all Expressed in all lymph node: 139.1 U2SURP fSAPa, SR140 ENSG00000163714 U2 snRNP-associated SURP domain containing 3 142964497-143060546 Predicted intracellular proteins Evidence at protein level HPA037545, HPA037546, HPA061407 Supported Supported Nucleoplasm Renal cancer:8.86e-7 (unfavourable), Liver cancer:3.15e-5 (unfavourable), Urothelial cancer:6.78e-4 (favourable), Endometrial cancer:8.44e-4 (unfavourable), Pancreatic cancer:8.92e-4 (unfavourable) Expressed in all Expressed in all testis: 37.2 UAP1 AgX, AGX1, SPAG2 ENSG00000117143 UDP-N-acetylglucosamine pyrophosphorylase 1 1 162561506-162599842 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA014659 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:5.12e-5 (unfavourable) Expressed in all Expressed in all testis: 165.3 UBA1 A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X ENSG00000130985 Ubiquitin-like modifier activating enzyme 1 X 47190861-47215128 Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA000289, HPA001506, CAB019435, CAB073410 Approved Validated Nucleoplasm Liver cancer:6.10e-5 (unfavourable), Thyroid cancer:1.78e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 235.0 UBA2 ARX, FLJ13058, HRIHFB2115, SAE2 ENSG00000126261 Ubiquitin-like modifier activating enzyme 2 19 34428352-34471251 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA041436 Supported Supported Nucleoplasm Liver cancer:3.76e-4 (unfavourable), Renal cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all testis: 167.2 UBA3 hUba3, NAE2, UBE1C ENSG00000144744 Ubiquitin-like modifier activating enzyme 3 3 69054730-69080408 Predicted intracellular proteins Evidence at protein level HPA034873, HPA034874, HPA065335 Supported Approved Nucleoplasm
Plasma membrane
Centrosome
Cytosol Liver cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 68.1 UBA5 FLJ23251, UBE1DC1 ENSG00000081307 Ubiquitin-like modifier activating enzyme 5 3 132654446-132678097 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017235 Uncertain Validated Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 63.1 UBA52 CEP52, HUBCEP52, L40, MGC126879, MGC126881, MGC57125, RPL40 ENSG00000221983 Ubiquitin A-52 residue ribosomal protein fusion product 1 19 18571730-18577550 Predicted intracellular proteins, Ribosomal proteins Evidence at protein level HPA041344, HPA049132, HPA056624 Supported Approved Nucleoplasm
Endoplasmic reticulum
Plasma membrane
Cytosol Expressed in all Expressed in all ovary: 1909.1 UBA6 FLJ10808, UBE1L2 ENSG00000033178 Ubiquitin-like modifier activating enzyme 6 4 67612652-67701179 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037001 Uncertain Validated Nucleoplasm
Cytosol Renal cancer:7.01e-5 (unfavourable) Expressed in all Expressed in all testis: 18.6 UBA7 D8, UBA1B, UBE1L, UBE2 ENSG00000182179 Ubiquitin-like modifier activating enzyme 7 3 49805207-49813946 Plasma proteins, Predicted membrane proteins Evidence at protein level CAB015444, HPA058182 Approved Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:1.04e-5 (unfavourable), Urothelial cancer:1.48e-4 (favourable), Breast cancer:1.55e-4 (favourable) Expressed in all Expressed in all spleen: 66.5 UBAC1 GBDR1, UBADC1 ENSG00000130560 UBA domain containing 1 9 135932969-135961380 Predicted intracellular proteins Evidence at protein level HPA005651 Approved Supported Golgi apparatus
Plasma membrane
Cytosol Renal cancer:3.58e-7 (favourable), Cervical cancer:4.34e-6 (favourable) Expressed in all Expressed in all skeletal muscle: 88.7 UBAC2 FLJ30548, PHGDHL1, RP11-178C10.1 ENSG00000134882 UBA domain containing 2 13 99200774-99386434 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA013448 Approved Approved Cytosol Pancreatic cancer:1.73e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 35.6 UBALD1 FAM100A ENSG00000153443 UBA-like domain containing 1 16 4608883-4615027 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA066771 Approved Approved Nucleus
Cell Junctions
Cytosol Expressed in all Expressed in all cerebral cortex: 23.9 UBALD2 FAM100B, MGC29814 ENSG00000185262 UBA-like domain containing 2 17 76265202-76271299 Predicted intracellular proteins Evidence at protein level HPA023046 Uncertain Expressed in all Expressed in all bone marrow: 141.0 UBAP1 UBAP ENSG00000165006 Ubiquitin associated protein 1 9 34179005-34252523 Predicted intracellular proteins Evidence at protein level HPA019804, HPA041590 Approved Validated Plasma membrane
Cytosol Renal cancer:7.49e-6 (favourable) Expressed in all Expressed in all testis: 88.4 UBAP2 bA176F3.5, FLJ22435, KIAA1491 ENSG00000137073 Ubiquitin associated protein 2 9 33921693-34048949 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA021684 Approved Approved Cytosol Liver cancer:3.45e-6 (unfavourable), Renal cancer:1.95e-4 (favourable), Ovarian cancer:8.59e-4 (favourable) Expressed in all Expressed in all testis: 46.5 UBAP2L KIAA0144, NICE-4 ENSG00000143569 Ubiquitin associated protein 2-like 1 154220179-154271510 Predicted intracellular proteins Evidence at protein level HPA035068 Approved Approved Nuclear speckles
Cytosol Renal cancer:2.89e-5 (unfavourable), Liver cancer:4.65e-5 (unfavourable) Expressed in all Expressed in all testis: 122.8 UBB FLJ25987, MGC8385 ENSG00000170315 Ubiquitin B 17 16380798-16382745 Predicted intracellular proteins Evidence at protein level CAB013048, HPA041344, HPA049132 Supported Renal cancer:1.07e-4 (favourable) Expressed in all Expressed in all testis: 2227.1 UBC ENSG00000150991 Ubiquitin C 12 124911604-124917368 Predicted intracellular proteins Evidence at protein level CAB000362, CAB005419, HPA041344, HPA049132 Supported Approved Nuclear speckles Renal cancer:7.90e-7 (unfavourable) Expressed in all Expressed in all testis: 1956.0 UBE2A HHR6A, RAD6A, UBC2 ENSG00000077721 Ubiquitin-conjugating enzyme E2A X 119574467-119591083 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA003875, HPA051765, HPA065898 Supported Nucleoplasm
Vesicles
Plasma membrane
Cytosol Renal cancer:2.20e-6 (unfavourable), Cervical cancer:2.16e-4 (favourable), Head and neck cancer:9.07e-4 (unfavourable) Expressed in all Expressed in all placenta: 75.9 UBE2B HHR6B, RAD6B, UBC2 ENSG00000119048 Ubiquitin-conjugating enzyme E2B 5 134371179-134391992 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003875, HPA051765, HPA065898 Supported Nucleoplasm
Vesicles
Plasma membrane
Cytosol Expressed in all Expressed in all adrenal gland: 99.5 UBE2D1 E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A ENSG00000072401 Ubiquitin-conjugating enzyme E2D 1 10 58334975-58370753 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Renal cancer:8.04e-6 (unfavourable), Liver cancer:5.58e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 47.8 UBE2D2 UBC4, UbcH5B ENSG00000131508 Ubiquitin-conjugating enzyme E2D 2 5 139526431-139628433 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Liver cancer:9.63e-7 (unfavourable), Renal cancer:2.09e-5 (unfavourable), Colorectal cancer:5.09e-5 (favourable), Endometrial cancer:5.90e-4 (favourable) Expressed in all Expressed in all testis: 237.4 UBE2D3 UbcH5C ENSG00000109332 Ubiquitin-conjugating enzyme E2D 3 4 102794383-102868896 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003920 Uncertain Approved Plasma membrane
Cytosol Renal cancer:4.51e-4 (favourable) Expressed in all Expressed in all bone marrow: 301.5 UBE2D4 HBUCE1 ENSG00000078967 Ubiquitin-conjugating enzyme E2D 4 (putative) 7 43926438-43956136 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003920 Approved Approved Plasma membrane
Cytosol Pancreatic cancer:4.86e-4 (favourable), Prostate cancer:5.77e-4 (favourable), Renal cancer:6.51e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 12.6 UBE2E1 UbcH6 ENSG00000170142 Ubiquitin-conjugating enzyme E2E 1 3 23805903-23891316 Enzymes, Predicted intracellular proteins Evidence at protein level HPA030445, CAB073413 Approved Approved Nucleoplasm Liver cancer:9.97e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 119.1 UBE2E2 FLJ25157, UbcH8 ENSG00000182247 Ubiquitin-conjugating enzyme E2E 2 3 23203020-23591793 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003303, HPA028872, HPA030445, CAB073417 Approved Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 40.2 UBE2E3 UbcH9 ENSG00000170035 Ubiquitin-conjugating enzyme E2E 3 2 180967248-181076585 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003303, HPA030445 Approved Pancreatic cancer:1.78e-5 (unfavourable), Head and neck cancer:8.08e-5 (unfavourable), Liver cancer:9.11e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 129.1 UBE2F NCE2 ENSG00000184182 Ubiquitin-conjugating enzyme E2F (putative) 2 237966827-238042782 Predicted intracellular proteins Evidence at protein level HPA037444 Approved Approved Cytosol Renal cancer:1.59e-7 (unfavourable), Liver cancer:2.72e-4 (unfavourable) Expressed in all Expressed in all epididymis: 62.7 UBE2G1 UBC7, UBE2G ENSG00000132388 Ubiquitin-conjugating enzyme E2G 1 17 4269259-4366628 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045681, HPA050551 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all skeletal muscle: 73.2 UBE2G2 UBC7 ENSG00000184787 Ubiquitin-conjugating enzyme E2G 2 21 44768580-44802019 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003332 Approved Renal cancer:7.02e-5 (unfavourable) Expressed in all Expressed in all seminal vesicle: 26.2 UBE2H GID3, UBC8, UBCH ENSG00000186591 Ubiquitin-conjugating enzyme E2H 7 129830732-129952949 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003302 Approved Supported Mitochondria Pancreatic cancer:2.33e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 92.9 UBE2I UBC9 ENSG00000103275 Ubiquitin-conjugating enzyme E2I 16 1308880-1327018 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA003909, CAB009021 Approved Validated Cytosol Thyroid cancer:5.68e-4 (favourable), Liver cancer:7.50e-4 (unfavourable) Expressed in all Expressed in all ovary: 116.8 UBE2J1 CGI-76, HSPC153, NCUBE1, UBC6 ENSG00000198833 Ubiquitin-conjugating enzyme E2, J1 6 89326625-89352848 Enzymes, Predicted membrane proteins Evidence at protein level HPA003509, CAB073419 Supported Liver cancer:6.90e-5 (unfavourable), Renal cancer:1.11e-4 (unfavourable), Endometrial cancer:2.87e-4 (favourable), Ovarian cancer:7.43e-4 (favourable) Expressed in all Expressed in all lymph node: 103.6 UBE2J2 NCUBE2, Ubc6p ENSG00000160087 Ubiquitin-conjugating enzyme E2, J2 1 1253909-1273885 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:2.00e-4 (unfavourable) Expressed in all Expressed in all testis: 115.1 UBE2K HIP2, HYPG, UBC1 ENSG00000078140 Ubiquitin-conjugating enzyme E2K 4 39698044-39782792 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028869, CAB033212, CAB033515 Supported Approved Actin filaments
Cytosol Pancreatic cancer:8.60e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 64.9 UBE2L3 UBCH7 ENSG00000185651 Ubiquitin-conjugating enzyme E2L 3 22 21549447-21624034 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045609, HPA062415 Approved Supported Nucleus
Cytosol Ovarian cancer:3.82e-6 (favourable), Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 67.4 UBE2L6 UBCH8 ENSG00000156587 Ubiquitin-conjugating enzyme E2L 6 11 57551656-57568284 Enzymes, Predicted intracellular proteins Evidence at protein level HPA003328, CAB073407 Supported Approved Cytosol Pancreatic cancer:4.88e-4 (unfavourable), Breast cancer:6.75e-4 (favourable) Expressed in all Expressed in all spleen: 150.4 UBE2M hUbc12, UBC12 ENSG00000130725 Ubiquitin-conjugating enzyme E2M 19 58555712-58558960 Predicted intracellular proteins Evidence at protein level CAB004993, HPA054551, HPA057800 Approved Supported Nucleus
Nuclear bodies
Cytosol Expressed in all Expressed in all cerebral cortex: 108.3 UBE2N MGC8489, UBC13, UbcH-ben ENSG00000177889 Ubiquitin-conjugating enzyme E2N 12 93405673-93442262 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044976 Approved Supported Nucleus
Nucleoli fibrillar center Liver cancer:2.41e-4 (unfavourable) Expressed in all Expressed in all testis: 252.8 UBE2O E2-230K ENSG00000175931 Ubiquitin-conjugating enzyme E2O 17 76389451-76453206 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023605 Uncertain Supported Nucleus
Nuclear bodies Renal cancer:4.34e-9 (unfavourable), Liver cancer:6.84e-8 (unfavourable) Expressed in all Expressed in all cerebral cortex: 36.1 UBE2Q1 NICE-5, PRO3094, UBE2Q ENSG00000160714 Ubiquitin-conjugating enzyme E2Q family member 1 1 154548577-154559028 Enzymes, Predicted intracellular proteins Evidence at protein level HPA063368 Approved Approved Nucleoplasm
Centrosome Renal cancer:4.84e-7 (unfavourable), Thyroid cancer:1.86e-5 (favourable), Liver cancer:8.74e-4 (unfavourable) Expressed in all Expressed in all testis: 56.8 UBE2Q2 DKFZp762C143 ENSG00000140367 Ubiquitin-conjugating enzyme E2Q family member 2 15 75843285-75901078 Enzymes, Predicted intracellular proteins Evidence at protein level Ovarian cancer:5.73e-4 (favourable) Expressed in all Expressed in all thyroid gland: 51.3 UBE2R2 CDC34B, FLJ20419, MGC10481, UBC3B ENSG00000107341 Ubiquitin-conjugating enzyme E2R 2 9 33817567-33920404 Enzymes, Predicted intracellular proteins Evidence at protein level HPA061000 Approved Nucleus
Nucleoli Liver cancer:4.37e-4 (unfavourable) Expressed in all Expressed in all testis: 68.5 UBE2S E2-EPF ENSG00000108106 Ubiquitin-conjugating enzyme E2S 19 55399745-55407777 Enzymes, Predicted intracellular proteins Evidence at protein level CAB015228, HPA057150 Approved Approved Nucleoplasm
Plasma membrane Renal cancer:8.16e-8 (unfavourable), Liver cancer:8.00e-6 (unfavourable), Endometrial cancer:2.05e-4 (unfavourable) Expressed in all Expressed in all testis: 120.1 UBE2V1 CROC-1, CROC1, UBE2V, UEV-1, UEV1A ENSG00000244687 Ubiquitin-conjugating enzyme E2 variant 1 20 50081124-50115959 Predicted intracellular proteins Evidence at protein level HPA052535, HPA053186 Validated Nucleoplasm Renal cancer:4.58e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 110.0 UBE2V2 DDVit-1, EDPF-1, MMS2, UEV-2 ENSG00000169139 Ubiquitin-conjugating enzyme E2 variant 2 8 48008400-48064708 Predicted intracellular proteins Evidence at protein level HPA052535, HPA053186 Supported Nucleoplasm Renal cancer:4.96e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 97.9 UBE2W FLJ11011 ENSG00000104343 Ubiquitin-conjugating enzyme E2W (putative) 8 73780097-73878910 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045161, HPA073181 Uncertain Supported Nucleoli Expressed in all Expressed in all testis: 19.7 UBE2Z FLJ13855, USE1 ENSG00000159202 Ubiquitin-conjugating enzyme E2Z 17 48908369-48929056 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007922 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.05e-4 (unfavourable), Colorectal cancer:4.62e-4 (favourable), Liver cancer:5.57e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.4 UBE3A ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A ENSG00000114062 Ubiquitin protein ligase E3A 15 25333728-25439056 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB009723, HPA039410, HPA040380 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 88.7 UBE3B ENSG00000151148 Ubiquitin protein ligase E3B 12 109477402-109536705 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041012 Approved Approved Nuclear speckles
Mitochondria Renal cancer:2.49e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 33.4 UBE3C KIAA0010, KIAA10 ENSG00000009335 Ubiquitin protein ligase E3C 7 157138913-157269372 Predicted intracellular proteins Evidence at protein level HPA039915 Approved Approved Nucleoplasm
Plasma membrane
Mitochondria Renal cancer:9.18e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 50.2 UBE4A E4, KIAA0126, UBOX2, UFD2 ENSG00000110344 Ubiquitination factor E4A 11 118359585-118399211 Predicted intracellular proteins Evidence at protein level HPA055035, HPA064010 Approved Supported Nuclear speckles Expressed in all Expressed in all parathyroid gland: 42.9 UBE4B E4, KIAA0684, UBOX3, UFD2 ENSG00000130939 Ubiquitination factor E4B 1 10032832-10181239 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019219 Approved Liver cancer:3.69e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 42.7 UBFD1 FLJ38870, FLJ42145, UBPH ENSG00000103353 Ubiquitin family domain containing 1 16 23557362-23574389 Predicted intracellular proteins Evidence at protein level HPA051746 Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 55.5 UBIAD1 SCCD, TERE1 ENSG00000120942 UbiA prenyltransferase domain containing 1 1 11273206-11296049 Disease related genes, Predicted membrane proteins Evidence at protein level HPA044862 Approved Vesicles Renal cancer:6.80e-5 (favourable) Expressed in all Expressed in all fallopian tube: 15.7 UBL3 DKFZP434K151, FLJ32018, HCG-1, PNSC1 ENSG00000122042 Ubiquitin-like 3 13 29764371-29850684 Predicted intracellular proteins Evidence at protein level HPA053772, HPA058781 Uncertain Approved Centrosome Renal cancer:4.23e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 90.9 UBL4A DXS254E, GDX, GET5, MDY2, TMA24, UBL4 ENSG00000102178 Ubiquitin-like 4A X 154483717-154486670 Predicted intracellular proteins Evidence at protein level HPA003617 Approved Liver cancer:8.64e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 31.8 UBL5 ENSG00000198258 Ubiquitin-like 5 19 9827892-9830115 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all epididymis: 572.1 UBL7 BMSC-UbP, MGC14421 ENSG00000138629 Ubiquitin-like 7 15 74445977-74461182 Predicted intracellular proteins Evidence at protein level HPA040423, HPA041897 Approved Approved Nucleoplasm
Cytosol Cervical cancer:6.37e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 75.0 UBLCP1 CPUB1, MGC10067 ENSG00000164332 Ubiquitin-like domain containing CTD phosphatase 1 5 159263081-159286040 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039615 Approved Validated Nucleus
Nucleoli Liver cancer:4.46e-5 (unfavourable) Expressed in all Expressed in all testis: 49.8 UBN1 ENSG00000118900 Ubinuclein 1 16 4846665-4882360 Predicted intracellular proteins Evidence at protein level HPA061029, HPA069045 Supported Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all testis: 70.3 UBOX5 KIAA0860, RNF37, Ubce7ip5, UIP5 ENSG00000185019 U-box domain containing 5 20 3107573-3160196 Predicted intracellular proteins Evidence at protein level HPA028871 Approved Approved Nucleoplasm Pancreatic cancer:1.80e-5 (favourable), Head and neck cancer:4.52e-5 (favourable) Expressed in all Expressed in all fallopian tube: 7.1 UBP1 LBP-1a ENSG00000153560 Upstream binding protein 1 (LBP-1a) 3 33388336-33441371 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003967 Supported Nucleoplasm Colorectal cancer:1.81e-4 (favourable), Liver cancer:9.45e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 53.9 UBQLN1 DA41, DSK2, PLIC-1, XDRP1 ENSG00000135018 Ubiquilin 1 9 83659963-83708203 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB037256, HPA054143 Supported Supported Nucleoplasm
Cytosol Renal cancer:1.07e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 114.1 UBQLN2 Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157 ENSG00000188021 Ubiquilin 2 X 56563639-56567868 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006431, CAB013481 Supported Validated Plasma membrane
Cytosol Liver cancer:2.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 53.9 UBQLN4 A1U, C1orf6, UBIN ENSG00000160803 Ubiquilin 4 1 156035301-156053794 Predicted intracellular proteins, Transporters Evidence at protein level HPA061797 Approved Supported Nucleus Expressed in all Expressed in all cerebral cortex: 41.2 UBR1 ENSG00000159459 Ubiquitin protein ligase E3 component n-recognin 1 15 42942897-43106113 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038838 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all parathyroid gland: 26.9 UBR2 bA49A4.1, C6orf133, dJ392M17.3, KIAA0349 ENSG00000024048 Ubiquitin protein ligase E3 component n-recognin 2 6 42564062-42693504 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027869, HPA027880 Approved Approved Nucleoplasm
Plasma membrane Ovarian cancer:1.65e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 30.0 UBR3 DKFZp434P117, FLJ37422, KIAA2024, ZNF650 ENSG00000144357 Ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 169827458-170084131 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA035390 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all parathyroid gland: 38.9 UBR4 KIAA0462, KIAA1307, RBAF600, ZUBR1 ENSG00000127481 Ubiquitin protein ligase E3 component n-recognin 4 1 19074506-19210276 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA013394, HPA021046 Approved Supported Nucleoplasm
Centrosome
Cytosol Expressed in all Expressed in all skin: 90.6 UBR5 DD5, EDD, EDD1, HYD, KIAA0896 ENSG00000104517 Ubiquitin protein ligase E3 component n-recognin 5 8 102253012-102412841 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA053688 Supported Nucleoplasm
Cytosol Liver cancer:1.26e-4 (unfavourable) Expressed in all Expressed in all testis: 79.7 UBR7 C14orf130 ENSG00000012963 Ubiquitin protein ligase E3 component n-recognin 7 (putative) 14 93207056-93229215 Predicted intracellular proteins Evidence at protein level HPA000861 Approved Approved Nucleus Liver cancer:8.12e-5 (unfavourable), Renal cancer:9.76e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 22.8 UBTF NOR-90, UBF, UBF1, UBF2 ENSG00000108312 Upstream binding transcription factor, RNA polymerase I 17 44205033-44221626 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB004611, HPA006385 Supported Supported Validated Nucleoli fibrillar center Expressed in all Expressed in all lymph node: 82.3 UBXN1 2B28, LOC51035, SAKS1, UBXD10 ENSG00000162191 UBX domain protein 1 11 62676498-62679117 Predicted intracellular proteins Evidence at protein level HPA012669 Approved Approved Nucleoplasm Expressed in all Expressed in all ovary: 145.7 UBXN11 SOC, SOCI, UBXD5 ENSG00000158062 UBX domain protein 11 1 26281328-26318363 Predicted intracellular proteins Evidence at protein level HPA028600, HPA031357 Approved Approved Nucleoli
Cytosol Liver cancer:5.90e-6 (unfavourable), Cervical cancer:2.54e-5 (favourable), Endometrial cancer:1.90e-4 (favourable), Head and neck cancer:4.90e-4 (favourable) Expressed in all Expressed in all fallopian tube: 49.6 UBXN2B p37 ENSG00000215114 UBX domain protein 2B 8 58411264-58451501 Predicted intracellular proteins Evidence at protein level HPA045278 Uncertain Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 26.5 UBXN4 KIAA0242, UBXD2, UBXDC1 ENSG00000144224 UBX domain protein 4 2 135741619-135785055 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036325 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 104.6 UBXN6 UBXD1, UBXDC2 ENSG00000167671 UBX domain protein 6 19 4444999-4457822 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040906, HPA041313, HPA061872 Approved Approved Golgi apparatus
Cytosol Renal cancer:2.78e-5 (favourable), Endometrial cancer:5.68e-5 (favourable), Pancreatic cancer:6.95e-4 (favourable) Expressed in all Expressed in all testis: 139.2 UBXN7 KIAA0794, UBXD7 ENSG00000163960 UBX domain protein 7 3 196347662-196432474 Predicted intracellular proteins Evidence at protein level HPA048441, HPA049442 Supported Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 22.3 UBXN8 D8S2298E, REP8, UBXD6 ENSG00000104691 UBX domain protein 8 8 30732247-30767006 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA017725, HPA077538 Approved Supported Nucleoli
Endoplasmic reticulum Renal cancer:5.25e-5 (unfavourable), Colorectal cancer:6.13e-4 (favourable) Expressed in all Expressed in all ovary: 109.4 UCHL3 ENSG00000118939 Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 13 75549480-75606020 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019678, CAB037139, CAB037208 Approved Supported Nucleus
Cytosol Liver cancer:6.41e-4 (unfavourable) Expressed in all Expressed in all testis: 90.1 UCHL5 CGI-70, INO80R, UCH37 ENSG00000116750 Ubiquitin carboxyl-terminal hydrolase L5 1 193012250-193060080 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005908, HPA006069, HPA075383 Approved Approved Approved Nucleoplasm
Mitochondria Thyroid cancer:7.10e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.1 UCK1 FLJ12255, URK1 ENSG00000130717 Uridine-cytidine kinase 1 9 131523801-131531268 Enzymes, Predicted intracellular proteins Evidence at protein level HPA050969 Approved Approved Nucleus Renal cancer:2.21e-7 (favourable), Cervical cancer:3.19e-4 (favourable) Expressed in all Expressed in all thyroid gland: 31.1 UCK2 UMPK ENSG00000143179 Uridine-cytidine kinase 2 1 165827531-165911618 Enzymes, Predicted intracellular proteins Evidence at protein level HPA057128 Approved Nucleus Renal cancer:5.12e-13 (unfavourable), Liver cancer:9.22e-8 (unfavourable), Lung cancer:4.98e-4 (unfavourable), Melanoma:6.70e-4 (unfavourable) Expressed in all Expressed in all placenta: 41.0 UCKL1 FLJ20517, URKL1 ENSG00000198276 Uridine-cytidine kinase 1-like 1 20 63939829-63956415 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004722, HPA004769 Approved Approved Endoplasmic reticulum Pancreatic cancer:4.42e-4 (favourable) Expressed in all Expressed in all spleen: 40.9 UCP2 BMIQ4, SLC25A8 ENSG00000175567 Uncoupling protein 2 (mitochondrial, proton carrier) 11 73974667-73983307 Predicted intracellular proteins, Transporters Evidence at protein level CAB025583 Approved Renal cancer:7.80e-6 (unfavourable), Cervical cancer:4.65e-5 (favourable) Expressed in all Expressed in all lymph node: 391.2 UEVLD Attp, UEV3 ENSG00000151116 UEV and lactate/malate dehyrogenase domains 11 18529609-18588747 Predicted intracellular proteins Evidence at protein level HPA047134 Approved Approved Nucleus
Cytosol Colorectal cancer:7.07e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.5 UFC1 HSPC155 ENSG00000143222 Ubiquitin-fold modifier conjugating enzyme 1 1 161152776-161158856 Predicted intracellular proteins Evidence at protein level HPA027481, HPA028722 Approved Approved Nuclear speckles
Cytosol Renal cancer:2.62e-6 (unfavourable) Expressed in all Expressed in all fallopian tube: 250.5 UFD1L UFD1 ENSG00000070010 Ubiquitin fusion degradation 1 like (yeast) 22 19449910-19479215 Predicted intracellular proteins, Transporters Evidence at protein level HPA030287, HPA030288, HPA073425 Approved Validated Endoplasmic reticulum Renal cancer:4.50e-8 (unfavourable), Liver cancer:2.59e-4 (unfavourable) Expressed in all Expressed in all testis: 64.5 UFL1 KIAA0776, Maxer, NLBP, RCAD ENSG00000014123 UFM1-specific ligase 1 6 96521595-96555276 Predicted intracellular proteins Evidence at protein level HPA030558, HPA030559, HPA030560 Supported Supported Endoplasmic reticulum Expressed in all Expressed in all thyroid gland: 46.9 UFM1 bA131P10.1, C13orf20 ENSG00000120686 Ubiquitin-fold modifier 1 13 38349849-38363619 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039758 Approved Head and neck cancer:1.08e-4 (unfavourable), Endometrial cancer:9.35e-4 (favourable) Expressed in all Expressed in all endometrium: 101.0 UFSP2 C4orf20, FLJ11200 ENSG00000109775 UFM1-specific peptidase 2 4 185399540-185425985 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039985, HPA043298 Approved Approved Nucleus
Cytosol Renal cancer:1.07e-8 (favourable) Expressed in all Expressed in all thyroid gland: 53.8 UGCG GCS ENSG00000148154 UDP-glucose ceramide glucosyltransferase 9 111896766-111935369 Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA024124 Approved Endometrial cancer:4.44e-5 (favourable), Cervical cancer:6.62e-4 (favourable) Expressed in all Expressed in all adrenal gland: 84.4 UGDH ENSG00000109814 UDP-glucose 6-dehydrogenase 4 39498755-39528311 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB034444, HPA036656, HPA036657 Supported Validated Nucleoplasm Renal cancer:5.51e-10 (unfavourable) Expressed in all Expressed in all colon: 97.7 UGGT1 HUGT1, UGCGL1 ENSG00000136731 UDP-glucose glycoprotein glucosyltransferase 1 2 128091200-128195677 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012761, HPA015127 Supported Uncertain Cytosol Renal cancer:6.37e-4 (unfavourable) Expressed in all Expressed in all epididymis: 23.8 UGP2 UGP1, UGPP1 ENSG00000169764 UDP-glucose pyrophosphorylase 2 2 63840940-63891562 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034696, HPA034697, HPA064836 Supported Approved Nucleoplasm
Centrosome
Mitochondria Liver cancer:2.50e-5 (favourable) Expressed in all Expressed in all liver: 450.1 UHMK1 KIS, Kist ENSG00000152332 U2AF homology motif (UHM) kinase 1 1 162497251-162529629 Enzymes, Predicted intracellular proteins Evidence at protein level HPA071190 Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 43.4 UHRF1BP1 C6orf107, dJ349A12.1, FLJ20302, ICBP90 ENSG00000065060 UHRF1 binding protein 1 6 34792015-34883138 Predicted intracellular proteins Evidence at protein level HPA032099, HPA032100 Uncertain Approved Nucleoplasm
Nuclear membrane
Cytosol Liver cancer:3.86e-4 (unfavourable) Expressed in all Expressed in all testis: 22.4 UHRF2 MGC33463, NIRF, RNF107, TDRD23, URF2 ENSG00000147854 Ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 9 6413151-6507054 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA026633, HPA026697 Validated Nucleoplasm Expressed in all Expressed in all bone marrow: 32.9 UIMC1 RAP80 ENSG00000087206 Ubiquitin interaction motif containing 1 5 176905005-177022633 Predicted intracellular proteins Evidence at protein level HPA037503, HPA037504 Approved Validated Nuclear bodies Liver cancer:7.67e-6 (unfavourable) Expressed in all Expressed in all testis: 109.1 ULK1 ATG1, ATG1A ENSG00000177169 Unc-51 like autophagy activating kinase 1 12 131894651-131923167 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA063990 Approved Cytosol Expressed in all Expressed in all skin: 23.7 ULK2 ATG1B, KIAA0623, Unc51.2 ENSG00000083290 Unc-51 like autophagy activating kinase 2 17 19770829-19867936 Enzymes, Predicted intracellular proteins Evidence at protein level HPA009027, CAB037021 Approved Expressed in all Expressed in all testis: 65.7 ULK3 DKFZP434C131, FLJ90566 ENSG00000140474 Unc-51 like kinase 3 15 74836116-74843346 Enzymes, Predicted intracellular proteins Evidence at protein level HPA040474 Approved Pancreatic cancer:7.47e-4 (favourable) Expressed in all Expressed in all esophagus: 28.6 UNC119 HRG4, POC7, POC7A ENSG00000109103 Unc-119 lipid binding chaperone 17 28546707-28552668 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041912 Supported Pancreatic cancer:8.09e-5 (favourable), Melanoma:2.38e-4 (unfavourable), Thyroid cancer:9.82e-4 (unfavourable) Expressed in all Expressed in all testis: 45.4 UNC119B MGC5139, POC7B ENSG00000175970 Unc-119 lipid binding chaperone B 12 120710435-120723640 Predicted intracellular proteins Evidence at protein level Renal cancer:6.69e-10 (favourable), Pancreatic cancer:1.26e-4 (favourable) Expressed in all Expressed in all fallopian tube: 74.9 UNC45A GC-UNC45, SMAP-1 ENSG00000140553 Unc-45 myosin chaperone A 15 90930180-90954093 Predicted intracellular proteins Evidence at protein level HPA039228 Approved Supported Nuclear speckles
Cytosol Renal cancer:7.46e-7 (favourable), Liver cancer:7.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 48.5 UNC50 GMH1, UNCL, URP ENSG00000115446 Unc-50 homolog (C. elegans) 2 98608579-98618515 Predicted membrane proteins Evidence at protein level HPA027009 Approved Liver cancer:4.89e-5 (unfavourable), Breast cancer:4.79e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 105.7 UNG DGU, HIGM4, UDG, UNG1, UNG2 ENSG00000076248 Uracil DNA glycosylase 12 109097574-109110992 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011605 Uncertain Approved Cytosol Melanoma:3.06e-4 (unfavourable), Liver cancer:6.40e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 56.4 UNK KIAA1753, ZC3H5, ZC3HDC5 ENSG00000132478 Unkempt family zinc finger 17 75784771-75825799 Predicted intracellular proteins Evidence at protein level HPA023636, HPA027962 Uncertain Supported Cytosol
Cytoplasmic bodies Pancreatic cancer:6.58e-5 (favourable), Head and neck cancer:2.02e-4 (favourable) Expressed in all Expressed in all skin: 16.5 UPF1 HUPF1, KIAA0221, NORF1, pNORF1, RENT1, smg-2 ENSG00000005007 UPF1 regulator of nonsense transcripts homolog (yeast) 19 18831938-18868236 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA019587, HPA020857 Approved Supported Nucleoplasm Renal cancer:2.97e-6 (favourable), Melanoma:2.72e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 55.7 UPF2 DKFZP434D222, KIAA1408, RENT2, smg-3 ENSG00000151461 UPF2 regulator of nonsense transcripts homolog (yeast) 10 11920022-12043170 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA067008 Supported Cytosol
Cytoplasmic bodies Liver cancer:6.13e-4 (unfavourable) Expressed in all Expressed in all testis: 35.9 UPF3A HUPF3A, RENT3A, UPF3 ENSG00000169062 UPF3 regulator of nonsense transcripts homolog A (yeast) 13 114281584-114305817 Predicted intracellular proteins Evidence at protein level HPA018325, HPA061316 Approved Approved Nucleus
Vesicles
Cytosol Pancreatic cancer:7.09e-5 (favourable), Urothelial cancer:3.71e-4 (favourable) Expressed in all Expressed in all testis: 84.3 UPF3B HUPF3B, MRX62, RENT3B, UPF3X ENSG00000125351 UPF3 regulator of nonsense transcripts homolog B (yeast) X 119834022-119852998 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA001592, HPA001800, HPA001882 Approved Validated Nucleus
Nucleoli
Cytosol Renal cancer:1.44e-7 (unfavourable), Liver cancer:1.52e-6 (unfavourable), Melanoma:5.39e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex,endometrium: 18.4 UPK3BL UPLP ENSG00000267368 Uroplakin 3B-like 7 102637025-102642791 Predicted membrane proteins Evidence at protein level HPA011403 Supported Mixed Expressed in all esophagus: 139.3 UPRT DKFZp781E1243, FUR1, MGC23937, RP11-311P8.3 ENSG00000094841 Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) X 75274085-75304600 Predicted intracellular proteins Evidence at protein level HPA000805 Uncertain Approved Vesicles Renal cancer:4.14e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.1 UQCC1 BFZB, C20orf44, CBP3, FLJ10850, UQCC ENSG00000101019 Ubiquinol-cytochrome c reductase complex assembly factor 1 20 35302566-35412141 Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA034875 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments Expressed in all Expressed in all parathyroid gland: 42.6 UQCC2 bA6B20.2, C6orf125, Cbp6, M19, MGC14833, MNF1 ENSG00000137288 Ubiquinol-cytochrome c reductase complex assembly factor 2 6 33694293-33711727 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA039111 Uncertain Supported Nuclear bodies
Mitochondria Expressed in all Expressed in all testis: 130.8 UQCC3 C11orf83, UNQ655 ENSG00000204922 Ubiquinol-cytochrome c reductase complex assembly factor 3 11 62670273-62673687 Disease related genes, Predicted membrane proteins Evidence at protein level HPA046851 Approved Approved Nucleoplasm
Mitochondria
Cytosol Liver cancer:2.55e-4 (unfavourable) Expressed in all Expressed in all duodenum,small intestine: 8.2 UQCR10 HSPC051, QCR9, UCCR7.2, UCRC ENSG00000184076 Ubiquinol-cytochrome c reductase, complex III subunit X 22 29767369-29770413 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:5.45e-5 (favourable) Expressed in all Expressed in all heart muscle: 187.7 UQCR11 QCR10, UQCR ENSG00000127540 Ubiquinol-cytochrome c reductase, complex III subunit XI 19 1597172-1605490 Predicted membrane proteins Evidence at protein level Endometrial cancer:1.23e-4 (favourable), Renal cancer:1.65e-4 (favourable), Pancreatic cancer:1.86e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 111.9 UQCRB QCR7, QP-C, UQBP, UQCR6 ENSG00000156467 Ubiquinol-cytochrome c reductase binding protein 8 96225920-96235634 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA043060 Approved Renal cancer:2.90e-4 (favourable) Expressed in all Expressed in all heart muscle: 506.1 UQCRC1 D3S3191, QCR1, UQCR1 ENSG00000010256 Ubiquinol-cytochrome c reductase core protein I 3 48599002-48610976 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002815, HPA003525, CAB033782 Supported Supported Mitochondria
Cytosol Renal cancer:2.35e-10 (favourable) Expressed in all Expressed in all skeletal muscle: 88.3 UQCRC2 QCR2, UQCR2 ENSG00000140740 Ubiquinol-cytochrome c reductase core protein II 16 21952660-21983660 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA007998, HPA019146 Supported Validated Mitochondria Renal cancer:6.58e-9 (favourable) Expressed in all Expressed in all heart muscle: 296.6 UQCRFS1 RIP1, RIS1, RISP, UQCR5 ENSG00000169021 Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 19 29205321-29213541 Enzymes, Predicted intracellular proteins Evidence at protein level HPA041863, HPA050339 Supported Validated Mitochondria Renal cancer:3.92e-9 (favourable), Colorectal cancer:3.29e-4 (favourable), Ovarian cancer:3.84e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 70.9 UQCRH QCR6, UQCR8 ENSG00000173660 Ubiquinol-cytochrome c reductase hinge protein 1 46303631-46316776 Predicted intracellular proteins Evidence at protein level HPA042574 Supported Liver cancer:4.63e-5 (unfavourable) Expressed in all Expressed in all heart muscle: 459.5 UQCRQ QCR8, QP-C, UQCR7 ENSG00000164405 Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 5 132866560-132868031 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA046693, HPA053323 Approved Validated Mitochondria Endometrial cancer:4.23e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 376.1 URGCP DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4 ENSG00000106608 Upregulator of cell proliferation 7 43875894-43926411 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019879, HPA020134, HPA029468 Approved Supported Cytosol Renal cancer:1.90e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 33.8 URI1 C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI ENSG00000105176 URI1, prefoldin-like chaperone 19 29923644-30016608 Predicted intracellular proteins Evidence at protein level HPA071709 Approved Supported Nucleoplasm
Cytosol Endometrial cancer:1.12e-4 (unfavourable) Expressed in all Expressed in all testis: 94.6 URM1 C9orf74, MGC2668 ENSG00000167118 Ubiquitin related modifier 1 9 128371319-128392016 Predicted intracellular proteins Evidence at protein level HPA053645, HPA065160 Approved Approved Nucleoplasm
Vesicles Renal cancer:7.43e-6 (favourable), Liver cancer:6.91e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 24.9 UROD ENSG00000126088 Uroporphyrinogen decarboxylase 1 45012147-45015575 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA027468, HPA028668, HPA030350 Uncertain Supported Nucleoplasm
Cytosol Liver cancer:2.48e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 113.1 UROS ENSG00000188690 Uroporphyrinogen III synthase 10 125784980-125823248 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA044038 Approved Approved Nucleoplasm
Cytosol Renal cancer:6.27e-4 (unfavourable) Expressed in all Expressed in all epididymis: 88.6 USB1 C16orf57, FLJ13154, HVSL1, Mpn1 ENSG00000103005 U6 snRNA biogenesis 1 16 57999546-58021618 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA041791, HPA059854 Approved Supported Nucleus Liver cancer:6.69e-7 (unfavourable), Renal cancer:2.02e-4 (unfavourable) Expressed in all Expressed in all appendix: 38.5 USE1 D12, MDS032, p31, SLT1 ENSG00000053501 Unconventional SNARE in the ER 1 homolog (S. cerevisiae) 19 17215346-17219829 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026851, HPA047562 Approved Renal cancer:3.59e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 42.1 USF1 bHLHb11, MLTFI, UEF ENSG00000158773 Upstream transcription factor 1 1 161039251-161045977 Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB001480, HPA036233, HPA036535 Supported Validated Nucleoplasm Renal cancer:6.01e-12 (unfavourable), Urothelial cancer:1.95e-5 (favourable), Head and neck cancer:8.70e-4 (favourable) Expressed in all Expressed in all spleen: 35.5 USF2 bHLHb12, FIP ENSG00000105698 Upstream transcription factor 2, c-fos interacting 19 35268978-35279821 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029764, HPA046567 Supported Nucleoplasm
Vesicles Pancreatic cancer:5.12e-5 (favourable), Urothelial cancer:3.28e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 216.0 USMG5 bA792D24.4, DAPIT, MGC14697 ENSG00000173915 Up-regulated during skeletal muscle growth 5 homolog (mouse) 10 103389041-103396466 Predicted membrane proteins Evidence at protein level HPA044798 Supported Mitochondria Expressed in all Expressed in all heart muscle: 547.4 USO1 p115, TAP, VDP ENSG00000138768 USO1 vesicle transport factor 4 75724593-75814286 Predicted intracellular proteins Evidence at protein level CAB010108, HPA038282, HPA038283 Supported Validated Nucleoli fibrillar center
Golgi apparatus Expressed in all Expressed in all thyroid gland: 90.8 USP1 ENSG00000162607 Ubiquitin specific peptidase 1 1 62436297-62451804 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028387, HPA028440 Approved Supported Nucleoplasm Liver cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all testis: 91.8 USP10 KIAA0190, UBPO ENSG00000103194 Ubiquitin specific peptidase 10 16 84699978-84779922 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006731, HPA006749 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.00e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 61.9 USP11 UHX1 ENSG00000102226 Ubiquitin specific peptidase 11 X 47232690-47248328 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003103, HPA037536 Supported Approved Supported Nucleoplasm Renal cancer:4.13e-5 (favourable), Endometrial cancer:2.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 213.4 USP12 USP12L1 ENSG00000152484 Ubiquitin specific peptidase 12 13 27066142-27171896 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007288 Uncertain Expressed in all Expressed in all bone marrow: 45.8 USP13 IsoT-3 ENSG00000058056 Ubiquitin specific peptidase 13 (isopeptidase T-3) 3 179652755-179789401 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004827 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.46e-6 (unfavourable), Liver cancer:2.40e-5 (unfavourable), Urothelial cancer:3.06e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 52.2 USP14 TGT ENSG00000101557 Ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 18 158383-214629 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001308 Approved Supported Cytosol Liver cancer:4.30e-5 (unfavourable), Head and neck cancer:7.81e-5 (unfavourable), Ovarian cancer:7.91e-4 (favourable) Expressed in all Expressed in all prostate: 49.2 USP15 KIAA0529, UNPH4 ENSG00000135655 Ubiquitin specific peptidase 15 12 62260338-62417431 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006237, HPA006428, HPA071014 Approved Validated Cytosol Renal cancer:1.58e-5 (unfavourable), Liver cancer:8.04e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 121.9 USP16 Ubp-M ENSG00000156256 Ubiquitin specific peptidase 16 21 29024629-29054488 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021140 Supported Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 56.2 USP19 KIAA0891, ZMYND9 ENSG00000172046 Ubiquitin specific peptidase 19 3 49108046-49120938 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level Renal cancer:7.05e-9 (favourable) Expressed in all Expressed in all parathyroid gland: 45.0 USP20 KIAA1003 ENSG00000136878 Ubiquitin specific peptidase 20 9 129834698-129881838 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006287, HPA007008 Uncertain Approved Approved Nucleus
Plasma membrane
Cytosol Pancreatic cancer:1.54e-7 (favourable), Renal cancer:5.65e-5 (favourable), Colorectal cancer:2.48e-4 (unfavourable), Endometrial cancer:4.01e-4 (favourable), Cervical cancer:8.01e-4 (favourable) Expressed in all Expressed in all thyroid gland: 22.1 USP21 USP16, USP23 ENSG00000143258 Ubiquitin specific peptidase 21 1 161159450-161165723 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028397 Uncertain Supported Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:9.50e-6 (unfavourable), Urothelial cancer:3.35e-5 (favourable), Liver cancer:1.68e-4 (unfavourable), Endometrial cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 45.2 USP22 KIAA1063, USP3L ENSG00000124422 Ubiquitin specific peptidase 22 17 20999593-21043760 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044980 Supported Supported Nuclear speckles Renal cancer:1.53e-7 (favourable), Liver cancer:9.66e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 154.5 USP24 KIAA1057 ENSG00000162402 Ubiquitin specific peptidase 24 1 55066359-55215113 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026723, HPA028428, HPA067124 Approved Supported Nucleoplasm
Cytosol Liver cancer:1.34e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.4 USP25 USP21 ENSG00000155313 Ubiquitin specific peptidase 25 21 15730025-15880069 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018297, HPA024142 Approved Supported Cytosol Expressed in all Expressed in all testis: 97.1 USP28 KIAA1515 ENSG00000048028 Ubiquitin specific peptidase 28 11 113797874-113875570 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006778, HPA006779 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all heart muscle: 39.8 USP3 ENSG00000140455 Ubiquitin specific peptidase 3 15 63504511-63594640 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053275, HPA060513 Supported Nucleus Urothelial cancer:1.38e-4 (favourable) Expressed in all Expressed in all bone marrow: 32.1 USP30 FLJ40511, MGC10702 ENSG00000135093 Ubiquitin specific peptidase 30 12 109023089-109088026 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016952 Approved Renal cancer:5.23e-6 (favourable) Expressed in all Expressed in all testis: 25.5 USP32 NY-REN-60, USP10 ENSG00000170832 Ubiquitin specific peptidase 32 17 60179094-60422470 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044365 Approved Approved Golgi apparatus
Cytosol Endometrial cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all testis: 154.7 USP33 KIAA1097, VDU1 ENSG00000077254 Ubiquitin specific peptidase 33 1 77695987-77759852 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005719 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 55.0 USP34 KIAA0570, KIAA0729 ENSG00000115464 Ubiquitin specific peptidase 34 2 61187463-61470769 Enzymes, Predicted intracellular proteins Evidence at protein level HPA025815, HPA070764 Uncertain Approved Nucleus Expressed in all Expressed in all testis: 61.1 USP36 FLJ12851, KIAA1453 ENSG00000055483 Ubiquitin specific peptidase 36 17 78787381-78841441 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012082, HPA012395, HPA052860 Uncertain Approved Validated Nucleoli
Nuclear speckles Endometrial cancer:5.18e-5 (unfavourable) Expressed in all Expressed in all skin: 38.4 USP38 HP43.8KD, KIAA1891 ENSG00000170185 Ubiquitin specific peptidase 38 4 143184917-143223830 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036990, HPA047948 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.20e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 13.8 USP39 CGI-21, SAD1, SNRNP65 ENSG00000168883 Ubiquitin specific peptidase 39 2 85602856-85649282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034823 Approved Supported Nucleoplasm Renal cancer:4.05e-7 (unfavourable), Liver cancer:2.84e-6 (unfavourable), Endometrial cancer:5.52e-4 (unfavourable) Expressed in all Expressed in all placenta: 38.1 USP4 UNP, Unph ENSG00000114316 Ubiquitin specific peptidase 4 (proto-oncogene) 3 49277831-49340712 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018499 Approved Supported Plasma membrane
Cytosol Renal cancer:4.29e-5 (favourable), Lung cancer:4.46e-5 (favourable) Expressed in all Expressed in all testis: 56.7 USP40 FLJ10785 ENSG00000085982 Ubiquitin specific peptidase 40 2 233475520-233566782 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005821 Uncertain Approved Vesicles Expressed in all Expressed in all parathyroid gland: 30.9 USP46 FLJ12552 ENSG00000109189 Ubiquitin specific peptidase 46 4 52590972-52659335 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007288, CAB076369, CAB076370 Uncertain Validated Nucleoli Expressed in all Expressed in all cerebral cortex: 44.8 USP47 ENSG00000170242 Ubiquitin specific peptidase 47 11 11841423-11959323 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029286, HPA029289 Supported Approved Intermediate filaments Expressed in all Expressed in all parathyroid gland: 75.5 USP48 FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31 ENSG00000090686 Ubiquitin specific peptidase 48 1 21678298-21783606 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030045, HPA030046 Approved Approved Supported Nucleoplasm
Mitochondria
Cytosol Liver cancer:6.09e-8 (unfavourable) Expressed in all Expressed in all adrenal gland: 54.3 USP5 IsoT ENSG00000111667 Ubiquitin specific peptidase 5 (isopeptidase T) 12 6852128-6866632 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006756 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 87.6 USP7 HAUSP ENSG00000187555 Ubiquitin specific peptidase 7 (herpes virus-associated) 16 8892094-8964514 Enzymes, Predicted intracellular proteins Evidence at protein level CAB008108, HPA015641 Approved Renal cancer:8.56e-5 (favourable) Expressed in all Expressed in all testis: 108.6 USP8 HumORF8, KIAA0055, SPG59, UBPY ENSG00000138592 Ubiquitin specific peptidase 8 15 50424380-50514419 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004869, HPA050215 Uncertain Supported Golgi apparatus
Cytosol Renal cancer:1.29e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 75.8 USP9X DFFRX, FAF, MRX99 ENSG00000124486 Ubiquitin specific peptidase 9, X-linked X 41085635-41236579 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011618, HPA047417, CAB070164 Approved Uncertain Vesicles Expressed in all Expressed in all parathyroid gland: 88.6 USPL1 bA121O19.1, C13orf22, D13S106E ENSG00000132952 Ubiquitin specific peptidase like 1 13 30617693-30660770 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039342, HPA040172 Uncertain Expressed in all Expressed in all testis: 40.3 UTP11L CGI-94 ENSG00000183520 UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1 38009258-38024824 Predicted intracellular proteins Evidence at protein level HPA045830 Approved Approved Nucleus Renal cancer:1.42e-8 (unfavourable), Liver cancer:7.44e-8 (unfavourable) Expressed in all Expressed in all skeletal muscle: 37.3 UTP14A NY-CO-16, SDCCAG16 ENSG00000156697 UTP14A small subunit (SSU) processome component X 129906121-129929761 Predicted intracellular proteins Evidence at protein level HPA047217, HPA054023 Uncertain Supported Nucleoli
Cytosol Renal cancer:8.12e-8 (unfavourable), Head and neck cancer:7.67e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.4 UTP14C 2700066J21Rik, KIAA0266 ENSG00000253797 UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) 13 52024691-52033600 Predicted intracellular proteins Evidence at protein level HPA047217, HPA054023 Uncertain Approved Nucleoli
Cytosol Renal cancer:1.46e-5 (favourable), Ovarian cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 25.5 UTP15 FLJ12787, FLJ23637, NET21 ENSG00000164338 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) 5 73565443-73583377 Predicted intracellular proteins Evidence at protein level HPA044697 Supported Nucleoli
Endoplasmic reticulum Expressed in all Expressed in all bone marrow: 23.2 UTP18 CGI-48, WDR50 ENSG00000011260 UTP18 small subunit (SSU) processome component 17 51260528-51297936 Predicted intracellular proteins Evidence at protein level HPA052378 Approved Supported Nucleus
Nuclear membrane
Nucleoli Liver cancer:1.99e-4 (unfavourable), Colorectal cancer:3.33e-4 (favourable) Expressed in all Expressed in all testis: 105.6 UTP23 C8orf53, MGC14595 ENSG00000147679 UTP23, small subunit (SSU) processome component, homolog (yeast) 8 116766503-116849463 Predicted intracellular proteins Evidence at protein level HPA044418 Uncertain Approved Nucleoli Breast cancer:5.18e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 21.3 UTP3 CRLZ1, DKFZp761F222, FLJ23256, SAS10 ENSG00000132467 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 4 70688479-70690551 Predicted intracellular proteins Evidence at protein level HPA035655, HPA041453 Approved Approved Nucleoli Renal cancer:3.16e-4 (favourable) Expressed in all Expressed in all spleen: 43.9 UTP6 C17orf40, HCA66 ENSG00000108651 UTP6, small subunit (SSU) processome component, homolog (yeast) 17 31860899-31901765 Predicted intracellular proteins Evidence at protein level HPA025936, HPA055806 Supported Validated Nucleoli Renal cancer:1.16e-6 (unfavourable), Liver cancer:1.86e-5 (unfavourable) Expressed in all Expressed in all epididymis: 15.3 UTRN DMDL, DRP, DRP1 ENSG00000152818 Utrophin 6 144285701-144853034 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB016348, HPA018894 Supported Approved Nucleoplasm
Plasma membrane Renal cancer:7.61e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 171.0 UVRAG VPS38 ENSG00000198382 UV radiation resistance associated 11 75815167-76143195 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA016932 Uncertain Expressed in all Expressed in all parathyroid gland: 42.0 UXS1 FLJ23591, SDR6E1, UGD ENSG00000115652 UDP-glucuronate decarboxylase 1 2 106093303-106194339 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008825 Uncertain Liver cancer:1.38e-4 (unfavourable), Head and neck cancer:5.45e-4 (unfavourable), Ovarian cancer:7.94e-4 (favourable) Expressed in all Expressed in all placenta: 75.5 UXT ART-27, STAP1 ENSG00000126756 Ubiquitously-expressed, prefoldin-like chaperone X 47651798-47659161 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050499, HPA058400 Approved Supported Nucleus
Microtubule organizing center
Cytosol Expressed in all Expressed in all ovary: 183.7 VAC14 ArPIKfyve, FLJ10305, TAX1BP2 ENSG00000103043 Vac14 homolog (S. cerevisiae) 16 70687439-70801161 Predicted intracellular proteins Evidence at protein level HPA027766 Approved Approved Vesicles
Cytosol Renal cancer:1.56e-6 (favourable), Cervical cancer:8.33e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 31.0 VAMP2 SYB2, VAMP-2 ENSG00000220205 Vesicle-associated membrane protein 2 (synaptobrevin 2) 17 8159149-8163546 FDA approved drug targets, Predicted membrane proteins, Transporters Evidence at protein level CAB078785 Supported Renal cancer:9.76e-8 (favourable), Pancreatic cancer:3.83e-6 (favourable), Endometrial cancer:1.08e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 485.0 VAMP3 CEB ENSG00000049245 Vesicle-associated membrane protein 3 1 7771269-7781432 Cancer-related genes, Predicted membrane proteins Evidence at protein level Renal cancer:2.36e-4 (favourable) Expressed in all Expressed in all lung: 135.4 VAMP4 ENSG00000117533 Vesicle-associated membrane protein 4 1 171700160-171742247 Predicted membrane proteins Evidence at protein level HPA050418 Supported Approved Golgi apparatus Renal cancer:5.43e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 22.4 VAMP5 ENSG00000168899 Vesicle-associated membrane protein 5 2 85584408-85593412 Predicted membrane proteins Evidence at protein level HPA035082 Supported Approved Nucleoplasm
Plasma membrane Renal cancer:1.28e-5 (unfavourable) Expressed in all Expressed in all lung: 120.0 VAMP7 SYBL1, TI-VAMP, VAMP-7 ENSG00000124333 Vesicle-associated membrane protein 7 X 155881293-155943769 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036733 Approved Supported Vesicles Renal cancer:2.83e-4 (favourable) Expressed in all Expressed in all placenta: 56.8 VAMP8 EDB ENSG00000118640 Vesicle-associated membrane protein 8 2 85561562-85582031 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA006882, CAB037132, CAB037147 Supported Thyroid cancer:8.07e-9 (favourable), Urothelial cancer:1.59e-6 (favourable) Expressed in all Expressed in all lung: 328.4 VAPA hVAP-33, VAP-A ENSG00000101558 VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 18 9914002-9960021 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA009174 Approved Validated Endoplasmic reticulum Renal cancer:5.72e-7 (favourable) Expressed in all Expressed in all adrenal gland: 61.6 VAPB ALS8, VAP-B, VAP-C ENSG00000124164 VAMP (vesicle-associated membrane protein)-associated protein B and C 20 58389122-58451101 Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA013144, CAB013722 Supported Validated Endoplasmic reticulum Renal cancer:1.08e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 42.5 VASH1 KIAA1036 ENSG00000071246 Vasohibin 1 14 76762189-76783015 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000653 Uncertain Pancreatic cancer:6.56e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 34.5 VASP ENSG00000125753 Vasodilator-stimulated phosphoprotein 19 45506579-45526983 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004612, HPA005724 Supported Supported Plasma membrane
Cell Junctions
Focal adhesion sites Renal cancer:5.91e-7 (unfavourable), Liver cancer:3.49e-5 (unfavourable) Expressed in all Expressed in all appendix: 93.1 VAT1 FLJ20230, VATI ENSG00000108828 Vesicle amine transport 1 17 43014605-43025123 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045170 Uncertain Liver cancer:1.39e-4 (unfavourable), Renal cancer:5.89e-4 (favourable) Expressed in all Expressed in all adrenal gland: 243.0 VBP1 PFD3, PFDN3 ENSG00000155959 Von Hippel-Lindau binding protein 1 X 155197007-155239817 Predicted intracellular proteins Evidence at protein level CAB006260, HPA023230 Approved Supported Vesicles
Cytosol Expressed in all Expressed in all cerebral cortex: 85.5 VCL ENSG00000035403 Vinculin 10 73995193-74121363 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002131, CAB002453, HPA063777 Supported Validated Focal adhesion sites Pancreatic cancer:2.75e-4 (unfavourable) Expressed in all Expressed in all smooth muscle: 339.0 VCP IBMPFD, p97 ENSG00000165280 Valosin containing protein 9 35056064-35073249 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters Evidence at protein level CAB005593, HPA012728, HPA012814 Supported Validated Nucleoplasm
Cytosol Renal cancer:9.63e-7 (favourable), Endometrial cancer:7.30e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 92.6 VDAC1 MGC111064, PORIN ENSG00000213585 Voltage-dependent anion channel 1 5 133971915-134005133 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005885, HPA030780 Supported Approved Cytosol Lung cancer:2.87e-5 (unfavourable), Head and neck cancer:4.90e-4 (unfavourable), Breast cancer:5.30e-4 (unfavourable), Liver cancer:8.49e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 363.8 VDAC2 ENSG00000165637 Voltage-dependent anion channel 2 10 75210154-75231448 Predicted intracellular proteins, Transporters Evidence at protein level HPA043475 Supported Validated Mitochondria Head and neck cancer:4.51e-4 (unfavourable), Liver cancer:4.55e-4 (unfavourable) Expressed in all Expressed in all esophagus: 266.4 VDAC3 HD-VDAC3 ENSG00000078668 Voltage-dependent anion channel 3 8 42391624-42405897 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA026864 Uncertain Supported Mitochondria Expressed in all Expressed in all skeletal muscle: 327.2 VEGFA VEGF, VEGF-A, VPF ENSG00000112715 Vascular endothelial growth factor A 6 43770184-43786487 Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level CAB005429, CAB039240, HPA069116 Approved Renal cancer:1.76e-5 (unfavourable), Liver cancer:2.34e-5 (unfavourable), Endometrial cancer:2.10e-4 (unfavourable), Urothelial cancer:2.73e-4 (favourable), Cervical cancer:4.50e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 455.6 VEGFB VEGFL, VRF ENSG00000173511 Vascular endothelial growth factor B 11 64234538-64238793 Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins Evidence at protein level Expressed in all Expressed in all adipose tissue: 194.9 VEZF1 DB1, ZNF161 ENSG00000136451 Vascular endothelial zinc finger 1 17 57971547-57988259 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027520, HPA048315 Uncertain Validated Nucleoplasm Colorectal cancer:6.14e-5 (favourable), Liver cancer:6.46e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 81.7 VEZT DKFZP761C241 ENSG00000028203 Vezatin, adherens junctions transmembrane protein 12 95217746-95302790 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA004811, HPA017066 Approved Supported Nucleoplasm
Cytosol Renal cancer:1.93e-5 (unfavourable), Liver cancer:1.71e-4 (unfavourable), Stomach cancer:3.68e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 31.2 VGLL4 KIAA0121 ENSG00000144560 Vestigial-like family member 4 3 11556070-11771350 Predicted intracellular proteins Evidence at protein level HPA038225, HPA038614 Approved Approved Nucleus
Nucleoli fibrillar center Renal cancer:1.32e-5 (favourable) Expressed in all Expressed in all ovary: 110.5 VHL VHL1 ENSG00000134086 Von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 3 10141008-10152220 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB005430, HPA031631, HPA031632 Uncertain Validated Nucleoplasm
Cytosol Liver cancer:1.32e-5 (unfavourable), Breast cancer:9.02e-5 (unfavourable), Stomach cancer:7.84e-4 (favourable) Expressed in all Expressed in all lymph node: 35.2 VIM ENSG00000026025 Vimentin 10 17228259-17237593 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000080, HPA001762, CAB058687 Supported Supported Intermediate filaments Renal cancer:8.69e-8 (unfavourable), Endometrial cancer:9.75e-6 (favourable) Expressed in all Expressed in all ovary: 4341.9 VIMP AD-015, MGC2553, SBBI8, SELS, SEPS1 ENSG00000131871 VCP-interacting membrane selenoprotein 15 101270817-101277500 Predicted membrane proteins Evidence at protein level HPA010025 Approved Validated Endoplasmic reticulum Endometrial cancer:1.33e-4 (favourable), Ovarian cancer:5.19e-4 (favourable) Expressed in all Expressed in all testis: 141.3 VIPAS39 C14orf133, hSPE-39, SPE-39, SPE39, VIPAR, VPS16B ENSG00000151445 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 14 77426675-77457952 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003589, HPA003593 Approved Liver cancer:1.06e-6 (unfavourable) Expressed in all Expressed in all testis: 29.1 VKORC1 VKCFD2 ENSG00000167397 Vitamin K epoxide reductase complex, subunit 1 16 31090842-31095980 Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA042720 Approved Renal cancer:2.09e-10 (unfavourable) Expressed in all Expressed in all liver: 141.1 VKORC1L1 ENSG00000196715 Vitamin K epoxide reductase complex, subunit 1-like 1 7 65873267-65959563 Enzymes, FDA approved drug targets, Predicted membrane proteins Evidence at protein level HPA053954 Approved Supported Endoplasmic reticulum Expressed in all Expressed in all adipose tissue: 57.3 VMA21 MEAX, XMEA ENSG00000160131 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) X 151396515-151409364 Disease related genes, Predicted membrane proteins Evidence at protein level HPA010972 Uncertain Cervical cancer:2.30e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 30.1 VMP1 EPG3, TANGO5, TMEM49 ENSG00000062716 Vacuole membrane protein 1 17 59707192-59842255 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA030773, HPA064780 Uncertain Approved Nucleoli
Endoplasmic reticulum Renal cancer:2.77e-8 (unfavourable), Endometrial cancer:1.56e-5 (unfavourable), Liver cancer:8.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 64.7 VOPP1 DKFZp564K0822, ECop, FLJ20532, GASP ENSG00000154978 Vesicular, overexpressed in cancer, prosurvival protein 1 7 55436056-55572988 Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins Evidence at transcript level Renal cancer:6.99e-8 (unfavourable), Liver cancer:4.35e-5 (unfavourable) Expressed in all Expressed in all lymph node: 111.8 VPRBP DCAF1, KIAA0800, MGC102804 ENSG00000145041 Vpr (HIV-1) binding protein 3 51395867-51500002 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036142, HPA052445, HPA053203 Supported Validated Nucleus
Nucleoli fibrillar center Renal cancer:7.45e-5 (favourable) Expressed in all Expressed in all testis: 96.6 VPS11 PEP5, RNF108 ENSG00000160695 Vacuolar protein sorting 11 homolog (S. cerevisiae) 11 119067692-119081978 Predicted intracellular proteins Evidence at protein level HPA039020 Approved Approved Cytosol Renal cancer:1.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 26.0 VPS13A CHAC, KIAA0986 ENSG00000197969 Vacuolar protein sorting 13 homolog A (S. cerevisiae) 9 77177353-77421541 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA021652, HPA021662 Supported Expressed in all Expressed in all skin: 40.3 VPS13C FLJ10381, FLJ20136, KIAA1421 ENSG00000129003 Vacuolar protein sorting 13 homolog C (S. cerevisiae) 15 61852389-62060473 Predicted intracellular proteins Evidence at protein level HPA043507 Uncertain Approved Microtubules Expressed in all Expressed in all parathyroid gland: 26.9 VPS13D FLJ10619, KIAA0453 ENSG00000048707 Vacuolar protein sorting 13 homolog D (S. cerevisiae) 1 12230067-12512047 Predicted intracellular proteins Evidence at protein level HPA027332, HPA051621 Uncertain Approved Nucleoplasm
Vesicles
Cytosol Renal cancer:7.42e-12 (favourable) Expressed in all Expressed in all parathyroid gland: 29.0 VPS16 ENSG00000215305 Vacuolar protein sorting 16 homolog (S. cerevisiae) 20 2840703-2866732 Predicted intracellular proteins Evidence at protein level HPA043229, HPA048661 Approved Pancreatic cancer:5.89e-5 (favourable), Renal cancer:8.02e-5 (unfavourable), Liver cancer:1.43e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 29.0 VPS18 KIAA1475, PEP3 ENSG00000104142 Vacuolar protein sorting 18 homolog (S. cerevisiae) 15 40894430-40903975 Predicted intracellular proteins Evidence at protein level HPA040701 Approved Renal cancer:1.61e-6 (favourable), Pancreatic cancer:8.69e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 15.9 VPS25 DERP9, EAP20, MGC10540 ENSG00000131475 Vacuolar protein sorting 25 homolog (S. cerevisiae) 17 42773436-42779599 Predicted intracellular proteins Evidence at protein level CAB004978, HPA052217, HPA057284 Uncertain Approved Centrosome Colorectal cancer:3.18e-4 (favourable) Expressed in all Expressed in all fallopian tube: 92.2 VPS26A Hbeta58, PEP8A, VPS26 ENSG00000122958 VPS26 retromer complex component A 10 69123512-69172861 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011602, HPA057498, CAB075733 Supported Validated Endosomes
Lysosomes Liver cancer:1.70e-6 (unfavourable), Pancreatic cancer:9.18e-6 (unfavourable), Head and neck cancer:1.72e-4 (unfavourable) Expressed in all Expressed in all testis: 86.5 VPS26B MGC10485, Pep8b ENSG00000151502 VPS26 retromer complex component B 11 134224645-134247792 Predicted intracellular proteins Evidence at protein level HPA038172 Uncertain Expressed in all Expressed in all cerebral cortex: 60.5 VPS28 ENSG00000160948 Vacuolar protein sorting 28 homolog (S. cerevisiae) 8 144423601-144428563 Predicted intracellular proteins Evidence at protein level HPA024688, HPA024745 Supported Endometrial cancer:9.93e-4 (favourable) Expressed in all Expressed in all fallopian tube: 234.2 VPS29 DC15, DC7, PEP11 ENSG00000111237 VPS29 retromer complex component 12 110491097-110502117 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039748 Uncertain Supported Vesicles
Cytosol Liver cancer:2.79e-5 (unfavourable), Ovarian cancer:7.70e-4 (favourable) Expressed in all Expressed in all epididymis: 107.2 VPS33B FLJ14848 ENSG00000184056 Vacuolar protein sorting 33 homolog B (yeast) 15 90998416-91022603 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040415 Approved Expressed in all Expressed in all cerebral cortex: 16.2 VPS36 C13orf9, CGI-145, Eap45 ENSG00000136100 Vacuolar protein sorting 36 homolog (S. cerevisiae) 13 52412602-52450628 Predicted intracellular proteins Evidence at protein level HPA039734, HPA043947 Approved Supported Vesicles
Lysosomes
Plasma membrane
Cell Junctions Renal cancer:9.91e-6 (favourable) Expressed in all Expressed in all skin: 62.6 VPS37A FLJ32642, HCRP1, PQBP2, SPG53 ENSG00000155975 Vacuolar protein sorting 37 homolog A (S. cerevisiae) 8 17246571-17302427 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA024705, HPA024781 Supported Approved Vesicles
Centrosome
Cytosol Expressed in all Expressed in all testis: 57.1 VPS37B FLJ12750 ENSG00000139722 Vacuolar protein sorting 37 homolog B (S. cerevisiae) 12 122865328-122896444 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA038217, HPA038218 Supported Renal cancer:1.35e-6 (favourable) Expressed in all Expressed in all esophagus: 34.9 VPS37C FLJ20847 ENSG00000167987 Vacuolar protein sorting 37 homolog C (S. cerevisiae) 11 61130256-61161617 Predicted intracellular proteins Evidence at protein level HPA043348 Approved Approved Nucleus
Vesicles Renal cancer:2.37e-7 (favourable), Liver cancer:5.85e-5 (unfavourable) Expressed in all Expressed in all skin: 25.2 VPS39 KIAA0770, VAM6 ENSG00000166887 Vacuolar protein sorting 39 homolog (S. cerevisiae) 15 42158701-42208316 Plasma proteins, Predicted intracellular proteins Evidence at protein level Endometrial cancer:3.21e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 64.4 VPS41 HVSP41 ENSG00000006715 Vacuolar protein sorting 41 homolog (S. cerevisiae) 7 38722963-38932394 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA020080, HPA020299 Approved Renal cancer:3.40e-8 (favourable) Expressed in all Expressed in all cerebral cortex: 97.0 VPS45 h-vps45, H1, VPS45A, VPS45B ENSG00000136631 Vacuolar protein sorting 45 homolog (S. cerevisiae) 1 150067293-150145327 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027425, HPA027441 Uncertain Approved Microtubules Liver cancer:6.57e-6 (unfavourable), Renal cancer:1.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 37.7 VPS4A FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1 ENSG00000132612 Vacuolar protein sorting 4 homolog A (S. cerevisiae) 16 69311356-69326939 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018751, CAB034411, HPA060092 Approved Supported Midbody Renal cancer:1.76e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 46.8 VPS4B SKD1, SKD1B, VPS4-2 ENSG00000119541 Vacuolar protein sorting 4 homolog B (S. cerevisiae) 18 63389190-63422483 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040393, CAB046445, HPA057649 Approved Approved Vesicles
Intermediate filaments Renal cancer:1.23e-4 (favourable) Expressed in all Expressed in all esophagus: 83.0 VPS50 CCDC132, DKFZp313I2429, FLJ20097, KIAA1861, VPS54L ENSG00000004766 VPS50 EARP/GARPII complex subunit 7 93232340-93361121 Predicted intracellular proteins Evidence at protein level HPA026679 Approved Uncertain Plasma membrane
Cytosol Renal cancer:1.35e-6 (favourable), Liver cancer:7.21e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 25.5 VPS51 ANG2, ANG3, C11orf2, C11orf3, FFR ENSG00000149823 Vacuolar protein sorting 51 homolog (S. cerevisiae) 11 65089324-65111860 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA039650, HPA061447 Uncertain Approved Nucleoli
Golgi apparatus
Vesicles Renal cancer:2.41e-9 (favourable) Expressed in all Expressed in all ovary: 102.0 VPS53 FLJ10979, HCCS1 ENSG00000141252 Vacuolar protein sorting 53 homolog (S. cerevisiae) 17 508668-721717 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA022988, HPA024446 Approved Approved Golgi apparatus
Cytosol Endometrial cancer:1.08e-5 (favourable), Pancreatic cancer:1.56e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 18.7 VPS54 HCC8, PPP1R164 ENSG00000143952 Vacuolar protein sorting 54 homolog (S. cerevisiae) 2 63892146-64019072 Predicted intracellular proteins Evidence at protein level HPA055894, HPA067981, HPA070582 Validated Nucleoplasm
Golgi apparatus Pancreatic cancer:2.03e-4 (favourable), Liver cancer:2.47e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 58.8 VPS72 Swc2, TCFL1, YL-1, YL1 ENSG00000163159 Vacuolar protein sorting 72 homolog (S. cerevisiae) 1 151169987-151195321 Predicted intracellular proteins Evidence at protein level HPA065709 Supported Nuclear speckles Liver cancer:4.41e-6 (unfavourable) Expressed in all Expressed in all cerebral cortex: 30.9 VPS8 FLJ32099, KIAA0804 ENSG00000156931 Vacuolar protein sorting 8 homolog (S. cerevisiae) 3 184812143-185052614 Predicted intracellular proteins Evidence at protein level HPA036871 Uncertain Approved Plasma membrane
Cytosol Expressed in all Expressed in all testis: 31.0 VPS9D1 ATP-BL, C16orf7 ENSG00000075399 VPS9 domain containing 1 16 89707134-89720986 Predicted intracellular proteins Evidence at protein level HPA007847, HPA023620 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:2.91e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 26.5 VRK2 ENSG00000028116 Vaccinia related kinase 2 2 57907651-58159920 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB046459, HPA047503 Approved Supported Endoplasmic reticulum Liver cancer:6.32e-6 (unfavourable), Renal cancer:4.66e-5 (unfavourable), Pancreatic cancer:4.65e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 29.2 VRK3 ENSG00000105053 Vaccinia related kinase 3 19 49976467-50025946 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA056489 Approved Supported Nucleus
Vesicles Renal cancer:1.83e-4 (favourable), Urothelial cancer:5.66e-4 (favourable) Expressed in all Expressed in all testis: 168.2 VSIG4 Z39IG ENSG00000155659 V-set and immunoglobulin domain containing 4 X 66021738-66040125 Plasma proteins, Predicted membrane proteins Evidence at protein level HPA003903, CAB026000 Approved Uncertain Nucleoli
Plasma membrane
Cytosol Renal cancer:1.95e-6 (unfavourable), Colorectal cancer:1.34e-4 (unfavourable) Expressed in all Expressed in all lung: 243.3 VTA1 C6orf55, HSPC228, My012 ENSG00000009844 Vesicle (multivesicular body) trafficking 1 6 142147162-142224689 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030968, HPA030969 Approved Supported Nucleoplasm
Vesicles
Cytosol Liver cancer:6.58e-6 (unfavourable), Breast cancer:7.02e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 61.1 VTI1B VTI2 ENSG00000100568 Vesicle transport through interaction with t-SNAREs 1B 14 67647075-67674831 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA044121, HPA048150, HPA060118 Approved Validated Golgi apparatus
Vesicles Renal cancer:3.53e-12 (favourable) Expressed in all Expressed in all epididymis: 62.3 VWA5A BCSC-1, LOH11CR2A ENSG00000110002 Von Willebrand factor A domain containing 5A 11 124115362-124147721 Predicted intracellular proteins Evidence at protein level HPA037813, HPA037814, HPA061500 Uncertain Validated Nucleus Renal cancer:1.55e-5 (favourable) Expressed in all Expressed in all gallbladder: 48.9 VWA8 KIAA0564 ENSG00000102763 Von Willebrand factor A domain containing 8 13 41566837-41961120 Predicted intracellular proteins Evidence at protein level HPA039075, HPA045478 Uncertain Approved Vesicles
Lipid droplets Renal cancer:6.38e-14 (favourable), Liver cancer:8.56e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 21.3 VWA9 C15orf44, DKFZP564O1664 ENSG00000138614 Von Willebrand factor A domain containing 9 15 65578753-65611289 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA040255, HPA040651 Approved Approved Nucleoplasm
Nuclear membrane
Nuclear bodies
Mitochondria Expressed in all Expressed in all fallopian tube: 38.7 WAC BM-016, FLJ31290, MGC10753, PRO1741, Wwp4 ENSG00000095787 WW domain containing adaptor with coiled-coil 10 28532493-28623112 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA036528, HPA042609 Approved Supported Nucleoplasm Liver cancer:9.27e-6 (unfavourable) Expressed in all Expressed in all parathyroid gland: 129.7 WAPL FOE, KIAA0261, WAPAL ENSG00000062650 WAPL cohesin release factor 10 86435256-86521815 Predicted intracellular proteins Evidence at protein level HPA037874, HPA037875 Supported Expressed in all Expressed in all testis: 64.2 WARS IFI53, IFP53 ENSG00000140105 Tryptophanyl-tRNA synthetase 14 100333788-100376805 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005573, HPA018944 Validated Cytosol Ovarian cancer:1.94e-4 (favourable), Liver cancer:7.88e-4 (unfavourable) Expressed in all Expressed in all placenta: 468.8 WARS2 TrpRS ENSG00000116874 Tryptophanyl tRNA synthetase 2, mitochondrial 1 119031216-119140671 Enzymes, Predicted intracellular proteins Evidence at protein level HPA069692 Supported Supported Plasma membrane
Mitochondria Renal cancer:1.45e-4 (favourable) Expressed in all Expressed in all fallopian tube: 15.2 WASF2 SCAR2, WAVE2 ENSG00000158195 WAS protein family, member 2 1 27404226-27490158 Predicted intracellular proteins Evidence at protein level CAB022632, HPA045288 Supported Approved Plasma membrane
Cytosol Liver cancer:5.29e-8 (unfavourable), Ovarian cancer:8.48e-4 (unfavourable) Expressed in all Expressed in all esophagus: 88.5 WASH1 FAM39E, FLJ00038 ENSG00000181404 WAS protein family homolog 1 9 14521-29739 Predicted intracellular proteins Evidence at protein level HPA002689 Uncertain Approved Vesicles Expressed in all Expressed in all epididymis: 23.6 WASL N-WASP, NWASP, WASPB ENSG00000106299 Wiskott-Aldrich syndrome-like 7 123681935-123749067 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005399, HPA005750 Supported Approved Nucleoli
Cytosol Renal cancer:4.51e-8 (favourable), Pancreatic cancer:5.30e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 72.6 WBP1 WBP-1 ENSG00000239779 WW domain binding protein 1 2 74458329-74460891 Predicted membrane proteins Evidence at protein level HPA057067 Approved Approved Cytosol Colorectal cancer:1.04e-4 (unfavourable), Urothelial cancer:6.36e-4 (favourable), Pancreatic cancer:6.83e-4 (favourable) Expressed in all Expressed in all thyroid gland: 91.2 WBP11 NPWBP, PPP1R165, SIPP1 ENSG00000084463 WW domain binding protein 11 12 14784579-14803540 Predicted intracellular proteins Evidence at protein level HPA039710, HPA040037, HPA046403, HPA049126 Approved Validated Nucleoplasm Liver cancer:9.40e-4 (unfavourable) Expressed in all Expressed in all testis: 68.8 WBP1L C10orf26, FLJ20154, OPAL1 ENSG00000166272 WW domain binding protein 1-like 10 102743970-102816267 Predicted membrane proteins Evidence at protein level HPA037635, HPA038371 Uncertain Approved Nucleoplasm
Microtubules Renal cancer:1.56e-6 (favourable), Endometrial cancer:4.03e-4 (favourable) Expressed in all Expressed in all thyroid gland: 69.6 WBP2 WBP-2 ENSG00000132471 WW domain binding protein 2 17 75845699-75856507 Predicted intracellular proteins Evidence at protein level HPA065682, HPA068819 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 361.8 WBP4 FBP21, MGC117310 ENSG00000120688 WW domain binding protein 4 13 41061274-41084006 Predicted intracellular proteins Evidence at protein level HPA038965, HPA058738 Approved Supported Nucleoplasm
Vesicles
Plasma membrane Thyroid cancer:2.89e-4 (favourable) Expressed in all Expressed in all endometrium: 27.5 WBP5 DKFZp313K1940, TCEAL9, WEX6 ENSG00000185222 WW domain binding protein 5 X 103356445-103358469 Predicted intracellular proteins Evidence at protein level HPA011790 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all placenta: 274.5 WBSCR16 ENSG00000274523 Williams-Beuren syndrome chromosome region 16 7 75027122-75074228 Predicted intracellular proteins Evidence at protein level HPA052184, HPA060643 Approved Approved Nucleus
Cytosol Glioma:6.65e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 36.4 WBSCR22 MERM1, MGC19709, MGC2022, MGC5140, PP3381, WBMT ENSG00000071462 Williams Beuren syndrome chromosome region 22 7 73683025-73705161 Predicted intracellular proteins Evidence at protein level HPA052185 Approved Supported Nucleus
Nucleoli Renal cancer:1.46e-4 (unfavourable), Liver cancer:9.92e-4 (unfavourable) Expressed in all Expressed in all testis: 207.5 WDFY1 FENS-1, KIAA1435, WDF1, ZFYVE17 ENSG00000085449 WD repeat and FYVE domain containing 1 2 223855716-223945387 Predicted intracellular proteins Evidence at protein level HPA050603 Approved Expressed in all Expressed in all placenta: 38.5 WDFY3 ALFY, KIAA0993, ZFYVE25 ENSG00000163625 WD repeat and FYVE domain containing 3 4 84669610-84966391 Predicted intracellular proteins Evidence at protein level HPA042734, HPA048572 Approved Approved Nucleoli
Plasma membrane
Cytosol Renal cancer:3.64e-5 (favourable), Stomach cancer:9.35e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.6 WDR1 ENSG00000071127 WD repeat domain 1 4 10074339-10116949 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB020804, HPA036434, HPA058132 Approved Validated Cytosol Renal cancer:1.73e-5 (favourable) Expressed in all Expressed in all smooth muscle: 305.5 WDR13 ENSG00000101940 WD repeat domain 13 X 48590042-48608867 Predicted intracellular proteins Evidence at protein level HPA000913 Supported Supported Nucleoplasm
Plasma membrane
Microtubule organizing center Expressed in all Expressed in all fallopian tube: 90.6 WDR18 Ipi3 ENSG00000065268 WD repeat domain 18 19 984271-998438 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA050193, HPA050200 Approved Approved Nucleoplasm Expressed in all Expressed in all cerebral cortex: 18.0 WDR20 DMR, FLJ33659, MGC33177 ENSG00000140153 WD repeat domain 20 14 102139503-102224847 Predicted intracellular proteins Evidence at protein level Renal cancer:3.26e-9 (favourable) Expressed in all Expressed in all testis: 41.2 WDR24 C16orf21, DKFZp434F054, JFP7 ENSG00000127580 WD repeat domain 24 16 684622-690444 Predicted intracellular proteins Evidence at protein level HPA039506 Approved Renal cancer:3.75e-6 (favourable) Expressed in all Expressed in all testis: 11.9 WDR25 C14orf67, MGC4645 ENSG00000176473 WD repeat domain 25 14 100376418-100530303 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003113 Approved Supported Nucleoplasm Renal cancer:3.89e-5 (favourable), Liver cancer:7.36e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 13.5 WDR26 FLJ21016, GID7 ENSG00000162923 WD repeat domain 26 1 224385143-224437033 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028539, HPA061094 Supported Validated Nucleoplasm
Cytosol Renal cancer:3.31e-6 (unfavourable) Expressed in all Expressed in all testis: 53.8 WDR3 DIP2, FLJ12796, UTP12 ENSG00000065183 WD repeat domain 3 1 117929720-117966542 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA027509, HPA054354 Approved Supported Nucleus
Nuclear membrane
Nucleoli Liver cancer:7.33e-5 (unfavourable), Pancreatic cancer:8.82e-4 (unfavourable) Expressed in all Expressed in all testis: 22.3 WDR33 FLJ11294, NET14, WDC146 ENSG00000136709 WD repeat domain 33 2 127701022-127811187 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA026897, HPA046527 Supported Supported Nucleoplasm
Nucleoli fibrillar center Liver cancer:2.13e-4 (unfavourable) Expressed in all Expressed in all testis: 38.5 WDR34 bA216B9.3, DIC5, FAP133, MGC20486 ENSG00000119333 WD repeat domain 34 9 128633661-128656787 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040764, HPA041091 Approved Approved Cytosol Endometrial cancer:7.01e-5 (favourable), Cervical cancer:1.63e-4 (favourable), Liver cancer:8.79e-4 (unfavourable) Expressed in all Expressed in all testis: 53.0 WDR36 GLC1G, TA-WDRP, UTP21 ENSG00000134987 WD repeat domain 36 5 111091716-111130502 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA037796, HPA037797 Supported Supported Nucleoli Thyroid cancer:1.18e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.1 WDR37 KIAA0982 ENSG00000047056 WD repeat domain 37 10 1049538-1132297 Predicted intracellular proteins Evidence at protein level HPA037376, HPA037565 Supported Uncertain Intermediate filaments
Centrosome
Cytosol Pancreatic cancer:1.46e-6 (favourable), Thyroid cancer:1.34e-5 (unfavourable), Head and neck cancer:1.75e-5 (favourable) Expressed in all Expressed in all testis: 36.5 WDR41 FLJ10904 ENSG00000164253 WD repeat domain 41 5 77425970-77620611 Predicted intracellular proteins Evidence at protein level HPA043124 Approved Approved Nucleus
Golgi apparatus
Cytosol Liver cancer:4.47e-4 (unfavourable) Expressed in all Expressed in all testis: 51.4 WDR43 KIAA0007, NET12, UTP5 ENSG00000163811 WD repeat domain 43 2 28894643-28948222 Predicted intracellular proteins Evidence at protein level HPA044733 Uncertain Liver cancer:3.66e-5 (unfavourable), Endometrial cancer:5.70e-4 (unfavourable) Expressed in all Expressed in all testis: 36.3 WDR44 DKFZp686L20145, RAB11BP, RPH11 ENSG00000131725 WD repeat domain 44 X 118346073-118449961 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA038084, HPA046719 Approved Supported Golgi apparatus Expressed in all Expressed in all parathyroid gland: 22.8 WDR45 JM5, NBIA5, WDRX1, WIPI4 ENSG00000196998 WD repeat domain 45 X 49071470-49101170 Disease related genes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA027562 Uncertain Approved Nucleoli Cervical cancer:1.21e-4 (favourable), Head and neck cancer:1.61e-4 (favourable) Expressed in all Expressed in all epididymis: 133.5 WDR45B WDR45L, WIPI3 ENSG00000141580 WD repeat domain 45B 17 82614562-82648553 Predicted intracellular proteins Evidence at protein level HPA017886 Approved Nucleus
Golgi apparatus
Cytosol Liver cancer:2.98e-5 (unfavourable) Expressed in all Expressed in all testis: 82.9 WDR47 KIAA0893 ENSG00000085433 WD repeat domain 47 1 108970214-109042113 Predicted intracellular proteins Evidence at protein level HPA027287, HPA027289 Approved Approved Actin filaments Head and neck cancer:9.86e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 73.5 WDR48 KIAA1449, P80, SPG60 ENSG00000114742 WD repeat domain 48 3 39051998-39096671 Predicted intracellular proteins Evidence at protein level HPA038421, HPA058015 Approved Supported Vesicles Renal cancer:1.63e-7 (favourable) Expressed in all Expressed in all testis: 72.3 WDR5 CFAP89, SWD3 ENSG00000196363 WD repeat domain 5 9 134135365-134159968 Predicted intracellular proteins Evidence at protein level HPA047182 Supported Nucleoplasm Expressed in all Expressed in all testis: 62.9 WDR55 FLJ20195, FLJ21702 ENSG00000120314 WD repeat domain 55 5 140664676-140674124 Predicted intracellular proteins Evidence at protein level HPA043470, HPA048143 Uncertain Approved Nucleus
Nucleoli Liver cancer:8.88e-6 (unfavourable), Breast cancer:1.51e-4 (unfavourable) Expressed in all Expressed in all appendix: 13.1 WDR59 FLJ12270 ENSG00000103091 WD repeat domain 59 16 74871367-75000173 Predicted intracellular proteins Evidence at protein level HPA041084, HPA048218 Approved Approved Cytosol Expressed in all Expressed in all parathyroid gland: 43.0 WDR6 ENSG00000178252 WD repeat domain 6 3 49007062-49015953 Predicted intracellular proteins Evidence at protein level HPA042622 Approved Supported Plasma membrane
Cytosol Liver cancer:2.97e-6 (unfavourable), Renal cancer:4.52e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 199.7 WDR60 FAP163, FLJ10300 ENSG00000126870 WD repeat domain 60 7 158856578-158956747 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA020607, HPA021316 Approved Approved Microtubule organizing center Expressed in all Expressed in all testis: 75.4 WDR61 REC14 ENSG00000140395 WD repeat domain 61 15 78277835-78299794 Predicted intracellular proteins Evidence at protein level HPA039932, HPA040065 Supported Validated Nucleoplasm
Cytosol Renal cancer:2.03e-10 (favourable) Expressed in all Expressed in all epididymis: 128.8 WDR70 FLJ10233 ENSG00000082068 WD repeat domain 70 5 37379212-37753435 Predicted intracellular proteins Evidence at protein level HPA043064, HPA048149 Uncertain Approved Mitochondria
Cytosol Melanoma:3.73e-4 (unfavourable), Endometrial cancer:4.34e-4 (unfavourable) Expressed in all Expressed in all endometrium: 18.3 WDR74 FLJ10439 ENSG00000133316 WD repeat domain 74 11 62832342-62841809 Predicted intracellular proteins Evidence at protein level HPA037795, HPA038419 Uncertain Supported Nucleus
Nucleoli Expressed in all Expressed in all bone marrow: 83.6 WDR75 FLJ12519, NET16, UTP17 ENSG00000115368 WD repeat domain 75 2 189441433-189475565 Predicted intracellular proteins Evidence at protein level HPA038199 Approved Approved Nucleoplasm Renal cancer:3.15e-11 (unfavourable), Liver cancer:6.50e-8 (unfavourable) Expressed in all Expressed in all endometrium: 39.3 WDR77 MEP50, p44 ENSG00000116455 WD repeat domain 77 1 111439890-111449376 Predicted intracellular proteins Evidence at protein level HPA026437, HPA026448, HPA027271 Approved Supported Nucleoplasm
Golgi apparatus
Cytosol Liver cancer:2.06e-6 (unfavourable), Ovarian cancer:7.88e-4 (favourable) Expressed in all Expressed in all fallopian tube: 161.0 WDR82 MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A ENSG00000164091 WD repeat domain 82 3 52254421-52288020 Predicted intracellular proteins Evidence at protein level HPA040427 Approved Nucleoli Expressed in all Expressed in all endometrium: 93.1 WDR83OS C19orf56, PTD008 ENSG00000105583 WD repeat domain 83 opposite strand 19 12668071-12671356 Predicted membrane proteins Evidence at protein level HPA065685 Approved Endoplasmic reticulum Lung cancer:2.09e-4 (favourable), Ovarian cancer:8.84e-4 (favourable) Expressed in all Expressed in all fallopian tube: 315.6 WDR89 C14orf150, MGC9907 ENSG00000140006 WD repeat domain 89 14 63597039-63641861 Predicted intracellular proteins Evidence at protein level HPA000813 Uncertain Approved Intermediate filaments
Cytosol Liver cancer:3.26e-4 (unfavourable), Breast cancer:3.37e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.6 WDSUB1 FLJ36175, UBOX6, WDSAM1 ENSG00000196151 WD repeat, sterile alpha motif and U-box domain containing 1 2 159235793-159286799 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036840, HPA058172 Uncertain Approved Nucleus
Nucleoli
Cytosol Liver cancer:2.67e-4 (unfavourable), Cervical cancer:3.35e-4 (favourable) Expressed in all Expressed in all thyroid gland: 27.9 WDTC1 ADP, DCAF9, KIAA1037 ENSG00000142784 WD and tetratricopeptide repeats 1 1 27234516-27308633 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028177, HPA028180, HPA028182 Uncertain Supported Golgi apparatus
Vesicles Renal cancer:8.84e-8 (favourable), Cervical cancer:4.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 72.3 WDYHV1 C8orf32, FLJ10204 ENSG00000156795 WDYHV motif containing 1 8 123416725-123467230 Predicted intracellular proteins Evidence at protein level HPA024823, HPA053680 Approved Supported Nucleoplasm
Vesicles Endometrial cancer:4.93e-5 (unfavourable), Liver cancer:3.47e-4 (unfavourable) Expressed in all Expressed in all testis: 18.4 WEE1 WEE1A ENSG00000166483 WEE1 G2 checkpoint kinase 11 9573681-9593457 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004619, HPA068845 Approved Approved Nucleoli Renal cancer:5.19e-4 (unfavourable) Expressed in all Expressed in all endometrium: 89.6 WHAMM KIAA1971, WHAMM1, WHDC1 ENSG00000156232 WAS protein homolog associated with actin, golgi membranes and microtubules 15 82809628-82836108 Predicted intracellular proteins Evidence at protein level HPA039690, HPA040231 Supported Supported Cytosol Prostate cancer:2.31e-4 (unfavourable), Cervical cancer:7.09e-4 (favourable) Expressed in all Expressed in all bone marrow: 19.0 WHSC1 MMSET, NSD2 ENSG00000109685 Wolf-Hirschhorn syndrome candidate 1 4 1871424-1982207 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015801, CAB068246, CAB068247 Supported Supported Nucleus Liver cancer:2.61e-4 (unfavourable), Renal cancer:7.19e-4 (unfavourable) Expressed in all Expressed in all testis: 66.9 WHSC1L1 FLJ20353, NSD3 ENSG00000147548 Wolf-Hirschhorn syndrome candidate 1-like 1 8 38269697-38382272 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA005659, CAB013721, HPA018893 Uncertain Approved Nucleoplasm
Mitochondria Pancreatic cancer:7.48e-4 (unfavourable) Expressed in all Expressed in all placenta: 47.5 WIPF1 WASPIP, WIP ENSG00000115935 WAS/WASL interacting protein family, member 1 2 174559572-174682916 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA003739, CAB009737, HPA070706 Supported Approved Plasma membrane
Cytosol Renal cancer:1.14e-4 (unfavourable) Expressed in all Expressed in all lymph node: 159.5 WIPF2 WICH, WIRE ENSG00000171475 WAS/WASL interacting protein family, member 2 17 40219304-40284136 Predicted intracellular proteins Evidence at protein level HPA024000, HPA024001, HPA024467 Supported Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 32.5 WIPI1 Atg18, ATG18A, FLJ10055, WIPI49 ENSG00000070540 WD repeat domain, phosphoinositide interacting 1 17 68420948-68457513 Predicted intracellular proteins Evidence at protein level HPA007493, CAB037230 Supported Melanoma:3.11e-4 (favourable) Expressed in all Expressed in all placenta: 89.4 WIPI2 ATG18B, Atg21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984 ENSG00000157954 WD repeat domain, phosphoinositide interacting 2 7 5190188-5233826 Predicted intracellular proteins Evidence at protein level HPA019852, HPA021488 Uncertain Supported Nucleoplasm
Cytosol Renal cancer:2.05e-6 (favourable), Endometrial cancer:7.69e-5 (unfavourable), Pancreatic cancer:9.78e-4 (favourable) Expressed in all Expressed in all testis: 92.4 WIZ ZNF803 ENSG00000011451 Widely interspaced zinc finger motifs 19 15419980-15449951 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA022923, HPA023774 Supported Validated Nucleoplasm
Midbody Endometrial cancer:5.12e-5 (unfavourable) Expressed in all Expressed in all testis: 31.0 WLS C1orf139, EVI, FLJ23091, GPR177, mig-14, MRP, wls ENSG00000116729 Wntless Wnt ligand secretion mediator 1 68098473-68233120 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA069520 Approved Supported Endoplasmic reticulum Renal cancer:3.67e-7 (favourable), Urothelial cancer:3.51e-4 (unfavourable), Breast cancer:4.03e-4 (favourable), Ovarian cancer:9.43e-4 (favourable) Expressed in all Expressed in all epididymis: 160.7 WNK1 HSAN2, HSN2, PPP1R167, PRKWNK1 ENSG00000060237 WNK lysine deficient protein kinase 1 12 752593-911452 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA046541, HPA059157 Supported Supported Cytosol Ovarian cancer:9.67e-4 (unfavourable) Expressed in all Expressed in all esophagus: 92.7 WRAP73 WDR8 ENSG00000116213 WD repeat containing, antisense to TP73 1 3630767-3652761 Predicted intracellular proteins Evidence at protein level HPA026893 Uncertain Approved Nucleoplasm
Cell Junctions Liver cancer:1.37e-4 (unfavourable), Renal cancer:1.42e-4 (unfavourable), Pancreatic cancer:3.49e-4 (favourable) Expressed in all Expressed in all lymph node: 20.7 WRB CHD5, GET1 ENSG00000182093 Tryptophan rich basic protein 21 39380244-39428528 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA018527 Approved Expressed in all Expressed in all fallopian tube: 107.8 WRNIP1 bA420G6.2, FLJ22526, WHIP ENSG00000124535 Werner helicase interacting protein 1 6 2765414-2786952 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA031752, HPA031753 Supported Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 77.3 WSB1 DKFZp564A122, DKFZp564B0482, SWIP1 ENSG00000109046 WD repeat and SOCS box containing 1 17 27294076-27315926 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003293 Approved Approved Mitochondria Renal cancer:1.02e-7 (unfavourable), Liver cancer:4.07e-5 (unfavourable) Expressed in all Expressed in all placenta: 106.3 WSB2 MGC10210, SBA2 ENSG00000176871 WD repeat and SOCS box containing 2 12 118032694-118062430 Predicted intracellular proteins Evidence at protein level HPA052606 Uncertain Liver cancer:2.42e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 193.8 WTAP KIAA0105, MGC3925, Mum2 ENSG00000146457 Wilms tumor 1 associated protein 6 159725585-159756319 Predicted intracellular proteins Evidence at protein level HPA010549, HPA010550 Supported Validated Nucleoplasm
Nuclear speckles Liver cancer:6.57e-6 (unfavourable), Renal cancer:3.01e-5 (unfavourable), Ovarian cancer:7.51e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 177.4 WWC3 BM042, KIAA1280 ENSG00000047644 WWC family member 3 X 10015562-10144478 Predicted intracellular proteins Evidence at protein level HPA039814 Uncertain Approved Actin filaments
Cytosol Renal cancer:1.06e-5 (unfavourable), Colorectal cancer:1.31e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 39.4 WWOX FOR, SDR41C1, WOX1 ENSG00000186153 WW domain containing oxidoreductase 16 78099413-79212667 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA050992 Approved Supported Golgi apparatus
Cytosol Renal cancer:4.49e-5 (favourable), Breast cancer:9.07e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 33.2 WWP1 AIP5, DKFZP434D2111 ENSG00000123124 WW domain containing E3 ubiquitin protein ligase 1 8 86342738-86478420 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023180 Approved Approved Golgi apparatus
Plasma membrane
Cytosol Renal cancer:5.45e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 185.9 WWP2 AIP2 ENSG00000198373 WW domain containing E3 ubiquitin protein ligase 2 16 69762306-69941741 Predicted intracellular proteins Evidence at protein level Renal cancer:5.87e-11 (favourable) Expressed in all Expressed in all parathyroid gland: 48.8 XAB2 HCNP, HCRN, NTC90, SYF1 ENSG00000076924 XPA binding protein 2 19 7619525-7629565 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048751 Approved Nucleus
Vesicles Cervical cancer:4.04e-4 (favourable), Endometrial cancer:4.96e-4 (favourable), Pancreatic cancer:7.47e-4 (favourable) Expressed in all Expressed in all testis: 39.3 XBP1 XBP2 ENSG00000100219 X-box binding protein 1 22 28794555-28800597 Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level Not detected Expressed in all breast: 907.4 XIAP API3, BIRC4, hILP ENSG00000101966 X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase X 123859724-123913979 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009203, HPA042428 Approved Supported Nucleoplasm
Plasma membrane
Cytosol Breast cancer:9.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 35.0 XKR8 FLJ10307 ENSG00000158156 XK, Kell blood group complex subunit-related family, member 8 1 27959462-27968096 Predicted membrane proteins, Transporters Evidence at protein level HPA049984, HPA053529 Uncertain Approved Golgi apparatus Breast cancer:8.63e-4 (favourable) Expressed in all Expressed in all placenta: 13.6 XPA XP1, XPAC ENSG00000136936 Xeroderma pigmentosum, complementation group A 9 97674909-97697357 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level CAB000155, HPA056856 Supported Approved Nucleus
Cytokinetic bridge Renal cancer:4.28e-5 (favourable) Expressed in all Expressed in all thyroid gland: 38.9 XPC RAD4, XPCC ENSG00000154767 Xeroderma pigmentosum, complementation group C 3 14145147-14178783 Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB009932, HPA035707, HPA069673 Supported Validated Nucleus
Plasma membrane Renal cancer:4.14e-7 (favourable), Urothelial cancer:2.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 51.3 XPNPEP1 XPNPEP, XPNPEPL, XPNPEPL1 ENSG00000108039 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 10 109864766-109923553 Enzymes, Predicted intracellular proteins Evidence at protein level CAB025196, HPA030419, HPA030420, HPA030422 Supported Validated Cytosol Liver cancer:2.12e-5 (unfavourable) Expressed in all Expressed in all small intestine: 67.5 XPO1 CRM1, emb ENSG00000082898 Exportin 1 2 61477849-61538626 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level CAB010184, HPA042933 Supported Validated Nucleoplasm
Nuclear membrane
Vesicles
Cytosol Liver cancer:1.84e-5 (unfavourable), Renal cancer:3.74e-4 (unfavourable) Expressed in all Expressed in all testis: 138.5 XPO5 KIAA1291 ENSG00000124571 Exportin 5 6 43522330-43576075 Predicted intracellular proteins, Transporters Evidence at protein level CAB012357, HPA018402, HPA023959, HPA029909, HPA029910 Supported Validated Nucleoplasm Liver cancer:3.98e-8 (unfavourable), Endometrial cancer:4.94e-7 (unfavourable) Expressed in all Expressed in all testis: 43.4 XPO6 FLJ22519, KIAA0370, RANBP20 ENSG00000169180 Exportin 6 16 28097979-28211920 Predicted intracellular proteins Evidence at protein level HPA038246 Uncertain Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Liver cancer:3.68e-4 (unfavourable), Urothelial cancer:8.80e-4 (unfavourable) Expressed in all Expressed in all testis: 94.0 XPO7 KIAA0745, RANBP16 ENSG00000130227 Exportin 7 8 21919671-22006585 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA043727, HPA048153 Uncertain Approved Nucleus Colorectal cancer:2.29e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 77.3 XPOT XPO3 ENSG00000184575 Exportin, tRNA 12 64404350-64451127 Predicted intracellular proteins, Transporters Evidence at protein level HPA048067, HPA057602 Validated Nucleoplasm
Cytosol Renal cancer:2.41e-12 (unfavourable), Liver cancer:1.81e-7 (unfavourable), Urothelial cancer:5.79e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 82.9 XPR1 SYG1, X3 ENSG00000143324 Xenotropic and polytropic retrovirus receptor 1 1 180632004-180890251 Disease related genes, Predicted membrane proteins Evidence at protein level HPA016557 Supported Approved Endoplasmic reticulum
Golgi apparatus Liver cancer:3.04e-4 (unfavourable) Expressed in all Expressed in all testis: 31.1 XRCC1 RCC ENSG00000073050 X-ray repair complementing defective repair in Chinese hamster cells 1 19 43543040-43580473 Cancer-related genes, Predicted intracellular proteins Evidence at protein level CAB005427, HPA006717 Supported Validated Nucleoplasm Liver cancer:7.33e-5 (unfavourable) Expressed in all Expressed in all ovary: 34.6 XRCC3 ENSG00000126215 X-ray repair complementing defective repair in Chinese hamster cells 3 14 103697609-103715504 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA062422, HPA068953 Validated Nucleus Expressed in all Expressed in all skin: 46.0 XRCC5 KARP-1, KU80, Ku86, KUB2 ENSG00000079246 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 2 216107464-216206303 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004468, HPA025813, HPA064685 Supported Validated Nucleoplasm Liver cancer:2.10e-7 (unfavourable) Expressed in all Expressed in all thyroid gland: 212.5 XRCC6 D22S671, D22S731, G22P1, KU70, ML8 ENSG00000196419 X-ray repair complementing defective repair in Chinese hamster cells 6 22 41621119-41664048 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004254, HPA047549, HPA062226 Supported Validated Nucleoplasm Expressed in all Expressed in all testis: 395.0 XRN1 SEP1 ENSG00000114127 5'-3' exoribonuclease 1 3 142306607-142448062 Predicted intracellular proteins Evidence at protein level HPA035005, HPA035006 Approved Supported Plasma membrane
Cytosol Pancreatic cancer:9.43e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 21.9 XRN2 ENSG00000088930 5'-3' exoribonuclease 2 20 21303304-21389827 Predicted intracellular proteins Evidence at protein level HPA047118, HPA050485 Supported Validated Nucleus
Nucleoli Liver cancer:3.54e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.7 XYLT2 PXYLT2, XT-II ENSG00000015532 Xylosyltransferase II 17 50346092-50363138 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA016456 Approved Nuclear bodies
Cytosol Expressed in all Expressed in all stomach: 31.1 YAE1D1 C7orf36, GK003 ENSG00000241127 Yae1 domain containing 1 7 39566376-39610320 Predicted intracellular proteins Evidence at protein level HPA019226, HPA031249 Uncertain Approved Cytosol Liver cancer:1.64e-4 (unfavourable) Expressed in all Expressed in all testis: 34.3 YAF2 ENSG00000015153 YY1 associated factor 2 12 42157104-42238349 Predicted intracellular proteins Evidence at protein level HPA026867 Supported Supported Nucleoplasm Expressed in all Expressed in all cerebral cortex: 29.5 YARS tyrRS, YRS, YTS ENSG00000134684 Tyrosyl-tRNA synthetase 1 32775237-32818153 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA017936, HPA018950, HPA018954 Supported Validated Cytosol Renal cancer:1.02e-11 (unfavourable), Liver cancer:6.97e-11 (unfavourable), Urothelial cancer:6.57e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 81.7 YBEY C21orf57 ENSG00000182362 YbeY metallopeptidase (putative) 21 46286337-46297751 Predicted intracellular proteins Evidence at protein level HPA016593, HPA018162 Uncertain Validated Nucleoplasm Breast cancer:5.54e-4 (favourable) Expressed in all Expressed in all testis: 91.6 YBX1 BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1 ENSG00000065978 Y box binding protein 1 1 42682427-42702349 Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level CAB005875, HPA040304, HPA057159 Supported Validated Vesicles
Cytosol Liver cancer:9.87e-10 (unfavourable), Renal cancer:3.59e-7 (unfavourable) Expressed in all Expressed in all testis: 1538.1 YBX3 CSDA, CSDA1, dbpA, ZONAB ENSG00000060138 Y box binding protein 3 12 10699089-10723312 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034838 Approved Supported Cytosol Renal cancer:6.17e-13 (unfavourable) Expressed in all Expressed in all skeletal muscle: 1301.2 YEATS4 GAS41, NuBI-1, YAF9 ENSG00000127337 YEATS domain containing 4 12 69359703-69390796 Predicted intracellular proteins Evidence at protein level HPA072532 Approved Nucleoplasm
Nuclear membrane Liver cancer:3.52e-6 (unfavourable) Expressed in all Expressed in all testis: 68.8 YES1 c-yes, HsT441, Yes ENSG00000176105 YES proto-oncogene 1, Src family tyrosine kinase 18 721588-812546 Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB004370, HPA026480 Approved Supported Plasma membrane
Cytosol Pancreatic cancer:2.46e-4 (unfavourable) Expressed in all Expressed in all placenta: 61.6 YIF1A 54TM, FinGER7, YIF1, YIF1P ENSG00000174851 Yip1 interacting factor homolog A (S. cerevisiae) 11 66284580-66289170 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014840 Approved Supported Golgi apparatus
Vesicles
Microtubule organizing center Urothelial cancer:8.70e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 61.2 YIF1B FinGER8 ENSG00000167645 Yip1 interacting factor homolog B (S. cerevisiae) 19 38305104-38317273 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA039328, HPA055257, HPA062675 Approved Approved Golgi apparatus
Vesicles Liver cancer:4.53e-5 (unfavourable), Pancreatic cancer:1.88e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 49.6 YIPF1 DJ167A19.1, FinGER1 ENSG00000058799 Yip1 domain family, member 1 1 53851719-53889834 Predicted membrane proteins Evidence at protein level HPA014716 Approved Approved Nucleoplasm Liver cancer:1.34e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 42.1 YIPF2 FinGER2, MGC3262 ENSG00000130733 Yip1 domain family, member 2 19 10922185-10928681 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA019902 Approved Approved Golgi apparatus
Mitochondria Expressed in all Expressed in all testis: 73.3 YIPF3 C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1 ENSG00000137207 Yip1 domain family, member 3 6 43511827-43516990 Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA014859, HPA063699 Supported Validated Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 140.3 YIPF4 FinGER4, MGC11061 ENSG00000119820 Yip1 domain family, member 4 2 32277910-32316594 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA017884 Supported Supported Golgi apparatus
Vesicles
Plasma membrane Expressed in all Expressed in all cerebral cortex: 19.0 YIPF5 FinGER5, SMAP-5 ENSG00000145817 Yip1 domain family, member 5 5 144158159-144170714 Predicted membrane proteins Evidence at protein level HPA042338, HPA073622 Supported Supported Nucleoplasm
Endoplasmic reticulum
Golgi apparatus
Vesicles Head and neck cancer:1.12e-5 (unfavourable), Liver cancer:3.26e-5 (unfavourable), Breast cancer:7.83e-5 (unfavourable) Expressed in all Expressed in all placenta: 42.9 YIPF6 FinGER6, MGC21416 ENSG00000181704 Yip1 domain family, member 6 X 68498323-68537285 Predicted membrane proteins Evidence at protein level HPA003720 Uncertain Approved Vesicles Expressed in all Expressed in all thyroid gland: 32.7 YKT6 ENSG00000106636 YKT6 v-SNARE homolog (S. cerevisiae) 7 44200968-44214294 Predicted intracellular proteins Evidence at protein level HPA030817, HPA030818 Approved Approved Mitochondria
Cytosol Liver cancer:1.02e-4 (unfavourable), Head and neck cancer:4.64e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 62.0 YLPM1 C14orf170, PPP1R169, ZAP ENSG00000119596 YLP motif containing 1 14 74763366-74859435 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA048070, HPA061123 Uncertain Supported Nucleoplasm
Nuclear speckles Renal cancer:6.08e-7 (favourable) Expressed in all Expressed in all testis: 39.0 YME1L1 ENSG00000136758 YME1-like 1 ATPase 10 27110112-27155266 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA066953 Approved Supported Nuclear bodies
Mitochondria Liver cancer:8.25e-6 (unfavourable) Expressed in all Expressed in all thyroid gland: 105.3 YPEL2 FKSG4 ENSG00000175155 Yippee-like 2 17 59331689-59401729 Predicted intracellular proteins Evidence at protein level HPA030501, HPA045621 Uncertain Endometrial cancer:6.73e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 26.3 YPEL3 MGC10500 ENSG00000090238 Yippee-like 3 16 30092314-30096915 Predicted intracellular proteins Evidence at transcript level HPA030501, HPA045621 Uncertain Head and neck cancer:1.09e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 117.3 YPEL5 CGI-127 ENSG00000119801 Yippee-like 5 2 30146941-30160533 Predicted intracellular proteins Evidence at protein level HPA042809 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all bone marrow: 272.0 YRDC FLJ23476, IRIP, SUA5 ENSG00000196449 YrdC N(6)-threonylcarbamoyltransferase domain containing 1 37802944-37808185 Predicted intracellular proteins Evidence at protein level HPA030147 Approved Approved Mitochondria Liver cancer:1.83e-6 (unfavourable) Expressed in all Expressed in all bone marrow: 31.7 YTHDC1 KIAA1966, YT521, YT521-B ENSG00000083896 YTH domain containing 1 4 68310387-68350089 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036462 Supported Approved Nucleoplasm
Plasma membrane Urothelial cancer:7.29e-5 (favourable) Expressed in all Expressed in all bone marrow: 75.2 YTHDC2 DKFZp564A186, FLJ10053, FLJ2194 ENSG00000047188 YTH domain containing 2 5 113513683-113595285 Enzymes, Predicted intracellular proteins Evidence at protein level HPA037364, HPA072678 Approved Approved Nucleoplasm
Nuclear bodies
Cytoplasmic bodies Colorectal cancer:1.82e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 36.4 YTHDF1 C20orf21, FLJ20391 ENSG00000149658 YTH N(6)-methyladenosine RNA binding protein 1 20 63195429-63216234 Predicted intracellular proteins Evidence at protein level Liver cancer:1.65e-5 (unfavourable), Breast cancer:7.96e-4 (unfavourable), Thyroid cancer:9.60e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 42.3 YTHDF2 CAHL, HGRG8, NY-REN-2 ENSG00000198492 YTH N(6)-methyladenosine RNA binding protein 2 1 28736621-28769775 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054080, HPA059621 Approved Approved Cytosol Liver cancer:6.14e-9 (unfavourable) Expressed in all Expressed in all parathyroid gland: 57.8 YTHDF3 FLJ31657 ENSG00000185728 YTH N(6)-methyladenosine RNA binding protein 3 8 63168553-63212786 Predicted intracellular proteins Evidence at protein level HPA048703 Approved Nuclear membrane
Nuclear speckles
Cytosol Expressed in all Expressed in all bone marrow: 59.2 YWHAB YWHAA ENSG00000166913 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 20 44885676-44908532 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB003759, HPA007925, HPA011212 Supported Supported Cytosol Liver cancer:1.91e-6 (unfavourable), Renal cancer:2.52e-5 (favourable), Endometrial cancer:5.46e-4 (unfavourable), Lung cancer:6.01e-4 (unfavourable), Head and neck cancer:6.14e-4 (unfavourable), Breast cancer:9.18e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 446.4 YWHAE FLJ45465 ENSG00000108953 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 17 1344272-1400378 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA008445, CAB016200, CAB021109, CAB047350 Approved Uncertain Cytosol Endometrial cancer:6.48e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 452.9 YWHAG PPP1R170 ENSG00000170027 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 7 76326794-76359031 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB013274, CAB018389, HPA026918 Approved Renal cancer:4.01e-4 (unfavourable), Cervical cancer:4.53e-4 (unfavourable), Lung cancer:5.34e-4 (unfavourable), Pancreatic cancer:7.44e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 613.3 YWHAQ 14-3-3, HS1 ENSG00000134308 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2 9583972-9631014 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007925, CAB010286 Approved Supported Nucleoplasm
Cytosol Liver cancer:9.83e-6 (unfavourable), Endometrial cancer:8.20e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 399.2 YWHAZ 14-3-3-zeta, KCIP-1, YWHAD ENSG00000164924 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 8 100916525-100953388 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB005065 Approved Renal cancer:2.03e-6 (unfavourable), Pancreatic cancer:1.20e-5 (unfavourable), Liver cancer:2.28e-5 (unfavourable), Endometrial cancer:3.91e-4 (unfavourable), Lung cancer:3.93e-4 (unfavourable) Expressed in all Expressed in all esophagus: 928.6 YY1 DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1 ENSG00000100811 YY1 transcription factor 14 100238298-100282792 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001119, CAB009392 Supported Supported Nucleoplasm
Nucleoli fibrillar center
Vesicles Liver cancer:3.44e-4 (unfavourable), Endometrial cancer:6.13e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 65.8 YY1AP1 HCCA2, YAP, YY1AP ENSG00000163374 YY1 associated protein 1 1 155659443-155689000 Predicted intracellular proteins Evidence at protein level HPA006986, HPA064249 Uncertain Approved Nucleoli fibrillar center Renal cancer:2.01e-6 (unfavourable) Expressed in all Expressed in all testis: 129.5 ZADH2 MGC45594 ENSG00000180011 Zinc binding alcohol dehydrogenase domain containing 2 18 75195108-75209348 Predicted intracellular proteins Evidence at protein level HPA021468, HPA053646 Uncertain Approved Nucleus
Golgi apparatus
Vesicles Renal cancer:1.02e-6 (favourable), Thyroid cancer:1.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 51.9 ZBED1 ALTE, DREF, hDREF, KIAA0785, TRAMP ENSG00000214717 Zinc finger, BED-type containing 1 X 2486414-2500967 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA077591 Approved Nucleoplasm
Nuclear membrane
Centrosome Renal cancer:3.13e-4 (unfavourable) Expressed in all Expressed in all cervix, uterine: 24.5 ZBED4 KIAA0637 ENSG00000100426 Zinc finger, BED-type containing 4 22 49853842-49890078 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA045341 Approved Supported Nucleoplasm Expressed in all Expressed in all lymph node: 7.8 ZBED5 Buster1 ENSG00000236287 Zinc finger, BED-type containing 5 11 10812074-10858796 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048472, HPA050994 Uncertain Approved Nucleus
Nucleoli fibrillar center
Golgi apparatus Liver cancer:2.19e-5 (unfavourable), Urothelial cancer:3.87e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 94.8 ZBTB1 KIAA0997, ZNF909 ENSG00000126804 Zinc finger and BTB domain containing 1 14 64503712-64533690 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050516 Approved Supported Nucleoplasm
Nuclear membrane Head and neck cancer:4.92e-4 (favourable) Expressed in all Expressed in all bone marrow: 53.6 ZBTB10 FLJ12752, RINZF ENSG00000205189 Zinc finger and BTB domain containing 10 8 80485619-80526265 Predicted intracellular proteins Evidence at protein level HPA021554, HPA050569 Supported Validated Nucleoplasm Renal cancer:3.52e-4 (favourable) Expressed in all Expressed in all placenta: 25.8 ZBTB11 ZNF-U69274, ZNF913 ENSG00000066422 Zinc finger and BTB domain containing 11 3 101648889-101677495 Predicted intracellular proteins, Predicted membrane proteins, Transcription factors Evidence at protein level HPA015328, HPA024138 Approved Validated Nucleoplasm Endometrial cancer:7.49e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 23.5 ZBTB14 ZFP161, ZNF478 ENSG00000198081 Zinc finger and BTB domain containing 14 18 5289019-5297053 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050758, HPA070819 Uncertain Validated Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 29.3 ZBTB17 MIZ1, pHZ-67, ZNF151, ZNF60 ENSG00000116809 Zinc finger and BTB domain containing 17 1 15941869-15976132 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005789 Approved Liver cancer:2.38e-6 (unfavourable), Renal cancer:3.27e-5 (unfavourable), Urothelial cancer:2.04e-4 (favourable) Expressed in all Expressed in all testis: 21.9 ZBTB18 C2H2-171, RP58, TAZ-1, ZNF238 ENSG00000179456 Zinc finger and BTB domain containing 18 1 244048939-244057476 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044652 Supported Nucleoplasm
Microtubules
Cytokinetic bridge Urothelial cancer:6.78e-6 (favourable), Endometrial cancer:1.34e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 76.5 ZBTB2 bA351K16.2, KIAA1483, ZNF437 ENSG00000181472 Zinc finger and BTB domain containing 2 6 151364117-151391548 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023136, HPA023137, HPA023458, HPA023487 Approved Supported Nucleoplasm
Cytosol Renal cancer:9.36e-6 (unfavourable), Liver cancer:1.21e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 49.8 ZBTB33 kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348 ENSG00000177485 Zinc finger and BTB domain containing 33 X 120250752-120258398 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA000755, CAB001980, HPA005732 Approved Validated Nucleus
Plasma membrane
Cytosol Expressed in all Expressed in all parathyroid gland: 23.0 ZBTB38 CIBZ, FLJ35036, PPP1R171, ZNF921 ENSG00000177311 Zinc finger and BTB domain containing 38 3 141324213-141449792 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA014865, HPA059378 Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 129.7 ZBTB4 KAISO-L1, KIAA1538, ZNF903 ENSG00000174282 Zinc finger and BTB domain containing 4 17 7459366-7484263 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB008980, HPA064763 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Renal cancer:1.65e-9 (favourable), Pancreatic cancer:2.53e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 166.8 ZBTB40 KIAA0478, ZNF923 ENSG00000184677 Zinc finger and BTB domain containing 40 1 22451851-22531157 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042386 Approved Nucleus Liver cancer:7.78e-8 (unfavourable), Pancreatic cancer:4.12e-5 (favourable), Head and neck cancer:2.01e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 20.5 ZBTB43 FLJ22470, KIAA0414, ZBTB22B, ZNF-X, ZNF297B ENSG00000169155 Zinc finger and BTB domain containing 43 9 126805006-126838210 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016825 Approved Approved Nucleus
Nucleoli Renal cancer:8.73e-4 (favourable) Expressed in all Expressed in all bone marrow: 38.8 ZBTB44 BTBD15, HSPC063, ZNF851 ENSG00000196323 Zinc finger and BTB domain containing 44 11 130226677-130314686 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052589 Approved Approved Nucleoplasm Expressed in all Expressed in all testis: 75.4 ZBTB45 FLJ14486, ZNF499 ENSG00000119574 Zinc finger and BTB domain containing 45 19 58513530-58538911 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA035754 Uncertain Approved Cytosol Renal cancer:5.38e-4 (favourable) Expressed in all Expressed in all cerebral cortex,thyroid gland: 10.6 ZBTB47 DKFZp434N0615, KIAA1190, ZNF651 ENSG00000114853 Zinc finger and BTB domain containing 47 3 42653684-42665854 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA074057 Approved Nucleoplasm Renal cancer:7.96e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 48.0 ZBTB48 HKR3, ZNF855 ENSG00000204859 Zinc finger and BTB domain containing 48 1 6580001-6589280 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030417 Uncertain Approved Nucleoplasm
Cytosol Pancreatic cancer:5.19e-6 (favourable), Cervical cancer:1.04e-4 (favourable) Expressed in all Expressed in all testis: 32.9 ZBTB5 KIAA0354 ENSG00000168795 Zinc finger and BTB domain containing 5 9 37438114-37465399 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021521 Approved Approved Nucleoplasm
Nuclear bodies
Golgi apparatus Expressed in all Expressed in all thyroid gland: 17.6 ZBTB7A DKFZp547O146, FBI-1, LRF, pokemon, ZBTB7, ZNF857A ENSG00000178951 Zinc finger and BTB domain containing 7A 19 4044364-4066945 Predicted intracellular proteins, Transcription factors Evidence at protein level CAB037214, CAB037285, HPA046387 Supported Approved Nucleoplasm Renal cancer:1.34e-6 (favourable), Endometrial cancer:6.50e-6 (favourable), Stomach cancer:1.79e-4 (favourable), Pancreatic cancer:2.99e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 23.9 ZBTB7B c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B ENSG00000160685 Zinc finger and BTB domain containing 7B 1 155002630-155018522 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006811, HPA025820 Approved Validated Nucleoplasm Expressed in all Expressed in all skin: 89.6 ZBTB8OS ARCH ENSG00000176261 Zinc finger and BTB domain containing 8 opposite strand 1 32600172-32650903 Predicted intracellular proteins Evidence at protein level HPA046315 Approved Approved Plasma membrane Renal cancer:7.11e-8 (unfavourable), Liver cancer:4.25e-4 (unfavourable), Melanoma:8.56e-4 (unfavourable) Expressed in all Expressed in all lymph node: 42.9 ZC3H11A KIAA0663, ZC3HDC11A ENSG00000058673 Zinc finger CCCH-type containing 11A 1 203795654-203854124 Predicted intracellular proteins Evidence at protein level HPA026439, HPA028490, HPA028526 Approved Approved Nuclear speckles Renal cancer:5.58e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 113.9 ZC3H13 DKFZp434D1812, KIAA0853 ENSG00000123200 Zinc finger CCCH-type containing 13 13 45954465-46052759 Predicted intracellular proteins Evidence at protein level HPA039340, HPA040140, HPA047806 Uncertain Approved Nuclear membrane
Actin filaments Renal cancer:2.69e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 33.6 ZC3H14 FLJ11806, NY-REN-37, UKp68 ENSG00000100722 Zinc finger CCCH-type containing 14 14 88562909-88627596 Predicted intracellular proteins Evidence at protein level HPA049798, HPA053510 Supported Validated Nuclear speckles Renal cancer:7.08e-4 (favourable) Expressed in all Expressed in all testis: 325.8 ZC3H15 LEREPO4 ENSG00000065548 Zinc finger CCCH-type containing 15 2 186486156-186509363 Predicted intracellular proteins Evidence at protein level HPA031099, HPA031100, HPA031101 Supported Validated Cytosol Liver cancer:1.48e-7 (unfavourable), Cervical cancer:6.45e-5 (unfavourable), Ovarian cancer:3.98e-4 (favourable), Pancreatic cancer:9.75e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 78.2 ZC3H18 NHN1 ENSG00000158545 Zinc finger CCCH-type containing 18 16 88570381-88631966 Predicted intracellular proteins Evidence at protein level HPA040847, HPA041327 Supported Validated Nuclear speckles Renal cancer:3.68e-4 (favourable), Liver cancer:4.06e-4 (unfavourable) Expressed in all Expressed in all testis: 30.8 ZC3H3 KIAA0150, ZC3HDC3 ENSG00000014164 Zinc finger CCCH-type containing 3 8 143437655-143541453 Predicted intracellular proteins Evidence at protein level HPA023658, HPA050577 Uncertain Uncertain Nucleoplasm
Golgi apparatus Renal cancer:4.38e-7 (unfavourable), Liver cancer:4.06e-4 (unfavourable) Expressed in all Expressed in all testis: 13.5 ZC3H4 C19orf7, KIAA1064 ENSG00000130749 Zinc finger CCCH-type containing 4 19 47064187-47113752 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA040934, HPA041068 Supported Validated Nucleoplasm
Cytosol Urothelial cancer:2.23e-4 (favourable) Expressed in all Expressed in all spleen: 13.8 ZC3H7A FLJ20318, HSPC055, ZC3H7, ZC3HDC7 ENSG00000122299 Zinc finger CCCH-type containing 7A 16 11750586-11797267 Predicted intracellular proteins Evidence at protein level HPA040808, HPA059849 Uncertain Supported Cytosol Expressed in all Expressed in all parathyroid gland: 46.1 ZC3H7B DKFZp434K0920, FLJ13787, KIAA1031, RoXaN ENSG00000100403 Zinc finger CCCH-type containing 7B 22 41301522-41360147 Predicted intracellular proteins Evidence at protein level HPA001784 Uncertain Uncertain Cytosol Renal cancer:5.43e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 80.2 ZC3H8 Fliz1, ZC3HDC8 ENSG00000144161 Zinc finger CCCH-type containing 8 2 112211525-112255136 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034803, HPA034804 Approved Supported Nucleoplasm
Nuclear bodies Endometrial cancer:1.12e-6 (unfavourable), Renal cancer:1.89e-4 (unfavourable) Expressed in all Expressed in all testis: 16.2 ZC3HAV1 FLB6421, FLJ13288, MGC48898, PARP13, ZAP, ZC3H2, ZC3HDC2 ENSG00000105939 Zinc finger CCCH-type, antiviral 1 7 139043520-139109719 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA047818, HPA059096 Approved Validated Golgi apparatus
Cytosol Liver cancer:8.77e-7 (unfavourable), Stomach cancer:6.86e-4 (favourable) Expressed in all Expressed in all bone marrow: 54.7 ZC3HC1 NIPA ENSG00000091732 Zinc finger, C3HC-type containing 1 7 130018286-130051451 Predicted intracellular proteins Evidence at protein level HPA019089, HPA024023 Supported Supported Nucleus
Nuclear membrane Liver cancer:1.02e-6 (unfavourable), Endometrial cancer:3.36e-4 (unfavourable) Expressed in all Expressed in all testis: 26.4 ZCCHC10 FLJ20094 ENSG00000155329 Zinc finger, CCHC domain containing 10 5 132996985-133026604 Predicted intracellular proteins Evidence at protein level HPA038944 Approved Approved Nucleus
Nucleoli Expressed in all Expressed in all testis: 43.4 ZCCHC11 KIAA0191, PAPD3, TUT4 ENSG00000134744 Zinc finger, CCHC domain containing 11 1 52408282-52553487 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027412, HPA027973 Supported Supported Nucleoli
Cytosol Liver cancer:9.00e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 59.0 ZCCHC14 BDG29, MGC14139 ENSG00000140948 Zinc finger, CCHC domain containing 14 16 87406246-87492045 Predicted intracellular proteins Evidence at protein level HPA014122 Uncertain Nuclear membrane Renal cancer:1.47e-14 (favourable) Expressed in all Expressed in all testis: 61.6 ZCCHC17 HSPC251, pNO40, PS1D ENSG00000121766 Zinc finger, CCHC domain containing 17 1 31296982-31364953 Predicted intracellular proteins Evidence at protein level HPA053727 Supported Nuclear speckles Liver cancer:3.27e-4 (unfavourable) Expressed in all Expressed in all testis: 78.5 ZCCHC2 C18orf49, FLJ20222, FLJ20281, KIAA1744 ENSG00000141664 Zinc finger, CCHC domain containing 2 18 62523007-62587709 Predicted intracellular proteins Evidence at protein level HPA040943 Uncertain Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all testis: 22.3 ZCCHC24 C10orf56, FLJ90798, Z3CXXC8 ENSG00000165424 Zinc finger, CCHC domain containing 24 10 79382325-79445627 Predicted intracellular proteins Evidence at protein level HPA038348 Approved Approved Nucleoplasm
Mitochondria Renal cancer:5.35e-6 (unfavourable), Ovarian cancer:3.76e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 70.8 ZCCHC3 C20orf99, dJ1103G7.7 ENSG00000247315 Zinc finger, CCHC domain containing 3 20 296968-300321 Predicted intracellular proteins Evidence at protein level HPA042972 Approved Vesicles Pancreatic cancer:1.29e-4 (favourable) Expressed in all Expressed in all placenta: 23.0 ZCCHC6 FLJ13409, KIAA1711, PAPD6, TUT7 ENSG00000083223 Zinc finger, CCHC domain containing 6 9 86287733-86354454 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020615, HPA020620 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all prostate: 37.1 ZCCHC7 AIR1, FLJ22611 ENSG00000147905 Zinc finger, CCHC domain containing 7 9 37120539-37358149 Predicted intracellular proteins Evidence at protein level HPA020600, HPA021088, HPA029522 Uncertain Validated Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 28.8 ZCCHC8 DKFZp434E2220 ENSG00000033030 Zinc finger, CCHC domain containing 8 12 122471600-122501073 Cancer-related genes, Predicted intracellular proteins Evidence at protein level HPA037483, HPA037484 Supported Validated Nucleoplasm
Nuclear bodies Renal cancer:5.36e-4 (unfavourable), Melanoma:7.40e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 33.1 ZCCHC9 DKFZp761J139, PPP1R41 ENSG00000131732 Zinc finger, CCHC domain containing 9 5 81301590-81313297 Predicted intracellular proteins Evidence at protein level HPA038404, HPA057521 Uncertain Approved Intermediate filaments Expressed in all Expressed in all placenta: 27.3 ZCRB1 MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19 ENSG00000139168 Zinc finger CCHC-type and RNA binding motif 1 12 42312078-42326118 Predicted intracellular proteins Evidence at protein level Liver cancer:5.33e-7 (unfavourable), Renal cancer:1.37e-6 (unfavourable), Ovarian cancer:7.33e-4 (favourable) Expressed in all Expressed in all testis: 153.1 ZDHHC12 FLJ14524, ZNF400 ENSG00000160446 Zinc finger, DHHC-type containing 12 9 128720869-128724127 Enzymes, Predicted membrane proteins Evidence at transcript level HPA059339 Uncertain Approved Nucleoplasm Expressed in all Expressed in all small intestine: 36.5 ZDHHC16 APH2 ENSG00000171307 Zinc finger, DHHC-type containing 16 10 97446131-97457370 Enzymes, Predicted membrane proteins Evidence at protein level HPA039893, HPA040214 Uncertain Supported Nucleus
Nuclear membrane
Cytosol Expressed in all Expressed in all placenta: 31.3 ZDHHC17 HIP14, HYPH, KIAA0946 ENSG00000186908 Zinc finger, DHHC-type containing 17 12 76763588-76853696 Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA016807 Approved Supported Golgi apparatus
Vesicles
Cytosol Renal cancer:7.11e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 45.4 ZDHHC18 DKFZp667O2416 ENSG00000204160 Zinc finger, DHHC-type containing 18 1 26826710-26857602 Enzymes, Predicted membrane proteins Evidence at protein level HPA040234 Approved Approved Microtubules Renal cancer:1.36e-10 (unfavourable), Liver cancer:7.42e-7 (unfavourable), Glioma:9.53e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 75.3 ZDHHC2 ZNF372 ENSG00000104219 Zinc finger, DHHC-type containing 2 8 17156029-17224799 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA023331 Uncertain Renal cancer:3.24e-4 (favourable) Expressed in all Expressed in all thyroid gland: 53.5 ZDHHC20 FLJ25952 ENSG00000180776 Zinc finger, DHHC-type containing 20 13 21372573-21459370 Enzymes, Predicted membrane proteins Evidence at protein level HPA014483, HPA014702 Approved Uncertain Vesicles
Plasma membrane
Mitochondria Renal cancer:1.01e-4 (unfavourable), Pancreatic cancer:6.55e-4 (unfavourable) Expressed in all Expressed in all testis: 60.4 ZDHHC3 GODZ, ZNF373 ENSG00000163812 Zinc finger, DHHC-type containing 3 3 44915257-44976185 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB012465, HPA016616 Approved Approved Golgi apparatus Renal cancer:1.81e-8 (favourable), Liver cancer:1.37e-4 (unfavourable), Colorectal cancer:3.43e-4 (favourable) Expressed in all Expressed in all skin: 65.4 ZDHHC4 FLJ10479, ZNF374 ENSG00000136247 Zinc finger, DHHC-type containing 4 7 6577434-6589374 Enzymes, Predicted membrane proteins Evidence at protein level HPA032124, HPA064358 Approved Approved Nuclear bodies Renal cancer:1.18e-7 (favourable), Head and neck cancer:3.95e-6 (unfavourable), Urothelial cancer:8.94e-4 (unfavourable), Cervical cancer:9.35e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 77.5 ZDHHC5 KIAA1748, ZNF375 ENSG00000156599 Zinc finger, DHHC-type containing 5 11 57667747-57701187 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014670 Approved Approved Nucleoplasm
Plasma membrane
Cell Junctions
Cytosol Pancreatic cancer:6.74e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 86.1 ZDHHC6 FLJ21952, ZNF376 ENSG00000023041 Zinc finger, DHHC-type containing 6 10 112424428-112446917 Enzymes, Predicted membrane proteins Evidence at protein level HPA014357 Approved Expressed in all Expressed in all small intestine: 51.7 ZDHHC7 FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370 ENSG00000153786 Zinc finger, DHHC-type containing 7 16 84974181-85011535 Enzymes, Predicted membrane proteins Evidence at protein level HPA019215, HPA059054, HPA059642 Uncertain Validated Golgi apparatus Renal cancer:1.12e-5 (favourable), Liver cancer:4.20e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 63.6 ZDHHC8 KIAA1292, ZNF378 ENSG00000099904 Zinc finger, DHHC-type containing 8 22 20129456-20148007 Enzymes, Predicted membrane proteins Evidence at protein level HPA003422 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:4.04e-4 (unfavourable), Cervical cancer:9.68e-4 (unfavourable) Expressed in all Expressed in all spleen: 30.2 ZDHHC9 CGI-89, CXorf11, ZDHHC10, ZNF379, ZNF380 ENSG00000188706 Zinc finger, DHHC-type containing 9 X 129803288-129843909 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA031814 Uncertain Supported Golgi apparatus
Cytosol Cervical cancer:4.64e-5 (unfavourable), Breast cancer:9.77e-5 (unfavourable), Head and neck cancer:2.45e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 71.2 ZEB2 KIAA0569, SIP-1, SIP1, ZFHX1B ENSG00000169554 Zinc finger E-box binding homeobox 2 2 144384081-144524583 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003456 Approved Approved Nucleus
Nucleoli
Cytosol Renal cancer:6.04e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 95.9 ZER1 C9orf60, Hzyg, ZYG, ZYG11BL ENSG00000160445 Zyg-11 related, cell cycle regulator 9 128729786-128772414 Predicted intracellular proteins Evidence at protein level HPA048464 Approved Cytosol Renal cancer:5.15e-11 (favourable), Cervical cancer:1.18e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 71.7 ZFAND1 FLJ14007 ENSG00000104231 Zinc finger, AN1-type domain 1 8 81701334-81732903 Predicted intracellular proteins Evidence at protein level HPA023383 Approved Approved Centrosome
Cytosol Expressed in all Expressed in all thyroid gland: 92.2 ZFAND2A AIRAP ENSG00000178381 Zinc finger, AN1-type domain 2A 7 1152071-1160759 Predicted intracellular proteins Evidence at transcript level HPA019469 Approved Renal cancer:5.47e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 50.1 ZFAND2B AIRAPL ENSG00000158552 Zinc finger, AN1-type domain 2B 2 219195237-219209651 Predicted intracellular proteins Evidence at protein level HPA035159, HPA035160 Uncertain Approved Nucleus
Nucleoli
Cytosol Pancreatic cancer:9.38e-4 (favourable) Expressed in all Expressed in all thyroid gland: 68.1 ZFAND3 FLJ13222, TEX27 ENSG00000156639 Zinc finger, AN1-type domain 3 6 37819499-38154624 Predicted intracellular proteins Evidence at protein level HPA016755 Approved Approved Nucleoplasm
Vesicles Expressed in all Expressed in all testis: 184.1 ZFAND5 ZA20D2, ZFAND5A, ZNF216 ENSG00000107372 Zinc finger, AN1-type domain 5 9 72351425-72365235 Predicted intracellular proteins Evidence at protein level HPA018129 Approved Approved Nucleoplasm
Cytosol Endometrial cancer:4.43e-4 (favourable) Expressed in all Expressed in all adipose tissue: 309.5 ZFAND6 AWP1, ZA20D3, ZFAND5B ENSG00000086666 Zinc finger, AN1-type domain 6 15 80059568-80138393 Predicted intracellular proteins Evidence at protein level HPA034845 Uncertain Urothelial cancer:8.20e-4 (favourable) Expressed in all Expressed in all testis: 246.4 ZFP36 G0S24, NUP475, RNF162A, TIS11, TTP ENSG00000128016 ZFP36 ring finger protein 19 39406813-39409412 Predicted intracellular proteins Evidence at transcript level HPA006009 Approved Approved Vesicles Expressed in all Expressed in all gallbladder: 931.9 ZFP36L1 Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B ENSG00000185650 ZFP36 ring finger protein-like 1 14 68787660-68796253 Cancer-related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA001301 Uncertain Expressed in all Expressed in all endometrium: 580.8 ZFP36L2 BRF2, ERF2, RNF162C, TIS11D ENSG00000152518 ZFP36 ring finger protein-like 2 2 43222402-43226609 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA047428 Approved Expressed in all Expressed in all thyroid gland: 273.3 ZFP62 FLJ34231, ZET, ZNF755 ENSG00000196670 ZFP62 zinc finger protein 5 180847611-180861285 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048629 Approved Approved Nucleoplasm
Actin filaments Expressed in all Expressed in all thyroid gland: 39.5 ZFP64 dJ548G19.1, dJ831D17.1, FLJ10734, FLJ12628, ZNF338 ENSG00000020256 ZFP64 zinc finger protein 20 52051663-52204308 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035112, HPA058387 Uncertain Approved Nucleus Liver cancer:9.86e-7 (unfavourable) Expressed in all Expressed in all skin: 13.9 ZFP91 PZF, ZNF757 ENSG00000186660 ZFP91 zinc finger protein 11 58579111-58621042 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024037, CAB025417, HPA065325 Approved Supported Nucleus
Nucleoli Pancreatic cancer:3.74e-6 (unfavourable) Expressed in all Expressed in all testis: 175.0 ZFPL1 D11S750, MCG4 ENSG00000162300 Zinc finger protein-like 1 11 65084223-65088400 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA014909, HPA017347 Supported Validated Golgi apparatus Liver cancer:9.12e-6 (unfavourable), Renal cancer:2.73e-5 (favourable) Expressed in all Expressed in all fallopian tube: 31.5 ZFR SPG71, ZFR1 ENSG00000056097 Zinc finger RNA binding protein 5 32354350-32444761 Predicted intracellular proteins Evidence at protein level HPA016666 Supported Approved Nucleoplasm Liver cancer:4.75e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 77.7 ZFX ZNF926 ENSG00000005889 Zinc finger protein, X-linked X 24149173-24216255 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001748, HPA003877, HPA071863 Supported Approved Nucleoplasm
Nucleoli Expressed in all Expressed in all parathyroid gland: 32.5 ZFYVE1 DFCP1, KIAA1589, PPP1R172, TAFF1, ZNFN2A1 ENSG00000165861 Zinc finger, FYVE domain containing 1 14 72969451-73027212 Predicted intracellular proteins Evidence at protein level HPA002898 Approved Renal cancer:5.07e-12 (favourable) Expressed in all Expressed in all testis: 22.6 ZFYVE19 ANCHR, FLJ14840 ENSG00000166140 Zinc finger, FYVE domain containing 19 15 40807086-40815084 Disease related genes, Predicted intracellular proteins Evidence at protein level HPA040283, HPA041946 Uncertain Endometrial cancer:7.36e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 27.7 ZFYVE21 MGC2550, ZF21 ENSG00000100711 Zinc finger, FYVE domain containing 21 14 103715730-103733668 Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA055721 Uncertain Renal cancer:2.58e-6 (favourable) Expressed in all Expressed in all endometrium: 88.3 ZFYVE27 FLJ32919, SPG33 ENSG00000155256 Zinc finger, FYVE domain containing 27 10 97737121-97760907 Disease related genes, Predicted membrane proteins Evidence at protein level HPA037523, HPA069876 Approved Approved Nucleoplasm
Cytosol Colorectal cancer:6.91e-4 (unfavourable), Stomach cancer:7.54e-4 (favourable), Urothelial cancer:7.80e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 33.4 ZGPAT dJ583P15.3, FLJ14972, GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP ENSG00000197114 Zinc finger, CCCH-type with G patch domain 20 63707465-63736142 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056705 Supported Nucleus
Plasma membrane Head and neck cancer:6.17e-5 (favourable) Expressed in all Expressed in all liver: 26.9 ZHX1 ENSG00000165156 Zinc fingers and homeoboxes 1 8 123248451-123275541 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055357, HPA060251 Validated Nucleoplasm Endometrial cancer:6.09e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 62.7 ZHX2 KIAA0854 ENSG00000178764 Zinc fingers and homeoboxes 2 8 122781394-122974512 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006769, HPA006996 Supported Expressed in all Expressed in all ovary: 32.7 ZHX3 KIAA0395, TIX1 ENSG00000174306 Zinc fingers and homeoboxes 3 20 41178448-41317672 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046498 Supported Nucleoplasm Urothelial cancer:1.84e-5 (unfavourable), Renal cancer:2.53e-5 (favourable), Endometrial cancer:1.62e-4 (unfavourable), Thyroid cancer:7.52e-4 (unfavourable) Expressed in all Expressed in all testis: 43.3 ZKSCAN1 KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33 ENSG00000106261 Zinc finger with KRAB and SCAN domains 1 7 100015572-100041689 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006672 Uncertain Approved Nucleus
Nuclear bodies
Mitochondria Expressed in all Expressed in all skin: 39.1 ZKSCAN8 LD5-1, ZNF192, ZSCAN40 ENSG00000198315 Zinc finger with KRAB and SCAN domains 8 6 28141910-28159472 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003483 Approved Approved Nucleus
Cytosol Endometrial cancer:1.33e-4 (unfavourable) Expressed in all Expressed in all endometrium: 24.8 ZMAT2 FLJ31121, hSNU23, Snu23 ENSG00000146007 Zinc finger, matrin-type 2 5 140698680-140706676 Predicted intracellular proteins Evidence at protein level HPA036518 Approved Approved Nucleus
Mitochondria Colorectal cancer:7.96e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 103.6 ZMAT5 SNRNP20, ZC3H19 ENSG00000100319 Zinc finger, matrin-type 5 22 29730956-29767011 Predicted intracellular proteins Evidence at protein level HPA004858 Approved Supported Nucleoplasm Expressed in all Expressed in all fallopian tube: 35.1 ZMIZ1 FLJ13541, hZIMP10, KIAA1224, MIZ, RAI17, RP11-519K18.1, Zimp10 ENSG00000108175 Zinc finger, MIZ-type containing 1 10 79069035-79316528 Predicted intracellular proteins Evidence at protein level HPA045144 Approved Approved Nucleoplasm
Vesicles Renal cancer:3.64e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 65.5 ZMIZ2 DKFZp761I2123, hZIMP7, KIAA1886, NET27, ZIMP7 ENSG00000122515 Zinc finger, MIZ-type containing 2 7 44748581-44769881 Predicted intracellular proteins Evidence at protein level HPA040716 Supported Supported Nucleoplasm Liver cancer:6.82e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 40.9 ZMPSTE24 FACE-1, HGPS, PRO1, STE24, Ste24p ENSG00000084073 Zinc metallopeptidase STE24 1 40258107-40294184 Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters Evidence at protein level HPA006988 Approved Approved Golgi apparatus
Cytosol Liver cancer:5.73e-6 (unfavourable), Thyroid cancer:6.34e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 89.0 ZMYM2 FIM, MYM, RAMP, ZNF198 ENSG00000121741 Zinc finger, MYM-type 2 13 19958670-20091829 Cancer-related genes, Disease related genes, Predicted intracellular proteins Evidence at protein level HPA031765 Approved Approved Nucleoplasm
Endoplasmic reticulum Urothelial cancer:6.07e-4 (favourable) Expressed in all Expressed in all testis: 87.6 ZMYM3 DXS6673E, KIAA0385, MYM, ZNF198L2, ZNF261 ENSG00000147130 Zinc finger, MYM-type 3 X 71239624-71255146 Disease related genes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA003211 Approved Approved Nucleoplasm Liver cancer:5.18e-4 (unfavourable) Expressed in all Expressed in all ovary: 43.8 ZMYM4 KIAA0425, MYM, ZNF198L3, ZNF262 ENSG00000146463 Zinc finger, MYM-type 4 1 35268967-35422058 Predicted intracellular proteins Evidence at protein level HPA051301, HPA054802 Approved Supported Nucleoplasm
Cytosol Liver cancer:9.75e-9 (unfavourable), Renal cancer:8.10e-4 (unfavourable) Expressed in all Expressed in all testis: 63.6 ZMYM5 MYM, ZNF198L1, ZNF237 ENSG00000132950 Zinc finger, MYM-type 5 13 19823482-19863636 Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA020879 Uncertain Expressed in all Expressed in all testis: 44.2 ZMYM6NB ENSG00000243749 ZMYM6 neighbor 1 34981535-34985353 Predicted membrane proteins Evidence at protein level HPA051024 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all placenta: 90.9 ZMYND11 BS69 ENSG00000015171 Zinc finger, MYND-type containing 11 10 134465-254637 Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA015816 Supported Nucleoplasm Renal cancer:4.76e-7 (favourable) Expressed in all Expressed in all parathyroid gland: 196.6 ZMYND19 MIZIP ENSG00000165724 Zinc finger, MYND-type containing 19 9 137582079-137590490 Predicted intracellular proteins Evidence at protein level HPA020642, HPA050761 Supported Approved Golgi apparatus
Vesicles Liver cancer:1.70e-4 (unfavourable) Expressed in all Expressed in all testis: 46.2 ZMYND8 PRKCBP1, RACK7 ENSG00000101040 Zinc finger, MYND-type containing 8 20 47209214-47356889 Predicted intracellular proteins Evidence at protein level HPA020949 Approved Approved Nucleoplasm
Golgi apparatus Renal cancer:7.06e-5 (unfavourable), Breast cancer:2.56e-4 (unfavourable), Liver cancer:2.62e-4 (unfavourable) Expressed in all Expressed in all epididymis: 39.8 ZNF10 KOX1 ENSG00000256223 Zinc finger protein 10 12 133130575-133159465 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003204 Uncertain Approved Nucleus
Vesicles
Plasma membrane Expressed in all Expressed in all parathyroid gland: 40.2 ZNF106 SH3BP3, ZFP106, ZNF474 ENSG00000103994 Zinc finger protein 106 15 42412823-42491123 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA054267 Approved Approved Nucleus
Nucleoli
Cytosol Expressed in all Expressed in all skeletal muscle: 144.2 ZNF12 GIOT-3, KOX3, ZNF325 ENSG00000164631 Zinc finger protein 12 7 6688433-6706923 Predicted intracellular proteins Evidence at protein level HPA063402 Supported Nucleoplasm
Centrosome Expressed in all Expressed in all parathyroid gland: 30.7 ZNF121 D19S204, ZHC32, ZNF20 ENSG00000197961 Zinc finger protein 121 19 9560353-9584533 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054961 Uncertain Uncertain Nucleoplasm
Nucleoli
Centrosome Urothelial cancer:5.75e-5 (favourable), Ovarian cancer:6.59e-5 (favourable), Renal cancer:1.01e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 23.1 ZNF131 pHZ-10, ZBTB35 ENSG00000172262 Zinc finger protein 131 5 43065176-43192021 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007023, HPA027748, HPA074630 Approved Validated Nucleoplasm
Intermediate filaments Liver cancer:1.56e-4 (unfavourable) Expressed in all Expressed in all testis: 59.1 ZNF133 pHZ-13, pHZ-66, ZNF150 ENSG00000125846 Zinc finger protein 133 20 18288283-18316996 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001493 Supported Approved Nucleus
Vesicles Liver cancer:4.46e-6 (unfavourable), Renal cancer:2.20e-5 (unfavourable) Expressed in all Expressed in all epididymis: 19.7 ZNF134 pHZ-15 ENSG00000213762 Zinc finger protein 134 19 57614233-57624723 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009064 Supported Approved Nucleoplasm Cervical cancer:1.03e-4 (unfavourable), Renal cancer:2.61e-4 (favourable), Head and neck cancer:5.21e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 25.2 ZNF140 pHZ-39 ENSG00000196387 Zinc finger protein 140 12 133079838-133107544 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA048332 Uncertain Expressed in all Expressed in all endometrium: 14.5 ZNF142 KIAA0236, pHZ-49 ENSG00000115568 Zinc finger protein 142 2 218637916-218659655 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049594 Uncertain Approved Nucleus
Nucleoli fibrillar center Liver cancer:1.35e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 15.0 ZNF143 pHZ-1, SBF, STAF ENSG00000166478 Zinc finger protein 143 11 9460319-9528524 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003263, HPA074818 Supported Approved Nucleoplasm
Nuclear bodies
Vesicles Liver cancer:1.76e-5 (unfavourable), Renal cancer:6.78e-4 (unfavourable) Expressed in all Expressed in all testis: 31.5 ZNF146 OZF ENSG00000167635 Zinc finger protein 146 19 36214602-36238774 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003358 Supported Supported Nucleoli Expressed in all Expressed in all parathyroid gland: 62.1 ZNF148 BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148 ENSG00000163848 Zinc finger protein 148 3 125225561-125375354 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001656, CAB017486 Supported Supported Nucleus
Golgi apparatus Pancreatic cancer:2.88e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 50.2 ZNF16 KOX9 ENSG00000170631 Zinc finger protein 16 8 144930358-144950888 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035782, HPA061835 Uncertain Supported Nucleus
Nucleoli Head and neck cancer:2.39e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 16.0 ZNF160 F11, FLJ00032, HKr18, HZF5, KIAA1611, KR18 ENSG00000170949 Zinc finger protein 160 19 53066606-53103436 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA023599 Uncertain Approved Nuclear speckles
Cytosol Urothelial cancer:2.67e-5 (favourable) Expressed in all Expressed in all spleen: 38.0 ZNF174 ZSCAN8 ENSG00000103343 Zinc finger protein 174 16 3401235-3409370 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA009656 Approved Supported Nucleoplasm
Actin filaments
Cytosol Expressed in all Expressed in all parathyroid gland: 27.7 ZNF18 HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38 ENSG00000154957 Zinc finger protein 18 17 11977439-11997510 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006144 Uncertain Approved Nucleoplasm
Golgi apparatus
Plasma membrane
Cytosol Renal cancer:3.06e-6 (unfavourable), Pancreatic cancer:5.12e-6 (favourable), Cervical cancer:6.32e-4 (favourable) Expressed in all Expressed in all testis: 22.2 ZNF181 HHZ181, MGC44316 ENSG00000197841 Zinc finger protein 181 19 34734155-34745378 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA043701, HPA062305 Uncertain Approved Nucleus Pancreatic cancer:1.05e-4 (favourable), Melanoma:2.60e-4 (unfavourable), Urothelial cancer:5.45e-4 (favourable) Expressed in all Expressed in all ovary: 21.6 ZNF189 ENSG00000136870 Zinc finger protein 189 9 101398873-101410660 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA034814 Uncertain Approved Intermediate filaments Renal cancer:5.32e-4 (favourable) Expressed in all Expressed in all epididymis: 102.8 ZNF19 KOX12, MGC51021 ENSG00000157429 Zinc finger protein 19 16 71464555-71565089 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA053189, HPA063685 Uncertain Approved Mitochondria Mixed Expressed in all testis: 32.3 ZNF195 ENSG00000005801 Zinc finger protein 195 11 3339261-3379222 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030605 Uncertain Approved Nucleus
Cytosol Urothelial cancer:4.79e-7 (favourable), Liver cancer:3.53e-5 (unfavourable), Renal cancer:7.89e-5 (unfavourable), Prostate cancer:4.24e-4 (unfavourable) Expressed in all Expressed in all epididymis: 21.2 ZNF202 ZKSCAN10, ZSCAN42 ENSG00000166261 Zinc finger protein 202 11 123724177-123741675 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA061946 Supported Nucleoplasm
Mitochondria Renal cancer:9.93e-7 (unfavourable), Liver cancer:2.52e-6 (unfavourable) Expressed in all Expressed in all testis: 16.7 ZNF205 Zfp13, ZNF210 ENSG00000122386 Zinc finger protein 205 16 3112560-3120517 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001791 Uncertain Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 17.1 ZNF207 ENSG00000010244 Zinc finger protein 207 17 32350117-32381886 Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA017013, HPA063908 Supported Validated Nucleus Renal cancer:4.17e-8 (unfavourable), Liver cancer:7.30e-8 (unfavourable), Colorectal cancer:2.81e-4 (favourable) Expressed in all Expressed in all bone marrow: 151.6 ZNF211 CH2H2-25, ZNF-25 ENSG00000121417 Zinc finger protein 211 19 57630395-57642779 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA011340, HPA049967 Approved Approved Mitochondria
Rods & Rings Expressed in all Expressed in all parathyroid gland: 32.1 ZNF212 C2H2-150 ENSG00000170260 Zinc finger protein 212 7 149239651-149255609 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049807, HPA054178 Uncertain Supported Nucleus Expressed in all Expressed in all testis: 15.4 ZNF219 ENSG00000165804 Zinc finger protein 219 14 21090046-21104722 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030761, HPA056168 Approved Supported Nucleus Expressed in all Expressed in all skin: 44.0 ZNF22 HKR-T1, KOX15, Zfp422, ZNF422 ENSG00000165512 Zinc finger protein 22 10 45000475-45005326 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016736, HPA054893 Approved Validated Nucleus Renal cancer:1.11e-5 (unfavourable), Stomach cancer:8.06e-4 (unfavourable) Expressed in all Expressed in all placenta: 46.6 ZNF224 BMZF-2, KOX22, ZNF255, ZNF27 ENSG00000267680 Zinc finger protein 224 19 44094339-44109886 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054045 Approved Supported Nucleus
Nuclear membrane Urothelial cancer:1.53e-7 (favourable), Renal cancer:5.32e-4 (unfavourable) Expressed in all Expressed in all spleen: 36.1 ZNF226 ENSG00000167380 Zinc finger protein 226 19 44165073-44178381 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006145, CAB034353 Uncertain Approved Nuclear bodies Urothelial cancer:2.37e-5 (favourable), Pancreatic cancer:8.34e-4 (favourable) Expressed in all Expressed in all thyroid gland: 39.7 ZNF227 ENSG00000131115 Zinc finger protein 227 19 44207547-44237268 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030573 Uncertain Approved Plasma membrane Urothelial cancer:2.64e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 18.4 ZNF24 KOX17, Zfp191, ZNF191, ZSCAN3 ENSG00000172466 Zinc finger protein 24 18 35332212-35345482 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024062, CAB025642 Supported Supported Nucleus Renal cancer:1.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 56.2 ZNF250 MGC9718, ZFP647, ZNF647 ENSG00000196150 Zinc finger protein 250 8 144876497-144902168 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020853 Uncertain Supported Nuclear speckles Renal cancer:2.43e-7 (favourable), Urothelial cancer:8.26e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.1 ZNF263 FPM315, ZKSCAN12, ZSCAN44 ENSG00000006194 Zinc finger protein 263 16 3263800-3301401 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035085, HPA035086 Uncertain Supported Nucleoplasm
Mitotic spindle
Cytosol Expressed in all Expressed in all parathyroid gland: 60.7 ZNF264 KIAA0412 ENSG00000083844 Zinc finger protein 264 19 57191500-57222846 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057665 Uncertain Expressed in all Expressed in all testis: 18.3 ZNF266 HZF1 ENSG00000174652 Zinc finger protein 266 19 9412598-9435578 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026836, HPA054110 Uncertain Validated Nucleus
Vesicles
Rods & Rings Head and neck cancer:3.94e-6 (favourable), Pancreatic cancer:3.03e-5 (favourable), Urothelial cancer:9.15e-5 (favourable), Cervical cancer:1.41e-4 (favourable), Renal cancer:1.82e-4 (unfavourable), Lung cancer:4.47e-4 (favourable) Expressed in all Expressed in all epididymis: 115.7 ZNF274 ZKSCAN19, ZSCAN51 ENSG00000171606 Zinc finger protein 274 19 58183029-58213562 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028880 Uncertain Supported Nucleus
Centrosome Prostate cancer:1.75e-4 (unfavourable), Glioma:4.26e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.6 ZNF275 ENSG00000063587 Zinc finger protein 275 X 153334155-153360110 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA000566 Approved Approved Nucleoli Expressed in all Expressed in all adrenal gland: 79.7 ZNF276 CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477 ENSG00000158805 Zinc finger protein 276 16 89720400-89740903 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021309, HPA022255 Uncertain Approved Nucleus
Nucleoli
Plasma membrane
Cytosol Renal cancer:3.37e-4 (unfavourable) Expressed in all Expressed in all spleen: 23.2 ZNF277 NRIF4, ZNF277P ENSG00000198839 Zinc finger protein 277 7 112206588-112343096 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027307 Uncertain Approved Nucleoplasm
Plasma membrane Renal cancer:9.47e-4 (favourable) Expressed in all Expressed in all thyroid gland: 33.4 ZNF280D FLJ20086, SUHW4, ZNF634 ENSG00000137871 Zinc finger protein 280D 15 56630181-56918571 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030233 Approved Approved Nucleoplasm
Golgi apparatus
Centrosome
Cytosol Expressed in all Expressed in all endometrium: 31.6 ZNF281 ZBP-99 ENSG00000162702 Zinc finger protein 281 1 200404940-200410056 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051228 Uncertain Validated Nucleoplasm Renal cancer:2.60e-5 (unfavourable), Cervical cancer:1.16e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 21.5 ZNF282 HUB1 ENSG00000170265 Zinc finger protein 282 7 149195485-149226248 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024374 Supported Approved Nucleoplasm
Cytosol Liver cancer:3.03e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 14.8 ZNF292 bA393I2.3, KIAA0530, ZFP292, Zn-15, Zn-16 ENSG00000188994 Zinc finger protein 292 6 87152833-87264196 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA032154, HPA050618 Uncertain Approved Nucleus
Nuclear membrane Expressed in all Expressed in all endometrium,ovary: 17.0 ZNF3 A8-51, FLJ20216, HF.12, KOX25, PP838, Zfp113 ENSG00000166526 Zinc finger protein 3 7 100064033-100082548 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003719 Supported Approved Approved Nucleoplasm Melanoma:1.59e-4 (unfavourable), Urothelial cancer:2.20e-4 (favourable), Lung cancer:5.73e-4 (favourable) Expressed in all Expressed in all fallopian tube: 55.2 ZNF302 ZNF135L, ZNF140L, ZNF327 ENSG00000089335 Zinc finger protein 302 19 34677639-34686397 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059503 Approved Vesicles
Cytokinetic bridge Endometrial cancer:2.03e-5 (unfavourable), Urothelial cancer:9.85e-5 (favourable), Renal cancer:5.41e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 41.4 ZNF316 ENST00000305834, MZF-3 ENSG00000205903 Zinc finger protein 316 7 6637322-6656432 Predicted intracellular proteins, Transcription factors Evidence at protein level Pancreatic cancer:6.03e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 50.0 ZNF317 ENSG00000130803 Zinc finger protein 317 19 9140380-9163424 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042075, HPA048625 Approved Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 20.4 ZNF318 HRIHFB2436, ZFP318 ENSG00000171467 Zinc finger protein 318 6 43307134-43369478 Predicted intracellular proteins Evidence at protein level HPA027022, HPA027031 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 49.4 ZNF32 KOX30 ENSG00000169740 Zinc finger protein 32 10 43643859-43648856 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA039148, HPA059640 Supported Nucleoplasm
Nuclear bodies Pancreatic cancer:3.02e-4 (favourable), Liver cancer:7.08e-4 (unfavourable) Expressed in all Expressed in all epididymis: 70.7 ZNF326 FLJ20403, ZAN75, Zfp326, ZIRD ENSG00000162664 Zinc finger protein 326 1 89995112-90035531 Predicted intracellular proteins Evidence at protein level HPA028450, HPA028461, HPA028466 Supported Validated Nucleoplasm
Golgi apparatus
Vesicles Urothelial cancer:2.84e-4 (favourable), Breast cancer:9.46e-4 (favourable) Expressed in all Expressed in all bone marrow: 29.5 ZNF330 HSA6591, NOA36 ENSG00000109445 Zinc finger protein 330 4 141220887-141234697 Predicted intracellular proteins Evidence at protein level HPA015705, HPA056325 Uncertain Supported Nucleoli Prostate cancer:3.66e-6 (unfavourable), Renal cancer:7.27e-6 (favourable) Expressed in all Expressed in all heart muscle: 64.0 ZNF331 RITA, ZNF361, ZNF463 ENSG00000130844 Zinc finger protein 331 19 53520981-53580269 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063157 Approved Nucleoplasm Stomach cancer:4.79e-4 (unfavourable), Thyroid cancer:7.43e-4 (unfavourable) Expressed in all Expressed in all adrenal gland: 210.3 ZNF335 bA465L10.2, NIF-1 ENSG00000198026 Zinc finger protein 335 20 45948653-45972172 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA063999, HPA071230 Validated Nucleoplasm Renal cancer:2.77e-5 (unfavourable), Liver cancer:1.59e-4 (unfavourable), Head and neck cancer:4.48e-4 (favourable), Prostate cancer:7.04e-4 (unfavourable) Expressed in all Expressed in all skin: 24.7 ZNF337 dJ694B14.1 ENSG00000130684 Zinc finger protein 337 20 25674215-25696841 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044303, HPA064219 Uncertain Approved Nuclear speckles
Plasma membrane Renal cancer:2.87e-6 (unfavourable) Mixed Expressed in all parathyroid gland: 28.7 ZNF33A FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK ENSG00000189180 Zinc finger protein 33A 10 38010650-38065088 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005538, HPA056638 Approved Uncertain Nucleoli
Endoplasmic reticulum Expressed in all Expressed in all parathyroid gland: 34.5 ZNF33B KOX2, KOX31, ZNF11B ENSG00000196693 Zinc finger protein 33B 10 42574185-42638568 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005538, HPA056638 Approved Uncertain Nucleoli
Endoplasmic reticulum Expressed in all Expressed in all fallopian tube: 31.9 ZNF34 KOX32 ENSG00000196378 Zinc finger protein 34 8 144773114-144787345 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA053925, HPA060755, HPA066805 Uncertain Validated Nucleoplasm
Cytosol Expressed in all Expressed in all ovary: 12.8 ZNF346 JAZ, Zfp346 ENSG00000113761 Zinc finger protein 346 5 177022696-177081189 Predicted intracellular proteins Evidence at protein level HPA018485 Approved Validated Nucleus Liver cancer:1.88e-7 (unfavourable), Endometrial cancer:9.54e-5 (unfavourable), Pancreatic cancer:1.20e-4 (favourable) Expressed in all Expressed in all thyroid gland: 18.0 ZNF347 ZNF1111 ENSG00000197937 Zinc finger protein 347 19 53124072-53159075 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023448 Uncertain Approved Microtubules Mixed Expressed in all spleen: 14.4 ZNF354A EZNF, HKL1, KID-1, KID1, TCF17 ENSG00000169131 Zinc finger protein 354A 5 178711592-178730702 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052043 Approved Supported Nucleus
Nucleoli
Cytosol Renal cancer:3.45e-6 (unfavourable), Ovarian cancer:8.28e-4 (favourable) Expressed in all Expressed in all testis: 16.7 ZNF354B FLJ25008, KID2 ENSG00000178338 Zinc finger protein 354B 5 178859953-178888122 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA029056 Approved Approved Nucleoplasm Renal cancer:1.30e-5 (unfavourable), Head and neck cancer:9.52e-4 (favourable) Expressed in all Expressed in all placenta: 19.7 ZNF358 FLJ10390, ZFEND ENSG00000198816 Zinc finger protein 358 19 7515292-7521026 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030887, HPA063624 Approved Approved Nucleus Pancreatic cancer:2.50e-4 (favourable) Expressed in all Expressed in all ovary: 85.4 ZNF362 FLJ25476, lin-29, RN ENSG00000160094 Zinc finger protein 362 1 33256545-33300719 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059239 Uncertain Approved Nucleus
Nucleoli Expressed in all Expressed in all spleen: 22.6 ZNF37A KOX21, ZNF37 ENSG00000075407 Zinc finger protein 37A 10 38094336-38125544 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003172 Approved Approved Vesicles Renal cancer:2.31e-4 (unfavourable), Liver cancer:2.83e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 18.1 ZNF384 CAGH1A, CIZ, NMP4, NP, TNRC1 ENSG00000126746 Zinc finger protein 384 12 6666477-6689572 Cancer-related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004051 Supported Supported Nucleoplasm Expressed in all Expressed in all endometrium: 65.7 ZNF394 FLJ12298, ZKSCAN14, ZSCAN46 ENSG00000160908 Zinc finger protein 394 7 99486519-99500324 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051421, HPA054639 Uncertain Approved Nucleoplasm
Cytosol Urothelial cancer:1.09e-4 (favourable), Lung cancer:2.11e-4 (favourable), Breast cancer:3.56e-4 (favourable) Expressed in all Expressed in all bone marrow: 62.2 ZNF395 DKFZp434K1210, HDBP2, PBF, PRF-1 ENSG00000186918 Zinc finger protein 395 8 28345585-28402701 Predicted intracellular proteins Evidence at protein level HPA049382 Approved Nucleus
Cytosol Renal cancer:5.71e-5 (unfavourable), Liver cancer:1.66e-4 (unfavourable) Expressed in all Expressed in all ovary: 66.8 ZNF397 MGC13250, ZNF47, ZSCAN15 ENSG00000186812 Zinc finger protein 397 18 35241030-35267133 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026087 Uncertain Approved Nucleoli
Plasma membrane
Microtubules
Cytosol Pancreatic cancer:9.44e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 32.8 ZNF398 KIAA1339, P51, P71, ZER6 ENSG00000197024 Zinc finger protein 398 7 149126416-149182802 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA071533 Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all testis: 16.0 ZNF408 FLJ12827 ENSG00000175213 Zinc finger protein 408 11 46700818-46705912 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA017892 Uncertain Approved Microtubule organizing center
Cytosol Liver cancer:6.59e-5 (unfavourable) Expressed in all Expressed in all bone marrow: 8.3 ZNF410 APA-1, APA1 ENSG00000119725 Zinc finger protein 410 14 73886617-73932511 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002871 Approved Nuclear bodies Mixed Expressed in all testis: 80.7 ZNF414 MGC15716, Zfp414 ENSG00000133250 Zinc finger protein 414 19 8509678-8514164 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA053769 Approved Approved Nucleus
Cytosol Head and neck cancer:1.67e-6 (favourable), Endometrial cancer:4.17e-4 (favourable), Pancreatic cancer:4.59e-4 (favourable), Urothelial cancer:8.71e-4 (favourable) Expressed in all Expressed in all spleen: 12.6 ZNF417 MGC34079 ENSG00000173480 Zinc finger protein 417 19 57900296-57916610 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA042125, HPA043288, HPA056213 Uncertain Uncertain Nucleoplasm Urothelial cancer:3.48e-4 (favourable) Expressed in all Expressed in all epididymis: 59.5 ZNF428 C19orf37, MGC51082, Zfp428 ENSG00000131116 Zinc finger protein 428 19 43607219-43619874 Predicted intracellular proteins Evidence at protein level HPA042596, HPA048072 Uncertain Approved Nucleoli
Mitochondria Pancreatic cancer:3.60e-5 (favourable) Expressed in all Expressed in all cerebral cortex: 71.7 ZNF432 KIAA0798 ENSG00000256087 Zinc finger protein 432 19 52031379-52095738 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA052082, HPA060274, HPA065606 Uncertain Supported Nucleoplasm Urothelial cancer:4.11e-5 (favourable), Renal cancer:6.47e-4 (unfavourable) Expressed in all Expressed in all prostate: 20.7 ZNF433 FLJ40981 ENSG00000197647 Zinc finger protein 433 19 12014732-12035741 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA073724 Uncertain Approved Nuclear bodies Renal cancer:8.33e-15 (favourable) Expressed in all Expressed in all testis: 52.3 ZNF444 EZF2, FLJ11137, ZSCAN17 ENSG00000167685 Zinc finger protein 444 19 56132599-56160893 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA056895, HPA065203 Approved Supported Nucleus
Nucleoli Urothelial cancer:1.87e-4 (favourable), Renal cancer:2.61e-4 (unfavourable) Expressed in all Expressed in all seminal vesicle: 29.1 ZNF449 FLJ23614, ZSCAN19 ENSG00000173275 Zinc finger protein 449 X 135344796-135363152 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA018079 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 12.0 ZNF451 COASTER, dJ417I1.1, KIAA0576, KIAA1702 ENSG00000112200 Zinc finger protein 451 6 57086844-57170307 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028838 Approved Nucleus Expressed in all Expressed in all testis: 50.1 ZNF468 ENSG00000204604 Zinc finger protein 468 19 52838008-52857649 Predicted intracellular proteins, Transcription factors Evidence at transcript level Renal cancer:3.94e-7 (favourable), Breast cancer:6.87e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 20.3 ZNF493 FLJ36504 ENSG00000196268 Zinc finger protein 493 19 21397119-21427573 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Expressed in all thyroid gland: 34.6 ZNF496 MGC15548, ZKSCAN17, ZSCAN49 ENSG00000162714 Zinc finger protein 496 1 247297412-247331846 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055834 Uncertain Golgi apparatus Expressed in all Expressed in all fallopian tube: 23.9 ZNF506 DKFZp761G1812 ENSG00000081665 Zinc finger protein 506 19 19785839-19821751 Predicted intracellular proteins, Transcription factors Evidence at transcript level Expressed in all Expressed in all thyroid gland: 16.2 ZNF507 KIAA1084 ENSG00000168813 Zinc finger protein 507 19 32345594-32387667 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030964, HPA049728 Uncertain Supported Nucleoli
Cytosol Expressed in all Expressed in all testis: 34.8 ZNF510 KIAA0972 ENSG00000081386 Zinc finger protein 510 9 96755865-96778129 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049139 Uncertain Approved Nucleoplasm
Plasma membrane Renal cancer:5.94e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 12.2 ZNF511 MGC30006 ENSG00000198546 Zinc finger protein 511 10 133308475-133313162 Predicted membrane proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA035360 Uncertain Renal cancer:1.13e-4 (unfavourable) Expressed in all Expressed in all ovary: 11.4 ZNF512 KIAA1805 ENSG00000243943 Zinc finger protein 512 2 27582969-27623215 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA031430 Approved Validated Nucleus Lung cancer:5.08e-9 (favourable), Endometrial cancer:5.10e-4 (unfavourable), Pancreatic cancer:5.19e-4 (favourable), Breast cancer:9.79e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 44.9 ZNF512B GM632, MGC149845, MGC149846 ENSG00000196700 Zinc finger protein 512B 20 63956702-64048758 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA006688 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 17.7 ZNF513 FLJ32203, RP58 ENSG00000163795 Zinc finger protein 513 2 27377231-27380790 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA051493 Uncertain Liver cancer:6.21e-5 (unfavourable) Expressed in all Expressed in all testis: 25.9 ZNF514 FLJ14457 ENSG00000144026 Zinc finger protein 514 2 95147330-95165413 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA028974 Approved Approved Nucleoplasm
Nuclear bodies Expressed in all Expressed in all epididymis: 32.4 ZNF516 HsT287, KIAA0222 ENSG00000101493 Zinc finger protein 516 18 76358190-76495190 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA015792 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.21e-4 (favourable), Liver cancer:2.79e-4 (unfavourable), Breast cancer:7.09e-4 (favourable), Pancreatic cancer:7.96e-4 (favourable) Expressed in all Expressed in all endometrium: 54.1 ZNF524 MGC23143 ENSG00000171443 Zinc finger protein 524 19 55600022-55603138 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050981 Uncertain Approved Nucleus Urothelial cancer:4.98e-8 (favourable) Expressed in all Expressed in all spleen: 16.0 ZNF528 KIAA1827 ENSG00000167555 Zinc finger protein 528 19 52397849-52418412 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA065435 Approved Nuclear speckles
Cytosol Expressed in all Expressed in all thyroid gland: 31.1 ZNF544 AF020591 ENSG00000198131 Zinc finger protein 544 19 58228594-58277495 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA002732 Approved Approved Nucleoplasm Liver cancer:1.04e-5 (unfavourable), Melanoma:3.65e-5 (unfavourable) Expressed in all Expressed in all testis: 49.3 ZNF548 FLJ32932 ENSG00000188785 Zinc finger protein 548 19 57389850-57402992 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA066042 Uncertain Approved Nucleus Breast cancer:7.85e-4 (favourable) Expressed in all Expressed in all lymph node: 33.1 ZNF559 MGC13105 ENSG00000188321 Zinc finger protein 559 19 9323772-9351162 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059632, HPA065485 Approved Supported Nucleoplasm
Cytosol Ovarian cancer:6.99e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 39.9 ZNF561 MGC45408 ENSG00000171469 Zinc finger protein 561 19 9604680-9621399 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055332, HPA062397 Uncertain Approved Nucleoplasm Renal cancer:1.16e-4 (favourable), Ovarian cancer:1.31e-4 (favourable) Expressed in all Expressed in all smooth muscle: 37.6 ZNF562 FLJ20079 ENSG00000171466 Zinc finger protein 562 19 9641808-9675086 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA055332, HPA062397 Uncertain Approved Nucleoplasm Head and neck cancer:4.17e-4 (favourable) Expressed in all Expressed in all esophagus: 19.1 ZNF574 FLJ22059 ENSG00000105732 Zinc finger protein 574 19 42068477-42081565 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023196, HPA057274 Approved Supported Nucleoplasm Expressed in all Expressed in all testis: 40.2 ZNF576 MGC2508 ENSG00000124444 Zinc finger protein 576 19 43596392-43601157 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA050064 Uncertain Approved Nucleoplasm
Golgi apparatus Liver cancer:1.29e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex,prostate: 14.7 ZNF577 MGC4400 ENSG00000161551 Zinc finger protein 577 19 51855802-51890950 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041499, HPA046761 Uncertain Supported Nucleus
Nucleoli Urothelial cancer:2.03e-4 (favourable) Mixed Expressed in all testis: 42.1 ZNF579 FLJ35453 ENSG00000218891 Zinc finger protein 579 19 55576770-55580845 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062812 Approved Approved Nucleus Renal cancer:1.00e-5 (unfavourable) Expressed in all Expressed in all gallbladder: 13.0 ZNF580 ENSG00000213015 Zinc finger protein 580 19 55635016-55643469 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054058 Approved Approved Nucleus Renal cancer:5.79e-6 (unfavourable), Pancreatic cancer:2.36e-5 (favourable), Liver cancer:5.63e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.6 ZNF581 FLJ22550, HSPC189 ENSG00000171425 Zinc finger protein 581 19 55635459-55645622 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059657 Uncertain Liver cancer:5.74e-5 (unfavourable) Expressed in all Expressed in all ovary: 21.6 ZNF585A FLJ23765 ENSG00000196967 Zinc finger protein 585A 19 37106734-37172741 Predicted intracellular proteins, Transcription factors Evidence at transcript level Mixed Expressed in all thyroid gland: 17.7 ZNF586 FLJ20070 ENSG00000083828 Zinc finger protein 586 19 57769655-57819939 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030306, HPA060782 Approved Approved Nucleoli fibrillar center
Vesicles Breast cancer:9.83e-5 (favourable), Urothelial cancer:5.36e-4 (favourable) Expressed in all Expressed in all bone marrow: 16.3 ZNF592 CAMOS, KIAA0211, SCAR5 ENSG00000166716 Zinc finger protein 592 15 84748635-84806432 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020332, HPA021600 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 16.5 ZNF593 ZT86 ENSG00000142684 Zinc finger protein 593 1 26169871-26172060 Predicted intracellular proteins Evidence at protein level HPA054363, HPA059387 Supported Validated Nucleus
Nucleoli Expressed in all Expressed in all appendix: 4.5 ZNF595 FLJ31740 ENSG00000272602 Zinc finger protein 595 4 53285-88211 Predicted intracellular proteins Evidence at protein level Expressed in all Expressed in all placenta: 87.4 ZNF606 FLJ14260, KIAA1852, ZNF328 ENSG00000166704 Zinc finger protein 606 19 57977053-58003349 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA041712, HPA043584 Uncertain Supported Nucleoplasm Urothelial cancer:4.75e-6 (favourable) Expressed in all Expressed in all parathyroid gland: 18.9 ZNF609 KIAA0295 ENSG00000180357 Zinc finger protein 609 15 64460742-64686068 Predicted intracellular proteins Evidence at protein level HPA040742, HPA040832 Approved Validated Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 40.8 ZNF616 MGC45556 ENSG00000204611 Zinc finger protein 616 19 52113091-52139922 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA062639, HPA071539 Approved Approved Centrosome Expressed in all Expressed in all adrenal gland: 17.4 ZNF621 FLJ45246 ENSG00000172888 Zinc finger protein 621 3 40524878-40574685 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA065518, HPA071440 Supported Nuclear speckles Expressed in all Expressed in all parathyroid gland: 22.9 ZNF622 MGC17552, MGC2485, ZPR9 ENSG00000173545 Zinc finger protein 622 5 16451519-16465792 Predicted intracellular proteins Evidence at protein level HPA036514, HPA036515 Uncertain Validated Nucleus
Nucleoli
Golgi apparatus
Cytosol Expressed in all Expressed in all cerebral cortex: 26.6 ZNF626 ENSG00000188171 Zinc finger protein 626 19 20620061-20661596 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA045631 Uncertain Approved Nucleoplasm
Nuclear membrane
Vesicles Mixed Expressed in all parathyroid gland: 52.0 ZNF627 FLJ90365 ENSG00000198551 Zinc finger protein 627 19 11559374-11619135 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049770, HPA073463 Uncertain Approved Nucleus
Nucleoli Renal cancer:6.93e-7 (favourable), Head and neck cancer:8.12e-4 (favourable) Expressed in all Expressed in all thyroid gland: 20.6 ZNF629 KIAA0326, ZNF65 ENSG00000102870 Zinc finger protein 629 16 30778449-30787202 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA019550, HPA056051 Uncertain Supported Nucleus
Golgi apparatus Renal cancer:4.57e-10 (favourable) Expressed in all Expressed in all parathyroid gland: 27.4 ZNF638 MGC26130, NP220, ZFML, Zfp638 ENSG00000075292 Zinc finger protein 638 2 71276561-71435069 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA036784, HPA057395 Supported Validated Nucleoplasm
Vesicles Urothelial cancer:8.73e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 57.8 ZNF639 ANC-2H01, ZASC1 ENSG00000121864 Zinc finger protein 639 3 179322991-179338583 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049023, HPA052163 Uncertain Supported Nucleoplasm Glioma:7.36e-5 (favourable), Liver cancer:2.13e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 68.7 ZNF641 FLJ31295 ENSG00000167528 Zinc finger protein 641 12 48337180-48351414 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035189 Uncertain Supported Nucleoplasm Pancreatic cancer:8.30e-5 (favourable), Ovarian cancer:3.91e-4 (favourable) Expressed in all Expressed in all adrenal gland: 29.0 ZNF644 BM-005, KIAA1221, MGC60165, MGC70410 ENSG00000122482 Zinc finger protein 644 1 90915298-91022272 Disease related genes, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA057795 Uncertain Uncertain Vesicles Colorectal cancer:4.27e-4 (favourable), Endometrial cancer:8.39e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 31.0 ZNF649 FLJ12644 ENSG00000198093 Zinc finger protein 649 19 51889224-51905040 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA026541 Uncertain Renal cancer:4.60e-5 (favourable), Melanoma:7.44e-4 (unfavourable) Expressed in all Expressed in all prostate: 34.0 ZNF655 VIK, VIK-1 ENSG00000197343 Zinc finger protein 655 7 99558406-99576453 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA029534, HPA050750 Uncertain Supported Nucleoplasm
Plasma membrane Breast cancer:7.12e-4 (favourable), Melanoma:7.24e-4 (unfavourable) Expressed in all Expressed in all lymph node: 21.5 ZNF664 DKFZp761B128, ZFOC1, ZNF176 ENSG00000179195 Zinc finger protein 664 12 123971845-124015439 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA047846 Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 231.9 ZNF672 FLJ22301 ENSG00000171161 Zinc finger protein 672 1 248838210-248849517 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA055779, HPA062506 Approved Validated Nucleoplasm Urothelial cancer:1.79e-5 (favourable), Pancreatic cancer:7.51e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 24.3 ZNF675 TBZF, TIZ ENSG00000197372 Zinc finger protein 675 19 23525631-23687220 Predicted intracellular proteins, Transcription factors Evidence at protein level Mixed Expressed in all testis: 25.0 ZNF677 MGC48625 ENSG00000197928 Zinc finger protein 677 19 53235381-53254898 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023106, HPA024796 Approved Approved Nucleus
Centrosome Mixed Expressed in all testis: 71.0 ZNF680 FLJ90430 ENSG00000173041 Zinc finger protein 680 7 64519884-64563106 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA003173 Approved Nucleus Expressed in all Expressed in all thyroid gland: 42.3 ZNF687 KIAA1441 ENSG00000143373 Zinc finger protein 687 1 151281618-151292180 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021193, HPA023948 Approved Validated Nucleoplasm Expressed in all Expressed in all parathyroid gland: 25.9 ZNF688 ENSG00000229809 Zinc finger protein 688 16 30569346-30572734 Predicted intracellular proteins Evidence at transcript level HPA048922 Uncertain Approved Nucleoplasm
Plasma membrane
Cell Junctions Endometrial cancer:4.58e-5 (favourable), Lung cancer:3.24e-4 (favourable), Breast cancer:5.90e-4 (favourable), Pancreatic cancer:6.61e-4 (favourable), Cervical cancer:7.74e-4 (favourable) Expressed in all Expressed in all testis: 23.9 ZNF689 FLJ90415 ENSG00000156853 Zinc finger protein 689 16 30602558-30624012 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054095, HPA055385 Approved Approved Nucleus
Nucleoli fibrillar center Pancreatic cancer:9.89e-4 (favourable) Expressed in all Expressed in all testis: 35.3 ZNF691 Zfp691 ENSG00000164011 Zinc finger protein 691 1 42846573-42852477 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA062527 Approved Approved Nucleus
Nucleoli
Vesicles Liver cancer:7.33e-6 (unfavourable), Pancreatic cancer:6.25e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 21.4 ZNF692 AREBP, FLJ20531, Zfp692 ENSG00000171163 Zinc finger protein 692 1 248850006-248859144 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059337, HPA062792 Uncertain Validated Nucleus
Nucleoli Renal cancer:7.72e-9 (unfavourable), Urothelial cancer:8.35e-5 (favourable), Pancreatic cancer:4.09e-4 (favourable) Expressed in all Expressed in all testis: 26.8 ZNF7 HF.16, KOX4 ENSG00000147789 Zinc finger protein 7 8 144827464-144847509 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030296, HPA059090 Uncertain Approved Mitochondria Renal cancer:8.46e-8 (unfavourable) Expressed in all Expressed in all testis: 31.4 ZNF700 DKFZp434I1610 ENSG00000196757 Zinc finger protein 700 19 11925068-11950773 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA047845 Uncertain Uncertain Nucleus Renal cancer:2.01e-5 (unfavourable), Urothelial cancer:2.53e-5 (favourable), Head and neck cancer:1.27e-4 (favourable), Prostate cancer:1.75e-4 (unfavourable), Melanoma:2.58e-4 (unfavourable) Expressed in all Expressed in all skin: 19.1 ZNF706 HSPC038 ENSG00000120963 Zinc finger protein 706 8 101177878-101206193 Predicted intracellular proteins Evidence at protein level HPA042793 Approved Plasma membrane Renal cancer:5.90e-11 (unfavourable), Endometrial cancer:3.12e-5 (unfavourable) Expressed in all Expressed in all skin: 159.7 ZNF710 DKFZp547K1113, FLJ00306, FLJ37393 ENSG00000140548 Zinc finger protein 710 15 90001392-90082206 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030226, HPA030227, HPA030228 Supported Approved Nucleoplasm
Mitochondria Expressed in all Expressed in all appendix: 20.9 ZNF717 X17, ZNF838 ENSG00000227124 Zinc finger protein 717 3 75709643-75785583 Predicted intracellular proteins Evidence at transcript level HPA044549 Uncertain Approved Nucleoplasm
Nuclear bodies
Plasma membrane Mixed Expressed in all epididymis: 29.1 ZNF720 ENSG00000197302 Zinc finger protein 720 16 31713229-31794869 Predicted intracellular proteins Evidence at transcript level HPA041570 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 15.4 ZNF721 KIAA1982 ENSG00000182903 Zinc finger protein 721 4 425815-499156 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA065313 Approved Microtubule organizing center
Cytosol Urothelial cancer:2.76e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 30.9 ZNF740 Zfp740 ENSG00000139651 Zinc finger protein 740 12 53180700-53195141 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA035691 Approved Approved Nucleus Melanoma:4.55e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 14.2 ZNF746 FLJ31413, PARIS ENSG00000181220 Zinc finger protein 746 7 149472794-149497817 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA020272 Approved Renal cancer:7.47e-6 (unfavourable), Liver cancer:2.32e-5 (unfavourable), Pancreatic cancer:4.22e-4 (favourable) Expressed in all Expressed in all testis: 23.2 ZNF75A FLJ31529 ENSG00000162086 Zinc finger protein 75a 16 3305406-3318852 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA001665 Uncertain Approved Nucleoplasm
Nucleoli fibrillar center Expressed in all Expressed in all parathyroid gland: 45.5 ZNF75D D8C6, ZKSCAN24, ZNF75, ZNF82, ZSCAN28 ENSG00000186376 Zinc finger protein 75D X 135248920-135344087 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA004705 Supported Approved Nucleoplasm
Golgi apparatus Urothelial cancer:7.42e-5 (favourable), Renal cancer:1.31e-4 (favourable) Expressed in all Expressed in all prostate: 16.1 ZNF76 D6S229E, Zfp523, ZNF523 ENSG00000065029 Zinc finger protein 76 6 35258909-35295985 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030090, HPA030091 Approved Approved Nucleoplasm
Cytosol Ovarian cancer:1.18e-4 (favourable), Pancreatic cancer:5.09e-4 (favourable) Expressed in all Expressed in all thyroid gland: 34.5 ZNF761 FLJ16231, FLJ35333, KIAA2033 ENSG00000160336 Zinc finger protein 761 19 53431993-53458261 Predicted intracellular proteins Evidence at transcript level Liver cancer:2.04e-4 (unfavourable) Expressed in all Expressed in all prostate: 94.4 ZNF766 ENSG00000196214 Zinc finger protein 766 19 52269571-52296046 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA044882, HPA063496 Uncertain Supported Centrosome Expressed in all Expressed in all testis: 43.5 ZNF768 FLJ23436 ENSG00000169957 Zinc finger protein 768 16 30524001-30526821 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024630, HPA066512 Supported Approved Nucleus
Vesicles Renal cancer:9.30e-6 (favourable), Urothelial cancer:6.46e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 55.0 ZNF770 FLJ20582, PRO1914 ENSG00000198146 Zinc finger protein 770 15 34978341-34988287 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA024518 Approved Expressed in all Expressed in all thyroid gland: 73.3 ZNF777 KIAA1285 ENSG00000196453 Zinc finger protein 777 7 149431363-149461123 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA003252 Approved Approved Nucleus Expressed in all Expressed in all cerebral cortex: 10.4 ZNF784 MGC75238 ENSG00000179922 Zinc finger protein 784 19 55620742-55624601 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA059676 Uncertain Approved Nucleus Urothelial cancer:1.02e-4 (favourable) Expressed in all Expressed in all skeletal muscle: 14.7 ZNF785 FLJ32130 ENSG00000197162 Zinc finger protein 785 16 30573740-30585771 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA030510 Approved Nucleoplasm
Plasma membrane Pancreatic cancer:2.03e-5 (favourable), Lung cancer:8.99e-4 (favourable) Expressed in all Expressed in all endometrium: 11.8 ZNF787 ENSG00000142409 Zinc finger protein 787 19 56087366-56121280 Predicted intracellular proteins Evidence at protein level HPA035140 Supported Approved Nucleus
Nucleoli
Mitochondria Expressed in all Expressed in all spleen: 19.7 ZNF791 FLJ90396 ENSG00000173875 Zinc finger protein 791 19 12610918-12633840 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA021537 Uncertain Approved Nucleus Urothelial cancer:1.39e-5 (favourable), Lung cancer:9.07e-4 (favourable) Expressed in all Expressed in all thyroid gland: 25.0 ZNF800 ENSG00000048405 Zinc finger protein 800 7 127346790-127431924 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA023090, HPA052194 Approved Supported Nucleoli
Cytosol Expressed in all Expressed in all bone marrow: 48.0 ZNF83 FLJ11015, HPF1, ZNF816B ENSG00000167766 Zinc finger protein 83 19 52594060-52690496 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA025970 Approved Approved Nucleoplasm Urothelial cancer:6.92e-6 (favourable), Renal cancer:3.13e-5 (unfavourable), Head and neck cancer:3.83e-4 (favourable), Ovarian cancer:9.06e-4 (favourable), Melanoma:9.20e-4 (unfavourable) Expressed in all Expressed in all epididymis: 110.8 ZNF830 CCDC16, MGC20398, OMCG1 ENSG00000198783 Zinc finger protein 830 17 34961530-34963775 Predicted intracellular proteins Evidence at protein level HPA024754, HPA027211 Supported Validated Nucleoplasm Prostate cancer:2.01e-4 (unfavourable) Expressed in all Expressed in all spleen: 16.9 ZNF839 C14orf131 ENSG00000022976 Zinc finger protein 839 14 102317377-102342702 Predicted intracellular proteins Evidence at protein level HPA020434 Uncertain Approved Nucleoplasm
Plasma membrane Pancreatic cancer:4.57e-4 (favourable), Renal cancer:5.00e-4 (favourable) Expressed in all Expressed in all testis: 36.9 ZNF84 HPF2 ENSG00000198040 Zinc finger protein 84 12 133037292-133063304 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA028860 Approved Supported Nucleoplasm Liver cancer:1.59e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 32.9 ZNF862 ENSG00000106479 Zinc finger protein 862 7 149838367-149867479 Predicted intracellular proteins Evidence at protein level HPA024154 Uncertain Approved Mitochondria Urothelial cancer:8.66e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 23.5 ZNF880 ENSG00000221923 Zinc finger protein 880 19 52369917-52385795 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA077316 Approved Intermediate filaments Renal cancer:4.33e-8 (favourable) Expressed in all Expressed in all thyroid gland: 31.2 ZNFX1 FLJ11277, KIAA1404 ENSG00000124201 Zinc finger, NFX1-type containing 1 20 49237946-49278426 Plasma proteins, Predicted intracellular proteins, Transcription factors Evidence at protein level HPA046629 Approved Approved Mitochondria Expressed in all Expressed in all lung: 27.1 ZNHIT1 CG1I, H_DJ0747G18.14, ZNFN4A1 ENSG00000106400 Zinc finger, HIT-type containing 1 7 101217668-101224190 Predicted intracellular proteins Evidence at protein level HPA019043 Uncertain Approved Nucleoplasm Expressed in all Expressed in all liver: 50.5 ZNHIT3 TRIP3 ENSG00000273611 Zinc finger, HIT-type containing 3 17 36486629-36499310 Predicted intracellular proteins Evidence at protein level HPA060019 Approved Mitochondria Expressed in all Expressed in all testis: 42.7 ZNHIT6 BCD1, C1orf181, FLJ20729, NY-BR-75 ENSG00000117174 Zinc finger, HIT-type containing 6 1 85649423-85708433 Predicted intracellular proteins Evidence at protein level HPA018132 Uncertain Approved Nuclear speckles
Vesicles Liver cancer:6.08e-6 (unfavourable) Expressed in all Expressed in all cervix, uterine: 21.1 ZNRF1 DKFZp434E229, FLJ14846, nin283 ENSG00000186187 Zinc and ring finger 1, E3 ubiquitin protein ligase 16 74999030-75110994 Predicted intracellular proteins Evidence at protein level HPA027470 Approved Cervical cancer:9.90e-4 (favourable) Expressed in all Expressed in all testis: 34.2 ZNRF2 RNF202 ENSG00000180233 Zinc and ring finger 2, E3 ubiquitin protein ligase 7 30284307-30367692 Predicted intracellular proteins Evidence at protein level Renal cancer:2.29e-4 (favourable), Endometrial cancer:7.68e-4 (unfavourable), Thyroid cancer:8.71e-4 (favourable) Expressed in all Expressed in all testis: 39.5 ZPR1 ZNF259 ENSG00000109917 ZPR1 zinc finger 11 116773799-116788050 Predicted intracellular proteins Evidence at protein level CAB022596, HPA030979 Uncertain Approved Vesicles Liver cancer:5.87e-6 (unfavourable), Head and neck cancer:8.01e-4 (unfavourable) Expressed in all Expressed in all testis: 43.6 ZRANB1 TRABID ENSG00000019995 Zinc finger, RAN-binding domain containing 1 10 124942123-124988189 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029239, HPA029240, HPA029241 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 34.5 ZRANB2 ZIS, ZIS1, ZIS2, ZNF265 ENSG00000132485 Zinc finger, RAN-binding domain containing 2 1 71063291-71081297 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA053960, HPA061949, HPA063298 Supported Validated Nucleus Renal cancer:1.57e-8 (unfavourable), Liver cancer:7.29e-5 (unfavourable), Prostate cancer:5.70e-4 (unfavourable) Expressed in all Expressed in all endometrium: 117.1 ZRSR2 U2AF1-RS2, U2AF1L2, URP, ZC3H22 ENSG00000169249 Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 X 15790472-15823260 Cancer-related genes, Predicted intracellular proteins Evidence at protein level Renal cancer:4.87e-5 (unfavourable), Endometrial cancer:8.50e-5 (favourable), Urothelial cancer:2.97e-4 (favourable), Breast cancer:7.96e-4 (favourable) Expressed in all Expressed in all spleen: 34.8 ZSCAN18 FLJ12895, ZNF447 ENSG00000121413 Zinc finger and SCAN domain containing 18 19 58083838-58118427 Predicted intracellular proteins Evidence at protein level HPA024318 Supported Approved Nucleoplasm Renal cancer:3.95e-7 (favourable) Expressed in all Expressed in all cerebral cortex: 78.9 ZSCAN2 FLJ20595, ZFP29, ZNF854 ENSG00000176371 Zinc finger and SCAN domain containing 2 15 84600986-84627796 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007296, HPA024331 Supported Approved Nucleoplasm
Cytosol Urothelial cancer:4.16e-5 (favourable), Pancreatic cancer:3.52e-4 (favourable), Renal cancer:7.46e-4 (favourable) Expressed in all Expressed in all testis: 14.0 ZSCAN21 DKFZp434L134, NY-REN-21, Zipro1, ZNF38 ENSG00000166529 Zinc finger and SCAN domain containing 21 7 100049774-100065038 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA016948, HPA023591 Uncertain Approved Endoplasmic reticulum Thyroid cancer:4.71e-4 (unfavourable) Expressed in all Expressed in all testis: 20.5 ZSCAN26 SRE-ZBP, ZNF187 ENSG00000197062 Zinc finger and SCAN domain containing 26 6 28267010-28278224 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA027521 Validated Nucleus
Nucleoli Renal cancer:6.79e-5 (unfavourable), Liver cancer:7.81e-5 (unfavourable), Urothelial cancer:1.68e-4 (favourable) Expressed in all Expressed in all ovary: 40.3 ZSCAN29 FLJ35867, Zfp690, ZNF690 ENSG00000140265 Zinc finger and SCAN domain containing 29 15 43358172-43371025 Predicted intracellular proteins, Predicted secreted proteins, Transcription factors Evidence at protein level HPA007241, HPA011109 Approved Approved Nucleoplasm
Plasma membrane
Actin filaments Expressed in all Expressed in all testis: 27.5 ZSCAN30 ZNF397OS, ZNF917 ENSG00000186814 Zinc finger and SCAN domain containing 30 18 35251058-35290245 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007289 Approved Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 27.1 ZSCAN31 ZNF310P, ZNF323 ENSG00000235109 Zinc finger and SCAN domain containing 31 6 28324693-28356271 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA007124 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.19e-5 (favourable) Expressed in all Expressed in all testis: 40.7 ZSCAN32 FLJ20417, ZNF434 ENSG00000140987 Zinc finger and SCAN domain containing 32 16 3382081-3401065 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA005758 Uncertain Approved Nucleoplasm Mixed Expressed in all parathyroid gland: 14.4 ZSCAN9 PRD51, ZNF193 ENSG00000137185 Zinc finger and SCAN domain containing 9 6 28224886-28233482 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA054512, HPA059951 Uncertain Approved Nucleoplasm Renal cancer:1.21e-6 (unfavourable), Urothelial cancer:1.16e-5 (favourable), Liver cancer:3.49e-4 (unfavourable) Expressed in all Expressed in all testis: 34.7 ZSWIM1 C20orf162, dJ337O18.5 ENSG00000168612 Zinc finger, SWIM-type containing 1 20 45881227-45885266 Predicted intracellular proteins Evidence at protein level HPA041147, HPA046751 Uncertain Approved Plasma membrane
Cytosol Pancreatic cancer:1.77e-4 (favourable), Liver cancer:5.47e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 10.6 ZSWIM8 4832404P21Rik, KIAA0913 ENSG00000214655 Zinc finger, SWIM-type containing 8 10 73785582-73801797 Predicted intracellular proteins Evidence at protein level HPA041244 Approved Approved Plasma membrane
Cytosol Head and neck cancer:5.61e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 62.8 ZW10 KNTC1AP ENSG00000086827 Zw10 kinetochore protein 11 113733187-113773811 Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB011565, HPA051253, HPA055410 Supported Supported Cytosol Colorectal cancer:2.70e-4 (favourable), Liver cancer:8.57e-4 (unfavourable) Expressed in all Expressed in all testis: 23.3 ZXDB ZNF905 ENSG00000198455 Zinc finger, X-linked, duplicated B X 57591652-57597545 Predicted intracellular proteins, Transcription factors Evidence at transcript level HPA043789 Approved Approved Nucleoplasm Expressed in all Expressed in all parathyroid gland: 9.9 ZXDC FLJ13861, MGC11349 ENSG00000070476 ZXD family zinc finger C 3 126437601-126475919 Predicted intracellular proteins, Transcription factors Evidence at protein level HPA049593 Supported Nucleoli
Vesicles Liver cancer:2.27e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 25.5 ZYG11B FLJ13456, ZYG11 ENSG00000162378 Zyg-11 family member B, cell cycle regulator 1 52726467-52827342 Predicted intracellular proteins Evidence at protein level HPA028156 Uncertain Approved Golgi apparatus
Intermediate filaments Renal cancer:9.80e-7 (favourable), Colorectal cancer:5.42e-6 (favourable) Expressed in all Expressed in all cerebral cortex: 29.0 ZYX ENSG00000159840 Zyxin 7 143381080-143391111 Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004835, CAB009321, HPA073497, CAB075747 Approved Supported Focal adhesion sites Renal cancer:7.92e-5 (unfavourable) Expressed in all Expressed in all parathyroid gland: 388.9 ZZEF1 FLJ10821, KIAA0399, ZZZ4 ENSG00000074755 Zinc finger, ZZ-type with EF-hand domain 1 17 4004445-4143020 Predicted membrane proteins Evidence at protein level HPA031778, HPA031790 Uncertain Approved Nucleoplasm
Mitochondria Head and neck cancer:1.02e-4 (favourable), Pancreatic cancer:6.08e-4 (favourable) Expressed in all Expressed in all small intestine: 26.3 ZZZ3 ATAC1, DKFZP564I052 ENSG00000036549 Zinc finger, ZZ-type containing 3 1 77562416-77683419 Predicted intracellular proteins Evidence at protein level HPA053663, HPA054913, HPA066197 Uncertain Approved Nucleus
Nucleoli Liver cancer:6.96e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 32.7