Moderate cytoplasmic and nuclear positivity was observed in several hepatocellular carcinomas while several renal cancers showed moderate cytoplasmic staining. Remaining malignancies were generally negative.
Most malignancies were negative. A few cases of skin cancers, malignant gliomas and melanomas displayed moderate cytoplasmic positivity.
Tenascin R (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of sodium channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013]