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ABCA2
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TISSUE ATLAS PRIMARY DATA SPLEEN

GENE/PROTEIN

Antibody validation


Dictionary

Spleen

Tissue proteome

Spleen

SPLEEN - Expression summary

Protein expressioni

The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.

h
m
l
n

RNA expressioni

RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.

Read more

HPA:13.5TPM
GTEx:13.5RPKM
FANTOM5:6.6Tags Per Million

SPLEEN - Annotated protein expressioni

The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.

Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.

The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.

For histological reference, view the histological dictionary.

Annotated protein
expression

Cells in red pulp:Low
Cells in white pulp:Not detected
 

Antibody stainingi

This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.

Read more

Antibody HPA042886

 

Cells in red pulp

Low  

Cells in white pulp

Not detected  
 
 
 

SPLEEN - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Read more

Average TPM

13.5

overview Female, age 60 Sample 1
TPM: 12.6
Cell types%
Lymphocytes: 40
Macrophages: 30
Endothelial cells: 15
Fibroblasts: 5
Other cell types: 10
overview Male, age 17 Sample 2
TPM: 16.2
Cell types%
Lymphocytes: 40
Macrophages: 35
Endothelial cells: 15
Fibroblasts: 5
Other cell types: 5
overview Male, age 20 Sample 3
TPM: 12.2
Cell types%
Lymphocytes: 40
Macrophages: 30
Endothelial cells: 15
Fibroblasts: 5
Other cell types: 10
overview Female, age 19 Sample 4
TPM: 21.5
Cell types%
Lymphocytes: 40
Macrophages: 30
Endothelial cells: 15
Fibroblasts: 10
Other cell types: 5
overview Female, age 65 Sample 5
TPM: 4.8
Cell types%
Lymphocytes: 35
Macrophages: 30
Endothelial cells: 20
Fibroblasts: 10
Other cell types: 5

SPLEEN - GTEx RNA-seqi

RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.

Read more

Average RPKM

13.5

GTEx sample id

Sample description

RPKM

Spleen
RPKM: 13.5
Samples: 104

Max RPKM: 21.1
Min RPKM: 7.2
Std RPKM: 3.0
Median RPKM: 13.3
GTEX-11LCK-0126-SM-5A5M5 30-39 years, male 21.1
GTEX-UPK5-1626-SM-4JBHI 40-49 years, male 19.8
GTEX-X3Y1-0126-SM-4PQZA 40-49 years, male 19.6
GTEX-XQ8I-1726-SM-4BOQB 50-59 years, male 19.4
GTEX-Z9EW-0726-SM-5HL9H 40-49 years, male 19.0
GTEX-S4Z8-0226-SM-4AD5K 60-69 years, male 18.8
GTEX-QLQW-0126-SM-447BK 30-39 years, male 18.6
GTEX-XGQ4-0126-SM-4AT4H 50-59 years, male 18.6
GTEX-13111-0126-SM-5EGHO 50-59 years, male 18.2
GTEX-P4QS-0926-SM-48TBS 60-69 years, male 17.9
GTEX-OOBJ-0926-SM-48TDO 60-69 years, male 17.8
GTEX-ZVP2-0526-SM-51MSC 50-59 years, male 17.7
GTEX-QMRM-0226-SM-4R1K7 50-59 years, male 17.4
GTEX-WFON-0126-SM-4LVM9 40-49 years, male 17.3
GTEX-X585-1826-SM-4QAS3 50-59 years, male 16.9
GTEX-W5WG-0626-SM-4SOID 50-59 years, female 16.7
GTEX-12WSN-0126-SM-5DUX5 40-49 years, male 16.6
GTEX-13VXT-1326-SM-5LU3Y 20-29 years, female 16.6
GTEX-12WSG-0926-SM-5EGIH 50-59 years, female 16.5
GTEX-UJHI-0126-SM-4IHLP 50-59 years, female 16.3
GTEX-XUJ4-0226-SM-4BOP8 60-69 years, female 16.1
GTEX-11DXX-0726-SM-5H12X 60-69 years, female 16.0
GTEX-12WSJ-0526-SM-5GCOZ 40-49 years, female 16.0
GTEX-PLZ6-0126-SM-48TC6 30-39 years, male 15.9
GTEX-POMQ-0126-SM-48TD6 20-29 years, female 15.9
GTEX-Y3I4-0126-SM-4TT26 50-59 years, male 15.9
GTEX-WHWD-0126-SM-4OORS 50-59 years, male 15.6
GTEX-144GN-2126-SM-5O99D 50-59 years, male 15.4
GTEX-11P7K-0426-SM-5BC5H 30-39 years, male 15.3
GTEX-XAJ8-0126-SM-47JYG 40-49 years, male 15.2
GTEX-O5YT-0926-SM-48TDG 20-29 years, male 15.0
GTEX-1122O-0526-SM-5N9DM 60-69 years, female 14.9
GTEX-11NSD-0426-SM-5N9CR 20-29 years, male 14.8
GTEX-11VI4-0126-SM-5GU6Z 40-49 years, female 14.8
GTEX-Y114-0726-SM-4TT6U 50-59 years, female 14.7
GTEX-PW2O-0126-SM-48TC8 20-29 years, male 14.5
GTEX-QV31-0126-SM-447BP 30-39 years, male 14.5
GTEX-U3ZN-0126-SM-4DXUM 30-39 years, female 14.5
GTEX-XXEK-0126-SM-4BRVU 50-59 years, male 14.5
GTEX-YB5K-1926-SM-4VDT4 40-49 years, female 14.5
GTEX-YFCO-0926-SM-5LUA5 40-49 years, male 14.5
GTEX-OIZH-0926-SM-48TBR 50-59 years, male 14.1
GTEX-ZLWG-0426-SM-4WWFA 50-59 years, female 14.1
GTEX-147F3-0126-SM-5NQBJ 50-59 years, female 14.0
GTEX-T5JW-0126-SM-4DM6K 20-29 years, female 14.0
GTEX-146FR-1926-SM-5NQA6 60-69 years, female 13.9
GTEX-XMK1-0126-SM-4B65F 40-49 years, male 13.9
GTEX-131XE-1126-SM-5EGHW 50-59 years, male 13.7
GTEX-1399R-0226-SM-5IJGG 30-39 years, male 13.5
GTEX-13PL7-1126-SM-5MR5O 60-69 years, female 13.5
GTEX-Q734-0226-SM-48U1A 40-49 years, female 13.5
GTEX-VJYA-0126-SM-4KL1P 60-69 years, male 13.3
GTEX-13PVR-0326-SM-5RQJY 60-69 years, female 13.2
GTEX-11P81-1326-SM-5GU5S 30-39 years, female 13.1
GTEX-139YR-0426-SM-5IFFV 50-59 years, male 13.0
GTEX-Y8LW-0126-SM-4VBS1 50-59 years, female 13.0
GTEX-ZLFU-0526-SM-4WWBN 40-49 years, male 12.9
GTEX-ZZPU-0126-SM-5E446 50-59 years, female 12.9
GTEX-P4PP-0926-SM-48TBZ 30-39 years, female 12.7
GTEX-QDVN-0526-SM-48TZ4 50-59 years, male 12.7
GTEX-YB5E-0426-SM-5IFHR 40-49 years, male 12.7
GTEX-145MN-0126-SM-5RQHY 30-39 years, male 12.6
GTEX-Y3IK-0126-SM-4WWE9 50-59 years, female 12.4
GTEX-XPVG-0626-SM-4B65B 50-59 years, male 12.3
GTEX-13CF3-0226-SM-5J1NW 60-69 years, female 12.2
GTEX-11EQ9-0426-SM-5A5JY 30-39 years, male 12.1
GTEX-146FQ-0626-SM-5LU9U 30-39 years, male 12.0
GTEX-Q2AH-0226-SM-48U1I 40-49 years, male 12.0
GTEX-ZAB5-0526-SM-5CVMU 50-59 years, male 11.8
GTEX-1399S-0226-SM-5IFFG 30-39 years, female 11.6
GTEX-X4LF-0226-SM-4QAS8 50-59 years, male 11.6
GTEX-ZPU1-1026-SM-4YCEQ 40-49 years, male 11.6
GTEX-13X6H-0726-SM-5Q5BX 50-59 years, female 11.5
GTEX-ZDTT-1026-SM-5KM19 60-69 years, male 11.5
GTEX-13S86-0126-SM-5S2PI 40-49 years, male 11.3
GTEX-139T6-0226-SM-5IFGZ 50-59 years, male 11.2
GTEX-13N11-0126-SM-5KM2Z 50-59 years, female 11.2
GTEX-S3XE-0626-SM-4AD6B 50-59 years, male 11.2
GTEX-13FH7-1326-SM-5IFG8 50-59 years, female 11.1
GTEX-XV7Q-0126-SM-4BRVK 40-49 years, female 11.1
GTEX-1211K-0426-SM-5FQTP 60-69 years, female 11.0
GTEX-ZP4G-0326-SM-4YCEF 20-29 years, female 11.0
GTEX-PX3G-0926-SM-48U12 20-29 years, female 10.9
GTEX-QV44-0126-SM-4R1KH 50-59 years, male 10.8
GTEX-11XUK-0426-SM-5EQML 40-49 years, female 10.7
GTEX-117YX-2126-SM-5GIEL 50-59 years, male 10.5
GTEX-R55G-0226-SM-48FEI 40-49 years, female 10.5
GTEX-ZVZP-0726-SM-59HKA 50-59 years, male 10.5
GTEX-YEC4-0126-SM-4W21T 40-49 years, male 10.3
GTEX-U3ZH-0126-SM-4DXUK 30-39 years, male 10.2
GTEX-ZV6S-0826-SM-5NQ6Z 40-49 years, female 10.2
GTEX-ZYFG-0726-SM-5GIDX 60-69 years, female 10.2
GTEX-132QS-0226-SM-5IFFZ 60-69 years, male 10.1
GTEX-U4B1-0526-SM-4DXTK 40-49 years, male 10.1
GTEX-QCQG-0226-SM-48U28 50-59 years, female 9.8
GTEX-14DAR-0326-SM-5S2PS 50-59 years, male 9.6
GTEX-14E6E-1226-SM-5S2R5 30-39 years, male 9.3
GTEX-12WSK-0126-SM-5GCO7 40-49 years, female 9.2
GTEX-ZYWO-0226-SM-5GZX3 40-49 years, female 9.2
GTEX-12BJ1-0726-SM-5EGGF 60-69 years, male 8.7
GTEX-13U4I-1626-SM-5IFFR 40-49 years, female 8.2
GTEX-Y5LM-0326-SM-4VBRN 40-49 years, female 8.2
GTEX-131XG-0426-SM-5IFGD 50-59 years, female 7.9
GTEX-RUSQ-0126-SM-47JWV 50-59 years, male 7.2
Show all

SPLEEN - FANTOM5 CAGEi

Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.

Read more

Average Tags Per Million

6.6

FANTOM5 sample id

Sample description

Tags Per Million

Spleen
Tags Per Million: 6.6
FF:10025-101D7 39,50,70 years, male 6.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.