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Expression in ciliated cells in fallopian tube and respiratory tract.
ANTIBODY IHC RELIABILITY
Data reliability description
Presumed off target binding observed and disregarded. Pending external verification. Staining in respiratory epithelium can be compared with the lung RNAseq values.
This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]