Expression of CFAP157 in cancer - Summary - The Human Protein Atlas

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CFAP157

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TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CFAP157
Gene description	Cilia and flagella associated protein 157
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enriched (fallopian tube)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective expression in cilia in fallopian tube, respiratory tract and endometrium.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 2 antibodies. HPA021474 , HPA021786
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA021474	HPA021786

GENE INFORMATION
Gene name	CFAP157 (HGNC Symbol)
Synonyms	C9orf117
Description	Cilia and flagella associated protein 157 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q34.11
Chromosome location (bp)	127706989 - 127716002
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000160401 (version 83.38)
Entrez gene	286207
UniProt	Q5JU67 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5JU67
Antibodypedia	CFAP157 antibodies

PROTEIN BROWSER

CFAP157-001	CFAP157-004	CFAP157-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CFAP157-001 ENSP00000362392 ENST00000373295	Q5JU67 [Direct mapping] Uncharacterized protein C9orf117 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all		520 aa 60.5 kDa	No	0
CFAP157-004 ENSP00000485445 ENST00000461104	A0A096LP78 [Direct mapping] Uncharacterized protein C9orf117 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		137 aa 15.2 kDa	No	0
CFAP157-201 ENSP00000478313 ENST00000614677	Q5JU67 [Direct mapping] Uncharacterized protein C9orf117 Show all	Predicted intracellular proteins Show all		425 aa 49.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.