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Hepatocellular carcinomas as well as most malignant carcinoids, colorectal cancers and basal cell carcinomas displayed moderate cytoplasmic immunoreactivity. Remaining malignancies were weakly stained or negative.
C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008]