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Most squamous cell carcinomas and cases of urothelial cancers were moderately stained. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
RXFP1 (HGNC Symbol)
Synonyms
LGR7, RXFPR1
Description
Relaxin/insulin-like family peptide receptor 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]