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A majority of malignant tissues displayed moderate cytoplasmic immunoreactivity. Several malignant lymphomas, gliomas and renal cancers were negative.
GENE INFORMATION
Gene name
GTPBP1 (HGNC Symbol)
Synonyms
GP-1, HSPC018
Description
GTP binding protein 1 (HGNC Symbol)
Entrez gene summary
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]