Expression of C6orf222 in cancer - Summary - The Human Protein Atlas

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C6orf222

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C6orf222
Gene description	Chromosome 6 open reading frame 222
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (colorectal cancer, pancreatic cancer, stomach cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enhanced (duodenum, small intestine)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA038407 , HPA058189
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (colorectal cancer, pancreatic cancer, stomach cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038407	HPA058189

GENE INFORMATION
Gene name	C6orf222 (HGNC Symbol)
Synonyms	DKFZp779B1540
Description	Chromosome 6 open reading frame 222 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.31
Chromosome location (bp)	36315757 - 36336885
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000189325 (version 83.38)
Entrez gene	389384
UniProt	P0C671 (UniProt - Evidence at protein level)
neXtProt	NX_P0C671
Antibodypedia	C6orf222 antibodies

PROTEIN BROWSER

C6orf222-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C6orf222-001 ENSP00000418983 ENST00000437635	P0C671 [Direct mapping] Uncharacterized protein C6orf222 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all		652 aa 71.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.