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ANO8

GENERAL INFORMATION

Gene name

 ANO8

Gene description

 Anoctamin 8

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA049206
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ANO8 (HGNC Symbol)

Synonyms

 KIAA1623, TMEM16H

Description

 Anoctamin 8 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.11

Chromosome location (bp)

 17323223 - 17334829

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000074855 (version 83.38)

Entrez gene

 57719

UniProt

 Q9HCE9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9HCE9

Antibodypedia

 ANO8 antibodies

PROTEIN BROWSER
ANO8-001
ANO8-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ANO8-001
ENSP00000159087
ENST00000159087
Q9HCE9 [Direct mapping]
Anoctamin-8
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
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GO:0005229 [intracellular calcium activated chloride channel activity]
GO:0005622 [intracellular]
GO:0005886 [plasma membrane]
GO:0006821 [chloride transport]
GO:0016021 [integral component of membrane]
GO:0034220 [ion transmembrane transport]
GO:0055085 [transmembrane transport]
GO:1902476 [chloride transmembrane transport]
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 1232 aa
136 kDa 		No 8
ANO8-201
ENSP00000486865
ENST00000630631
M0QYD2 [Direct mapping]
Anoctamin
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Show all
GO:0016021 [integral component of membrane]
Show all
 581 aa
65.6 kDa 		No 5

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.