Gene Gene synonym Ensembl Gene description Chromosome Position Protein class Evidence Antibody Reliability (IH) Reliability (Mouse Brain) Reliability (IF) Subcellular location Prognostic p-value RNA cancer category RNA tissue category RNA TS RNA TS TPM TPM max in non-specific GPR119 GPCR2, hGPCR2 ENSG00000147262 G protein-coupled receptor 119 X 130384440-130385447 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Pancreatic cancer:6.93e-4 (favourable) Tissue enriched Not detected duodenum,pancreas: 0.6 GPR6 ENSG00000146360 G protein-coupled receptor 6 6 109978256-109980718 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Not detected Tissue enriched 16 cerebral cortex: 1.5 all non-specific tissues: 0.0 GPR65 hTDAG8, TDAG8 ENSG00000140030 G protein-coupled receptor 65 14 88005124-88014811 G-protein coupled receptors, Predicted membrane proteins Evidence at transcript level HPA054454 Approved Cytosol Renal cancer:4.99e-4 (unfavourable) Mixed Mixed spleen: 13.5 LPAR1 edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1 ENSG00000198121 Lysophosphatidic acid receptor 1 9 110873263-111038458 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA050667 Approved Nuclear speckles
Plasma membrane Expressed in all Mixed cervix, uterine: 90.9 LPAR2 EDG-4, EDG4, LPA2 ENSG00000064547 Lysophosphatidic acid receptor 2 19 19623668-19628930 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA019616 Approved Renal cancer:1.61e-7 (unfavourable), Stomach cancer:1.43e-4 (favourable) Expressed in all Mixed testis: 40.7 LPAR3 Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3 ENSG00000171517 Lysophosphatidic acid receptor 3 1 84811602-84893213 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013421 Uncertain Supported Plasma membrane Ovarian cancer:4.31e-5 (favourable) Tissue enhanced Tissue enhanced fallopian tube: 66.2 prostate: 21.5 LPAR4 GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9 ENSG00000147145 Lysophosphatidic acid receptor 4 X 78747709-78757094 G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters Evidence at protein level HPA054951, HPA055571 Uncertain Tissue enhanced Tissue enhanced ovary: 4.5 cerebral cortex: 2.2 LPAR5 GPR92, GPR93, KPG_010, LPA5 ENSG00000184574 Lysophosphatidic acid receptor 5 12 6618835-6636447 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA013170 Approved Thyroid cancer:6.56e-5 (favourable) Mixed Mixed tonsil: 11.0 LPAR6 P2RY5, P2Y5 ENSG00000139679 Lysophosphatidic acid receptor 6 13 48389567-48444704 Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins Evidence at protein level HPA028934, HPA076273 Approved Supported Vesicles
Plasma membrane Renal cancer:3.60e-4 (unfavourable), Lung cancer:6.22e-4 (favourable) Expressed in all Expressed in all placenta: 100.1 S1PR1 CD363, D1S3362, edg-1, EDG1 ENSG00000170989 Sphingosine-1-phosphate receptor 1 1 101236888-101241518 Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins, Transporters Evidence at protein level CAB010104, HPA075568 Supported Supported Vesicles Urothelial cancer:8.78e-4 (unfavourable) Expressed in all Expressed in all adipose tissue: 86.5 S1PR2 AGR16, EDG5, Gpcr13, H218 ENSG00000267534 Sphingosine-1-phosphate receptor 2 19 10221435-10231272 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA014307 Approved Renal cancer:4.36e-10 (unfavourable) Expressed in all Tissue enhanced placenta: 26.9 lymph node: 13.5 S1PR3 EDG-3, EDG3 ENSG00000213694 Sphingosine-1-phosphate receptor 3 9 88991447-89005010 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level Renal cancer:7.91e-6 (unfavourable), Colorectal cancer:1.30e-4 (unfavourable), Breast cancer:5.91e-4 (favourable) Expressed in all Mixed smooth muscle: 51.8 S1PR4 EDG6 ENSG00000125910 Sphingosine-1-phosphate receptor 4 19 3172346-3180332 G-protein coupled receptors, Predicted membrane proteins Evidence at protein level HPA060601, HPA067232 Uncertain Mitochondria Head and neck cancer:1.45e-6 (favourable), Cervical cancer:1.33e-4 (favourable), Endometrial cancer:2.22e-4 (favourable), Renal cancer:2.87e-4 (unfavourable), Breast cancer:3.13e-4 (favourable) Expressed in all Tissue enhanced lymph node: 18.3;spleen: 27.0 appendix: 14.5 S1PR5 Edg-8, EDG8 ENSG00000180739 Sphingosine-1-phosphate receptor 5 19 10512742-10517931 FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins Evidence at protein level HPA029683 Supported Renal cancer:6.71e-7 (unfavourable) Group enriched Tissue enhanced cerebral cortex: 14.9;skin: 22.1 spleen: 12.2