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Most malignant tissues showed weak to moderate cytoplasmic positivity. Malignant melanomas, pancreatic, renal and urothelial cancers exhibited moderate to strong cytoplasmic staining and occasional membranous positivity. Thyroid cancers exhibited staining similar to the previously mentioned combined with nuclear positivity in some cases.
GENE INFORMATION
Gene name
IGSF22 (HGNC Symbol)
Synonyms
FLJ37794, IGFN2
Description
Immunoglobulin superfamily, member 22 (HGNC Symbol)