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Strong cytoplasmic and membranous staining of luminal membranes in gastrointestinal tract and in axonal projections in cns. Weak to moderate cytoplasmic staining in most other tissues and virtually no staining in leucocytes, pancreas and most mesenchymal cells. A membranous positivity was found in renal tubules and bowman´s capsule of the kidney.
HPA024566
A majority of normal tissues generally showed moderate cytoplasmic staining. Epididymis, gall bladder and renal tubules showed strong cytoplasmic positivity while purkinje cells displayed strong nuclear and cytoplasmic staining. Breast, cells in CNS, lymphoid tissues and most squamous epithelia were negative or weakly stained.