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MGARP

GENERAL INFORMATION

Gene name

 MGARP

Gene description

 Mitochondria-localized glutamic acid-rich protein

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (adrenal gland)
GTEx:Tissue enriched (adrenal gland)
FANTOM5:Tissue enhanced (pituitary gland, retina)

Protein evidence

 Evidence at protein level

Protein expression

 Selective expression in adrenal gland, testis, ovary and cerebellum.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA015994
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (adrenal gland)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (adrenal gland)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (pituitary gland, retina)

GENE INFORMATION

Gene name

 MGARP (HGNC Symbol)

Synonyms

 C4orf49, CESP-1, HUMMR, OSAP

Description

 Mitochondria-localized glutamic acid-rich protein (HGNC Symbol)

Entrez gene summary

Chromosome

 4

Cytoband

 q31.1

Chromosome location (bp)

 139266163 - 139280338

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000137463 (version 83.38)

Entrez gene

 84709

UniProt

 Q8TDB4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TDB4

Antibodypedia

 MGARP antibodies

PROTEIN BROWSER
MGARP-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MGARP-001
ENSP00000381928
ENST00000398955
Q8TDB4 [Direct mapping]
Protein MGARP
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0006626 [protein targeting to mitochondrion]
GO:0008089 [anterograde axon cargo transport]
GO:0008090 [retrograde axon cargo transport]
GO:0010821 [regulation of mitochondrion organization]
GO:0010822 [positive regulation of mitochondrion organization]
GO:0019896 [axon transport of mitochondrion]
GO:0031307 [integral component of mitochondrial outer membrane]
GO:0071383 [cellular response to steroid hormone stimulus]
GO:0071456 [cellular response to hypoxia]
GO:0097211 [cellular response to gonadotropin-releasing hormone]
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 240 aa
25.4 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.