Expression of CDC20B in cancer - Summary - The Human Protein Atlas

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CDC20B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CDC20B
Gene description	Cell division cycle 20B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (endometrial cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (endometrium, fallopian tube, kidney, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

RNA-based expert annotation gave inconclusive results.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 1 antibody. HPA053900
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA053900

GENE INFORMATION
Gene name	CDC20B (HGNC Symbol)
Synonyms	FLJ37927
Description	Cell division cycle 20B (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q11.2
Chromosome location (bp)	55112995 - 55173175
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164287 (version 83.38)
Entrez gene	166979
UniProt	Q86Y33 (UniProt - Evidence at protein level)
neXtProt	NX_Q86Y33
Antibodypedia	CDC20B antibodies

PROTEIN BROWSER

CDC20B-001	CDC20B-003	CDC20B-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDC20B-001 ENSP00000296733 ENST00000296733	Q86Y33 [Direct mapping] Cell division cycle protein 20 homolog B Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	515 aa 56.9 kDa	No	0
CDC20B-003 ENSP00000315720 ENST00000322374	Q86Y33 [Direct mapping] Cell division cycle protein 20 homolog B Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	477 aa 52.9 kDa	No	0
CDC20B-004 ENSP00000370781 ENST00000381375	Q86Y33 [Direct mapping] Cell division cycle protein 20 homolog B Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	519 aa 57.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.