Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific ADGB C6orf103, CAPN16, dJ408K24.1, FLJ23121 ENSG00000118492 Androglobin 6 146598965-146815462 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036340, HPA036341 Supported Uncertain Nucleoplasm
Mitochondria Not detected Group enriched 24 fallopian tube: 14.6;testis: 58.0 lung: 1.4 ATG4A APG4A, AUTL2 ENSG00000101844 Autophagy related 4A, cysteine peptidase X 108091668-108154671 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036374, HPA064759 Uncertain Approved Actin filaments
Microtubules Breast cancer:1.36e-5 (unfavourable) Expressed in all Expressed in all thyroid gland: 17.7 ATG4B APG4B, AUTL1, DKFZp586D1822, KIAA0943 ENSG00000168397 Autophagy related 4B, cysteine peptidase 2 241637213-241673857 Enzymes, Predicted intracellular proteins Evidence at protein level CAB037195, HPA069803 Approved Approved Nucleoplasm
Cytosol Renal cancer:2.79e-4 (unfavourable), Colorectal cancer:6.85e-4 (unfavourable), Urothelial cancer:9.64e-4 (favourable) Expressed in all Expressed in all testis: 43.9 ATG4C APG4C, AUTL1, AUTL3, FLJ14867 ENSG00000125703 Autophagy related 4C, cysteine peptidase 1 62784135-62865513 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007049 Approved Approved Nucleoplasm
Cytosol Colorectal cancer:9.83e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 23.6 ATG4D APG4-D, APG4D, AUTL4 ENSG00000130734 Autophagy related 4D, cysteine peptidase 19 10543895-10553418 Enzymes, Predicted intracellular proteins Evidence at protein level HPA067683 Approved Renal cancer:2.39e-7 (favourable), Cervical cancer:3.18e-5 (favourable), Stomach cancer:5.03e-4 (favourable), Pancreatic cancer:9.95e-4 (favourable) Expressed in all Expressed in all small intestine: 25.7 BAP1 hucep-6, KIAA0272, UCHL2 ENSG00000163930 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 3 52401013-52410350 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004322, HPA028814, HPA028815, HPA055560 Approved Validated Nucleoplasm
Cytosol Renal cancer:3.29e-7 (favourable) Expressed in all Expressed in all testis: 118.1 BLMH BH ENSG00000108578 Bleomycin hydrolase 17 30248195-30292056 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039548, HPA064307 Supported Supported Nucleoplasm
Nuclear bodies
Cytosol Expressed in all Expressed in all skin: 140.2 CAPN1 CANP, CANPL1, muCANP, muCL ENSG00000014216 Calpain 1, (mu/I) large subunit 11 65180566-65212006 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005992 Supported Supported Cytosol Renal cancer:7.06e-8 (favourable), Pancreatic cancer:4.30e-4 (unfavourable) Expressed in all Expressed in all esophagus: 245.3 CAPN10 ENSG00000142330 Calpain 10 2 240586716-240617705 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004170, HPA056098 Approved Approved Nucleoplasm
Cytosol Liver cancer:4.78e-6 (unfavourable), Pancreatic cancer:7.94e-5 (favourable), Head and neck cancer:8.47e-5 (favourable) Expressed in all Expressed in all spleen: 15.5 CAPN11 ENSG00000137225 Calpain 11 6 44158811-44184402 Enzymes, Predicted intracellular proteins Evidence at protein level CAB018070, HPA030955 Supported Not detected Tissue enriched 32 testis: 54.7 adipose tissue,breast: 1.6 CAPN12 ENSG00000182472 Calpain 12 19 38730187-38769904 Enzymes, Predicted intracellular proteins Evidence at protein level HPA043492, HPA053322 Uncertain Approved Nucleoplasm
Focal adhesion sites Renal cancer:5.90e-6 (unfavourable) Mixed Tissue enriched 7 gallbladder: 35.0 cervix, uterine: 4.7 CAPN13 FLJ23523 ENSG00000162949 Calpain 13 2 30722771-30820542 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029496, HPA029497, HPA030034 Uncertain Approved Nucleoplasm Mixed Tissue enhanced rectum: 27.2;small intestine: 33.1;stomach: 26.3 duodenum: 21.4 CAPN15 SOLH ENSG00000103326 Calpain 15 16 527717-554636 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011960 Uncertain Approved Nucleus Expressed in all Mixed small intestine: 17.3 CAPN2 CANPL2, CANPml, mCANP ENSG00000162909 Calpain 2, (m/II) large subunit 1 223701593-223776018 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA024470 Approved Supported Cytosol Renal cancer:2.19e-4 (favourable), Pancreatic cancer:2.50e-4 (unfavourable), Urothelial cancer:6.21e-4 (unfavourable) Expressed in all Expressed in all lung: 267.2 CAPN3 CANP3, LGMD2, LGMD2A, nCL-1, p94 ENSG00000092529 Calpain 3 15 42359500-42412318 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA040052 Approved Tissue enriched Expressed in all skeletal muscle: 357.7 CAPN5 ADNIV, HTRA3, nCL-3, VRNI ENSG00000149260 Calpain 5 11 77066932-77126155 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB033237, HPA072319 Uncertain Approved Nucleus
Cytosol Endometrial cancer:2.16e-6 (unfavourable) Expressed in all Mixed colon: 62.2 CAPN6 CalpM, CANPX, CAPNX ENSG00000077274 Calpain 6 X 111245103-111270523 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA040383 Uncertain Cytosol Tissue enhanced Tissue enhanced epididymis: 251.6;placenta: 116.3;seminal vesicle: 99.3 endometrium: 36.9 CAPN7 PalBH ENSG00000131375 Calpain 7 3 15206152-15252918 Enzymes, Predicted intracellular proteins Evidence at protein level HPA046617 Uncertain Approved Nucleoplasm
Nuclear bodies
Cytosol Colorectal cancer:4.85e-5 (favourable) Expressed in all Expressed in all thyroid gland: 39.2 CAPN8 nCL-2 ENSG00000203697 Calpain 8 1 223538007-223665734 Enzymes, Predicted intracellular proteins Evidence at protein level HPA073939 Approved Nucleoplasm
Nuclear membrane
Vesicles Tissue enhanced Tissue enriched 8 stomach: 288.4 rectum: 37.8 CAPN9 GC36, nCL-4 ENSG00000135773 Calpain 9 1 230747384-230802003 Enzymes, Predicted intracellular proteins Evidence at protein level HPA020398, CAB033483 Supported Mixed Tissue enhanced rectum: 25.6;stomach: 58.8 colon: 14.6 CASP1 ICE, IL1BC ENSG00000137752 Caspase 1, apoptosis-related cysteine peptidase 11 105025443-105035250 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB002685, HPA003056 Approved Supported Nucleoplasm
Cytosol Renal cancer:3.11e-4 (unfavourable) Expressed in all Mixed small intestine: 142.8 CASP10 MCH4 ENSG00000003400 Caspase 10, apoptosis-related cysteine peptidase 2 201182881-201229406 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB003780, HPA017059 Approved Uncertain Golgi apparatus
Vesicles Renal cancer:6.05e-7 (unfavourable), Liver cancer:8.54e-4 (unfavourable) Expressed in all Mixed spleen: 24.6 CASP14 MGC119078, MGC119079, MICE ENSG00000105141 Caspase 14, apoptosis-related cysteine peptidase 19 15049384-15058293 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB010059, HPA027062 Supported Supported Cytosol Pancreatic cancer:5.96e-4 (unfavourable), Lung cancer:7.59e-4 (unfavourable) Tissue enhanced Tissue enriched 56 skin: 560.0 breast: 10.0 CASP2 ICH1, MGC2181, NEDD2, PPP1R57 ENSG00000106144 Caspase 2, apoptosis-related cysteine peptidase 7 143288215-143307696 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB012175, HPA050678 Approved Approved Nucleoplasm Renal cancer:5.01e-6 (unfavourable), Liver cancer:2.34e-4 (unfavourable), Ovarian cancer:2.89e-4 (favourable), Cervical cancer:7.38e-4 (favourable) Expressed in all Expressed in all lymph node: 25.3 CASP3 apopain, CPP32, CPP32B, Yama ENSG00000164305 Caspase 3, apoptosis-related cysteine peptidase 4 184627696-184649509 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level CAB000091, HPA002643, CAB008381 Approved Supported Nucleoplasm
Mitochondria Renal cancer:2.30e-5 (unfavourable), Endometrial cancer:2.24e-4 (favourable) Expressed in all Expressed in all duodenum: 55.9 CASP4 ICE(rel)II, ICH-2, TX ENSG00000196954 Caspase 4, apoptosis-related cysteine peptidase 11 104942866-104969436 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA027588, CAB037167 Approved Approved Plasma membrane
Cytosol Renal cancer:3.27e-11 (unfavourable) Expressed in all Expressed in all placenta: 71.5 CASP5 ICE(rel)III ENSG00000137757 Caspase 5, apoptosis-related cysteine peptidase 11 104994235-105023168 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA040937 Uncertain Group enriched Group enriched 6 appendix: 20.7;colon: 16.2;duodenum: 10.4;rectum: 14.7;small intestine: 19.3 smooth muscle: 2.6 CASP6 MCH2 ENSG00000138794 Caspase 6, apoptosis-related cysteine peptidase 4 109688622-109703583 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB003775, HPA011337, HPA024303 Supported Supported Nucleus
Cytosol Colorectal cancer:2.64e-5 (favourable), Urothelial cancer:9.93e-4 (favourable) Expressed in all Expressed in all small intestine: 47.1 CASP7 CMH-1, ICE-LAP3, MCH3 ENSG00000165806 Caspase 7, apoptosis-related cysteine peptidase 10 113679162-113730907 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level CAB025563 Approved Breast cancer:2.11e-4 (favourable), Renal cancer:5.90e-4 (unfavourable) Expressed in all Expressed in all small intestine: 75.9 CASP8 Casp-8, FLICE, MACH, MCH5 ENSG00000064012 Caspase 8, apoptosis-related cysteine peptidase 2 201233443-201287711 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA001302, CAB002047, HPA005688, HPA006191 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.27e-6 (unfavourable), Ovarian cancer:1.25e-4 (favourable), Liver cancer:3.02e-4 (unfavourable) Expressed in all Expressed in all spleen: 45.6 CASP9 APAF-3, ICE-LAP6, MCH6, PPP1R56 ENSG00000132906 Caspase 9, apoptosis-related cysteine peptidase 1 15490832-15526534 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA001473, CAB004348, HPA046488 Approved Approved Mitochondria Urothelial cancer:1.67e-5 (favourable), Breast cancer:5.91e-4 (favourable) Expressed in all Expressed in all adrenal gland: 37.3 CFLAR c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT ENSG00000003402 CASP8 and FADD-like apoptosis regulator 2 201116104-201176687 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA019044, CAB022157, CAB025216 Uncertain Supported Nucleus
Nuclear bodies
Plasma membrane
Cytosol Head and neck cancer:2.79e-4 (favourable) Expressed in all Expressed in all bone marrow: 160.5 CTSB ENSG00000164733 Cathepsin B 8 11842524-11869448 Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000457, HPA018156 Uncertain Supported Nucleoli
Vesicles Thyroid cancer:5.76e-4 (favourable), Urothelial cancer:9.02e-4 (unfavourable) Expressed in all Expressed in all thyroid gland: 2885.5 CTSC DPP1, PALS, PLS ENSG00000109861 Cathepsin C 11 88293592-88337787 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB025364, HPA066610, HPA068434 Supported Supported Vesicles Liver cancer:9.30e-5 (unfavourable), Renal cancer:4.80e-4 (favourable) Expressed in all Expressed in all lung: 390.6 CTSF CATSF, CLN13 ENSG00000174080 Cathepsin F 11 66563463-66568841 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB002141, HPA031431, HPA055610 Approved Approved Vesicles
Plasma membrane
Cytosol Renal cancer:8.92e-7 (favourable) Expressed in all Expressed in all ovary: 140.1 CTSH ACC-4, ACC-5, ACC4, ACC5, CPSB ENSG00000103811 Cathepsin H 15 78921058-78949574 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level CAB000458, HPA003524 Supported Supported Vesicles
Cytosol
Cytoplasmic bodies Endometrial cancer:6.90e-4 (favourable) Expressed in all Expressed in all lung: 570.4 CTSK CTSO, CTSO2, PKND, PYCD ENSG00000143387 Cathepsin K 1 150796208-150808323 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA050346 Supported Vesicles Renal cancer:7.12e-5 (unfavourable) Expressed in all Expressed in all cervix, uterine: 571.4 CTSL CTSL1, FLJ31037 ENSG00000135047 Cathepsin L 9 87725519-87731393 Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000459 Supported Lung cancer:5.15e-5 (unfavourable), Renal cancer:4.34e-4 (favourable), Glioma:4.94e-4 (unfavourable) Expressed in all Expressed in all placenta: 744.0 CTSO CTSO1 ENSG00000256043 Cathepsin O 4 155924118-155953917 Enzymes, Predicted secreted proteins Evidence at protein level HPA002041 Approved Expressed in all Expressed in all gallbladder: 32.5 CTSS ENSG00000163131 Cathepsin S 1 150730196-150765957 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB000460, HPA002988 Supported Approved Vesicles Expressed in all Expressed in all spleen: 381.4 CTSV CTSL2, CTSU ENSG00000136943 Cathepsin V 9 97029679-97039643 Enzymes, Predicted secreted proteins Evidence at protein level CAB017112 Uncertain Approved Nucleus
Nucleoli fibrillar center
Plasma membrane
Cytosol Liver cancer:2.83e-5 (unfavourable), Urothelial cancer:2.39e-4 (unfavourable), Pancreatic cancer:2.87e-4 (unfavourable), Endometrial cancer:8.41e-4 (favourable) Mixed Tissue enhanced cervix, uterine: 68.9;skin: 64.3;testis: 131.2 placenta: 25.7 CTSW ENSG00000172543 Cathepsin W 11 65879809-65883741 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB016345 Supported Endometrial cancer:8.36e-6 (favourable), Renal cancer:8.84e-6 (unfavourable), Breast cancer:3.06e-4 (favourable), Head and neck cancer:9.89e-4 (favourable) Expressed in all Tissue enhanced bone marrow: 70.8;spleen: 61.4 lung: 36.5 CTSZ CTSX ENSG00000101160 Cathepsin Z 20 58995185-59007247 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB025114, HPA049876, HPA053504 Supported Supported Vesicles Renal cancer:5.72e-5 (unfavourable) Expressed in all Expressed in all lung: 477.4 CYLD CYLD1, KIAA0849, USPL2 ENSG00000083799 Cylindromatosis (turban tumor syndrome) 16 50742050-50801935 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011713, HPA050095 Approved Supported Nucleoplasm
Microtubule organizing center Expressed in all Expressed in all testis: 70.2 ESPL1 ESP1, KIAA0165, SEPA ENSG00000135476 Extra spindle pole bodies like 1, separase 12 53268299-53293643 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level CAB012185 Uncertain Supported Nucleoplasm
Vesicles Liver cancer:2.01e-5 (unfavourable), Endometrial cancer:5.32e-5 (unfavourable), Stomach cancer:7.10e-4 (favourable), Lung cancer:7.14e-4 (unfavourable) Mixed Tissue enhanced esophagus: 11.4;testis: 10.6 lymph node: 4.9 FAM105A FLJ11127, NET20 ENSG00000145569 Family with sequence similarity 105, member A 5 14581775-14615007 Enzymes, Predicted membrane proteins Evidence at protein level HPA046638 Uncertain Approved Nucleoli
Cytosol Pancreatic cancer:1.02e-4 (favourable), Testis cancer:7.62e-4 (unfavourable) Expressed in all Mixed bone marrow: 35.6 GGH ENSG00000137563 Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 8 63015079-63039171 Enzymes, Plasma proteins, Predicted secreted proteins Evidence at protein level CAB019296, HPA025226 Approved Endometrial cancer:3.99e-7 (unfavourable), Lung cancer:1.65e-4 (unfavourable) Expressed in all Tissue enhanced kidney: 89.2 liver: 62.8 LGMN LGMN1, PRSC1 ENSG00000100600 Legumain 14 92703807-92748702 Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA000799, HPA001426 Supported Approved Cytosol Renal cancer:4.70e-4 (favourable) Expressed in all Expressed in all placenta: 357.3 MALT1 MLT, PCASP1 ENSG00000172175 MALT1 paracaspase 18 58671386-58754477 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB004494, HPA048432 Supported Supported Nucleoli
Cytosol Expressed in all Expressed in all lymph node: 34.4 OTUB1 FLJ20113, FLJ40710 ENSG00000167770 OTU deubiquitinase, ubiquitin aldehyde binding 1 11 63985853-64001811 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA039176, CAB072836 Approved Supported Approved Nucleus
Cytosol Head and neck cancer:3.05e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 116.3 OTUB2 C14orf137, FLJ21916, MGC3102 ENSG00000089723 OTU deubiquitinase, ubiquitin aldehyde binding 2 14 94026329-94048930 Enzymes, Predicted intracellular proteins Evidence at protein level HPA002329, HPA075090 Supported Approved Nucleoplasm Mixed Tissue enhanced testis: 9.8 skin: 4.7 OTUD5 DKFZp761A052, DUBA ENSG00000068308 OTU deubiquitinase 5 X 48922028-48958386 Enzymes, Predicted intracellular proteins Evidence at protein level HPA017375 Approved Approved Nucleus
Nucleoli fibrillar center
Cytosol Lung cancer:1.48e-4 (favourable), Pancreatic cancer:8.20e-4 (favourable), Cervical cancer:9.57e-4 (favourable) Expressed in all Expressed in all cerebral cortex: 70.1 OTUD7A C15orf16, CEZANNE2, OTUD7 ENSG00000169918 OTU deubiquitinase 7A 15 31475398-31870789 Cancer-related genes, Enzymes, Predicted intracellular proteins Evidence at protein level HPA044554 Uncertain Approved Nucleoli
Cytosol Mixed Tissue enhanced cerebral cortex: 13.5 testis: 5.1 OTUD7B CEZANNE, ZA20D1 ENSG00000264522 OTU deubiquitinase 7B 1 149937812-150010676 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027045 Supported Approved Nucleoplasm
Microtubules Melanoma:5.09e-5 (favourable), Endometrial cancer:7.47e-4 (favourable) Expressed in all Mixed testis: 23.5 OTULIN FAM105B, FLJ34884 ENSG00000154124 OTU deubiquitinase with linear linkage specificity 5 14664664-14699711 Enzymes, Predicted intracellular proteins Evidence at protein level HPA051074 Uncertain Approved Plasma membrane
Mitochondria Renal cancer:2.59e-7 (unfavourable) Expressed in all Expressed in all bone marrow: 17.2 PARK7 DJ-1, DJ1 ENSG00000116288 Parkinson protein 7 1 7954291-7985505 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA004190, CAB005870 Supported Supported Nucleus
Cytosol Expressed in all Expressed in all parathyroid gland: 505.2 PDDC1 FLJ34283 ENSG00000177225 Parkinson disease 7 domain containing 1 11 767220-777488 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA008812 Uncertain Supported Nucleoplasm Renal cancer:3.79e-5 (favourable), Liver cancer:3.98e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 31.8 PGPEP1 Pcp, PGP, PGP-I, PGPI ENSG00000130517 Pyroglutamyl-peptidase I 19 18340587-18369950 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035368, HPA055277 Approved Approved Golgi apparatus Renal cancer:3.71e-8 (favourable), Pancreatic cancer:1.71e-4 (favourable), Melanoma:6.80e-4 (favourable) Expressed in all Expressed in all kidney: 29.2 PGPEP1L ENSG00000183571 Pyroglutamyl-peptidase I-like 15 98968230-99007795 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA041781 Uncertain Not detected Group enriched 6 heart muscle: 2.2;skeletal muscle: 9.6;testis: 3.3 breast: 0.8 PIGK GPI8, hGPI8 ENSG00000142892 Phosphatidylinositol glycan anchor biosynthesis, class K 1 77088990-77219430 Enzymes, Predicted membrane proteins, Predicted secreted proteins Evidence at protein level HPA056383, HPA057040 Uncertain Liver cancer:4.68e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 28.0 SCRN1 KIAA0193 ENSG00000136193 Secernin 1 7 29920103-29990289 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024517 Approved Approved Cytosol Renal cancer:1.15e-5 (favourable), Endometrial cancer:4.00e-5 (unfavourable), Urothelial cancer:2.60e-4 (unfavourable), Ovarian cancer:7.27e-4 (unfavourable), Breast cancer:8.32e-4 (unfavourable), Cervical cancer:8.46e-4 (unfavourable) Expressed in all Tissue enhanced cerebral cortex: 172.5 parathyroid gland: 126.6 SCRN2 ENSG00000141295 Secernin 2 17 47837692-47841333 Enzymes, Predicted intracellular proteins Evidence at protein level HPA022934, HPA023434 Supported Supported Nucleoplasm
Golgi apparatus Liver cancer:3.86e-4 (favourable), Urothelial cancer:5.83e-4 (favourable) Expressed in all Expressed in all adipose tissue: 84.2 SCRN3 FLJ23142 ENSG00000144306 Secernin 3 2 174395730-174429575 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034689, HPA034690 Approved Approved Vesicles
Cytosol Expressed in all Expressed in all parathyroid gland: 47.7 SENP1 ENSG00000079387 SUMO1/sentrin specific peptidase 1 12 48042898-48106308 Enzymes, Predicted intracellular proteins Evidence at protein level HPA011765, HPA046491 Uncertain Validated Nucleus
Focal adhesion sites Liver cancer:7.72e-5 (unfavourable), Renal cancer:8.37e-4 (unfavourable) Expressed in all Tissue enriched 8 testis: 109.5 lymph node: 13.4 SENP2 AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2 ENSG00000163904 SUMO1/sentrin/SMT3 specific peptidase 2 3 185582496-185633551 Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters Evidence at protein level HPA029247, HPA029248 Approved Supported Cytosol Endometrial cancer:7.98e-5 (unfavourable) Expressed in all Expressed in all testis: 26.8 SENP3 DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1 ENSG00000161956 SUMO1/sentrin/SMT3 specific peptidase 3 17 7561875-7571969 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA060290 Supported Supported Nucleus
Nucleoli Pancreatic cancer:6.22e-5 (favourable) Expressed in all Expressed in all testis: 57.1 SENP6 KIAA0797, SUSP1 ENSG00000112701 SUMO1/sentrin specific peptidase 6 6 75601509-75718278 Enzymes, Predicted intracellular proteins Evidence at protein level HPA024376 Approved Supported Nucleoplasm
Cytosol Thyroid cancer:2.83e-5 (unfavourable), Renal cancer:6.09e-4 (unfavourable) Expressed in all Expressed in all parathyroid gland: 73.9 SENP7 ENSG00000138468 SUMO1/sentrin specific peptidase 7 3 101324205-101513241 Enzymes, Predicted intracellular proteins Evidence at protein level HPA027259 Approved Approved Nucleoplasm
Cytosol Head and neck cancer:4.23e-4 (favourable) Expressed in all Expressed in all endometrium: 44.0 SENP8 DEN1, HsT17512, NEDP1, PRSC2 ENSG00000166192 SUMO/sentrin peptidase family member, NEDD8 specific 15 72114258-72143688 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036273 Approved Approved Nucleoplasm
Vesicles Mixed Tissue enhanced testis: 27.8 thyroid gland: 8.5 TINAG ENSG00000137251 Tubulointerstitial nephritis antigen 6 54307859-54390152 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035427, HPA041055 Approved Approved Vesicles Liver cancer:2.05e-5 (unfavourable), Renal cancer:8.75e-5 (favourable) Tissue enhanced Tissue enriched 7 kidney: 112.9 small intestine: 16.0 TINAGL1 ARG1, LCN7, LIECG3, P3ECSL, TINAGRP ENSG00000142910 Tubulointerstitial nephritis antigen-like 1 1 31576485-31587686 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA048695 Approved Renal cancer:3.65e-6 (favourable), Thyroid cancer:9.64e-4 (favourable) Expressed in all Tissue enhanced placenta: 267.7 adipose tissue: 102.4 TNFAIP3 A20, OTUD7C ENSG00000118503 Tumor necrosis factor, alpha-induced protein 3 6 137867188-137883312 Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA002116 Approved Approved Centrosome
Cytosol Renal cancer:6.05e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 345.8 UCHL1 PARK5, PGP9.5, Uch-L1 ENSG00000154277 Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 4 41256413-41268455 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB002580, HPA005993 Supported Validated Nucleoplasm
Cytosol Endometrial cancer:4.08e-5 (unfavourable), Urothelial cancer:1.93e-4 (unfavourable) Expressed in all Tissue enriched 7 cerebral cortex: 788.3 adrenal gland: 108.6 UCHL3 ENSG00000118939 Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 13 75549480-75606020 Enzymes, Predicted intracellular proteins Evidence at protein level HPA019678, CAB037139, CAB037208 Approved Supported Nucleus
Cytosol Liver cancer:6.41e-4 (unfavourable) Expressed in all Expressed in all testis: 90.1 UCHL5 CGI-70, INO80R, UCH37 ENSG00000116750 Ubiquitin carboxyl-terminal hydrolase L5 1 193012250-193060080 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA005908, HPA006069, HPA075383 Approved Approved Approved Nucleoplasm
Mitochondria Thyroid cancer:7.10e-5 (unfavourable) Expressed in all Expressed in all cerebral cortex: 43.1 UFSP1 UFSP ENSG00000176125 UFM1-specific peptidase 1 (non-functional) 7 100888723-100889718 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA027099 Uncertain Expressed in all Mixed adipose tissue: 2.0 UFSP2 C4orf20, FLJ11200 ENSG00000109775 UFM1-specific peptidase 2 4 185399540-185425985 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA039985, HPA043298 Approved Approved Nucleus
Cytosol Renal cancer:1.07e-8 (favourable) Expressed in all Expressed in all thyroid gland: 53.8 USP1 ENSG00000162607 Ubiquitin specific peptidase 1 1 62436297-62451804 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA028387, HPA028440 Approved Supported Nucleoplasm Liver cancer:5.81e-5 (unfavourable) Expressed in all Expressed in all testis: 91.8 USP10 KIAA0190, UBPO ENSG00000103194 Ubiquitin specific peptidase 10 16 84699978-84779922 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006731, HPA006749 Approved Validated Nucleoplasm
Cytosol Renal cancer:1.00e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 61.9 USP11 UHX1 ENSG00000102226 Ubiquitin specific peptidase 11 X 47232690-47248328 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA003103, HPA037536 Supported Approved Supported Nucleoplasm Renal cancer:4.13e-5 (favourable), Endometrial cancer:2.95e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 213.4 USP12 USP12L1 ENSG00000152484 Ubiquitin specific peptidase 12 13 27066142-27171896 Enzymes, Predicted intracellular proteins Evidence at protein level HPA007288 Uncertain Expressed in all Expressed in all bone marrow: 45.8 USP13 IsoT-3 ENSG00000058056 Ubiquitin specific peptidase 13 (isopeptidase T-3) 3 179652755-179789401 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA004827 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:3.46e-6 (unfavourable), Liver cancer:2.40e-5 (unfavourable), Urothelial cancer:3.06e-4 (unfavourable) Expressed in all Expressed in all skeletal muscle: 52.2 USP14 TGT ENSG00000101557 Ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 18 158383-214629 Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA001308 Approved Supported Cytosol Liver cancer:4.30e-5 (unfavourable), Head and neck cancer:7.81e-5 (unfavourable), Ovarian cancer:7.91e-4 (favourable) Expressed in all Expressed in all prostate: 49.2 USP15 KIAA0529, UNPH4 ENSG00000135655 Ubiquitin specific peptidase 15 12 62260338-62417431 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006237, HPA006428, HPA071014 Approved Validated Cytosol Renal cancer:1.58e-5 (unfavourable), Liver cancer:8.04e-4 (unfavourable) Expressed in all Expressed in all bone marrow: 121.9 USP16 Ubp-M ENSG00000156256 Ubiquitin specific peptidase 16 21 29024629-29054488 Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA021140 Supported Approved Nucleoplasm
Cytosol Expressed in all Expressed in all parathyroid gland: 56.2 USP17L1 USP17L1P ENSG00000230549 Ubiquitin specific peptidase 17-like family member 1 8 7332387-7333979 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected cerebral cortex: 0.3 USP17L10 ENSG00000231396 Ubiquitin specific peptidase 17-like family member 10 4 9210657-9212608 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L11 ENSG00000233136 Ubiquitin specific peptidase 17-like family member 11 4 9215405-9217356 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA045642 Uncertain Not detected Tissue enriched 11 epididymis: 2.2 thyroid gland: 0.2 USP17L12 ENSG00000227551 Ubiquitin specific peptidase 17-like family member 12 4 9220152-9221744 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L13 ENSG00000232399 Ubiquitin specific peptidase 17-like family member 13 4 9224896-9226847 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L15 ENSG00000223569 Ubiquitin specific peptidase 17-like family member 15 4 9234385-9365080 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L17 ENSG00000249104 Ubiquitin specific peptidase 17-like family member 17 4 9243879-9245830 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L18 ENSG00000250844 Ubiquitin specific peptidase 17-like family member 18 4 9248630-9250581 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L19 ENSG00000248920 Ubiquitin specific peptidase 17-like family member 19 4 9253378-9255329 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L2 DUB3 ENSG00000223443 Ubiquitin specific peptidase 17-like family member 2 8 12137168-12139077 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Tissue enriched 12 epididymis: 1.2 all non-specific tissues: 0.0 USP17L20 ENSG00000250745 Ubiquitin specific peptidase 17-like family member 20 4 9258124-9260075 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected epididymis: 0.4 USP17L21 ENSG00000249811 Ubiquitin specific peptidase 17-like family member 21 4 9262872-9264823 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L22 ENSG00000248933 Ubiquitin specific peptidase 17-like family member 22 4 9267619-9269570 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected epididymis: 0.2 USP17L24 ENSG00000232264 Ubiquitin specific peptidase 17-like family member 24 4 9325165-9327116 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L25 ENSG00000230430 Ubiquitin specific peptidase 17-like family member 25 4 9329911-9331862 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L26 ENSG00000229579 Ubiquitin specific peptidase 17-like family member 26 4 9334658-9336609 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L27 ENSG00000235780 Ubiquitin specific peptidase 17-like family member 27 4 9344148-9345740 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L28 ENSG00000231051 Ubiquitin specific peptidase 17-like family member 28 4 9348893-9350485 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L29 ENSG00000231637 Ubiquitin specific peptidase 17-like family member 29 4 9353638-9355230 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L3 USP17B, USP17F ENSG00000225327 Ubiquitin specific peptidase 17-like family member 3 8 7976393-7977985 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L30 ENSG00000228856 Ubiquitin specific peptidase 17-like family member 30 4 9363129-9364721 Enzymes, Predicted intracellular proteins Evidence at protein level HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L4 ENSG00000236125 Ubiquitin specific peptidase 17-like family member 4 8 7337115-7338707 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L5 ENSG00000227140 Ubiquitin specific peptidase 17-like family member 5 4 9339403-9340995 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP17L7 ENSG00000226430 Ubiquitin specific peptidase 17-like family member 7 8 12132417-12134444 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected epididymis: 0.8 USP17L8 ENSG00000237038 Ubiquitin specific peptidase 17-like family member 8 8 7971661-7977985 Enzymes, Predicted intracellular proteins No evidence HPA045642 Uncertain Not detected Not detected all non-specific tissues: 0.0 USP18 ENSG00000184979 Ubiquitin specific peptidase 18 22 18149899-18177397 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044768 Uncertain Approved Cytosol Expressed in all Mixed testis: 15.6 USP2 UBP41 ENSG00000036672 Ubiquitin specific peptidase 2 11 119355215-119381726 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006777, HPA007222 Approved Supported Plasma membrane
Cytosol Renal cancer:3.09e-11 (favourable) Expressed in all Tissue enhanced testis: 119.2 skeletal muscle: 59.3 USP20 KIAA1003 ENSG00000136878 Ubiquitin specific peptidase 20 9 129834698-129881838 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006287, HPA007008 Uncertain Approved Approved Nucleus
Plasma membrane
Cytosol Pancreatic cancer:1.54e-7 (favourable), Renal cancer:5.65e-5 (favourable), Colorectal cancer:2.48e-4 (unfavourable), Endometrial cancer:4.01e-4 (favourable), Cervical cancer:8.01e-4 (favourable) Expressed in all Expressed in all thyroid gland: 22.1 USP21 USP16, USP23 ENSG00000143258 Ubiquitin specific peptidase 21 1 161159450-161165723 Enzymes, Predicted intracellular proteins Evidence at protein level HPA028397 Uncertain Supported Supported Nucleoplasm
Plasma membrane
Cytosol Renal cancer:9.50e-6 (unfavourable), Urothelial cancer:3.35e-5 (favourable), Liver cancer:1.68e-4 (unfavourable), Endometrial cancer:7.05e-4 (unfavourable) Expressed in all Expressed in all fallopian tube: 45.2 USP22 KIAA1063, USP3L ENSG00000124422 Ubiquitin specific peptidase 22 17 20999593-21043760 Enzymes, Predicted intracellular proteins Evidence at protein level HPA044980 Supported Supported Nuclear speckles Renal cancer:1.53e-7 (favourable), Liver cancer:9.66e-4 (unfavourable) Expressed in all Expressed in all cerebral cortex: 154.5 USP24 KIAA1057 ENSG00000162402 Ubiquitin specific peptidase 24 1 55066359-55215113 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026723, HPA028428, HPA067124 Approved Supported Nucleoplasm
Cytosol Liver cancer:1.34e-7 (unfavourable) Expressed in all Expressed in all parathyroid gland: 37.4 USP25 USP21 ENSG00000155313 Ubiquitin specific peptidase 25 21 15730025-15880069 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA018297, HPA024142 Approved Supported Cytosol Expressed in all Expressed in all testis: 97.1 USP27X USP27 ENSG00000273820 Ubiquitin specific peptidase 27, X-linked X 49879948-49882565 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA077264 Approved Vesicles Liver cancer:6.14e-4 (unfavourable), Pancreatic cancer:9.31e-4 (favourable) Expressed in all Tissue enhanced placenta: 19.6 cerebral cortex: 10.4 USP28 KIAA1515 ENSG00000048028 Ubiquitin specific peptidase 28 11 113797874-113875570 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006778, HPA006779 Supported Supported Nucleoplasm
Nuclear bodies Expressed in all Expressed in all heart muscle: 39.8 USP29 ENSG00000131864 Ubiquitin specific peptidase 29 19 57119138-57131926 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA021064 Uncertain Not detected Tissue enriched 5 testis: 9.1 skin: 1.7 USP3 ENSG00000140455 Ubiquitin specific peptidase 3 15 63504511-63594640 Enzymes, Predicted intracellular proteins, Predicted secreted proteins Evidence at protein level HPA053275, HPA060513 Supported Nucleus Urothelial cancer:1.38e-4 (favourable) Expressed in all Expressed in all bone marrow: 32.1 USP30 FLJ40511, MGC10702 ENSG00000135093 Ubiquitin specific peptidase 30 12 109023089-109088026 Enzymes, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA016952 Approved Renal cancer:5.23e-6 (favourable) Expressed in all Expressed in all testis: 25.5 USP31 KIAA1203 ENSG00000103404 Ubiquitin specific peptidase 31 16 23061406-23149270 Enzymes, Predicted intracellular proteins Evidence at protein level HPA006937 Uncertain Approved Cytosol Renal cancer:4.41e-5 (unfavourable) Expressed in all Mixed testis: 22.2 USP32 NY-REN-60, USP10 ENSG00000170832 Ubiquitin specific peptidase 32 17 60179094-60422470 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA044365 Approved Approved Golgi apparatus
Cytosol Endometrial cancer:1.50e-4 (unfavourable) Expressed in all Expressed in all testis: 154.7 USP33 KIAA1097, VDU1 ENSG00000077254 Ubiquitin specific peptidase 33 1 77695987-77759852 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005719 Uncertain Supported Nucleoplasm
Golgi apparatus Expressed in all Expressed in all parathyroid gland: 55.0 USP34 KIAA0570, KIAA0729 ENSG00000115464 Ubiquitin specific peptidase 34 2 61187463-61470769 Enzymes, Predicted intracellular proteins Evidence at protein level HPA025815, HPA070764 Uncertain Approved Nucleus Expressed in all Expressed in all testis: 61.1 USP35 KIAA1372 ENSG00000118369 Ubiquitin specific peptidase 35 11 78188812-78214711 Enzymes, Predicted intracellular proteins Evidence at protein level HPA055213, HPA058592 Uncertain Approved Nucleus
Nucleoli fibrillar center Expressed in all Tissue enhanced parathyroid gland: 33.6 adrenal gland: 14.9 USP36 FLJ12851, KIAA1453 ENSG00000055483 Ubiquitin specific peptidase 36 17 78787381-78841441 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA012082, HPA012395, HPA052860 Uncertain Approved Validated Nucleoli
Nuclear speckles Endometrial cancer:5.18e-5 (unfavourable) Expressed in all Expressed in all skin: 38.4 USP37 KIAA1594 ENSG00000135913 Ubiquitin specific peptidase 37 2 218450251-218568361 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA045160 Approved Approved Nucleus
Nucleoli Head and neck cancer:2.85e-4 (favourable) Mixed Mixed testis: 23.3 USP38 HP43.8KD, KIAA1891 ENSG00000170185 Ubiquitin specific peptidase 38 4 143184917-143223830 Enzymes, Predicted intracellular proteins Evidence at protein level HPA036990, HPA047948 Uncertain Approved Nucleoplasm
Cytosol Renal cancer:1.20e-4 (favourable) Expressed in all Expressed in all parathyroid gland: 13.8 USP39 CGI-21, SAD1, SNRNP65 ENSG00000168883 Ubiquitin specific peptidase 39 2 85602856-85649282 Enzymes, Predicted intracellular proteins Evidence at protein level HPA034823 Approved Supported Nucleoplasm Renal cancer:4.05e-7 (unfavourable), Liver cancer:2.84e-6 (unfavourable), Endometrial cancer:5.52e-4 (unfavourable) Expressed in all Expressed in all placenta: 38.1 USP4 UNP, Unph ENSG00000114316 Ubiquitin specific peptidase 4 (proto-oncogene) 3 49277831-49340712 Enzymes, Predicted intracellular proteins Evidence at protein level HPA018499 Approved Supported Plasma membrane
Cytosol Renal cancer:4.29e-5 (favourable), Lung cancer:4.46e-5 (favourable) Expressed in all Expressed in all testis: 56.7 USP40 FLJ10785 ENSG00000085982 Ubiquitin specific peptidase 40 2 233475520-233566782 Enzymes, Predicted intracellular proteins Evidence at protein level HPA005821 Uncertain Approved Vesicles Expressed in all Expressed in all parathyroid gland: 30.9 USP42 FLJ12697 ENSG00000106346 Ubiquitin specific peptidase 42 7 6104884-6161564 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006752, HPA064800 Uncertain Approved Nucleus Expressed in all Tissue enhanced testis: 27.6 parathyroid gland: 8.6 USP43 FLJ30626 ENSG00000154914 Ubiquitin specific peptidase 43 17 9644698-9729691 Enzymes, Predicted intracellular proteins Evidence at protein level HPA023389, HPA027762 Uncertain Stomach cancer:5.39e-4 (favourable) Mixed Mixed placenta: 11.6 USP44 FLJ14528 ENSG00000136014 Ubiquitin specific peptidase 44 12 95516560-95551490 Enzymes, Predicted intracellular proteins Evidence at protein level HPA026543 Approved Nucleoli fibrillar center
Microtubules Tissue enhanced Tissue enriched 7 testis: 43.4 parathyroid gland: 5.9 USP45 MGC14793 ENSG00000123552 Ubiquitin specific peptidase 45 6 99432379-99521728 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029602, HPA029604 Uncertain Approved Nucleus
Cytosol Expressed in all Mixed gallbladder: 14.0 USP46 FLJ12552 ENSG00000109189 Ubiquitin specific peptidase 46 4 52590972-52659335 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA007288, CAB076369, CAB076370 Uncertain Validated Nucleoli Expressed in all Expressed in all cerebral cortex: 44.8 USP47 ENSG00000170242 Ubiquitin specific peptidase 47 11 11841423-11959323 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029286, HPA029289 Supported Approved Intermediate filaments Expressed in all Expressed in all parathyroid gland: 75.5 USP48 FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31 ENSG00000090686 Ubiquitin specific peptidase 48 1 21678298-21783606 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030045, HPA030046 Approved Approved Supported Nucleoplasm
Mitochondria
Cytosol Liver cancer:6.09e-8 (unfavourable) Expressed in all Expressed in all adrenal gland: 54.3 USP49 MGC20741 ENSG00000164663 Ubiquitin specific peptidase 49 6 41789896-41895361 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA030254, HPA030255 Uncertain Mixed Mixed testis: 9.4 USP5 IsoT ENSG00000111667 Ubiquitin specific peptidase 5 (isopeptidase T) 12 6852128-6866632 Enzymes, Plasma proteins, Predicted intracellular proteins Evidence at protein level HPA006756 Uncertain Approved Nucleoplasm
Cytosol Expressed in all Expressed in all cerebral cortex: 87.6 USP50 ENSG00000170236 Ubiquitin specific peptidase 50 15 50500562-50546708 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA039470 Uncertain Not detected Tissue enriched 17 testis: 1.9 parathyroid gland: 0.1 USP51 ENSG00000247746 Ubiquitin specific peptidase 51 X 55484616-55489202 Enzymes, Predicted intracellular proteins Evidence at transcript level HPA001942 Uncertain Renal cancer:2.63e-5 (favourable), Ovarian cancer:5.70e-4 (favourable) Mixed Tissue enriched 7 epididymis: 60.9 parathyroid gland: 9.0 USP53 KIAA1350 ENSG00000145390 Ubiquitin specific peptidase 53 4 119212587-119295517 Enzymes, Predicted intracellular proteins Evidence at protein level HPA035844, HPA035845 Uncertain Approved Nucleoplasm
Golgi apparatus Renal cancer:3.58e-8 (favourable), Colorectal cancer:3.15e-6 (favourable), Prostate cancer:7.54e-6 (unfavourable) Expressed in all Mixed fallopian tube: 48.4 USP54 bA137L10.3, bA137L10.4, C10orf29, FLJ37318 ENSG00000166348 Ubiquitin specific peptidase 54 10 73497538-73625953 Enzymes, Predicted intracellular proteins Evidence at protein level HPA047663 Approved Approved Mitochondria Lung cancer:7.00e-4 (favourable) Expressed in all Tissue enhanced thyroid gland: 66.5 cerebral cortex: 33.1 USP6 HRP1, Tre-2, TRE17, Tre2, TRESMCR ENSG00000129204 Ubiquitin specific peptidase 6 17 5116438-5175034 Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA046969 Uncertain Uncertain Vesicles Tissue enriched Tissue enhanced testis: 17.8 skeletal muscle: 7.5 USP7 HAUSP ENSG00000187555 Ubiquitin specific peptidase 7 (herpes virus-associated) 16 8892094-8964514 Enzymes, Predicted intracellular proteins Evidence at protein level CAB008108, HPA015641 Approved Renal cancer:8.56e-5 (favourable) Expressed in all Expressed in all testis: 108.6 USP8 HumORF8, KIAA0055, SPG59, UBPY ENSG00000138592 Ubiquitin specific peptidase 8 15 50424380-50514419 Enzymes, Predicted intracellular proteins Evidence at protein level HPA004869, HPA050215 Uncertain Supported Golgi apparatus
Cytosol Renal cancer:1.29e-5 (favourable) Expressed in all Expressed in all parathyroid gland: 75.8 USP9X DFFRX, FAF, MRX99 ENSG00000124486 Ubiquitin specific peptidase 9, X-linked X 41085635-41236579 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level CAB011618, HPA047417, CAB070164 Approved Uncertain Vesicles Expressed in all Expressed in all parathyroid gland: 88.6 USP9Y DFFRY ENSG00000114374 Ubiquitin specific peptidase 9, Y-linked Y 12701231-12860839 Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins Evidence at protein level HPA057687 Uncertain Vesicles Tissue enhanced Tissue enhanced prostate: 10.1 epididymis,seminal vesicle: 6.7 USPL1 bA121O19.1, C13orf22, D13S106E ENSG00000132952 Ubiquitin specific peptidase like 1 13 30617693-30660770 Enzymes, Predicted intracellular proteins Evidence at protein level HPA039342, HPA040172 Uncertain Expressed in all Expressed in all testis: 40.3 ZRANB1 TRABID ENSG00000019995 Zinc finger, RAN-binding domain containing 1 10 124942123-124988189 Enzymes, Predicted intracellular proteins Evidence at protein level HPA029239, HPA029240, HPA029241 Approved Supported Nucleoplasm
Cytosol Expressed in all Expressed in all testis: 34.5