The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Moderate granular cytoplasmic positivity was seen in most normal tissues. Gastrointestinal tract, parathyroid, adrenal gland, renal tubules and a subset of male genitalia showed strong cytoplasmic staining. Bile duct cells, glomeruli and skeletal myocytes were negative.
Gastrointestinal tract showed moderate to strong cytoplasmic staining. Endocrine glands, renal tubules, male genitalia, cells in CNS and heart muscle showed moderate staining.
Moderate to strong cytoplasmic positivity with a granular pattern was observed in most normal tissues. Glial cells and renal glomeruli were negative.
Normal tissues generally displayed moderate to strong cytoplasmic immunoreactivity with a granular pattern.